diff --git a/appveyor.yml b/appveyor.yml
index 117ddeb..82a1641 100644
--- a/appveyor.yml
+++ b/appveyor.yml
@@ -1,5 +1,5 @@
environment:
- app_version: '7.2.0'
+ app_version: '7.3.0'
version: '%app_version%.{build}'
diff --git a/lib/DCI b/lib/DCI
index 3129184..3320e0e 160000
--- a/lib/DCI
+++ b/lib/DCI
@@ -1 +1 @@
-Subproject commit 3129184a261a800df074a5fa0a272a6307ff6de1
+Subproject commit 3320e0e4297f4a7c0c7581399dcc7731f6893293
diff --git a/lib/DCIMatlab/DCIMatlabR2013b6_0.dll b/lib/DCIMatlab/DCIMatlabR2013b6_0.dll
deleted file mode 100644
index 22964ce..0000000
Binary files a/lib/DCIMatlab/DCIMatlabR2013b6_0.dll and /dev/null differ
diff --git a/lib/DCIMatlab/DCIMatlabR2013b6_1.dll b/lib/DCIMatlab/DCIMatlabR2013b6_1.dll
new file mode 100644
index 0000000..e980e22
Binary files /dev/null and b/lib/DCIMatlab/DCIMatlabR2013b6_1.dll differ
diff --git a/lib/DCIMatlab/ml_freadtab.dll b/lib/DCIMatlab/ml_freadtab.dll
new file mode 100644
index 0000000..8610288
Binary files /dev/null and b/lib/DCIMatlab/ml_freadtab.dll differ
diff --git a/lib/DCIMatlab/ml_fwritetab.dll b/lib/DCIMatlab/ml_fwritetab.dll
new file mode 100644
index 0000000..fcb04b5
Binary files /dev/null and b/lib/DCIMatlab/ml_fwritetab.dll differ
diff --git a/lib/Dimensions b/lib/Dimensions
index 443802d..d159e10 160000
--- a/lib/Dimensions
+++ b/lib/Dimensions
@@ -1 +1 @@
-Subproject commit 443802d74373119a0da12ac271cf4ee51d625d4d
+Subproject commit d159e10d47a3ab73242618bc8fe0d85f1e38f8a0
diff --git a/lib/Schema b/lib/Schema
index 7eaddcc..ba10b25 160000
--- a/lib/Schema
+++ b/lib/Schema
@@ -1 +1 @@
-Subproject commit 7eaddcc9b3addfde4c18cbdf392ae8972a43a7d8
+Subproject commit ba10b251d111d6370d04904da2b261acdc7279dd
diff --git a/packages.config b/packages.config
index 9657859..9a2cf00 100644
--- a/packages.config
+++ b/packages.config
@@ -1,7 +1,7 @@
-
-
-
-
+
+
+
+
diff --git a/rakefile b/rakefile
index 95ac6a3..5211be0 100644
--- a/rakefile
+++ b/rakefile
@@ -90,7 +90,7 @@ end
def copy_to_lib_dir(target_lib_dir)
copy_depdencies lib_dir, target_lib_dir do
- copy_dci_dll
+ copy_files File.join('DCI','x86'), 'dll'
copy_schema_xsd
copy_dcimatlab_dll
copy_dimensions_xml
diff --git a/scripts b/scripts
index 97d4fc3..1533da9 160000
--- a/scripts
+++ b/scripts
@@ -1 +1 @@
-Subproject commit 97d4fc353d3e75b97ea765790c1ce0c06f9a9913
+Subproject commit 1533da91c69e9d4fe53c49479f57f11bf458a438
diff --git a/src/matlab_toolbox_core b/src/matlab_toolbox_core
index 8a18f57..b69660c 160000
--- a/src/matlab_toolbox_core
+++ b/src/matlab_toolbox_core
@@ -1 +1 @@
-Subproject commit 8a18f57abeef17a1cc14aa638aeb8512d2a2ebcb
+Subproject commit b69660ce8f2169d09ddc397b6ba6723f2e2f4e9b
diff --git a/tests/checkHelptextForDirectory.m b/tests/checkHelptextForDirectory.m
index 34a57dc..17de0af 100644
--- a/tests/checkHelptextForDirectory.m
+++ b/tests/checkHelptextForDirectory.m
