diff --git a/ci/init.js b/ci/init.js
index b54e29abd4d..7b15ed15151 100644
--- a/ci/init.js
+++ b/ci/init.js
@@ -1,11 +1,22 @@
 /* eslint-disable no-console */
 const tracer = require('../packages/dd-trace')
 const { isTrue } = require('../packages/dd-trace/src/util')
+const log = require('../packages/dd-trace/src/log')
 
 const isJestWorker = !!process.env.JEST_WORKER_ID
 const isCucumberWorker = !!process.env.CUCUMBER_WORKER_ID
 const isMochaWorker = !!process.env.MOCHA_WORKER_ID
 
+const packageManagers = [
+  'npm',
+  'yarn',
+  'pnpm'
+]
+
+const isPackageManager = () => {
+  return packageManagers.some(packageManager => process.argv[1]?.includes(`bin/${packageManager}`))
+}
+
 const options = {
   startupLogs: false,
   isCiVisibility: true,
@@ -14,6 +25,11 @@ const options = {
 
 let shouldInit = true
 
+if (isPackageManager()) {
+  log.debug('dd-trace is not initialized in a package manager.')
+  shouldInit = false
+}
+
 const isAgentlessEnabled = isTrue(process.env.DD_CIVISIBILITY_AGENTLESS_ENABLED)
 
 if (isAgentlessEnabled) {
diff --git a/integration-tests/test-api-manual.spec.js b/integration-tests/test-api-manual.spec.js
index 419c7c736c5..c403168206a 100644
--- a/integration-tests/test-api-manual.spec.js
+++ b/integration-tests/test-api-manual.spec.js
@@ -10,24 +10,20 @@ const {
   getCiVisAgentlessConfig
 } = require('./helpers')
 const { FakeCiVisIntake } = require('./ci-visibility-intake')
-const webAppServer = require('./ci-visibility/web-app-server')
 const {
   TEST_STATUS
 } = require('../packages/dd-trace/src/plugins/util/test')
 
 describe('test-api-manual', () => {
-  let sandbox, cwd, receiver, childProcess, webAppPort
+  let sandbox, cwd, receiver, childProcess
 
   before(async () => {
     sandbox = await createSandbox([], true)
     cwd = sandbox.folder
-    webAppPort = await getPort()
-    webAppServer.listen(webAppPort)
   })
 
   after(async () => {
     await sandbox.remove()
-    await new Promise(resolve => webAppServer.close(resolve))
   })
 
   beforeEach(async function () {
diff --git a/integration-tests/test-optimization-startup.spec.js b/integration-tests/test-optimization-startup.spec.js
new file mode 100644
index 00000000000..a15d49cf8ef
--- /dev/null
+++ b/integration-tests/test-optimization-startup.spec.js
@@ -0,0 +1,84 @@
+'use strict'
+
+const { exec } = require('child_process')
+
+const getPort = require('get-port')
+const { assert } = require('chai')
+
+const { createSandbox } = require('./helpers')
+const { FakeCiVisIntake } = require('./ci-visibility-intake')
+
+const packageManagers = ['yarn', 'npm', 'pnpm']
+
+describe('test optimization startup', () => {
+  let sandbox, cwd, receiver, childProcess, processOutput
+
+  before(async () => {
+    sandbox = await createSandbox(packageManagers, true)
+    cwd = sandbox.folder
+  })
+
+  after(async () => {
+    await sandbox.remove()
+  })
+
+  beforeEach(async function () {
+    processOutput = ''
+    const port = await getPort()
+    receiver = await new FakeCiVisIntake(port).start()
+  })
+
+  afterEach(async () => {
+    childProcess.kill()
+    await receiver.stop()
+  })
+
+  packageManagers.forEach(packageManager => {
+    it(`skips initialization for ${packageManager}`, (done) => {
+      childProcess = exec(`node ./node_modules/.bin/${packageManager} -v`,
+        {
+          cwd,
+          env: {
+            ...process.env,
+            NODE_OPTIONS: '-r dd-trace/ci/init',
+            DD_TRACE_DEBUG: '1'
+          },
+          stdio: 'pipe'
+        }
+      )
+
+      childProcess.stdout.on('data', (chunk) => {
+        processOutput += chunk.toString()
+      })
+
+      childProcess.on('exit', () => {
+        assert.include(processOutput, 'dd-trace is not initialized in a package manager')
+        done()
+      })
+    })
+  })
+
+  it('does not skip initialization for non package managers', (done) => {
+    childProcess = exec('node -e "console.log(\'hello!\')"',
+      {
+        cwd,
+        env: {
+          ...process.env,
+          NODE_OPTIONS: '-r dd-trace/ci/init',
+          DD_TRACE_DEBUG: '1'
+        },
+        stdio: 'pipe'
+      }
+    )
+
+    childProcess.stdout.on('data', (chunk) => {
+      processOutput += chunk.toString()
+    })
+
+    childProcess.on('exit', () => {
+      assert.include(processOutput, 'hello!')
+      assert.notInclude(processOutput, 'dd-trace is not initialized in a package manager')
+      done()
+    })
+  })
+})