diff --git a/models/AOP_10_orig.ttl b/models/AOP_10_orig.ttl new file mode 100644 index 00000000..273c6540 --- /dev/null +++ b/models/AOP_10_orig.ttl @@ -0,0 +1,133 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Binding to the picrotoxin site of ionotropic GABA receptors leading to epileptic seizures in adult brain"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/CHEBI_17996 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0022851 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0051899 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/NBO_0000025 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000007766 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0050811 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000007770 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000007771 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007268 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0060079 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-1 + rdf:type owl:NamedIndividual , + ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding . + +### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding + rdf:type owl:NamedIndividual , + ; + :GABA-gated%20chloride%20ion%20channel%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-5 + rdf:type owl:NamedIndividual , + ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding . + +### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding + rdf:type owl:NamedIndividual , + ; + :GABA-gated%20chloride%20ion%20channel%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-6 + rdf:type owl:NamedIndividual , + ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding ; + :GABA%20receptor%20binding . + +### http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding + rdf:type owl:NamedIndividual , + ; + :GABA-gated%20chloride%20ion%20channel%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#chloride + rdf:type owl:NamedIndividual , + ; + :GABA-gated%20chloride%20ion%20channel%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#GABA-gated%20chloride%20ion%20channel%20activity + rdf:type owl:NamedIndividual , + ; + :chemical%20synaptic%20transmission . + +### http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission + rdf:type owl:NamedIndividual , + ; + :excitatory%20postsynaptic%20potential . + +### http://www.co-ode.org/ontologies/ont.owl#excitatory%20postsynaptic%20potential + rdf:type owl:NamedIndividual , + ; + :membrane%20depolarization . + +### http://www.co-ode.org/ontologies/ont.owl#membrane%20depolarization + rdf:type owl:NamedIndividual , + ; + :seizures . + +### http://www.co-ode.org/ontologies/ont.owl#seizures + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_12_orig.ttl b/models/AOP_12_orig.ttl new file mode 100644 index 00000000..4e6819ae --- /dev/null +++ b/models/AOP_12_orig.ttl @@ -0,0 +1,203 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Chronic binding of antagonist to N-methyl-D-aspartate receptors (NMDARs) during brain development leads to neurodegeneration with impairment in learning and memory in aging"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/GO_0017146 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004972 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0002229 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_39124 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006816 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000004716 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010467 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0046903 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008219 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000129 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0001847 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000127 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007612 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007613 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex + rdf:type owl:NamedIndividual , + ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity + rdf:type owl:NamedIndividual , + ; + :calcium%20ion%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion + rdf:type owl:NamedIndividual , + ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :secretion . + +### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :cell%20death . + +### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor + rdf:type owl:NamedIndividual , + ; + :secretion ; + :secretion ; + :secretion ; + :secretion . + +### http://www.co-ode.org/ontologies/ont.owl#secretion + rdf:type owl:NamedIndividual , + ; + :cell%20death . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20death + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :neurodegeneration ; + :neurodegeneration . + +### http://www.co-ode.org/ontologies/ont.owl#astrocyte + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :neurodegeneration ; + :neurodegeneration . + +### http://www.co-ode.org/ontologies/ont.owl#neurodegeneration + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#learning + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#memory + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :neurodegeneration ; + :neurodegeneration . + +### http://www.co-ode.org/ontologies/ont.owl#astrocyte + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :neurodegeneration ; + :neurodegeneration . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_131_orig.ttl b/models/AOP_131_orig.ttl new file mode 100644 index 00000000..dce1559e --- /dev/null +++ b/models/AOP_131_orig.ttl @@ -0,0 +1,150 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Aryl hydrocarbon receptor activation leading to uroporphyria"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000003858 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004874 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_27258 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000017134 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0003824 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_26214 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005654 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000006102 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010467 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_P79761 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor + rdf:type owl:NamedIndividual , + ; + :aryl%20hydrocarbon%20receptor%20activity ; + :aryl%20hydrocarbon%20receptor%20activity ; + :aryl%20hydrocarbon%20receptor%20activity ; + :aryl%20hydrocarbon%20receptor%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20activity + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#cytochrome%20P450%201A2 + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :uroporphyrinogen ; + :uroporphyrinogen ; + :uroporphyrinogen ; + :uroporphyrinogen . + +### http://www.co-ode.org/ontologies/ont.owl#cytochrome%20P450%201A5%20%28chicken%29 + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :uroporphyrinogen ; + :uroporphyrinogen ; + :uroporphyrinogen ; + :uroporphyrinogen . + +### http://www.co-ode.org/ontologies/ont.owl#uroporphyrinogen + rdf:type owl:NamedIndividual , + ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#uroporphyrinogen%20decarboxylase + rdf:type owl:NamedIndividual , + ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity + rdf:type owl:NamedIndividual , + ; + :porphyrins ; + :porphyrins ; + :porphyrins ; + :porphyrins . + +### http://www.co-ode.org/ontologies/ont.owl#porphyrins + rdf:type owl:NamedIndividual , + ; + :porphyria ; + :porphyria . + +### http://www.co-ode.org/ontologies/ont.owl#porphyria + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_13_orig.ttl b/models/AOP_13_orig.ttl new file mode 100644 index 00000000..5665270b --- /dev/null +++ b/models/AOP_13_orig.ttl @@ -0,0 +1,210 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Chronic binding of antagonist to N-methyl-D-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/CHEBI_39124 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006816 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0017146 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004972 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007612 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007613 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000004716 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010467 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0046903 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0030425 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048813 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0045202 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007416 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0099536 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_14321 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0014047 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008219 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex + rdf:type owl:NamedIndividual , + ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity + rdf:type owl:NamedIndividual , + ; + :calcium%20ion%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion + rdf:type owl:NamedIndividual , + ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :secretion . + +### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling + rdf:type owl:NamedIndividual , + ; + :learning ; + :memory . + +### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :cell%20death . + +### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor + rdf:type owl:NamedIndividual , + ; + :secretion ; + :secretion ; + :secretion ; + :secretion . + +### http://www.co-ode.org/ontologies/ont.owl#secretion + rdf:type owl:NamedIndividual , + ; + :cell%20death . + +### http://www.co-ode.org/ontologies/ont.owl#dendrite + rdf:type owl:NamedIndividual , + ; + :dendrite%20morphogenesis . + +### http://www.co-ode.org/ontologies/ont.owl#dendrite%20morphogenesis + rdf:type owl:NamedIndividual , + ; + :synapse%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#glutamate%281-%29 + rdf:type owl:NamedIndividual , + ; + :glutamate%20secretion ; + :glutamate%20secretion ; + :glutamate%20secretion ; + :glutamate%20secretion . + +### http://www.co-ode.org/ontologies/ont.owl#glutamate%20secretion + rdf:type owl:NamedIndividual , + ; + :synapse%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#synapse + rdf:type owl:NamedIndividual , + ; + :synapse%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#synapse%20assembly + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#synapse + rdf:type owl:NamedIndividual , + ; + :synapse%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#synapse%20assembly + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#learning + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#memory + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20death + rdf:type owl:NamedIndividual , + ; + :synapse%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#synapse + rdf:type owl:NamedIndividual , + ; + :synapse%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#synapse%20assembly + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_150_orig.ttl b/models/AOP_150_orig.ttl new file mode 100644 index 00000000..8d8daf60 --- /dev/null +++ b/models/AOP_150_orig.ttl @@ -0,0 +1,213 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Aryl hydrocarbon receptor activation leading to early life stage mortality, via reduced VEGF"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000003858 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004874 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0046983 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000004303 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000008555 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0003158 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0001544 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_0004535 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0072358 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0008762 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009026 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000017284 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010467 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0008469 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor + rdf:type owl:NamedIndividual , + ; + :aryl%20hydrocarbon%20receptor%20activity ; + :aryl%20hydrocarbon%20receptor%20activity ; + :aryl%20hydrocarbon%20receptor%20activity ; + :aryl%20hydrocarbon%20receptor%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20activity + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :abnormal%20protein%20level . + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :abnormal%20protein%20level . + +### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20A + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :endothelium%20development . + +### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20A + rdf:type owl:NamedIndividual , + ; + :abnormal%20protein%20level ; + :abnormal%20protein%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20protein%20level + rdf:type owl:NamedIndividual , + ; + :endothelium%20development ; + :endothelium%20development . + +### http://www.co-ode.org/ontologies/ont.owl#endothelium%20development + rdf:type owl:NamedIndividual , + ; + :abnormal%20cardiovascular%20system%20physiology ; + :cardiovascular%20system%20development . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20cardiovascular%20system%20physiology + rdf:type owl:NamedIndividual , + ; + :embryonic%20lethality ; + :embryonic%20lethality ; + :mortality ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#cardiovascular%20system + rdf:type owl:NamedIndividual , + ; + :cardiovascular%20system%20development ; + :cardiovascular%20system%20development ; + :cardiovascular%20system%20development ; + :cardiovascular%20system%20development . + +### http://www.co-ode.org/ontologies/ont.owl#cardiovascular%20system%20development + rdf:type owl:NamedIndividual , + ; + :embryonic%20lethality ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#embryonic%20lethality + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#mortality + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_154_orig.ttl b/models/AOP_154_orig.ttl new file mode 100644 index 00000000..2f62b32e --- /dev/null +++ b/models/AOP_154_orig.ttl @@ -0,0 +1,155 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Inhibition of Calcineurin Activity Leading to Impaired T-Cell Dependent Antibody Response"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000003112 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MI_0254 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000011161 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0002534 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0001775 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D007165 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000001379 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0032623 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000001391 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0032633 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000007535 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0005488 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/TAIR_AT5G64350 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#FK506-binding%20protein%2015 + rdf:type owl:NamedIndividual , + ; + :binding ; + :binding ; + :binding ; + :binding . + +### http://www.co-ode.org/ontologies/ont.owl#binding + rdf:type owl:NamedIndividual , + ; + :genetic%20interference . + +### http://www.co-ode.org/ontologies/ont.owl#FKBP12%20%28Arabidopsis%20thaliana%29 + rdf:type owl:NamedIndividual , + ; + :binding ; + :binding ; + :binding ; + :binding . + +### http://www.co-ode.org/ontologies/ont.owl#binding + rdf:type owl:NamedIndividual , + ; + :genetic%20interference . + +### http://www.co-ode.org/ontologies/ont.owl#NFAT%20protein + rdf:type owl:NamedIndividual , + ; + :genetic%20interference . + +### http://www.co-ode.org/ontologies/ont.owl#genetic%20interference + rdf:type owl:NamedIndividual , + ; + :cytokine%20production%20involved%20in%20inflammatory%20response ; + :cell%20activation . + +### http://www.co-ode.org/ontologies/ont.owl#NFAT%20activation%20molecule%201 + rdf:type owl:NamedIndividual , + ; + :cytokine%20production%20involved%20in%20inflammatory%20response ; + :cytokine%20production%20involved%20in%20inflammatory%20response ; + :cytokine%20production%20involved%20in%20inflammatory%20response ; + :cytokine%20production%20involved%20in%20inflammatory%20response . + +### http://www.co-ode.org/ontologies/ont.owl#cytokine%20production%20involved%20in%20inflammatory%20response + rdf:type owl:NamedIndividual , + ; + :interleukin-2%20production ; + :interleukin-4%20production . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20activation + rdf:type owl:NamedIndividual , + ; + :interleukin-2%20production ; + :interleukin-4%20production . + +### http://www.co-ode.org/ontologies/ont.owl#interleukin-2 + rdf:type owl:NamedIndividual , + ; + :interleukin-2%20production . + +### http://www.co-ode.org/ontologies/ont.owl#interleukin-2%20production + rdf:type owl:NamedIndividual , + ; + :Immunosuppression . + +### http://www.co-ode.org/ontologies/ont.owl#interleukin-4 + rdf:type owl:NamedIndividual , + ; + :interleukin-4%20production . + +### http://www.co-ode.org/ontologies/ont.owl#interleukin-4%20production + rdf:type owl:NamedIndividual , + ; + :Immunosuppression . + +### http://www.co-ode.org/ontologies/ont.owl#Immunosuppression + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_155_orig.ttl b/models/AOP_155_orig.ttl new file mode 100644 index 00000000..04b1a557 --- /dev/null +++ b/models/AOP_155_orig.ttl @@ -0,0 +1,126 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Deiodinase 2 inhibition leading to increased mortality via reduced posterior swim bladder inflation"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000006481 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0003824 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_28774 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005418 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_2001278 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048798 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/NBO_0000371 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000001 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000008 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009026 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#type%20II%20iodothyronine%20deiodinase + rdf:type owl:NamedIndividual , + ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#posterior%20chamber%20swim%20bladder + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation + rdf:type owl:NamedIndividual , + ; + :aquatic%20locomotion . + +### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion + rdf:type owl:NamedIndividual , + ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#mortality + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_156_orig.ttl b/models/AOP_156_orig.ttl new file mode 100644 index 00000000..1835df91 --- /dev/null +++ b/models/AOP_156_orig.ttl @@ -0,0 +1,126 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Deiodinase 2 inhibition leading to increased mortality via reduced anterior swim bladder inflation"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000006481 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0003824 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000001 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000008 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_28774 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005418 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_2001277 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048798 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/NBO_0000371 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009026 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#type%20II%20iodothyronine%20deiodinase + rdf:type owl:NamedIndividual , + ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#anterior%20chamber%20swim%20bladder + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation + rdf:type owl:NamedIndividual , + ; + :aquatic%20locomotion . + +### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion + rdf:type owl:NamedIndividual , + ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#mortality + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_157_orig.ttl b/models/AOP_157_orig.ttl new file mode 100644 index 00000000..019abe41 --- /dev/null +++ b/models/AOP_157_orig.ttl @@ -0,0 +1,126 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Deiodinase 1 inhibition leading to increased mortality via reduced posterior swim bladder inflation "^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000006480 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0003824 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000001 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000008 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_28774 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005418 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_2001278 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048798 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/NBO_0000371 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009026 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#type%20I%20iodothyronine%20deiodinase + rdf:type owl:NamedIndividual , + ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#posterior%20chamber%20swim%20bladder + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation + rdf:type owl:NamedIndividual , + ; + :aquatic%20locomotion . + +### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion + rdf:type owl:NamedIndividual , + ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#mortality + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_158_orig.ttl b/models/AOP_158_orig.ttl new file mode 100644 index 00000000..16775b75 --- /dev/null +++ b/models/AOP_158_orig.ttl @@ -0,0 +1,126 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Deiodinase 1 inhibition leading to increased mortality via reduced anterior swim bladder inflation"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000006480 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0003824 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000001 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000008 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_28774 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005418 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_2001277 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048798 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/NBO_0000371 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009026 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#type%20I%20iodothyronine%20deiodinase + rdf:type owl:NamedIndividual , + ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity ; + :catalytic%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#catalytic%20activity + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#anterior%20chamber%20swim%20bladder + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation + rdf:type owl:NamedIndividual , + ; + :aquatic%20locomotion . + +### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion + rdf:type owl:NamedIndividual , + ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#mortality + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_159_orig.ttl b/models/AOP_159_orig.ttl new file mode 100644 index 00000000..d27e2e52 --- /dev/null +++ b/models/AOP_159_orig.ttl @@ -0,0 +1,161 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Thyroperoxidase inhibition leading to increased mortality via reduced anterior swim bladder inflation"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000016584 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004447 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000001 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000008 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_60311 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006590 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_30660 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005475 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_2001277 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048798 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/NBO_0000371 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_28774 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005418 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009026 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase + rdf:type owl:NamedIndividual , + ; + :iodide%20peroxidase%20activity ; + :iodide%20peroxidase%20activity ; + :iodide%20peroxidase%20activity ; + :iodide%20peroxidase%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity + rdf:type owl:NamedIndividual , + ; + :thyroid%20hormone%20generation . + +### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone + rdf:type owl:NamedIndividual , + ; + :thyroid%20hormone%20generation . + +### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20thyroxine%20level . + +### http://www.co-ode.org/ontologies/ont.owl#thyroxine + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20thyroxine%20level ; + :abnormal%20circulating%20thyroxine%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#3%2C3%27%2C5%27-triiodothyronine + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20hormone%20level ; + :abnormal%20circulating%20hormone%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20hormone%20level + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#anterior%20chamber%20swim%20bladder + rdf:type owl:NamedIndividual , + ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation ; + :swim%20bladder%20inflation . + +### http://www.co-ode.org/ontologies/ont.owl#swim%20bladder%20inflation + rdf:type owl:NamedIndividual , + ; + :aquatic%20locomotion . + +### http://www.co-ode.org/ontologies/ont.owl#aquatic%20locomotion + rdf:type owl:NamedIndividual , + ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#mortality + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_15_orig.ttl b/models/AOP_15_orig.ttl new file mode 100644 index 00000000..bbadc885 --- /dev/null +++ b/models/AOP_15_orig.ttl @@ -0,0 +1,92 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Alkylation of DNA in male pre-meiotic germ cells leading to heritable mutations"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/CHEBI_16991 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009154 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006305 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006281 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid + rdf:type owl:NamedIndividual , + ; + :DNA%20alkylation ; + :DNA%20alkylation ; + :DNA%20alkylation ; + :DNA%20alkylation . + +### http://www.co-ode.org/ontologies/ont.owl#DNA%20alkylation + rdf:type owl:NamedIndividual , + ; + :DNA%20repair . + +### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid + rdf:type owl:NamedIndividual , + ; + :DNA%20repair ; + :DNA%20repair ; + :DNA%20repair ; + :DNA%20repair . + +### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair + rdf:type owl:NamedIndividual , + ; + :mutation . + +### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid + rdf:type owl:NamedIndividual , + ; + :mutation . + +### http://www.co-ode.org/ontologies/ont.owl#mutation + rdf:type owl:NamedIndividual , + ; + :mutation . + +### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid + rdf:type owl:NamedIndividual , + ; + :mutation . + +### http://www.co-ode.org/ontologies/ont.owl#mutation + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_17_orig.ttl b/models/AOP_17_orig.ttl new file mode 100644 index 00000000..4b37f548 --- /dev/null +++ b/models/AOP_17_orig.ttl @@ -0,0 +1,118 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins involved in protection against oxidative stress during brain development leads to impairment of learning and memory"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/GO_0008219 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000129 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0001847 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000127 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0099536 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007612 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007613 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0002263 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0002526 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#cell%20death + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :cell%20death ; + :cell%20death . + +### http://www.co-ode.org/ontologies/ont.owl#astrocyte + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :cell%20death ; + :cell%20death . