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New Term Request: split/merged hemibrain neuron classes from FlyWIre #1651

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admclachlan opened this issue Jul 3, 2023 · 1 comment
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correction incorrect information in the ontology needs fixing EM terms from papers that are based on EM data new term request new terms needed VFB related to the nervous system/requested by VFB

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@admclachlan
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Tracking issue - to post tables

For new term requests, please provide the following information:

Preferred term label

Synonyms

(e.g., Absent spleen)

Textual definition

the definition should be understandable even for non-specialists. Include a PubMed ID to refer to any relevant article that provides additional information about the suggested term.

Suggested parent term

Please look in the hierarchy in a browser such as OLS

Attribution

If you would like a nanoattribution, please indicate your ORCID id

@admclachlan admclachlan added the VFB related to the nervous system/requested by VFB label Jul 3, 2023
@admclachlan admclachlan self-assigned this Jul 3, 2023
@Clare72 Clare72 self-assigned this Aug 16, 2023
@Clare72 Clare72 added new term request new terms needed correction incorrect information in the ontology needs fixing EM terms from papers that are based on EM data labels Aug 16, 2023
@Clare72
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Clare72 commented Oct 8, 2024

From Schlegel et al. (2024) - FBrf0260535:

In total, 7% of proposed hemibrain types were combined to define new ‘composite’ types (for example, SIP078,SIP080) because the hemibrain split could not be recapitulated when examining neurons from both FlyWire and the hemibrain (Fig. 3i and Extended Data Fig. 4e–g). This is not too surprising as the hemibrain philosophy was explicitly to err on the side of splitting in cases of uncertainty2. We found that 5% of proposed hemibrain types needed to be split, for example, because truncation of neurons in the hemibrain removed a key defining feature

I think we can go ahead now and merge the 'composite' types (with commas in 'hemibrain_type' in supplement 1)

I would like to see further supporting evidence (better descriptions of differences and more brains) before doing the splits - the existing hemibrain terms are good enough for now, without creating a bunch of new terms that might need to be obsoleted in future if not reproducible.

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correction incorrect information in the ontology needs fixing EM terms from papers that are based on EM data new term request new terms needed VFB related to the nervous system/requested by VFB
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