From b3ca741de12db03ef6ffad5c5ccbd3b65088c09f Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Wed, 4 Oct 2023 08:54:32 -0400 Subject: [PATCH 01/20] add files to define an experiment template --- .gitignore | 2 + README.md | 2 +- crcsim/experiment/Dockerfile | 18 + crcsim/experiment/README.md | 134 + crcsim/experiment/cohort.csv | 100001 ++++++++++++++++++++++++++ crcsim/experiment/deploy_to_aws.sh | 9 + crcsim/experiment/parameters.json | 125 + crcsim/experiment/prepare.py | 148 + crcsim/experiment/requirements.in | 10 + crcsim/experiment/run_iteration.sh | 27 + crcsim/experiment/simulate.py | 79 + crcsim/experiment/summarize.py | 139 + 12 files changed, 100693 insertions(+), 1 deletion(-) create mode 100644 crcsim/experiment/Dockerfile create mode 100644 crcsim/experiment/README.md create mode 100644 crcsim/experiment/cohort.csv create mode 100644 crcsim/experiment/deploy_to_aws.sh create mode 100644 crcsim/experiment/parameters.json create mode 100644 crcsim/experiment/prepare.py create mode 100644 crcsim/experiment/requirements.in create mode 100644 crcsim/experiment/run_iteration.sh create mode 100644 crcsim/experiment/simulate.py create mode 100644 crcsim/experiment/summarize.py diff --git a/.gitignore b/.gitignore index feb9a10..8b5f3f9 100644 --- a/.gitignore +++ b/.gitignore @@ -35,3 +35,5 @@ __pycache__/ # Other project-specific files .DS_Store +.vscode +output.csv \ No newline at end of file diff --git a/README.md b/README.md index a900c8e..1974916 100644 --- a/README.md +++ b/README.md @@ -25,7 +25,7 @@ Note that although a Docker setup is provided, it's designed to be used only for **TODO: since open sourcing the model, only formatting and linting tests run in CI. We need to start running unit tests too.** -Tests are run automatically as part of GitHub's continuous integration process using Docker. However, you can also run them locally with `./run_tests.sh`, or you can mimic the CI process by running them in Docker with: +Testsa are run automatically as part of GitHub's continuous integration process using Docker. However, you can also run them locally with `./run_tests.sh`, or you can mimic the CI process by running them in Docker with: ``` $ docker-compose build diff --git a/crcsim/experiment/Dockerfile b/crcsim/experiment/Dockerfile new file mode 100644 index 0000000..032f923 --- /dev/null +++ b/crcsim/experiment/Dockerfile @@ -0,0 +1,18 @@ +# Because Python 3.6 is installed on our target platform, use 3.6 for the Docker +# image. +FROM python:3.6.5-stretch + +WORKDIR /code + +# First install the package dependencies. By copying only requirements.txt into +# the image beforehand, Docker will re-run this step only when requirements.txt +# changes. +COPY ./requirements.txt ./ +RUN pip install --upgrade pip \ + && pip install -r requirements.txt + +# Copy the rest of the experiment files. +COPY ./ /code + +# Declare the directory with experiment files as a volume +VOLUME /code \ No newline at end of file diff --git a/crcsim/experiment/README.md b/crcsim/experiment/README.md new file mode 100644 index 0000000..addcd4e --- /dev/null +++ b/crcsim/experiment/README.md @@ -0,0 +1,134 @@ +# Experiment Template + +On the `experiment` branch, the files in `crcsim/experiment` provide a template for the experiment structure. New experiments can branch off this branch as a starting point. + +## Scenarios + +Experiments are structured as a set of scenarios. Each scenario is defined by a set of parameters. The scenarios that make up an experiment (and the parameters that define them) are determined by the hypothesis that the experiment intends to test. + +This experiment template includes three scenarios: +1. No screening +2. 100% screening using colonoscopy +3. 100% screening using FIT + +More complex production experiments might vary screening rates, compliance rates, costs, and other parameters. + +The scenarios are created by `prepare.py`. This script reads a set of base parameters defined in `crcsim/experiment/parameters.json`, modifies them to create the scenarios, and saves them in a directory structure that will eventually be copied to AWS. + +## Defining new experiments + +To use this code as the basis for a new experiment, you should edit the following: + +- [./prepare.py](./prepare.py) - Change the scenarios to run and the associated parameter transformations. +- [./simulate.py](./simulate.py) - Change the AWS batch objects and parameters. +- [./run_iteration.sh](./run_iteration.sh) - Change the s3 bucket name, or if the experiment is substantially different, the series of commands each run entails. +- [./summarize.py](./summarize.py) - You may want to change the derived variables that are added to the model results. +- [./parameters.json](./parameters.json) - You may want to edit the base parameter values. + +## Running the experiment on AWS + +### Test runs + +If you want to conduct a test run of the experiment, consider reducing the number of iterations in Step 3 and/or using a smaller population size in Step 5. You could also comment out some FQHCs in the `initial_compliance` dict in the `create_scenarios` function in `prepare.py`. +### 1. Setup + +1. Clone this repo to your local machine +1. Set your working directory to `./simulator/crcsim/experiment` +1. Create and activate a Python 3.6 virtual environment (NOTE: Python 3.6 is not strictly necessary for running the experiment on AWS, but we recommend it because all development of the experiment and `crcsim` package took place in 3.6. Later versions of Python are probably okay but untested.) +1. Install dependencies with `pip install -r requirements.txt` + +### 2. (Optional) Build and Push Image + +Unless you've made changes to files that will affect simulation runs, this step is not necessary, since the `crcsim` image has already been uploaded to ECR. If you've changed anything in `run_iteration.sh`, `requirements.txt`, etc., you will need to rebuild and push the image. + +Run `bash deploy_to_aws.sh` to run a series of commands which build the image locally from the Dockerfile in this repo and push it to ECR. + +### 3. Prepare the Experiment Files + +The script `prepare.py` prepares the `scenarios/` directory, the parameter files that define each scenario, and the `seeds.txt` file that defines the seeds used for multiple iterations of each scenario. + +Running this script with all default arguments will replicate the seed and number of iterations of this experiment's original run. You can vary the seed by editing the script, and you can vary the number of iterations with a command line argument, e.g. `prepare.py --n=10`. + +### 4. Upload the Experiment Files to S3 + +The subdirectories and files in `scenarios/` must be uploaded to AWS S3 for the Docker containers running Batch jobs to access them. *(Note: it would be possible to avoid this step because `scenarios/` is in the build context, but we chose to rely on S3 so the Docker image does not have to be rebuilt every time `prepare.py` is run.)* + +To upload the files to S3, run +``` +aws s3 cp ./scenarios s3://crcsim-exp-template/scenarios --recursive +``` +*(Another note: this manual step is necessary because `boto3` does not include functionality to upload a directory to S3 recursively. Future experiments could improve this workflow by writing a function to upload the directory recursively in `prepare.py`. Or submit a patch to resolve https://github.com/boto/boto3/issues/358)* + +### 5. Launch the Jobs + +The script `simulate.py` uses boto3 to launch jobs in AWS Batch. It relies on the structure of `scenarios/` generated by `prepare.py` to determine the jobs to launch and their parameters. + +By default, each run uses a population size of 100,000 as with other experiments/batches. You can us the `n_people` argument to vary this parameter. For example, launch the jobs with a population size of 1,000 with the command `python simulate.py --n_people=1000`. + +After launching, you can view job status and CloudWatch logs for individual jobs in the Batch console. + +### 6. Check for Errors + +Check the Batch console to see if any of the jobs failed. It is normal for a handful to fail due to Spot availability. Check the logs if you're concerned. If more than a few jobs failed, you may have a more serious issue. Use the CloudWatch logs to diagnose. + +If you have only a few failed jobs and the reason looks innocuous, the easiest solution is to rerun the jobs manually via the Batch console. + +### 6. Analyze the Results + +Once all jobs have completed, run `summarize.py` to analyze the combined results of the model runs. This script uses pandas and s3fs to read and write files directly from S3 without saving them to your local machine. Like `simulate.py`, `summarize.py` relies on the structure of `scenarios/` to determine the files it fetches from S3. + +This step generates `summary/` and its contents: +- `combined.csv` has one row per model run +- `summarized.xlsx` includes summary statistics for each scenario. Scenarios are separated into three sheets, one for each sensitivity test. + +## AWS Architecture + +The architecture relies on four AWS services - Batch, CloudWatch, Elastic Container Registry (ECR), and S3. The role of each service is as follows. + +- Batch: high-level interface to launch Elastic Container Service (ECS) jobs +- CloudWatch: logging service to view logs for Batch jobs +- ECR: store Docker container used to run jobs +- S3: store output files generated by jobs + +Most of the AWS architecture was built via the AWS Console. As such, there is not a script available to replicate the setup steps. This section outlines those steps. + +**Important:** all AWS resources should be tagged following CDS protocols. For this project, all resources were tagged as follows. + +- project-name: crcsim +- project-number: 0216648.001.001 +- responsible-person: apreiss@rti.org + +### S3 + +We used the S3 console to create the `crcsim-exp-template` bucket to store output files generated by simulation jobs. + +### IAM + +We used the IAM console to create the `crcsim-s3-access` IAM role. This IAM role has the `AmazonS3FullAccess` policy attached, which allows a service with this role to read and write to S3. + +### Batch + +We created the following Batch objects: + +- Compute environment: `crcsim` using the FARGATE_SPOT provisioning model +- Job queue: `crcsim` +- Job definition: `crcsim`. Executes the following command in the `crcsim:latest` image. +``` +["./run_iteration.sh","Ref::npeople","Ref::iteration","Ref::seed","Ref::scenario"] +``` +- Important job definition properties: + - The `Ref::` placeholders in the command define parameters. We vary these parameters across jobs. + - Job role ARN allows us to add the `crcsim-s3-access` IAM role which gives jobs access to S3. + - Enabling tag propagation passes the job's tags on to the underlying ECS resources. This is important to ensure costs are billed to the project. + +Note that most of these resources were named `crcsim` rather than something like `crcsim-exp-template`. We expect that we will be able to use the same objects across experiments, since their structure is not specific to this experiment. +### CloudWatch + +AWS Batch automatically sends log streams from jobs to AWS CloudWatch. Some logging info is viewable from within Batch by opening a job. However, the added detail of the complete logs may be useful, particularly for debugging. To view Batch logs in CloudWatch: +1. Navigate to the [CloudWatch console](https://console.aws.amazon.com/cloudwatch/) +1. Open `Log groups` and the `/aws/batch/job` log group +1. Find the log stream for the job of interest. + +### ECR + +Pushing the Docker image to ECR is the only step of the architecture setup that was NOT completed via the AWS Console. 