diff --git a/requirements.txt b/requirements.txt
index 0e84d6355..0bdf48ffc 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -6,7 +6,7 @@ numpy
 networkx>=1.10
 sqlalchemy>=1
 sqlalchemy_utils
-biopython>=1.66
+biopython>=1.67
 intervaltree
 nose
 pyfaidx