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20death + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20death + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling + rdf:type owl:NamedIndividual , + ; + :learning ; + :memory . + +### http://www.co-ode.org/ontologies/ont.owl#learning + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#memory + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_202_orig.ttl b/models/AOP_202_orig.ttl new file mode 100644 index 00000000..fa3d5a39 --- /dev/null +++ b/models/AOP_202_orig.ttl @@ -0,0 +1,43 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Inhibitor binding to topoisomerase II leading to infant leukaemia"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/GO_0061505 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D014178 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#DNA%20topoisomerase%20II%20activity + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#Translocation%2C%20Genetic + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + diff --git a/models/AOP_212_orig.ttl b/models/AOP_212_orig.ttl new file mode 100644 index 00000000..8b4b83a9 --- /dev/null +++ b/models/AOP_212_orig.ttl @@ -0,0 +1,133 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Histone deacetylase inhibition leading to testicular atrophy"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000008478 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004857 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_15358 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0031399 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000029191 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0051726 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006915 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/FMA_7210 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/HP_0000029 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000017 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#histone%20deacetylase%201 + rdf:type owl:NamedIndividual , + ; + :enzyme%20inhibitor%20activity ; + :enzyme%20inhibitor%20activity ; + :enzyme%20inhibitor%20activity ; + :enzyme%20inhibitor%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#enzyme%20inhibitor%20activity + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20protein%20modification%20process . + +### http://www.co-ode.org/ontologies/ont.owl#histone + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20protein%20modification%20process ; + :regulation%20of%20protein%20modification%20process ; + :regulation%20of%20protein%20modification%20process ; + :regulation%20of%20protein%20modification%20process . + +### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20protein%20modification%20process + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20cell%20cycle . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20cycle-related%20cyclin + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20cell%20cycle ; + :regulation%20of%20cell%20cycle ; + :regulation%20of%20cell%20cycle ; + :regulation%20of%20cell%20cycle . + +### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20cell%20cycle + rdf:type owl:NamedIndividual , + ; + :apoptotic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#apoptotic%20process + rdf:type owl:NamedIndividual , + ; + :spermatocyte ; + :spermatocyte ; + :spermatocyte ; + :spermatocyte . + +### http://www.co-ode.org/ontologies/ont.owl#spermatocyte + rdf:type owl:NamedIndividual , + ; + :Testicular%20atrophy ; + :Testicular%20atrophy . + +### http://www.co-ode.org/ontologies/ont.owl#Testis + rdf:type owl:NamedIndividual , + ; + :Testicular%20atrophy ; + :Testicular%20atrophy . + +### http://www.co-ode.org/ontologies/ont.owl#Testicular%20atrophy + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_21_orig.ttl b/models/AOP_21_orig.ttl new file mode 100644 index 00000000..486ec987 --- /dev/null +++ b/models/AOP_21_orig.ttl @@ -0,0 +1,140 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Aryl hydrocarbon receptor activation leading to early life stage mortality, via increased COX-2"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000003858 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004874 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0046983 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000004303 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0001544 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_0004535 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0072358 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000013428 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010467 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0008762 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009026 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity + rdf:type owl:NamedIndividual , + ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#aryl%20hydrocarbon%20receptor%20nuclear%20translocator + rdf:type owl:NamedIndividual , + ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity ; + :protein%20dimerization%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20dimerization%20activity + rdf:type owl:NamedIndividual , + ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#prostaglandin%20G/H%20synthase%202 + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :abnormal%20cardiovascular%20system%20physiology ; + :cardiovascular%20system%20development . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20cardiovascular%20system%20physiology + rdf:type owl:NamedIndividual , + ; + :embryonic%20lethality ; + :embryonic%20lethality ; + :mortality ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#cardiovascular%20system + rdf:type owl:NamedIndividual , + ; + :cardiovascular%20system%20development ; + :cardiovascular%20system%20development ; + :cardiovascular%20system%20development ; + :cardiovascular%20system%20development . + +### http://www.co-ode.org/ontologies/ont.owl#cardiovascular%20system%20development + rdf:type owl:NamedIndividual , + ; + :embryonic%20lethality ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#embryonic%20lethality + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#mortality + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_220_orig.ttl b/models/AOP_220_orig.ttl new file mode 100644 index 00000000..e2356c2f --- /dev/null +++ b/models/AOP_220_orig.ttl @@ -0,0 +1,83 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Cyp2E1 Activation Leading to Liver Cancer"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/GO_0034599 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000235 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0002281 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000008555 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005039 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000017294 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#cellular%20response%20to%20oxidative%20stress + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#macrophage + rdf:type owl:NamedIndividual , + ; + :macrophage%20activation%20involved%20in%20immune%20response . + +### http://www.co-ode.org/ontologies/ont.owl#macrophage%20activation%20involved%20in%20immune%20response + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#hypoxia-inducible%20factor%201-alpha + rdf:type owl:NamedIndividual , + ; + :hypoxia ; + :hypoxia . + +### http://www.co-ode.org/ontologies/ont.owl#hypoxia + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#von%20Hippel-Lindau%20disease%20tumor%20suppressor + rdf:type owl:NamedIndividual , + ; + :hypoxia ; + :hypoxia . + +### http://www.co-ode.org/ontologies/ont.owl#hypoxia + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_23_orig.ttl b/models/AOP_23_orig.ttl new file mode 100644 index 00000000..85d75d11 --- /dev/null +++ b/models/AOP_23_orig.ttl @@ -0,0 +1,243 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Androgen receptor agonism leading to reproductive dysfunction (in repeat-spawning fish)"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PCO_0000001 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000008 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000004191 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004882 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_17347 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0061370 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_16469 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006703 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D014819 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010467 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0009306 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/VT_1000294 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006898 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0001555 