diff --git a/CMakeLists.txt b/CMakeLists.txt
index 2c3c0dd29..32289ae90 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -49,32 +49,36 @@ set(MMSEQS_CXX_FLAGS "-fsigned-char")
 
 # SIMD instruction sets support
 set(MMSEQS_ARCH "")
-if (HAVE_AVX2)
-    if (CMAKE_COMPILER_IS_CLANG)
-        set(MMSEQS_ARCH "${MMSEQS_ARCH} -mavx2 -mcx16")
-    else ()
-        set(MMSEQS_ARCH "${MMSEQS_ARCH} -mavx2 -mcx16 -Wa,-q")
-    endif ()
-    set(X64 1)
-elseif (HAVE_SSE4_1)
-    set(MMSEQS_ARCH "${MMSEQS_ARCH} -msse4.1 -mcx16")
-    set(X64 1)
-elseif (HAVE_SSE2)
-    set(MMSEQS_ARCH "${MMSEQS_ARCH} -msse2")
-    set(DISABLE_IPS4O 1)
-    set(X64 1)
-elseif (HAVE_POWER9)
+if (HAVE_POWER9)
     set(MMSEQS_ARCH "${MMSEQS_ARCH} -mcpu=power9 -mvsx")
     set(PPC64 1)
-elseif (HAVE_POWER8)
+elif (HAVE_POWER8)
     set(MMSEQS_ARCH "${MMSEQS_ARCH} -mcpu=power8 -mvsx")
     set(PPC64 1)
-elseif (HAVE_ARM8)
+elif (HAVE_ARM8)
     set(MMSEQS_ARCH "${MMSEQS_ARCH} -march=armv8-a+simd")
     set(ARM 1)
-elseif (HAVE_S390X)
+elif (HAVE_S390X)
     set(MMSEQS_ARCH "${MMSEQS_ARCH} -march=z14 -mzarch -mzvector")
     set(ZARCH 1)
+else
+	if (HAVE_AVX2)
+		if (CMAKE_COMPILER_IS_CLANG)
+			set(MMSEQS_ARCH "${MMSEQS_ARCH} -mavx2 -mcx16")
+		else ()
+			set(MMSEQS_ARCH "${MMSEQS_ARCH} -mavx2 -mcx16 -Wa,-q")
+		endif ()
+		set(X64 1)
+	endif ()
+	if (HAVE_SSE4_1)
+		set(MMSEQS_ARCH "${MMSEQS_ARCH} -msse4.1 -mcx16")
+		set(X64 1)
+	endif ()
+	if (HAVE_SSE2)
+		set(MMSEQS_ARCH "${MMSEQS_ARCH} -msse2")
+		set(DISABLE_IPS4O 1)
+		set(X64 1)
+	endif ()
 endif ()
 
 if (NATIVE_ARCH AND (MMSEQS_ARCH STREQUAL ""))