@@ -4,8 +4,7 @@ function checkHelptextForDirectory(functionDir)
% CHECKHELPTEXTFORDIRECTORY(functionDir)
% functionDir name of the directory
-% Open Systems Pharmacology Suite; support@systems-biology.com
-% Date: 16-Sep-2010
+% Open Systems Pharmacology Suite; http://open-systems-pharmacology.org
files=dir([functionDir filesep '*.m']);
diff --git a/tests/loop_BasisToolBox.m b/tests/loop_BasisToolBox.m
index da4535e..c8b8244 100644
--- a/tests/loop_BasisToolBox.m
+++ b/tests/loop_BasisToolBox.m
@@ -3,8 +3,7 @@
%
% LOOP_BASISTOOLBOX
-% Open Systems Pharmacology Suite; support@systems-biology.com
-% Date: 16-Sep-2010
+% Open Systems Pharmacology Suite; http://open-systems-pharmacology.org
% prepare logDir
if ~exist('log','dir')
diff --git a/tests/mergeErrorFlag.m b/tests/mergeErrorFlag.m
index 0c50641..730eb57 100644
--- a/tests/mergeErrorFlag.m
+++ b/tests/mergeErrorFlag.m
@@ -7,9 +7,7 @@
% ErrorFlag double: Maximum of ErrorFlag_tmp
% ErrorMessage (string): concatination of all
-% Open Systems Pharmacology Suite; support@systems-biology.com
-% Date: 16-Sep-2010
-
+% Open Systems Pharmacology Suite; http://open-systems-pharmacology.org
if isempty(ErrorFlag_tmp)
ErrorFlag=0;
diff --git a/tests/models/ModelTemplate.pksim5 b/tests/models/ModelTemplate.pksim5
new file mode 100644
index 0000000..082fe71
Binary files /dev/null and b/tests/models/ModelTemplate.pksim5 differ
diff --git a/tests/models/asian woman.xml b/tests/models/asian woman.xml
index 712641f..b1e40d9 100644
--- a/tests/models/asian woman.xml
+++ b/tests/models/asian woman.xml
@@ -1,25337 +1,25688 @@
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
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-
-
-
-
-
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-
-
-
-
-
-
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-
-
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-
-
-
-
-
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
-
+
-
+
-
- K_uptake-K_rec>=0 ? K_uptake-K_rec : 0
+
+ V_pls_art+V_pls_bon+V_pls_brn+V_pls_cae+V_pls_colasc+V_pls_coldesc+V_pls_colsigm+V_pls_coltrans+V_pls_duo+V_pls_fat+V_pls_tes+V_pls_hrt+V_pls_kid+V_pls_lin+V_pls_lil+V_pls_lje+V_pls_lng+V_pls_mus+V_pls_pan+V_pls_prc+V_pls_prp+V_pls_pve+V_pls_rect+V_pls_skn+V_pls_sin+V_pls_spl+V_pls_sto+V_pls_uil+V_pls_uje+V_pls_ven
-
-
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
- V_pls_art+V_pls_bon+V_pls_brn+V_pls_cae+V_pls_colasc+V_pls_coldesc+V_pls_colsigm+V_pls_coltrans+V_pls_duo+V_pls_fat+V_pls_tes+V_pls_hrt+V_pls_kid+V_pls_lin+V_pls_lil+V_pls_lje+V_pls_lng+V_pls_mus+V_pls_pan+V_pls_prc+V_pls_prp+V_pls_pve+V_pls_rect+V_pls_skn+V_pls_sin+V_pls_spl+V_pls_sto+V_pls_uil+V_pls_uje+V_pls_ven
+ K_uptake-K_rec>=0 ? K_uptake-K_rec : 0
+
+
+
+
+
+
+ P_1 + P_2 + P_3 + P_4 + P_5 + P_6 + P_7 + P_8 + P_9 + P_10 + P_11 + P_12 + P_13 + P_14 + P_15 + P_16
