diff --git a/Formula/p/python-setuptools.rb b/Formula/p/python-setuptools.rb
index a82ce4226d7e..6b04816c9977 100644
--- a/Formula/p/python-setuptools.rb
+++ b/Formula/p/python-setuptools.rb
@@ -1,17 +1,17 @@
 class PythonSetuptools < Formula
   desc "Easily download, build, install, upgrade, and uninstall Python packages"
   homepage "https://setuptools.pypa.io/"
-  url "https://files.pythonhosted.org/packages/cd/01/e30d66bbb6403b7d41ac1ac0e3c51727c5e8f3558d8f9a9efe4282e90308/setuptools-74.1.3.tar.gz"
-  sha256 "fbb126f14b0b9ffa54c4574a50ae60673bbe8ae0b1645889d10b3b14f5891d28"
+  url "https://files.pythonhosted.org/packages/a7/17/133e1cd1e24373e1898ca3c7330f5c385b46c7091f0451e678f37245591b/setuptools-75.0.0.tar.gz"
+  sha256 "25af69c809d9334cd8e653d385277abeb5a102dca255954005a7092d282575ea"
   license "MIT"
 
   bottle do
-    sha256 cellar: :any_skip_relocation, arm64_sequoia: "30ca813a08196c60f57289045b7708b04f8d786d99f8f8c1125d8145d7b23729"
-    sha256 cellar: :any_skip_relocation, arm64_sonoma:  "30ca813a08196c60f57289045b7708b04f8d786d99f8f8c1125d8145d7b23729"
-    sha256 cellar: :any_skip_relocation, arm64_ventura: "30ca813a08196c60f57289045b7708b04f8d786d99f8f8c1125d8145d7b23729"
-    sha256 cellar: :any_skip_relocation, sonoma:        "0b85089398190084856bb38b8988f6db7b9b483b34c1ec9f3e6d98a6e921ba30"
-    sha256 cellar: :any_skip_relocation, ventura:       "0b85089398190084856bb38b8988f6db7b9b483b34c1ec9f3e6d98a6e921ba30"
-    sha256 cellar: :any_skip_relocation, x86_64_linux:  "f6b72e5abf1ad4260470950c82e6df8b6067e2ba473328a09cfab15bad0bc9af"
+    sha256 cellar: :any_skip_relocation, arm64_sequoia: "3301145d7b80c94c0e35b8328e7a3d84cedc6e1b3e9aff136865093de644ce04"
+    sha256 cellar: :any_skip_relocation, arm64_sonoma:  "3301145d7b80c94c0e35b8328e7a3d84cedc6e1b3e9aff136865093de644ce04"
+    sha256 cellar: :any_skip_relocation, arm64_ventura: "3301145d7b80c94c0e35b8328e7a3d84cedc6e1b3e9aff136865093de644ce04"
+    sha256 cellar: :any_skip_relocation, sonoma:        "41349f8c73c63e9169c59d67fcd379c60c2389034f22f8f46576c5ca681eeee6"
+    sha256 cellar: :any_skip_relocation, ventura:       "41349f8c73c63e9169c59d67fcd379c60c2389034f22f8f46576c5ca681eeee6"
+    sha256 cellar: :any_skip_relocation, x86_64_linux:  "397fb43bfe89fc25a7ceb0d9f110af50a55bf01e00e3a239b0b5839bb5a0da7d"
   end
 
   depends_on "python@3.12" => [:build, :test]