diff --git a/ants/label/label_overlap_measures.py b/ants/label/label_overlap_measures.py
index d5c25883..c11658bd 100644
--- a/ants/label/label_overlap_measures.py
+++ b/ants/label/label_overlap_measures.py
@@ -40,6 +40,6 @@ def label_overlap_measures(source_image, target_image):
     libfn = get_lib_fn("labelOverlapMeasures%iD" % source_image_int.dimension)
     df = libfn(source_image_int.pointer, target_image_int.pointer)
     df = pd.DataFrame(df)
-    df.Label[0] = "All"
-
+    with pd.option_context('mode.chained_assignment', None):
+        df.Label[0] = "All"
     return df