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--git a/crcsim/experiment/parameters.json b/crcsim/experiment/parameters.json new file mode 100644 index 0000000..36cb1c0 --- /dev/null +++ b/crcsim/experiment/parameters.json @@ -0,0 +1,125 @@ +{ + + "max_age": 100, + + "mean_duration_polyp1_polyp2": 25.5, + "mean_duration_polyp2_polyp3": 6.25, + "mean_duration_polyp2_pre": 80, + "mean_duration_polyp3_pre": 76, + "mean_duration_pre1_pre2": 3.5, + "mean_duration_pre2_pre3": 2.5, + "mean_duration_pre3_pre4": 2.5, + "mean_duration_pre1_clin1": 18, + "mean_duration_pre2_clin2": 3.9, + "mean_duration_pre3_clin3": 2.75, + "mean_duration_pre4_clin4": 1.9, + "mean_duration_clin1_dead": 135, + "mean_duration_clin2_dead": 51, + "mean_duration_clin3_dead": 19, + "mean_duration_clin4_dead": 2.7, + + "proportion_survive_clin1": 0, + "proportion_survive_clin2": 0, + "proportion_survive_clin3": 0, + "proportion_survive_clin4": 0, + + "cost_polypectomy": 170, + "cost_polyp_pathology": 65, + + "cost_treatment_stage1_initial": 34258, + 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the experiment. + + A directory named `./scenarios` will be created. Inside this directory, one + subdirectory per scenario will be created. Within each scenario subdirectory, + a parameters input file named "params.json" will be created. + + In addition, a text file of seeds (seeds.txt) will be created in the ./scenarios + directory. This file will contain a random seed for each iteration. For example, + if num_iterations=100, seeds.txt will contain 100 seeds, one per row. + + For example, suppose `num_iterations=2`, and there are three scenarios named + "base", "intervention1", and "intervention2". Then the resulting directory + hierarchy would look like this: + + scenarios/ + base/ + params.json + intervention1/ + params.json + intervention2/ + params.json + seeds.txt (will contain 2 lines, one seed per line) + """ + + scenarios_dir = Path("./scenarios") + if scenarios_dir.exists(): + prompt = "Scenarios directory already exists. Do you want to continue? [y/n] " + if input(prompt) != "y": + print("Cancelling scenario directory preparation.") + return + + for scenario in scenarios: + scenario_dir = scenarios_dir / scenario.name + scenario_dir.mkdir(exist_ok=True, parents=True) + + scenario_params_file = scenario_dir / "params.json" + with open(scenario_params_file, mode="w") as f: + json.dump(obj=scenario.params, fp=f, indent=2) + + seeds = [rng.randint(1, 2**31 - 1) for _ in range(num_iterations)] + seeds_file = scenarios_dir / "seeds.txt" + with open(seeds_file, mode="w") as f: + for seed in seeds: + f.write(str(seed)) + f.write("\n") + + +def get_default_params() -> Dict: + with open("parameters.json") as f: + params = json.load(f) + return params + + +def transform_initial_compliance(rate) -> Callable: + def transform(params): + params["initial_compliance_rate"] = rate + + return transform + + +def transform_FIT_routine_ages(age: int) -> Callable: + def transform(params): + for p in ["routine_start", "routine_end"]: + params["tests"]["FIT"][p] = age + + return transform + + +def transform_routine_test_proportion(test: str, proportion: float) -> Callable: + def transform(params): + params["tests"][test]["proportion"] = proportion + + return transform + + +def create_scenarios() -> List: + scenarios = [] + + # No screening + # + # Start and end ages are enforced by skipping testing logic if simulation time is + # less than routine_start or greater than routine end. Setting both to -1 ensures + # that simulation time will always be greater than routine end, so no routine + # testing will ever be performed. + no_screening = Scenario(name="no_screening", params=get_default_params()).transform( + transform_FIT_routine_ages(-1) + ) + scenarios.append(no_screening) + + # 100% routine test proportions + # Default parameters are already 100% FIT, so all we need to do there is adjust + # compliance. + all_fit = Scenario(name="all_FIT", params=get_default_params()).transform( + transform_initial_compliance(1.0) + ) + scenarios.append(all_fit) + + all_colonoscopy = Scenario( + name="all_colonoscopy", params=get_default_params() + ).transform(transform_initial_compliance(1.0)) + all_colonoscopy.transform(transform_routine_test_proportion("FIT", 0.0)) + all_colonoscopy.transform(transform_routine_test_proportion("Colonoscopy", 1.0)) + scenarios.append(all_colonoscopy) + + return scenarios + + +def run(n: Optional[int] = None) -> None: + if n is None: + n = NUM_ITERATIONS + rng = random.Random(SEED) + prepare_experiment_dir(scenarios=create_scenarios(), num_iterations=n, rng=rng) + + +def main() -> None: + fire.Fire(run) + + +if __name__ == "__main__": + main() diff --git a/crcsim/experiment/requirements.in b/crcsim/experiment/requirements.in new file mode 100644 index 0000000..0594152 --- /dev/null +++ b/crcsim/experiment/requirements.in @@ -0,0 +1,10 @@ +# Clone the specific commit of the model that you want to use for the experiment +git+http://cds-mallard-web.rti.org/crcsim/crc-screening-sim@0e53795db26fa64c9e72a2f8503ef1c5392c9e72#egg=crcsim +fire +pandas +openpyxl==3.0.9 +wheel +matplotlib +s3fs==0.5.1 # fix backward compatibility issue with new version of s3fs and fsspec +fsspec==0.8.3 # fix backward compatibility issue with new version of s3fs and fsspec +aiobotocore[awscli,boto3] \ No newline at end of file diff --git a/crcsim/experiment/run_iteration.sh b/crcsim/experiment/run_iteration.sh new file mode 100644 index 0000000..e0f55a0 --- /dev/null +++ b/crcsim/experiment/run_iteration.sh @@ -0,0 +1,27 @@ +#!/usr/bin/env bash + +npeople="$1" +iteration="$2" +seed=$3 +scenario="$4" + +output_dir="./output" + +if [ ! -d "$output_dir" ]; then + echo "Creating output directory" + mkdir $output_dir +fi + +aws s3 cp "s3://crcsim-crccp-batch-08-accsis/scenarios/$scenario/params.json" "./params.json" + +crc-simulate \ + --npeople=$npeople \ + --seed=$seed \ + --params-file=./params.json \ + --cohort-file=./cohort.csv && + +crc-analyze \ + --params-file=./params.json && + +aws s3 cp ./results.csv "s3://crcsim-crccp-batch-08-accsis/scenarios/$scenario/results_$iteration.csv" +aws s3 cp ./output.csv "s3://crcsim-crccp-batch-08-accsis/scenarios/$scenario/output_$iteration.csv" \ No newline at end of file diff --git a/crcsim/experiment/simulate.py b/crcsim/experiment/simulate.py new file mode 100644 index 0000000..cd96f95 --- /dev/null +++ b/crcsim/experiment/simulate.py @@ -0,0 +1,79 @@ +from pathlib import Path + +import boto3 +import fire + + +def get_scenario_list() -> list: + """ + Search the scenarios directory for all parameter files. Add name of each + parent folder to scenario list. Assumes scenario directory has the structure + generated by prepare.py: + + scenarios/ + scenario_1/ + params.json + scenario_2/ + params.json + """ + scenarios = [] + + for results_file in Path("./scenarios").glob("*/params.json"): + scenarios.append(results_file.parent.name) + + return scenarios + + +def get_seed_list() -> list: + """ + Generate a list of integer seeds from ./scenarios/seeds.txt. Assumes seeds.txt has + one seed per line. + """ + with open(Path("./scenarios/seeds.txt")) as f: + seeds = f.read().splitlines() + return seeds + + +def run( + n_people: int = 100_000, + job_queue: str = "crcsim", + job_definition: str = "crcsim:6", + username: str = "apreiss", +): + scenarios = get_scenario_list() + seeds = get_seed_list() + + batch = boto3.client("batch") + + for scenario in scenarios: + for iteration, seed in enumerate(seeds): + iteration_name = f"{iteration:03}" + + job = batch.submit_job( + jobName=scenario + f"_{iteration_name}", + jobQueue=job_queue, + jobDefinition=job_definition, + parameters={ + "npeople": str(n_people), + "iteration": iteration_name, + "seed": seed, + "scenario": scenario, + }, + propagateTags=True, + tags={ + "project_number": "0216648.001.001", + "project_name": "crcsim", + "responsible_person": f"{username}@rti.org", + }, + ) + print( + f"Submitting iteration {iteration_name} for scenario {scenario}, Job ID {job['jobId']}" + ) + + +def main(): + fire.Fire(run) + + +if __name__ == "__main__": + main() diff --git a/crcsim/experiment/summarize.py b/crcsim/experiment/summarize.py new file mode 100644 index 0000000..4a22320 --- /dev/null +++ b/crcsim/experiment/summarize.py @@ -0,0 +1,139 @@ +from itertools import chain +from pathlib import Path + +import pandas as pd +import s3fs # noqa: F401 + + +S3_BUCKET_NAME = "crcsim-exp-template" + + +def main() -> None: + summary_dir = Path("./summary") + summary_dir.mkdir(exist_ok=True, parents=True) + + combined = combine_run_results() + combined.to_csv(summary_dir / "combined.csv", index=False) + + df = add_derived_variables(combined) + summary = summarize_results(df) + + with pd.ExcelWriter(summary_dir / "summarized.xlsx", engine="openpyxl") as writer: + summary.to_excel(writer, index=False) + + +def