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ Weight_blood + Weight_tissue
+
+
+
+
+
+
+ P_1 + P_2 + P_3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- M_art + M_sto + M_sin + M_lin + M_pan + M_spl + M_liv + M_lng + M_mus + M_fat + M_skn + M_kid + M_brn + M_hrt + M_bon + M_tes + M_pve + M_ven
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
+
+
+
+
+
+
Age* 365.25/7 + GA
-
-
+
+
-
+
Height>0 ? BW / (Height)^2 : 0
-
-
+
+
+
+
+
+ 1.6667 * W^0.5 * (H*10)^ 0.5
+
+
+
-
+
0.41
-
+
51.24
-
+
15.4896
-
+
fQ_art*C_bc_art+fQ_bon*C_bc_bon+fQ_fat*C_bc_fat+fQ_mus*C_bc_mus+fQ_skn*C_bc_skn
-
-
-
-
-
-
-
-
-
-
+
+
+
+
+
+
+
+
+
+
-
+
fQ_art*C_pls_art+fQ_bon*C_pls_bon+fQ_fat*C_pls_fat+fQ_mus*C_pls_mus+fQ_skn*C_pls_skn
-
-
-
-
-
-
-
-
-
-
+
+
+
+
+
+
+
+
+
+
-
+
(fQ_art*C_pls_art+fQ_bon*C_pls_bon+fQ_fat*C_pls_fat+fQ_mus*C_pls_mus+fQ_skn*C_pls_skn)*fu
-
-
-
-
-
-
-
-
-
-
-
+
+
+
+
+
+
+
+
+
+
+
-
+
(1-HCT)*(fQ_art*C_pls_art+fQ_bon*C_pls_bon+fQ_fat*C_pls_fat+fQ_mus*C_pls_mus+fQ_skn*C_pls_skn) + HCT*(fQ_art*C_bc_art+fQ_bon*C_bc_bon+fQ_fat*C_bc_fat+fQ_mus*C_bc_mus+fQ_skn*C_bc_skn)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
Volume * Density
-
-
+
+
-
- 0.644569411280264
+
+ 0.644549336391982
-
+
Volume
-
+
-
+
(1-HCT)*V
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
fu
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
C_pls*fu
-
-
+
+
-
+
Volume
-
+
-
+
HCT*V
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_rbc/fu
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
(1 - HCT) * C_pls+HCT * C_bc
-
-
-
+
+
+
-
+
Volume * Density
-
-
+
+
-
- 0.280235711460203
+
+ 0.280224776435026
-
+
Volume
-
+
-
+
(1-HCT)*V
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
fu
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
C_pls*fu
-
-
+
+
-
+
Volume
-
+
-
+
HCT*V
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_rbc/fu
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
(1 - HCT) * C_pls+HCT * C_bc
-
-
-
+
+
+
-
+
6*EHC_HalfTime
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
- M/TotalDrugMass
+
+ TotalDrugMass>0 ? M/TotalDrugMass : 0
-
-
+
+
-
+
Volume * Density
-
-
+
+
-
+
Qspec * Weight
-
-
+
+
-
- 0.00000000000728*(BW/0.02)^0.75
+
+ f_Jiso * (1-alpha_l) * Q_lymph * (V/V_mouse)^(exp_Jiso_scale - 1)
-
+
+
+
+
+
+
-
- 0.00000068*BW/0.02
+
+ f_lymph*Q*(1-HCT)
-
+
+
+
-
+
SA_pls_int*d_endo
-
-
+
+
-
+
1 - f_int - f_vas
-
-
+
+
-
+
0.032332
-
- 7.97746557544493
+
+ 7.97749307176179
-
+
Volume
-
+
-
+
f_vas*(1-HCT)*V_org
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
fu
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_vas*HCT*V
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_rbc/fu
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_int*V
-
-
+
+
-
+
pH_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_cell*V
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_cell
