diff --git a/pkgs/development/python-modules/expiringdict/default.nix b/pkgs/development/python-modules/expiringdict/default.nix
index 772b3d6363357..e4904230a4978 100644
--- a/pkgs/development/python-modules/expiringdict/default.nix
+++ b/pkgs/development/python-modules/expiringdict/default.nix
@@ -2,17 +2,17 @@
   lib,
   buildPythonPackage,
   fetchFromGitHub,
+  fetchpatch2,
   dill,
-  coverage,
-  coveralls,
   mock,
-  nose,
+  pytestCheckHook,
+  setuptools
 }:
 
 buildPythonPackage rec {
   pname = "expiringdict";
   version = "1.2.2";
-  format = "setuptools";
+  pyproject = true;
 
   # use fetchFromGitHub instead of fetchPypi because the test suite of
   # the package is not included into the PyPI tarball
@@ -23,20 +23,28 @@ buildPythonPackage rec {
     hash = "sha256-vRhJSHIqc51I+s/wndtfANM44CKW3QS1iajqyoSBf0I=";
   };
 
+  patches = [
+    # apply mailgun/expiringdict#49 to address NixOS/nixpkgs#326513
+    (fetchpatch2 {
+      url = "https://github.com/mailgun/expiringdict/commit/1c0f82232d20f8b3b31c9269a4d0e9510c1721a6.patch";
+      hash = "sha256-IeeJVb2tOwRhEPNGqM30fNZyz3jFcnZNWC3I6K1+hSY=";
+    })
+
+    # apply mailgun/expiringdict#56 for compatibility with Python 3.12
+    (fetchpatch2 {
+      url = "https://github.com/mailgun/expiringdict/commit/976faf3664d54049e443aca054f5819db834577b.patch";
+      hash = "sha256-FNdnU6iUMyED5j8oAjhmJTR7zQeEc/Z5s64pdeT4F8w=";
+    })
+  ];
+
+  build-system = [ setuptools ];
+
   nativeCheckInputs = [
     dill
-    coverage
-    coveralls
     mock
-    nose
+    pytestCheckHook
   ];
 
-  checkPhase = ''
-    runHook preCheck
-    nosetests -v --with-coverage --cover-package=expiringdict
-    runHook postCheck
-  '';
-
   pythonImportsCheck = [ "expiringdict" ];
 
   meta = with lib; {