get_scenario_list() -> list: + """ + Search the scenarios directory for all parameter files. Add name of each + parent folder to scenario list. Assumes scenario directory has the structure + generated by prepare.py: + + scenarios/ + scenario_1/ + params.json + scenario_2/ + params.json + """ + scenarios = [] + + for results_file in Path("./scenarios").glob("*/params.json"): + scenarios.append(results_file.parent.name) + + return scenarios + + +def get_n_iterations() -> int: + """ + Gets the length of ./scenarios/seeds.txt + """ + with open(Path("./scenarios/seeds.txt")) as f: + seeds = f.read().splitlines() + return len(seeds) + + +def combine_run_results() -> pd.DataFrame: + """ + Gather the final analysis results of every run and concatenate them into a + single data frame. + """ + + scenarios = get_scenario_list() + n_iterations = get_n_iterations() + + dfs = [] + + for scenario in scenarios: + for iteration in range(n_iterations): + iteration_name = f"{iteration:03}" + + print(f"Fetching results for {scenario}, iteration {iteration_name}") + + df = pd.read_csv( + f"s3://{S3_BUCKET_NAME}/scenarios/{scenario}/results_{iteration_name}.csv" + ) + df["scenario"] = scenario + df["iteration"] = iteration_name + + dfs.append(df) + + if len(dfs) == 0: + raise RuntimeError("No simulation results files were found") + + return pd.concat(dfs, axis="index") + + +def add_derived_variables(df: pd.DataFrame) -> pd.DataFrame: + """ + Add derived variables to the data frame. + """ + + df["cost_treatment"] = ( + df["cost_treatment_initial"] + + df["cost_treatment_ongoing"] + + df["cost_treatment_terminal"] + ) + + df["discounted_cost_treatment"] = ( + df["discounted_cost_treatment_initial"] + + df["discounted_cost_treatment_ongoing"] + + df["discounted_cost_treatment_terminal"] + ) + + df["cost_total"] = ( + df["cost_routine"] + + df["cost_diagnostic"] + + df["cost_surveillance"] + + df["cost_treatment"] + ) + + df["discounted_cost_total"] = ( + df["discounted_cost_routine"] + + df["discounted_cost_diagnostic"] + + df["discounted_cost_surveillance"] + + df["discounted_cost_treatment"] + ) + + return df + + +def summarize_results(df: pd.DataFrame) -> pd.DataFrame: + """ + Compute the mean and standard deviation of every analysis variable, by + scenario. + """ + + groups = df.groupby("scenario") + means = groups.mean() + stds = groups.std() + + means.columns = [f"{c}_mean" for c in means.columns] + stds.columns = [f"{c}_std" for c in stds.columns] + + interleaved_columns = chain.from_iterable(zip(means.columns, stds.columns)) + summary = pd.concat([means, stds], axis="columns")[interleaved_columns] + + return summary.reset_index() + + +if __name__ == "__main__": + main() From 471d0d61648691099c0f725ab98b522c696de9b8 Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Wed, 4 Oct 2023 09:24:16 -0400 Subject: [PATCH 02/20] upgrade dev env to python 3.11 --- .gitignore | 3 ++- README.md | 2 +- crcsim/analysis.py | 10 ++++---- requirements.in | 6 ++--- requirements.txt | 59 ++++++++++++++-------------------------------- 5 files changed, 29 insertions(+), 51 deletions(-) diff --git a/.gitignore b/.gitignore index 8b5f3f9..54ee255 100644 --- a/.gitignore +++ b/.gitignore @@ -36,4 +36,5 @@ __pycache__/ # Other project-specific files .DS_Store .vscode -output.csv \ No newline at end of file +output.csv +results.csv \ No newline at end of file diff --git a/README.md b/README.md index 1974916..f13549c 100644 --- a/README.md +++ b/README.md @@ -14,7 +14,7 @@ See [docs/design.md](./docs/design.md) for a discussion of the package's design. To set up a Python development environment for `crcsim`: -1. Create a Python virtual environment based on Python 3.6. (Currently, support is limited to Python 3.6, because that is the version installed on the RTI Cluster, which is where we expect to deploy and run the experiments.) +1. Create a Python virtual environment based on Python 3.11. 1. Activate the virtual environment. 1. Install development dependencies with `pip install -r requirements.txt`. 1. Install `crcsim` with `pip install -e .`. The `-e` option specifies "development" mode, meaning that any changes you make to the code are recognized immediately without having to reinstall the package. diff --git a/crcsim/analysis.py b/crcsim/analysis.py index 4c24529..4a55fc4 100644 --- a/crcsim/analysis.py +++ b/crcsim/analysis.py @@ -679,7 +679,7 @@ def summarize(self): stage_counts = clinical_detections.new_state.value_counts() stage_counts.index = stage_counts.index.str.replace("CLINICAL_", "").str.lower() onset_distrib = stage_counts / len(clinical_detections) - for stage, value in onset_distrib.iteritems(): + for stage, value in onset_distrib.items(): replication_output_row[f"crc_onset_proportion_{stage}"] = value # Among all individuals who died from CRC, mean time between the onset of CRC @@ -779,7 +779,7 @@ def compute_status_arrays(self): f"Unexpected: more than one death event for person {p}" ) else: - death_age = int(death.time) + death_age = int(death.time.iloc[0]) alive = np.arange(max_age + 1) alive = np.where(alive > death_age, 0, 1) @@ -906,11 +906,11 @@ def compute_status_arrays(self): f"Unexpected: more than one clinical onset event for person {p}" ) # Clinical onset overall - clinical_detection_age = int(clinical_detection.time) + clinical_detection_age = int(clinical_detection.time.iloc[0]) clinical_onset[clinical_detection_age] = 1 # Five-year survival overall - clinical_detection_age_decimal = float(clinical_detection.time) - death_age_decimal = float(death.time) + clinical_detection_age_decimal = float(clinical_detection.time.iloc[0]) + death_age_decimal = float(death.time.iloc[0]) crc_onset_to_death = death_age_decimal - clinical_detection_age_decimal if crc_onset_to_death > 5: five_year_survival[clinical_detection_age] = 1 diff --git a/requirements.in b/requirements.in index b8eb93f..c2cf3b7 100644 --- a/requirements.in +++ b/requirements.in @@ -1,13 +1,13 @@ # Requirements needed for installing and using the package. Include # everything necessary to satisfy setup.py's install_requires section. fire -pandas +pandas==2.1.1 # Additional requirements needed for development. -black==22.8.0 +black==23.1.0 flake8==3.8.3 isort==5.2.0 -mypy==0.812 +mypy==1.4.1 pytest==5.4.3 wheel==0.34.2 pip-tools diff --git a/requirements.txt b/requirements.txt index 1bd0cf5..e6fb361 100644 --- a/requirements.txt +++ b/requirements.txt @@ -1,6 +1,6 @@ # -# This file is autogenerated by pip-compile -# To update, run: +# This file is autogenerated by pip-compile with Python 3.11 +# by the following command: # # pip-compile # @@ -8,7 +8,7 @@ appdirs==1.4.4 # via virtualenv attrs==19.3.0 # via pytest -black==22.8.0 +black==23.1.0 # via -r requirements.in cfgv==3.1.0 # via pre-commit @@ -16,10 +16,10 @@ click==8.0.4 # via # black # pip-tools -dataclasses==0.8 - # via black distlib==0.3.1 # via virtualenv +enum34==1.1.10 + # via fire filelock==3.0.12 # via virtualenv fire==0.3.1 @@ -28,37 +28,27 @@ flake8==3.8.3 # via -r requirements.in identify==1.4.25 # via pre-commit -importlib-metadata==1.7.0 - # via - # click - # flake8 - # pluggy - # pre-commit - # pytest - # virtualenv -importlib-resources==3.0.0 - # via - # pre-commit - # virtualenv isort==5.2.0 # via -r requirements.in mccabe==0.6.1 # via flake8 more-itertools==8.4.0 # via pytest -mypy-extensions==0.4.3 +mypy==1.4.1 + # via -r requirements.in +mypy-extensions==1.0.0 # via # black # mypy -mypy==0.812 - # via -r requirements.in nodeenv==1.4.0 # via pre-commit -numpy==1.19.1 +numpy==1.26.0 # via pandas -packaging==20.4 - # via pytest -pandas==1.1.0 +packaging==23.2 + # via + # black + # pytest +pandas==2.1.1 # via -r requirements.in pathspec==0.9.0 # via black @@ -76,11 +66,9 @@ pycodestyle==2.6.0 # via flake8 pyflakes==2.2.0 # via flake8 -pyparsing==2.4.7 - # via packaging pytest==5.4.3 # via -r requirements.in -python-dateutil==2.8.1 +python-dateutil==2.8.2 # via pandas pytz==2020.1 # via pandas @@ -89,33 +77,22 @@ pyyaml==5.3.1 six==1.15.0 # via # fire - # packaging # python-dateutil # virtualenv termcolor==1.1.0 # via fire toml==0.10.1 # via pre-commit -tomli==1.2.3 - # via black -typed-ast==1.4.3 - # via - # black - # mypy typing-extensions==4.1.1 - # via - # black - # mypy + # via mypy +tzdata==2023.3 + # via pandas virtualenv==20.0.28 # via pre-commit wcwidth==0.2.5 # via pytest wheel==0.34.2 # via -r requirements.in -zipp==3.1.0 - # via - # importlib-metadata - # importlib-resources # The following packages are considered to be unsafe in a requirements file: # pip From e9d8850f384c8a79b1154edaae4a4a5383b528ea Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Mon, 23 Oct 2023 14:39:48 -0400 Subject: [PATCH 03/20] finish experiment template --- crcsim/experiment/Dockerfile | 4 +- crcsim/experiment/README.md | 2 +- crcsim/experiment/deploy_to_aws.sh | 8 +- crcsim/experiment/requirements.in | 5 +- crcsim/experiment/requirements.txt | 124 +++++++++++++++++++++++++++++ crcsim/experiment/run_iteration.sh | 6 +- crcsim/experiment/simulate.py | 15 ++-- 7 files changed, 144 insertions(+), 20 deletions(-) create mode 100644 crcsim/experiment/requirements.txt mode change 100644 => 100755 crcsim/experiment/run_iteration.sh diff --git a/crcsim/experiment/Dockerfile b/crcsim/experiment/Dockerfile index 032f923..63d2abf 100644 --- a/crcsim/experiment/Dockerfile +++ b/crcsim/experiment/Dockerfile @@ -1,6 +1,4 @@ -# Because Python 3.6 is installed on our target platform, use 3.6 for the Docker -# image. -FROM python:3.6.5-stretch +FROM python:3.11.6-bullseye WORKDIR /code diff --git a/crcsim/experiment/README.md b/crcsim/experiment/README.md index addcd4e..d9b4b0e 100644 --- a/crcsim/experiment/README.md +++ b/crcsim/experiment/README.md @@ -34,7 +34,7 @@ If you want to conduct a test run of the experiment, consider reducing the numbe 1. Clone this repo to your local machine 1. Set your working directory to `./simulator/crcsim/experiment` -1. Create and activate a Python 3.6 virtual environment (NOTE: Python 3.6 is not strictly necessary for running the experiment on AWS, but we recommend it because all development of the experiment and `crcsim` package took place in 3.6. Later versions of Python are probably okay but untested.) +1. Create and activate a Python 3.11 virtual environment 1. Install dependencies with `pip install -r requirements.txt` ### 2. (Optional) Build and Push Image diff --git a/crcsim/experiment/deploy_to_aws.sh b/crcsim/experiment/deploy_to_aws.sh index 63e8465..794a8fd 100644 --- a/crcsim/experiment/deploy_to_aws.sh +++ b/crcsim/experiment/deploy_to_aws.sh @@ -1,9 +1,9 @@ #!