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048599 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_81568 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_81569 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor + rdf:type owl:NamedIndividual , + ; + :androgen%20receptor%20activity ; + :androgen%20receptor%20activity ; + :androgen%20receptor%20activity ; + :androgen%20receptor%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#androgen%20receptor%20activity + rdf:type owl:NamedIndividual , + ; + :Luteinizing%20hormone ; + :Luteinizing%20hormone ; + :Luteinizing%20hormone ; + :Luteinizing%20hormone ; + :Follicle%20stimulating%20hormone ; + :Follicle%20stimulating%20hormone ; + :Follicle%20stimulating%20hormone ; + :Follicle%20stimulating%20hormone . + +### http://www.co-ode.org/ontologies/ont.owl#Luteinizing%20hormone + rdf:type owl:NamedIndividual , + ; + :testosterone%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#Follicle%20stimulating%20hormone + rdf:type owl:NamedIndividual , + ; + :testosterone%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#testosterone + rdf:type owl:NamedIndividual , + ; + :testosterone%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#testosterone%20biosynthetic%20process + rdf:type owl:NamedIndividual , + ; + :estrogen%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol + rdf:type owl:NamedIndividual , + ; + :estrogen%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process + rdf:type owl:NamedIndividual , + ; + :17beta-estradiol ; + :17beta-estradiol ; + :17beta-estradiol ; + :17beta-estradiol . + +### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :protein%20secretion ; + :protein%20secretion ; + :protein%20secretion ; + :protein%20secretion . + +### http://www.co-ode.org/ontologies/ont.owl#vitellogenins + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :vitellogenins ; + :vitellogenins ; + :vitellogenins ; + :vitellogenins . + +### http://www.co-ode.org/ontologies/ont.owl#vitellogenins + rdf:type owl:NamedIndividual , + ; + :protein%20secretion ; + :protein%20secretion ; + :protein%20secretion ; + :protein%20secretion . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20secretion + rdf:type owl:NamedIndividual , + ; + :vitellogenins ; + :vitellogenins ; + :vitellogenins ; + :vitellogenins . + +### http://www.co-ode.org/ontologies/ont.owl#vitellogenins + rdf:type owl:NamedIndividual , + ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :oocyte%20growth ; + :oocyte%20growth ; + :oocyte%20growth ; + :oocyte%20growth ; + :oocyte%20development ; + :oocyte%20development ; + :oocyte%20development ; + :oocyte%20development . + +### http://www.co-ode.org/ontologies/ont.owl#vitellogenins + rdf:type owl:NamedIndividual , + ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis . + +### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis + rdf:type owl:NamedIndividual , + ; + :egg%20quantity . + +### http://www.co-ode.org/ontologies/ont.owl#oocyte%20growth + rdf:type owl:NamedIndividual , + ; + :egg%20quantity . + +### http://www.co-ode.org/ontologies/ont.owl#oocyte%20development + rdf:type owl:NamedIndividual , + ; + :egg%20quantity . + +### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_25_orig.ttl b/models/AOP_25_orig.ttl new file mode 100644 index 00000000..b1a04e7a --- /dev/null +++ b/models/AOP_25_orig.ttl @@ -0,0 +1,201 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Aromatase inhibition leading to reproductive dysfunction"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PCO_0000001 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PCO_0000008 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000006100 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0070330 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_16469 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D014819 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010467 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0009306 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006898 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0001555 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048599 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006703 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/VT_1000294 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#aromatase + rdf:type owl:NamedIndividual , + ; + :aromatase%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#aromatase%20activity + rdf:type owl:NamedIndividual , + ; + :estrogen%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol + rdf:type owl:NamedIndividual , + ; + :estrogen%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#estrogen%20biosynthetic%20process + rdf:type owl:NamedIndividual , + ; + :17beta-estradiol ; + :17beta-estradiol ; + :17beta-estradiol ; + :17beta-estradiol . + +### http://www.co-ode.org/ontologies/ont.owl#17beta-estradiol + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :protein%20secretion ; + :protein%20secretion ; + :protein%20secretion ; + :protein%20secretion . + +### http://www.co-ode.org/ontologies/ont.owl#vitellogenins + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :vitellogenins ; + :vitellogenins ; + :vitellogenins ; + :vitellogenins . + +### http://www.co-ode.org/ontologies/ont.owl#vitellogenins + rdf:type owl:NamedIndividual , + ; + :protein%20secretion ; + :protein%20secretion ; + :protein%20secretion ; + :protein%20secretion . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20secretion + rdf:type owl:NamedIndividual , + ; + :vitellogenins ; + :vitellogenins ; + :vitellogenins ; + :vitellogenins . + +### http://www.co-ode.org/ontologies/ont.owl#population%20of%20organisms + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#population%20growth%20rate + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#egg%20quantity + rdf:type owl:NamedIndividual , + ; + :population%20growth%20rate ; + :population%20growth%20rate . + +### http://www.co-ode.org/ontologies/ont.owl#vitellogenins + rdf:type owl:NamedIndividual , + ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis . + +### http://www.co-ode.org/ontologies/ont.owl#receptor-mediated%20endocytosis + rdf:type owl:NamedIndividual , + ; + :egg%20quantity . + +### http://www.co-ode.org/ontologies/ont.owl#oocyte%20growth + rdf:type owl:NamedIndividual , + ; + :egg%20quantity . + +### http://www.co-ode.org/ontologies/ont.owl#oocyte%20development + rdf:type owl:NamedIndividual , + ; + :egg%20quantity . + +### http://www.co-ode.org/ontologies/ont.owl#vitellogenins + rdf:type owl:NamedIndividual , + ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :receptor-mediated%20endocytosis ; + :oocyte%20growth ; + :oocyte%20growth ; + :oocyte%20growth ; + :oocyte%20growth ; + :oocyte%20development ; + :oocyte%20development ; + :oocyte%20development ; + :oocyte%20development . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_263_orig.ttl b/models/AOP_263_orig.ttl new file mode 100644 index 00000000..d95d1a88 --- /dev/null +++ b/models/AOP_263_orig.ttl @@ -0,0 +1,135 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/GO_0005739 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_1901691 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0017077 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0051881 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_0000468 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0040007 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_15422 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006754 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0005623 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008283 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#mitochondrion + rdf:type owl:NamedIndividual , + ; + :proton%20binding ; + :proton%20binding ; + :proton%20binding ; + :proton%20binding . + +### http://www.co-ode.org/ontologies/ont.owl#proton%20binding + rdf:type owl:NamedIndividual , + ; + :ATP%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#mitochondrion + rdf:type owl:NamedIndividual , + ; + :oxidative%20phosphorylation%20uncoupler%20activity ; + :oxidative%20phosphorylation%20uncoupler%20activity ; + :oxidative%20phosphorylation%20uncoupler%20activity ; + :oxidative%20phosphorylation%20uncoupler%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#oxidative%20phosphorylation%20uncoupler%20activity + rdf:type owl:NamedIndividual , + ; + :ATP%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#mitochondrion + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20mitochondrial%20membrane%20potential ; + :regulation%20of%20mitochondrial%20membrane%20potential ; + :regulation%20of%20mitochondrial%20membrane%20potential ; + :regulation%20of%20mitochondrial%20membrane%20potential . + +### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20mitochondrial%20membrane%20potential + rdf:type owl:NamedIndividual , + ; + :ATP%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#ATP + rdf:type owl:NamedIndividual , + ; + :ATP%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#ATP%20biosynthetic%20process + rdf:type owl:NamedIndividual , + ; + :cell%20proliferation . + +### http://www.co-ode.org/ontologies/ont.owl#cell + rdf:type owl:NamedIndividual , + ; + :cell%20proliferation . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation + rdf:type owl:NamedIndividual , + ; + :growth . + +### http://www.co-ode.org/ontologies/ont.owl#multicellular%20organism + rdf:type owl:NamedIndividual , + ; + :growth ; + :growth ; + :growth ; + :growth . + +### http://www.co-ode.org/ontologies/ont.owl#growth + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_277_orig.ttl b/models/AOP_277_orig.ttl new file mode 100644 index 00000000..4173e7f1 --- /dev/null +++ b/models/AOP_277_orig.ttl @@ -0,0 +1,51 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000001753 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007249 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#transcription%20factor%20NF-kappa-B%20subunit + rdf:type owl:NamedIndividual , + ; + :I-kappaB%20kinase%2FNF-kappaB%20signaling ; + :I-kappaB%20kinase%2FNF-kappaB%20signaling ; + :I-kappaB%20kinase%2FNF-kappaB%20signaling ; + :I-kappaB%20kinase%2FNF-kappaB%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#I-kappaB%20kinase/NF-kappaB%20signaling + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_296_orig.ttl b/models/AOP_296_orig.ttl new file mode 100644 index 00000000..e680228e --- /dev/null +++ b/models/AOP_296_orig.ttl @@ -0,0 +1,95 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Oxidative DNA damage leading to chromosomal aberrations and mutations"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/CHEBI_26523 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_1901031 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_16991 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006281 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009154 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#reactive%20oxygen%20species + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20response%20to%20reactive%20oxygen%20species ; + :regulation%20of%20response%20to%20reactive%20oxygen%20species ; + :regulation%20of%20response%20to%20reactive%20oxygen%20species ; + :regulation%20of%20response%20to%20reactive%20oxygen%20species . + +### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20response%20to%20reactive%20oxygen%20species + rdf:type owl:NamedIndividual , + ; + :DNA%20repair . + +### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid + rdf:type owl:NamedIndividual , + ; + :DNA%20repair ; + :DNA%20repair ; + :DNA%20repair ; + :DNA%20repair . + +### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid + rdf:type owl:NamedIndividual , + ; + :DNA%20repair ; + :DNA%20repair ; + :DNA%20repair ; + :DNA%20repair . + +### http://www.co-ode.org/ontologies/ont.owl#DNA%20repair + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#deoxyribonucleic%20acid + rdf:type owl:NamedIndividual , + ; + :mutation . + +### http://www.co-ode.org/ontologies/ont.owl#mutation + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_360_orig.ttl b/models/AOP_360_orig.ttl new file mode 100644 index 00000000..6fbc0c24 --- /dev/null +++ b/models/AOP_360_orig.ttl @@ -0,0 +1,71 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Chitin synthase 1 inhibition leading to mortality"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/GO_0004100 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_0001002 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0042335 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0018990 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009026 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#chitin%20synthase%20activity + rdf:type owl:NamedIndividual , + ; + :cuticle%20development . + +### http://www.co-ode.org/ontologies/ont.owl#cuticle + rdf:type owl:NamedIndividual , + ; + :cuticle%20development . + +### http://www.co-ode.org/ontologies/ont.owl#cuticle%20development + rdf:type owl:NamedIndividual , + ; + :ecdysis%2C%20chitin-based%20cuticle . + +### http://www.co-ode.org/ontologies/ont.owl#ecdysis%2C%20chitin-based%20cuticle + rdf:type owl:NamedIndividual , + ; + :mortality . + +### http://www.co-ode.org/ontologies/ont.owl#mortality + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_38_orig.ttl b/models/AOP_38_orig.ttl new file mode 100644 index 00000000..4a9844d8 --- /dev/null +++ b/models/AOP_38_orig.ttl @@ -0,0 +1,119 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Protein Alkylation leading to Liver Fibrosis"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/UBERON_0002107 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0003333 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008213 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008219 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000632 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0035733 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_3815 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0032964 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0002263 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0002526 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#protein%20alkylation + rdf:type owl:NamedIndividual , + ; + :cell%20death . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20death + rdf:type owl:NamedIndividual , + ; + :cell%20activation%20involved%20in%20immune%20response . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20activation%20involved%20in%20immune%20response + rdf:type owl:NamedIndividual , + ; + :acute%20inflammatory%20response . + +### http://www.co-ode.org/ontologies/ont.owl#acute%20inflammatory%20response + rdf:type owl:NamedIndividual , + ; + :hepatic%20stellate%20cell%20activation . + +### http://www.co-ode.org/ontologies/ont.owl#hepatic%20stellate%20cell + rdf:type owl:NamedIndividual , + ; + :hepatic%20stellate%20cell%20activation ; + :hepatic%20stellate%20cell%20activation ; + :hepatic%20stellate%20cell%20activation ; + :hepatic%20stellate%20cell%20activation . + +### http://www.co-ode.org/ontologies/ont.owl#hepatic%20stellate%20cell%20activation + rdf:type owl:NamedIndividual , + ; + :collagen%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#collagen + rdf:type owl:NamedIndividual , + ; + :collagen%20biosynthetic%20process . + +### http://www.co-ode.org/ontologies/ont.owl#collagen%20biosynthetic%20process + rdf:type owl:NamedIndividual , + ; + :liver%20fibrosis . + +### http://www.co-ode.org/ontologies/ont.owl#liver + rdf:type owl:NamedIndividual , + ; + :liver%20fibrosis ; + :liver%20fibrosis . + +### http://www.co-ode.org/ontologies/ont.owl#liver%20fibrosis + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_3_orig.ttl b/models/AOP_3_orig.ttl new file mode 100644 index 00000000..e861961b --- /dev/null +++ b/models/AOP_3_orig.ttl @@ -0,0 +1,149 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000031316 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008137 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006120 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0005739 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_36080 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D057165 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000129 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0001847 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000127 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0003244 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D020734 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#mitochondrion + rdf:type owl:NamedIndividual , + ; + :Proteostasis%20deficiencies . + +### http://www.co-ode.org/ontologies/ont.owl#protein + rdf:type owl:NamedIndividual , + ; + :Proteostasis%20deficiencies . + +### http://www.co-ode.org/ontologies/ont.owl#Proteostasis%20deficiencies + rdf:type owl:NamedIndividual , + ; + :loss%20of%20dopaminergic%20neurons . + +### http://www.co-ode.org/ontologies/ont.owl#loss%20of%20dopaminergic%20neurons + rdf:type owl:NamedIndividual , + ; + :Parkinsonian%20disorders . + +### http://www.co-ode.org/ontologies/ont.owl#loss%20of%20dopaminergic%20neurons + rdf:type owl:NamedIndividual , + ; + :Parkinsonian%20disorders . + +### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :loss%20of%20dopaminergic%20neurons ; + :loss%20of%20dopaminergic%20neurons . + +### http://www.co-ode.org/ontologies/ont.owl#astrocyte + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :loss%20of%20dopaminergic%20neurons ; + :loss%20of%20dopaminergic%20neurons . + +### http://www.co-ode.org/ontologies/ont.owl#Parkinsonian%20disorders + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#NADH-ubiquinone%20oxidoreductase%20chain%201 + rdf:type owl:NamedIndividual , + ; + :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; + :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; + :NADH%20dehydrogenase%20%28ubiquinone%29%20activity ; + :NADH%20dehydrogenase%20%28ubiquinone%29%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#NADH%20dehydrogenase%20%28ubiquinone%29%20activity + rdf:type owl:NamedIndividual , + ; + :mitochondrion ; + :mitochondrion ; + :mitochondrion ; + :mitochondrion . + +### http://www.co-ode.org/ontologies/ont.owl#mitochondrion + rdf:type owl:NamedIndividual , + ; + :Proteostasis%20deficiencies . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_40_orig.ttl b/models/AOP_40_orig.ttl new file mode 100644 index 00000000..8e96a853 --- /dev/null +++ b/models/AOP_40_orig.ttl @@ -0,0 +1,138 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Covalent Protein binding leading to Skin Sensitisation"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/CHEBI_59739 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0005515 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0032980 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0002534 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0001775 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0002396 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000084 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0042110 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000813 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008283 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#electrophilic%20reagant + rdf:type owl:NamedIndividual , + ; + :protein%20binding ; + :protein%20binding ; + :protein%20binding ; + :protein%20binding . + +### http://www.co-ode.org/ontologies/ont.owl#protein%20binding + rdf:type owl:NamedIndividual , + ; + :cell%20activation ; + :MHC%20protein%20complex%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#keratinocyte%20activation + rdf:type owl:NamedIndividual , + ; + :cell%20activation ; + :MHC%20protein%20complex%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#cytokine%20production%20involved%20in%20inflammatory%20response + rdf:type owl:NamedIndividual , + ; + :cell%20activation ; + :MHC%20protein%20complex%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20activation + rdf:type owl:NamedIndividual , + ; + :T%20cell%20activation ; + :cell%20proliferation . + +### http://www.co-ode.org/ontologies/ont.owl#MHC%20protein%20complex%20assembly + rdf:type owl:NamedIndividual , + ; + :T%20cell%20activation ; + :cell%20proliferation . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20activation + rdf:type owl:NamedIndividual , + ; + :T%20cell%20activation ; + :cell%20proliferation . + +### http://www.co-ode.org/ontologies/ont.owl#MHC%20protein%20complex%20assembly + rdf:type owl:NamedIndividual , + ; + :T%20cell%20activation ; + :cell%20proliferation . + +### http://www.co-ode.org/ontologies/ont.owl#T%20cell + rdf:type owl:NamedIndividual , + ; + :T%20cell%20activation ; + :T%20cell%20activation ; + :T%20cell%20activation ; + :T%20cell%20activation . + +### http://www.co-ode.org/ontologies/ont.owl#T%20cell%20activation + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#memory%20T%20cell + rdf:type owl:NamedIndividual , + ; + :cell%20proliferation ; + :cell%20proliferation ; + :cell%20proliferation ; + :cell%20proliferation . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20proliferation + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_42_orig.ttl b/models/AOP_42_orig.ttl new file mode 100644 index 00000000..647d6d21 --- /dev/null +++ b/models/AOP_42_orig.ttl @@ -0,0 +1,177 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Inhibition of Thyroperoxidase and Subsequent Adverse Neurodevelopmental Outcomes in Mammals"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000016584 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004447 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_60311 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006590 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_30660 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005475 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010817 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007611 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0050890 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_0002421 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010468 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007420 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0045202 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007268 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#thyroid%20peroxidase + rdf:type owl:NamedIndividual , + ; + :iodide%20peroxidase%20activity ; + :iodide%20peroxidase%20activity ; + :iodide%20peroxidase%20activity ; + :iodide%20peroxidase%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#iodide%20peroxidase%20activity + rdf:type owl:NamedIndividual , + ; + :thyroid%20hormone%20generation . + +### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone + rdf:type owl:NamedIndividual , + ; + :thyroid%20hormone%20generation . + +### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20thyroxine%20level . + +### http://www.co-ode.org/ontologies/ont.owl#thyroxine + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20thyroxine%20level ; + :abnormal%20circulating%20thyroxine%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20hormone%20levels ; + :regulation%20of%20hormone%20levels . + +### http://www.co-ode.org/ontologies/ont.owl#thyroxine + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20hormone%20levels ; + :regulation%20of%20hormone%20levels ; + :regulation%20of%20hormone%20levels ; + :regulation%20of%20hormone%20levels . + +### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20hormone%20levels + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20gene%20expression ; + :regulation%20of%20gene%20expression ; + :regulation%20of%20gene%20expression ; + :regulation%20of%20gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20gene%20expression + rdf:type owl:NamedIndividual , + ; + :brain%20development . + +### http://www.co-ode.org/ontologies/ont.owl#hippocampal%20formation + rdf:type owl:NamedIndividual , + ; + :brain%20development ; + :brain%20development ; + :brain%20development ; + :brain%20development . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20development + rdf:type owl:NamedIndividual , + ; + :chemical%20synaptic%20transmission . + +### http://www.co-ode.org/ontologies/ont.owl#synapse + rdf:type owl:NamedIndividual , + ; + :chemical%20synaptic%20transmission ; + :chemical%20synaptic%20transmission ; + :chemical%20synaptic%20transmission ; + :chemical%20synaptic%20transmission . + +### http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission + rdf:type owl:NamedIndividual , + ; + :learning%20or%20memory ; + :cognition . + +### http://www.co-ode.org/ontologies/ont.owl#learning%20or%20memory + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#cognition + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_43_orig.ttl b/models/AOP_43_orig.ttl new file mode 100644 index 00000000..d18905fa --- /dev/null +++ b/models/AOP_43_orig.ttl @@ -0,0 +1,96 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Disruption of VEGFR Signaling Leading to Developmental Defects"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000002112 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0043184 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000007563 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0001525 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0003158 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_0000178 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008015 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/UBERON_0035753 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0009653 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20receptor%202 + rdf:type owl:NamedIndividual , + ; + :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; + :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; + :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; + :vascular%20endothelial%20growth%20factor%20receptor%202%20binding . + +### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20receptor%202%20binding + rdf:type owl:NamedIndividual , + ; + :angiogenesis . + +### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20receptor%201 + rdf:type owl:NamedIndividual , + ; + :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; + :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; + :vascular%20endothelial%20growth%20factor%20receptor%202%20binding ; + :vascular%20endothelial%20growth%20factor%20receptor%202%20binding . + +### http://www.co-ode.org/ontologies/ont.owl#vascular%20endothelial%20growth%20factor%20receptor%202%20binding + rdf:type owl:NamedIndividual , + ; + :angiogenesis . + +### http://www.co-ode.org/ontologies/ont.owl#angiogenesis + rdf:type owl:NamedIndividual , + ; + :endothelium%20development . + +### http://www.co-ode.org/ontologies/ont.owl#endothelium%20development + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_48_orig.ttl b/models/AOP_48_orig.ttl new file mode 100644 index 00000000..5903fafc --- /dev/null +++ b/models/AOP_48_orig.ttl @@ -0,0 +1,219 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Binding of agonists to ionotropic glutamate receptors in adult brain causes excitotoxicity that mediates neuronal cell death, contributing to learning and memory impairment."