diff --git a/models/AOP_1.ttl b/models/AOP_1.ttl index 62dcd7b1..ebd4fff1 100644 --- a/models/AOP_1.ttl +++ b/models/AOP_1.ttl @@ -1,54 +1,24 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Promotion, Hepatocelluar carcinoma"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "AOP 1"^^ . diff --git a/models/AOP_10.ttl b/models/AOP_10.ttl index a590ab16..a7b4dc4e 100644 --- a/models/AOP_10.ttl +++ b/models/AOP_10.ttl @@ -1,133 +1,76 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Parkinsonian motor deficits"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_17996 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0022851 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0051899 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000025 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007766 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050811 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007770 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007771 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007268 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060079 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-1 - rdf:type owl:NamedIndividual , - ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding - rdf:type owl:NamedIndividual , - ; - :GABA-gated%20chloride%20ion%20channel%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-5 - rdf:type owl:NamedIndividual , - ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding - rdf:type owl:NamedIndividual , - ; - :GABA-gated%20chloride%20ion%20channel%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-6 - rdf:type owl:NamedIndividual , - ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding ; - :GABA%20receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding - rdf:type owl:NamedIndividual , - ; - :GABA-gated%20chloride%20ion%20channel%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#chloride - rdf:type owl:NamedIndividual , - ; - :GABA-gated%20chloride%20ion%20channel%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#GABA-gated%20chloride%20ion%20channel%20activity - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission - rdf:type owl:NamedIndividual , - ; - :excitatory%20postsynaptic%20potential . + a . -### http://www.co-ode.org/ontologies/ont.owl#excitatory%20postsynaptic%20potential - rdf:type owl:NamedIndividual , - ; - :membrane%20depolarization . - -### http://www.co-ode.org/ontologies/ont.owl#membrane%20depolarization - rdf:type owl:NamedIndividual , - ; - :seizures . - -### http://www.co-ode.org/ontologies/ont.owl#seizures - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a , . + + "review"^^ ; + a ; + "Binding to the picrotoxin site of ionotropic GABA receptors leading to epileptic seizures in adult brain"^^ . diff --git a/models/AOP_100.ttl b/models/AOP_100.ttl index 231a07a4..f90b0de9 100644 --- a/models/AOP_100.ttl +++ b/models/AOP_100.ttl @@ -1,149 +1,95 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Testosterone synthesis in Leydig cells"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000013427 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004666 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013428 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15553 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001516 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000280 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0022414 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000003 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%201 - rdf:type owl:NamedIndividual , - ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin-endoperoxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%202 - rdf:type owl:NamedIndividual , - ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin-endoperoxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20F2alpha - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20F2alpha ; - :prostaglandin%20F2alpha ; - :prostaglandin%20F2alpha ; - :prostaglandin%20F2alpha . - -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - ; - :attraction-related%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20process - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#reproduction - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#attraction-related%20behavior - rdf:type owl:NamedIndividual , - ; - :reproductive%20process ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20F2alpha - rdf:type owl:NamedIndividual , - ; - :fertility ; - :fertility . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + , ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Cyclooxygenase inhibition leading to reproductive dysfunction via inhibition of female spawning behavior"^^ . diff --git a/models/AOP_101.ttl b/models/AOP_101.ttl index 71715f33..28042519 100644 --- a/models/AOP_101.ttl +++ b/models/AOP_101.ttl @@ -1,141 +1,82 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, testosterone level"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000013427 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004666 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013428 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/NBO_0000280 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0022414 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0000003 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26013 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0071834 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15553 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001516 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#pheromone - rdf:type owl:NamedIndividual , - ; - :mating%20pheromone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#mating%20pheromone%20secretion - rdf:type owl:NamedIndividual , - ; - :attraction-related%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#attraction-related%20behavior - rdf:type owl:NamedIndividual , - ; - :reproductive%20process ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20process - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#reproduction - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20F2alpha - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20F2alpha ; - :prostaglandin%20F2alpha ; - :prostaglandin%20F2alpha ; - :prostaglandin%20F2alpha . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20F2alpha - rdf:type owl:NamedIndividual , - ; - :mating%20pheromone%20secretion ; - :mating%20pheromone%20secretion ; - :mating%20pheromone%20secretion ; - :mating%20pheromone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#pheromone - rdf:type owl:NamedIndividual , - ; - :mating%20pheromone%20secretion . + a . -### http://www.co-ode.org/ontologies/ont.owl#mating%20pheromone%20secretion - rdf:type owl:NamedIndividual , - ; - :attraction-related%20behavior . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + , ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Cyclooxygenase inhibition leading to reproductive dysfunction via inhibition of pheromone release"^^ . diff --git a/models/AOP_102.ttl b/models/AOP_102.ttl index db397a74..800891a4 100644 --- a/models/AOP_102.ttl +++ b/models/AOP_102.ttl @@ -1,213 +1,128 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Translocator protein (TSPO)"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_15551 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D007987 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26764 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003707 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008315 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_58165 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0022414 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000003 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013427 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004666 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013428 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%201 - rdf:type owl:NamedIndividual , - ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin-endoperoxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%202 - rdf:type owl:NamedIndividual , - ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin-endoperoxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20E2 - rdf:type owl:NamedIndividual , - ; - :Gonadotropin%20Releasing%20Hormone ; - :Gonadotropin%20Releasing%20Hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Gonadotropin%20Releasing%20Hormone - rdf:type owl:NamedIndividual , - ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone - rdf:type owl:NamedIndividual , - ; - :steroid%20hormone ; - :steroid%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#steroid%20hormone - rdf:type owl:NamedIndividual , - ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#steroid%20hormone - rdf:type owl:NamedIndividual , - ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#steroid%20hormone%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :3%27%2C5%27-cyclic%20AMP%281-%29 ; - :3%27%2C5%27-cyclic%20AMP%281-%29 ; - :3%27%2C5%27-cyclic%20AMP%281-%29 ; - :3%27%2C5%27-cyclic%20AMP%281-%29 . - -### http://www.co-ode.org/ontologies/ont.owl#steroid%20hormone - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :3%27%2C5%27-cyclic%20AMP%281-%29 ; - :3%27%2C5%27-cyclic%20AMP%281-%29 ; - :3%27%2C5%27-cyclic%20AMP%281-%29 ; - :3%27%2C5%27-cyclic%20AMP%281-%29 . - -### http://www.co-ode.org/ontologies/ont.owl#3%27%2C5%27-cyclic%20AMP%281-%29 - rdf:type owl:NamedIndividual , - ; - :G2%2FMI%20transition%20of%20meiotic%20cell%20cycle ; - :G2%2FMI%20transition%20of%20meiotic%20cell%20cycle ; - :G2%2FMI%20transition%20of%20meiotic%20cell%20cycle ; - :G2%2FMI%20transition%20of%20meiotic%20cell%20cycle . - -### http://www.co-ode.org/ontologies/ont.owl#G2/MI%20transition%20of%20meiotic%20cell%20cycle - rdf:type owl:NamedIndividual , - ; - :reproductive%20process ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20process - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#reproduction - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + , ; + a , . + + ; + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Cyclooxygenase inhibition leading to reproductive dysfunction via interference with meiotic prophase I /metaphase I transition"^^ . diff --git a/models/AOP_103.ttl b/models/AOP_103.ttl index 1e17be48..ae8d8c08 100644 --- a/models/AOP_103.ttl +++ b/models/AOP_103.ttl @@ -1,215 +1,127 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Malformation, Male reproductive tract"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000013427 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004666 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013428 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15551 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D007987 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26764 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003707 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_Q9VNE1 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1902426 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007059 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0022414 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000003 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%201 - rdf:type owl:NamedIndividual , - ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin-endoperoxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%202 - rdf:type owl:NamedIndividual , - ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin-endoperoxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20E2 - rdf:type owl:NamedIndividual , - ; - :Gonadotropin%20Releasing%20Hormone ; - :Gonadotropin%20Releasing%20Hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Gonadotropin%20Releasing%20Hormone - rdf:type owl:NamedIndividual , - ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone - rdf:type owl:NamedIndividual , - ; - :steroid%20hormone ; - :steroid%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#steroid%20hormone - rdf:type owl:NamedIndividual , - ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#steroid%20hormone - rdf:type owl:NamedIndividual , - ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity ; - :steroid%20hormone%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#steroid%20hormone%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :deactivation%20of%20mitotic%20spindle%20assembly%20checkpoint . - -### http://www.co-ode.org/ontologies/ont.owl#steroid%20hormone - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :deactivation%20of%20mitotic%20spindle%20assembly%20checkpoint . - -### http://www.co-ode.org/ontologies/ont.owl#MAD2%20like%20protein%20%28fruit%20fly%29 - rdf:type owl:NamedIndividual , - ; - :deactivation%20of%20mitotic%20spindle%20assembly%20checkpoint ; - :deactivation%20of%20mitotic%20spindle%20assembly%20checkpoint ; - :deactivation%20of%20mitotic%20spindle%20assembly%20checkpoint ; - :deactivation%20of%20mitotic%20spindle%20assembly%20checkpoint . - -### http://www.co-ode.org/ontologies/ont.owl#deactivation%20of%20mitotic%20spindle%20assembly%20checkpoint - rdf:type owl:NamedIndividual , - ; - :chromosome%20segregation . - -### http://www.co-ode.org/ontologies/ont.owl#chromosome%20segregation - rdf:type owl:NamedIndividual , - ; - :reproductive%20process ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20process - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#reproduction - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + a . + + a . + + a . + + , ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Cyclooxygenase inhibition leading to reproductive dysfunction via interference with spindle assembly checkpoint"^^ . diff --git a/models/AOP_104.ttl b/models/AOP_104.ttl index 5abbd1d2..b523e0d2 100644 --- a/models/AOP_104.ttl +++ b/models/AOP_104.ttl @@ -1,93 +1,53 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "N/A, Androgen receptor, Antagonism"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_Q12809 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005216 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001978 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001508 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D001145 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#potassium%20voltage-gated%20channel%20subfamily%20H%20member%202%20%28human%29 - rdf:type owl:NamedIndividual , - ; - :ion%20channel%20activity ; - :ion%20channel%20activity ; - :ion%20channel%20activity ; - :ion%20channel%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#ion%20channel%20activity - rdf:type owl:NamedIndividual , - ; - :action%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#ATP-sensitive%20inward%20rectifier%20potassium%20channel%201 - rdf:type owl:NamedIndividual , - ; - :ion%20channel%20activity ; - :ion%20channel%20activity ; - :ion%20channel%20activity ; - :ion%20channel%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#ion%20channel%20activity - rdf:type owl:NamedIndividual , - ; - :action%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#action%20potential - rdf:type owl:NamedIndividual , - ; - :Arrhythmias%2C%20Cardiac . - -### http://www.co-ode.org/ontologies/ont.owl#Arrhythmias%2C%20Cardiac - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Altered ion channel activity leading impaired heart function"^^ . diff --git a/models/AOP_105.ttl b/models/AOP_105.ttl index 1f9f5f18..1b67b5d2 100644 --- a/models/AOP_105.ttl +++ b/models/AOP_105.ttl @@ -1,145 +1,79 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Alteration, Wnt pathway"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_P02761 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_1000507 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050673 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002292 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005488 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#major%20urinary%20protein%20%28rat%29 - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - ; - :major%20urinary%20protein%20%28rat%29 ; - :major%20urinary%20protein%20%28rat%29 ; - :major%20urinary%20protein%20%28rat%29 ; - :major%20urinary%20protein%20%28rat%29 . - -### http://www.co-ode.org/ontologies/ont.owl#major%20urinary%20protein%20%28rat%29 - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#kidney%20tubule%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :epithelial%20cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#kidney%20tubule%20cell - rdf:type owl:NamedIndividual , - ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#kidney%20tubule%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma ; - :Carcinoma%2C%20Renal%20Cell . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - ; - :Carcinoma%2C%20Renal%20Cell . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma%2C%20Renal%20Cell - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , , ; + a , . + + a . + + a . + + ; + a , . + + ; + , ; + , ; + , ; + , ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + a , . + + a . + + a . + + a . + + a , . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + "review"^^ ; + a ; + "Alpha2u-microglobulin cytotoxicity leading to renal tubular adenomas and carcinomas (in male rat)"^^ . diff --git a/models/AOP_106.ttl b/models/AOP_106.ttl index a6dc4992..c0009405 100644 --- a/models/AOP_106.ttl +++ b/models/AOP_106.ttl @@ -1,125 +1,76 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Feminisation or incomplete development, Primary and accessory male sex organs"^^xsd:string . - "review"^^xsd:string . - -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000028799 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0015631 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0045298 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005874 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007019 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007051 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0004023 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005694 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051305 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#tubulin - rdf:type owl:NamedIndividual , - ; - :tubulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#tubulin%20binding - rdf:type owl:NamedIndividual , - ; - :microtubule%20depolymerization . - -### http://www.co-ode.org/ontologies/ont.owl#tubulin%20complex - rdf:type owl:NamedIndividual , - ; - :microtubule%20depolymerization ; - :microtubule%20depolymerization ; - :microtubule%20depolymerization ; - :microtubule%20depolymerization . - -### http://www.co-ode.org/ontologies/ont.owl#microtubule - rdf:type owl:NamedIndividual , - ; - :microtubule%20depolymerization . - -### http://www.co-ode.org/ontologies/ont.owl#microtubule%20depolymerization - rdf:type owl:NamedIndividual , - ; - :spindle%20organization . - -### http://www.co-ode.org/ontologies/ont.owl#spindle - rdf:type owl:NamedIndividual , - ; - :spindle%20organization . - -### http://www.co-ode.org/ontologies/ont.owl#spindle%20organization - rdf:type owl:NamedIndividual , - ; - :chromosome%20movement%20towards%20spindle%20pole . - -### http://www.co-ode.org/ontologies/ont.owl#chromosome - rdf:type owl:NamedIndividual , - ; - :chromosome%20movement%20towards%20spindle%20pole . - -### http://www.co-ode.org/ontologies/ont.owl#chromosome%20movement%20towards%20spindle%20pole - rdf:type owl:NamedIndividual , - ; - :abnormal%20chromosome%20number . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20chromosome%20number - rdf:type owl:NamedIndividual , - ; - :abnormal%20chromosome%20number ; - :abnormal%20chromosome%20number . + a . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20chromosome%20number - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Chemical binding to tubulin in oocytes leading to aneuploid offspring"^^ . diff --git a/models/AOP_107.ttl b/models/AOP_107.ttl index f2635806..f8a0d06f 100644 --- a/models/AOP_107.ttl +++ b/models/AOP_107.ttl @@ -1,148 +1,93 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Altered, Transcription of genes by AR"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000011398 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000422 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000182 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072574 - rdf:type owl:Class . -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003902 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002009 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#nuclear%20receptor%20subfamily%201%20group%20I%20member%203 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :hepatocyte%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#mitogenic%20signaling%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :preneoplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte - rdf:type owl:NamedIndividual , - ; - :hepatocyte%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte%20proliferation - rdf:type owl:NamedIndividual , - ; - :preneoplasia . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20cell%20mass - rdf:type owl:NamedIndividual , - ; - :preneoplasia ; - :preneoplasia . - -### http://www.co-ode.org/ontologies/ont.owl#preneoplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + ; + a , . + + a . + + a . + + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + ; + ; + a , . + + "review"^^ ; + a ; + "Constitutive androstane receptor activation leading to hepatocellular adenomas and carcinomas in the mouse and the rat"^^ . diff --git a/models/AOP_108.ttl b/models/AOP_108.ttl index 9404081e..aeb03f1f 100644 --- a/models/AOP_108.ttl +++ b/models/AOP_108.ttl @@ -1,153 +1,93 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "N/A, Impairment of reproductive capacity"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001909 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000023575 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004738 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_Q63065 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0045333 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Pyruvate%20dehydrogenase%20%28acetyl-transferring%29%5D%20kinase%20isozyme%201%2C%20mitochondrial%20%28rat%29 - rdf:type owl:NamedIndividual , - ; - :pyruvate%20dehydrogenase%20activity ; - :pyruvate%20dehydrogenase%20activity ; - :pyruvate%20dehydrogenase%20activity ; - :pyruvate%20dehydrogenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#pyruvate%20dehydrogenase%20activity - rdf:type owl:NamedIndividual , - ; - :pyruvate%20dehydrogenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#pyruvate%20dehydrogenase%20%5Bubiquinone%5D - rdf:type owl:NamedIndividual , - ; - :pyruvate%20dehydrogenase%20activity ; - :pyruvate%20dehydrogenase%20activity ; - :pyruvate%20dehydrogenase%20activity ; - :pyruvate%20dehydrogenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#pyruvate%20dehydrogenase%20activity - rdf:type owl:NamedIndividual , - ; - :cellular%20respiration . - -### http://www.co-ode.org/ontologies/ont.owl#cellular%20respiration - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :leukocyte%20mediated%20cytotoxicity ; - :leukocyte%20mediated%20cytotoxicity . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Adenoma ; - :Adenoma ; - :Adenoma ; - :Carcinoma ; - :Carcinoma ; - :Carcinoma ; - :Carcinoma ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#leukocyte%20mediated%20cytotoxicity - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Adenoma ; - :Adenoma ; - :Adenoma ; - :Carcinoma ; - :Carcinoma ; - :Carcinoma ; - :Carcinoma ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + ; + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + ; + a , . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + "review"^^ ; + a ; + "Inhibition of pyruvate dehydrogenase kinase leading to hepatocellular adenomas and carcinomas (in mouse and rat)"^^ . diff --git a/models/AOP_109.ttl b/models/AOP_109.ttl index ca460948..c5ab7e07 100644 --- a/models/AOP_109.ttl +++ b/models/AOP_109.ttl @@ -1,114 +1,52 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Activation, AhR"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CL_0002328 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050673 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000158 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#bronchial%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :epithelial%20cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#bronchial%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#bronchial%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#bronchial%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :epithelial%20cell%20proliferation . - - - -################################################################# -# Object Statements -################################################################# - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + a . + + ; + a , . + + a . + + a . + + a , . + + a , . + + a . + + ; + a , . + + a . + + a . + + ; + , ; + , ; + , ; + , ; + a , . + + "review"^^ ; + a ; + "Cytotoxicity leading to bronchioloalveolar adenomas and carcinomas (in mouse)"^^ . diff --git a/models/AOP_11.ttl b/models/AOP_11.ttl index 0f3a2df5..0828606b 100644 --- a/models/AOP_11.ttl +++ b/models/AOP_11.ttl @@ -1,39 +1,18 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, Ecdysone receptor agonism"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000011397 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Percellome Toxicogenomics Approach for AOP Building: Case study on Pentachlorophenol"^^ . diff --git a/models/AOP_110.ttl b/models/AOP_110.ttl index ae3b3ed5..61171d9e 100644 --- a/models/AOP_110.ttl +++ b/models/AOP_110.ttl @@ -1,162 +1,99 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "dimerization, AHR/ARNT"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CL_0002258 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006984 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81567 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000015171 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008507 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#sodium/iodide%20cotransporter - rdf:type owl:NamedIndividual , - ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#sodium%3Aiodide%20symporter%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :Thyroid%20stimulating%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Thyroid%20stimulating%20hormone - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :hypertrophy . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :hypertrophy . - -### http://www.co-ode.org/ontologies/ont.owl#hypertrophy - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + a , . + + a . + + ; + ; + ; + ; + ; + a , . + + a . + + , ; + a , . + + a . + + a . + + a , . + + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + ; + a , . + + , ; + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Inhibition of iodide pump activity leading to follicular cell adenomas and carcinomas (in rat and mouse)"^^ . diff --git a/models/AOP_111.ttl b/models/AOP_111.ttl index b18b1af7..f569f0c0 100644 --- a/models/AOP_111.ttl +++ b/models/AOP_111.ttl @@ -1,116 +1,81 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Altered, Cardiovascular development/function"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004882 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005102 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000178 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001152 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002006 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :receptor%20binding ; - :receptor%20binding ; - :receptor%20binding ; - :receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#receptor%20binding - rdf:type owl:NamedIndividual , - ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#neoplasm - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone - rdf:type owl:NamedIndividual , - ; - :Leydig%20cell%20hyperplasia ; - :Leydig%20cell%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Leydig%20cell - rdf:type owl:NamedIndividual , - ; - :Leydig%20cell%20hyperplasia ; - :Leydig%20cell%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Leydig%20cell%20hyperplasia - rdf:type owl:NamedIndividual , - ; - :neoplasm ; - :neoplasm . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Decrease in androgen receptor activity leading to Leydig cell tumors (in rat)"^^ . diff --git a/models/AOP_112.ttl b/models/AOP_112.ttl index 58e27dd8..2e1836a3 100644 --- a/models/AOP_112.ttl +++ b/models/AOP_112.ttl @@ -1,131 +1,90 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, COX-2 expression"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0001963 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81580 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030284 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0042701 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0002656 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0009092 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20transmission%2C%20dopaminergic - rdf:type owl:NamedIndividual , - ; - :Prolactin ; - :Prolactin ; - :Prolactin ; - :Prolactin . - -### http://www.co-ode.org/ontologies/ont.owl#Prolactin - rdf:type owl:NamedIndividual , - ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor - rdf:type owl:NamedIndividual , - ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :progesterone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#progesterone - rdf:type owl:NamedIndividual , - ; - :progesterone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#progesterone%20secretion - rdf:type owl:NamedIndividual , - ; - :endometrium%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#glandular%20cell%20of%20endometrium - rdf:type owl:NamedIndividual , - ; - :endometrium%20hyperplasia ; - :endometrium%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#endometrium%20hyperplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Increased dopaminergic activity leading to endometrial adenocarcinomas (in Wistar rat)"^^ . diff --git a/models/AOP_113.ttl b/models/AOP_113.ttl index d6f9d7af..8fed25a3 100644 --- a/models/AOP_113.ttl +++ b/models/AOP_113.ttl @@ -1,95 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, Early Life Stage Mortality"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_Q94900 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005254 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_17996 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1902476 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0060081 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001393 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001399 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0000753 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000003 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#glutamate-gated%20chloride%20channel%20%28fruit%20fly%29 - rdf:type owl:NamedIndividual , - ; - :chloride%20channel%20activity ; - :chloride%20channel%20activity ; - :chloride%20channel%20activity ; - :chloride%20channel%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#chloride%20channel%20activity - rdf:type owl:NamedIndividual , - ; - :chloride%20transmembrane%20transport . + a . -### http://www.co-ode.org/ontologies/ont.owl#chloride - rdf:type owl:NamedIndividual , - ; - :chloride%20transmembrane%20transport . + a . -### http://www.co-ode.org/ontologies/ont.owl#chloride%20transmembrane%20transport - rdf:type owl:NamedIndividual , - ; - :membrane%20hyperpolarization . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20quality - rdf:type owl:NamedIndividual , - . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#membrane%20hyperpolarization - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Glutamate-gated chloride channel activation leading to acute mortality"^^ . diff --git a/models/AOP_114.ttl b/models/AOP_114.ttl index 174fd3e7..7fba37f3 100644 --- a/models/AOP_114.ttl +++ b/models/AOP_114.ttl @@ -1,143 +1,82 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Population growth rate"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_P32755 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003868 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_18186 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000575 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006954 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D010212 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#4-hydroxyphenylpyruvate%20dioxygenase%20%28rat%29 - rdf:type owl:NamedIndividual , - ; - :4-hydroxyphenylpyruvate%20dioxygenase%20activity ; - :4-hydroxyphenylpyruvate%20dioxygenase%20activity ; - :4-hydroxyphenylpyruvate%20dioxygenase%20activity ; - :4-hydroxyphenylpyruvate%20dioxygenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#4-hydroxyphenylpyruvate%20dioxygenase%20activity - rdf:type owl:NamedIndividual , - ; - :tyrosine ; - :tyrosine ; - :tyrosine ; - :tyrosine . - -### http://www.co-ode.org/ontologies/ont.owl#tyrosine - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#corneal%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#corneal%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response ; - :inflammatory%20response ; - :inflammatory%20response ; - :inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#corneal%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :papilloma ; - :papilloma ; - :papilloma ; - :papilloma ; - :Carcinoma ; - :Carcinoma ; - :Carcinoma ; - :Carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#papilloma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , , ; + , , ; + , , ; + , , ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "HPPD inhibition leading to corneal papillomas and carcinomas (in rat)"^^ . diff --git a/models/AOP_115.ttl b/models/AOP_115.ttl index 23ff3567..28273db2 100644 --- a/models/AOP_115.ttl +++ b/models/AOP_115.ttl @@ -1,110 +1,62 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Agonism, Androgen receptor"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CL_0000066 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006954 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005493 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D010212 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :stomach%20epithelial%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :stomach%20epithelial%20hyperplasia ; - :stomach%20epithelial%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#stomach%20epithelial%20hyperplasia - rdf:type owl:NamedIndividual , - ; - :papilloma ; - :Carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#papilloma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + , ; + , ; + , ; + , ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a , . + + a . + + a , . + + a . + + , ; + a , . + + "review"^^ ; + a ; + "Epithelial cytotoxicity leading to forestomach tumors (in mouse and rat)"^^ . diff --git a/models/AOP_116.ttl b/models/AOP_116.ttl index 82d8b78e..410fcd31 100644 --- a/models/AOP_116.ttl +++ b/models/AOP_116.ttl @@ -1,120 +1,74 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Testosterone synthesis by ovarian theca cells"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CL_1000494 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_1000507 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050673 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0004968 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002292 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#nephron%20tubule%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :epithelial%20cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#kidney%20tubule%20cell - rdf:type owl:NamedIndividual , - ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation ; - :epithelial%20cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :kidney%20epithelium%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#nephron%20tubule%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :kidney%20epithelium%20hyperplasia ; - :kidney%20epithelium%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#kidney%20epithelium%20hyperplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma ; - :Carcinoma%2C%20Renal%20Cell ; - :Carcinoma%2C%20Renal%20Cell . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - ; - :Carcinoma%2C%20Renal%20Cell . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma%2C%20Renal%20Cell - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + a , . + + a . + + a . + + a , . + + ; + a , . + + a . + + a . + + , ; + ; + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Cytotoxicity leading to renal tubular adenomas and carcinomas (in male rat) "^^ . diff --git a/models/AOP_117.ttl b/models/AOP_117.ttl index c1ebf8f8..4dd7b29e 100644 --- a/models/AOP_117.ttl +++ b/models/AOP_117.ttl @@ -1,140 +1,88 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, 17beta-estradiol synthesis by ovarian granulosa cells"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004882 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000422 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000182 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072574 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003902 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002009 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :hepatocyte%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#mitogenic%20signaling%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :preneoplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte - rdf:type owl:NamedIndividual , - ; - :hepatocyte%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte%20proliferation - rdf:type owl:NamedIndividual , - ; - :preneoplasia . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20cell%20mass - rdf:type owl:NamedIndividual , - ; - :preneoplasia ; - :preneoplasia . - -### http://www.co-ode.org/ontologies/ont.owl#preneoplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + , ; + a , . + + a . + + a . + + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + a , . + + , ; + ; + ; + a , . + + "review"^^ ; + a ; + "Androgen receptor activation leading to hepatocellular adenomas and carcinomas (in mouse and rat)"^^ . diff --git a/models/AOP_118.ttl b/models/AOP_118.ttl index 421f9f26..c40b39a2 100644 --- a/models/AOP_118.ttl +++ b/models/AOP_118.ttl @@ -1,120 +1,70 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Plasma 17beta-estradiol concentrations"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CL_0000182 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003902 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002009 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :preneoplasia . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20cell%20mass - rdf:type owl:NamedIndividual , - ; - :preneoplasia ; - :preneoplasia . - -### http://www.co-ode.org/ontologies/ont.owl#preneoplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a , . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + ; + ; + a , . + + , ; + ; + ; + a , . + + "review"^^ ; + a ; + "Chronic cytotoxicity leading to hepatocellular adenomas and carcinomas (in mouse and rat)"^^ . diff --git a/models/AOP_119.ttl b/models/AOP_119.ttl index 77496c38..ae16cd28 100644 --- a/models/AOP_119.ttl +++ b/models/AOP_119.ttl @@ -1,162 +1,99 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Vitellogenin synthesis in liver"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000016584 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004447 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0002258 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006984 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81567 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase - rdf:type owl:NamedIndividual , - ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :Thyroid%20stimulating%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Thyroid%20stimulating%20hormone - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :hypertrophy . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :hypertrophy . - -### http://www.co-ode.org/ontologies/ont.owl#hypertrophy - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + a , . + + a . + + ; + ; + ; + ; + ; + a , . + + a . + + , ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + a , . + + a . + + a . + + ; + a , . + + , ; + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Inhibition of thyroid peroxidase leading to follicular cell adenomas and carcinomas (in rat and mouse)"^^ . diff --git a/models/AOP_12.ttl b/models/AOP_12.ttl index 6e166197..155cddab 100644 --- a/models/AOP_12.ttl +++ b/models/AOP_12.ttl @@ -1,203 +1,105 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Circulating ecdysis triggering hormone"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0017146 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004972 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002229 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006816 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004716 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046903 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000129 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001847 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000127 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :secretion . - -### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor - rdf:type owl:NamedIndividual , - ; - :secretion ; - :secretion ; - :secretion ; - :secretion . - -### http://www.co-ode.org/ontologies/ont.owl#secretion - rdf:type owl:NamedIndividual , - ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :neurodegeneration ; - :neurodegeneration . - -### http://www.co-ode.org/ontologies/ont.owl#astrocyte - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :neurodegeneration ; - :neurodegeneration . - -### http://www.co-ode.org/ontologies/ont.owl#neurodegeneration - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :neurodegeneration ; - :neurodegeneration . - -### http://www.co-ode.org/ontologies/ont.owl#astrocyte - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :neurodegeneration ; - :neurodegeneration . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a , . + + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + "development"^^ ; + a ; + "Chronic binding of antagonist to N-methyl-D-aspartate receptors (NMDARs) during brain development leads to neurodegeneration with impairment in learning and memory in aging"^^ . diff --git a/models/AOP_120.ttl b/models/AOP_120.ttl index 8f188b59..f80d3471 100644 --- a/models/AOP_120.ttl +++ b/models/AOP_120.ttl @@ -1,113 +1,78 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Cumulative fecundity and spawning"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_P31214 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000178 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001152 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0061370 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002006 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#3-oxo-5-alpha-steroid%204-dehydrogenase%202%20%28rat%29 - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone - rdf:type owl:NamedIndividual , - ; - :Leydig%20cell%20hyperplasia ; - :Leydig%20cell%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Leydig%20cell - rdf:type owl:NamedIndividual , - ; - :Leydig%20cell%20hyperplasia ; - :Leydig%20cell%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Leydig%20cell%20hyperplasia - rdf:type owl:NamedIndividual , - ; - :neoplasm ; - :neoplasm . - -### http://www.co-ode.org/ontologies/ont.owl#neoplasm - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + a , . + + a . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Inhibition of 5Ī±-reductase leading to Leydig cell tumors (in rat)"^^ . diff --git a/models/AOP_121.ttl b/models/AOP_121.ttl index 2c9d901e..30198b6b 100644 --- a/models/AOP_121.ttl +++ b/models/AOP_121.ttl @@ -1,120 +1,70 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Plasma vitellogenin concentrations"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://id.nlm.nih.gov/mesh/D002137 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0011625 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000731 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Calculi - rdf:type owl:NamedIndividual , - ; - :cystolithiasis ; - :cystolithiasis . - -### http://www.co-ode.org/ontologies/ont.owl#cystolithiasis - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#urothelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#urothelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#urothelial%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + a . + + ; + , ; + , ; + , ; + , ; + a , . + + a . + + ; + a , . + + a . + + a . + + a , . + + a , . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + "review"^^ ; + a ; + "Urinary bladder calculi leading to urothelial papillomas and carcinomas (in mouse and rat)"^^ . diff --git a/models/AOP_122.ttl b/models/AOP_122.ttl index ea2f4c01..2581570b 100644 --- a/models/AOP_122.ttl +++ b/models/AOP_122.ttl @@ -1,271 +1,148 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Vitellogenin accumulation into oocytes and oocyte growth/development"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D064828 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_G5EGD2 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000008555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000038849 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0070330 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000006100 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006703 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009306 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006898 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048599 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Prolyl%20hydroxylases - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201%20%28Caenorhabditis%20elegans%29 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase%20isoform%201 - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity ; - :aromatase%20activity ; - :aromatase%20activity ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase%20activity - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase%20activity - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20secretion - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20growth - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20development - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + a , . + + a . + + ; + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , , ; + , ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + , , , , ; + , , , , ; + , , , , ; + , , , , ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Prolyl hydroxylase inhibition leading to reproductive dysfunction via increased HIF1 heterodimer formation"^^ . diff --git a/models/AOP_123.ttl b/models/AOP_123.ttl index 2f1ea6bc..8fb17f60 100644 --- a/models/AOP_123.ttl +++ b/models/AOP_123.ttl @@ -1,281 +1,140 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Gonadotropins, circulating concentrations"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000008555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_G5EGD2 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000038849 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0070330 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000006100 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006703 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009306 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006898 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048599 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201%20%28Caenorhabditis%20elegans%29 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase%20isoform%201 - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity ; - :aromatase%20activity ; - :aromatase%20activity ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase%20activity - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase%20activity - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20secretion - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20growth - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20development - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + , ; + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , , ; + , ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + , , , , ; + , , , , ; + , , , , ; + , , , , ; + a , . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Unknown MIE leading to reproductive dysfunction via increased HIF-1alpha transcription"^^ . diff --git a/models/AOP_124.ttl b/models/AOP_124.ttl index 41098229..86824a38 100644 --- a/models/AOP_124.ttl +++ b/models/AOP_124.ttl @@ -1,132 +1,80 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Population growth rate"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000008636 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0042282 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_25350 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16113 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006695 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030301 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17002 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000079 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#3-hydroxy-3-methylglutaryl-coenzyme%20A%20reductase - rdf:type owl:NamedIndividual , - ; - :hydroxymethylglutaryl-CoA%20reductase%20activity ; - :hydroxymethylglutaryl-CoA%20reductase%20activity ; - :hydroxymethylglutaryl-CoA%20reductase%20activity ; - :hydroxymethylglutaryl-CoA%20reductase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#hydroxymethylglutaryl-CoA%20reductase%20activity - rdf:type owl:NamedIndividual , - ; - :mevalonate ; - :mevalonate ; - :mevalonate ; - :mevalonate . - -### http://www.co-ode.org/ontologies/ont.owl#mevalonate - rdf:type owl:NamedIndividual , - ; - :cholesterol%20biosynthetic%20process ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol - rdf:type owl:NamedIndividual , - ; - :cholesterol%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol - rdf:type owl:NamedIndividual , - ; - :cholesterol%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol%20transport - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cholesteryl%20ester - rdf:type owl:NamedIndividual , - ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol%20transport - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a , . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + , ; + ; + a , . + + "review"^^ ; + a ; + "HMG-CoA reductase inhibition leading to decreased fertility"^^ . diff --git a/models/AOP_126.ttl b/models/AOP_126.ttl index 8c5759e5..6784661a 100644 --- a/models/AOP_126.ttl +++ b/models/AOP_126.ttl @@ -1,86 +1,52 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Plasma 17beta-estradiol concentrations"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_18357 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0051380 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000001186 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_P01101 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D007987 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046879 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0033684 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001928 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0060473 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046903 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0060387 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035037 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0004023 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001921 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . + a . + a . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Alpha-noradrenergic antagonism leads to reduced fecundity via delayed ovulation"^^ . diff --git a/models/AOP_128.ttl b/models/AOP_128.ttl index ca9ec91f..1e8334aa 100644 --- a/models/AOP_128.ttl +++ b/models/AOP_128.ttl @@ -1,217 +1,110 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Vitellogenin accumulation into oocytes and oocyte growth/development"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0002113 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/Q000633 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0003094 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0005524 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_29101 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0070293 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16737 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005332 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0009773 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D004106 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0011899 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048102 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MI_0613 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :creatinine ; - :creatinine ; - :creatinine ; - :creatinine ; - :abnormal%20amino%20acid%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :podocyte%20vacuolization ; - :podocyte%20vacuolization . - -### http://www.co-ode.org/ontologies/ont.owl#renal%20tubule - rdf:type owl:NamedIndividual , - ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death . + a . -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#renal%20tubule - rdf:type owl:NamedIndividual , - ; - :Dilatation . - -### http://www.co-ode.org/ontologies/ont.owl#Dilatation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#podocyte%20vacuolization - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#creatinine - rdf:type owl:NamedIndividual , - ; - :podocyte%20vacuolization ; - :podocyte%20vacuolization . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20amino%20acid%20level - rdf:type owl:NamedIndividual , - ; - :podocyte%20vacuolization ; - :podocyte%20vacuolization . - -### http://www.co-ode.org/ontologies/ont.owl#renal%20tubule - rdf:type owl:NamedIndividual , - ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#renal%20tubule - rdf:type owl:NamedIndividual , - ; - :Dilatation . - -### http://www.co-ode.org/ontologies/ont.owl#Dilatation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#podocyte%20vacuolization - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#kidney - rdf:type owl:NamedIndividual , - ; - :toxicity . - -### http://www.co-ode.org/ontologies/ont.owl#toxicity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#kidney - rdf:type owl:NamedIndividual , - ; - :toxicity . - -### http://www.co-ode.org/ontologies/ont.owl#toxicity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#kidney - rdf:type owl:NamedIndividual , - ; - :toxicity . - -### http://www.co-ode.org/ontologies/ont.owl#toxicity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#kidney - rdf:type owl:NamedIndividual , - ; - :toxicity . - -### http://www.co-ode.org/ontologies/ont.owl#toxicity - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + ; + a , . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a , . + + ; + ; + a , . + + a , . + + a , . + + ; + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Kidney dysfunction by decreased thyroid hormone"^^ . diff --git a/models/AOP_13.ttl b/models/AOP_13.ttl index 68420627..79ebacc5 100644 --- a/models/AOP_13.ttl +++ b/models/AOP_13.ttl @@ -1,210 +1,111 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, Incomplete ecdysis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006816 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0017146 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004972 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004716 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046903 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030425 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048813 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0045202 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007416 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0099536 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_14321 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0014047 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :secretion . - -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor - rdf:type owl:NamedIndividual , - ; - :secretion ; - :secretion ; - :secretion ; - :secretion . - -### http://www.co-ode.org/ontologies/ont.owl#secretion - rdf:type owl:NamedIndividual , - ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#dendrite - rdf:type owl:NamedIndividual , - ; - :dendrite%20morphogenesis . - -### http://www.co-ode.org/ontologies/ont.owl#dendrite%20morphogenesis - rdf:type owl:NamedIndividual , - ; - :synapse%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#glutamate%281-%29 - rdf:type owl:NamedIndividual , - ; - :glutamate%20secretion ; - :glutamate%20secretion ; - :glutamate%20secretion ; - :glutamate%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#glutamate%20secretion - rdf:type owl:NamedIndividual , - ; - :synapse%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#synapse - rdf:type owl:NamedIndividual , - ; - :synapse%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#synapse%20assembly - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#synapse - rdf:type owl:NamedIndividual , - ; - :synapse%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#synapse%20assembly - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :synapse%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#synapse - rdf:type owl:NamedIndividual , - ; - :synapse%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#synapse%20assembly - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a , . + + a , . + + a . + + , ; + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + "development"^^ ; + a ; + "Chronic binding of antagonist to N-methyl-D-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities"^^ . diff --git a/models/AOP_130.ttl b/models/AOP_130.ttl index d891a45f..f4dfc0fe 100644 --- a/models/AOP_130.ttl +++ b/models/AOP_130.ttl @@ -1,231 +1,95 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Cumulative fecundity and spawning"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_Q53H76 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004620 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/FMA_67514 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005764 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048102 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/HP_0001414 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0014045 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002107 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003333 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#phospholipase%20A1%20member%20A%20%28human%29 - rdf:type owl:NamedIndividual , - ; - :phospholipase%20activity ; - :phospholipase%20activity ; - :phospholipase%20activity ; - :phospholipase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#phospholipase%20activity - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#Lipid%20bilayer%20of%20wall%20of%20lysosome - rdf:type owl:NamedIndividual , - ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#lysosome - rdf:type owl:NamedIndividual , - ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death ; - :autophagic%20cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#autophagic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Mallory%20bodies . - -### http://www.co-ode.org/ontologies/ont.owl#Microvesicular%20hepatic%20steatosis - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#Mallory%20bodies - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#Microvesicular%20hepatic%20steatosis - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#Mallory%20bodies - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#Microvesicular%20hepatic%20steatosis - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#Mallory%20bodies - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#Microvesicular%20hepatic%20steatosis - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#Mallory%20bodies - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#liver - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#liver%20fibrosis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#liver - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#liver%20fibrosis - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + a , . + + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Phospholipase A2 (LPLA2) inhibitors leading to hepatotoxicity"^^ . diff --git a/models/AOP_131.ttl b/models/AOP_131.ttl index 6651a0f5..d97dd17c 100644 --- a/models/AOP_131.ttl +++ b/models/AOP_131.ttl @@ -1,150 +1,99 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Plasma vitellogenin concentrations"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_27258 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000017134 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26214 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005654 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000006102 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_P79761 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#cytochrome%20P450%201A2 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :uroporphyrinogen ; - :uroporphyrinogen ; - :uroporphyrinogen ; - :uroporphyrinogen . - -### http://www.co-ode.org/ontologies/ont.owl#cytochrome%20P450%201A5%20%28chicken%29 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :uroporphyrinogen ; - :uroporphyrinogen ; - :uroporphyrinogen ; - :uroporphyrinogen . - -### http://www.co-ode.org/ontologies/ont.owl#uroporphyrinogen - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#uroporphyrinogen%20decarboxylase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :porphyrins ; - :porphyrins ; - :porphyrins ; - :porphyrins . - -### http://www.co-ode.org/ontologies/ont.owl#porphyrins - rdf:type owl:NamedIndividual , - ; - :porphyria ; - :porphyria . - -### http://www.co-ode.org/ontologies/ont.owl#porphyria - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to uroporphyria"^^ . diff --git a/models/AOP_134.ttl b/models/AOP_134.ttl index 8cc86215..16371dd1 100644 --- a/models/AOP_134.ttl +++ b/models/AOP_134.ttl @@ -1,193 +1,119 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Disruption, Mitochondrial electron transport chain"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000015171 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008507 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_16382 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015705 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010817 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002421 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007420 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0045202 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007268 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050890 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#sodium/iodide%20cotransporter - rdf:type owl:NamedIndividual , - ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#sodium%3Aiodide%20symporter%20activity - rdf:type owl:NamedIndividual , - ; - :iodide%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#iodide - rdf:type owl:NamedIndividual , - ; - :iodide%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20transport - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20hormone%20levels - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - ; - :brain%20development . - -### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation - rdf:type owl:NamedIndividual , - ; - :brain%20development ; - :brain%20development ; - :brain%20development ; - :brain%20development . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20development - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#synapse - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission - rdf:type owl:NamedIndividual , - ; - :learning%20or%20memory ; - :cognition . - -### http://www.co-ode.org/ontologies/ont.owl#learning%20or%20memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cognition - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + , ; + a , . + + a , . + + , ; + , ; + , ; + , ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Sodium Iodide Symporter (NIS) Inhibition and Subsequent Adverse Neurodevelopmental Outcomes in Mammals"^^ . diff --git a/models/AOP_136.ttl b/models/AOP_136.ttl index 022625e4..70b5e3a6 100644 --- a/models/AOP_136.ttl +++ b/models/AOP_136.ttl @@ -1,135 +1,91 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, Reactive Oxygen Species production"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0051453 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/UBERON_0001997 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D001284 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0070265 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D008679 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001909 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0005386 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002006 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20intracellular%20pH - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :leukocyte%20mediated%20cytotoxicity . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :atrophy ; - :necrotic%20cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#leukocyte%20mediated%20cytotoxicity - rdf:type owl:NamedIndividual , - ; - :atrophy ; - :necrotic%20cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#olfactory%20epithelium - rdf:type owl:NamedIndividual , - ; - :atrophy . - -### http://www.co-ode.org/ontologies/ont.owl#atrophy - rdf:type owl:NamedIndividual , - ; - :Metaplasia . - -### http://www.co-ode.org/ontologies/ont.owl#necrotic%20cell%20death - rdf:type owl:NamedIndividual , - ; - :Metaplasia ; - :Metaplasia ; - :Metaplasia ; - :Metaplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Metaplasia - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#olfactory%20segment%20of%20nasal%20mucosa - rdf:type owl:NamedIndividual , - ; - :neoplasm ; - :neoplasm . + a . -### http://www.co-ode.org/ontologies/ont.owl#neoplasm - rdf:type owl:NamedIndividual , - . + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a , . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + a , . + + , ; + a , . + + "review"^^ ; + a ; + "Intracellular Acidification Induced Olfactory Epithelial Injury Leading to Site of Contact Nasal Tumors"^^ . diff --git a/models/AOP_138.ttl b/models/AOP_138.ttl index 678f6b9f..3bdedd9d 100644 --- a/models/AOP_138.ttl +++ b/models/AOP_138.ttl @@ -1,115 +1,73 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased, Long-term potentiation (LTP)"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000014993 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_27226 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0004154 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26216 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D001145 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#solute%20carrier%20family%2022%20member%206 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :uric%20acid ; - :uric%20acid ; - :uric%20acid ; - :uric%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#uric%20acid - rdf:type owl:NamedIndividual , - ; - :uric%20acid ; - :uric%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#uric%20acid - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#potassium%20atom - rdf:type owl:NamedIndividual , - ; - :Arrhythmias%2C%20Cardiac ; - :Arrhythmias%2C%20Cardiac . - -### http://www.co-ode.org/ontologies/ont.owl#Arrhythmias%2C%20Cardiac - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#uric%20acid - rdf:type owl:NamedIndividual , - ; - :uric%20acid ; - :uric%20acid . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + "review"^^ ; + a ; + "Organic anion transporter (OAT1) inhibition leading to renal failure and mortality"^^ . diff --git a/models/AOP_139.ttl b/models/AOP_139.ttl index 876db267..30a60a2a 100644 --- a/models/AOP_139.ttl +++ b/models/AOP_139.ttl @@ -1,74 +1,37 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Oxidative damage"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006305 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009369 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + , ; + , ; + , ; + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20alkylation ; - :DNA%20alkylation ; - :DNA%20alkylation ; - :DNA%20alkylation . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#DNA%20alkylation - rdf:type owl:NamedIndividual , - ; - :DNA%20repair . + a , . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . + a . -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - . + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Alkylation of DNA leading to cancer 1"^^ . diff --git a/models/AOP_14.ttl b/models/AOP_14.ttl index e3506901..77edbda9 100644 --- a/models/AOP_14.ttl +++ b/models/AOP_14.ttl @@ -1,138 +1,93 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Abdominal muscle contraction"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000011406 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004883 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001753 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007249 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002534 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000542 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000003292 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007252 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D004198 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002405 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0044414 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor - rdf:type owl:NamedIndividual , - ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :I-kappaB%20phosphorylation . - -### http://www.co-ode.org/ontologies/ont.owl#NF-kappa-B%20inhibitor - rdf:type owl:NamedIndividual , - ; - :I-kappaB%20phosphorylation ; - :I-kappaB%20phosphorylation ; - :I-kappaB%20phosphorylation ; - :I-kappaB%20phosphorylation . - -### http://www.co-ode.org/ontologies/ont.owl#I-kappaB%20phosphorylation - rdf:type owl:NamedIndividual , - ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#transcription%20factor%20NF-kappa-B%20subunit - rdf:type owl:NamedIndividual , - ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#I-kappaB%20kinase/NF-kappaB%20signaling - rdf:type owl:NamedIndividual , - ; - :cytokine%20production%20involved%20in%20inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#cytokine%20production%20involved%20in%20inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :lymphocyte ; - :lymphocyte ; - :lymphocyte ; - :lymphocyte . - -### http://www.co-ode.org/ontologies/ont.owl#lymphocyte - rdf:type owl:NamedIndividual , - ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses . - -### http://www.co-ode.org/ontologies/ont.owl#immune%20system - rdf:type owl:NamedIndividual , - ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses . - -### http://www.co-ode.org/ontologies/ont.owl#suppression%20of%20host%20defenses - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Glucocorticoid Receptor Activation Leading to Increased Disease Susceptibility"^^ . diff --git a/models/AOP_141.ttl b/models/AOP_141.ttl index 68ed94ff..73d1c819 100644 --- a/models/AOP_141.ttl +++ b/models/AOP_141.ttl @@ -1,72 +1,40 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation of specific nuclear receptors, Transcriptional change"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009369 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006305 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . + ; + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - ; - :mutation . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . + a . -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - . + a , . + a . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "AOP 141"^^ . diff --git a/models/AOP_144.ttl b/models/AOP_144.ttl index c7b43597..8296c538 100644 --- a/models/AOP_144.ttl +++ b/models/AOP_144.ttl @@ -1,178 +1,121 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, Inflammation"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005765 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006897 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005764 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002526 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000738 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002263 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000632 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0035733 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_3815 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032964 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002107 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003333 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#lysosomal%20membrane - rdf:type owl:NamedIndividual , - ; - :endocytosis ; - :endocytosis ; - :endocytosis ; - :endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#endocytosis - rdf:type owl:NamedIndividual , - ; - :organelle%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#lysosome - rdf:type owl:NamedIndividual , - ; - :organelle%20disassembly ; - :organelle%20disassembly ; - :organelle%20disassembly ; - :organelle%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#organelle%20disassembly - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :acute%20inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#acute%20inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :cell%20activation%20involved%20in%20immune%20response . - -### http://www.co-ode.org/ontologies/ont.owl#leukocyte - rdf:type owl:NamedIndividual , - ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - ; - :hepatic%20stellate%20cell%20activation . - -### http://www.co-ode.org/ontologies/ont.owl#hepatic%20stellate%20cell - rdf:type owl:NamedIndividual , - ; - :hepatic%20stellate%20cell%20activation ; - :hepatic%20stellate%20cell%20activation ; - :hepatic%20stellate%20cell%20activation ; - :hepatic%20stellate%20cell%20activation . - -### http://www.co-ode.org/ontologies/ont.owl#hepatic%20stellate%20cell%20activation - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#collagen - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#collagen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#liver - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#liver%20fibrosis - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + a , . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Endocytic lysosomal uptake leading to liver fibrosis"^^ . diff --git a/models/AOP_148.ttl b/models/AOP_148.ttl index 85a7956c..9f66765f 100644 --- a/models/AOP_148.ttl +++ b/models/AOP_148.ttl @@ -1,205 +1,96 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, Cyclooxygenase activity"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CL_0000160 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D008679 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000067 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000006933 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005006 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0016310 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000031343 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006412 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_0002327 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_1000143 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0070254 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#epidermal%20growth%20factor%20receptor - rdf:type owl:NamedIndividual , - ; - :epidermal%20growth%20factor-activated%20receptor%20activity ; - :epidermal%20growth%20factor-activated%20receptor%20activity ; - :epidermal%20growth%20factor-activated%20receptor%20activity ; - :epidermal%20growth%20factor-activated%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#epidermal%20growth%20factor-activated%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#epidermal%20growth%20factor%20receptor - rdf:type owl:NamedIndividual , - ; - :phosphorylation ; - :phosphorylation ; - :phosphorylation ; - :phosphorylation . - -### http://www.co-ode.org/ontologies/ont.owl#phosphorylation - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#ciliated%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :apoptotic%20process ; - :apoptotic%20process ; - :apoptotic%20process ; - :apoptotic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - ; - :Metaplasia . - -### http://www.co-ode.org/ontologies/ont.owl#goblet%20cell - rdf:type owl:NamedIndividual , - ; - :Metaplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Metaplasia - rdf:type owl:NamedIndividual , - ; - :mucus%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#goblet%20cell - rdf:type owl:NamedIndividual , - ; - :Metaplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Metaplasia - rdf:type owl:NamedIndividual , - ; - :mucus%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#lung%20goblet%20cell - rdf:type owl:NamedIndividual , - ; - :mucus%20secretion ; - :mucus%20secretion ; - :mucus%20secretion ; - :mucus%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#mucus%20secretion - rdf:type owl:NamedIndividual , - ; - :respiratory%20function%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#goblet%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#goblet%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :mucus%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#lung%20goblet%20cell - rdf:type owl:NamedIndividual , - ; - :mucus%20secretion ; - :mucus%20secretion ; - :mucus%20secretion ; - :mucus%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#mucus%20secretion - rdf:type owl:NamedIndividual , - ; - :respiratory%20function%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#lung%20goblet%20cell - rdf:type owl:NamedIndividual , - ; - :mucus%20secretion ; - :mucus%20secretion ; - :mucus%20secretion ; - :mucus%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#mucus%20secretion - rdf:type owl:NamedIndividual , - ; - :respiratory%20function%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20function%20trait - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + , ; + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "EGFR Activation Leading to Decreased Lung Function"^^ . diff --git a/models/AOP_149.ttl b/models/AOP_149.ttl index 5e689aef..c5282c62 100644 --- a/models/AOP_149.ttl +++ b/models/AOP_149.ttl @@ -1,236 +1,136 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Prostaglandin E2 concentration"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011328 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010731 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_32460 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007893 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903009 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15372 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009058 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16480 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006809 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0001981 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0042311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0004878 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000231 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000029189 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :protein%20glutathionylation ; - :protein%20glutathionylation ; - :protein%20glutathionylation ; - :protein%20glutathionylation . - -### http://www.co-ode.org/ontologies/ont.owl#GTP%20cyclohydrolase%201 - rdf:type owl:NamedIndividual , - ; - :proteasome%20complex%20disassembly ; - :proteasome%20complex%20disassembly ; - :proteasome%20complex%20disassembly ; - :proteasome%20complex%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#proteasome%20complex%20disassembly - rdf:type owl:NamedIndividual , - ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide%20synthase%2C%20endothelial - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#5%2C6%2C7%2C8-tetrahydrobiopterin - rdf:type owl:NamedIndividual , - ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide%20synthase%2C%20endothelial - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :vasodilation . - -### http://www.co-ode.org/ontologies/ont.owl#blood%20vessel - rdf:type owl:NamedIndividual , - ; - :vasodilation ; - :vasodilation ; - :vasodilation ; - :vasodilation . - -### http://www.co-ode.org/ontologies/ont.owl#vasodilation - rdf:type owl:NamedIndividual , - ; - :increased%20systemic%20vascular%20resistance . - -### http://www.co-ode.org/ontologies/ont.owl#increased%20systemic%20vascular%20resistance - rdf:type owl:NamedIndividual , - ; - :hypertension ; - :hypertension . - -### http://www.co-ode.org/ontologies/ont.owl#hypertension - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :vasodilation . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide%20synthase%2C%20endothelial - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#AKT%20kinase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide%20synthase%2C%20endothelial - rdf:type owl:NamedIndividual , - ; - :protein%20glutathionylation ; - :protein%20glutathionylation ; - :protein%20glutathionylation ; - :protein%20glutathionylation . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20glutathionylation - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial . - -### http://www.co-ode.org/ontologies/ont.owl#cysteine%20residue - rdf:type owl:NamedIndividual , - ; - :protein%20glutathionylation ; - :protein%20glutathionylation ; - :protein%20glutathionylation ; - :protein%20glutathionylation . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20glutathionylation - rdf:type owl:NamedIndividual , - ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial ; - :nitric%20oxide%20synthase%2C%20endothelial . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + a , . + + ; + a , . + + , ; + , ; + , , ; + , ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Peptide Oxidation Leading to Hypertension"^^ . diff --git a/models/AOP_15.ttl b/models/AOP_15.ttl index 2f139501..17dfe9cc 100644 --- a/models/AOP_15.ttl +++ b/models/AOP_15.ttl @@ -1,92 +1,42 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, Nuclear receptor E75b gene expression"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006305 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20alkylation ; - :DNA%20alkylation ; - :DNA%20alkylation ; - :DNA%20alkylation . - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20alkylation - rdf:type owl:NamedIndividual , - ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + ; + a , . + + a . + + ; + a , . + + "review"^^ ; + a ; + "Alkylation of DNA in male pre-meiotic germ cells leading to heritable mutations"^^ . diff --git a/models/AOP_150.ttl b/models/AOP_150.ttl index 2482aba9..5073f905 100644 --- a/models/AOP_150.ttl +++ b/models/AOP_150.ttl @@ -1,213 +1,117 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Ca and HCO3 transport to shell gland"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046983 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004303 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000008555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003158 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001544 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0004535 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072358 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0008762 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000017284 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0008469 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :abnormal%20protein%20level . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :abnormal%20protein%20level . - -### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20A - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :endothelium%20development . - -### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20A - rdf:type owl:NamedIndividual , - ; - :abnormal%20protein%20level ; - :abnormal%20protein%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20protein%20level - rdf:type owl:NamedIndividual , - ; - :endothelium%20development ; - :endothelium%20development . - -### http://www.co-ode.org/ontologies/ont.owl#endothelium%20development - rdf:type owl:NamedIndividual , - ; - :abnormal%20cardiovascular%20system%20physiology ; - :cardiovascular%20system%20development . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20cardiovascular%20system%20physiology - rdf:type owl:NamedIndividual , - ; - :embryonic%20lethality ; - :embryonic%20lethality ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#cardiovascular%20system - rdf:type owl:NamedIndividual , - ; - :cardiovascular%20system%20development ; - :cardiovascular%20system%20development ; - :cardiovascular%20system%20development ; - :cardiovascular%20system%20development . - -### http://www.co-ode.org/ontologies/ont.owl#cardiovascular%20system%20development - rdf:type owl:NamedIndividual , - ; - :embryonic%20lethality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#embryonic%20lethality - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + ; + a , . + + a . + + a . + + a . + + a . + + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to early life stage mortality, via reduced VEGF"^^ . diff --git a/models/AOP_151.ttl b/models/AOP_151.ttl index 9aad37fb..5d3466a4 100644 --- a/models/AOP_151.ttl +++ b/models/AOP_151.ttl @@ -1,153 +1,75 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Eggshell thickness"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046983 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004303 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000008555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000017284 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0008469 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :abnormal%20protein%20level . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :abnormal%20protein%20level . - -### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20A - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20A - rdf:type owl:NamedIndividual , - ; - :abnormal%20protein%20level ; - :abnormal%20protein%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20protein%20level - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "AhR activation leading to preeclampsia"^^ . diff --git a/models/AOP_152.ttl b/models/AOP_152.ttl index 5f85a0ca..e392210e 100644 --- a/models/AOP_152.ttl +++ b/models/AOP_152.ttl @@ -1,137 +1,87 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "N/A, Gap"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000016801 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0005488 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006810 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008152 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010817 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002421 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007420 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0045202 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007268 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050890 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#transthyretin - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - ; - :thyroxine ; - :thyroxine ; - :thyroxine ; - :thyroxine . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :thyroxine ; - :thyroxine . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#metabolic%20process - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + ; + ; + ; + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + "review"^^ ; + a ; + "Interference with thyroid serum binding protein transthyretin and subsequent adverse human neurodevelopmental toxicity "^^ . diff --git a/models/AOP_153.ttl b/models/AOP_153.ttl index 05ddfa02..0646b813 100644 --- a/models/AOP_153.ttl +++ b/models/AOP_153.ttl @@ -1,72 +1,40 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Reproductive failure"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000006100 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006703 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_50114 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_Q7TSB7 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007269 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D007987 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046879 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0032275 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042698 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aromatase Inhibition leading to Ovulation Inhibition and Decreased Fertility in Female Rats"^^ . diff --git a/models/AOP_154.ttl b/models/AOP_154.ttl index 73bfaf11..0ad82509 100644 --- a/models/AOP_154.ttl +++ b/models/AOP_154.ttl @@ -1,155 +1,91 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Agonism, Estrogen receptor"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003112 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MI_0254 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000011161 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002534 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001775 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D007165 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001379 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032623 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001391 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032633 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007535 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005488 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/TAIR_AT5G64350 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#FK506-binding%20protein%2015 - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - ; - :genetic%20interference . - -### http://www.co-ode.org/ontologies/ont.owl#FKBP12%20%28Arabidopsis%20thaliana%29 - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - ; - :genetic%20interference . - -### http://www.co-ode.org/ontologies/ont.owl#NFAT%20protein - rdf:type owl:NamedIndividual , - ; - :genetic%20interference . - -### http://www.co-ode.org/ontologies/ont.owl#genetic%20interference - rdf:type owl:NamedIndividual , - ; - :cytokine%20production%20involved%20in%20inflammatory%20response ; - :cell%20activation . - -### http://www.co-ode.org/ontologies/ont.owl#NFAT%20activation%20molecule%201 - rdf:type owl:NamedIndividual , - ; - :cytokine%20production%20involved%20in%20inflammatory%20response ; - :cytokine%20production%20involved%20in%20inflammatory%20response ; - :cytokine%20production%20involved%20in%20inflammatory%20response ; - :cytokine%20production%20involved%20in%20inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#cytokine%20production%20involved%20in%20inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :interleukin-2%20production ; - :interleukin-4%20production . -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation - rdf:type owl:NamedIndividual , - ; - :interleukin-2%20production ; - :interleukin-4%20production . - -### http://www.co-ode.org/ontologies/ont.owl#interleukin-2 - rdf:type owl:NamedIndividual , - ; - :interleukin-2%20production . - -### http://www.co-ode.org/ontologies/ont.owl#interleukin-2%20production - rdf:type owl:NamedIndividual , - ; - :Immunosuppression . - -### http://www.co-ode.org/ontologies/ont.owl#interleukin-4 - rdf:type owl:NamedIndividual , - ; - :interleukin-4%20production . - -### http://www.co-ode.org/ontologies/ont.owl#interleukin-4%20production - rdf:type owl:NamedIndividual , - ; - :Immunosuppression . - -### http://www.co-ode.org/ontologies/ont.owl#Immunosuppression - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + ; + a , . + + , ; + a , . + + a . + + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Inhibition of Calcineurin Activity Leading to Impaired T-Cell Dependent Antibody Response"^^ . diff --git a/models/AOP_155.ttl b/models/AOP_155.ttl index 3125ae44..0f173957 100644 --- a/models/AOP_155.ttl +++ b/models/AOP_155.ttl @@ -1,126 +1,83 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Cumulative fecundity and spawning"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000006481 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_2001278 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048798 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#type%20II%20iodothyronine%20deiodinase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#posterior%20chamber%20swim%20bladder - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation - rdf:type owl:NamedIndividual , - ; - :aquatic%20locomotion . - -### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Deiodinase 2 inhibition leading to increased mortality via reduced posterior swim bladder inflation"^^ . diff --git a/models/AOP_156.ttl b/models/AOP_156.ttl index 09a34535..375d70ce 100644 --- a/models/AOP_156.ttl +++ b/models/AOP_156.ttl @@ -1,126 +1,83 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, Plasma vitellogenin concentrations"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000006481 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_2001277 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048798 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#type%20II%20iodothyronine%20deiodinase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#anterior%20chamber%20swim%20bladder - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation - rdf:type owl:NamedIndividual , - ; - :aquatic%20locomotion . - -### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Deiodinase 2 inhibition leading to increased mortality via reduced anterior swim bladder inflation"^^ . diff --git a/models/AOP_157.ttl b/models/AOP_157.ttl index b961662c..a1604e02 100644 --- a/models/AOP_157.ttl +++ b/models/AOP_157.ttl @@ -1,126 +1,83 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, Vitellogenin synthesis in liver"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000006480 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_2001278 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048798 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#type%20I%20iodothyronine%20deiodinase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#posterior%20chamber%20swim%20bladder - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation - rdf:type owl:NamedIndividual , - ; - :aquatic%20locomotion . - -### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Deiodinase 1 inhibition leading to increased mortality via reduced posterior swim bladder inflation "^^ . diff --git a/models/AOP_158.ttl b/models/AOP_158.ttl index fd243ee8..1eeb8da5 100644 --- a/models/AOP_158.ttl +++ b/models/AOP_158.ttl @@ -1,126 +1,83 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, Renal pathology due to VTG deposition"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000006480 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_2001277 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048798 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#type%20I%20iodothyronine%20deiodinase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#anterior%20chamber%20swim%20bladder - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation - rdf:type owl:NamedIndividual , - ; - :aquatic%20locomotion . - -### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Deiodinase 1 inhibition leading to increased mortality via reduced anterior swim bladder inflation"^^ . diff --git a/models/AOP_159.ttl b/models/AOP_159.ttl index 15a47d36..57d48816 100644 --- a/models/AOP_159.ttl +++ b/models/AOP_159.ttl @@ -1,161 +1,107 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decrease, Population growth rate"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000016584 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004447 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_2001277 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048798 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase - rdf:type owl:NamedIndividual , - ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#anterior%20chamber%20swim%20bladder - rdf:type owl:NamedIndividual , - ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation ; - :swim%20bladder%20inflation . - -### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation - rdf:type owl:NamedIndividual , - ; - :aquatic%20locomotion . - -### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Thyroperoxidase inhibition leading to increased mortality via reduced anterior swim bladder inflation"^^ . diff --git a/models/AOP_16.ttl b/models/AOP_16.ttl index 11201038..ac24acfb 100644 --- a/models/AOP_16.ttl +++ b/models/AOP_16.ttl @@ -1,116 +1,66 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, Fushi tarazu factor-1 gene expression"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000003626 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003990 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15355 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001954 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001393 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001399 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000753 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine - rdf:type owl:NamedIndividual , - ; - :ataxia ; - :ataxia ; - :hyperactivity ; - :hyperactivity ; - :paralysis ; - :paralysis . - -### http://www.co-ode.org/ontologies/ont.owl#ataxia - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#hyperactivity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#paralysis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20distress - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20distress - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + ; + a , . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + , , ; + , , ; + a , . + + a , . + + a , . + + a , . + + a . + + ; + ; + a , . + + "development"^^ ; + a ; + "Acetylcholinesterase inhibition leading to acute mortality"^^ . diff --git a/models/AOP_160.ttl b/models/AOP_160.ttl index 406bd8fb..9f94f277 100644 --- a/models/AOP_160.ttl +++ b/models/AOP_160.ttl @@ -1,117 +1,67 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Altered, Reproductive behaviour"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17996 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0022851 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060080 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000753 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1902476 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1902710 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050805 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000079 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#paralysis - rdf:type owl:NamedIndividual , - ; - :feeding%20behavior ; - :feeding%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#chloride - rdf:type owl:NamedIndividual , - ; - :chloride%20transmembrane%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#chloride%20transmembrane%20transport - rdf:type owl:NamedIndividual , - ; - :negative%20regulation%20of%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#negative%20regulation%20of%20synaptic%20transmission - rdf:type owl:NamedIndividual , - ; - :inhibitory%20postsynaptic%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#inhibitory%20postsynaptic%20potential - rdf:type owl:NamedIndividual , - ; - :paralysis . - -### http://www.co-ode.org/ontologies/ont.owl#paralysis - rdf:type owl:NamedIndividual , - ; - :feeding%20behavior ; - :feeding%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#feeding%20behavior - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + ; + ; + a , . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Ionotropic gamma-aminobutyric acid receptor activation mediated neurotransmission inhibition leading to mortality"^^ . diff --git a/models/AOP_161.ttl b/models/AOP_161.ttl index 7318100d..d62fa5c5 100644 --- a/models/AOP_161.ttl +++ b/models/AOP_161.ttl @@ -1,123 +1,69 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Altered, Larval development"^^xsd:string . - "review"^^xsd:string . - -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1902710 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050805 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060080 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000079 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17996 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1902476 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_Q94900 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005254 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000753 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#negative%20regulation%20of%20synaptic%20transmission - rdf:type owl:NamedIndividual , - ; - :inhibitory%20postsynaptic%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#inhibitory%20postsynaptic%20potential - rdf:type owl:NamedIndividual , - ; - :paralysis . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#chloride - rdf:type owl:NamedIndividual , - ; - :chloride%20transmembrane%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#chloride%20transmembrane%20transport - rdf:type owl:NamedIndividual , - ; - :negative%20regulation%20of%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission ; - :negative%20regulation%20of%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#negative%20regulation%20of%20synaptic%20transmission - rdf:type owl:NamedIndividual , - ; - :inhibitory%20postsynaptic%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#paralysis - rdf:type owl:NamedIndividual , - ; - :feeding%20behavior ; - :feeding%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#feeding%20behavior - rdf:type owl:NamedIndividual , - ; - :mortality . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Glutamate-gated chloride channel activation leading to neurotransmission inhibition associated mortality"^^ . diff --git a/models/AOP_162.ttl b/models/AOP_162.ttl index 87dfbe6e..6fb0d546 100644 --- a/models/AOP_162.ttl +++ b/models/AOP_162.ttl @@ -1,178 +1,103 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Impaired development of, Reproductive organs"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_81567 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0002258 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006984 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001325 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008152 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#beta-1%2C3-glucuronyltransferase - rdf:type owl:NamedIndividual , - ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#glucuronosyltransferase%20activity - rdf:type owl:NamedIndividual , - ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#beta-1%2C3-glucuronyltransferase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#metabolic%20process - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :Thyroid%20stimulating%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Thyroid%20stimulating%20hormone - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :hypertrophy . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :hypertrophy . - -### http://www.co-ode.org/ontologies/ont.owl#hypertrophy - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20follicular%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Adenoma ; - :Carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + ; + a , . + + a . + + , ; + a , . + + a . + + a . + + a , . + + a , . + + a . + + a . + + ; + a , . + + , ; + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Enhanced hepatic clearance of thyroid hormones leading to thyroid follicular cell adenomas and carcinomas in the rat and mouse"^^ . diff --git a/models/AOP_163.ttl b/models/AOP_163.ttl index 8a8f835c..1ed257f3 100644 --- a/models/AOP_163.ttl +++ b/models/AOP_163.ttl @@ -1,127 +1,83 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Population growth rate"^^xsd:string . - "review"^^xsd:string . - -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000013058 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0045444 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000036194 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046903 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0008019 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010463 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_Q3U4N7 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005354 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D008080 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006394 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#eukaryotic%20protein - rdf:type owl:NamedIndividual , - ; - :secretion ; - :secretion ; - :secretion ; - :secretion . - -### http://www.co-ode.org/ontologies/ont.owl#secretion - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#mesenchymal%20cell - rdf:type owl:NamedIndividual , - ; - :mesenchymal%20cell%20proliferation ; - :mesenchymal%20cell%20proliferation ; - :mesenchymal%20cell%20proliferation ; - :mesenchymal%20cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#mesenchymal%20cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hemangiosarcoma ; - :hemangiosarcoma ; - :hemangiosarcoma ; - :hemangiosarcoma . - -### http://www.co-ode.org/ontologies/ont.owl#IGF-like%20family%20receptor%201%20%28mouse%29 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Fibrosarcoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#liposarcoma - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#hemangiosarcoma - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a , . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "PPARgamma activation leading to sarcomas in rats, mice, and hamsters"^^ . diff --git a/models/AOP_164.ttl b/models/AOP_164.ttl index 7913137a..5a5b4f35 100644 --- a/models/AOP_164.ttl +++ b/models/AOP_164.ttl @@ -1,101 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Antagonism, Estrogen receptor"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000001193 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0031698 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004941 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0044557 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000192 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0001135 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D006984 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D007889 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#beta-2%20adrenergic%20receptor - rdf:type owl:NamedIndividual , - ; - :beta-2%20adrenergic%20receptor%20binding ; - :beta-2%20adrenergic%20receptor%20binding ; - :beta-2%20adrenergic%20receptor%20binding ; - :beta-2%20adrenergic%20receptor%20binding . + a . -### http://www.co-ode.org/ontologies/ont.owl#beta-2%20adrenergic%20receptor%20binding - rdf:type owl:NamedIndividual , - ; - :beta2-adrenergic%20receptor%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#beta-2%20adrenergic%20receptor - rdf:type owl:NamedIndividual , - ; - :beta2-adrenergic%20receptor%20activity ; - :beta2-adrenergic%20receptor%20activity ; - :beta2-adrenergic%20receptor%20activity ; - :beta2-adrenergic%20receptor%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#beta2-adrenergic%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :relaxation%20of%20smooth%20muscle . + , ; + , ; + , ; + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#relaxation%20of%20smooth%20muscle - rdf:type owl:NamedIndividual , - . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#smooth%20muscle%20tissue - rdf:type owl:NamedIndividual , - ; - :hypertrophy . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#hypertrophy - rdf:type owl:NamedIndividual , - . + a , . + ; + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Beta-2 adrenergic agonist activity leading to mesovarian leiomyomas in the rat and mouse"^^ . diff --git a/models/AOP_165.ttl b/models/AOP_165.ttl index fd3c8be4..86f975f5 100644 --- a/models/AOP_165.ttl +++ b/models/AOP_165.ttl @@ -1,132 +1,85 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Vitellogenin synthesis in liver"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_23965 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030284 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D007987 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046879 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81569 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046884 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032275 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0002132 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0004911 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D016586 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#estradiol - rdf:type owl:NamedIndividual , - ; - :17beta-estradiol ; - :17beta-estradiol . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#Gonadotropin%20Releasing%20Hormone - rdf:type owl:NamedIndividual , - ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#hormone%20secretion - rdf:type owl:NamedIndividual , - ; - :luteinizing%20hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#Follicle%20stimulating%20hormone - rdf:type owl:NamedIndividual , - ; - :follicle-stimulating%20hormone%20secretion ; - :follicle-stimulating%20hormone%20secretion ; - :follicle-stimulating%20hormone%20secretion ; - :follicle-stimulating%20hormone%20secretion . + a . -### http://www.co-ode.org/ontologies/ont.owl#follicle-stimulating%20hormone%20secretion - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone - rdf:type owl:NamedIndividual , - ; - :luteinizing%20hormone%20secretion ; - :luteinizing%20hormone%20secretion ; - :luteinizing%20hormone%20secretion ; - :luteinizing%20hormone%20secretion . + a . -### http://www.co-ode.org/ontologies/ont.owl#luteinizing%20hormone%20secretion - rdf:type owl:NamedIndividual , - . + a . + a . + ; + ; + ; + ; + a , . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a , . + + ; + a , . + + a , . + + "review"^^ ; + a ; + "Antiestrogen activity leading to ovarian adenomas and granular cell tumors in the mouse"^^ . diff --git a/models/AOP_166.ttl b/models/AOP_166.ttl index 892a03fc..45415a0a 100644 --- a/models/AOP_166.ttl +++ b/models/AOP_166.ttl @@ -1,78 +1,46 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Plasma vitellogenin concentrations"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0001970 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D002779 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006629 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/PR_000005110 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000622 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#acinar%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#cholestasis - rdf:type owl:NamedIndividual , - . + a . + a . + ; + ; + ; + ; + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "PPARalpha activation leading to pancreatic acinar tumors in the rat and mouse"^^ . diff --git a/models/AOP_167.ttl b/models/AOP_167.ttl index 18910d4c..f97ea695 100644 --- a/models/AOP_167.ttl +++ b/models/AOP_167.ttl @@ -1,129 +1,85 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Vitellogenin accumulation into oocytes and oocyte growth/development"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030284 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000027727 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030520 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000014896 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000646 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D008679 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000150 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D018196 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor - rdf:type owl:NamedIndividual , - ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :intracellular%20estrogen%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor%20alpha%20complex - rdf:type owl:NamedIndividual , - ; - :intracellular%20estrogen%20receptor%20signaling%20pathway ; - :intracellular%20estrogen%20receptor%20signaling%20pathway ; - :intracellular%20estrogen%20receptor%20signaling%20pathway ; - :intracellular%20estrogen%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#intracellular%20estrogen%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#basal%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :Metaplasia ; - :Metaplasia ; - :Metaplasia ; - :Metaplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Metaplasia - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#glandular%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a , . + + "review"^^ ; + a ; + "Early-life estrogen receptor activity leading to endometrial carcinoma in the mouse."^^ . diff --git a/models/AOP_168.ttl b/models/AOP_168.ttl index a156c4f2..319749c2 100644 --- a/models/AOP_168.ttl +++ b/models/AOP_168.ttl @@ -1,118 +1,78 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Cumulative fecundity and spawning"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://id.nlm.nih.gov/mesh/D007987 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046879 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001928 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060209 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_50114 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013246 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000630 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0010307 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Gonadotropin%20Releasing%20Hormone - rdf:type owl:NamedIndividual , - ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#hormone%20secretion - rdf:type owl:NamedIndividual , - ; - :hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone - rdf:type owl:NamedIndividual , - ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#hormone%20secretion - rdf:type owl:NamedIndividual , - ; - :abnormal%20ovulation . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20ovulation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#prolactin - rdf:type owl:NamedIndividual , - ; - :mammary%20gland%20hyperplasia ; - :mammary%20gland%20hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#mammary%20gland%20hyperplasia - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + a , . + + a , . + + a , . + + ; + ; + a , . + + "review"^^ ; + a ; + "GnRH pulse disruption leading to mammary adenomas and carcinomas in the SD rat."^^ . diff --git a/models/AOP_169.ttl b/models/AOP_169.ttl index cac6ed1a..579ea1a3 100644 --- a/models/AOP_169.ttl +++ b/models/AOP_169.ttl @@ -1,128 +1,80 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "N/A, Parent compound is converted to the reactive metabolite and forms free radicals leading to oxidation of heme iron(II) in hemoglobin to iron(III)"^^xsd:string . - "review"^^xsd:string . - -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D007987 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046879 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060209 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001928 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_50114 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000439 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006984 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/HP_0002893 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Gonadotropin%20Releasing%20Hormone - rdf:type owl:NamedIndividual , - ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#hormone%20secretion - rdf:type owl:NamedIndividual , - ; - :hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone - rdf:type owl:NamedIndividual , - ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion ; - :hormone%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#hormone%20secretion - rdf:type owl:NamedIndividual , - ; - :abnormal%20ovulation . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20ovulation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen - rdf:type owl:NamedIndividual , - ; - :hyperplasia ; - :hypertrophy . - -### http://www.co-ode.org/ontologies/ont.owl#prolactin%20secreting%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#prolactin%20secreting%20cell - rdf:type owl:NamedIndividual , - ; - :hypertrophy . + a . -### http://www.co-ode.org/ontologies/ont.owl#hypertrophy - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a , . + + a . + + ; + ; + a , . + + a . + + a , . + + , ; + a , . + + a . + + a . + + , ; + a , . + + "review"^^ ; + a ; + "GnRH pulse disruption leading to pituitary adenomas and carcinomas in the SD rat."^^ . diff --git a/models/AOP_17.ttl b/models/AOP_17.ttl index 5e2787f5..3080e03e 100644 --- a/models/AOP_17.ttl +++ b/models/AOP_17.ttl @@ -1,118 +1,58 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decrease, Circulating crustacean cardioactive peptide"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000129 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001847 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000127 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0099536 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002263 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002526 - rdf:type owl:Class . + a . + ; + ; + a , . + ; + ; + a , . -################################################################# -# Individuals -################################################################# + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . + a . -### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . + a . -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death . + a , . -### http://www.co-ode.org/ontologies/ont.owl#astrocyte - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . + a . -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . + a . -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins involved in protection against oxidative stress during brain development leads to impairment of learning and memory"^^ . diff --git a/models/AOP_170.ttl b/models/AOP_170.ttl index dd13cb60..a3ccd04f 100644 --- a/models/AOP_170.ttl +++ b/models/AOP_170.ttl @@ -1,71 +1,41 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Altered regulation, Alpha hemoglobin"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CL_0000700 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001963 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000013246 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0070459 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0001911 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0010307 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#mammary%20gland - rdf:type owl:NamedIndividual , - ; - :hyperplasia . + a . -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - . + a . + a . + ; + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Anti-dopaminergic activity leading to mammary adenomas and carcinomas in the SD rat"^^ . diff --git a/models/AOP_171.ttl b/models/AOP_171.ttl index 0ccfaf5e..ea3ba5aa 100644 --- a/models/AOP_171.ttl +++ b/models/AOP_171.ttl @@ -1,95 +1,57 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Propagation, Oxidative stress"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/UBERON_0000977 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006954 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000036194 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046903 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/UBERON_0001136 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D008654 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#pleura - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress . + a . -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#mesothelium - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - . + a . + ; + ; + ; + ; + a , . + ; + ; + ; + ; + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Chronic cytotoxicity of the serous membrane leading to pleural/peritoneal mesotheliomas in the rat."^^ . diff --git a/models/AOP_175.ttl b/models/AOP_175.ttl index d8b28a7a..62ccb391 100644 --- a/models/AOP_175.ttl +++ b/models/AOP_175.ttl @@ -1,91 +1,57 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, RBC congestion in liver"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000016584 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004447 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase - rdf:type owl:NamedIndividual , - ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + a . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . + ; + ; + a , . + a . + a . -################################################################# -# Object Statements -################################################################# + ; + a , . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Thyroperoxidase inhibition leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_176.ttl b/models/AOP_176.ttl index 5f1051fe..763275ba 100644 --- a/models/AOP_176.ttl +++ b/models/AOP_176.ttl @@ -1,107 +1,67 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, Liver and splenic hemosiderosis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000015171 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008507 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_16382 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0015705 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#sodium/iodide%20cotransporter - rdf:type owl:NamedIndividual , - ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#sodium%3Aiodide%20symporter%20activity - rdf:type owl:NamedIndividual , - ; - :iodide%20transport . + a . -### http://www.co-ode.org/ontologies/ont.owl#iodide - rdf:type owl:NamedIndividual , - ; - :iodide%20transport . + a , . -### http://www.co-ode.org/ontologies/ont.owl#iodide%20transport - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . + ; + ; + a , . + a . + a . -################################################################# -# Object Statements -################################################################# + ; + ; + ; + ; + a , . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + ; + a , . + + "review"^^ ; + a ; + "Sodium Iodide Symporter (NIS) Inhibition leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_177.ttl b/models/AOP_177.ttl index 038c2370..09b37e56 100644 --- a/models/AOP_177.ttl +++ b/models/AOP_177.ttl @@ -1,146 +1,86 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Methemoglobinemia, decreased hemoglobin, hematocrit, red blood cell number"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_15553 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002113 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D007511 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0004154 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26216 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000013427 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004666 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D001145 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_27226 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20F2alpha - rdf:type owl:NamedIndividual , - ; - :ischemia . - -### http://www.co-ode.org/ontologies/ont.owl#kidney - rdf:type owl:NamedIndividual , - ; - :ischemia . - -### http://www.co-ode.org/ontologies/ont.owl#ischemia - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress . - -### http://www.co-ode.org/ontologies/ont.owl#potassium%20atom - rdf:type owl:NamedIndividual , - ; - :Arrhythmias%2C%20Cardiac ; - :Arrhythmias%2C%20Cardiac . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20F2alpha - rdf:type owl:NamedIndividual , - ; - :ischemia . - -### http://www.co-ode.org/ontologies/ont.owl#Arrhythmias%2C%20Cardiac - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :renal%20tubular%20necrosis . - -### http://www.co-ode.org/ontologies/ont.owl#renal%20tubular%20necrosis - rdf:type owl:NamedIndividual , - ; - :uric%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#uric%20acid - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress ; - :oxidative%20stress . - -### http://www.co-ode.org/ontologies/ont.owl#uric%20acid - rdf:type owl:NamedIndividual , - ; - :renal%20tubular%20necrosis ; - :renal%20tubular%20necrosis . + a . -### http://www.co-ode.org/ontologies/ont.owl#renal%20tubular%20necrosis - rdf:type owl:NamedIndividual , - ; - :uric%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :renal%20tubular%20necrosis . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + ; + a , . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + , ; + , ; + a , . + + a . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Cyclooxygenase 1 (COX1) inhibition leading to renal failure and mortality"^^ . diff --git a/models/AOP_178.ttl b/models/AOP_178.ttl index c7d418c4..bde13bee 100644 --- a/models/AOP_178.ttl +++ b/models/AOP_178.ttl @@ -1,60 +1,30 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Cyanosis occurs"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . + a . -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Nicotinic acetylcholine receptor activation contributes to mitochondrial dysfunction and leads to colony loss/failure"^^ . diff --git a/models/AOP_179.ttl b/models/AOP_179.ttl index 4432b7be..c07d9dbc 100644 --- a/models/AOP_179.ttl +++ b/models/AOP_179.ttl @@ -1,50 +1,18 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Production, Critical Metabolites (CGA 330050 and CGA 265307)"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D019562 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + ; + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Viral%20load - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Varroa mite infestation increases virus levels leading to colony loss/failure"^^ . diff --git a/models/AOP_18.ttl b/models/AOP_18.ttl index 77b59af7..323364d7 100644 --- a/models/AOP_18.ttl +++ b/models/AOP_18.ttl @@ -1,131 +1,75 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Ecdysis motoneuron bursts"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000015715 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16113 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006839 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0061370 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000016757 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0003135 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#STAR - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :mitochondrial%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol - rdf:type owl:NamedIndividual , - ; - :mitochondrial%20transport ; - :mitochondrial%20transport ; - :mitochondrial%20transport ; - :mitochondrial%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrial%20transport - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :testosterone ; - :testosterone ; - :testosterone ; - :testosterone . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol - rdf:type owl:NamedIndividual , - ; - :mitochondrial%20transport ; - :mitochondrial%20transport ; - :mitochondrial%20transport ; - :mitochondrial%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrial%20transport - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - . + a . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "PPARĪ± activation in utero leading to impaired fertility in males"^^ . diff --git a/models/AOP_180.ttl b/models/AOP_180.ttl index 9fe90d54..6651a391 100644 --- a/models/AOP_180.ttl +++ b/models/AOP_180.ttl @@ -1,51 +1,20 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Induction, Liver ā€œDysfunctionalā€ Changes by CGA 330050"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + ; + a , . + a . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Varroa mite infestation contributes to abnormal foraging leading to colony loss/failure"^^ . diff --git a/models/AOP_181.ttl b/models/AOP_181.ttl index 3f821a14..4582420a 100644 --- a/models/AOP_181.ttl +++ b/models/AOP_181.ttl @@ -1,42 +1,13 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, Inducible Nitric Oxide Synthase by Metabolite CGA 265307"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + a . + ; + a , . - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Weather event contributes to colony loss/failure"^^ . diff --git a/models/AOP_182.ttl b/models/AOP_182.ttl index 929d66d4..0f13c14b 100644 --- a/models/AOP_182.ttl +++ b/models/AOP_182.ttl @@ -1,51 +1,20 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Induction, Sustained Hepatotoxicity"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + ; + a , . + a . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Weather event contributes abnormal foraging leading to colony loss/failure"^^ . diff --git a/models/AOP_183.ttl b/models/AOP_183.ttl index e08c4ec0..63846d76 100644 --- a/models/AOP_183.ttl +++ b/models/AOP_183.ttl @@ -1,70 +1,35 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Induction, Sustained Cell Proliferation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/MP_0004889 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D013312 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#increased%20energy%20expenditure - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior ; - :foraging%20behavior . + a . -### http://www.co-ode.org/ontologies/ont.owl#Stress%2C%20Physiological - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . + a . -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Nosema infection increases energetic demands leading to colony loss/failure"^^ . diff --git a/models/AOP_184.ttl b/models/AOP_184.ttl index 38081abf..33ba9db1 100644 --- a/models/AOP_184.ttl +++ b/models/AOP_184.ttl @@ -1,50 +1,18 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Formation, Liver tumor"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D012380 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + a . + ; + a , . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#role - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Nosema infection causes abnormal role change that leads to colony loss/failure"^^ . diff --git a/models/AOP_185.ttl b/models/AOP_185.ttl index 1ea2ba27..010c6413 100644 --- a/models/AOP_185.ttl +++ b/models/AOP_185.ttl @@ -1,42 +1,13 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, 5HT2c"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + a . + ; + a , . - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Queen egg-laying decrease leads to colony loss/failure"^^ . diff --git a/models/AOP_186.ttl b/models/AOP_186.ttl index 8f40c948..89a1dda4 100644 --- a/models/AOP_186.ttl +++ b/models/AOP_186.ttl @@ -1,78 +1,45 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Kidney Failure"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . + ; + ; + a , . -### http://purl.obolibrary.org/obo/MP_0004154 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26216 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D001145 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress ; - :oxidative%20stress . + a . -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#potassium%20atom - rdf:type owl:NamedIndividual , - ; - :Arrhythmias%2C%20Cardiac ; - :Arrhythmias%2C%20Cardiac . + a . -### http://www.co-ode.org/ontologies/ont.owl#Arrhythmias%2C%20Cardiac - rdf:type owl:NamedIndividual , - ; - :mortality . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . + a , . + a , . + ; + ; + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "unknown MIE leading to renal failure and mortality"^^ . diff --git a/models/AOP_187.ttl b/models/AOP_187.ttl index 34217c29..a1960386 100644 --- a/models/AOP_187.ttl +++ b/models/AOP_187.ttl @@ -1,220 +1,134 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Unknown"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0007599 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001914 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042060 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000007299 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MI_1139 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_P70375 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_P16294 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_O88947 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_33284 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006810 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1990748 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001577 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D001779 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_28384 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042373 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D064417 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003031 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0010128 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0000062 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_1000152 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0017077 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0000066 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0002049 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D061205 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000030444 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0043687 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_P19788 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#hemostasis - rdf:type owl:NamedIndividual , - ; - :hemorrhage ; - :wound%20healing . + a . -### http://www.co-ode.org/ontologies/ont.owl#prothrombin - rdf:type owl:NamedIndividual , - ; - :carboxylation%20reaction . + a . -### http://www.co-ode.org/ontologies/ont.owl#carboxylation%20reaction - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#coagulation%20factor%20VII%20%28mouse%29 - rdf:type owl:NamedIndividual , - ; - :carboxylation%20reaction . + a . -### http://www.co-ode.org/ontologies/ont.owl#carboxylation%20reaction - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#coagulation%20factor%20IX%20%28mouse%29 - rdf:type owl:NamedIndividual , - ; - :carboxylation%20reaction . + a . -### http://www.co-ode.org/ontologies/ont.owl#carboxylation%20reaction - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#coagulation%20factor%20X%20%28mouse%29 - rdf:type owl:NamedIndividual , - ; - :carboxylation%20reaction . + a , . -### http://www.co-ode.org/ontologies/ont.owl#carboxylation%20reaction - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#hemorrhage - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :cellular%20detoxification ; - :cellular%20detoxification ; - :anemia ; - :anemia . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#wound%20healing - rdf:type owl:NamedIndividual , - ; - :transport ; - :cellular%20detoxification ; - :anemia . - -### http://www.co-ode.org/ontologies/ont.owl#nutrient - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :transport ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#transport - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cellular%20detoxification - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#anemia - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + ; + a , . + + ; + a , . + + ; + ; + , ; + , ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a , . + + , ; + ; + a , . + + "review"^^ ; + a ; + "Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage"^^ . diff --git a/models/AOP_188.ttl b/models/AOP_188.ttl index 3a0ddeac..6aa9e5b4 100644 --- a/models/AOP_188.ttl +++ b/models/AOP_188.ttl @@ -1,107 +1,67 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, LXR"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_Q6PHW0 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_16382 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0015705 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#iodotyrosine%20deiodinase%201%20%28human%29 - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :iodide%20transport . + a . -### http://www.co-ode.org/ontologies/ont.owl#iodide - rdf:type owl:NamedIndividual , - ; - :iodide%20transport . + a . -### http://www.co-ode.org/ontologies/ont.owl#iodide%20transport - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + a . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . + ; + a , . + ; + ; + ; + ; + a , . + ; + a , . -################################################################# -# Object Statements -################################################################# + ; + a , . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + ; + ; + a , . + + "review"^^ ; + a ; + "Iodotyrosine deiodinase (IYD) inhibition leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_189.ttl b/models/AOP_189.ttl index 68337341..c49bb719 100644 --- a/models/AOP_189.ttl +++ b/models/AOP_189.ttl @@ -1,109 +1,58 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Up Regulation, CD36"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000006480 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_18258 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#type%20I%20iodothyronine%20deiodinase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5-triiodo-L-thyronine - rdf:type owl:NamedIndividual , - ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5-triiodo-L-thyronine - rdf:type owl:NamedIndividual , - ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis ; - :metamorphosis . - -### http://www.co-ode.org/ontologies/ont.owl#metamorphosis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#metamorphosis - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Type I iodothyronine deiodinase (DIO1) inhibition leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_19.ttl b/models/AOP_19.ttl index 1d32420e..e4747126 100644 --- a/models/AOP_19.ttl +++ b/models/AOP_19.ttl @@ -1,150 +1,75 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Excitatory postsynaptic potential"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004882 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1990909 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0016055 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0003135 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032502 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#Wnt%20signalosome - rdf:type owl:NamedIndividual , - ; - :Wnt%20signaling%20pathway ; - :Wnt%20signaling%20pathway ; - :Wnt%20signaling%20pathway ; - :Wnt%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#Wnt%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :developmental%20process . - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - ; - :developmental%20process . - -### http://www.co-ode.org/ontologies/ont.owl#Wnt%20signalosome - rdf:type owl:NamedIndividual , - ; - :Wnt%20signaling%20pathway ; - :Wnt%20signaling%20pathway ; - :Wnt%20signaling%20pathway ; - :Wnt%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#Wnt%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :developmental%20process . - -### http://www.co-ode.org/ontologies/ont.owl#male%20reproductive%20organ - rdf:type owl:NamedIndividual , - ; - :developmental%20process ; - :developmental%20process ; - :developmental%20process ; - :developmental%20process . - -### http://www.co-ode.org/ontologies/ont.owl#developmental%20process - rdf:type owl:NamedIndividual , - ; - :fertility ; - :fertility ; - :fertility ; - :fertility . - -### http://www.co-ode.org/ontologies/ont.owl#male%20reproductive%20organ - rdf:type owl:NamedIndividual , - ; - :developmental%20process ; - :developmental%20process ; - :developmental%20process ; - :developmental%20process . - -### http://www.co-ode.org/ontologies/ont.owl#developmental%20process - rdf:type owl:NamedIndividual , - ; - :fertility ; - :fertility ; - :fertility ; - :fertility . - -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Androgen receptor antagonism leading to adverse effects in the male foetus (mammals)"^^ . diff --git a/models/AOP_190.ttl b/models/AOP_190.ttl index 30d17891..09c7c20f 100644 --- a/models/AOP_190.ttl +++ b/models/AOP_190.ttl @@ -1,84 +1,48 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, FA Influx"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000006481 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_18258 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81567 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#type%20II%20iodothyronine%20deiodinase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5-triiodo-L-thyronine - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5-triiodo-L-thyronine - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Thyroid%20stimulating%20hormone - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "Type II iodothyronine deiodinase (DIO2) inhibition leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_191.ttl b/models/AOP_191.ttl index f2e4fc67..094841b6 100644 --- a/models/AOP_191.ttl +++ b/models/AOP_191.ttl @@ -1,77 +1,46 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Activation, ChREBP"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000006482 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_18258 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#type%20III%20iodothyronine%20deiodinase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine ; - :3%2C3%27%2C5-triiodo-L-thyronine . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5-triiodo-L-thyronine - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#metamorphosis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#metamorphosis - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + a , . + + a . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "Type III iodotyrosine deiodinase (DIO3) inhibition leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_192.ttl b/models/AOP_192.ttl index 3a5cd23f..db848de0 100644 --- a/models/AOP_192.ttl +++ b/models/AOP_192.ttl @@ -1,91 +1,57 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, SREBP-1c"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000015039 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#pendrin - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . + a . -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + a . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + a . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . + ; + a , . + ; + ; + a , . + a . -################################################################# -# Object Statements -################################################################# + ; + ; + ; + ; + a , . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + ; + a , . + + "review"^^ ; + a ; + "Pendrin inhibition leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_193.ttl b/models/AOP_193.ttl index 861fd1c3..9b0c8243 100644 --- a/models/AOP_193.ttl +++ b/models/AOP_193.ttl @@ -1,91 +1,57 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, FAS"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000006727 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#dual%20oxidase%201 - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + a . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . + a . -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . + a , . -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . + ; + a , . + ; + a , . + ; + ; + a , . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Dual oxidase (DUOX) inhibition leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_194.ttl b/models/AOP_194.ttl index 851c8b4d..52aa10b1 100644 --- a/models/AOP_194.ttl +++ b/models/AOP_194.ttl @@ -1,169 +1,87 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Activation, SCD-1"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006810 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001325 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008152 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#protein - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :glucuronosyltransferase%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :transport ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#transport - rdf:type owl:NamedIndividual , - ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#beta-1%2C3-glucuronyltransferase - rdf:type owl:NamedIndividual , - ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#glucuronosyltransferase%20activity - rdf:type owl:NamedIndividual , - ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#beta-1%2C3-glucuronyltransferase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#metabolic%20process - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#metabolic%20process - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Hepatic nuclear receptor activation leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_195.ttl b/models/AOP_195.ttl index dfecfe57..4426a92f 100644 --- a/models/AOP_195.ttl +++ b/models/AOP_195.ttl @@ -1,163 +1,92 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Synthesis, De Novo FA"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000015189 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0098810 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051610 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001820 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000300 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048469 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/C82476 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0003978 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050881 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0022414 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#sodium-dependent%20serotonin%20transporter - rdf:type owl:NamedIndividual , - ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#serotonin%20secretion - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#gamete - rdf:type owl:NamedIndividual , - ; - :cell%20maturation ; - :cell%20maturation ; - :cell%20maturation ; - :cell%20maturation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20maturation - rdf:type owl:NamedIndividual , - ; - :spawning ; - :spawning ; - :spawning ; - :spawning . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#sodium-dependent%20serotonin%20transporter - rdf:type owl:NamedIndividual , - ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#serotonin%20secretion - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#valve - rdf:type owl:NamedIndividual , - ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement . - -### http://www.co-ode.org/ontologies/ont.owl#musculoskeletal%20movement - rdf:type owl:NamedIndividual , - ; - :spawning ; - :spawning ; - :spawning ; - :spawning . - -### http://www.co-ode.org/ontologies/ont.owl#spawning - rdf:type owl:NamedIndividual , - ; - :reproductive%20process ; - :reproductive%20process ; - :reproductive%20process ; - :reproductive%20process . - -### http://www.co-ode.org/ontologies/ont.owl#spawning - rdf:type owl:NamedIndividual , - ; - :reproductive%20process ; - :reproductive%20process ; - :reproductive%20process ; - :reproductive%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20process - rdf:type owl:NamedIndividual , - ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms . - -### http://www.co-ode.org/ontologies/ont.owl#spawning - rdf:type owl:NamedIndividual , - ; - :reproductive%20process ; - :reproductive%20process ; - :reproductive%20process ; - :reproductive%20process . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "5-hydroxytryptamine transporter (5-HTT) inhibition leading to population increase"^^ . diff --git a/models/AOP_196.ttl b/models/AOP_196.ttl index 9c90c651..f5e91363 100644 --- a/models/AOP_196.ttl +++ b/models/AOP_196.ttl @@ -1,337 +1,155 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Accumulation, Triglyceride"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000001065 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006816 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0001759 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0043179 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_80308 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005184 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0001645 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060004 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D003371 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D012130 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D004417 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0001004 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006954 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_80337 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D012912 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_80311 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#transient%20receptor%20potential%20cation%20channel%20TRPV1 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport - rdf:type owl:NamedIndividual , - ; - :rhythmic%20excitation . - -### http://www.co-ode.org/ontologies/ont.owl#vagus%20nerve - rdf:type owl:NamedIndividual , - ; - :rhythmic%20excitation ; - :rhythmic%20excitation ; - :rhythmic%20excitation ; - :rhythmic%20excitation . - -### http://www.co-ode.org/ontologies/ont.owl#rhythmic%20excitation - rdf:type owl:NamedIndividual , - ; - :reflex . - -### http://www.co-ode.org/ontologies/ont.owl#Substance%20P - rdf:type owl:NamedIndividual , - ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#neuropeptide%20hormone%20activity - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response ; - :cough ; - :cough ; - :cough ; - :cough . - -### http://www.co-ode.org/ontologies/ont.owl#Calcitonin%20gene-related%20peptide%201 - rdf:type owl:NamedIndividual , - ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#neuropeptide%20hormone%20activity - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response ; - :cough ; - :cough ; - :cough ; - :cough . - -### http://www.co-ode.org/ontologies/ont.owl#Neurokinin%20A - rdf:type owl:NamedIndividual , - ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity ; - :neuropeptide%20hormone%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#neuropeptide%20hormone%20activity - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response ; - :cough ; - :cough ; - :cough ; - :cough . - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20system - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response ; - :inflammatory%20response ; - :inflammatory%20response ; - :inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :reflex ; - :cough ; - :cough ; - :cough ; - :cough ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Dyspnea ; - :Dyspnea ; - :Dyspnea ; - :Dyspnea . - -### http://www.co-ode.org/ontologies/ont.owl#cough - rdf:type owl:NamedIndividual , - ; - :reflex ; - :reflex ; - :reflex ; - :reflex ; - :cough ; - :cough ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Dyspnea ; - :Dyspnea . - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20system - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response ; - :inflammatory%20response ; - :inflammatory%20response ; - :inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :reflex ; - :cough ; - :cough ; - :cough ; - :cough ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Dyspnea ; - :Dyspnea ; - :Dyspnea ; - :Dyspnea . - -### http://www.co-ode.org/ontologies/ont.owl#cough - rdf:type owl:NamedIndividual , - ; - :reflex ; - :reflex ; - :reflex ; - :reflex ; - :cough ; - :cough ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Dyspnea ; - :Dyspnea . - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20system - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response ; - :inflammatory%20response ; - :inflammatory%20response ; - :inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :reflex ; - :cough ; - :cough ; - :cough ; - :cough ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Dyspnea ; - :Dyspnea ; - :Dyspnea ; - :Dyspnea . - -### http://www.co-ode.org/ontologies/ont.owl#cough - rdf:type owl:NamedIndividual , - ; - :reflex ; - :reflex ; - :reflex ; - :reflex ; - :cough ; - :cough ; - :Respiratory%20Hypersensitivity ; - :Respiratory%20Hypersensitivity ; - :Dyspnea ; - :Dyspnea . - -### http://www.co-ode.org/ontologies/ont.owl#trigeminal%20nerve - rdf:type owl:NamedIndividual , - ; - :reflex ; - :reflex ; - :reflex ; - :reflex . - -### http://www.co-ode.org/ontologies/ont.owl#reflex - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cough - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Respiratory%20Hypersensitivity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Dyspnea - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#sneezing - rdf:type owl:NamedIndividual , - ; - :reflex ; - :reflex ; - :reflex ; - :reflex . - -### http://www.co-ode.org/ontologies/ont.owl#reflex - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + , , ; + , , ; + a , . + + a , . + + ; + , , ; + , , ; + , , ; + , , ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + ; + a , . + + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation"^^ . diff --git a/models/AOP_197.ttl b/models/AOP_197.ttl index 1001db85..a8fb4662 100644 --- a/models/AOP_197.ttl +++ b/models/AOP_197.ttl @@ -1,103 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Damaging, Mitochondria"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000002095 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019871 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_29101 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006810 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16865 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20protein%20type%201%20subunit%20alpha - rdf:type owl:NamedIndividual , - ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20inhibitor%20activity - rdf:type owl:NamedIndividual , - ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20protein%20type%201%20subunit%20alpha - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#sodium%281%2B%29 - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :transport ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#transport - rdf:type owl:NamedIndividual , - ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :transport ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#transport - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Sodium channel (Nav1.1) inhibition leading to population decline"^^ . diff --git a/models/AOP_200.ttl b/models/AOP_200.ttl index f14fa406..b9fd5458 100644 --- a/models/AOP_200.ttl +++ b/models/AOP_200.ttl @@ -1,276 +1,140 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Accumulation, Biological membranes"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030331 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000016261 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0001935 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0043542 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D001943 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0031012 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000066 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001775 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042116 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001525 - rdf:type owl:Class . + , ; + a , . -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000000001 - rdf:type owl:Class . + ; + ; + ; + ; + a , . -### http://purl.obolibrary.org/obo/GO_0006412 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048870 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019932 - rdf:type owl:Class . + , ; + , ; + , ; + , ; + a , . + a . - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :second-messenger-mediated%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor%20binding - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Breast%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Breast%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#serotransferrin - rdf:type owl:NamedIndividual , - ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor%20binding - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Breast%20Neoplasms - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#angiogenesis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#angiogenesis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#serotransferrin - rdf:type owl:NamedIndividual , - ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding ; - :estrogen%20receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor%20binding - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :translation . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :translation . - -### http://www.co-ode.org/ontologies/ont.owl#protein - rdf:type owl:NamedIndividual , - ; - :translation ; - :translation ; - :translation ; - :translation . - -### http://www.co-ode.org/ontologies/ont.owl#translation - rdf:type owl:NamedIndividual , - ; - :cell%20motility . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :deoxyribonucleic%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :translation . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :translation . - -### http://www.co-ode.org/ontologies/ont.owl#endothelial%20cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :angiogenesis . - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20motility - rdf:type owl:NamedIndividual , - ; - :epithelial%20cell ; - :epithelial%20cell ; - :epithelial%20cell ; - :epithelial%20cell . - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20cell - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#second-messenger-mediated%20signaling - rdf:type owl:NamedIndividual , - ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Estrogen receptor activation leading to breast cancer "^^ . diff --git a/models/AOP_201.ttl b/models/AOP_201.ttl index 7ae096ae..b4f43c98 100644 --- a/models/AOP_201.ttl +++ b/models/AOP_201.ttl @@ -1,122 +1,88 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Disruption, Membrane integrity"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_24943 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_P23023 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_1000189 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0003101 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0003135 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D020387 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#juvenile%20hormone - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20doublesex%20%28fruit%20fly%29 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :male%20reproductive%20organ ; - :male%20reproductive%20organ ; - :male%20reproductive%20organ ; - :male%20reproductive%20organ . - -### http://www.co-ode.org/ontologies/ont.owl#male%20reproductive%20organ - rdf:type owl:NamedIndividual , - ; - :offspring%20quantity ; - :offspring%20quantity ; - :male%20organism ; - :male%20organism . - -### http://www.co-ode.org/ontologies/ont.owl#offspring%20quantity - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#male%20organism - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Juvenile hormone receptor agonism leading to male offspring induction associated population decline"^^ . diff --git a/models/AOP_202.ttl b/models/AOP_202.ttl index f2052e04..a7bda471 100644 --- a/models/AOP_202.ttl +++ b/models/AOP_202.ttl @@ -1,43 +1,14 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, PPAR-alpha activation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0061505 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D014178 - rdf:type owl:Class . + a , . + a , . - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20topoisomerase%20II%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Translocation%2C%20Genetic - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - + "development"^^ ; + a ; + "Inhibitor binding to topoisomerase II leading to infant leukaemia"^^ . diff --git a/models/AOP_203.ttl b/models/AOP_203.ttl index b0fa4d58..7eba006d 100644 --- a/models/AOP_203.ttl +++ b/models/AOP_203.ttl @@ -1,79 +1,46 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, PPAR-beta activation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000015189 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0098810 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0051610 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0003978 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0050881 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001820 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#valve - rdf:type owl:NamedIndividual , - ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement . + a . -### http://www.co-ode.org/ontologies/ont.owl#musculoskeletal%20movement - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#sodium-dependent%20serotonin%20transporter - rdf:type owl:NamedIndividual , - ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion . + a , . -### http://www.co-ode.org/ontologies/ont.owl#serotonin%20secretion - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . + ; + ; + ; + ; + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "5-hydroxytryptamine transporter inhibition leading to decreased reproductive success and population decline"^^ . diff --git a/models/AOP_204.ttl b/models/AOP_204.ttl index a2b6d35c..efbb03e2 100644 --- a/models/AOP_204.ttl +++ b/models/AOP_204.ttl @@ -1,98 +1,64 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased, PPAR-gamma activation"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000015189 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0098810 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051610 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0003978 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050881 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0022414 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001820 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20process - rdf:type owl:NamedIndividual , - ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms . - -### http://www.co-ode.org/ontologies/ont.owl#sodium-dependent%20serotonin%20transporter - rdf:type owl:NamedIndividual , - ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#serotonin%20secretion - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#valve - rdf:type owl:NamedIndividual , - ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement . - -### http://www.co-ode.org/ontologies/ont.owl#musculoskeletal%20movement - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "5-hydroxytryptamine transporter inhibition leading to increased reproductive success and population increase"^^ . diff --git a/models/AOP_205.ttl b/models/AOP_205.ttl index e83653d4..451c5d04 100644 --- a/models/AOP_205.ttl +++ b/models/AOP_205.ttl @@ -1,64 +1,36 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Accumulation, Fatty acid"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0016043 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MI_0613 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007009 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0070265 - rdf:type owl:Class . + a . + a , . + ; + ; + ; + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :apoptotic%20process ; - :apoptotic%20process ; - :apoptotic%20process ; - :apoptotic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - . + a . + a . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "AOP from chemical insult to cell death"^^ . diff --git a/models/AOP_206.ttl b/models/AOP_206.ttl index 2264ef1e..7612e696 100644 --- a/models/AOP_206.ttl +++ b/models/AOP_206.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, HSD17B10 expression"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0006954 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Peroxisome proliferator-activated receptors Ī³ inactivation leading to lung fibrosis"^^ . diff --git a/models/AOP_207.ttl b/models/AOP_207.ttl index 9864474a..8c442218 100644 --- a/models/AOP_207.ttl +++ b/models/AOP_207.ttl @@ -1,174 +1,100 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased, Mitochondrial fatty acid beta-oxidation"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://id.nlm.nih.gov/mesh/D019255 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000003 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009058 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000003106 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_G5EGD2 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0061726 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#NADPH%20Oxidase - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#map%20kinase%20p38 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - ; - :apoptotic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :mitochondrion%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion%20disassembly - rdf:type owl:NamedIndividual , - ; - :apoptotic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201%20%28Caenorhabditis%20elegans%29 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :apoptotic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#reproduction - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + , , ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + "review"^^ ; + a ; + "NADPH oxidase and P38 MAPK activation leading to reproductive failure in Caenorhabditis elegans"^^ . diff --git a/models/AOP_208.ttl b/models/AOP_208.ttl index abf4ec3a..c9ae71c8 100644 --- a/models/AOP_208.ttl +++ b/models/AOP_208.ttl @@ -1,92 +1,49 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased, 3-hydroxyacyl-CoA dehydrogenase type-2 activity"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000025748 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001933 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000000046 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000003 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Janus%20kinase - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signal%20transducer%20and%20transcription%20activator%20STAT - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#TGF-beta - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#reproduction - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Janus kinase (JAK)/Signal transducer and activator of transcription (STAT) and Transforming growth factor (TGF)-beta pathways activation leading to reproductive failure"^^ . diff --git a/models/AOP_209.ttl b/models/AOP_209.ttl index 736d0ccc..516ef3a4 100644 --- a/models/AOP_209.ttl +++ b/models/AOP_209.ttl @@ -1,141 +1,88 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increased, Liver Steatosis"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000021564 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_27208 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006636 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/PR_000008293 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004363 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000029945 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004364 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16856 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006750 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000008774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003857 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16113 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#sterol%20regulatory%20element-binding%20protein%202%20proteolytic%20cleavage%20product - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :unsaturated%20fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#unsaturated%20fatty%20acid - rdf:type owl:NamedIndividual , - ; - :unsaturated%20fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#unsaturated%20fatty%20acid%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :cholesterol ; - :cholesterol ; - :cholesterol ; - :cholesterol . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#glutathione - rdf:type owl:NamedIndividual , - ; - :glutathione%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#glutathione%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#3-hydroxyacyl-CoA%20dehydrogenase%20type-2 - rdf:type owl:NamedIndividual , - ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#3-hydroxyacyl-CoA%20dehydrogenase%20activity - rdf:type owl:NamedIndividual , - ; - :cholesterol ; - :cholesterol ; - :cholesterol ; - :cholesterol . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#glutathione - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "Perturbation of cholesterol and glutathione homeostasis leading to hepatotoxicity: Integrated multi-OMICS approach for building AOP "^^ . diff --git a/models/AOP_21.ttl b/models/AOP_21.ttl index c67353a4..21b448fe 100644 --- a/models/AOP_21.ttl +++ b/models/AOP_21.ttl @@ -1,140 +1,86 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased, PPARalpha transactivation of gene expression"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046983 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004303 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001544 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0004535 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072358 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013428 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0008762 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%202 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :abnormal%20cardiovascular%20system%20physiology ; - :cardiovascular%20system%20development . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20cardiovascular%20system%20physiology - rdf:type owl:NamedIndividual , - ; - :embryonic%20lethality ; - :embryonic%20lethality ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#cardiovascular%20system - rdf:type owl:NamedIndividual , - ; - :cardiovascular%20system%20development ; - :cardiovascular%20system%20development ; - :cardiovascular%20system%20development ; - :cardiovascular%20system%20development . - -### http://www.co-ode.org/ontologies/ont.owl#cardiovascular%20system%20development - rdf:type owl:NamedIndividual , - ; - :embryonic%20lethality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#embryonic%20lethality - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to early life stage mortality, via increased COX-2"^^ . diff --git a/models/AOP_210.ttl b/models/AOP_210.ttl index 61a331c9..93ee3656 100644 --- a/models/AOP_210.ttl +++ b/models/AOP_210.ttl @@ -1,111 +1,64 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Activation, PPARĪ±"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D048031 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_O16850 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1990909 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009790 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000003 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#JNK%20Mitogen-Activated%20Protein%20Kinases - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#forkhead%20box%20protein%20O%20%28Caenorhabditis%20elegans%29 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#Wnt%20signalosome - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :embryo%20development . - -### http://www.co-ode.org/ontologies/ont.owl#embryo%20development - rdf:type owl:NamedIndividual , - ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#reproduction - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + a , . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Activation of c-Jun N-terminal kinase (JNK) and Forkhead box O (FOXO) and reduction of WNT pathways leading to reproductive failure: Integrated multi-OMICS approach for AOP building"^^ . diff --git a/models/AOP_212.ttl b/models/AOP_212.ttl index 457153cd..31662bbe 100644 --- a/models/AOP_212.ttl +++ b/models/AOP_212.ttl @@ -1,133 +1,91 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, cell proliferation (hepatocytes)"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000008478 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004857 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15358 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0031399 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000029191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051726 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/FMA_7210 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/HP_0000029 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000017 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#histone%20deacetylase%201 - rdf:type owl:NamedIndividual , - ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#enzyme%20inhibitor%20activity - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20protein%20modification%20process . - -### http://www.co-ode.org/ontologies/ont.owl#histone - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20protein%20modification%20process ; - :regulation%20of%20protein%20modification%20process ; - :regulation%20of%20protein%20modification%20process ; - :regulation%20of%20protein%20modification%20process . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20protein%20modification%20process - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20cell%20cycle . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20cycle-related%20cyclin - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20cell%20cycle ; - :regulation%20of%20cell%20cycle ; - :regulation%20of%20cell%20cycle ; - :regulation%20of%20cell%20cycle . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20cell%20cycle - rdf:type owl:NamedIndividual , - ; - :apoptotic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - ; - :spermatocyte ; - :spermatocyte ; - :spermatocyte ; - :spermatocyte . - -### http://www.co-ode.org/ontologies/ont.owl#spermatocyte - rdf:type owl:NamedIndividual , - ; - :Testicular%20atrophy ; - :Testicular%20atrophy . - -### http://www.co-ode.org/ontologies/ont.owl#Testis - rdf:type owl:NamedIndividual , - ; - :Testicular%20atrophy ; - :Testicular%20atrophy . - -### http://www.co-ode.org/ontologies/ont.owl#Testicular%20atrophy - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + a , . + + a , . + + ; + ; + a , . + + "review"^^ ; + a ; + "Histone deacetylase inhibition leading to testicular atrophy"^^ . diff --git a/models/AOP_213.ttl b/models/AOP_213.ttl index 7a6244c8..ca99941d 100644 --- a/models/AOP_213.ttl +++ b/models/AOP_213.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, Clonal Expansion of Altered Hepatic Foci"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Inhibition of fatty acid beta oxidation leading to nonalcoholic steatohepatitis (NASH)"^^ . diff --git a/models/AOP_214.ttl b/models/AOP_214.ttl index cc602bfe..fd3264d7 100644 --- a/models/AOP_214.ttl +++ b/models/AOP_214.ttl @@ -1,51 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, hepatocellular adenomas and carcinomas"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000011406 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004883 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor - rdf:type owl:NamedIndividual , - ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor%20activity - rdf:type owl:NamedIndividual , - . + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Network of SSRIs (selective serotonin reuptake inhibitors)"^^ . diff --git a/models/AOP_215.ttl b/models/AOP_215.ttl index 3334612e..f1c3cf42 100644 --- a/models/AOP_215.ttl +++ b/models/AOP_215.ttl @@ -1,51 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Liver fibrosis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_29985 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035249 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#L-glutamate%281-%29 - rdf:type owl:NamedIndividual , - ; - :synaptic%20transmission%2C%20glutamatergic ; - :synaptic%20transmission%2C%20glutamatergic ; - :synaptic%20transmission%2C%20glutamatergic ; - :synaptic%20transmission%2C%20glutamatergic . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20transmission%2C%20glutamatergic - rdf:type owl:NamedIndividual , - . + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Molecular events lead to epilepsy"^^ . diff --git a/models/AOP_216.ttl b/models/AOP_216.ttl index e4ca2b1a..5cd1fc3e 100644 --- a/models/AOP_216.ttl +++ b/models/AOP_216.ttl @@ -1,52 +1,23 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Alkylation, Protein"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of energy leading to population decline via DNA strand breaks and follicular atresia"^^ . diff --git a/models/AOP_218.ttl b/models/AOP_218.ttl index f20ad26b..5fd1f9c3 100644 --- a/models/AOP_218.ttl +++ b/models/AOP_218.ttl @@ -1,32 +1,8 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, Stellate cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# + a . + "development"^^ ; + a ; + "Inhibition of CYP7B activity leads to decreased reproductive success via decreased locomotor activity"^^ . diff --git a/models/AOP_219.ttl b/models/AOP_219.ttl index 6098e7d2..1e8e790b 100644 --- a/models/AOP_219.ttl +++ b/models/AOP_219.ttl @@ -1,32 +1,8 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Accumulation, Collagen"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# + a . + "development"^^ ; + a ; + "Inhibition of CYP7B activity leads to decreased reproductive success via decreased sexual behavior"^^ . diff --git a/models/AOP_220.ttl b/models/AOP_220.ttl index f693a383..6976850a 100644 --- a/models/AOP_220.ttl +++ b/models/AOP_220.ttl @@ -1,83 +1,41 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Tissue resident cell activation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0034599 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000235 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0002281 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000008555 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0005039 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000017294 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#cellular%20response%20to%20oxidative%20stress - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#macrophage - rdf:type owl:NamedIndividual , - ; - :macrophage%20activation%20involved%20in%20immune%20response . + a , . -### http://www.co-ode.org/ontologies/ont.owl#macrophage%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha - rdf:type owl:NamedIndividual , - ; - :hypoxia ; - :hypoxia . + a , . -### http://www.co-ode.org/ontologies/ont.owl#hypoxia - rdf:type owl:NamedIndividual , - . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#von%20Hippel-Lindau%20disease%20tumor%20suppressor - rdf:type owl:NamedIndividual , - ; - :hypoxia ; - :hypoxia . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Cyp2E1 Activation Leading to Liver Cancer"^^ . diff --git a/models/AOP_23.ttl b/models/AOP_23.ttl index 8e68941c..3e596ba2 100644 --- a/models/AOP_23.ttl +++ b/models/AOP_23.ttl @@ -1,243 +1,136 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Not Increased, Circulating Ketone Bodies"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004882 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0061370 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006703 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009306 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006898 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048599 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_81569 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone ; - :Luteinizing%20hormone ; - :Follicle%20stimulating%20hormone ; - :Follicle%20stimulating%20hormone ; - :Follicle%20stimulating%20hormone ; - :Follicle%20stimulating%20hormone . - -### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#Follicle%20stimulating%20hormone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20secretion - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20growth - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20development - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , , ; + , ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + , , , , ; + , , , , ; + , , , , ; + , , , , ; + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Androgen receptor agonism leading to reproductive dysfunction (in repeat-spawning fish)"^^ . diff --git a/models/AOP_230.ttl b/models/AOP_230.ttl index 681f1785..d047893f 100644 --- a/models/AOP_230.ttl +++ b/models/AOP_230.ttl @@ -1,51 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, Keratinocytes"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_29985 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035249 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#L-glutamate%281-%29 - rdf:type owl:NamedIndividual , - ; - :synaptic%20transmission%2C%20glutamatergic ; - :synaptic%20transmission%2C%20glutamatergic ; - :synaptic%20transmission%2C%20glutamatergic ; - :synaptic%20transmission%2C%20glutamatergic . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20transmission%2C%20glutamatergic - rdf:type owl:NamedIndividual , - . + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "presynaptic neuron 1 activation to epilepsy"^^ . diff --git a/models/AOP_233.ttl b/models/AOP_233.ttl index f4ded20c..6e38703d 100644 --- a/models/AOP_233.ttl +++ b/models/AOP_233.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Hepatotoxicity, Hepatopathy, including a constellation of observable effects"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0060081 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#membrane%20hyperpolarization - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Mu Opioid Receptor Agonism leading to Analgesia via K Channel Opening"^^ . diff --git a/models/AOP_235.ttl b/models/AOP_235.ttl index 04ea88f0..62a14e35 100644 --- a/models/AOP_235.ttl +++ b/models/AOP_235.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Changes/Inhibition, Cellular Homeostasis and Apoptosis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0060081 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#membrane%20hyperpolarization - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Serotonin 1A Receptor Agonism leading to Anti-depressant Activity via K Channel Opening"^^ . diff --git a/models/AOP_238.ttl b/models/AOP_238.ttl index e99d4dc6..8f427244 100644 --- a/models/AOP_238.ttl +++ b/models/AOP_238.ttl @@ -1,52 +1,23 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Thyroperoxidase, Inhibition"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of energy leading to population decline via DNA strand breaks and oocyte apoptosis"^^ . diff --git a/models/AOP_241.ttl b/models/AOP_241.ttl index 8d0773d3..c90b4d96 100644 --- a/models/AOP_241.ttl +++ b/models/AOP_241.ttl @@ -1,63 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Thyroxine (T4) in neuronal tissue, Decreased "^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_3815 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0032964 - rdf:type owl:Class . + a . + ; + a , . + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#collagen - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#collagen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#collagen - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#collagen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#collagen - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#collagen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Latent Transforming Growth Factor beta1 activation leads to pulmonary fibrosis"^^ . diff --git a/models/AOP_242.ttl b/models/AOP_242.ttl index b7942c69..27626916 100644 --- a/models/AOP_242.ttl +++ b/models/AOP_242.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Cognitive Function, Decreased "^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0005372 - rdf:type owl:Class . + ; + a , . + a . + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion - rdf:type owl:NamedIndividual , - ; - :life%20span%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#life%20span%20trait - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of lysyl oxidase leading to enhanced chronic fish toxicity"^^ . diff --git a/models/AOP_245.ttl b/models/AOP_245.ttl index 73cbdef9..872289f2 100644 --- a/models/AOP_245.ttl +++ b/models/AOP_245.ttl @@ -1,66 +1,35 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Hippocampal Physiology, Altered"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . + a . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . + a , . -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Reduction in photophosphorylation leading to growth inhibition in aquatic plants"^^ . diff --git a/models/AOP_25.ttl b/models/AOP_25.ttl index 424bcd8c..b5a53669 100644 --- a/models/AOP_25.ttl +++ b/models/AOP_25.ttl @@ -1,201 +1,110 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increased, Catabolism of Muscle Protein"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000006100 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0070330 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009306 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006898 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048599 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006703 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#aromatase - rdf:type owl:NamedIndividual , - ; - :aromatase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aromatase%20activity - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20secretion - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20growth - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20development - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , , ; + , ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + , , , , ; + , , , , ; + , , , , ; + , , , , ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Aromatase inhibition leading to reproductive dysfunction"^^ . diff --git a/models/AOP_256.ttl b/models/AOP_256.ttl index c18ac475..dc8682e7 100644 --- a/models/AOP_256.ttl +++ b/models/AOP_256.ttl @@ -1,69 +1,40 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Insufficient repair or mis-repair of pro-mutagenic DNA adducts"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CL_1000507 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0002113 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/Q000633 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#kidney%20tubule%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :toxicity . + a . -### http://www.co-ode.org/ontologies/ont.owl#kidney - rdf:type owl:NamedIndividual , - ; - :toxicity . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#toxicity - rdf:type owl:NamedIndividual , - . + ; + a , . + ; + ; + ; + ; + a , . + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of mitochondrial DNA polymerase gamma leading to kidney toxicity"^^ . diff --git a/models/AOP_257.ttl b/models/AOP_257.ttl index def47b7f..f32e79bf 100644 --- a/models/AOP_257.ttl +++ b/models/AOP_257.ttl @@ -1,96 +1,53 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "N/A, Mitochondrial dysfunction 1"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005764 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_1000507 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002113 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/Q000633 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#lysosome - rdf:type owl:NamedIndividual , - ; - :organelle%20disassembly ; - :organelle%20disassembly ; - :organelle%20disassembly ; - :organelle%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#lysosome - rdf:type owl:NamedIndividual , - ; - :organelle%20disassembly ; - :organelle%20disassembly ; - :organelle%20disassembly ; - :organelle%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#organelle%20disassembly - rdf:type owl:NamedIndividual , - ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#kidney%20tubule%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :toxicity . - -### http://www.co-ode.org/ontologies/ont.owl#kidney - rdf:type owl:NamedIndividual , - ; - :toxicity . - -### http://www.co-ode.org/ontologies/ont.owl#toxicity - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + "development"^^ ; + a ; + "Receptor mediated endocytosis and lysosomal overload leading to kidney toxicity"^^ . diff --git a/models/AOP_258.ttl b/models/AOP_258.ttl index 288f4ed0..873e1a69 100644 --- a/models/AOP_258.ttl +++ b/models/AOP_258.ttl @@ -1,92 +1,54 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Impairment, Learning and memory"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0008213 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_1000507 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0002113 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/Q000633 - rdf:type owl:Class . + a . + ; + a , . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#protein%20alkylation - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :cell%20death . + a . -### http://www.co-ode.org/ontologies/ont.owl#kidney%20tubule%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :toxicity . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#kidney - rdf:type owl:NamedIndividual , - ; - :toxicity . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#toxicity - rdf:type owl:NamedIndividual , - . + a , . + a . + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Renal protein alkylation leading to kidney toxicity"^^ . diff --git a/models/AOP_26.ttl b/models/AOP_26.ttl index c722a0f5..fe1b5662 100644 --- a/models/AOP_26.ttl +++ b/models/AOP_26.ttl @@ -1,135 +1,90 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Binding of antagonist, PPAR alpha"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0090534 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0005388 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005746 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16480 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060291 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion-transporting%20ATPase%20complex - rdf:type owl:NamedIndividual , - ; - :calcium-transporting%20ATPase%20activity ; - :calcium-transporting%20ATPase%20activity ; - :calcium-transporting%20ATPase%20activity ; - :calcium-transporting%20ATPase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#calcium-transporting%20ATPase%20activity - rdf:type owl:NamedIndividual , - ; - :calcium%20ion ; - :calcium%20ion ; - :calcium%20ion ; - :calcium%20ion . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :mitochondrial%20respiratory%20chain ; - :mitochondrial%20respiratory%20chain . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrial%20respiratory%20chain - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress . - -### http://www.co-ode.org/ontologies/ont.owl#long-term%20synaptic%20potentiation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide - rdf:type owl:NamedIndividual , - ; - :long-term%20synaptic%20potentiation ; - :long-term%20synaptic%20potentiation ; - :long-term%20synaptic%20potentiation ; - :long-term%20synaptic%20potentiation . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + ; + a , . + + ; + a , . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Calcium-mediated neuronal ROS production and energy imbalance"^^ . diff --git a/models/AOP_263.ttl b/models/AOP_263.ttl index 2d964c3b..e50c6497 100644 --- a/models/AOP_263.ttl +++ b/models/AOP_263.ttl @@ -1,135 +1,71 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased, Neuronal network function in adult brain"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1901691 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0017077 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051881 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005623 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#proton%20binding - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20phosphorylation%20uncoupler%20activity - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20mitochondrial%20membrane%20potential - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :growth . - -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . - -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + , , ; + , , ; + , , ; + , , ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation"^^ . diff --git a/models/AOP_264.ttl b/models/AOP_264.ttl index 8768fbf6..43c29a55 100644 --- a/models/AOP_264.ttl +++ b/models/AOP_264.ttl @@ -1,118 +1,60 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Binding of agonist, Ionotropic glutamate receptors"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1901691 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0017077 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051881 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#proton%20binding - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20phosphorylation%20uncoupler%20activity - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20mitochondrial%20membrane%20potential - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . - -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . - + a . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + , , ; + , , ; + , , ; + , , ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + a , . + + "development"^^ ; + a ; + "Uncoupling of oxidative phosphorylation leading to growth inhibition via ATP depletion associated cell death"^^ . diff --git a/models/AOP_265.ttl b/models/AOP_265.ttl index 32d8444e..b56bb32a 100644 --- a/models/AOP_265.ttl +++ b/models/AOP_265.ttl @@ -1,118 +1,60 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Neuroinflammation"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1901691 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0017077 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051881 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#proton%20binding - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20phosphorylation%20uncoupler%20activity - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20mitochondrial%20membrane%20potential - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . - -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . - + a . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + , , ; + , , ; + , , ; + , , ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + a , . + + "development"^^ ; + a ; + "Uncoupling of oxidative phosphorylation leading to growth inhibition via increased cytosolic calcium"^^ . diff --git a/models/AOP_266.ttl b/models/AOP_266.ttl index 30ee92dd..b9f67a9e 100644 --- a/models/AOP_266.ttl +++ b/models/AOP_266.ttl @@ -1,114 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "impaired, Fertility"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1901691 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0017077 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051881 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#proton%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20phosphorylation%20uncoupler%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20mitochondrial%20membrane%20potential - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . - -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a , . + + a . + + , , ; + , , ; + , , ; + , , ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased Na-K ATPase activity"^^ . diff --git a/models/AOP_267.ttl b/models/AOP_267.ttl index 8d786071..d758aae8 100644 --- a/models/AOP_267.ttl +++ b/models/AOP_267.ttl @@ -1,114 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, Luteinizing hormone (LH) "^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1901691 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0017077 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051881 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#proton%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20phosphorylation%20uncoupler%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20mitochondrial%20membrane%20potential - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . - -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a , . + + a . + + , , ; + , , ; + , , ; + , , ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "Uncoupling of oxidative phosphorylation leading to growth inhibition via glucose depletion"^^ . diff --git a/models/AOP_268.ttl b/models/AOP_268.ttl index 728ecf89..f0c33403 100644 --- a/models/AOP_268.ttl +++ b/models/AOP_268.ttl @@ -1,114 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Hyperplasia, Leydig cell"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1901691 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0017077 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051881 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding ; - :proton%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#proton%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity ; - :oxidative%20phosphorylation%20uncoupler%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20phosphorylation%20uncoupler%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential ; - :regulation%20of%20mitochondrial%20membrane%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20mitochondrial%20membrane%20potential - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . - -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a , . + + a . + + , , ; + , , ; + , , ; + , , ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "Uncoupling of oxidative phosphorylation leading to growth inhibition via mitochondrial swelling"^^ . diff --git a/models/AOP_27.ttl b/models/AOP_27.ttl index 622609d3..6c9c327f 100644 --- a/models/AOP_27.ttl +++ b/models/AOP_27.ttl @@ -1,150 +1,93 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "stabilization, PPAR alpha co-repressor"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003549 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006810 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000011396 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0001970 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/FMA_84050 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0050663 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006954 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D002779 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#bile - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#bile%20acid%20receptor - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :cholestasis ; - :cholestasis ; - :cholestasis ; - :cholestasis . - -### http://www.co-ode.org/ontologies/ont.owl#cholestasis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :cholestasis ; - :cholestasis ; - :cholestasis ; - :cholestasis . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :cholestasis . - -### http://www.co-ode.org/ontologies/ont.owl#bile - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#Cytokine - rdf:type owl:NamedIndividual , - ; - :cytokine%20secretion ; - :cytokine%20secretion ; - :cytokine%20secretion ; - :cytokine%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#cytokine%20secretion - rdf:type owl:NamedIndividual , - ; - :inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#cholestasis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress . - -### http://www.co-ode.org/ontologies/ont.owl#cholestasis - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + "review"^^ ; + a ; + "Cholestatic Liver Injury induced by Inhibition of the Bile Salt Export Pump (ABCB11)"^^ . diff --git a/models/AOP_271.ttl b/models/AOP_271.ttl index 6bba1916..1c59e0e7 100644 --- a/models/AOP_271.ttl +++ b/models/AOP_271.ttl @@ -1,120 +1,84 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, testosterone level"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000016584 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004447 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009306 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000006100 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0070330 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase - rdf:type owl:NamedIndividual , - ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :egg%20quantity ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a , . + + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Inhibition of thyroid peroxidase leading to impaired fertility in fish"^^ . diff --git a/models/AOP_272.ttl b/models/AOP_272.ttl index d87146ee..454c2890 100644 --- a/models/AOP_272.ttl +++ b/models/AOP_272.ttl @@ -1,76 +1,38 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Testosterone synthesis in Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . + a . -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . + a , . -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of energy leading to lung cancer"^^ . diff --git a/models/AOP_273.ttl b/models/AOP_273.ttl index 2935d5b7..d029eb87 100644 --- a/models/AOP_273.ttl +++ b/models/AOP_273.ttl @@ -1,91 +1,49 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Cholesterol transport in mitochondria"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000031316 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006120 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008137 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_36080 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D057165 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + ; + a , . + a . + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#NADH-ubiquinone%20oxidoreductase%20chain%201 - rdf:type owl:NamedIndividual , - ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#NADH%20dehydrogenase%20%28ubiquinone%29%20activity - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :Proteostasis%20deficiencies . + a . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :Proteostasis%20deficiencies . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#protein - rdf:type owl:NamedIndividual , - ; - :Proteostasis%20deficiencies . + a , . -### http://www.co-ode.org/ontologies/ont.owl#Proteostasis%20deficiencies - rdf:type owl:NamedIndividual , - ; - :cell%20death . + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Mitochondrial complex inhibition leading to liver injury"^^ . diff --git a/models/AOP_274.ttl b/models/AOP_274.ttl index b737ff1a..1f3461a4 100644 --- a/models/AOP_274.ttl +++ b/models/AOP_274.ttl @@ -1,51 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Agonism, Estrogen receptor"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000008478 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004857 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#histone%20deacetylase%201 - rdf:type owl:NamedIndividual , - ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity . + a , . -### http://www.co-ode.org/ontologies/ont.owl#enzyme%20inhibitor%20activity - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Histone deacetylase inhibition leads to impeded craniofacial development"^^ . diff --git a/models/AOP_275.ttl b/models/AOP_275.ttl index f6006296..c415f808 100644 --- a/models/AOP_275.ttl +++ b/models/AOP_275.ttl @@ -1,79 +1,46 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "skewed, sex ratio"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000008478 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004857 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_15358 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0031399 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#histone%20deacetylase%201 - rdf:type owl:NamedIndividual , - ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity ; - :enzyme%20inhibitor%20activity . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#enzyme%20inhibitor%20activity - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20protein%20modification%20process . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#histone - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20protein%20modification%20process ; - :regulation%20of%20protein%20modification%20process ; - :regulation%20of%20protein%20modification%20process ; - :regulation%20of%20protein%20modification%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20protein%20modification%20process - rdf:type owl:NamedIndividual , - ; - :gene%20expression . + a . -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . + ; + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Histone deacetylase inhibition leads to neural tube defects"^^ . diff --git a/models/AOP_276.ttl b/models/AOP_276.ttl index 273f9028..76869ce8 100644 --- a/models/AOP_276.ttl +++ b/models/AOP_276.ttl @@ -1,68 +1,33 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Agonism, Estrogen receptor"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000031316 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006120 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008137 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#NADH-ubiquinone%20oxidoreductase%20chain%201 - rdf:type owl:NamedIndividual , - ; - :mitochondrial%20electron%20transport%2C%20NADH%20to%20ubiquinone ; - :mitochondrial%20electron%20transport%2C%20NADH%20to%20ubiquinone ; - :mitochondrial%20electron%20transport%2C%20NADH%20to%20ubiquinone ; - :mitochondrial%20electron%20transport%2C%20NADH%20to%20ubiquinone . + a . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrial%20electron%20transport%2C%20NADH%20to%20ubiquinone - rdf:type owl:NamedIndividual , - ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity . + , ; + , ; + , ; + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#NADH-ubiquinone%20oxidoreductase%20chain%201 - rdf:type owl:NamedIndividual , - ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity . + a , . -### http://www.co-ode.org/ontologies/ont.owl#NADH%20dehydrogenase%20%28ubiquinone%29%20activity - rdf:type owl:NamedIndividual , - . + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of complex I of the electron transport chain leading to chemical induced Fanconi syndrome"^^ . diff --git a/models/AOP_277.ttl b/models/AOP_277.ttl index cf8d2b9a..410fc4d4 100644 --- a/models/AOP_277.ttl +++ b/models/AOP_277.ttl @@ -1,51 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Vitellogenin synthesis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000001753 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007249 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#transcription%20factor%20NF-kappa-B%20subunit - rdf:type owl:NamedIndividual , - ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling . + a , . -### http://www.co-ode.org/ontologies/ont.owl#I-kappaB%20kinase/NF-kappaB%20signaling - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response"^^ . diff --git a/models/AOP_278.ttl b/models/AOP_278.ttl index fd530103..d83f191f 100644 --- a/models/AOP_278.ttl +++ b/models/AOP_278.ttl @@ -1,58 +1,30 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increase, Plasma vitellogenin concentrations"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000001753 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007249 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#transcription%20factor%20NF-kappa-B%20subunit - rdf:type owl:NamedIndividual , - ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :I-kappaB%20kinase%2FNF-kappaB%20signaling . + a . -### http://www.co-ode.org/ontologies/ont.owl#I-kappaB%20kinase/NF-kappaB%20signaling - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "IKK complex inhibition leading to liver injury"^^ . diff --git a/models/AOP_28.ttl b/models/AOP_28.ttl index 7eb29f17..2448cd2e 100644 --- a/models/AOP_28.ttl +++ b/models/AOP_28.ttl @@ -1,163 +1,100 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Fatty Acid Beta Oxidation, Decreased"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000013427 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004666 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013428 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15551 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006816 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17544 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015701 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0005079 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0044703 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%201 - rdf:type owl:NamedIndividual , - ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin-endoperoxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%202 - rdf:type owl:NamedIndividual , - ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity ; - :prostaglandin-endoperoxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin-endoperoxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 ; - :prostaglandin%20E2 . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20E2 - rdf:type owl:NamedIndividual , - ; - :eggshell ; - :eggshell . - -### http://www.co-ode.org/ontologies/ont.owl#eggshell - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :bicarbonate%20transport ; - :bicarbonate%20transport ; - :bicarbonate%20transport ; - :bicarbonate%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport - rdf:type owl:NamedIndividual , - ; - :eggshell ; - :eggshell ; - :eggshell ; - :eggshell . - -### http://www.co-ode.org/ontologies/ont.owl#hydrogencarbonate - rdf:type owl:NamedIndividual , - ; - :bicarbonate%20transport ; - :bicarbonate%20transport ; - :bicarbonate%20transport ; - :bicarbonate%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#bicarbonate%20transport - rdf:type owl:NamedIndividual , - ; - :eggshell ; - :eggshell ; - :eggshell ; - :eggshell . - -### http://www.co-ode.org/ontologies/ont.owl#eggshell - rdf:type owl:NamedIndividual , - ; - :multi-organism%20reproductive%20process ; - :multi-organism%20reproductive%20process ; - :multi-organism%20reproductive%20process ; - :multi-organism%20reproductive%20process . - -### http://www.co-ode.org/ontologies/ont.owl#multi-organism%20reproductive%20process - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + , , ; + , , ; + , , ; + , , ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Cyclooxygenase inhibition leading reproductive failure"^^ . diff --git a/models/AOP_280.ttl b/models/AOP_280.ttl index c5097296..fe6d4c82 100644 --- a/models/AOP_280.ttl +++ b/models/AOP_280.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, glomerular rupture and renal hemorrhaging"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0006954 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#inflammatory%20response - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Ī±-diketone-induced bronchiolitis obliterans"^^ . diff --git a/models/AOP_281.ttl b/models/AOP_281.ttl index 4edc04b5..78a78960 100644 --- a/models/AOP_281.ttl +++ b/models/AOP_281.ttl @@ -1,181 +1,125 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, nephropathy"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003626 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0003990 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_15355 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000001488 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0031789 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0017146 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004972 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006816 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000540 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/HP_0011185 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002229 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000955 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000703 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_29985 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0035249 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholinesterase - rdf:type owl:NamedIndividual , - ; - :acetylcholinesterase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholinesterase%20activity - rdf:type owl:NamedIndividual , - ; - :acetylcholine ; - :acetylcholine ; - :acetylcholine ; - :acetylcholine . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine - rdf:type owl:NamedIndividual , - ; - :G-protein%20coupled%20acetylcholine%20receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#muscarinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :G-protein%20coupled%20acetylcholine%20receptor%20binding ; - :G-protein%20coupled%20acetylcholine%20receptor%20binding ; - :G-protein%20coupled%20acetylcholine%20receptor%20binding ; - :G-protein%20coupled%20acetylcholine%20receptor%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#G-protein%20coupled%20acetylcholine%20receptor%20binding - rdf:type owl:NamedIndividual , - ; - :EEG%20with%20focal%20epileptiform%20discharges . - -### http://www.co-ode.org/ontologies/ont.owl#neuron - rdf:type owl:NamedIndividual , - ; - :EEG%20with%20focal%20epileptiform%20discharges ; - :EEG%20with%20focal%20epileptiform%20discharges . - -### http://www.co-ode.org/ontologies/ont.owl#EEG%20with%20focal%20epileptiform%20discharges - rdf:type owl:NamedIndividual , - ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport - rdf:type owl:NamedIndividual , - ; - :secondary%20generalized%20seizure . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :neurodegeneration . - -### http://www.co-ode.org/ontologies/ont.owl#neurodegeneration - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#brain - rdf:type owl:NamedIndividual , - ; - :secondary%20generalized%20seizure . - -### http://www.co-ode.org/ontologies/ont.owl#secondary%20generalized%20seizure - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + "review"^^ ; + a ; + "Acetylcholinesterase Inhibition Leading to Neurodegeneration"^^ . diff --git a/models/AOP_284.ttl b/models/AOP_284.ttl index 20d97e85..7e9fe750 100644 --- a/models/AOP_284.ttl +++ b/models/AOP_284.ttl @@ -1,48 +1,24 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduced levels of BDNF"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16856 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0016209 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005746 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001909 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins involved in protection against oxidative stress leads to chronic kidney disease"^^ . diff --git a/models/AOP_285.ttl b/models/AOP_285.ttl index 2fd438cd..a9512deb 100644 --- a/models/AOP_285.ttl +++ b/models/AOP_285.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decrease of synaptogenesis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Inhibition of N-linked glycosylation leads to liver injury"^^ . diff --git a/models/AOP_286.ttl b/models/AOP_286.ttl index da7c8b05..ae1264fc 100644 --- a/models/AOP_286.ttl +++ b/models/AOP_286.ttl @@ -1,84 +1,48 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Impairment, Learning and memory"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005623 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . + ; + a , . + a . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :growth . + a , . -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . + a . + ; + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Mitochondrial complex III antagonism leading to growth inhibition (1)"^^ . diff --git a/models/AOP_287.ttl b/models/AOP_287.ttl index 738b483b..2d68ad09 100644 --- a/models/AOP_287.ttl +++ b/models/AOP_287.ttl @@ -1,45 +1,22 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - " Thyroxine (T4) in serum, Decreased"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Mitochondrial complex III antagonism leading to growth inhibition (2)"^^ . diff --git a/models/AOP_289.ttl b/models/AOP_289.ttl index c8b7822f..086d70f2 100644 --- a/models/AOP_289.ttl +++ b/models/AOP_289.ttl @@ -1,77 +1,45 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, Na+/I- symporter (NIS)"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins . + a . -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :egg%20quantity ; - :egg%20quantity . + a . -### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + ; + ; + a , . + ; + a , . + ; + ; + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of 5Ī±-reductase leading to impaired fecundity in female fish"^^ . diff --git a/models/AOP_29.ttl b/models/AOP_29.ttl index 73710eaa..6f45b84f 100644 --- a/models/AOP_29.ttl +++ b/models/AOP_29.ttl @@ -1,133 +1,85 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, Plasma 17beta-estradiol concentrations"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0030284 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D007674 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019098 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002164 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0003133 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032502 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor - rdf:type owl:NamedIndividual , - ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :reproductive%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20organ - rdf:type owl:NamedIndividual , - ; - :developmental%20process ; - :developmental%20process ; - :developmental%20process ; - :developmental%20process . - -### http://www.co-ode.org/ontologies/ont.owl#developmental%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#larval%20development - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#Kidney%20Diseases - rdf:type owl:NamedIndividual , - ; - :larval%20development . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20behavior - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :Kidney%20Diseases . + a . + a . + a . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + ; + a , . + + a . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a , . + + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Estrogen receptor agonism leading to reproductive dysfunction"^^ . diff --git a/models/AOP_290.ttl b/models/AOP_290.ttl index 89e66e63..43100a7f 100644 --- a/models/AOP_290.ttl +++ b/models/AOP_290.ttl @@ -1,84 +1,48 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decrease of neuronal network function"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005623 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . + ; + a , . + a . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :growth . + a , . -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . + a . + ; + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Mitochondrial ATP synthase antagonism leading to growth inhibition (1)"^^ . diff --git a/models/AOP_291.ttl b/models/AOP_291.ttl index 18535c1f..89e1b6e9 100644 --- a/models/AOP_291.ttl +++ b/models/AOP_291.ttl @@ -1,66 +1,35 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Thyroid hormone synthesis, Decreased"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0000468 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0040007 - rdf:type owl:Class . + a . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism - rdf:type owl:NamedIndividual , - ; - :growth ; - :growth ; - :growth ; - :growth . + a , . -### http://www.co-ode.org/ontologies/ont.owl#growth - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Mitochondrial ATP synthase antagonism leading to growth inhibition (2)"^^ . diff --git a/models/AOP_292.ttl b/models/AOP_292.ttl index 2230bd03..894ac1dd 100644 --- a/models/AOP_292.ttl +++ b/models/AOP_292.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, AhR"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of tyrosinase leads to decreased population in fish"^^ . diff --git a/models/AOP_293.ttl b/models/AOP_293.ttl index 1ac387c9..60f717e7 100644 --- a/models/AOP_293.ttl +++ b/models/AOP_293.ttl @@ -1,152 +1,75 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Suppression, VLDL secretion"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D001943 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002263 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002526 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000738 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Breast%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#Breast%20Neoplasms - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - ; - :acute%20inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response . - -### http://www.co-ode.org/ontologies/ont.owl#acute%20inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :Breast%20Neoplasms ; - :Breast%20Neoplasms ; - :Breast%20Neoplasms ; - :Breast%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#leukocyte - rdf:type owl:NamedIndividual , - ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - ; - :acute%20inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Breast%20Neoplasms - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "Increased DNA damage leading to increased risk of breast cancer"^^ . diff --git a/models/AOP_294.ttl b/models/AOP_294.ttl index 33c41b54..24607cf9 100644 --- a/models/AOP_294.ttl +++ b/models/AOP_294.ttl @@ -1,144 +1,75 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Inhibition, Mitochondrial fatty acid beta-oxidation"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D001943 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002263 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002526 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000738 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :Breast%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#Breast%20Neoplasms - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - ; - :acute%20inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - ; - :acute%20inflammatory%20response . - -### http://www.co-ode.org/ontologies/ont.owl#acute%20inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :Breast%20Neoplasms ; - :Breast%20Neoplasms ; - :Breast%20Neoplasms ; - :Breast%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#leukocyte - rdf:type owl:NamedIndividual , - ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response ; - :cell%20activation%20involved%20in%20immune%20response . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Breast%20Neoplasms - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "Increased reactive oxygen and nitrogen species (RONS) leading to increased risk of breast cancer"^^ . diff --git a/models/AOP_296.ttl b/models/AOP_296.ttl index 4f91f433..8ccec48b 100644 --- a/models/AOP_296.ttl +++ b/models/AOP_296.ttl @@ -1,95 +1,46 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased, PCK1 expression (control point for glycolysis/gluconeogenesis pathway)"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1901031 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20response%20to%20reactive%20oxygen%20species ; - :regulation%20of%20response%20to%20reactive%20oxygen%20species ; - :regulation%20of%20response%20to%20reactive%20oxygen%20species ; - :regulation%20of%20response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20response%20to%20reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + ; + a , . + + a , . + + a . + + a , . + + a . + + ; + a , . + + "development"^^ ; + a ; + "Oxidative DNA damage leading to chromosomal aberrations and mutations"^^ . diff --git a/models/AOP_297.ttl b/models/AOP_297.ttl index 0aa97779..379cce58 100644 --- a/models/AOP_297.ttl +++ b/models/AOP_297.ttl @@ -1,66 +1,35 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Accumulation, Triglyceride"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/UBERON_0000970 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0002090 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#eye - rdf:type owl:NamedIndividual , - ; - :vision%20trait ; - :vision%20trait . + a . -### http://www.co-ode.org/ontologies/ont.owl#vision%20trait - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of retinaldehyde dehydrogenase leads to population decline"^^ . diff --git a/models/AOP_298.ttl b/models/AOP_298.ttl index c8898ea3..5de36e1f 100644 --- a/models/AOP_298.ttl +++ b/models/AOP_298.ttl @@ -1,133 +1,74 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Accumulation, Liver lipid"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005575 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001837 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_2001038 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000302 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000030936 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0061355 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1990907 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1904863 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#response%20to%20reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :Wnt%20protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#protein-serine%20O-palmitoleoyltransferase%20porcupine - rdf:type owl:NamedIndividual , - ; - :Wnt%20protein%20secretion ; - :Wnt%20protein%20secretion ; - :Wnt%20protein%20secretion ; - :Wnt%20protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#Wnt%20protein%20secretion - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20beta-catenin-TCF%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#protein-serine%20O-palmitoleoyltransferase%20porcupine - rdf:type owl:NamedIndividual , - ; - :Wnt%20protein%20secretion ; - :Wnt%20protein%20secretion ; - :Wnt%20protein%20secretion ; - :Wnt%20protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#Wnt%20protein%20secretion - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20beta-catenin-TCF%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#beta-catenin-TCF%20complex - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20beta-catenin-TCF%20complex%20assembly ; - :regulation%20of%20beta-catenin-TCF%20complex%20assembly ; - :regulation%20of%20beta-catenin-TCF%20complex%20assembly ; - :regulation%20of%20beta-catenin-TCF%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20beta-catenin-TCF%20complex%20assembly - rdf:type owl:NamedIndividual , - ; - :epithelial%20to%20mesenchymal%20transition . - -### http://www.co-ode.org/ontologies/ont.owl#cellular_component - rdf:type owl:NamedIndividual , - ; - :epithelial%20to%20mesenchymal%20transition ; - :epithelial%20to%20mesenchymal%20transition ; - :epithelial%20to%20mesenchymal%20transition ; - :epithelial%20to%20mesenchymal%20transition . - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20to%20mesenchymal%20transition - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20cellular%20response%20to%20drug . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20cellular%20response%20to%20drug - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a , . + + ; + a , . + + "review"^^ ; + a ; + "Increases in cellular reactive oxygen species and chronic reactive oxygen species leading to human treatment-resistant gastric cancer"^^ . diff --git a/models/AOP_299.ttl b/models/AOP_299.ttl index ccc1b7e3..636b3f1e 100644 --- a/models/AOP_299.ttl +++ b/models/AOP_299.ttl @@ -1,67 +1,32 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Up Regulation, CD36"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of energy leading to population decline via DNA oxidation and follicular atresia"^^ . diff --git a/models/AOP_3.ttl b/models/AOP_3.ttl index 8b865bdb..281522c9 100644 --- a/models/AOP_3.ttl +++ b/models/AOP_3.ttl @@ -1,149 +1,92 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "N/A, Unknown"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000031316 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008137 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006120 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_36080 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D057165 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000129 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001847 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000127 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003244 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D020734 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :Proteostasis%20deficiencies . - -### http://www.co-ode.org/ontologies/ont.owl#protein - rdf:type owl:NamedIndividual , - ; - :Proteostasis%20deficiencies . - -### http://www.co-ode.org/ontologies/ont.owl#Proteostasis%20deficiencies - rdf:type owl:NamedIndividual , - ; - :loss%20of%20dopaminergic%20neurons . - -### http://www.co-ode.org/ontologies/ont.owl#loss%20of%20dopaminergic%20neurons - rdf:type owl:NamedIndividual , - ; - :Parkinsonian%20disorders . - -### http://www.co-ode.org/ontologies/ont.owl#loss%20of%20dopaminergic%20neurons - rdf:type owl:NamedIndividual , - ; - :Parkinsonian%20disorders . - -### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :loss%20of%20dopaminergic%20neurons ; - :loss%20of%20dopaminergic%20neurons . - -### http://www.co-ode.org/ontologies/ont.owl#astrocyte - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :loss%20of%20dopaminergic%20neurons ; - :loss%20of%20dopaminergic%20neurons . - -### http://www.co-ode.org/ontologies/ont.owl#Parkinsonian%20disorders - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#NADH-ubiquinone%20oxidoreductase%20chain%201 - rdf:type owl:NamedIndividual , - ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; - :NADH%20dehydrogenase%20%28ubiquinone%29%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#NADH%20dehydrogenase%20%28ubiquinone%29%20activity - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :Proteostasis%20deficiencies . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + a . + + ; + a , . + + a , . + + "review"^^ ; + a ; + "Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits"^^ . diff --git a/models/AOP_30.ttl b/models/AOP_30.ttl index d9e195f8..ceee9dfd 100644 --- a/models/AOP_30.ttl +++ b/models/AOP_30.ttl @@ -1,174 +1,97 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Reduction, 17beta-estradiol synthesis by ovarian granulosa cells"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030284 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009306 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006898 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048599 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor - rdf:type owl:NamedIndividual , - ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity ; - :estrogen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20secretion - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20growth - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20development - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + , , , , ; + , , , , ; + , , , , ; + , , , , ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + , ; + a , . + + "review"^^ ; + a ; + "Estrogen receptor antagonism leading to reproductive dysfunction"^^ . diff --git a/models/AOP_300.ttl b/models/AOP_300.ttl index 2a27deae..e8eba8e1 100644 --- a/models/AOP_300.ttl +++ b/models/AOP_300.ttl @@ -1,103 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increased, FA Influx"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/UBERON_0002421 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007420 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0045202 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007268 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050890 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - ; - :brain%20development . - -### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation - rdf:type owl:NamedIndividual , - ; - :brain%20development ; - :brain%20development ; - :brain%20development ; - :brain%20development . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20development - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#synapse - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission - rdf:type owl:NamedIndividual , - ; - :learning%20or%20memory ; - :cognition . - -### http://www.co-ode.org/ontologies/ont.owl#learning%20or%20memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cognition - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + , ; + a , . + + a , . + + , ; + , ; + , ; + , ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "Thyroid Receptor Antagonism and Subsequent Adverse Neurodevelopmental Outcomes in Mammals"^^ . diff --git a/models/AOP_302.ttl b/models/AOP_302.ttl index 2a1dd3d7..d7e04f9e 100644 --- a/models/AOP_302.ttl +++ b/models/AOP_302.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, LDL uptake"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/VT_0002327 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20function%20trait - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Lung surfactant function inhibition leading to decreased lung function"^^ . diff --git a/models/AOP_303.ttl b/models/AOP_303.ttl index aad3377f..f8c44086 100644 --- a/models/AOP_303.ttl +++ b/models/AOP_303.ttl @@ -1,85 +1,49 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Up Regulation, CYP1A1"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CL_0000235 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006909 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/FMA_84050 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0050663 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#macrophage - rdf:type owl:NamedIndividual , - ; - :phagocytosis ; - :phagocytosis ; - :phagocytosis ; - :phagocytosis . + a . -### http://www.co-ode.org/ontologies/ont.owl#phagocytosis - rdf:type owl:NamedIndividual , - ; - :cytokine%20secretion . + a , . -### http://www.co-ode.org/ontologies/ont.owl#Cytokine - rdf:type owl:NamedIndividual , - ; - :cytokine%20secretion ; - :cytokine%20secretion ; - :cytokine%20secretion ; - :cytokine%20secretion . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cytokine%20secretion - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - . + ; + a , . + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Frustrated phagocytosis-induced lung cancer"^^ . diff --git a/models/AOP_305.ttl b/models/AOP_305.ttl index d769e3a8..4cf51c7a 100644 --- a/models/AOP_305.ttl +++ b/models/AOP_305.ttl @@ -1,45 +1,22 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Suppression, Constitutive androstane receptor, NR1l3"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/FMA_264621 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030521 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "5Ī±-reductase inhibition leading to short anogenital distance (AGD) in male (mammalian) offspring"^^ . diff --git a/models/AOP_306.ttl b/models/AOP_306.ttl index 2e3dec1c..ea11f1c0 100644 --- a/models/AOP_306.ttl +++ b/models/AOP_306.ttl @@ -1,51 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, SREBF1"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/FMA_264621 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030521 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#Musculature%20of%20male%20perineum - rdf:type owl:NamedIndividual , - ; - :androgen%20receptor%20signaling%20pathway ; - :androgen%20receptor%20signaling%20pathway ; - :androgen%20receptor%20signaling%20pathway ; - :androgen%20receptor%20signaling%20pathway . + a , . -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Androgen receptor (AR) antagonism leading to short anogenital distance (AGD) in male (mammalian) offspring"^^ . diff --git a/models/AOP_307.ttl b/models/AOP_307.ttl index 6d8fd689..b342f22a 100644 --- a/models/AOP_307.ttl +++ b/models/AOP_307.ttl @@ -1,86 +1,50 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, ChREBP"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0061370 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/FMA_264621 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030521 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#testosterone%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression . + a . -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - ; - :androgen%20receptor%20signaling%20pathway . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#Musculature%20of%20male%20perineum - rdf:type owl:NamedIndividual , - ; - :androgen%20receptor%20signaling%20pathway ; - :androgen%20receptor%20signaling%20pathway ; - :androgen%20receptor%20signaling%20pathway ; - :androgen%20receptor%20signaling%20pathway . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - . + ; + a , . + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Decreased testosterone synthesis leading to short anogenital distance (AGD) in male (mammalian) offspring"^^ . diff --git a/models/AOP_309.ttl b/models/AOP_309.ttl index 4770baa4..ad275453 100644 --- a/models/AOP_309.ttl +++ b/models/AOP_309.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Liver Steatosis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Luteinizing hormone receptor antagonism leading to reproductive dysfunction"^^ . diff --git a/models/AOP_31.ttl b/models/AOP_31.ttl index f1962b7e..73f85a8b 100644 --- a/models/AOP_31.ttl +++ b/models/AOP_31.ttl @@ -1,215 +1,98 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "impaired, Fertility"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0006788 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_P69905 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006461 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_35703 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0042541 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030492 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007749 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000232 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0010019 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006486 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D008708 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_35143 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D003490 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#heme%20oxidation - rdf:type owl:NamedIndividual , - ; - :hemoglobin%20biosynthetic%20process ; - :hemoglobin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :hemolysis . - -### http://www.co-ode.org/ontologies/ont.owl#hemolysis - rdf:type owl:NamedIndividual , - ; - :hemosiderosis ; - :hemosiderosis . - -### http://www.co-ode.org/ontologies/ont.owl#xenobiotic - rdf:type owl:NamedIndividual , - ; - :hemoglobin%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#hemoglobin%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#hemoglobin%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#erythrocyte - rdf:type owl:NamedIndividual , - ; - :Methemoglobinemia ; - :Methemoglobinemia ; - :hemoglobin ; - :hemoglobin ; - :erythrocyte ; - :erythrocyte . - -### http://www.co-ode.org/ontologies/ont.owl#liver%20vascular%20congestion - rdf:type owl:NamedIndividual , - ; - :Methemoglobinemia ; - :hemoglobin ; - :erythrocyte . - -### http://www.co-ode.org/ontologies/ont.owl#Methemoglobinemia - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - -### http://www.co-ode.org/ontologies/ont.owl#hemoglobin - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - -### http://www.co-ode.org/ontologies/ont.owl#erythrocyte - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - -### http://www.co-ode.org/ontologies/ont.owl#hemosiderosis - rdf:type owl:NamedIndividual , - ; - :Methemoglobinemia ; - :Methemoglobinemia ; - :hemoglobin ; - :hemoglobin ; - :erythrocyte ; - :erythrocyte . - -### http://www.co-ode.org/ontologies/ont.owl#glucose-6-phosphate%201-dehydrogenase - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Cyanosis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Methemoglobinemia - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - -### http://www.co-ode.org/ontologies/ont.owl#hemoglobin - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - -### http://www.co-ode.org/ontologies/ont.owl#erythrocyte - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - -### http://www.co-ode.org/ontologies/ont.owl#hemolysis - rdf:type owl:NamedIndividual , - ; - :hemosiderosis ; - :hemosiderosis . - -### http://www.co-ode.org/ontologies/ont.owl#Methemoglobinemia - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - -### http://www.co-ode.org/ontologies/ont.owl#hemoglobin - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - -### http://www.co-ode.org/ontologies/ont.owl#erythrocyte - rdf:type owl:NamedIndividual , - ; - :Cyanosis ; - :Cyanosis . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + , , , ; + , , , ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + ; + ; + a , . + + a , . + + a , . + + ; + ; + a , . + + , , ; + , , ; + a , . + + , , ; + a , . + + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Oxidation of iron in hemoglobin leading to hematotoxicity"^^ . diff --git a/models/AOP_310.ttl b/models/AOP_310.ttl index 68d5f639..7c3f342f 100644 --- a/models/AOP_310.ttl +++ b/models/AOP_310.ttl @@ -1,235 +1,125 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Triglyceride formation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006703 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009306 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006898 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001555 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048599 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046983 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004303 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity ; - :aryl%20hydrocarbon%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator - rdf:type owl:NamedIndividual , - ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity ; - :protein%20dimerization%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion ; - :protein%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20secretion - rdf:type owl:NamedIndividual , - ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins ; - :vitellogenins . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20growth ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development ; - :oocyte%20development . - -### http://www.co-ode.org/ontologies/ont.owl#vitellogenins - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20growth - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#oocyte%20development - rdf:type owl:NamedIndividual , - ; - :egg%20quantity . - -### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , , ; + , ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + , , , , ; + , , , , ; + , , , , ; + , , , , ; + a , . + + "development"^^ ; + a ; + "Embryonic Activation of the AHR leading to Reproductive failure, via epigenetic down-regulation of GnRHR"^^ . diff --git a/models/AOP_311.ttl b/models/AOP_311.ttl index 777186ca..6057d9e8 100644 --- a/models/AOP_311.ttl +++ b/models/AOP_311.ttl @@ -1,67 +1,32 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Up Regulation, CD36"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of energy leading to population decline via DNA oxidation and oocyte apoptosis"^^ . diff --git a/models/AOP_312.ttl b/models/AOP_312.ttl index 00e23d59..43b6a730 100644 --- a/models/AOP_312.ttl +++ b/models/AOP_312.ttl @@ -1,113 +1,67 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Up Regulation, SCD-1"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003626 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003990 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15355 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001393 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001399 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000753 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholinesterase - rdf:type owl:NamedIndividual , - ; - :acetylcholinesterase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholinesterase%20activity - rdf:type owl:NamedIndividual , - ; - :acetylcholine ; - :acetylcholine ; - :acetylcholine ; - :acetylcholine . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine - rdf:type owl:NamedIndividual , - ; - :ataxia ; - :ataxia ; - :hyperactivity ; - :hyperactivity ; - :paralysis ; - :paralysis . - -### http://www.co-ode.org/ontologies/ont.owl#ataxia - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#hyperactivity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#paralysis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + , , ; + , , ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "Acetylcholinesterase Inhibition leading to Acute Mortality via Impaired Coordination & Movementā€‹"^^ . diff --git a/models/AOP_315.ttl b/models/AOP_315.ttl index 6a4be353..6e677b07 100644 --- a/models/AOP_315.ttl +++ b/models/AOP_315.ttl @@ -1,114 +1,69 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Activation, LXR"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000009198 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051098 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001933 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006470 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032993 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0043392 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001391 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032633 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002286 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#tyrosine-protein%20kinase%20JAK3 - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20binding ; - :regulation%20of%20binding ; - :regulation%20of%20binding ; - :regulation%20of%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20binding - rdf:type owl:NamedIndividual , - ; - :protein%20dephosphorylation . - -### http://www.co-ode.org/ontologies/ont.owl#signal%20transducer%20and%20transcription%20activator%20STAT - rdf:type owl:NamedIndividual , - ; - :protein%20dephosphorylation ; - :protein%20dephosphorylation ; - :protein%20dephosphorylation ; - :protein%20dephosphorylation . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20dephosphorylation - rdf:type owl:NamedIndividual , - ; - :negative%20regulation%20of%20DNA%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#protein-DNA%20complex - rdf:type owl:NamedIndividual , - ; - :negative%20regulation%20of%20DNA%20binding ; - :negative%20regulation%20of%20DNA%20binding ; - :negative%20regulation%20of%20DNA%20binding ; - :negative%20regulation%20of%20DNA%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#negative%20regulation%20of%20DNA%20binding - rdf:type owl:NamedIndividual , - ; - :interleukin-4%20production . - -### http://www.co-ode.org/ontologies/ont.owl#interleukin-4 - rdf:type owl:NamedIndividual , - ; - :interleukin-4%20production . - -### http://www.co-ode.org/ontologies/ont.owl#interleukin-4%20production - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation%20involved%20in%20immune%20response . - -### http://www.co-ode.org/ontologies/ont.owl#T%20cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - . - + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Inhibition of JAK3 leading to impairment of T-Cell Dependent Antibody Response"^^ . diff --git a/models/AOP_318.ttl b/models/AOP_318.ttl index 90509790..23284fb4 100644 --- a/models/AOP_318.ttl +++ b/models/AOP_318.ttl @@ -1,84 +1,54 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Accumulation, Fatty acid"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000011406 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004883 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_35366 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006635 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17855 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor - rdf:type owl:NamedIndividual , - ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20beta-oxidation - rdf:type owl:NamedIndividual , - ; - :triglyceride ; - :triglyceride ; - :triglyceride ; - :triglyceride . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "Glucocorticoid Receptor activation leading to hepatic steatosis"^^ . diff --git a/models/AOP_319.ttl b/models/AOP_319.ttl index 3651bb28..ac7d6770 100644 --- a/models/AOP_319.ttl +++ b/models/AOP_319.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Up Regulation, Acetyl-CoA carboxylase-1 (ACC-1)"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_3815 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0032964 - rdf:type owl:Class . + a . + ; + a , . + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#collagen - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#collagen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Binding to ACE2 leading to lung fibrosis"^^ . diff --git a/models/AOP_32.ttl b/models/AOP_32.ttl index 60392812..2832762f 100644 --- a/models/AOP_32.ttl +++ b/models/AOP_32.ttl @@ -1,130 +1,87 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "irregularities, ovarian cycle"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_39185 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008152 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_25212 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/HP_0001410 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000011326 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004517 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MI_2141 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072574 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thiamethoxam - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#metabolic%20process - rdf:type owl:NamedIndividual , - ; - :Decreased%20liver%20function . - -### http://www.co-ode.org/ontologies/ont.owl#metabolite - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#metabolic%20process - rdf:type owl:NamedIndividual , - ; - :Decreased%20liver%20function . - -### http://www.co-ode.org/ontologies/ont.owl#Decreased%20liver%20function - rdf:type owl:NamedIndividual , - ; - :nitric-oxide%20synthase%20activity ; - :nitric-oxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#nitric%20oxide%20synthase%2C%20brain - rdf:type owl:NamedIndividual , - ; - :nitric-oxide%20synthase%20activity ; - :nitric-oxide%20synthase%20activity ; - :nitric-oxide%20synthase%20activity ; - :nitric-oxide%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#nitric-oxide%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :hepatotoxicity . - -### http://www.co-ode.org/ontologies/ont.owl#hepatotoxicity - rdf:type owl:NamedIndividual , - ; - :hepatocyte%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte%20proliferation - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Inhibition of iNOS, hepatotoxicity, and regenerative proliferation leading to liver tumors"^^ . diff --git a/models/AOP_320.ttl b/models/AOP_320.ttl index 5f9a5502..a457d8f0 100644 --- a/models/AOP_320.ttl +++ b/models/AOP_320.ttl @@ -1,145 +1,74 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, FA Influx"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0031381 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039694 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039690 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0072516 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019074 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019024 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019081 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#endocytosis%20involved%20in%20viral%20entry%20into%20host%20cell - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#protease%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#neuropilin%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20replication - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#positive%20stranded%20viral%20RNA%20replication - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20assembly%20compartment - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging . + a . -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20packaging - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription . + a , . -### http://www.co-ode.org/ontologies/ont.owl#mRNA%20transcription - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation . + a . -### http://www.co-ode.org/ontologies/ont.owl#viral%20translation - rdf:type owl:NamedIndividual , - . + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a , . + + a , . + + a , . + + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "Binding of SARS-CoV-2 to ACE2 receptor leading to acute respiratory distress associated mortality"^^ . diff --git a/models/AOP_322.ttl b/models/AOP_322.ttl index 42da4e1f..210e0acd 100644 --- a/models/AOP_322.ttl +++ b/models/AOP_322.ttl @@ -1,68 +1,33 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, PXR/SXR"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006305 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20alkylation ; - :DNA%20alkylation ; - :DNA%20alkylation ; - :DNA%20alkylation . + a . -### http://www.co-ode.org/ontologies/ont.owl#DNA%20alkylation - rdf:type owl:NamedIndividual , - ; - :DNA%20repair . + , ; + , ; + , ; + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - . + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Alkylation of DNA leading to reduced sperm count"^^ . diff --git a/models/AOP_323.ttl b/models/AOP_323.ttl index 376f7a9d..11416b4b 100644 --- a/models/AOP_323.ttl +++ b/models/AOP_323.ttl @@ -1,138 +1,81 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increased, Liver Steatosis"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_16113 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0006695 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030301 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17002 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_34133 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006702 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/FMA_67338 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/HP_0008669 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20alpha - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :cholesterol%20biosynthetic%20process ; - :cholesterol%20transport ; - :cholesterol%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol - rdf:type owl:NamedIndividual , - ; - :cholesterol%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :androgen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol - rdf:type owl:NamedIndividual , - ; - :cholesterol%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol%20transport - rdf:type owl:NamedIndividual , - ; - :androgen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#cholesteryl%20ester - rdf:type owl:NamedIndividual , - ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport ; - :cholesterol%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#cholesterol%20transport - rdf:type owl:NamedIndividual , - ; - :androgen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#11-Keto-testosterone - rdf:type owl:NamedIndividual , - ; - :androgen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :Abnormal%20spermatogenesis . - -### http://www.co-ode.org/ontologies/ont.owl#Mature%20sperm%20cell - rdf:type owl:NamedIndividual , - ; - :Abnormal%20spermatogenesis ; - :Abnormal%20spermatogenesis . + a . -### http://www.co-ode.org/ontologies/ont.owl#Abnormal%20spermatogenesis - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a , . + + ; + a , . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + "development"^^ ; + a ; + "PPARalpha Agonism Leading to Decreased Viable Offspring via Decreased 11-Ketotestosterone"^^ . diff --git a/models/AOP_324.ttl b/models/AOP_324.ttl index 36c3ad6e..295f5fb5 100644 --- a/models/AOP_324.ttl +++ b/models/AOP_324.ttl @@ -1,69 +1,33 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, FoxA2"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Thermal stress leading to population decline (1)"^^ . diff --git a/models/AOP_325.ttl b/models/AOP_325.ttl index cb1181a6..b3c78972 100644 --- a/models/AOP_325.ttl +++ b/models/AOP_325.ttl @@ -1,52 +1,21 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, Mitochondrial fatty acid beta-oxidation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . + ; + a , . + a . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Thermal stress leading to population decline (2)"^^ . diff --git a/models/AOP_326.ttl b/models/AOP_326.ttl index 68db3a92..6cd98791 100644 --- a/models/AOP_326.ttl +++ b/models/AOP_326.ttl @@ -1,69 +1,33 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Down Regulation, CPT1A"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Thermal stress leading to population decline (3)"^^ . diff --git a/models/AOP_327.ttl b/models/AOP_327.ttl index 678a8290..d191e6d1 100644 --- a/models/AOP_327.ttl +++ b/models/AOP_327.ttl @@ -1,52 +1,21 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Down Regulation, HMGCS2"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + ; + a , . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Excessive reactive oxygen species production leading to mortality (1)"^^ . diff --git a/models/AOP_328.ttl b/models/AOP_328.ttl index 9616c1b6..ed29d480 100644 --- a/models/AOP_328.ttl +++ b/models/AOP_328.ttl @@ -1,63 +1,28 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Up Regulation, SCD-1"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Excessive reactive oxygen species production leading to mortality (2)"^^ . diff --git a/models/AOP_329.ttl b/models/AOP_329.ttl index 80813020..6baa075b 100644 --- a/models/AOP_329.ttl +++ b/models/AOP_329.ttl @@ -1,63 +1,28 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Up Regulation, CD36"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Excessive reactive oxygen species production leading to mortality (3)"^^ . diff --git a/models/AOP_33.ttl b/models/AOP_33.ttl index 4846fad0..a93b0734 100644 --- a/models/AOP_33.ttl +++ b/models/AOP_33.ttl @@ -1,42 +1,20 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "reduction in ovarian granulosa cells, Aromatase (Cyp19a1)"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000001168 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003606 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Kidney toxicity induced by activation of 5HT2C"^^ . diff --git a/models/AOP_330.ttl b/models/AOP_330.ttl index 3068a21b..755ff95e 100644 --- a/models/AOP_330.ttl +++ b/models/AOP_330.ttl @@ -1,48 +1,19 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, FA Influx"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + ; + a , . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Excessive reactive oxygen species production leading to mortality (4)"^^ . diff --git a/models/AOP_331.ttl b/models/AOP_331.ttl index b89037da..cb0b2c61 100644 --- a/models/AOP_331.ttl +++ b/models/AOP_331.ttl @@ -1,32 +1,8 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, Ketogenesis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# + a . + "development"^^ ; + a ; + "Formation of DNA photoproducts leading to growth inhibition (1)"^^ . diff --git a/models/AOP_334.ttl b/models/AOP_334.ttl index b40bc550..053caa85 100644 --- a/models/AOP_334.ttl +++ b/models/AOP_334.ttl @@ -1,131 +1,81 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Activation, NRF2"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000011406 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004883 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/PR_000030513 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048179 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032924 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000354 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0031101 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor - rdf:type owl:NamedIndividual , - ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#teratocarcinoma-derived%20growth%20factor%201 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :activin%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#activin%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :activin%20receptor%20signaling%20pathway ; - :activin%20receptor%20signaling%20pathway ; - :activin%20receptor%20signaling%20pathway ; - :activin%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#activin%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :fin%20regeneration . - -### http://www.co-ode.org/ontologies/ont.owl#blastemal%20cell - rdf:type owl:NamedIndividual , - ; - :fin%20regeneration . - -### http://www.co-ode.org/ontologies/ont.owl#fin%20regeneration - rdf:type owl:NamedIndividual , - ; - :aquatic%20locomotion . + a . -### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Glucocorticoid Receptor Agonism Leading to Impaired Fin Regeneration"^^ . diff --git a/models/AOP_335.ttl b/models/AOP_335.ttl index 365930d9..8f16f88a 100644 --- a/models/AOP_335.ttl +++ b/models/AOP_335.ttl @@ -1,73 +1,40 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, NR1H4"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000731 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . + a . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#urothelial%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . + a , . -### http://www.co-ode.org/ontologies/ont.owl#urothelial%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . + a , . -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - . + a . + ; + ; + ; + ; + ; + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "AOP for urothelial carcinogenesis due to chemical cytotoxicity by mitochondrial impairment "^^ . diff --git a/models/AOP_336.ttl b/models/AOP_336.ttl index fb6c80a9..559fd371 100644 --- a/models/AOP_336.ttl +++ b/models/AOP_336.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, SHP"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "DNA methyltransferase inhibition leading to population decline (1)"^^ . diff --git a/models/AOP_337.ttl b/models/AOP_337.ttl index 6eaca76f..40cb586f 100644 --- a/models/AOP_337.ttl +++ b/models/AOP_337.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, PPARĪ±"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "DNA methyltransferase inhibition leading to population decline (2)"^^ . diff --git a/models/AOP_338.ttl b/models/AOP_338.ttl index dd43a7cf..6602ac87 100644 --- a/models/AOP_338.ttl +++ b/models/AOP_338.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, DHB4/HSD17B4"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "DNA methyltransferase inhibition leading to population decline (3)"^^ . diff --git a/models/AOP_339.ttl b/models/AOP_339.ttl index 29d9b611..01701724 100644 --- a/models/AOP_339.ttl +++ b/models/AOP_339.ttl @@ -1,36 +1,12 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, Mitochondrial fatty acid beta-oxidation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . - - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "DNA methyltransferase inhibition leading to population decline (4)"^^ . diff --git a/models/AOP_34.ttl b/models/AOP_34.ttl index c5263857..485074e1 100644 --- a/models/AOP_34.ttl +++ b/models/AOP_34.ttl @@ -1,295 +1,147 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, Pregnane-X receptor, NR1l2"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000011394 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011395 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000001905 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_35366 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_2000193 - rdf:type owl:Class . + , ; + a , . -### http://purl.obolibrary.org/obo/PR_000010460 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000015611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032933 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007348 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004312 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000014497 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006633 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17855 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0061726 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005234 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013058 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#oxysterols%20receptor%20LXR-beta - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#oxysterols%20receptor%20LXR-alpha - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#platelet%20glycoprotein%204 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :positive%20regulation%20of%20fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :positive%20regulation%20of%20fatty%20acid%20transport ; - :positive%20regulation%20of%20fatty%20acid%20transport ; - :positive%20regulation%20of%20fatty%20acid%20transport ; - :positive%20regulation%20of%20fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#positive%20regulation%20of%20fatty%20acid%20transport - rdf:type owl:NamedIndividual , - ; - :triglyceride ; - :triglyceride ; - :triglyceride ; - :triglyceride . - -### http://www.co-ode.org/ontologies/ont.owl#carbohydrate-responsive%20element-binding%20protein - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#sterol%20regulatory%20element-binding%20protein%201 - rdf:type owl:NamedIndividual , - ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#SREBP%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20synthase - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20synthase%20activity ; - :fatty%20acid%20synthase%20activity ; - :fatty%20acid%20synthase%20activity ; - :fatty%20acid%20synthase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#acyl-CoA%20desaturase - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :triglyceride ; - :triglyceride ; - :triglyceride ; - :triglyceride . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :triglyceride ; - :triglyceride ; - :triglyceride ; - :triglyceride . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :triglyceride ; - :triglyceride ; - :triglyceride ; - :triglyceride . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :triglyceride ; - :triglyceride ; - :triglyceride ; - :triglyceride . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :mitochondrion%20disassembly ; - :mitochondrion%20disassembly ; - :mitochondrion%20disassembly ; - :mitochondrion%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :mitochondrion%20disassembly ; - :mitochondrion%20disassembly ; - :mitochondrion%20disassembly ; - :mitochondrion%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :mitochondrion%20disassembly . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion%20disassembly - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#platelet%20glycoprotein%204 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :positive%20regulation%20of%20fatty%20acid%20transport . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + , ; + a , . + + a . + + a . + + ; + ; + , ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "LXR activation leading to hepatic steatosis"^^ . diff --git a/models/AOP_340.ttl b/models/AOP_340.ttl index 51787af8..c6076546 100644 --- a/models/AOP_340.ttl +++ b/models/AOP_340.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, LXR alpha"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "DNA methyltransferase inhibition leading to transgenerational effects (1)"^^ . diff --git a/models/AOP_341.ttl b/models/AOP_341.ttl index c8f87d60..7e1409ea 100644 --- a/models/AOP_341.ttl +++ b/models/AOP_341.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Liver Steatosis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "DNA methyltransferase inhibition leading to transgenerational effects (2)"^^ . diff --git a/models/AOP_342.ttl b/models/AOP_342.ttl index 8122595a..a5b81838 100644 --- a/models/AOP_342.ttl +++ b/models/AOP_342.ttl @@ -1,71 +1,36 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, SREBP1c"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0004100 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0001002 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042335 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/GO_0018990 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#chitin%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :cuticle%20development . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cuticle - rdf:type owl:NamedIndividual , - ; - :cuticle%20development . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cuticle%20development - rdf:type owl:NamedIndividual , - ; - :ecdysis%2C%20chitin-based%20cuticle . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ecdysis%2C%20chitin-based%20cuticle - rdf:type owl:NamedIndividual , - ; - :mortality . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "S-adenosylmethionine depletion leading to population decline (1)"^^ . diff --git a/models/AOP_343.ttl b/models/AOP_343.ttl index 7822bf25..54334b85 100644 --- a/models/AOP_343.ttl +++ b/models/AOP_343.ttl @@ -1,63 +1,31 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, MTTP"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/UBERON_0001002 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042335 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0018990 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#cuticle - rdf:type owl:NamedIndividual , - ; - :cuticle%20development . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cuticle%20development - rdf:type owl:NamedIndividual , - ; - :ecdysis%2C%20chitin-based%20cuticle . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ecdysis%2C%20chitin-based%20cuticle - rdf:type owl:NamedIndividual , - ; - :mortality . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "S-adenosylmethionine depletion leading to population decline (2)"^^ . diff --git a/models/AOP_344.ttl b/models/AOP_344.ttl index 2cce04d1..7bf6fc46 100644 --- a/models/AOP_344.ttl +++ b/models/AOP_344.ttl @@ -1,51 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, ApoB100"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - . + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Androgen receptor (AR) antagonism leading to nipple retention (NR) in male (mammalian) offspring"^^ . diff --git a/models/AOP_345.ttl b/models/AOP_345.ttl index 04283a16..bd579515 100644 --- a/models/AOP_345.ttl +++ b/models/AOP_345.ttl @@ -1,54 +1,28 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Triglyceride"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_1000294 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression . + a , . -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - . + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Androgen receptor (AR) antagonism leading to decreased fertility in females"^^ . diff --git a/models/AOP_346.ttl b/models/AOP_346.ttl index fec67f4f..2fa84765 100644 --- a/models/AOP_346.ttl +++ b/models/AOP_346.ttl @@ -1,107 +1,63 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, De Novo FA synthesis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000006100 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0070330 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006703 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_2005272 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008584 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/GO_0046661 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . + ; + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :male%20gonad%20development . + a . -### http://www.co-ode.org/ontologies/ont.owl#immature%20gonad - rdf:type owl:NamedIndividual , - ; - :male%20gonad%20development ; - :male%20gonad%20development ; - :male%20gonad%20development ; - :male%20gonad%20development . + a . -### http://www.co-ode.org/ontologies/ont.owl#male%20gonad%20development - rdf:type owl:NamedIndividual , - ; - :male%20sex%20differentiation . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :male%20sex%20differentiation ; - :male%20sex%20differentiation ; - :male%20sex%20differentiation ; - :male%20sex%20differentiation . + a . -### http://www.co-ode.org/ontologies/ont.owl#male%20sex%20differentiation - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + ; + a , . + ; + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aromatase inhibition leads to male-biased sex ratio via impacts on gonad differentiation"^^ . diff --git a/models/AOP_347.ttl b/models/AOP_347.ttl index 6ef1f2c5..171e6a6b 100644 --- a/models/AOP_347.ttl +++ b/models/AOP_347.ttl @@ -1,78 +1,34 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, AKT2"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D048031 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000000046 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#JNK%20Mitogen-Activated%20Protein%20Kinases - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#TGF-beta - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#TGF-beta - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Toll-like receptor 4 activation and peroxisome proliferator-activated receptor gamma inactivation leading to pulmonary fibrosis"^^ . diff --git a/models/AOP_348.ttl b/models/AOP_348.ttl index 9a8ac7c6..b5b2158f 100644 --- a/models/AOP_348.ttl +++ b/models/AOP_348.ttl @@ -1,92 +1,54 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Liver Steatosis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_34133 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006702 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/FMA_67338 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0008669 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#11-Keto-testosterone - rdf:type owl:NamedIndividual , - ; - :androgen%20biosynthetic%20process . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#androgen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :Abnormal%20spermatogenesis . + a . -### http://www.co-ode.org/ontologies/ont.owl#Mature%20sperm%20cell - rdf:type owl:NamedIndividual , - ; - :Abnormal%20spermatogenesis ; - :Abnormal%20spermatogenesis . + a . -### http://www.co-ode.org/ontologies/ont.owl#Abnormal%20spermatogenesis - rdf:type owl:NamedIndividual , - ; - :fertility ; - :fertility . + a . -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + ; + ; + a , . + ; + a , . + ; + ; + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of 11Ī²-Hydroxysteroid Dehydrogenase leading to decreased population trajectory "^^ . diff --git a/models/AOP_349.ttl b/models/AOP_349.ttl index 8e26088c..e3fc2c07 100644 --- a/models/AOP_349.ttl +++ b/models/AOP_349.ttl @@ -1,74 +1,33 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "systemic inflammation leading to hepatic steatosis"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_34133 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006702 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + ; + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#11-Keto-testosterone - rdf:type owl:NamedIndividual , - ; - :androgen%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#androgen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . + a , . -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of 11Ī²-hydroxylase leading to decresed population trajectory "^^ . diff --git a/models/AOP_35.ttl b/models/AOP_35.ttl index 0f4ff8d9..54d90f98 100644 --- a/models/AOP_35.ttl +++ b/models/AOP_35.ttl @@ -1,35 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Loss, Cochlear function"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0016020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005886 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# + a . + "review"^^ ; + a ; + "Narcosis leading to respiratory failure"^^ . diff --git a/models/AOP_358.ttl b/models/AOP_358.ttl index 39756be1..977c209d 100644 --- a/models/AOP_358.ttl +++ b/models/AOP_358.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased apoptosis, decreased number of adult Leydig Cells "^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0018990 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#ecdysis%2C%20chitin-based%20cuticle - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Chitinase inhibition leading to mortality"^^ . diff --git a/models/AOP_359.ttl b/models/AOP_359.ttl index 8e35e3f4..e3cbe848 100644 --- a/models/AOP_359.ttl +++ b/models/AOP_359.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Testosterone synthesis in Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0018990 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#ecdysis%2C%20chitin-based%20cuticle - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Chitobiase inhibition leading to mortality"^^ . diff --git a/models/AOP_36.ttl b/models/AOP_36.ttl index 051ae3da..54473be7 100644 --- a/models/AOP_36.ttl +++ b/models/AOP_36.ttl @@ -1,150 +1,75 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Thyroxine (T4) in neuronal tissue, Decreased "^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013057 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013058 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_35366 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000008774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006635 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003857 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20alpha - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#3-hydroxyacyl-CoA%20dehydrogenase%20type-2 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20beta-oxidation - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#3-hydroxyacyl-CoA%20dehydrogenase%20type-2 - rdf:type owl:NamedIndividual , - ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#3-hydroxyacyl-CoA%20dehydrogenase%20activity - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20beta-oxidation . - -### http://www.co-ode.org/ontologies/ont.owl#3-hydroxyacyl-CoA%20dehydrogenase%20type-2 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#3-hydroxyacyl-CoA%20dehydrogenase%20type-2 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :3-hydroxyacyl-CoA%20dehydrogenase%20activity . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + "development"^^ ; + a ; + "Peroxisomal Fatty Acid Beta-Oxidation Inhibition Leading to Steatosis"^^ . diff --git a/models/AOP_360.ttl b/models/AOP_360.ttl index 5705cbda..e4219d7a 100644 --- a/models/AOP_360.ttl +++ b/models/AOP_360.ttl @@ -1,71 +1,36 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, testosterone level"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0004100 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0001002 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042335 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/GO_0018990 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#chitin%20synthase%20activity - rdf:type owl:NamedIndividual , - ; - :cuticle%20development . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cuticle - rdf:type owl:NamedIndividual , - ; - :cuticle%20development . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cuticle%20development - rdf:type owl:NamedIndividual , - ; - :ecdysis%2C%20chitin-based%20cuticle . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ecdysis%2C%20chitin-based%20cuticle - rdf:type owl:NamedIndividual , - ; - :mortality . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Chitin synthase 1 inhibition leading to mortality"^^ . diff --git a/models/AOP_361.ttl b/models/AOP_361.ttl index 31e44385..b3026aee 100644 --- a/models/AOP_361.ttl +++ b/models/AOP_361.ttl @@ -1,63 +1,31 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased sperm quantity or quality in the adult, Decreased fertility "^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/UBERON_0001002 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042335 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0018990 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#cuticle - rdf:type owl:NamedIndividual , - ; - :cuticle%20development . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cuticle%20development - rdf:type owl:NamedIndividual , - ; - :ecdysis%2C%20chitin-based%20cuticle . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ecdysis%2C%20chitin-based%20cuticle - rdf:type owl:NamedIndividual , - ; - :mortality . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Sulfonylureareceptor binding leading to mortality"^^ . diff --git a/models/AOP_363.ttl b/models/AOP_363.ttl index aae9e5f1..b423385e 100644 --- a/models/AOP_363.ttl +++ b/models/AOP_363.ttl @@ -1,168 +1,111 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, Na+/I- symporter (NIS)"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000016584 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004447 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000966 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010842 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000970 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0002090 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase - rdf:type owl:NamedIndividual , - ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level - rdf:type owl:NamedIndividual , - ; - :retina%20layer%20formation ; - :retina%20layer%20formation . - -### http://www.co-ode.org/ontologies/ont.owl#retina - rdf:type owl:NamedIndividual , - ; - :retina%20layer%20formation . - -### http://www.co-ode.org/ontologies/ont.owl#retina%20layer%20formation - rdf:type owl:NamedIndividual , - ; - :vision%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#eye - rdf:type owl:NamedIndividual , - ; - :vision%20trait ; - :vision%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#vision%20trait - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + "review"^^ ; + a ; + "Thyroperoxidase inhibition leading to altered visual function via altered retinal layer structure"^^ . diff --git a/models/AOP_364.ttl b/models/AOP_364.ttl index b80a263c..fb35311f 100644 --- a/models/AOP_364.ttl +++ b/models/AOP_364.ttl @@ -1,165 +1,103 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Thyroid hormone synthesis, Decreased"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000016584 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004447 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000970 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001297 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_0002090 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase - rdf:type owl:NamedIndividual , - ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level - rdf:type owl:NamedIndividual , - ; - :microphthalmia ; - :microphthalmia . - -### http://www.co-ode.org/ontologies/ont.owl#eye - rdf:type owl:NamedIndividual , - ; - :microphthalmia ; - :microphthalmia . - -### http://www.co-ode.org/ontologies/ont.owl#microphthalmia - rdf:type owl:NamedIndividual , - ; - :vision%20trait ; - :vision%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#eye - rdf:type owl:NamedIndividual , - ; - :vision%20trait ; - :vision%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#vision%20trait - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + , ; + , ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + a . + + ; + ; + a , . + + "review"^^ ; + a ; + "Thyroperoxidase inhibition leading to altered visual function via decreased eye size"^^ . diff --git a/models/AOP_365.ttl b/models/AOP_365.ttl index 19d374db..ab2469a7 100644 --- a/models/AOP_365.ttl +++ b/models/AOP_365.ttl @@ -1,148 +1,95 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - " Thyroxine (T4) in serum, Decreased"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000016584 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004447 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_28774 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0005418 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000970 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_0002090 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase - rdf:type owl:NamedIndividual , - ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20hormone%20level ; - :abnormal%20circulating%20hormone%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#eye - rdf:type owl:NamedIndividual , - ; - :vision%20trait ; - :vision%20trait . + a . -### http://www.co-ode.org/ontologies/ont.owl#vision%20trait - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . + a . -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + a , . + + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + "development"^^ ; + a ; + "Thyroperoxidase inhibition leading to altered visual function via altered photoreceptor patterning"^^ . diff --git a/models/AOP_366.ttl b/models/AOP_366.ttl index e2fd9519..f1dece7c 100644 --- a/models/AOP_366.ttl +++ b/models/AOP_366.ttl @@ -1,127 +1,68 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Thyroxine (T4) in neuronal tissue, Decreased "^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000016801 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005488 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006810 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008152 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#transthyretin - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :transport ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :transport ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#transport - rdf:type owl:NamedIndividual , - ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#metabolic%20process - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + , ; + , ; + , ; + , ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "Competitive binding to thyroid hormone carrier protein transthyretin (TTR) leading to altered amphibian metamorphosis "^^ . diff --git a/models/AOP_367.ttl b/models/AOP_367.ttl index e24333e9..b215949b 100644 --- a/models/AOP_367.ttl +++ b/models/AOP_367.ttl @@ -1,95 +1,51 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Altered, Neuroanatomy"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006810 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007552 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008152 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :transport ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :transport ; - :transport ; - :transport ; - :transport . - -### http://www.co-ode.org/ontologies/ont.owl#transport - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + a . + + "development"^^ ; + a ; + "Competitive binding to thyroid hormone carrier protein thyroid binding globulin (TBG) leading to altered amphibian metamorphosis"^^ . diff --git a/models/AOP_368.ttl b/models/AOP_368.ttl index 7c57ac9a..3be74d76 100644 --- a/models/AOP_368.ttl +++ b/models/AOP_368.ttl @@ -1,37 +1,14 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Altered, Neurophysiology"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/UBERON_0005386 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0002006 - rdf:type owl:Class . + a . + a . - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Cytochrome oxidase inhibition leading to olfactory nasal lesions"^^ . diff --git a/models/AOP_37.ttl b/models/AOP_37.ttl index f478cfb6..20ff396d 100644 --- a/models/AOP_37.ttl +++ b/models/AOP_37.ttl @@ -1,111 +1,62 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - " Thyroxine (T4) in serum, Decreased"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000182 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0072574 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D000236 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D002277 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . + a , . + a , . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20alpha - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#mitogenic%20signaling%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte - rdf:type owl:NamedIndividual , - ; - :hepatocyte%20proliferation . + a . -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte%20proliferation - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#Carcinoma - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#Adenoma - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "PPARĪ± activation leading to hepatocellular adenomas and carcinomas in rodents"^^ . diff --git a/models/AOP_374.ttl b/models/AOP_374.ttl index cb2175c0..95162153 100644 --- a/models/AOP_374.ttl +++ b/models/AOP_374.ttl @@ -1,67 +1,30 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased number and function of adult Leydig cells, Decreased COUP-TFII stem Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CL_0000129 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001847 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000127 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0002229 - rdf:type owl:Class . + a . + a . + ; + ; + a , . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#astrocyte - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#neurodegeneration - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Binding of Sars-CoV-2 spike protein to ACE 2 receptors expressed on brain cells (neuronal and non-neuronal) leads to neuroinflammation resulting in encephalitis"^^ . diff --git a/models/AOP_376.ttl b/models/AOP_376.ttl index 947a9458..6fdeb098 100644 --- a/models/AOP_376.ttl +++ b/models/AOP_376.ttl @@ -1,104 +1,62 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased sperm quantity / quality in the adult, Decreased fertility "^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000004191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004882 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_2005272 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008584 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046661 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor - rdf:type owl:NamedIndividual , - ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity ; - :androgen%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :male%20gonad%20development . - -### http://www.co-ode.org/ontologies/ont.owl#immature%20gonad - rdf:type owl:NamedIndividual , - ; - :male%20gonad%20development ; - :male%20gonad%20development ; - :male%20gonad%20development ; - :male%20gonad%20development . - -### http://www.co-ode.org/ontologies/ont.owl#male%20gonad%20development - rdf:type owl:NamedIndividual , - ; - :male%20sex%20differentiation . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :male%20sex%20differentiation ; - :male%20sex%20differentiation ; - :male%20sex%20differentiation ; - :male%20sex%20differentiation . - -### http://www.co-ode.org/ontologies/ont.owl#male%20sex%20differentiation - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + a . + + ; + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Androgen receptor agonism leading to male-biased sex ratio"^^ . diff --git a/models/AOP_377.ttl b/models/AOP_377.ttl index e65b0bfd..360702ff 100644 --- a/models/AOP_377.ttl +++ b/models/AOP_377.ttl @@ -1,117 +1,70 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased testosterone by the fetal Leydig cells, Increased estradiol"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0072559 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0044546 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0034599 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0000302 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + ; + ; + ; + ; + a , . -### http://purl.obolibrary.org/obo/GO_0002526 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/FMA_84050 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0050663 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003606 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0002113 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/Q000633 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0043122 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001860 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#NLRP3%20inflammasome%20complex - rdf:type owl:NamedIndividual , - ; - :NLRP3%20inflammasome%20complex%20assembly ; - :NLRP3%20inflammasome%20complex%20assembly ; - :NLRP3%20inflammasome%20complex%20assembly ; - :NLRP3%20inflammasome%20complex%20assembly . + a . -### http://www.co-ode.org/ontologies/ont.owl#NLRP3%20inflammasome%20complex%20assembly - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20I-kappaB%20kinase/NF-kappaB%20signaling - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#Cytokine - rdf:type owl:NamedIndividual , - ; - :cytokine%20secretion ; - :cytokine%20secretion ; - :cytokine%20secretion ; - :cytokine%20secretion . + a , . -### http://www.co-ode.org/ontologies/ont.owl#cytokine%20secretion - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#acute%20inflammatory%20response - rdf:type owl:NamedIndividual , - . + a , . + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Dysregulated prolonged Toll Like Receptor 9 (TLR9) activation leading to Multi Organ Failure involving Acute Respiratory Distress Syndrome (ARDS)"^^ . diff --git a/models/AOP_379.ttl b/models/AOP_379.ttl index 3aaf1d44..fcfea9be 100644 --- a/models/AOP_379.ttl +++ b/models/AOP_379.ttl @@ -1,224 +1,107 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased testosterone by the fetal Leydig cells, Increased COUP-TFII in fetal Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CL_0000233 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0004936 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0031381 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0039694 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039690 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072516 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019074 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019024 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019081 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0034599 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000302 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#endocytosis%20involved%20in%20viral%20entry%20into%20host%20cell - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#protease%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#neuropilin%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20replication - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#positive%20stranded%20viral%20RNA%20replication - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20assembly%20compartment - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20packaging - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription . - -### http://www.co-ode.org/ontologies/ont.owl#mRNA%20transcription - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20translation - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress . - -### http://www.co-ode.org/ontologies/ont.owl#cellular%20response%20to%20oxidative%20stress - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#response%20to%20reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress . - -### http://www.co-ode.org/ontologies/ont.owl#cellular%20response%20to%20oxidative%20stress - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#response%20to%20reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#platelet - rdf:type owl:NamedIndividual , - ; - :Venous%20thrombosis ; - :Venous%20thrombosis . - -### http://www.co-ode.org/ontologies/ont.owl#Venous%20thrombosis - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + , ; + a , . + + a , . + + , ; + a , . + + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + , ; + a , . + + , ; + a , . + + , ; + a , . + + a . + + a , . + + a . + + a . + + a . + + ; + ; + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "Binding to ACE2 leading to thrombosis and disseminated intravascular coagulation"^^ . diff --git a/models/AOP_38.ttl b/models/AOP_38.ttl index 9845e239..af10a989 100644 --- a/models/AOP_38.ttl +++ b/models/AOP_38.ttl @@ -1,119 +1,73 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Induction, Upregulation of glucuronyltransferase activity"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/UBERON_0002107 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003333 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008213 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000632 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035733 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_3815 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0032964 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002263 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0002526 - rdf:type owl:Class . + ; + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#protein%20alkylation - rdf:type owl:NamedIndividual , - ; - :cell%20death . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :cell%20activation%20involved%20in%20immune%20response . + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response - rdf:type owl:NamedIndividual , - ; - :acute%20inflammatory%20response . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#acute%20inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :hepatic%20stellate%20cell%20activation . + a . -### http://www.co-ode.org/ontologies/ont.owl#hepatic%20stellate%20cell - rdf:type owl:NamedIndividual , - ; - :hepatic%20stellate%20cell%20activation ; - :hepatic%20stellate%20cell%20activation ; - :hepatic%20stellate%20cell%20activation ; - :hepatic%20stellate%20cell%20activation . + a . -### http://www.co-ode.org/ontologies/ont.owl#hepatic%20stellate%20cell%20activation - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#collagen - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#collagen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis . + a . -### http://www.co-ode.org/ontologies/ont.owl#liver - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis ; - :liver%20fibrosis . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#liver%20fibrosis - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . + ; + a , . + ; + ; + a , . -################################################################# -# Object Statements -################################################################# + a , . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Protein Alkylation leading to Liver Fibrosis"^^ . diff --git a/models/AOP_382.ttl b/models/AOP_382.ttl index 11e12f59..1a0592ce 100644 --- a/models/AOP_382.ttl +++ b/models/AOP_382.ttl @@ -1,66 +1,35 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased sperm quantity / quality in the adult, Decreased fertility "^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_3815 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0032964 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0043122 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . + ; + ; + ; + ; + a , . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :regulation%20of%20I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :regulation%20of%20I-kappaB%20kinase%2FNF-kappaB%20signaling ; - :regulation%20of%20I-kappaB%20kinase%2FNF-kappaB%20signaling . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20I-kappaB%20kinase/NF-kappaB%20signaling - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#collagen - rdf:type owl:NamedIndividual , - ; - :collagen%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#collagen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Angiotensin II type 1 receptor (AT1R) agonism leading to lung fibrosis"^^ . diff --git a/models/AOP_383.ttl b/models/AOP_383.ttl index 15027f9b..f66d8e21 100644 --- a/models/AOP_383.ttl +++ b/models/AOP_383.ttl @@ -1,54 +1,24 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased testosterone by the fetal Leydig cells, Alterations in the fetal testis proteome"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/UBERON_0002107 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/MP_0003333 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#liver - rdf:type owl:NamedIndividual , - ; - :liver%20fibrosis ; - :liver%20fibrosis . - -### http://www.co-ode.org/ontologies/ont.owl#liver%20fibrosis - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of Angiotensin-converting enzyme 2 leading to liver fibrosis"^^ . diff --git a/models/AOP_384.ttl b/models/AOP_384.ttl index a702b4c7..13131ac6 100644 --- a/models/AOP_384.ttl +++ b/models/AOP_384.ttl @@ -1,36 +1,10 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased testosterone by the fetal Leydig cells, Increased COUP-TFII in fetal Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# + a , . + "development"^^ ; + a ; + "Hyperactivation of ACE/Ang-II/AT1R axis leading to chronic kidney disease "^^ . diff --git a/models/AOP_385.ttl b/models/AOP_385.ttl index 75aa8ec8..86b06623 100644 --- a/models/AOP_385.ttl +++ b/models/AOP_385.ttl @@ -1,85 +1,34 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased testosterone by the fetal Leydig cells, Dysgenesis of fetal Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003622 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004180 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0034394 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#angiotensin-converting%20enzyme%202 - rdf:type owl:NamedIndividual , - ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription . + a . -### http://www.co-ode.org/ontologies/ont.owl#mRNA%20transcription - rdf:type owl:NamedIndividual , - . + , , ; + , , ; + , , ; + , , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#angiotensin-converting%20enzyme%202 - rdf:type owl:NamedIndividual , - ; - :carboxypeptidase%20activity ; - :carboxypeptidase%20activity ; - :carboxypeptidase%20activity ; - :carboxypeptidase%20activity . + a , . -### http://www.co-ode.org/ontologies/ont.owl#carboxypeptidase%20activity - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#angiotensin-converting%20enzyme%202 - rdf:type owl:NamedIndividual , - ; - :protein%20localization%20to%20cell%20surface ; - :protein%20localization%20to%20cell%20surface ; - :protein%20localization%20to%20cell%20surface ; - :protein%20localization%20to%20cell%20surface . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20localization%20to%20cell%20surface - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#angiotensin-converting%20enzyme%202 - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Viral spike protein interaction with ACE2 leads to microvascular dysfunction, via ACE2 dysregulation"^^ . diff --git a/models/AOP_386.ttl b/models/AOP_386.ttl index bde6157d..a5a8b57b 100644 --- a/models/AOP_386.ttl +++ b/models/AOP_386.ttl @@ -1,52 +1,23 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased number and function of adult Leydig cells, Decreased COUP-TFII stem Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of ionizing energy leading to population decline via inhibition of photosynthesis"^^ . diff --git a/models/AOP_387.ttl b/models/AOP_387.ttl index 220ae6bb..50294789 100644 --- a/models/AOP_387.ttl +++ b/models/AOP_387.ttl @@ -1,67 +1,32 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased Cholesterol, Decreased De Novo Biosynthesis of Choleseterol"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_15422 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006754 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_1903409 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#ATP - rdf:type owl:NamedIndividual , - ; - :ATP%20biosynthetic%20process . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of ionising energy leading to population decline via mitochondrial dysfunction"^^ . diff --git a/models/AOP_388.ttl b/models/AOP_388.ttl index 5cf8c8bc..9be2fcf2 100644 --- a/models/AOP_388.ttl +++ b/models/AOP_388.ttl @@ -1,52 +1,21 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased Cholesterol, Decreased Uptake of Lipoproteins"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . + ; + a , . + a . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of ionising energy leading to population decline via programmed cell death"^^ . diff --git a/models/AOP_389.ttl b/models/AOP_389.ttl index 6961aae9..4618d62d 100644 --- a/models/AOP_389.ttl +++ b/models/AOP_389.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased Cholesterol, Decreased Transport of Cholesterol to the Inner Mitochondrial Membrane"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Oxygen-evolving complex damage leading to population decline via inhibition of photosynthesis"^^ . diff --git a/models/AOP_39.ttl b/models/AOP_39.ttl index 7ba75629..59d77117 100644 --- a/models/AOP_39.ttl +++ b/models/AOP_39.ttl @@ -1,180 +1,96 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Hippocampal anatomy, Altered "^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/FMA_241981 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008009 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/FMA_84050 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005125 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D012130 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001775 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002396 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000084 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0042110 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000813 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_59739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005515 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#electrophilic%20reagant - rdf:type owl:NamedIndividual , - ; - :protein%20binding ; - :protein%20binding ; - :protein%20binding ; - :protein%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Chemokine - rdf:type owl:NamedIndividual , - ; - :chemokine%20activity ; - :chemokine%20activity ; - :chemokine%20activity ; - :chemokine%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#chemokine%20activity - rdf:type owl:NamedIndividual , - ; - :cell%20activation ; - :MHC%20protein%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#Cytokine - rdf:type owl:NamedIndividual , - ; - :cytokine%20activity ; - :cytokine%20activity ; - :cytokine%20activity ; - :cytokine%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#cytokine%20activity - rdf:type owl:NamedIndividual , - ; - :cell%20activation ; - :MHC%20protein%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#MHC%20protein%20complex%20assembly - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#MHC%20protein%20complex%20assembly - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#T%20cell - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :T%20cell%20activation ; - :T%20cell%20activation ; - :T%20cell%20activation . - -### http://www.co-ode.org/ontologies/ont.owl#T%20cell%20activation - rdf:type owl:NamedIndividual , - ; - :Respiratory%20Hypersensitivity . - -### http://www.co-ode.org/ontologies/ont.owl#memory%20T%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :Respiratory%20Hypersensitivity . - -### http://www.co-ode.org/ontologies/ont.owl#Respiratory%20Hypersensitivity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#MHC%20protein%20complex%20assembly - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + , ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + "development"^^ ; + a ; + "Covalent Binding, Protein, leading to Increase, Allergic Respiratory Hypersensitivity Response"^^ . diff --git a/models/AOP_392.ttl b/models/AOP_392.ttl index fc749739..df0ff6c1 100644 --- a/models/AOP_392.ttl +++ b/models/AOP_392.ttl @@ -1,86 +1,34 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased sperm quantity or quality in the adult, Decreased fertility "^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0051918 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030195 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0003070 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001863 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + ; + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#negative%20regulation%20of%20fibrinolysis - rdf:type owl:NamedIndividual , - ; - :increased%20vascular%20permeability ; - :vasodilation ; - :vascular%20inflammation . + ; + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#negative%20regulation%20of%20blood%20coagulation - rdf:type owl:NamedIndividual , - ; - :increased%20vascular%20permeability ; - :vasodilation ; - :vascular%20inflammation . + a , . -### http://www.co-ode.org/ontologies/ont.owl#increased%20vascular%20permeability - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#vasodilation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#vascular%20inflammation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#negative%20regulation%20of%20fibrinolysis - rdf:type owl:NamedIndividual , - ; - :increased%20vascular%20permeability ; - :vasodilation ; - :vascular%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#negative%20regulation%20of%20blood%20coagulation - rdf:type owl:NamedIndividual , - ; - :increased%20vascular%20permeability ; - :vasodilation ; - :vascular%20inflammation . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Decreased fibrinolysis and activated bradykinin system leading to hyperinflammation"^^ . diff --git a/models/AOP_394.ttl b/models/AOP_394.ttl index 4fe77b58..a8a5f5a3 100644 --- a/models/AOP_394.ttl +++ b/models/AOP_394.ttl @@ -1,50 +1,18 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased steroidogenesis, Decreased Activity of Steroidogenic Enzymes in Adult Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . + a , . + a , . + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#endocytosis%20involved%20in%20viral%20entry%20into%20host%20cell - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#protease%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#neuropilin%20binding - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - + "development"^^ ; + a ; + "SARS-CoV-2 infection of olfactory epithelium leading to impaired olfactory function (short-term anosmia)"^^ . diff --git a/models/AOP_395.ttl b/models/AOP_395.ttl index d601d693..427e1735 100644 --- a/models/AOP_395.ttl +++ b/models/AOP_395.ttl @@ -1,46 +1,20 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased steroidogenesis, Increased Apoptosis of Adult Leydig Cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000233 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0004936 - rdf:type owl:Class . + a . + a . - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Binding of Sars-CoV-2 spike protein to ACE 2 receptors expressed on pericytes leads to disseminated intravascular coagulation resulting in cerebrovascular disease (stroke)"^^ . diff --git a/models/AOP_396.ttl b/models/AOP_396.ttl index e6661786..b1f6bfe5 100644 --- a/models/AOP_396.ttl +++ b/models/AOP_396.ttl @@ -1,81 +1,39 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased steroidogenesis, Alterations in the Leydig Cell Cytoskeleton"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . + ; + ; + a , . -### http://purl.obolibrary.org/obo/MP_0003674 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005694 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0051305 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a , . + a . + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :oxidative%20stress ; - :oxidative%20stress . + a , . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#oxidative%20stress - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#chromosome - rdf:type owl:NamedIndividual , - ; - :chromosome%20movement%20towards%20spindle%20pole . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#chromosome%20movement%20towards%20spindle%20pole - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Deposition of ionizing energy leads to population decline via impaired meiosis"^^ . diff --git a/models/AOP_397.ttl b/models/AOP_397.ttl index bca4ab17..4c365ecc 100644 --- a/models/AOP_397.ttl +++ b/models/AOP_397.ttl @@ -1,74 +1,36 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Apoptosis of adult Leydig cells, Decreased testosterone by adult Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16991 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . + a . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . + ; + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - ; - :mutation . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :mutation . + a . -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - . + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Bulky DNA adducts leading to mutations"^^ . diff --git a/models/AOP_398.ttl b/models/AOP_398.ttl index 4020d411..3286cbf7 100644 --- a/models/AOP_398.ttl +++ b/models/AOP_398.ttl @@ -1,45 +1,17 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased sperm quantity or quality in the adult, Decreased fertility "^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042698 - rdf:type owl:Class . + a , . + a . + ; + a , . -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#ovulation%20cycle - rdf:type owl:NamedIndividual , - ; - :fertility . - -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Inhibition of ALDH1A (RALDH) leading to impaired fertility via disrupted meiotic initiation of fetal oogonia of the ovary"^^ . diff --git a/models/AOP_399.ttl b/models/AOP_399.ttl index c97b32dd..15eac89d 100644 --- a/models/AOP_399.ttl +++ b/models/AOP_399.ttl @@ -1,128 +1,78 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Stimulation of adult Leydig cells via the Adrenal Corticosterone, Increased Glucocorticoid"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# -### http://purl.obolibrary.org/obo/PR_Q6EWH2 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004713 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0005623 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0000970 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001297 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_0002090 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#tyrosine-protein%20kinase%20fyna%20%28zebrafish%29 - rdf:type owl:NamedIndividual , - ; - :protein%20tyrosine%20kinase%20activity ; - :protein%20tyrosine%20kinase%20activity ; - :protein%20tyrosine%20kinase%20activity ; - :protein%20tyrosine%20kinase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20tyrosine%20kinase%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :microphthalmia . - -### http://www.co-ode.org/ontologies/ont.owl#eye - rdf:type owl:NamedIndividual , - ; - :microphthalmia ; - :microphthalmia . - -### http://www.co-ode.org/ontologies/ont.owl#microphthalmia - rdf:type owl:NamedIndividual , - ; - :vision%20trait ; - :vision%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#eye - rdf:type owl:NamedIndividual , - ; - :vision%20trait ; - :vision%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#vision%20trait - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + ; + a , . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + , ; + , ; + a , . + + ; + ; + a , . + + a . + + ; + ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "Inhibition of Fyna leading to increased mortality via decreased eye size (Microphthalmos)"^^ . diff --git a/models/AOP_4.ttl b/models/AOP_4.ttl index 5b1c27dc..653c10b8 100644 --- a/models/AOP_4.ttl +++ b/models/AOP_4.ttl @@ -1,174 +1,107 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, NADH-ubiquinone oxidoreductase (complex I)"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0008230 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0035076 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008255 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17029 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006031 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006936 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/C061375 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_P33244 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_Q9VCW0 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002790 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000100 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019226 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060079 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#ecdysone%20receptor%20holocomplex - rdf:type owl:NamedIndividual , - ; - :ecdysone%20receptor-mediated%20signaling%20pathway ; - :ecdysone%20receptor-mediated%20signaling%20pathway ; - :ecdysone%20receptor-mediated%20signaling%20pathway ; - :ecdysone%20receptor-mediated%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#ecdysone%20receptor-mediated%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#Eip75B%20protein%2C%20Drosophila - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#nuclear%20hormone%20receptor%20FTZ-F1%20%28fruit%20fly%29 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :ecdysis-triggering%20hormone%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#ecdysis-triggering%20hormone%20activity - rdf:type owl:NamedIndividual , - ; - :peptide%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#cardioactive%20peptide%20%28fruit%20fly%29 - rdf:type owl:NamedIndividual , - ; - :peptide%20secretion ; - :peptide%20secretion ; - :peptide%20secretion ; - :peptide%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#peptide%20secretion - rdf:type owl:NamedIndividual , - ; - :transmission%20of%20nerve%20impulse . - -### http://www.co-ode.org/ontologies/ont.owl#motor%20neuron - rdf:type owl:NamedIndividual , - ; - :transmission%20of%20nerve%20impulse ; - :transmission%20of%20nerve%20impulse ; - :transmission%20of%20nerve%20impulse ; - :transmission%20of%20nerve%20impulse . - -### http://www.co-ode.org/ontologies/ont.owl#transmission%20of%20nerve%20impulse - rdf:type owl:NamedIndividual , - ; - :excitatory%20postsynaptic%20potential . - -### http://www.co-ode.org/ontologies/ont.owl#excitatory%20postsynaptic%20potential - rdf:type owl:NamedIndividual , - ; - :muscle%20contraction . - -### http://www.co-ode.org/ontologies/ont.owl#muscle%20contraction - rdf:type owl:NamedIndividual , - ; - :chitin%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#chitin - rdf:type owl:NamedIndividual , - ; - :chitin%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#chitin%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Ecdysone receptor agonism leading to incomplete ecdysis associated mortality"^^ . diff --git a/models/AOP_40.ttl b/models/AOP_40.ttl index 74bd6b9d..73cdde8a 100644 --- a/models/AOP_40.ttl +++ b/models/AOP_40.ttl @@ -1,138 +1,73 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Hippocampal Physiology, Altered"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_59739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005515 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032980 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002534 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001775 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002396 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000084 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0042110 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000813 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#electrophilic%20reagant - rdf:type owl:NamedIndividual , - ; - :protein%20binding ; - :protein%20binding ; - :protein%20binding ; - :protein%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20binding - rdf:type owl:NamedIndividual , - ; - :cell%20activation ; - :MHC%20protein%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#keratinocyte%20activation - rdf:type owl:NamedIndividual , - ; - :cell%20activation ; - :MHC%20protein%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#cytokine%20production%20involved%20in%20inflammatory%20response - rdf:type owl:NamedIndividual , - ; - :cell%20activation ; - :MHC%20protein%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#MHC%20protein%20complex%20assembly - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20activation - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#MHC%20protein%20complex%20assembly - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#T%20cell - rdf:type owl:NamedIndividual , - ; - :T%20cell%20activation ; - :T%20cell%20activation ; - :T%20cell%20activation ; - :T%20cell%20activation . - -### http://www.co-ode.org/ontologies/ont.owl#T%20cell%20activation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#memory%20T%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + , ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + a . + + a . + + , ; + a , . + + , ; + a , . + + "development"^^ ; + a ; + "Covalent Protein binding leading to Skin Sensitisation"^^ . diff --git a/models/AOP_405.ttl b/models/AOP_405.ttl index 8bdfb51e..5a13f255 100644 --- a/models/AOP_405.ttl +++ b/models/AOP_405.ttl @@ -1,110 +1,69 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "activation of CCAAT/enhancer-binding protein alpha"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000003626 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003990 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_15355 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001393 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001399 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000753 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0099536 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050890 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholinesterase - rdf:type owl:NamedIndividual , - ; - :acetylcholinesterase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholinesterase%20activity - rdf:type owl:NamedIndividual , - ; - :acetylcholine ; - :acetylcholine ; - :acetylcholine ; - :acetylcholine . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine - rdf:type owl:NamedIndividual , - ; - :ataxia ; - :ataxia ; - :hyperactivity ; - :hyperactivity ; - :paralysis ; - :paralysis . - -### http://www.co-ode.org/ontologies/ont.owl#ataxia - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#hyperactivity - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#paralysis - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , , ; + , , ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + a . + + a . + + a , . + + "review"^^ ; + a ; + "Organo-Phosphate Chemicals induced inhibition of AChE leading to impaired cognitive function"^^ . diff --git a/models/AOP_406.ttl b/models/AOP_406.ttl index fd34b887..2186ef93 100644 --- a/models/AOP_406.ttl +++ b/models/AOP_406.ttl @@ -1,217 +1,110 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "increased adipogenesis"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0031381 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039694 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039690 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072516 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019074 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019024 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019081 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0034599 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000302 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072559 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0044546 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#endocytosis%20involved%20in%20viral%20entry%20into%20host%20cell - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :viral%20RNA%20genome%20packaging ; - :mRNA%20transcription ; - :viral%20translation . - -### http://www.co-ode.org/ontologies/ont.owl#protease%20binding - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :viral%20RNA%20genome%20packaging ; - :mRNA%20transcription ; - :viral%20translation . - -### http://www.co-ode.org/ontologies/ont.owl#neuropilin%20binding - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :viral%20RNA%20genome%20packaging ; - :mRNA%20transcription ; - :viral%20translation . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20replication - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#positive%20stranded%20viral%20RNA%20replication - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20assembly%20compartment - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20packaging - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription . - -### http://www.co-ode.org/ontologies/ont.owl#mRNA%20transcription - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20translation - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress ; - :cellular%20response%20to%20oxidative%20stress . - -### http://www.co-ode.org/ontologies/ont.owl#cellular%20response%20to%20oxidative%20stress - rdf:type owl:NamedIndividual , - ; - :NLRP3%20inflammasome%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species ; - :response%20to%20reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#response%20to%20reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - ; - :NLRP3%20inflammasome%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#NLRP3%20inflammasome%20complex - rdf:type owl:NamedIndividual , - ; - :NLRP3%20inflammasome%20complex%20assembly ; - :NLRP3%20inflammasome%20complex%20assembly ; - :NLRP3%20inflammasome%20complex%20assembly ; - :NLRP3%20inflammasome%20complex%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#NLRP3%20inflammasome%20complex%20assembly - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , , , , ; + a , . + + , ; + a , . + + , , , , ; + a , . + + , ; + a , . + + , , , , ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + , ; + a , . + + , ; + a , . + + , ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + ; + a , . + + "development"^^ ; + a ; + "SARS-CoV-2 infection leading to hyperinflammation"^^ . diff --git a/models/AOP_407.ttl b/models/AOP_407.ttl index e88aabcc..3d4c1320 100644 --- a/models/AOP_407.ttl +++ b/models/AOP_407.ttl @@ -1,81 +1,46 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "decreased dopamine"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0031381 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0039694 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0039690 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0072516 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019074 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019024 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019081 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0034599 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0000302 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0072559 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0044546 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "SARS-CoV-2 infection leading to pyroptosis"^^ . diff --git a/models/AOP_409.ttl b/models/AOP_409.ttl index c32e97ad..e6ff5107 100644 --- a/models/AOP_409.ttl +++ b/models/AOP_409.ttl @@ -1,80 +1,50 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "decreased DNA methylation of tyrosine hydroxylase"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CL_0000235 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006909 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D008654 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#macrophage - rdf:type owl:NamedIndividual , - ; - :phagocytosis ; - :phagocytosis ; - :phagocytosis ; - :phagocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#phagocytosis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :mesothelioma ; - :mesothelioma ; - :mesothelioma ; - :mesothelioma . - -### http://www.co-ode.org/ontologies/ont.owl#mesothelioma - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a , . + + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + "development"^^ ; + a ; + "Frustrated phagocytosis leads to malignant mesothelioma"^^ . diff --git a/models/AOP_41.ttl b/models/AOP_41.ttl index e6fb77bf..48fa23a4 100644 --- a/models/AOP_41.ttl +++ b/models/AOP_41.ttl @@ -1,164 +1,101 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Hippocampal gene expression, Altered "^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://id.nlm.nih.gov/mesh/D008107 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019725 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/FMA_63179 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0002196 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0002538 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D001650 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :cellular%20homeostasis ; - :apoptotic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#cellular%20homeostasis - rdf:type owl:NamedIndividual , - ; - :Liver%20Diseases ; - :Liver%20Diseases ; - :Liver%20Diseases ; - :Liver%20Diseases . - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - ; - :Liver%20Diseases ; - :Liver%20Diseases ; - :Liver%20Diseases ; - :Liver%20Diseases . - -### http://www.co-ode.org/ontologies/ont.owl#Liver%20Diseases - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :hyperplasia ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#Liver%20cell - rdf:type owl:NamedIndividual , - ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation ; - :cell%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma ; - :Bile%20Duct%20Neoplasms ; - :Bile%20Duct%20Neoplasms ; - :Bile%20Duct%20Neoplasms ; - :Bile%20Duct%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#hepatic%20oval%20stem%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma ; - :Bile%20Duct%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#intrahepatic%20bile%20duct%20epithelial%20cell - rdf:type owl:NamedIndividual , - ; - :hyperplasia . - -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma ; - :Bile%20Duct%20Neoplasms . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#Bile%20Duct%20Neoplasms - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Sustained AhR Activation leading to Rodent Liver Tumours"^^ . diff --git a/models/AOP_410.ttl b/models/AOP_410.ttl index a942f9b9..bb0878dd 100644 --- a/models/AOP_410.ttl +++ b/models/AOP_410.ttl @@ -1,57 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "decreased methylation of dopamine transporter promoter"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0030916 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007605 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#otic%20vesicle%20formation - rdf:type owl:NamedIndividual , - ; - :sensory%20perception%20of%20sound . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#sensory%20perception%20of%20sound - rdf:type owl:NamedIndividual , - ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "GSK3beta inactivation leading to increased mortality via defects in developing inner ear"^^ . diff --git a/models/AOP_411.ttl b/models/AOP_411.ttl index 7cde31f6..51591d98 100644 --- a/models/AOP_411.ttl +++ b/models/AOP_411.ttl @@ -1,66 +1,34 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "chronic high fat diet"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0031514 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0012262 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0001947 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0002327 - rdf:type owl:Class . + a , . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#motile%20cilium - rdf:type owl:NamedIndividual , - ; - :Abnormal%20ciliary%20motility ; - :Abnormal%20ciliary%20motility . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#Abnormal%20ciliary%20motility - rdf:type owl:NamedIndividual , - ; - :mucociliary%20clearance%20trait ; - :mucociliary%20clearance%20trait . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#mucociliary%20clearance%20trait - rdf:type owl:NamedIndividual , - ; - :respiratory%20function%20trait ; - :respiratory%20function%20trait . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20function%20trait - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Oxidative stress Leading to Decreased Lung Function "^^ . diff --git a/models/AOP_412.ttl b/models/AOP_412.ttl index fc8eba56..8d12687a 100644 --- a/models/AOP_412.ttl +++ b/models/AOP_412.ttl @@ -1,51 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, Inhibition of Dopamine-beta-hydroxylase"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/FMA_84050 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0050663 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#Cytokine - rdf:type owl:NamedIndividual , - ; - :cytokine%20secretion ; - :cytokine%20secretion ; - :cytokine%20secretion ; - :cytokine%20secretion . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#cytokine%20secretion - rdf:type owl:NamedIndividual , - . + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Endothelial cell dysfunction leading to thromboinflammation"^^ . diff --git a/models/AOP_413.ttl b/models/AOP_413.ttl index 88f99e7b..bdf6b093 100644 --- a/models/AOP_413.ttl +++ b/models/AOP_413.ttl @@ -1,84 +1,56 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased, Decreased fecundity "^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_16856 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0016209 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003606 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#glutathione - rdf:type owl:NamedIndividual , - ; - :antioxidant%20activity ; - :antioxidant%20activity ; - :antioxidant%20activity ; - :antioxidant%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#antioxidant%20activity - rdf:type owl:NamedIndividual , - ; - :reactive%20oxygen%20species ; - :reactive%20oxygen%20species ; - :reactive%20oxygen%20species ; - :reactive%20oxygen%20species . - -### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#kidney%20failure - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + "development"^^ ; + a ; + "Oxidation and antagonism of reduced glutathione leading to mortality via acute renal failure"^^ . diff --git a/models/AOP_414.ttl b/models/AOP_414.ttl index 232e1d39..5ab78ecf 100644 --- a/models/AOP_414.ttl +++ b/models/AOP_414.ttl @@ -1,39 +1,18 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, Synthesis of NE"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to lung fibrosis through TGF-Ī² dependent fibrosis toxicity pathway"^^ . diff --git a/models/AOP_415.ttl b/models/AOP_415.ttl index 26222d07..ddde8636 100644 --- a/models/AOP_415.ttl +++ b/models/AOP_415.ttl @@ -1,39 +1,18 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, GnRH cfos activity"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to lung fibrosis through IL-6 toxicity pathway"^^ . diff --git a/models/AOP_416.ttl b/models/AOP_416.ttl index effaa24f..021f77f7 100644 --- a/models/AOP_416.ttl +++ b/models/AOP_416.ttl @@ -1,42 +1,20 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, GnRH pulsatility/release"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to lung cancer through IL-6 toxicity pathway"^^ . diff --git a/models/AOP_417.ttl b/models/AOP_417.ttl index d84cd500..5de6acb4 100644 --- a/models/AOP_417.ttl +++ b/models/AOP_417.ttl @@ -1,39 +1,18 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, LH Surge"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to lung cancer through AHR-ARNT toxicity pathway"^^ . diff --git a/models/AOP_418.ttl b/models/AOP_418.ttl index 2488465c..7244098c 100644 --- a/models/AOP_418.ttl +++ b/models/AOP_418.ttl @@ -1,45 +1,22 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Delayed, Ovulation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_26523 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0002327 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to impaired lung function through AHR-ARNT toxicity pathway"^^ . diff --git a/models/AOP_419.ttl b/models/AOP_419.ttl index f5ea95c8..febdf342 100644 --- a/models/AOP_419.ttl +++ b/models/AOP_419.ttl @@ -1,45 +1,22 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, Cortical granule release/distribution upon fertilization"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0002327 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to impaired lung function through P53 toxicity pathway"^^ . diff --git a/models/AOP_42.ttl b/models/AOP_42.ttl index 3bde9f50..9cb1f033 100644 --- a/models/AOP_42.ttl +++ b/models/AOP_42.ttl @@ -1,177 +1,109 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Clearance of thyroxine from serum"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000016584 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004447 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010817 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050890 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002421 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007420 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0045202 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007268 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase - rdf:type owl:NamedIndividual , - ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity ; - :iodide%20peroxidase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20hormone%20levels - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - ; - :brain%20development . - -### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation - rdf:type owl:NamedIndividual , - ; - :brain%20development ; - :brain%20development ; - :brain%20development ; - :brain%20development . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20development - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#synapse - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission - rdf:type owl:NamedIndividual , - ; - :learning%20or%20memory ; - :cognition . - -### http://www.co-ode.org/ontologies/ont.owl#learning%20or%20memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cognition - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + , ; + a , . + + a , . + + , ; + , ; + , ; + , ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + "review"^^ ; + a ; + "Inhibition of Thyroperoxidase and Subsequent Adverse Neurodevelopmental Outcomes in Mammals"^^ . diff --git a/models/AOP_420.ttl b/models/AOP_420.ttl index 802a3374..5269af31 100644 --- a/models/AOP_420.ttl +++ b/models/AOP_420.ttl @@ -1,42 +1,20 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Altered, Formation of cortical envelope"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Aryl hydrocarbon receptor activation leading to lung cancer through sustained NRF2 toxicity pathway"^^ . diff --git a/models/AOP_422.ttl b/models/AOP_422.ttl index e7065efa..348c30c6 100644 --- a/models/AOP_422.ttl +++ b/models/AOP_422.ttl @@ -1,138 +1,70 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Altered, Chromosome number (polyploid) zygote"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0031381 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039694 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039690 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0072516 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019074 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019024 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019081 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#endocytosis%20involved%20in%20viral%20entry%20into%20host%20cell - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#protease%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#neuropilin%20binding - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20replication - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#positive%20stranded%20viral%20RNA%20replication - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20assembly%20compartment - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20packaging - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription . + a . -### http://www.co-ode.org/ontologies/ont.owl#mRNA%20transcription - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation . + a . -### http://www.co-ode.org/ontologies/ont.owl#viral%20translation - rdf:type owl:NamedIndividual , - . + a . + a . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a , . + + a , . + + a , . + + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "Binding of SARS-CoV-2 to ACE2 in enterocytes leads to intestinal barrier disruption"^^ . diff --git a/models/AOP_424.ttl b/models/AOP_424.ttl index 8c512090..b96a0d59 100644 --- a/models/AOP_424.ttl +++ b/models/AOP_424.ttl @@ -1,90 +1,56 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decreased testosterone by the fetal Leydig cells, Hypermethylation in the fetal testis"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005254 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0035963 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_0001947 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0031514 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/HP_0012262 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_0002327 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#chloride%20channel%20activity - rdf:type owl:NamedIndividual , - ; - :epithelial%20lining%20fluid ; - :epithelial%20lining%20fluid ; - :epithelial%20lining%20fluid ; - :epithelial%20lining%20fluid . - -### http://www.co-ode.org/ontologies/ont.owl#epithelial%20lining%20fluid - rdf:type owl:NamedIndividual , - ; - :Abnormal%20ciliary%20motility ; - :Abnormal%20ciliary%20motility . - -### http://www.co-ode.org/ontologies/ont.owl#motile%20cilium - rdf:type owl:NamedIndividual , - ; - :Abnormal%20ciliary%20motility ; - :Abnormal%20ciliary%20motility . - -### http://www.co-ode.org/ontologies/ont.owl#Abnormal%20ciliary%20motility - rdf:type owl:NamedIndividual , - ; - :mucociliary%20clearance%20trait ; - :mucociliary%20clearance%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#mucociliary%20clearance%20trait - rdf:type owl:NamedIndividual , - ; - :respiratory%20function%20trait ; - :respiratory%20function%20trait . - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20function%20trait - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + ; + ; + a , . + + "development"^^ ; + a ; + "Oxidative stress Leading to Decreased Lung Function via CFTR dysfunction"^^ . diff --git a/models/AOP_425.ttl b/models/AOP_425.ttl index b59ae7cb..d19240c8 100644 --- a/models/AOP_425.ttl +++ b/models/AOP_425.ttl @@ -1,83 +1,44 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased testosterone by the fetal Leydig cells, Increased COUP-TFII in fetal Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000007628 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0031514 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0012262 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0001947 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0002327 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#forkhead%20box%20protein%20J1 - rdf:type owl:NamedIndividual , - ; - :motile%20cilium ; - :motile%20cilium . + a . -### http://www.co-ode.org/ontologies/ont.owl#motile%20cilium - rdf:type owl:NamedIndividual , - ; - :Abnormal%20ciliary%20motility ; - :Abnormal%20ciliary%20motility . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#motile%20cilium - rdf:type owl:NamedIndividual , - ; - :Abnormal%20ciliary%20motility ; - :Abnormal%20ciliary%20motility . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#Abnormal%20ciliary%20motility - rdf:type owl:NamedIndividual , - ; - :mucociliary%20clearance%20trait ; - :mucociliary%20clearance%20trait . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#mucociliary%20clearance%20trait - rdf:type owl:NamedIndividual , - ; - :respiratory%20function%20trait ; - :respiratory%20function%20trait . + a . -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20function%20trait - rdf:type owl:NamedIndividual , - . + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Oxidative Stress Leading to Decreased Lung Function via Decreased FOXJ1"^^ . diff --git a/models/AOP_426.ttl b/models/AOP_426.ttl index 80b75497..f9b55e27 100644 --- a/models/AOP_426.ttl +++ b/models/AOP_426.ttl @@ -1,38 +1,12 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased testosterone by the fetal Leydig cells, Dysgensis of fetal Leydig cells"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# + a . + "review"^^ ; + a ; + "SARS-CoV-2 spike protein binding to ACE2 receptors expressed on pericytes leads to endothelial cell dysfunction, microvascular injury and myocardial infarction. "^^ . diff --git a/models/AOP_428.ttl b/models/AOP_428.ttl index 7c4663f5..fd3ffbb2 100644 --- a/models/AOP_428.ttl +++ b/models/AOP_428.ttl @@ -1,85 +1,34 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, Nicotinic acetylcholine receptor"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003622 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004180 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0034394 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#angiotensin-converting%20enzyme%202 - rdf:type owl:NamedIndividual , - ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription . + a . -### http://www.co-ode.org/ontologies/ont.owl#mRNA%20transcription - rdf:type owl:NamedIndividual , - . + , , ; + , , ; + , , ; + , , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#angiotensin-converting%20enzyme%202 - rdf:type owl:NamedIndividual , - ; - :carboxypeptidase%20activity ; - :carboxypeptidase%20activity ; - :carboxypeptidase%20activity ; - :carboxypeptidase%20activity . + a , . -### http://www.co-ode.org/ontologies/ont.owl#carboxypeptidase%20activity - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#angiotensin-converting%20enzyme%202 - rdf:type owl:NamedIndividual , - ; - :protein%20localization%20to%20cell%20surface ; - :protein%20localization%20to%20cell%20surface ; - :protein%20localization%20to%20cell%20surface ; - :protein%20localization%20to%20cell%20surface . - -### http://www.co-ode.org/ontologies/ont.owl#protein%20localization%20to%20cell%20surface - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#angiotensin-converting%20enzyme%202 - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Binding of S-protein to ACE2 in enterocytes induces ACE2 dysregulation leading to gut dysbiosis "^^ . diff --git a/models/AOP_429.ttl b/models/AOP_429.ttl index 436c1899..4b3343c8 100644 --- a/models/AOP_429.ttl +++ b/models/AOP_429.ttl @@ -1,77 +1,36 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Mitochondrial dysfunction 1"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0099536 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000129 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001847 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000127 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling ; - :synaptic%20signaling . + a . -### http://www.co-ode.org/ontologies/ont.owl#astrocyte - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . + a , . -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "A cholesterol/glucose dysmetabolism initiated Tau-driven AOP toward memory loss (AO) in sporadic Alzheimers Disease with plausible MIEs plug-ins for environmental neurotoxicants"^^ . diff --git a/models/AOP_43.ttl b/models/AOP_43.ttl index fa15acce..192c5586 100644 --- a/models/AOP_43.ttl +++ b/models/AOP_43.ttl @@ -1,96 +1,54 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Ionotropic GABA receptor chloride channel conductance"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000002112 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0043184 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000007563 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001525 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0003158 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0000178 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0008015 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0035753 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/GO_0009653 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20receptor%202 - rdf:type owl:NamedIndividual , - ; - :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; - :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; - :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; - :vascular%20endothelial%20growth%20factor%20receptor%202%20binding . + a . -### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20receptor%202%20binding - rdf:type owl:NamedIndividual , - ; - :angiogenesis . + a . -### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20receptor%201 - rdf:type owl:NamedIndividual , - ; - :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; - :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; - :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; - :vascular%20endothelial%20growth%20factor%20receptor%202%20binding . + a . -### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20receptor%202%20binding - rdf:type owl:NamedIndividual , - ; - :angiogenesis . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#angiogenesis - rdf:type owl:NamedIndividual , - ; - :endothelium%20development . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#endothelium%20development - rdf:type owl:NamedIndividual , - . + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Disruption of VEGFR Signaling Leading to Developmental Defects"^^ . diff --git a/models/AOP_430.ttl b/models/AOP_430.ttl index d5885c11..1248e138 100644 --- a/models/AOP_430.ttl +++ b/models/AOP_430.ttl @@ -1,203 +1,110 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Impairment, Learning and memory"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0075509 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0038191 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_62488 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060337 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0038197 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0071357 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0031381 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039694 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0039690 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072516 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019074 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019024 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019081 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019076 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#endocytosis%20involved%20in%20viral%20entry%20into%20host%20cell - rdf:type owl:NamedIndividual , - ; - :type%20I%20interferon%20signaling%20pathway ; - :cellular%20response%20to%20type%20I%20interferon . - -### http://www.co-ode.org/ontologies/ont.owl#protease%20binding - rdf:type owl:NamedIndividual , - ; - :type%20I%20interferon%20signaling%20pathway ; - :cellular%20response%20to%20type%20I%20interferon . - -### http://www.co-ode.org/ontologies/ont.owl#neuropilin%20binding - rdf:type owl:NamedIndividual , - ; - :type%20I%20interferon%20signaling%20pathway ; - :cellular%20response%20to%20type%20I%20interferon . - -### http://www.co-ode.org/ontologies/ont.owl#signalling%20molecule - rdf:type owl:NamedIndividual , - ; - :type%20I%20interferon%20signaling%20pathway ; - :type%20I%20interferon%20signaling%20pathway ; - :type%20I%20interferon%20signaling%20pathway ; - :type%20I%20interferon%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#type%20I%20interferon%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :viral%20RNA%20genome%20packaging ; - :mRNA%20transcription ; - :viral%20translation . - -### http://www.co-ode.org/ontologies/ont.owl#type%20I%20interferon%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :cellular%20response%20to%20type%20I%20interferon ; - :cellular%20response%20to%20type%20I%20interferon ; - :cellular%20response%20to%20type%20I%20interferon ; - :cellular%20response%20to%20type%20I%20interferon . - -### http://www.co-ode.org/ontologies/ont.owl#cellular%20response%20to%20type%20I%20interferon - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :viral%20RNA%20genome%20packaging ; - :mRNA%20transcription ; - :viral%20translation . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication ; - :viral%20RNA%20genome%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20replication - rdf:type owl:NamedIndividual , - ; - :viral%20release%20from%20host%20cell . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA-directed%20RNA%20polymerase%20complex - rdf:type owl:NamedIndividual , - ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication ; - :positive%20stranded%20viral%20RNA%20replication . - -### http://www.co-ode.org/ontologies/ont.owl#positive%20stranded%20viral%20RNA%20replication - rdf:type owl:NamedIndividual , - ; - :viral%20release%20from%20host%20cell . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20assembly%20compartment - rdf:type owl:NamedIndividual , - ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging ; - :viral%20RNA%20genome%20packaging . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20RNA%20genome%20packaging - rdf:type owl:NamedIndividual , - ; - :viral%20release%20from%20host%20cell . - -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription ; - :mRNA%20transcription . - -### http://www.co-ode.org/ontologies/ont.owl#mRNA%20transcription - rdf:type owl:NamedIndividual , - ; - :viral%20release%20from%20host%20cell . - -### http://www.co-ode.org/ontologies/ont.owl#ssRNA%20viral%20genome - rdf:type owl:NamedIndividual , - ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation ; - :viral%20translation . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20translation - rdf:type owl:NamedIndividual , - ; - :viral%20release%20from%20host%20cell . - -### http://www.co-ode.org/ontologies/ont.owl#viral%20release%20from%20host%20cell - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + ; + a , . + + , ; + a , . + + ; + a , . + + , ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + , , , , ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , , , , ; + a , . + + a , . + + "development"^^ ; + a ; + "Binding of SARS-CoV-2 to ACE2 leads to viral infection proliferation"^^ . diff --git a/models/AOP_46.ttl b/models/AOP_46.ttl index a82d49b0..2a55dda9 100644 --- a/models/AOP_46.ttl +++ b/models/AOP_46.ttl @@ -1,119 +1,73 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Binding at picrotoxin site, iGABAR chloride channel"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/FMA_67194 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006305 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D006528 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000003035 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009154 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008152 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000182 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0072574 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte - rdf:type owl:NamedIndividual , - ; - :hepatocyte%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte%20proliferation - rdf:type owl:NamedIndividual , - ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma ; - :hepatocellular%20carcinoma . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocellular%20carcinoma - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cellular%20tumor%20antigen%20p53 - rdf:type owl:NamedIndividual , - ; - :mutation . - -### http://www.co-ode.org/ontologies/ont.owl#mutation - rdf:type owl:NamedIndividual , - ; - :hepatocyte%20proliferation . - -### http://www.co-ode.org/ontologies/ont.owl#Nuclear%20deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20alkylation ; - :DNA%20alkylation ; - :DNA%20alkylation ; - :DNA%20alkylation . - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20alkylation - rdf:type owl:NamedIndividual , - ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#Nuclear%20deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - ; - :mutation . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + "review"^^ ; + a ; + "AFB1: Mutagenic Mode-of-Action leading to Hepatocellular Carcinoma (HCC)"^^ . diff --git a/models/AOP_48.ttl b/models/AOP_48.ttl index 5757a7ce..3264f777 100644 --- a/models/AOP_48.ttl +++ b/models/AOP_48.ttl @@ -1,219 +1,119 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Generation, Amplified excitatory postsynaptic potential (EPSP)"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008219 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002229 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0017146 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004972 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006816 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0099536 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008328 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004970 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000129 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001847 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000127 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#neurodegeneration - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#neurodegeneration - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :neurodegeneration ; - :neurodegeneration . - -### http://www.co-ode.org/ontologies/ont.owl#astrocyte - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :neurodegeneration ; - :neurodegeneration . - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex - rdf:type owl:NamedIndividual , - ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity ; - :NMDA%20glutamate%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :calcium%20ion%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :cell%20death ; - :cell%20death ; - :cell%20death ; - :cell%20death . - -### http://www.co-ode.org/ontologies/ont.owl#cell%20death - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :neurodegeneration ; - :neurodegeneration . - -### http://www.co-ode.org/ontologies/ont.owl#astrocyte - rdf:type owl:NamedIndividual , - ; - :brain%20inflammation ; - :brain%20inflammation . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation - rdf:type owl:NamedIndividual , - ; - :neurodegeneration ; - :neurodegeneration . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + a , . + + a . + + , ; + a , . + + a . + + a . + + "review"^^ ; + a ; + "Binding of agonists to ionotropic glutamate receptors in adult brain causes excitotoxicity that mediates neuronal cell death, contributing to learning and memory impairment."^^ . diff --git a/models/AOP_51.ttl b/models/AOP_51.ttl index 7e55ce91..bbca30d1 100644 --- a/models/AOP_51.ttl +++ b/models/AOP_51.ttl @@ -1,98 +1,62 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Neurodegeneration"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042446 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D006965 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0008283 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0061370 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_16113 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0006839 - rdf:type owl:Class . + ; + ; + ; + ; + a , . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation - rdf:type owl:NamedIndividual , - ; - :hyperplasia . + a . -### http://www.co-ode.org/ontologies/ont.owl#hyperplasia - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#testosterone%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :testosterone ; - :testosterone ; - :testosterone ; - :testosterone . + a . + a . + a , . -################################################################# -# Object Statements -################################################################# + a . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + "review"^^ ; + a ; + "PPARĪ± activation leading to impaired fertility in adult male rodents "^^ . diff --git a/models/AOP_52.ttl b/models/AOP_52.ttl index a77ff9d8..6faf2a76 100644 --- a/models/AOP_52.ttl +++ b/models/AOP_52.ttl @@ -1,42 +1,20 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, Calcium influx"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030284 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D012744 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "ER agonism leading to skewed sex ratios due to altered sexual differentiation in males"^^ . diff --git a/models/AOP_53.ttl b/models/AOP_53.ttl index 8c90aba0..9e928b34 100644 --- a/models/AOP_53.ttl +++ b/models/AOP_53.ttl @@ -1,54 +1,28 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Binding of antagonist, NMDA receptors"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030284 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D014819 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0005777 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001914 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0000112 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "ER agonism leading to reduced survival due to renal failure"^^ . diff --git a/models/AOP_54.ttl b/models/AOP_54.ttl index 1f82a7a0..f6da8cd5 100644 --- a/models/AOP_54.ttl +++ b/models/AOP_54.ttl @@ -1,208 +1,127 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduced levels of BDNF"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16382 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0015705 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010817 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000004716 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046903 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0045202 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007416 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002882 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000015171 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008507 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0099536 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#sodium/iodide%20cotransporter - rdf:type owl:NamedIndividual , - ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#sodium%3Aiodide%20symporter%20activity - rdf:type owl:NamedIndividual , - ; - :iodide%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#iodide - rdf:type owl:NamedIndividual , - ; - :iodide%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#iodide%20transport - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20hormone%20levels - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :secretion . - -### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :abnormal%20neuron%20morphology . - -### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor - rdf:type owl:NamedIndividual , - ; - :secretion ; - :secretion ; - :secretion ; - :secretion . - -### http://www.co-ode.org/ontologies/ont.owl#secretion - rdf:type owl:NamedIndividual , - ; - :abnormal%20neuron%20morphology . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20neuron%20morphology - rdf:type owl:NamedIndividual , - ; - :synapse%20assembly ; - :synapse%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#synapse - rdf:type owl:NamedIndividual , - ; - :synapse%20assembly . - -### http://www.co-ode.org/ontologies/ont.owl#synapse%20assembly - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + , ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a , . + + a , . + + a . + + , ; + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + a , . + + "review"^^ ; + a ; + "Inhibition of Na+/I- symporter (NIS) leads to learning and memory impairment "^^ . diff --git a/models/AOP_57.ttl b/models/AOP_57.ttl index c5327775..4df42035 100644 --- a/models/AOP_57.ttl +++ b/models/AOP_57.ttl @@ -1,212 +1,127 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Impairment, Learning and memory"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003858 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004874 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_39027 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0046903 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_35366 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006635 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000012416 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17855 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001905 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015908 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000009744 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39026 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006898 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000006101 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000014497 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#very-low-density%20lipoprotein - rdf:type owl:NamedIndividual , - ; - :secretion ; - :secretion ; - :secretion ; - :secretion . - -### http://www.co-ode.org/ontologies/ont.owl#secretion - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#platelet%20glycoprotein%204 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#phosphoenolpyruvate%20carboxykinase%2C%20cytosolic%20%5BGTP%5D - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20transport - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#low-density%20lipoprotein%20receptor - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#low-density%20lipoprotein - rdf:type owl:NamedIndividual , - ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis ; - :receptor-mediated%20endocytosis . - -### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cytochrome%20P450%201A1 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#acyl-CoA%20desaturase - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :triglyceride ; - :triglyceride ; - :triglyceride ; - :triglyceride . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + , ; + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "AhR activation leading to hepatic steatosis"^^ . diff --git a/models/AOP_58.ttl b/models/AOP_58.ttl index edb740a4..b2b6a7ed 100644 --- a/models/AOP_58.ttl +++ b/models/AOP_58.ttl @@ -1,412 +1,175 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Binding of antagonist, NMDA receptors"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000011398 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000015611 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0032933 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000010460 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_35366 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006633 - rdf:type owl:Class . + , , , ; + a , . -### http://purl.obolibrary.org/obo/CHEBI_17855 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019432 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0009058 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000001905 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . + , , , ; + a , . -### http://purl.obolibrary.org/obo/PR_000014497 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007348 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000011394 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000011395 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013058 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006635 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000003596 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003989 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015908 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#nuclear%20receptor%20subfamily%201%20group%20I%20member%203 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#oxysterols%20receptor%20LXR-beta - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :acetyl-CoA%20carboxylase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#oxysterols%20receptor%20LXR-alpha - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :acetyl-CoA%20carboxylase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20gamma - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#sterol%20regulatory%20element-binding%20protein%201 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#sterol%20regulatory%20element-binding%20protein%201 - rdf:type owl:NamedIndividual , - ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#SREBP%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#carbohydrate-responsive%20element-binding%20protein - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#sterol%20regulatory%20element-binding%20protein%201 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#sterol%20regulatory%20element-binding%20protein%201 - rdf:type owl:NamedIndividual , - ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#SREBP%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#acyl-CoA%20desaturase - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :triglyceride%20biosynthetic%20process ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#platelet%20glycoprotein%204 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20synthase - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#acyl-CoA%20desaturase - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :triglyceride%20biosynthetic%20process ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :triglyceride%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20beta-oxidation - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :triglyceride%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#acetyl-CoA%20carboxylase%201 - rdf:type owl:NamedIndividual , - ; - :acetyl-CoA%20carboxylase%20activity ; - :acetyl-CoA%20carboxylase%20activity ; - :acetyl-CoA%20carboxylase%20activity ; - :acetyl-CoA%20carboxylase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetyl-CoA%20carboxylase%20activity - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20transport - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20transport - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + , ; + , ; + , , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + a . + + ; + a , . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + a , . + + "development"^^ ; + a ; + "NR1I3 (CAR) suppression leading to hepatic steatosis"^^ . diff --git a/models/AOP_59.ttl b/models/AOP_59.ttl index 3e956008..4e0d5875 100644 --- a/models/AOP_59.ttl +++ b/models/AOP_59.ttl @@ -1,39 +1,18 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, Calcium influx"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000008654 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "HNF4alpha suppression leading to hepatic steatosis"^^ . diff --git a/models/AOP_6.ttl b/models/AOP_6.ttl index c620ebe3..9512a274 100644 --- a/models/AOP_6.ttl +++ b/models/AOP_6.ttl @@ -1,116 +1,65 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "N/A, Mitochondrial dysfunction 1"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035624 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D007662 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0002118 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_73693 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001263 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D009124 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/GO_0030163 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0048019 - rdf:type owl:Class . + ; + ; + ; + ; + a , . -### http://purl.obolibrary.org/obo/PR_000011048 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0003714 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011047 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006635 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20alpha - rdf:type owl:NamedIndividual , - ; - :receptor%20transactivation ; - :receptor%20transactivation ; - :receptor%20transactivation ; - :receptor%20transactivation . + a . -### http://www.co-ode.org/ontologies/ont.owl#receptor%20transactivation - rdf:type owl:NamedIndividual , - ; - :ketosis . + a . -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20beta-oxidation - rdf:type owl:NamedIndividual , - ; - :ketosis . + a . -### http://www.co-ode.org/ontologies/ont.owl#ketosis - rdf:type owl:NamedIndividual , - ; - :abnormal%20lipid%20homeostasis ; - :ketone%20body . + a . -### http://www.co-ode.org/ontologies/ont.owl#ketosis - rdf:type owl:NamedIndividual , - ; - :abnormal%20lipid%20homeostasis ; - :ketone%20body . + a , . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20lipid%20homeostasis - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#ketone%20body - rdf:type owl:NamedIndividual , - . + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#weight%20loss - rdf:type owl:NamedIndividual , - . + ; + a , . + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Antagonist binding to PPARĪ± leading to body-weight loss"^^ . diff --git a/models/AOP_60.ttl b/models/AOP_60.ttl index b74f9e04..7286e961 100644 --- a/models/AOP_60.ttl +++ b/models/AOP_60.ttl @@ -1,242 +1,117 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Inhibition, NMDARs"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000011397 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000007603 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_35366 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006635 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000005835 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000008638 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000014497 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001905 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015908 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D007662 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17855 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019432 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009058 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#platelet%20glycoprotein%204 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20transport - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#ketosis - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#hepatocyte%20nuclear%20factor%203-beta - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20beta-oxidation - rdf:type owl:NamedIndividual , - ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid ; - :fatty%20acid . - -### http://www.co-ode.org/ontologies/ont.owl#platelet%20glycoprotein%204 - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20transport . - -### http://www.co-ode.org/ontologies/ont.owl#acyl-CoA%20desaturase - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :triglyceride%20biosynthetic%20process ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#hydroxymethylglutaryl-CoA%20synthase%2C%20mitochondrial - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :ketosis . - -### http://www.co-ode.org/ontologies/ont.owl#carnitine%20O-palmitoyltransferase%201%2C%20liver%20isoform - rdf:type owl:NamedIndividual , - ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression ; - :gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#gene%20expression - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20beta-oxidation . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :triglyceride%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :triglyceride%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#triglyceride - rdf:type owl:NamedIndividual , - ; - :biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#biosynthetic%20process - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , , , , ; + a , . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + a . + + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a , . + + a . + + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "NR1I2 (Pregnane X Receptor, PXR) activation leading to hepatic steatosis"^^ . diff --git a/models/AOP_61.ttl b/models/AOP_61.ttl index dfd33e21..fe0725f0 100644 --- a/models/AOP_61.ttl +++ b/models/AOP_61.ttl @@ -1,189 +1,108 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Impairment, Learning and memory"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000011170 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011396 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011391 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000013056 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000008778 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_35366 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006635 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000011395 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000015611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032933 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000003392 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004145 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010467 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17855 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009058 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006633 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#nuclear%20factor%20erythroid%202-related%20factor%202 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#bile%20acid%20receptor - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#nuclear%20receptor%20subfamily%200%20group%20B%20member%202 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :SREBP%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20alpha - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#oxysterols%20receptor%20LXR-alpha - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation ; - :fatty%20acid%20beta-oxidation . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20beta-oxidation - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#sterol%20regulatory%20element-binding%20protein%201 - rdf:type owl:NamedIndividual , - ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway ; - :SREBP%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#SREBP%20signaling%20pathway - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid - rdf:type owl:NamedIndividual , - ; - :fatty%20acid%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + , , , ; + a , . + + a . + + a . + + a . + + ; + ; + , ; + ; + a , . + + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + "development"^^ ; + a ; + "NFE2L2/FXR activation leading to hepatic steatosis"^^ . diff --git a/models/AOP_62.ttl b/models/AOP_62.ttl index 756af94f..4241e964 100644 --- a/models/AOP_62.ttl +++ b/models/AOP_62.ttl @@ -1,48 +1,24 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduced levels of BDNF"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000003912 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006954 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000015611 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0032933 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "AKT2 activation leading to hepatic steatosis"^^ . diff --git a/models/AOP_63.ttl b/models/AOP_63.ttl index 6155d44a..c79a45ca 100644 --- a/models/AOP_63.ttl +++ b/models/AOP_63.ttl @@ -1,107 +1,119 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Aberrant, Dendritic morphology"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0022414 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0000003 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013427 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004666 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000013428 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030728 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_26333 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin - rdf:type owl:NamedIndividual , - ; - :ovulation ; - :ovulation ; - :ovulation ; - :ovulation . - -### http://www.co-ode.org/ontologies/ont.owl#ovulation - rdf:type owl:NamedIndividual , - ; - :reproductive%20process ; - :reproduction . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20process - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#reproduction - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#prostaglandin - rdf:type owl:NamedIndividual , - ; - :ovulation ; - :ovulation ; - :ovulation ; - :ovulation . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :population%20growth%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + "468.75"^^ ; + "75"^^ ; + a , ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . + + a . + + a . + + a . + + a . + + a . + + "862.5"^^ ; + "381.25"^^ ; + ; + a , ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . + + a . + + ; + "468.75"^^ ; + "381.25"^^ ; + a , ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . + + a . + + ; + "75"^^ ; + "381.25"^^ ; + a , ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . + + a . + + a . + + a . + + a . + + a . + + ; + "458.75"^^ ; + "698.5"^^ ; + ; + a , ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . + + ; + "468.75"^^ ; + "993.75"^^ ; + a , ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . + + "review"^^ ; + ; + a ; + "Cyclooxygenase inhibition leading to reproductive dysfunction"^^ ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + +_:t2053 ; + ; + ; + a ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . + +_:t2054 ; + ; + ; + a ; + "https://orcid.org/0000-0001-9356-3475"^^ ; + "2023-08-14"^^ . diff --git a/models/AOP_64.ttl b/models/AOP_64.ttl index d980e243..1a318b60 100644 --- a/models/AOP_64.ttl +++ b/models/AOP_64.ttl @@ -1,161 +1,90 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease of synaptogenesis"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000011406 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0004883 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0042446 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0061370 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/VT_0002673 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CL_0000019 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor - rdf:type owl:NamedIndividual , - ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity ; - :glucocorticoid%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#glucocorticoid%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :hormone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :hormone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#hormone%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :testosterone ; - :testosterone ; - :testosterone ; - :testosterone . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :testosterone%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :testosterone ; - :testosterone ; - :testosterone ; - :testosterone . - -### http://www.co-ode.org/ontologies/ont.owl#testosterone - rdf:type owl:NamedIndividual , - ; - :sperm%20quantity ; - :sperm%20quantity ; - :sperm ; - :sperm ; - :fertility ; - :fertility ; - :sperm ; - :sperm . - -### http://www.co-ode.org/ontologies/ont.owl#sperm%20quantity - rdf:type owl:NamedIndividual , - ; - :fertility ; - :fertility . - -### http://www.co-ode.org/ontologies/ont.owl#sperm - rdf:type owl:NamedIndividual , - ; - :fertility . - -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - ; - :fertility . - -### http://www.co-ode.org/ontologies/ont.owl#sperm - rdf:type owl:NamedIndividual , - ; - :fertility . - -### http://www.co-ode.org/ontologies/ont.owl#fertility - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + ; + , ; + , ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + ; + ; + a , . + + "review"^^ ; + a ; + "Glucocorticoid Receptor (GR) Mediated Adult Leydig Cell Dysfunction Leading to Decreased Male Fertility"^^ . diff --git a/models/AOP_65.ttl b/models/AOP_65.ttl index 4884b0fc..dda1de8f 100644 --- a/models/AOP_65.ttl +++ b/models/AOP_65.ttl @@ -1,138 +1,87 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease of neuronal network function"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000015171 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008507 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/CHEBI_60311 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006590 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010817 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0001016 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0048856 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0003633 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0050890 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#sodium/iodide%20cotransporter - rdf:type owl:NamedIndividual , - ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity ; - :sodium%3Aiodide%20symporter%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#sodium%3Aiodide%20symporter%20activity - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone - rdf:type owl:NamedIndividual , - ; - :thyroid%20hormone%20generation . - -### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20hormone%20levels - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20nervous%20system%20physiology - rdf:type owl:NamedIndividual , - ; - :learning%20or%20memory ; - :learning%20or%20memory ; - :cognition ; - :cognition . - -### http://www.co-ode.org/ontologies/ont.owl#learning%20or%20memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#cognition - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + , ; + a , . + + a , . + + ; + ; + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "AOP 65"^^ . diff --git a/models/AOP_66.ttl b/models/AOP_66.ttl index a5fc31f8..6392dc67 100644 --- a/models/AOP_66.ttl +++ b/models/AOP_66.ttl @@ -1,63 +1,34 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduced, Presynaptic release of glutamate"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000019 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_16827 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011406 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004883 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011405 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035624 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0013604 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0013603 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0008715 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Modulation of Adult Leydig Cell Function Subsequent Glucocorticoid Activation in the Fetal Testis"^^ . diff --git a/models/AOP_67.ttl b/models/AOP_67.ttl index e432e658..e1178a56 100644 --- a/models/AOP_67.ttl +++ b/models/AOP_67.ttl @@ -1,60 +1,32 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Cell injury/death"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000019 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000007204 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0030284 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011405 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035624 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0013603 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0008715 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0013604 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Modulation of Adult Leydig Cell Function Subsequent to Estradiaol Activation in the Fetal Testis"^^ . diff --git a/models/AOP_68.ttl b/models/AOP_68.ttl index b9155c0f..c8e790b9 100644 --- a/models/AOP_68.ttl +++ b/models/AOP_68.ttl @@ -1,57 +1,30 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Activation, Glucocorticoid Receptor"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000019 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D005326 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011405 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035624 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0013603 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0008715 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0013604 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Modulation of Adult Leydig Cell Function Subsequent to Alterations in the Fetal Testis Protome"^^ . diff --git a/models/AOP_69.ttl b/models/AOP_69.ttl index cb5da5e8..45a8ca8c 100644 --- a/models/AOP_69.ttl +++ b/models/AOP_69.ttl @@ -1,55 +1,26 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Inhibition, Nuclear factor kappa B (NF-kB)"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16113 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006695 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_6495 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042953 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0032367 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0061370 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000019 - rdf:type owl:Class . + a . + a . - -################################################################# -# Individuals -################################################################# - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Modulation of Adult Leydig Cell Function Subsequent to Decreased Cholesterol Synthesis or Transport in the Adult Leydig Cell"^^ . diff --git a/models/AOP_7.ttl b/models/AOP_7.ttl index 0ab00591..9eb9502c 100644 --- a/models/AOP_7.ttl +++ b/models/AOP_7.ttl @@ -1,92 +1,52 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Impaired, Proteostasis"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/CHEBI_16469 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006703 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0042698 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000006100 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0070330 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009299 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :ovulation%20cycle ; - :ovulation%20cycle ; - :ovulation%20cycle ; - :ovulation%20cycle . - -### http://www.co-ode.org/ontologies/ont.owl#ovulation%20cycle - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :ovulation%20cycle ; - :ovulation%20cycle ; - :ovulation%20cycle ; - :ovulation%20cycle . - -### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol - rdf:type owl:NamedIndividual , - ; - :estrogen%20biosynthetic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process - rdf:type owl:NamedIndividual , - ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol ; - :17beta-estradiol . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + , ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a , . + + "review"^^ ; + a ; + "Aromatase (Cyp19a1) reduction leading to impaired fertility in adult female"^^ . diff --git a/models/AOP_70.ttl b/models/AOP_70.ttl index cb5d68e5..6291be5e 100644 --- a/models/AOP_70.ttl +++ b/models/AOP_70.ttl @@ -1,57 +1,30 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Suppression, Inflammatory cytokines"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/VT_0002673 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000019 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006694 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0050810 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000178 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007010 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Modulation of Adult Leydig Cell Function Subsequent to Proteomic Alterations in the Adult Leydig Cell"^^ . diff --git a/models/AOP_71.ttl b/models/AOP_71.ttl index 3dac0381..8e8b6436 100644 --- a/models/AOP_71.ttl +++ b/models/AOP_71.ttl @@ -1,66 +1,36 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased, Lymphocytes"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_17347 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006915 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0002673 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000019 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_24261 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0006704 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001775 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011406 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004883 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0050810 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Modulation of Adult Leydig Cell Function Subsequent to Glucocorticoid Activation"^^ . diff --git a/models/AOP_72.ttl b/models/AOP_72.ttl index 084445d0..816ca214 100644 --- a/models/AOP_72.ttl +++ b/models/AOP_72.ttl @@ -1,77 +1,29 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Induction, IKB inhibitory protein"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000013058 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035357 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20gamma - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . + a . -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20gamma - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20gamma - rdf:type owl:NamedIndividual , - ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway ; - :peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway . - -### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator%20activated%20receptor%20signaling%20pathway - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Epigenetic modification of PPARG leading to adipogenesis"^^ . diff --git a/models/AOP_73.ttl b/models/AOP_73.ttl index d98b1797..1e80601a 100644 --- a/models/AOP_73.ttl +++ b/models/AOP_73.ttl @@ -1,89 +1,54 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Increased, Disease susceptibility"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000006294 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0004500 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001921 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_18357 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0042421 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_P01101 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D007987 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046879 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CHEBI_81568 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0033684 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001928 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0060473 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046903 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0060387 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035037 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0004023 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . + a . + a . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Xenobiotic Inhibition of Dopamine-beta-Hydroxylase and subsequent reduced fecundity"^^ . diff --git a/models/AOP_74.ttl b/models/AOP_74.ttl index 61878b0b..9a1a1c9d 100644 --- a/models/AOP_74.ttl +++ b/models/AOP_74.ttl @@ -1,57 +1,30 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Suppression, Immune system"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://id.nlm.nih.gov/mesh/D005298 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/CL_0000019 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0044026 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000011405 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0035624 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0013603 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/HP_0008715 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0013604 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Modulation of Adult Leydig Cell Function Subsequent to Hypermethylation in the Fetal Testis"^^ . diff --git a/models/AOP_77.ttl b/models/AOP_77.ttl index 6d0dda2a..98b64423 100644 --- a/models/AOP_77.ttl +++ b/models/AOP_77.ttl @@ -1,173 +1,101 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increase, Mutations"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005488 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004978 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005516 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding ; - :signaling ; - :signaling ; - :signaling ; - :signaling ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#calmodulin - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#calmodulin%20binding - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + , , ; + , , ; + , , ; + , , ; + a , . + + a . + + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony death/failure 1"^^ . diff --git a/models/AOP_78.ttl b/models/AOP_78.ttl index 6957471e..e264295f 100644 --- a/models/AOP_78.ttl +++ b/models/AOP_78.ttl @@ -1,129 +1,87 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Inadequate DNA repair"^^xsd:string . - "review"^^xsd:string . - -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0099536 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019098 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001386 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002164 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling ; - :synaptic%20signaling ; - :synaptic%20signaling ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20behavior - rdf:type owl:NamedIndividual , - ; - :larval%20development . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20maternal%20nurturing - rdf:type owl:NamedIndividual , - ; - :larval%20development ; - :larval%20development . - -### http://www.co-ode.org/ontologies/ont.owl#larval%20development - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + a , . + + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + a , . + + , ; + a , . + + "development"^^ ; + a ; + "Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1"^^ . diff --git a/models/AOP_79.ttl b/models/AOP_79.ttl index d4475862..ca26cf69 100644 --- a/models/AOP_79.ttl +++ b/models/AOP_79.ttl @@ -1,88 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increased Mortality"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000051 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :thermoregulation%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#thermoregulation%20behavior - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + "review"^^ ; + a ; + "Nicotinic acetylcholine receptor activation contributes to impaired hive thermoregulation and leads to colony loss/failure"^^ . diff --git a/models/AOP_8.ttl b/models/AOP_8.ttl index 18e2be4a..dc8ebd4c 100644 --- a/models/AOP_8.ttl +++ b/models/AOP_8.ttl @@ -1,222 +1,126 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Neuroinflammation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000011397 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000011398 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000032 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_30660 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010817 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005475 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000001325 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015020 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0003824 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/UBERON_0002421 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007420 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0045202 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007268 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0010468 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0008152 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#nuclear%20receptor%20subfamily%201%20group%20I%20member%202 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :glucuronosyltransferase%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#nuclear%20receptor%20subfamily%201%20group%20I%20member%203 - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :glucuronosyltransferase%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#beta-1%2C3-glucuronyltransferase - rdf:type owl:NamedIndividual , - ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity ; - :glucuronosyltransferase%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#glucuronosyltransferase%20activity - rdf:type owl:NamedIndividual , - ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#beta-1%2C3-glucuronyltransferase - rdf:type owl:NamedIndividual , - ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity ; - :catalytic%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity - rdf:type owl:NamedIndividual , - ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process ; - :metabolic%20process . - -### http://www.co-ode.org/ontologies/ont.owl#metabolic%20process - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :abnormal%20circulating%20thyroxine%20level ; - :abnormal%20circulating%20thyroxine%20level . - -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#thyroxine - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels ; - :regulation%20of%20hormone%20levels . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20hormone%20levels - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation - rdf:type owl:NamedIndividual , - ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression ; - :regulation%20of%20gene%20expression . - -### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression - rdf:type owl:NamedIndividual , - ; - :brain%20development . - -### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation - rdf:type owl:NamedIndividual , - ; - :brain%20development ; - :brain%20development ; - :brain%20development ; - :brain%20development . - -### http://www.co-ode.org/ontologies/ont.owl#brain%20development - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#synapse - rdf:type owl:NamedIndividual , - ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission ; - :chemical%20synaptic%20transmission . - -### http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission - rdf:type owl:NamedIndividual , - ; - :cochlear%20degeneration . - -### http://www.co-ode.org/ontologies/ont.owl#cochlear%20degeneration - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + ; + ; + a , . + + ; + a , . + + , ; + , ; + , ; + , ; + ; + ; + a , . + + , ; + a , . + + a . + + a . + + a . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Upregulation of Thyroid Hormone Catabolism via Activation of Hepatic Nuclear Receptors, and Subsequent Adverse Neurodevelopmental Outcomes in Mammals"^^ . diff --git a/models/AOP_80.ttl b/models/AOP_80.ttl index d0d587dd..048087da 100644 --- a/models/AOP_80.ttl +++ b/models/AOP_80.ttl @@ -1,140 +1,88 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Acetylcholinesterase (AchE) Inhibition"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/FMA_67199 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0009611 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007568 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000051 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006281 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#Mitochondrial%20deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair ; - :DNA%20repair . - -### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair - rdf:type owl:NamedIndividual , - ; - :response%20to%20wounding . - -### http://www.co-ode.org/ontologies/ont.owl#Mitochondrial%20deoxyribonucleic%20acid - rdf:type owl:NamedIndividual , - ; - :response%20to%20wounding ; - :response%20to%20wounding ; - :response%20to%20wounding ; - :response%20to%20wounding . - -### http://www.co-ode.org/ontologies/ont.owl#response%20to%20wounding - rdf:type owl:NamedIndividual , - ; - :aging . - -### http://www.co-ode.org/ontologies/ont.owl#aging - rdf:type owl:NamedIndividual , - ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :thermoregulation%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#thermoregulation%20behavior - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure"^^ . diff --git a/models/AOP_81.ttl b/models/AOP_81.ttl index f19c6138..9cd12ec0 100644 --- a/models/AOP_81.ttl +++ b/models/AOP_81.ttl @@ -1,87 +1,53 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Acetylcholine accumulation in synapses"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/MP_0004889 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D013312 - rdf:type owl:Class . + a , . -### http://id.nlm.nih.gov/mesh/D001066 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#increased%20energy%20expenditure - rdf:type owl:NamedIndividual , - ; - :Appetite ; - :Appetite . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#Stress%2C%20Physiological - rdf:type owl:NamedIndividual , - ; - :Appetite . + a . -### http://www.co-ode.org/ontologies/ont.owl#Appetite - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms . + a . -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . + a . -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . + a . + ; + a , . + ; + ; + a , . -################################################################# -# Object Statements -################################################################# + ; + a , . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Increased metabolic stress contributes to abnormal foraging and leads to colony loss/failure"^^ . diff --git a/models/AOP_82.ttl b/models/AOP_82.ttl index ac675361..f04cd395 100644 --- a/models/AOP_82.ttl +++ b/models/AOP_82.ttl @@ -1,65 +1,34 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Respiratory distress/arrest"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0019098 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0001386 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/GO_0002164 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20behavior - rdf:type owl:NamedIndividual , - ; - :larval%20development . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20maternal%20nurturing - rdf:type owl:NamedIndividual , - ; - :larval%20development ; - :larval%20development . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#larval%20development - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . + a . -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . + ; + ; + a , . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Abnormal role change in worker caste contributes to reduced brood care and leads to colony loss/failure"^^ . diff --git a/models/AOP_84.ttl b/models/AOP_84.ttl index 0401e602..d147c64f 100644 --- a/models/AOP_84.ttl +++ b/models/AOP_84.ttl @@ -1,103 +1,71 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Dysregulation of heart rate and vascular tone"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/UBERON_0002405 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0044414 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002418 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0032502 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/NBO_0000051 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#immune%20system - rdf:type owl:NamedIndividual , - ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses . - -### http://www.co-ode.org/ontologies/ont.owl#suppression%20of%20host%20defenses - rdf:type owl:NamedIndividual , - ; - :increased%20susceptibility%20to%20viral%20infection . - -### http://www.co-ode.org/ontologies/ont.owl#increased%20susceptibility%20to%20viral%20infection - rdf:type owl:NamedIndividual , - ; - :developmental%20process ; - :developmental%20process . - -### http://www.co-ode.org/ontologies/ont.owl#developmental%20process - rdf:type owl:NamedIndividual , - ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :thermoregulation%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#thermoregulation%20behavior - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Suppression of immune system contributes to impaired development and leads to colony loss/failure"^^ . diff --git a/models/AOP_85.ttl b/models/AOP_85.ttl index 59105585..68228a67 100644 --- a/models/AOP_85.ttl +++ b/models/AOP_85.ttl @@ -1,95 +1,66 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Decrease, Population growth rate"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/UBERON_0002405 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0044414 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0002418 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PCO_0000001 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#immune%20system - rdf:type owl:NamedIndividual , - ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses ; - :suppression%20of%20host%20defenses . - -### http://www.co-ode.org/ontologies/ont.owl#suppression%20of%20host%20defenses - rdf:type owl:NamedIndividual , - ; - :increased%20susceptibility%20to%20viral%20infection . - -### http://www.co-ode.org/ontologies/ont.owl#increased%20susceptibility%20to%20viral%20infection - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior ; - :foraging%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms ; - :population%20of%20organisms . - -### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + a . + + ; + ; + ; + ; + a , . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + a , . + + ; + a , . + + "review"^^ ; + a ; + "Suppression of immune system contributes to abnormal foraging and leads to colony loss/failure"^^ . diff --git a/models/AOP_86.ttl b/models/AOP_86.ttl index aa3469f0..398f39c2 100644 --- a/models/AOP_86.ttl +++ b/models/AOP_86.ttl @@ -1,92 +1,54 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Binding, Thiol/seleno-proteins involved in protection against oxidative stress"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CHEBI_16217 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0046562 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/CHEBI_16240 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0050665 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000079 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002164 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . + a . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#D-glucono-1%2C5-lactone - rdf:type owl:NamedIndividual , - ; - :glucose%20oxidase%20activity ; - :glucose%20oxidase%20activity ; - :glucose%20oxidase%20activity ; - :glucose%20oxidase%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#glucose%20oxidase%20activity - rdf:type owl:NamedIndividual , - ; - :hydrogen%20peroxide%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#hydrogen%20peroxide - rdf:type owl:NamedIndividual , - ; - :hydrogen%20peroxide%20biosynthetic%20process . + a . -### http://www.co-ode.org/ontologies/ont.owl#hydrogen%20peroxide%20biosynthetic%20process - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#feeding%20behavior - rdf:type owl:NamedIndividual , - ; - :larval%20development . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#larval%20development - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . + ; + a , . + ; + a , . + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure"^^ . diff --git a/models/AOP_87.ttl b/models/AOP_87.ttl index a91e3016..23aa2d57 100644 --- a/models/AOP_87.ttl +++ b/models/AOP_87.ttl @@ -1,181 +1,106 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Oxidative Stress "^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005739 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D012380 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005488 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004978 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005516 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion ; - :mitochondrion . - -### http://www.co-ode.org/ontologies/ont.owl#mitochondrion - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding ; - :signaling ; - :signaling ; - :signaling ; - :signaling ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :role . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#role - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#calmodulin - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#calmodulin%20binding - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + , , ; + , , ; + , , ; + , , ; + a , . + + a . + + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + ; + ; + ; + ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + ; + ; + ; + ; + a , . + + "review"^^ ; + a ; + "Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure "^^ . diff --git a/models/AOP_88.ttl b/models/AOP_88.ttl index b74deeb3..ede51d5a 100644 --- a/models/AOP_88.ttl +++ b/models/AOP_88.ttl @@ -1,176 +1,92 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Glutamate dyshomeostasis"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030549 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030545 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005488 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004978 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005516 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activator%20activity ; - :receptor%20regulator%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activator%20activity - rdf:type owl:NamedIndividual , - ; - :binding ; - :signaling ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#receptor%20regulator%20activity - rdf:type owl:NamedIndividual , - ; - :binding ; - :signaling ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#calmodulin - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#calmodulin%20binding - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + , , ; + a , . + + , , ; + a , . + + "review"^^ ; + a ; + "Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure via abnormal role change within caste"^^ . diff --git a/models/AOP_89.ttl b/models/AOP_89.ttl index 9f48ba9b..55d5f17f 100644 --- a/models/AOP_89.ttl +++ b/models/AOP_89.ttl @@ -1,184 +1,97 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Cell injury/death"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0060756 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030549 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030545 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D012380 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/CHEBI_39124 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005488 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/PR_000004978 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0005516 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activator%20activity ; - :receptor%20regulator%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activator%20activity - rdf:type owl:NamedIndividual , - ; - :binding ; - :signaling ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#receptor%20regulator%20activity - rdf:type owl:NamedIndividual , - ; - :binding ; - :signaling ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :binding ; - :binding ; - :binding ; - :binding . - -### http://www.co-ode.org/ontologies/ont.owl#binding - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#calmodulin - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . - -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion - rdf:type owl:NamedIndividual , - ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding ; - :calmodulin%20binding . - -### http://www.co-ode.org/ontologies/ont.owl#calmodulin%20binding - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - ; - :foraging%20behavior . - -### http://www.co-ode.org/ontologies/ont.owl#foraging%20behavior - rdf:type owl:NamedIndividual , - ; - :role . - -### http://www.co-ode.org/ontologies/ont.owl#role - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . - -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + , ; + a , . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + , ; + a , . + + ; + ; + ; + ; + a , . + + , ; + a , . + + ; + a , . + + ; + a , . + + ; + a , . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + , , ; + a , . + + , , ; + a , . + + "review"^^ ; + a ; + "Nicotinic acetylcholine receptor activation followed by desensitization contributes to abnormal foraging and directly leads to colony loss/failure"^^ . diff --git a/models/AOP_90.ttl b/models/AOP_90.ttl index 427141a3..8f971a79 100644 --- a/models/AOP_90.ttl +++ b/models/AOP_90.ttl @@ -1,136 +1,78 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Neuroinflammation"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/FMA_61796 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0015464 - rdf:type owl:Class . -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019098 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001386 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0002164 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D056631 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030549 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0030545 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0099536 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity ; - :acetylcholine%20receptor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activity - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activator%20activity ; - :receptor%20regulator%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#Nicotinic%20acetylcholine%20receptor - rdf:type owl:NamedIndividual , - ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity ; - :acetylcholine%20receptor%20activator%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#acetylcholine%20receptor%20activator%20activity - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#receptor%20regulator%20activity - rdf:type owl:NamedIndividual , - ; - :synaptic%20signaling . - -### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling - rdf:type owl:NamedIndividual , - ; - :learning ; - :memory . - -### http://www.co-ode.org/ontologies/ont.owl#learning - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#memory - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#reproductive%20behavior - rdf:type owl:NamedIndividual , - ; - :larval%20development . + a . -### http://www.co-ode.org/ontologies/ont.owl#abnormal%20maternal%20nurturing - rdf:type owl:NamedIndividual , - ; - :larval%20development ; - :larval%20development . + a , . -### http://www.co-ode.org/ontologies/ont.owl#larval%20development - rdf:type owl:NamedIndividual , - ; - :colony%20collapse . + a . -### http://www.co-ode.org/ontologies/ont.owl#colony%20collapse - rdf:type owl:NamedIndividual , - . + a . + a . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + a . + + a . + + a . + + a . + + a . + + a . + + ; + a , . + + ; + a , . + + a . + + a . + + a . + + a . + + , ; + a , . + + a , . + + a , . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + ; + ; + a , . + + , ; + a , . + + a . + + a . + + ; + a , . + + ; + a , . + + "development"^^ ; + a ; + "Nicotinic acetylcholine receptor activation contributes to abnormal roll change within the worker bee caste leading to colony loss/failure 2"^^ . diff --git a/models/AOP_91.ttl b/models/AOP_91.ttl index d9ed137d..620c1801 100644 --- a/models/AOP_91.ttl +++ b/models/AOP_91.ttl @@ -1,102 +1,55 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decrease of neuronal network function"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000002095 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019871 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001508 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000079 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002120 - rdf:type owl:Class . + ; + a , . -### http://purl.obolibrary.org/obo/VT_0005372 - rdf:type owl:Class . + a . + a . + ; + a , . -################################################################# -# Individuals -################################################################# + , ; + , ; + , ; + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20protein%20type%201%20subunit%20alpha - rdf:type owl:NamedIndividual , - ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity . + a . -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20inhibitor%20activity - rdf:type owl:NamedIndividual , - ; - :action%20potential . + a . -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20protein%20type%201%20subunit%20alpha - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . + a , . -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :action%20potential . + a . -### http://www.co-ode.org/ontologies/ont.owl#action%20potential - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#feeding%20behavior - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#predatory%20behavior - rdf:type owl:NamedIndividual , - ; - :life%20span%20trait . + a , . -### http://www.co-ode.org/ontologies/ont.owl#life%20span%20trait - rdf:type owl:NamedIndividual , - . + a . + ; + a , . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Sodium channel inhibition leading to reduced survival"^^ . diff --git a/models/AOP_93.ttl b/models/AOP_93.ttl index 67970f0a..7bce1df7 100644 --- a/models/AOP_93.ttl +++ b/models/AOP_93.ttl @@ -1,82 +1,42 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Tissue resident cell activation"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0001508 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002120 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000002095 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019871 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . + ; + a , . + a . + a . -################################################################# -# Individuals -################################################################# + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20protein%20type%201%20subunit%20alpha - rdf:type owl:NamedIndividual , - ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity . + , ; + , ; + , ; + , ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20inhibitor%20activity - rdf:type owl:NamedIndividual , - ; - :action%20potential . + a . -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20protein%20type%201%20subunit%20alpha - rdf:type owl:NamedIndividual , - ; - :signaling ; - :signaling ; - :signaling ; - :signaling . + a . -### http://www.co-ode.org/ontologies/ont.owl#signaling - rdf:type owl:NamedIndividual , - ; - :action%20potential . + a , . -### http://www.co-ode.org/ontologies/ont.owl#action%20potential - rdf:type owl:NamedIndividual , - . + a . - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "sodium channel inhibition leading to increased predation"^^ . diff --git a/models/AOP_94.ttl b/models/AOP_94.ttl index 88aa9e07..e6519c61 100644 --- a/models/AOP_94.ttl +++ b/models/AOP_94.ttl @@ -1,114 +1,68 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Increased Pro-inflammatory mediators"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000002095 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019871 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0023052 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D054537 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D001919 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001954 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0005039 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/C565682 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0001508 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#atrioventricular%20block - rdf:type owl:NamedIndividual , - ; - :respiratory%20distress ; - :respiratory%20distress . - -### http://www.co-ode.org/ontologies/ont.owl#decreased%20heart%20rate - rdf:type owl:NamedIndividual , - ; - :respiratory%20distress ; - :respiratory%20distress . - -### http://www.co-ode.org/ontologies/ont.owl#respiratory%20distress - rdf:type owl:NamedIndividual , - ; - :hypoxia ; - :hypoxia . - -### http://www.co-ode.org/ontologies/ont.owl#hypoxia - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#action%20potential - rdf:type owl:NamedIndividual , - ; - :atrioventricular%20block ; - :atrioventricular%20block ; - :atrioventricular%20block ; - :atrioventricular%20block ; - :decreased%20heart%20rate ; - :decreased%20heart%20rate ; - :decreased%20heart%20rate ; - :decreased%20heart%20rate . - -### http://www.co-ode.org/ontologies/ont.owl#atrioventricular%20block - rdf:type owl:NamedIndividual , - ; - :respiratory%20distress ; - :respiratory%20distress . - -### http://www.co-ode.org/ontologies/ont.owl#decreased%20heart%20rate - rdf:type owl:NamedIndividual , - ; - :respiratory%20distress ; - :respiratory%20distress . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + , ; + , ; + , ; + , ; + a , . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + "review"^^ ; + a ; + "Sodium channel inhibition leading to congenital malformations"^^ . diff --git a/models/AOP_95.ttl b/models/AOP_95.ttl index a75228d2..24bd5303 100644 --- a/models/AOP_95.ttl +++ b/models/AOP_95.ttl @@ -1,64 +1,36 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decreased protection against oxidative stress"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/GO_0001508 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000371 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000079 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002120 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0005372 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_Q12809 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0019870 - rdf:type owl:Class . + a . + a , . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#life%20span%20trait - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#action%20potential - rdf:type owl:NamedIndividual , - . + a . + a . + a . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival"^^ . diff --git a/models/AOP_96.ttl b/models/AOP_96.ttl index adf9c503..3e5407e2 100644 --- a/models/AOP_96.ttl +++ b/models/AOP_96.ttl @@ -1,108 +1,68 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "Activation, PPARĪ±"^^xsd:string . - "review"^^xsd:string . - - -################################################################# -# Classes -################################################################# - -### http://purl.obolibrary.org/obo/PR_000002095 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0019871 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0051899 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0007269 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/GO_0006936 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001393 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0001399 - rdf:type owl:Class . - -### http://purl.obolibrary.org/obo/MP_0000753 - rdf:type owl:Class . - -### http://id.nlm.nih.gov/mesh/D009026 - rdf:type owl:Class . - - - -################################################################# -# Individuals -################################################################# - -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20protein%20type%201%20subunit%20alpha - rdf:type owl:NamedIndividual , - ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity ; - :sodium%20channel%20inhibitor%20activity . - -### http://www.co-ode.org/ontologies/ont.owl#sodium%20channel%20inhibitor%20activity - rdf:type owl:NamedIndividual , - ; - :membrane%20depolarization . - -### http://www.co-ode.org/ontologies/ont.owl#membrane%20depolarization - rdf:type owl:NamedIndividual , - ; - :neurotransmitter%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#neurotransmitter%20secretion - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#ataxia - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#hyperactivity - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#paralysis - rdf:type owl:NamedIndividual , - ; - :mortality ; - :mortality . - -### http://www.co-ode.org/ontologies/ont.owl#mortality - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a . + + a , . + + a . + + a . + + a . + + a . + + a . + + ; + ; + a , . + + ; + ; + a , . + + ; + ; + a , . + + a . + + a . + + ; + a , . + + ; + ; + ; + ; + a , . + + a . + + a . + + ; + a , . + + a . + + a , . + + "review"^^ ; + a ; + "Axonal sodium channel modulation leading to acute mortality"^^ . diff --git a/models/AOP_97.ttl b/models/AOP_97.ttl index 528de491..adf0928f 100644 --- a/models/AOP_97.ttl +++ b/models/AOP_97.ttl @@ -1,124 +1,58 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - - a owl:Ontology . - "impaired, Fertility"^^xsd:string . - "review"^^xsd:string . - -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000015189 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0098810 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0051610 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002120 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PCO_0000008 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/UBERON_0003978 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0050881 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000071 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0040011 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001820 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a , . -### http://www.co-ode.org/ontologies/ont.owl#predatory%20behavior - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#predatory%20behavior - rdf:type owl:NamedIndividual , - . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#valve - rdf:type owl:NamedIndividual , - ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement . + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#musculoskeletal%20movement - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#predatory%20behavior - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#fossorial%20locomotion%20behavior - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#fossorial%20locomotion%20behavior - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#locomotion - rdf:type owl:NamedIndividual , - . + a , . -### http://www.co-ode.org/ontologies/ont.owl#valve - rdf:type owl:NamedIndividual , - ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement ; - :musculoskeletal%20movement . + a , . -### http://www.co-ode.org/ontologies/ont.owl#musculoskeletal%20movement - rdf:type owl:NamedIndividual , - . - -### http://www.co-ode.org/ontologies/ont.owl#sodium-dependent%20serotonin%20transporter - rdf:type owl:NamedIndividual , - ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion . - -### http://www.co-ode.org/ontologies/ont.owl#serotonin%20secretion - rdf:type owl:NamedIndividual , - . - - - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "development"^^ ; + a ; + "5-hydroxytryptamine transporter (5-HTT; SERT) inhibition leading to population decline"^^ . diff --git a/models/AOP_98.ttl b/models/AOP_98.ttl index dd0d6b4c..ee55bb24 100644 --- a/models/AOP_98.ttl +++ b/models/AOP_98.ttl @@ -1,67 +1,38 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Decrease, Steroidogenic acute regulatory protein (STAR)"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/PR_000015189 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0098810 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0051610 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0001820 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/NBO_0000018 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/MP_0014039 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002120 - rdf:type owl:Class . + a . + a . + a , . -################################################################# -# Individuals -################################################################# + ; + ; + ; + ; + a , . -### http://www.co-ode.org/ontologies/ont.owl#sodium-dependent%20serotonin%20transporter - rdf:type owl:NamedIndividual , - ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion ; - :serotonin%20secretion . + a . -### http://www.co-ode.org/ontologies/ont.owl#serotonin%20secretion - rdf:type owl:NamedIndividual , - . + a . + a . - -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "5-hydroxytryptamine transporter (5-HTT; SERT) inhibition leading to decreased shelter seeking and increased predation"^^ . diff --git a/models/AOP_99.ttl b/models/AOP_99.ttl index 91ca9bd2..e40d3b5f 100644 --- a/models/AOP_99.ttl +++ b/models/AOP_99.ttl @@ -1,81 +1,48 @@ -@prefix owl: . - @prefix rdf: . - @prefix xml: . - @prefix xsd: . - @prefix rdfs: . - @prefix : . - @base . - a owl:Ontology . - "Reduction, Cholesterol transport in mitochondria"^^xsd:string . - "review"^^xsd:string . - + a . -################################################################# -# Classes -################################################################# + a . -### http://purl.obolibrary.org/obo/CL_0011110 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0043179 - rdf:type owl:Class . + a . -### http://id.nlm.nih.gov/mesh/D000758 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0040011 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/VT_0005372 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0002120 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/PR_000001423 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/GO_0004969 - rdf:type owl:Class . + a . -### http://purl.obolibrary.org/obo/GO_0007612 - rdf:type owl:Class . + a , . -### http://purl.obolibrary.org/obo/GO_0007613 - rdf:type owl:Class . + a . + a . + a . -################################################################# -# Individuals -################################################################# + a . -### http://www.co-ode.org/ontologies/ont.owl#life%20span%20trait - rdf:type owl:NamedIndividual , - . + a . -### http://www.co-ode.org/ontologies/ont.owl#histaminergic%20neuron - rdf:type owl:NamedIndividual , - ; - :rhythmic%20excitation ; - :rhythmic%20excitation ; - :rhythmic%20excitation ; - :rhythmic%20excitation . + a . -### http://www.co-ode.org/ontologies/ont.owl#rhythmic%20excitation - rdf:type owl:NamedIndividual , - . + a . + a . + ; + ; + ; + ; + a , . -################################################################# -# Object Statements -################################################################# - - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . - rdf:type owl:ObjectProperty . + "review"^^ ; + a ; + "Histamine (H2) receptor antagonism leading to reduced survival"^^ .