/usr/bin/env bash -docker build --add-host=cds-mallard-web.rti.org:10.162.35.16 -t crcsim . && +docker buildx build --platform linux/amd64 -t crcsim . && -aws ecr get-login-password --region us-west-1 | docker login --username AWS --password-stdin 810875545305.dkr.ecr.us-west-1.amazonaws.com && +aws ecr get-login-password --region us-east-2 | docker login --username AWS --password-stdin 547883312134.dkr.ecr.us-east-2.amazonaws.com && -docker tag crcsim:latest 810875545305.dkr.ecr.us-west-1.amazonaws.com/crcsim:latest && +docker tag crcsim:latest 547883312134.dkr.ecr.us-east-2.amazonaws.com/crcsim:latest && -docker push 810875545305.dkr.ecr.us-west-1.amazonaws.com/crcsim:latest \ No newline at end of file +docker push 547883312134.dkr.ecr.us-east-2.amazonaws.com/crcsim:latest \ No newline at end of file diff --git a/crcsim/experiment/requirements.in b/crcsim/experiment/requirements.in index 0594152..a22c3e8 100644 --- a/crcsim/experiment/requirements.in +++ b/crcsim/experiment/requirements.in @@ -1,7 +1,8 @@ # Clone the specific commit of the model that you want to use for the experiment -git+http://cds-mallard-web.rti.org/crcsim/crc-screening-sim@0e53795db26fa64c9e72a2f8503ef1c5392c9e72#egg=crcsim +git+https://github.com/RTIInternational/crcsim.git@10211220d1f38239ac5ec885d00ca7a515449399 + fire -pandas +pandas==2.1.1 openpyxl==3.0.9 wheel matplotlib diff --git a/crcsim/experiment/requirements.txt b/crcsim/experiment/requirements.txt new file mode 100644 index 0000000..d41a399 --- /dev/null +++ b/crcsim/experiment/requirements.txt @@ -0,0 +1,124 @@ +# +# This file is autogenerated by pip-compile with Python 3.11 +# by the following command: +# +# pip-compile +# +aiobotocore[awscli,boto3]==2.6.0 + # via + # -r requirements.in + # s3fs +aiohttp==3.8.5 + # via aiobotocore +aioitertools==0.11.0 + # via aiobotocore +aiosignal==1.3.1 + # via aiohttp +async-timeout==4.0.3 + # via aiohttp +attrs==23.1.0 + # via aiohttp +awscli==1.29.17 + # via aiobotocore +boto3==1.28.17 + # via aiobotocore +botocore==1.31.17 + # via + # aiobotocore + # awscli + # boto3 + # s3transfer +charset-normalizer==3.3.0 + # via aiohttp +colorama==0.4.4 + # via awscli +contourpy==1.1.1 + # via matplotlib +crcsim @ git+https://github.com/RTIInternational/crcsim.git@10211220d1f38239ac5ec885d00ca7a515449399 + # via -r requirements.in +cycler==0.12.0 + # via matplotlib +docutils==0.16 + # via awscli +et-xmlfile==1.1.0 + # via openpyxl +fire==0.5.0 + # via + # -r requirements.in + # crcsim +fonttools==4.43.0 + # via matplotlib +frozenlist==1.4.0 + # via + # aiohttp + # aiosignal +fsspec==0.8.3 + # via + # -r requirements.in + # s3fs +idna==3.4 + # via yarl +jmespath==1.0.1 + # via + # boto3 + # botocore +kiwisolver==1.4.5 + # via matplotlib +matplotlib==3.8.0 + # via -r requirements.in +multidict==6.0.4 + # via + # aiohttp + # yarl +numpy==1.26.0 + # via + # contourpy + # matplotlib + # pandas +openpyxl==3.0.9 + # via -r requirements.in +packaging==23.2 + # via matplotlib +pandas==2.1.1 + # via + # -r requirements.in + # crcsim +pillow==10.0.1 + # via matplotlib +pyasn1==0.5.0 + # via rsa +pyparsing==3.1.1 + # via matplotlib +python-dateutil==2.8.2 + # via + # botocore + # matplotlib + # pandas +pytz==2023.3.post1 + # via pandas +pyyaml==6.0.1 + # via awscli +rsa==4.7.2 + # via awscli +s3fs==0.5.1 + # via -r requirements.in +s3transfer==0.6.2 + # via + # awscli + # boto3 +six==1.16.0 + # via + # fire + # python-dateutil +termcolor==2.3.0 + # via fire +tzdata==2023.3 + # via pandas +urllib3==1.26.17 + # via botocore +wheel==0.41.2 + # via -r requirements.in +wrapt==1.15.0 + # via aiobotocore +yarl==1.9.2 + # via aiohttp diff --git a/crcsim/experiment/run_iteration.sh b/crcsim/experiment/run_iteration.sh old mode 100644 new mode 100755 index e0f55a0..7bec78d --- a/crcsim/experiment/run_iteration.sh +++ b/crcsim/experiment/run_iteration.sh @@ -12,7 +12,7 @@ if [ ! -d "$output_dir" ]; then mkdir $output_dir fi -aws s3 cp "s3://crcsim-crccp-batch-08-accsis/scenarios/$scenario/params.json" "./params.json" +aws s3 cp "s3://crcsim-exp-template/scenarios/$scenario/params.json" "./params.json" crc-simulate \ --npeople=$npeople \ @@ -23,5 +23,5 @@ crc-simulate \ crc-analyze \ --params-file=./params.json && -aws s3 cp ./results.csv "s3://crcsim-crccp-batch-08-accsis/scenarios/$scenario/results_$iteration.csv" -aws s3 cp ./output.csv "s3://crcsim-crccp-batch-08-accsis/scenarios/$scenario/output_$iteration.csv" \ No newline at end of file +aws s3 cp ./results.csv "s3://crcsim-exp-template/scenarios/$scenario/results_$iteration.csv" +aws s3 cp ./output.csv "s3://crcsim-exp-template/scenarios/$scenario/output_$iteration.csv" \ No newline at end of file diff --git a/crcsim/experiment/simulate.py b/crcsim/experiment/simulate.py index cd96f95..d9054bd 100644 --- a/crcsim/experiment/simulate.py +++ b/crcsim/experiment/simulate.py @@ -37,7 +37,7 @@ def get_seed_list() -> list: def run( n_people: int = 100_000, job_queue: str = "crcsim", - job_definition: str = "crcsim:6", + job_definition: str = "crcsim:3", username: str = "apreiss", ): scenarios = get_scenario_list() @@ -59,12 +59,12 @@ def run( "seed": seed, "scenario": scenario, }, - propagateTags=True, - tags={ - "project_number": "0216648.001.001", - "project_name": "crcsim", - "responsible_person": f"{username}@rti.org", - }, + # propagateTags=True, + # tags={ + # "project_number": "0216648.001.001", + # "project_name": "crcsim", + # "responsible_person": f"{username}@rti.org", + # }, ) print( f"Submitting iteration {iteration_name} for scenario {scenario}, Job ID {job['jobId']}" @@ -76,4 +76,5 @@ def main(): if __name__ == "__main__": + test = "" main() From f417d15116c8efcc3a95b662cf03bcfd8c18227b Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Thu, 30 Nov 2023 10:48:36 -0500 Subject: [PATCH 04/20] fix bugs identified in the first experiment --- crcsim/experiment/requirements.in | 4 ++-- crcsim/experiment/requirements.txt | 10 ++++++---- crcsim/experiment/simulate.py | 7 ------- crcsim/experiment/summarize.py | 7 ++++--- 4 files changed, 12 insertions(+), 16 deletions(-) diff --git a/crcsim/experiment/requirements.in b/crcsim/experiment/requirements.in index a22c3e8..91b29cc 100644 --- a/crcsim/experiment/requirements.in +++ b/crcsim/experiment/requirements.in @@ -6,6 +6,6 @@ pandas==2.1.1 openpyxl==3.0.9 wheel matplotlib -s3fs==0.5.1 # fix backward compatibility issue with new version of s3fs and fsspec -fsspec==0.8.3 # fix backward compatibility issue with new version of s3fs and fsspec +s3fs==2023.10.0 +fsspec==2023.10.0 aiobotocore[awscli,boto3] \ No newline at end of file diff --git a/crcsim/experiment/requirements.txt b/crcsim/experiment/requirements.txt index d41a399..1db0a6a 100644 --- a/crcsim/experiment/requirements.txt +++ b/crcsim/experiment/requirements.txt @@ -4,12 +4,14 @@ # # pip-compile # -aiobotocore[awscli,boto3]==2.6.0 +aiobotocore[awscli,boto3]==2.7.0 # via # -r requirements.in # s3fs aiohttp==3.8.5 - # via aiobotocore + # via + # aiobotocore + # s3fs aioitertools==0.11.0 # via aiobotocore aiosignal==1.3.1 @@ -52,7 +54,7 @@ frozenlist==1.4.0 # via # aiohttp # aiosignal -fsspec==0.8.3 +fsspec==2023.10.0 # via # -r requirements.in # s3fs @@ -100,7 +102,7 @@ pyyaml==6.0.1 # via awscli rsa==4.7.2 # via awscli -s3fs==0.5.1 +s3fs==2023.10.0 # via -r requirements.in s3transfer==0.6.2 # via diff --git a/crcsim/experiment/simulate.py b/crcsim/experiment/simulate.py index d9054bd..899381f 100644 --- a/crcsim/experiment/simulate.py +++ b/crcsim/experiment/simulate.py @@ -38,7 +38,6 @@ def run( n_people: int = 100_000, job_queue: str = "crcsim", job_definition: str = "crcsim:3", - username: str = "apreiss", ): scenarios = get_scenario_list() seeds = get_seed_list() @@ -59,12 +58,6 @@ def run( "seed": seed, "scenario": scenario, }, - # propagateTags=True, - # tags={ - # "project_number": "0216648.001.001", - # "project_name": "crcsim", - # "responsible_person": f"{username}@rti.org", - # }, ) print( f"Submitting iteration {iteration_name} for scenario {scenario}, Job ID {job['jobId']}" diff --git a/crcsim/experiment/summarize.py b/crcsim/experiment/summarize.py index 4a22320..7fd560c 100644 --- a/crcsim/experiment/summarize.py +++ b/crcsim/experiment/summarize.py @@ -72,14 +72,16 @@ def combine_run_results() -> pd.DataFrame: f"s3://{S3_BUCKET_NAME}/scenarios/{scenario}/results_{iteration_name}.csv" ) df["scenario"] = scenario - df["iteration"] = iteration_name + df["iteration"] = iteration dfs.append(df) if len(dfs) == 0: raise RuntimeError("No simulation results files were found") - return pd.concat(dfs, axis="index") + return pd.concat( + dfs, axis="index" + ).copy() # copy to address pandas fragmentation warning def add_derived_variables(df: pd.DataFrame) -> pd.DataFrame: @@ -121,7 +123,6 @@ def summarize_results(df: pd.DataFrame) -> pd.DataFrame: Compute the mean and standard deviation of every analysis variable, by scenario. """ - groups = df.groupby("scenario") means = groups.mean() stds = groups.std() From 724dffd79ff1a5c69f0bc52c16178ad28a88e18e Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Thu, 30 Nov 2023 12:06:10 -0500 Subject: [PATCH 05/20] update S3 bucket path and readme --- crcsim/experiment/README.md | 18 ++++++++---------- crcsim/experiment/run_iteration.sh | 6 +++--- crcsim/experiment/summarize.py | 2 +- 3 files changed, 12 insertions(+), 14 deletions(-) diff --git a/crcsim/experiment/README.md b/crcsim/experiment/README.md index d9b4b0e..85a2687 100644 --- a/crcsim/experiment/README.md +++ b/crcsim/experiment/README.md @@ -1,17 +1,15 @@ -# Experiment Template +# Replication of the CRCCP intervention scenarios -On the `experiment` branch, the files in `crcsim/experiment` provide a template for the experiment structure. New experiments can branch off this branch as a starting point. +This experiment is a replication of the CRCCP compliance intervention experiment, which was conducted prior to open-sourcing the model and making some changes to the AWS infrastructure. We are replicating this experiment to ensure continuity after those changes. -## Scenarios +The CRCCP compliance intervention experiment examines the cost-effectiveness of interventions designed to improve compliance with routine screening. -Experiments are structured as a set of scenarios. Each scenario is defined by a set of parameters. The scenarios that make up an experiment (and the parameters that define them) are determined by the hypothesis that the experiment intends to test. +The experiment is designed around 8 health centers (labeled FHQC1-FHQC8), each having its own baseline compliance rate, intervention cost, and post-intervention compliance rate. -This experiment template includes three scenarios: -1. No screening -2. 