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
C_int * K_water_int
-
-
+
+
-
+
C_cell * K_water_cell
-
-
+
+
-
+
(f_int*C_int+f_cell*C_cell)/(f_int+f_cell)
-
-
-
-
+
+
+
+
-
+
Volume * Density
-
-
+
+
-
- 0.00000000000032*BW/0.02
+
+ SA_pls_int*d_endo
-
+
+
-
- 1.55E-14*(BW/0.02)^0.75
+
+ f_lymph*Q*(1-HCT)
-
+
+
+
-
- SA_pls_int*d_endo
+
+ f_Jiso * (1-alpha_l) * Q_lymph * (V/V_mouse)^(exp_Jiso_scale - 1)
-
-
+
+
+
+
+
+
-
+
1 - f_int - f_vas
-
-
+
+
-
+
Qspec * Weight
-
-
+
+
-
- 1.35730748813606
+
+ 1.35728860419695
-
+
0.52156
-
+
Volume
-
+
-
+
f_vas*(1-HCT)*V_org
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
fu
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_vas*HCT*V
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_rbc/fu
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_int*V
-
-
+
+
-
+
pH_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_cell*V
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_cell
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
C_int * K_water_int
-
-
+
+
-
+
C_cell * K_water_cell
-
-
+
+
-
+
(f_int*C_int+f_cell*C_cell)/(f_int+f_cell)
-
-
-
-
+
+
+
+
-
+
Volume * Density
-
-
+
+
-
+
SA_pls_int*d_endo
-
-
+
+
-
- 0.00000000261*(BW/0.02)^0.75
+
+ f_lymph*Q*(1-HCT)
-
+
+
+
-
- 0.000000079*BW/0.02
+
+ f_Jiso * (1-alpha_l) * Q_lymph * (V/V_mouse)^(exp_Jiso_scale - 1)
-
+
+
+
+
+
+
-
+
1 - f_int - f_vas
-
-
+
+
-
+
Qspec * Weight
-
-
+
+
-
- 15.5617936282565
+
+ 15.5612579479274
-
+
0.79
-
+
0.8
-
+
0.002
-
+
+ 0.15
+
+
0.16
-
+
0.18
-
- 0.15
+
+ 0.853
-
+
0.92
-
- 0.853
+
+ 0.0016
-
+
0.002024
-
- 0.0016
-
-
+
0.135
-
+
0.00899999999999998
-
+
0.03
-
+
0.025901
-
+
Volume
-
+
-
+
f_vas*(1-HCT)*V_org
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
fu
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_vas*HCT*V
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_rbc/fu
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_int*V
-
-
+
+
-
+
pH_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_cell*V
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_cell
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
C_int * K_water_int
-
-
+
+
-
+
C_cell * K_water_cell
-
-
+
+
-
+
(f_int*C_int+f_cell*C_cell)/(f_int+f_cell)
-
-
-
-
+
+
+
+
-
+
Volume * Density
-
-
+
+
-
- 0.00000000375*(BW/0.02)^0.75
+
+ SA_pls_int*d_endo
-
+
+
-
- 0.000000075*BW/0.02
+
+ f_lymph*Q*(1-HCT)
-
+
+
+
-
- SA_pls_int*d_endo
+
+ f_Jiso * (1-alpha_l) * Q_lymph * (V/V_mouse)^(exp_Jiso_scale - 1)
-
-
+
+
+
+
+
+
-
+
1 - f_int - f_vas
-
-
+
+
-
+
Qspec * Weight
-
-
+
+
-
- 0.0114993044792707
+
+ 0.0114997710656791
-
+
0.0896799999999998
-
+
Volume
-
+
-
+
f_vas*(1-HCT)*V_org
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
fu
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_vas*HCT*V
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_rbc/fu
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_int*V
