Skip to content

Commit 5bfa87a

Browse files
authored
Merge pull request #9 from Merck/feat-backhaz
Background surv statements
2 parents 36bbb5b + 9c41869 commit 5bfa87a

File tree

1 file changed

+5
-4
lines changed

1 file changed

+5
-4
lines changed

README.md

+5-4
Original file line numberDiff line numberDiff line change
@@ -54,9 +54,10 @@ Given this, the package enables:
5454
for each of the 3 model structures (given a time horizon), to evaluate
5555
plausibility and structural sensitivity. Additional functionality:
5656

57-
- Constraining the estimates to ensure that mortality hazards are at
58-
least as great as background morality.
57+
- Constraining the estimates to ensure that mortality survival is no greater than background mortality.
58+
5959
- Applying discounting to obtained discounted restricted means.
60+
6061
- Bootstrap standard errors can be derived.
6162

6263
- Graphically illustrate observed and fitted membership probabilities,
@@ -80,8 +81,7 @@ be used for the one-piece parametric and spline modeling.
8081
A second vignette, `vignette("background-mortality")` illustrates how,
8182
after fitting models, estimates of restricted mean durations in health
8283
states can be calculated after constraining for background mortality
83-
from a given life table. This mortality is assumed to add to the
84-
mortality hazard observed in the dataset.
84+
from a given life table. Projected survival in the modeled dataset is assumed to be no greater than background survival.
8585

8686
## Installation
8787

@@ -136,3 +136,4 @@ different licenses.
136136
application to prognostic modelling and estimation of treatment
137137
effects. Statistics in Medicine 21(1):2175-2197; 2002. [DOI:
138138
10.1002/sim.1203](https://doi.org/10.1002/sim.1203)
139+

0 commit comments

Comments
 (0)