100% screening using colonoscopy -3. 100% screening using FIT +We don't model the intervention explicitly. In other words, we didn't add any code to the model to implement the intervention. Instead, we model the intervention by assuming it leads to a change in the compliance rate, and so we run a pair of simulations: one using the baseline compliance rate and another using the post-intervention compliance rate. Any differences in outcomes can therefore be attributed to the intervention. +## Scenarios -More complex production experiments might vary screening rates, compliance rates, costs, and other parameters. +Includes 2 scenarios per health center: one baseline scenario and one intervention scenario. The baseline scenarios are based on real data and the intervention scenarios include a hypothetical increase in screening compliance rates. The scenarios are created by `prepare.py`. This script reads a set of base parameters defined in `crcsim/experiment/parameters.json`, modifies them to create the scenarios, and saves them in a directory structure that will eventually be copied to AWS. @@ -55,7 +53,7 @@ The subdirectories and files in `scenarios/` must be uploaded to AWS S3 for the To upload the files to S3, run ``` -aws s3 cp ./scenarios s3://crcsim-exp-template/scenarios --recursive +aws s3 cp ./scenarios s3://crcsim-exp-crccp-replication/scenarios --recursive ``` *(Another note: this manual step is necessary because `boto3` does not include functionality to upload a directory to S3 recursively. Future experiments could improve this workflow by writing a function to upload the directory recursively in `prepare.py`. Or submit a patch to resolve https://github.com/boto/boto3/issues/358)* diff --git a/crcsim/experiment/run_iteration.sh b/crcsim/experiment/run_iteration.sh index 7bec78d..89e0710 100755 --- a/crcsim/experiment/run_iteration.sh +++ b/crcsim/experiment/run_iteration.sh @@ -12,7 +12,7 @@ if [ ! -d "$output_dir" ]; then mkdir $output_dir fi -aws s3 cp "s3://crcsim-exp-template/scenarios/$scenario/params.json" "./params.json" +aws s3 cp "s3://crcsim-exp-crccp-replication/scenarios/$scenario/params.json" "./params.json" crc-simulate \ --npeople=$npeople \ @@ -23,5 +23,5 @@ crc-simulate \ crc-analyze \ --params-file=./params.json && -aws s3 cp ./results.csv "s3://crcsim-exp-template/scenarios/$scenario/results_$iteration.csv" -aws s3 cp ./output.csv "s3://crcsim-exp-template/scenarios/$scenario/output_$iteration.csv" \ No newline at end of file +aws s3 cp ./results.csv "s3://crcsim-exp-crccp-replication/scenarios/$scenario/results_$iteration.csv" +aws s3 cp ./output.csv "s3://crcsim-exp-crccp-replication/scenarios/$scenario/output_$iteration.csv" \ No newline at end of file diff --git a/crcsim/experiment/summarize.py b/crcsim/experiment/summarize.py index 7fd560c..156c03b 100644 --- a/crcsim/experiment/summarize.py +++ b/crcsim/experiment/summarize.py @@ -5,7 +5,7 @@ import s3fs # noqa: F401 -S3_BUCKET_NAME = "crcsim-exp-template" +S3_BUCKET_NAME = "crcsim-exp-crccp-replication" def main() -> None: From cbea79dfdab3d79bea4829c5d56ae0b0b261d8df Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Thu, 30 Nov 2023 12:09:27 -0500 Subject: [PATCH 06/20] update prepare script for fqhc intervention scenarios --- crcsim/experiment/prepare.py | 63 +++++++++++++----------------------- 1 file changed, 23 insertions(+), 40 deletions(-) diff --git a/crcsim/experiment/prepare.py b/crcsim/experiment/prepare.py index 1a28f0b..dcd0600 100644 --- a/crcsim/experiment/prepare.py +++ b/crcsim/experiment/prepare.py @@ -86,49 +86,32 @@ def transform(params): return transform -def transform_FIT_routine_ages(age: int) -> Callable: - def transform(params): - for p in ["routine_start", "routine_end"]: - params["tests"]["FIT"][p] = age - - return transform - - -def transform_routine_test_proportion(test: str, proportion: float) -> Callable: - def transform(params): - params["tests"][test]["proportion"] = proportion - - return transform - - def create_scenarios() -> List: + # For each health center, define the initial compliance rate in the baseline + # scenario and the implementation scenario. + initial_compliance = { + "fqhc1": (0.522, 0.593), + "fqhc2": (0.154, 0.421), + "fqhc3": (0.519, 0.615), + "fqhc4": (0.278, 0.374), + "fqhc5": (0.383, 0.572), + "fqhc6": (0.211, 0.392), + "fqhc7": (0.257, 0.354), + "fqhc8": (0.190, 0.390), + } + scenarios = [] - # No screening - # - # Start and end ages are enforced by skipping testing logic if simulation time is - # less than routine_start or greater than routine end. Setting both to -1 ensures - # that simulation time will always be greater than routine end, so no routine - # testing will ever be performed. - no_screening = Scenario(name="no_screening", params=get_default_params()).transform( - transform_FIT_routine_ages(-1) - ) - scenarios.append(no_screening) - - # 100% routine test proportions - # Default parameters are already 100% FIT, so all we need to do there is adjust - # compliance. - all_fit = Scenario(name="all_FIT", params=get_default_params()).transform( - transform_initial_compliance(1.0) - ) - scenarios.append(all_fit) - - all_colonoscopy = Scenario( - name="all_colonoscopy", params=get_default_params() - ).transform(transform_initial_compliance(1.0)) - all_colonoscopy.transform(transform_routine_test_proportion("FIT", 0.0)) - all_colonoscopy.transform(transform_routine_test_proportion("Colonoscopy", 1.0)) - scenarios.append(all_colonoscopy) + for fqhc, rates in initial_compliance.items(): + baseline = Scenario( + name=f"{fqhc}_baseline", params=get_default_params() + ).transform(transform_initial_compliance(rates[0])) + scenarios.append(baseline) + + implementation = Scenario( + name=f"{fqhc}_implementation", params=get_default_params() + ).transform(transform_initial_compliance(rates[1])) + scenarios.append(implementation) return scenarios From 845b688a8fe2b4bac5cb47e995683feb6f2310f7 Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Thu, 21 Dec 2023 09:35:42 -0500 Subject: [PATCH 07/20] start updating prepare script with sensitivity 2 and placeholders for sensitivities 1 and 3 --- crcsim/experiment/prepare.py | 40 ++++++++++++++++++++++++++++++++++++ 1 file changed, 40 insertions(+) diff --git a/crcsim/experiment/prepare.py b/crcsim/experiment/prepare.py index dcd0600..2d93c43 100644 --- a/crcsim/experiment/prepare.py +++ b/crcsim/experiment/prepare.py @@ -2,6 +2,7 @@ import random from pathlib import Path from typing import Callable, Dict, List, Optional +from copy import copy import fire @@ -86,6 +87,18 @@ def transform(params): return transform +def transform_treatment_cost(stage: str, phase: str, value: int) -> Callable: + def transform(params): + params[f"cost_treatment_stage{stage}_{phase}"] = value + + return transform + + +# TODO: add transform function to handle lowered repeat compliance + +# TODO: add transform function to handle lowered diagnostic compliance + + def create_scenarios() -> List: # For each health center, define the initial compliance rate in the baseline # scenario and the implementation scenario. @@ -99,6 +112,8 @@ def create_scenarios() -> List: "fqhc7": (0.257, 0.354), "fqhc8": (0.190, 0.390), } + low_initial_stage_3_treatment_cost = 67_300 + low_initial_stage_4_treatment_cost = 97_931 scenarios = [] @@ -113,6 +128,31 @@ def create_scenarios() -> List: ).transform(transform_initial_compliance(rates[1])) scenarios.append(implementation) + # TODO: Sensitivity Analysis 1. Lower repeat compliance (note that the baseline runs stay the same) + ... + + # Sensitivity analysis 2. Lower cost for stage III and stage IV initial phase + baseline_low_cost = copy(baseline) + baseline_low_cost.transform( + transform_treatment_cost("3", "initial", low_initial_stage_3_treatment_cost) + ).transform( + transform_treatment_cost("4", "initial", low_initial_stage_4_treatment_cost) + ) + baseline_low_cost.name = f"{fqhc}_baseline_low_initial_treat_cost" + scenarios.append(baseline_low_cost) + + implementation_low_cost = copy(implementation) + implementation_low_cost.transform( + transform_treatment_cost("3", "initial", low_initial_stage_3_treatment_cost) + ).transform( + transform_treatment_cost("4", "initial", low_initial_stage_4_treatment_cost) + ) + implementation_low_cost.name = f"{fqhc}_implementation_low_initial_treat_cost" + scenarios.append(implementation_low_cost) + + # TODO: Sensitivity analysis 3. Lower ccompliance with diagnostic colonoscopy + ... + return scenarios From a4d6e810b6e1a28dfe481cb7bed3d2c937ef1d22 Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Fri, 22 Dec 2023 10:50:06 -0500 Subject: [PATCH 08/20] update requirements to use crcsim commit that includes 100% diagnostic compliance when symptomatic --- crcsim/experiment/requirements.in | 2 +- crcsim/experiment/requirements.txt | 2 +- 2 files changed, 2 insertions(+), 2 deletions(-) diff --git a/crcsim/experiment/requirements.in b/crcsim/experiment/requirements.in index 91b29cc..53f0b59 100644 --- a/crcsim/experiment/requirements.in +++ b/crcsim/experiment/requirements.in @@ -1,5 +1,5 @@ # Clone the specific commit of the model that you want to use for the experiment -git+https://github.com/RTIInternational/crcsim.git@10211220d1f38239ac5ec885d00ca7a515449399 +git+https://github.com/RTIInternational/crcsim.git@f25bb2d2e84729d64df8f30b58ad00d224e1c4c3 fire pandas==2.1.1 diff --git a/crcsim/experiment/requirements.txt b/crcsim/experiment/requirements.txt index 1db0a6a..8223995 100644 --- a/crcsim/experiment/requirements.txt +++ b/crcsim/experiment/requirements.txt @@ -36,7 +36,7 @@ colorama==0.4.4 # via awscli contourpy==1.1.1 # via