^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/GO_0005739 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007612 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007613 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008219 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0002229 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0017146 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004972 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_39124 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006816 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0099536 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008328 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0004970 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000129 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0001847 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CL_0000127 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex + rdf:type owl:NamedIndividual , + ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity + rdf:type owl:NamedIndividual , + ; + :calcium%20ion%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion + rdf:type owl:NamedIndividual , + ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport ; + :calcium%20ion%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#calcium%20ion%20transport + rdf:type owl:NamedIndividual , + ; + :mitochondrion ; + :mitochondrion ; + :mitochondrion ; + :mitochondrion . + +### http://www.co-ode.org/ontologies/ont.owl#neurodegeneration + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling ; + :synaptic%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#neurodegeneration + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling ; + :synaptic%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :neurodegeneration ; + :neurodegeneration . + +### http://www.co-ode.org/ontologies/ont.owl#astrocyte + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :neurodegeneration ; + :neurodegeneration . + +### http://www.co-ode.org/ontologies/ont.owl#NMDA%20selective%20glutamate%20receptor%20complex + rdf:type owl:NamedIndividual , + ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity ; + :NMDA%20glutamate%20receptor%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#NMDA%20glutamate%20receptor%20activity + rdf:type owl:NamedIndividual , + ; + :calcium%20ion%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#mitochondrion + rdf:type owl:NamedIndividual , + ; + :cell%20death ; + :cell%20death ; + :cell%20death ; + :cell%20death . + +### http://www.co-ode.org/ontologies/ont.owl#cell%20death + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#microglial%20cell + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :neurodegeneration ; + :neurodegeneration . + +### http://www.co-ode.org/ontologies/ont.owl#astrocyte + rdf:type owl:NamedIndividual , + ; + :brain%20inflammation ; + :brain%20inflammation . + +### http://www.co-ode.org/ontologies/ont.owl#brain%20inflammation + rdf:type owl:NamedIndividual , + ; + :neurodegeneration ; + :neurodegeneration . + +### http://www.co-ode.org/ontologies/ont.owl#learning + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#memory + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling + rdf:type owl:NamedIndividual , + ; + :learning ; + :memory . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_54_orig.ttl b/models/AOP_54_orig.ttl new file mode 100644 index 00000000..7896078a --- /dev/null +++ b/models/AOP_54_orig.ttl @@ -0,0 +1,208 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Inhibition of Na+/I- symporter (NIS) leads to learning and memory impairment "^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/CHEBI_16382 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0015705 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_30660 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010817 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000004716 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0010467 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0046903 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0045202 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007416 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007612 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0007613 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0005475 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0002882 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000015171 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0008507 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0099536 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_60311 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006590 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#sodium/iodide%20cotransporter + rdf:type owl:NamedIndividual , + ; + :sodium%3Aiodide%20symporter%20activity ; + :sodium%3Aiodide%20symporter%20activity ; + :sodium%3Aiodide%20symporter%20activity ; + :sodium%3Aiodide%20symporter%20activity . + +### http://www.co-ode.org/ontologies/ont.owl#sodium%3Aiodide%20symporter%20activity + rdf:type owl:NamedIndividual , + ; + :iodide%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#iodide + rdf:type owl:NamedIndividual , + ; + :iodide%20transport . + +### http://www.co-ode.org/ontologies/ont.owl#iodide%20transport + rdf:type owl:NamedIndividual , + ; + :thyroid%20hormone%20generation . + +### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone + rdf:type owl:NamedIndividual , + ; + :thyroid%20hormone%20generation . + +### http://www.co-ode.org/ontologies/ont.owl#thyroid%20hormone%20generation + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20thyroxine%20level . + +### http://www.co-ode.org/ontologies/ont.owl#thyroxine + rdf:type owl:NamedIndividual , + ; + :abnormal%20circulating%20thyroxine%20level ; + :abnormal%20circulating%20thyroxine%20level . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20circulating%20thyroxine%20level + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20hormone%20levels ; + :regulation%20of%20hormone%20levels . + +### http://www.co-ode.org/ontologies/ont.owl#thyroxine + rdf:type owl:NamedIndividual , + ; + :regulation%20of%20hormone%20levels ; + :regulation%20of%20hormone%20levels ; + :regulation%20of%20hormone%20levels ; + :regulation%20of%20hormone%20levels . + +### http://www.co-ode.org/ontologies/ont.owl#regulation%20of%20hormone%20levels + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :secretion . + +### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor + rdf:type owl:NamedIndividual , + ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression ; + :gene%20expression . + +### http://www.co-ode.org/ontologies/ont.owl#gene%20expression + rdf:type owl:NamedIndividual , + ; + :abnormal%20neuron%20morphology . + +### http://www.co-ode.org/ontologies/ont.owl#brain-derived%20neurotrophic%20factor + rdf:type owl:NamedIndividual , + ; + :secretion ; + :secretion ; + :secretion ; + :secretion . + +### http://www.co-ode.org/ontologies/ont.owl#secretion + rdf:type owl:NamedIndividual , + ; + :abnormal%20neuron%20morphology . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20neuron%20morphology + rdf:type owl:NamedIndividual , + ; + :synapse%20assembly ; + :synapse%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#synapse + rdf:type owl:NamedIndividual , + ; + :synapse%20assembly . + +### http://www.co-ode.org/ontologies/ont.owl#synapse%20assembly + rdf:type owl:NamedIndividual , + ; + :synaptic%20signaling . + +### http://www.co-ode.org/ontologies/ont.owl#synaptic%20signaling + rdf:type owl:NamedIndividual , + ; + :learning ; + :memory . + +### http://www.co-ode.org/ontologies/ont.owl#learning + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#memory + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . diff --git a/models/AOP_6_orig.ttl b/models/AOP_6_orig.ttl new file mode 100644 index 00000000..f37a7dcb --- /dev/null +++ b/models/AOP_6_orig.ttl @@ -0,0 +1,116 @@ +@prefix owl: . + @prefix rdf: . + @prefix xml: . + @prefix xsd: . + @prefix rdfs: . + @prefix : . + @base . + + a owl:Ontology . + "Antagonist binding to PPARĪ± leading to body-weight loss"^^xsd:string . + "review"^^xsd:string . + + +################################################################# +# Classes +################################################################# + +### http://purl.obolibrary.org/obo/PR_000013056 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0035624 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D007662 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0002118 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/CHEBI_73693 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/MP_0001263 + rdf:type owl:Class . + +### http://id.nlm.nih.gov/mesh/D009124 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0030163 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0048019 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000011048 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0003714 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/PR_000011047 + rdf:type owl:Class . + +### http://purl.obolibrary.org/obo/GO_0006635 + rdf:type owl:Class . + + + +################################################################# +# Individuals +################################################################# + +### http://www.co-ode.org/ontologies/ont.owl#peroxisome%20proliferator-activated%20receptor%20alpha + rdf:type owl:NamedIndividual , + ; + :receptor%20transactivation ; + :receptor%20transactivation ; + :receptor%20transactivation ; + :receptor%20transactivation . + +### http://www.co-ode.org/ontologies/ont.owl#receptor%20transactivation + rdf:type owl:NamedIndividual , + ; + :ketosis . + +### http://www.co-ode.org/ontologies/ont.owl#fatty%20acid%20beta-oxidation + rdf:type owl:NamedIndividual , + ; + :ketosis . + +### http://www.co-ode.org/ontologies/ont.owl#ketosis + rdf:type owl:NamedIndividual , + ; + :abnormal%20lipid%20homeostasis ; + :ketone%20body . + +### http://www.co-ode.org/ontologies/ont.owl#ketosis + rdf:type owl:NamedIndividual , + ; + :abnormal%20lipid%20homeostasis ; + :ketone%20body . + +### http://www.co-ode.org/ontologies/ont.owl#abnormal%20lipid%20homeostasis + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#ketone%20body + rdf:type owl:NamedIndividual , + . + +### http://www.co-ode.org/ontologies/ont.owl#weight%20loss + rdf:type owl:NamedIndividual , + . + + + +################################################################# +# Object Statements +################################################################# + + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty . + rdf:type owl:ObjectProperty .