-
-
+
+
-
+
pH_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_cell*V
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_cell
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
C_int * K_water_int
-
-
+
+
-
+
C_cell * K_water_cell
-
-
+
+
-
+
(f_int*C_int+f_cell*C_cell)/(f_int+f_cell)
-
-
-
-
+
+
+
+
-
+
Volume * Density
-
-
+
+
-
- SA_pls_int*d_endo
+
+ f_Jiso * (1-alpha_l) * Q_lymph * (V/V_mouse)^(exp_Jiso_scale - 1)
-
-
+
+
+
+
+
+
-
- 0.000000198*(BW/0.02)^0.75
+
+ f_lymph*Q*(1-HCT)
-
+
+
+
-
- 0.00000081*BW/0.02
+
+ SA_pls_int*d_endo
-
+
+
-
+
1 - f_int - f_vas
-
-
+
+
-
+
Qspec * Weight
-
-
+
+
-
- 0.287486332675593
+
+ 0.287482394891315
-
+
0.898334000000001
-
+
Volume
-
+
-
+
f_vas*(1-HCT)*V_org
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
fu
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_vas*HCT*V
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_rbc/fu
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_int*V
-
-
+
+
-
+
pH_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_cell*V
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_cell
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
C_int * K_water_int
-
-
+
+
-
+
C_cell * K_water_cell
-
-
+
+
-
+
(f_int*C_int+f_cell*C_cell)/(f_int+f_cell)
-
-
-
-
+
+
+
+
-
+
Volume * Density
-
-
+
+
-
+
SA_pls_int*d_endo
-
-
+
+
-
- 0.0000000649*(BW/0.02)^0.75
+
+ f_lymph*Q*(1-HCT)
-
+
+
+
-
- 0.00000021*BW/0.02
+
+ f_Jiso * (1-alpha_l) * Q_lymph * (V/V_mouse)^(exp_Jiso_scale - 1)
-
+
+
+
+
+
+
-
+
1 - f_int - f_vas
-
-
+
+
-
- (PMA^Hill/(TM50^Hill+PMA^Hill)*(1-GFR_premat)+GFR_premat) * GFR_mat / V_kid_std
+
+ Age <= Age_onset ? 1 : 1 - Decrease_Factor*(Age-Age_onset)^Hill/(TA50^Hill+(Age-Age_onset)^Hill)
+
+
+
+
+
+
+
+
+
+ GFRspec * Weight_Kidney
+
+
+
+
+
+
+ (PMA^Hill/(TM50^Hill+PMA^Hill)*(1-GFR_premat)+GFR_premat) * GFR_mat / V_kid_std * Renal_aging_scaling_factor
-
-
-
-
-
-
+
+
+
+
+
+
+
-
+
Qspec * Weight
-
-
+
+
-
- 0.353307303441634
+
+ 0.353343737185662
-
- 15
+
+ 0
-
+
44.4
-
+
+ 30
+
+
+ 59
+
+
0.11704
-
+
+ 1.5
+
+
+ 15
+
+
2.778487
-
+
Volume
-
+
-
+
f_vas*(1-HCT)*V_org
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
fu
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_vas*HCT*V
-
-
-
+
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_rbc/fu
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_int*V
-
-
+
+
-
+
pH_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_int
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
Volume
-
+
-
+
f_cell*V
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
K_water_cell
-
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
+
V>0 ? M/V : 0
-
-
+
+
-
- M/TotalDrugMass
+
+ TotalDrugMass>0 ? M/TotalDrugMass : 0
-
-
+
+
-
+
C_int * K_water_int
-
-
+
+
-
+
C_cell * K_water_cell
-
-
+
+
-
+
(f_int*C_int+f_cell*C_cell)/(f_int+f_cell)
-