matplotlib -crcsim @ git+https://github.com/RTIInternational/crcsim.git@10211220d1f38239ac5ec885d00ca7a515449399 +crcsim @ git+https://github.com/RTIInternational/crcsim.git@f25bb2d2e84729d64df8f30b58ad00d224e1c4c3 # via -r requirements.in cycler==0.12.0 # via matplotlib From 4336fa11b5670ce90a90402a5df31856b049d4ee Mon Sep 17 00:00:00 2001 From: Praveen Zirali Date: Tue, 2 Jan 2024 11:13:01 -0500 Subject: [PATCH 09/20] Sensitivity Scenarios 1 and 3 --- crcsim/experiment/prepare.py | 39 +- .../experiment/scenarios/all_FIT/params.json | 1214 +++++++++++++ .../scenarios/all_FIT_IRR/params.json | 1214 +++++++++++++ .../scenarios/all_FIT_start_45/params.json | 1214 +++++++++++++ .../all_FIT_start_45_IRR/params.json | 1214 +++++++++++++ .../scenarios/all_colonoscopy/params.json | 1214 +++++++++++++ .../scenarios/all_colonoscopy_IRR/params.json | 1214 +++++++++++++ .../all_colonoscopy_start_45/params.json | 1214 +++++++++++++ .../all_colonoscopy_start_45_IRR/params.json | 1214 +++++++++++++ .../scenarios/fqhc1_baseline/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../fqhc1_implementation/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1215 +++++++++++++ .../params.json | 1214 +++++++++++++ .../scenarios/fqhc2_baseline/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../fqhc2_implementation/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1215 +++++++++++++ .../params.json | 1214 +++++++++++++ .../scenarios/fqhc3_baseline/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../fqhc3_implementation/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1215 +++++++++++++ .../params.json | 1214 +++++++++++++ .../scenarios/fqhc4_baseline/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../fqhc4_implementation/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1215 +++++++++++++ .../params.json | 1214 +++++++++++++ .../scenarios/fqhc5_baseline/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../fqhc5_implementation/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1215 +++++++++++++ .../params.json | 1214 +++++++++++++ .../scenarios/fqhc6_baseline/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../fqhc6_implementation/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1215 +++++++++++++ .../params.json | 1214 +++++++++++++ .../scenarios/fqhc7_baseline/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../fqhc7_implementation/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1215 +++++++++++++ .../params.json | 1214 +++++++++++++ .../scenarios/fqhc8_baseline/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../fqhc8_implementation/params.json | 1214 +++++++++++++ .../params.json | 1214 +++++++++++++ .../params.json | 1215 +++++++++++++ .../params.json | 1214 +++++++++++++ .../scenarios/no_screening/params.json | 1214 +++++++++++++ .../scenarios/no_screening_IRR/params.json | 1214 +++++++++++++ crcsim/experiment/scenarios/seeds.txt | 10 + crcsim/experiment/summary/combined.csv | 1601 +++++++++++++++++ crcsim/experiment/summary/summarized.xlsx | Bin 0 -> 89499 bytes 78 files changed, 91490 insertions(+), 4 deletions(-) create mode 100644 crcsim/experiment/scenarios/all_FIT/params.json create mode 100644 crcsim/experiment/scenarios/all_FIT_IRR/params.json create mode 100644 crcsim/experiment/scenarios/all_FIT_start_45/params.json create mode 100644 crcsim/experiment/scenarios/all_FIT_start_45_IRR/params.json create mode 100644 crcsim/experiment/scenarios/all_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/all_colonoscopy_IRR/params.json create mode 100644 crcsim/experiment/scenarios/all_colonoscopy_start_45/params.json create mode 100644 crcsim/experiment/scenarios/all_colonoscopy_start_45_IRR/params.json create mode 100644 crcsim/experiment/scenarios/fqhc1_baseline/params.json create mode 100644 crcsim/experiment/scenarios/fqhc1_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc1_baseline_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc1_implementation/params.json create mode 100644 crcsim/experiment/scenarios/fqhc1_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc1_implementation_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc2_baseline/params.json create mode 100644 crcsim/experiment/scenarios/fqhc2_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc2_baseline_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc2_implementation/params.json create mode 100644 crcsim/experiment/scenarios/fqhc2_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc3_baseline/params.json create mode 100644 crcsim/experiment/scenarios/fqhc3_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc3_baseline_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc3_implementation/params.json create mode 100644 crcsim/experiment/scenarios/fqhc3_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc3_implementation_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc4_baseline/params.json create mode 100644 crcsim/experiment/scenarios/fqhc4_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc4_baseline_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc4_implementation/params.json create mode 100644 crcsim/experiment/scenarios/fqhc4_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc4_implementation_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc5_baseline/params.json create mode 100644 crcsim/experiment/scenarios/fqhc5_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc5_baseline_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc5_implementation/params.json create mode 100644 crcsim/experiment/scenarios/fqhc5_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc5_implementation_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc6_baseline/params.json create mode 100644 crcsim/experiment/scenarios/fqhc6_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc6_baseline_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc6_baseline_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc6_implementation/params.json create mode 100644 crcsim/experiment/scenarios/fqhc6_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc6_implementation_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc7_baseline/params.json create mode 100644 crcsim/experiment/scenarios/fqhc7_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc7_baseline_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc7_implementation/params.json create mode 100644 crcsim/experiment/scenarios/fqhc7_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc7_implementation_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc8_baseline/params.json create mode 100644 crcsim/experiment/scenarios/fqhc8_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc8_baseline_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/fqhc8_implementation/params.json create mode 100644 crcsim/experiment/scenarios/fqhc8_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json create mode 100644 crcsim/experiment/scenarios/fqhc8_implementation_Lower_repeat_compliance/params.json create mode 100644 crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json create mode 100644 crcsim/experiment/scenarios/no_screening/params.json create mode 100644 crcsim/experiment/scenarios/no_screening_IRR/params.json create mode 100644 crcsim/experiment/scenarios/seeds.txt create mode 100644 crcsim/experiment/summary/combined.csv create mode 100644 crcsim/experiment/summary/summarized.xlsx diff --git a/crcsim/experiment/prepare.py b/crcsim/experiment/prepare.py index 2d93c43..1effe36 100644 --- a/crcsim/experiment/prepare.py +++ b/crcsim/experiment/prepare.py @@ -95,9 +95,19 @@ def transform(params): # TODO: add transform function to handle lowered repeat compliance +def transform_repeat_Compliance(rate) -> Callable: + def transform(params): + params["lowered_repeat_compliance"] = rate + + return transform # TODO: add transform function to handle lowered diagnostic compliance +def transform_Compliance_with_diagnostic_colonoscopy(rate) -> Callable: + def transform(params): + params["diagnostic_compliance_rate"] = rate + + return transform def create_scenarios() -> List: # For each health center, define the initial compliance rate in the baseline @@ -114,7 +124,8 @@ def create_scenarios() -> List: } low_initial_stage_3_treatment_cost = 67_300 low_initial_stage_4_treatment_cost = 97_931 - + diagnostic_compliance_rate= 1.0 + lower_repeat_compliance=0.0 scenarios = [] for fqhc, rates in initial_compliance.items(): @@ -129,7 +140,15 @@ def create_scenarios() -> List: scenarios.append(implementation) # TODO: Sensitivity Analysis 1. Lower repeat compliance (note that the baseline runs stay the same) - ... + baseline_lower_repeat_compliance = copy(baseline) + baseline_lower_repeat_compliance.name = f"{fqhc}_baseline_Lower_repeat_compliance" + scenarios.append(baseline_lower_repeat_compliance) + implementation_lower_repeat_compliance = copy(implementation) + implementation_lower_repeat_compliance.transform( + transform_repeat_Compliance(lower_repeat_compliance) + ) + implementation_lower_repeat_compliance.name = f"{fqhc}_implementation_Lower_repeat_compliance" + scenarios.append(implementation_lower_repeat_compliance) # Sensitivity analysis 2. Lower cost for stage III and stage IV initial phase baseline_low_cost = copy(baseline) @@ -150,8 +169,20 @@ def create_scenarios() -> List: implementation_low_cost.name = f"{fqhc}_implementation_low_initial_treat_cost" scenarios.append(implementation_low_cost) - # TODO: Sensitivity analysis 3. Lower ccompliance with diagnostic colonoscopy - ... + # TODO: Sensitivity analysis 3. Lower compliance with diagnostic colonoscopy + baseline_lower_compliance = copy(baseline) + baseline_lower_compliance.transform( + transform_Compliance_with_diagnostic_colonoscopy(diagnostic_compliance_rate) + ) + baseline_lower_compliance.name = f"{fqhc}_baseline_Lower_compliance_with_diagnostic_colonoscopy" + scenarios.append(baseline_lower_compliance) + + implementation_lower_compliance = copy(implementation) + implementation_lower_compliance.transform( + transform_Compliance_with_diagnostic_colonoscopy(diagnostic_compliance_rate) + ) + implementation_lower_compliance.name = f"{fqhc}_implementation_Lower_compliance_with_diagnostic_colonoscopy" + scenarios.append(implementation_lower_compliance) return scenarios diff --git