diff --git a/pkgs/development/python-modules/py65/default.nix b/pkgs/development/python-modules/py65/default.nix
index 3c06f5932f001..9f73ed1eb686c 100644
--- a/pkgs/development/python-modules/py65/default.nix
+++ b/pkgs/development/python-modules/py65/default.nix
@@ -1,40 +1,42 @@
-{ lib
-, buildPythonPackage
-, pythonOlder
-, fetchFromGitHub
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  setuptools,
+  unittestCheckHook,
 }:
 
 buildPythonPackage rec {
   pname = "py65";
-  version = "1.1.0";
-  format = "setuptools";
-
-  disabled = pythonOlder "3.6";
+  version = "1.2.0";
+  pyproject = true;
 
   src = fetchFromGitHub {
     owner = "mnaberez";
     repo = "py65";
     rev = "refs/tags/${version}";
-    hash = "sha256-WLs3TAZovuphWZIvMvM3CZnqg1aZfMF4Yrqw46k+bLA=";
+    hash = "sha256-BMX+sMPx/YBFA4NFkaY0rl0EPicGHgb6xXVvLEIdllA=";
   };
 
-  postPatch = ''
-    substituteInPlace py65/tests/test_monitor.py \
-          --replace "test_argv_rom" "dont_test_argv_rom" \
-          --replace "test_argv_combination_rom_mpu" "dont_test_argv_combination_rom_mpu"
-  '';
+  build-system = [ setuptools ];
+
+  nativeCheckInputs = [ unittestCheckHook ];
 
   meta = {
-    homepage = "https://py65.readthedocs.io/";
+    homepage = "https://github.com/mnaberez/py65";
     description = "Emulate 6502-based microcomputer systems in Python";
-    mainProgram = "py65mon";
     longDescription = ''
       Py65 includes a program called Py65Mon that functions as a machine
       language monitor. This kind of program is sometimes also called a
       debugger. Py65Mon provides a command line with many convenient commands
       for interacting with the simulated 6502-based system.
     '';
+    changelog = "https://github.com/mnaberez/py65/blob/${src.rev}/CHANGES.txt";
     license = lib.licenses.bsd3;
-    maintainers = with lib.maintainers; [ AndersonTorres tomasajt ];
+    mainProgram = "py65mon";
+    maintainers = with lib.maintainers; [
+      AndersonTorres
+      tomasajt
+    ];
   };
 }