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Create workflow specs for STRUCTURE (QC sub-workflow) #4

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ngaddis opened this issue Feb 24, 2020 · 0 comments
Open

Create workflow specs for STRUCTURE (QC sub-workflow) #4

ngaddis opened this issue Feb 24, 2020 · 0 comments
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@ngaddis
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ngaddis commented Feb 24, 2020

Overview of process:

  • Allow user-specified ancestry thresholds in config
  • Remove chrX
  • Genotype call rate filter
  • Remove ambiguous variants, strand check, and flipping
  • LD pruning
  • SNP subset selection
  • Input data format processing
  • Run STRUCTURE w/1KGP3 or HapMap
  • Create STRUCTURE plots for each ancestry based on self-report
  • Save standard STRUCTURE output and recommended list of samples based on pre-defined cutoffs
@ngaddis ngaddis changed the title Create workflow specs for STRUCTURE Create workflow specs for STRUCTURE (QC sub-workflow) Feb 24, 2020
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