a/crcsim/experiment/scenarios/all_FIT/params.json b/crcsim/experiment/scenarios/all_FIT/params.json new file mode 100644 index 0000000..ee83598 --- /dev/null +++ b/crcsim/experiment/scenarios/all_FIT/params.json @@ -0,0 +1,1214 @@ +{ + "max_age": 100, + 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+} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/all_colonoscopy_start_45/params.json b/crcsim/experiment/scenarios/all_colonoscopy_start_45/params.json new file mode 100644 index 0000000..338791f --- /dev/null +++ b/crcsim/experiment/scenarios/all_colonoscopy_start_45/params.json @@ -0,0 +1,1214 @@ +{ + "max_age": 100, + "mean_duration_polyp1_polyp2": 25.5, + "mean_duration_polyp2_polyp3": 6.25, + "mean_duration_polyp2_pre": 80, + "mean_duration_polyp3_pre": 76, + "mean_duration_pre1_pre2": 3.5, + "mean_duration_pre2_pre3": 2.5, + "mean_duration_pre3_pre4": 2.5, + "mean_duration_pre1_clin1": 18, + "mean_duration_pre2_clin2": 3.9, + "mean_duration_pre3_clin3": 2.75, + "mean_duration_pre4_clin4": 1.9, + "mean_duration_clin1_dead": 135, + "mean_duration_clin2_dead": 51, + "mean_duration_clin3_dead": 19, + "mean_duration_clin4_dead": 2.7, + "proportion_survive_clin1": 0, + "proportion_survive_clin2": 0, + "proportion_survive_clin3": 0, + "proportion_survive_clin4": 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a/crcsim/experiment/scenarios/seeds.txt b/crcsim/experiment/scenarios/seeds.txt new file mode 100644 index 0000000..2d292ea --- /dev/null +++ b/crcsim/experiment/scenarios/seeds.txt @@ -0,0 +1,10 @@ +1001608934 +1865687462 +519221856 +196202418 +1876440239 +481309692 +257361246 +893058778 +1708949663 +859680834 diff --git a/crcsim/experiment/summary/combined.csv b/crcsim/experiment/summary/combined.csv new file mode 100644 index 0000000..3e1df7a --- /dev/null +++ b/crcsim/experiment/summary/combined.csv @@ -0,0 +1,1601 @@ 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10:00:28 -0500 Subject: [PATCH 10/20] Delete crcsim/experiment/scenarios directory --- .../experiment/scenarios/all_FIT/params.json | 1214 ---------------- .../scenarios/all_FIT_IRR/params.json | 1214 ---------------- .../scenarios/all_FIT_start_45/params.json | 1214 ---------------- .../all_FIT_start_45_IRR/params.json | 1214 ---------------- .../scenarios/all_colonoscopy/params.json | 1214 ---------------- .../scenarios/all_colonoscopy_IRR/params.json | 1214 ---------------- .../all_colonoscopy_start_45/params.json | 1214 ---------------- .../all_colonoscopy_start_45_IRR/params.json | 1214 ---------------- .../scenarios/fqhc1_baseline/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../fqhc1_implementation/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1215 ----------------- .../params.json | 1214 ---------------- .../scenarios/fqhc2_baseline/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../fqhc2_implementation/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1215 ----------------- .../params.json | 1214 ---------------- .../scenarios/fqhc3_baseline/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../fqhc3_implementation/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1215 ----------------- .../params.json | 1214 ---------------- .../scenarios/fqhc4_baseline/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../fqhc4_implementation/params.json | 1214 ---------------- .../params.json | 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1214 ---------------- .../fqhc7_implementation/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1215 ----------------- .../params.json | 1214 ---------------- .../scenarios/fqhc8_baseline/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../fqhc8_implementation/params.json | 1214 ---------------- .../params.json | 1214 ---------------- .../params.json | 1215 ----------------- .../params.json | 1214 ---------------- .../scenarios/no_screening/params.json | 1214 ---------------- .../scenarios/no_screening_IRR/params.json | 1214 ---------------- crcsim/experiment/scenarios/seeds.txt | 10 - 75 files changed, 89854 deletions(-) delete mode 100644 crcsim/experiment/scenarios/all_FIT/params.json delete mode 100644 crcsim/experiment/scenarios/all_FIT_IRR/params.json delete mode 100644 crcsim/experiment/scenarios/all_FIT_start_45/params.json 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a/crcsim/experiment/scenarios/all_FIT_start_45/params.json b/crcsim/experiment/scenarios/all_FIT_start_45/params.json deleted file mode 100644 index e7fb5ed..0000000 --- a/crcsim/experiment/scenarios/all_FIT_start_45/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - 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-} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/all_colonoscopy_start_45_IRR/params.json b/crcsim/experiment/scenarios/all_colonoscopy_start_45_IRR/params.json deleted file mode 100644 index a06fedc..0000000 --- a/crcsim/experiment/scenarios/all_colonoscopy_start_45_IRR/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - 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b/crcsim/experiment/scenarios/fqhc1_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json deleted file mode 100644 index 4eb030b..0000000 --- a/crcsim/experiment/scenarios/fqhc1_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - 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b/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json deleted file mode 100644 index 4eb030b..0000000 --- a/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - 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20c819f..0000000 --- a/crcsim/experiment/scenarios/fqhc1_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - 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-} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc2_implementation/params.json b/crcsim/experiment/scenarios/fqhc2_implementation/params.json deleted file mode 100644 index de6a9e4..0000000 --- a/crcsim/experiment/scenarios/fqhc2_implementation/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - 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a/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json deleted file mode 100644 index 2244d73..0000000 --- a/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json +++ /dev/null @@ -1,1215 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - 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a/crcsim/experiment/scenarios/fqhc4_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc4_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json deleted file mode 100644 index cb19cb9..0000000 --- a/crcsim/experiment/scenarios/fqhc4_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 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a/crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json deleted file mode 100644 index cb19cb9..0000000 --- a/crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 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b/crcsim/experiment/scenarios/fqhc4_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json deleted file mode 100644 index 2477fd6..0000000 --- a/crcsim/experiment/scenarios/fqhc4_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - 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a/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json deleted file mode 100644 index 2477fd6..0000000 --- a/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - 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deleted file mode 100644 index 0423bd7..0000000 --- a/crcsim/experiment/scenarios/fqhc5_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 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a/crcsim/experiment/scenarios/fqhc7_baseline_Lower_repeat_compliance/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - "cost_treatment_stage1_terminal": 68339, - 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0.00028 - ] -} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc7_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc7_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json deleted file mode 100644 index 8c46304..0000000 --- a/crcsim/experiment/scenarios/fqhc7_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - 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a/crcsim/experiment/scenarios/fqhc8_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc8_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json deleted file mode 100644 index bec085c..0000000 --- a/crcsim/experiment/scenarios/fqhc8_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 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a/crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json deleted file mode 100644 index bec085c..0000000 --- a/crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 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b/crcsim/experiment/scenarios/fqhc8_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json deleted file mode 100644 index a5a6747..0000000 --- a/crcsim/experiment/scenarios/fqhc8_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - 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a/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json deleted file mode 100644 index a5a6747..0000000 --- a/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - 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crcsim/experiment/summary/combined.csv delete mode 100644 crcsim/experiment/summary/summarized.xlsx diff --git a/crcsim/experiment/summary/combined.csv b/crcsim/experiment/summary/combined.csv deleted file mode 100644 index 3e1df7a..0000000 --- a/crcsim/experiment/summary/combined.csv +++ /dev/null @@ -1,1601 +0,0 @@ 