diff --git a/agent_requirements.in b/agent_requirements.in
index 7fae78323f0a9..fcc26a9ef7d1a 100644
--- a/agent_requirements.in
+++ b/agent_requirements.in
@@ -23,7 +23,7 @@ cryptography==3.3.2; python_version < '3.0'
 cryptography==42.0.8; python_version > '3.0'
 ddtrace==0.32.2; sys_platform == 'win32' and python_version < '3.0'
 ddtrace==0.53.2; sys_platform != 'win32' and python_version < '3.0'
-ddtrace==1.11.2; python_version > '3.0'
+ddtrace==2.10.3; python_version > '3.0'
 dnspython==1.16.0; python_version < '3.0'
 dnspython==2.6.1; python_version > '3.0'
 enum34==1.1.10; python_version < '3.0'
diff --git a/datadog_checks_base/changelog.d/18215.added b/datadog_checks_base/changelog.d/18215.added
new file mode 100644
index 0000000000000..30afc24208f4d
--- /dev/null
+++ b/datadog_checks_base/changelog.d/18215.added
@@ -0,0 +1 @@
+Bump the ddtrace version to 2.10.3
\ No newline at end of file
diff --git a/datadog_checks_base/pyproject.toml b/datadog_checks_base/pyproject.toml
index 5829618fbef90..c96b9252f5984 100644
--- a/datadog_checks_base/pyproject.toml
+++ b/datadog_checks_base/pyproject.toml
@@ -46,7 +46,7 @@ deps = [
     "cryptography==42.0.8; python_version > '3.0'",
     "ddtrace==0.32.2; sys_platform == 'win32' and python_version < '3.0'",
     "ddtrace==0.53.2; sys_platform != 'win32' and python_version < '3.0'",
-    "ddtrace==1.11.2; python_version > '3.0'",
+    "ddtrace==2.10.3; python_version > '3.0'",
     "enum34==1.1.10; python_version < '3.0'",
     "importlib-metadata==2.1.3; python_version < '3.8'",
     "ipaddress==1.0.23; python_version < '3.0'",