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-100000,95780,43790,413.8651075381081,6335,64.93004802672792,4902,50.553351430361246,1953,19.97285445813322,77.36330519993753,79.69793059021613,66.21135634370845,68.06226379677624,77.12242123963387,79.4608268488482,66.10755760692,67.96328885068532,0.2408839603036625,237.10374136793175,0.1037987367884483,98.9749460909195,117.18102,87.19299526061486,122343.93401545208,91034.65782064613,237.33781,167.7807881382446,247316.51701816663,174694.86128444836,256.71322,141.59901621353265,265343.35978283564,145652.2566207582,3269.93568,1733.554864690643,3371063.6562956776,1766990.9737843417,895.03408,463.2966872585583,918845.145124243,468085.70396592014,1712.78419,830.7610853188833,1752631.8960116934,834893.5616434711,0.38002,100000,0,532641,5561.087909793277,0,0.0,0,0.0,28197,293.725203591564,0,0.0,32441,335.08039256629775,1361120,0,59746,0,0,0,0,0,64,0.668197953643767,0,0.0,0,0.0,0,0.0,0.06335,0.16670175253934,0.3082872928176796,0.01953,0.3390752493200362,0.6609247506799637,24.337738148041723,4.38574766715463,0.3215014279885761,0.2356181150550795,0.2168502651978784,0.2260301917584659,11.47726966871184,6.017154476841672,20.78970855467272,12417.533831265811,55.959476638588654,14.004196718601008,18.066481232049323,12.385599516278695,11.503199171659636,0.5783353733170135,0.7974025974025974,0.7106598984771574,0.5974729241877257,0.1241768579492003,0.7472766884531591,0.9295454545454546,0.875,0.7389558232931727,0.1594827586206896,0.512340425531915,0.7160839160839161,0.64375,0.5564610011641443,0.1143200962695547,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022787810040815,0.0048058400081111,0.0069216092233995,0.0088382299158844,0.0111452337855152,0.0130305097168918,0.0152309103884188,0.0175048227572902,0.0198266699370452,0.0219722864686738,0.0241052761038002,0.0262344887045951,0.0280899454035102,0.0299947486022014,0.0321609076843733,0.0339942757359399,0.0360691368246739,0.0381544841886988,0.040371928730975,0.0423997001936249,0.057238565331274,0.0707921102721245,0.0843301498107708,0.0975181591699866,0.1098451712180777,0.1247251585623678,0.1402604564350555,0.1542906397650364,0.1678857057435426,0.1806837551860547,0.1962336068221461,0.2063143549364021,0.2158636284571229,0.2252416779668431,0.2337456530351719,0.2428554015269882,0.2518021737674917,0.2605747824327059,0.2675763969237051,0.2751955294467919,0.2823436885568226,0.288681253142797,0.2947218934911242,0.3011902336118136,0.3074008864064113,0.3118639891585561,0.3163238479161711,0.3213808208014465,0.3246080082933782,0.3281640093523374,0.3276560795982389,0.3269466184339023,0.3253129228687415,0.325189273536381,0.3242235101798187,0.3229596988891949,0.3220473063839886,0.3230660787174401,0.3240797650754626,0.3248359954363947,0.3263059352181239,0.3267316957586288,0.32735275623559,0.3273837482386096,0.3286356749476924,0.3293765456202004,0.3307508939213349,0.3347642174526085,0.3386108094854461,0.339127673929436,0.3429484253765404,0.3448750529436679,0.3492739108662994,0.3502058240585455,0.3503160675535428,0.3519226176259852,0.3559975331483194,0.3547928513403737,0.3586380128384036,0.3565351894818252,0.0,2.377991984447664,60.24758477808752,184.314693266051,260.1055003410715,fqhc7_implementation,90 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-100000,95667,44578,421.9636865376776,6082,62.33079327249731,4776,49.2646367085829,1860,18.992965181305987,77.3345703778802,79.74098912213049,66.17493331886145,68.08307214095639,77.10118775409477,79.51086564792065,66.07379256037308,67.98631742983711,0.233382623785431,230.12347420983303,0.1011407584883699,96.75471111927436,127.62926,94.9947702674048,133409.9114637231,99297.3232853594,256.59846,182.62331119072832,267712.33549708885,190386.665402624,271.31136,150.09571802521808,280661.24159846135,154393.38275212338,3190.85052,1697.0842862841391,3294788.8613628526,1733366.182993235,886.74271,455.44133635343104,912832.0319441396,461995.9300003461,1628.73642,795.7876226281943,1665426.887014331,798462.9729365208,0.38024,100000,0,580133,6064.086884714688,0,0.0,0,0.0,30555,318.68878505649803,0,0.0,34274,354.38552478911225,1289785,0,56485,0,0,0,0,0,56,0.5749108888122341,0,0.0,0,0.0,0,0.0,0.06082,0.1599516095097833,0.3058204537980927,0.0186,0.3341213553979511,0.6658786446020488,24.37256076535963,4.324847552449599,0.3251675041876047,0.2340871021775544,0.2116834170854271,0.2290619765494137,11.567270318490207,6.192446340325435,19.827831641017266,12254.579108787888,54.67978078927104,13.652144600550828,17.767592410639914,12.240275146914014,11.019768631166276,0.586892797319933,0.7960644007155635,0.7160334835801674,0.5959780621572212,0.1473788328387734,0.7426099495313626,0.920704845814978,0.8471910112359551,0.7323420074349443,0.1735159817351598,0.5231631749778696,0.7108433734939759,0.6633574007220217,0.5515151515151515,0.1401515151515151,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024521228087952,0.0047466428658363,0.0069234361358698,0.0093005763307955,0.0116939423546653,0.0140735984999031,0.0159901222473928,0.0183586526771758,0.0207144172343951,0.0226052933464437,0.0246476706258846,0.0266544778495639,0.0284370916797843,0.0304610374889223,0.0327479584146354,0.0346065138022691,0.0366153112923112,0.0387070656743374,0.0410534308269972,0.043082600175124,0.0580117423371847,0.072349960212757,0.0855814246425797,0.0980744949494949,0.1100890332925439,0.1250661361664303,0.140372855444199,0.1546901297428577,0.167773322641005,0.1807759194452197,0.1952198110358514,0.2046057691266153,0.2139226591495336,0.2232330530740935,0.2307624533309838,0.2402694527848255,0.2491211231766793,0.2576239918107472,0.2650159436242524,0.2720690998235847,0.279199740806739,0.2854234432405869,0.2913712912884481,0.297193419382648,0.3020209989682588,0.3061958677787771,0.3114288218135383,0.316005855024502,0.3194320287094977,0.3224682625564148,0.3217689822294022,0.3200715120676614,0.3196530003936786,0.3192091210852937,0.3183375606283095,0.3160011622750003,0.3139397192794101,0.3148739619674708,0.314524235454468,0.3154216437867712,0.3154349859681946,0.3157853212094913,0.3163599908101673,0.3173392223783711,0.3167746580273578,0.3164925411923697,0.3166283133043552,0.3204641681041242,0.323895413870246,0.3269886588944404,0.3295910916392844,0.3319157984265362,0.3351551702475185,0.3329794494577993,0.3355158544570199,0.3380678483390069,0.3412172341066586,0.3402473075388911,0.3430578065910318,0.3524933384088313,0.0,2.486625877484613,60.86705629742786,173.37023099184697,253.94923582920123,fqhc8_implementation,23 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-100000,95722,44398,420.2482188002758,6012,61.55324794718038,4754,49.14230793339045,1884,19.3163536073212,77.35013418219063,79.72239055415832,66.19198520499623,68.07174685041124,77.10792609897803,79.48015415063172,66.08741816472764,67.96986745603246,0.2422080832126028,242.23640352660425,0.1045670402685914,101.87939437878411,128.22326,95.33284673417695,133953.57389105952,99593.22489519331,255.17072,181.227427232918,266135.91441883787,188887.953900794,262.75985,144.4313952106102,272355.7280457993,149119.03539137705,3193.79308,1687.3941784662834,3301176.29176156,1727474.681833105,890.37412,457.41815181677714,920009.4649087985,467726.4749251539,1663.07091,816.2457649788755,1705785.5769833478,824620.7990245866,0.37887,100000,0,582833,6088.798813229979,0,0.0,0,0.0,30365,316.6147803012892,0,0.0,33253,344.4558199786883,1291512,0,56575,0,0,0,0,0,56,0.5850274753975053,0,0.0,1,0.0104469192035268,0,0.0,0.06012,0.1586823976561881,0.313373253493014,0.01884,0.3318074191002367,0.6681925808997632,24.366182297769797,4.354799256479784,0.3169962137147665,0.2341186369373159,0.2267564156499789,0.2221287336979386,11.358718323209375,5.829555080554475,20.234153715974045,12241.730995248232,54.09436268879474,13.49818321558151,16.98635021859614,11.75851779304434,11.851311461572744,0.571729070256626,0.793351302785265,0.7040477770404777,0.6221590909090909,0.1085343228200371,0.7265745007680492,0.9237875288683602,0.8727735368956743,0.7061224489795919,0.1298701298701298,0.5133256083429896,0.7102941176470589,0.644524236983842,0.5967940813810111,0.1027154663518299,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022287960449001,0.004573990121804,0.0068626654755136,0.0091369217009512,0.0112340113764716,0.0135075942017174,0.0157668223631876,0.0180102915951972,0.0201705242496115,0.0223384760286243,0.0246265519751478,0.0268657636100356,0.0287786063255335,0.0306758580893793,0.0324495040716696,0.0345187635686963,0.0367512248681907,0.0388351529743866,0.0405565608036438,0.0425689335361914,0.0571428571428571,0.0706343056980713,0.0835363036996598,0.0972586161536437,0.1091160512593155,0.1246969135475673,0.1398262790154395,0.1533912932301988,0.1668715854297413,0.1788443375976646,0.1929035805543875,0.2026565834949457,0.2124761852920363,0.2211922559180502,0.2298378663966274,0.2391528410413272,0.2485820195614309,0.2572232539816534,0.2645096882515769,0.2712355433413489,0.2785264010178706,0.2853099415204678,0.29181507295081,0.2975863927651674,0.3029048665315189,0.3073287215972034,0.3122540015743899,0.3168959516278597,0.3203573460205823,0.3240420874976926,0.3225576356270944,0.3209973320130924,0.3194968199470929,0.317761599352863,0.3172327827983796,0.3148688492033181,0.3128009979315027,0.3139121458882899,0.3140635391620197,0.3146185497230188,0.3157983318996147,0.3167327142603655,0.3186587639013969,0.3190598768886402,0.3212013112225221,0.3218993212966117,0.3245674147678602,0.3281679027931197,0.3309722662719808,0.3329482531968291,0.3377941645045291,0.3396036988110964,0.3431863727454909,0.3438282376147485,0.3444641358082268,0.3463351402309687,0.3442698000915611,0.3438309746860674,0.3492324561403508,0.347542242703533,0.0,1.978711458109763,57.50371153089041,176.61420374797285,258.4479165660896,fqhc8_implementation,25 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-100000,95749,44898,425.0801574951175,6208,63.52024564225214,4892,50.61149463701971,1951,20.06287271929733,77.34480713189683,79.70303624920945,66.19703327670871,68.06539599453643,77.0964078496049,79.45328382828964,66.088246599476,67.95854839480234,0.2483992822919276,249.7524209198048,0.1087866772327146,106.8475997340954,128.77898,95.83478202275468,134496.1931717303,100089.3607481589,258.19812,183.04769234453585,269295.88820770977,190808.9821768748,268.52063,147.99763670951873,278356.1290457342,152846.09826261594,3315.19579,1758.2012266072022,3428293.8516329154,1802445.9204920272,890.73153,460.0690623679876,918828.8232775276,469149.8629645152,1722.63031,854.7991450862012,1771351.335261987,866563.9729498687,0.38261,100000,0,585359,6113.463325987739,0,0.0,0,0.0,30761,320.7448641761272,0,0.0,33874,351.04283073452467,1285106,0,56350,0,0,0,0,0,50,0.5117546919550073,0,0.0,1,0.0104439733052042,0,0.0,0.06208,0.1622539923159353,0.3142719072164948,0.01951,0.3385705483672211,0.6614294516327788,24.604391161157384,4.448409647281917,0.3190923957481603,0.2330335241210139,0.2287408013082583,0.2191332788225674,11.032520440686351,5.574345040664883,21.02868179067441,12356.967538424473,55.64185003482304,13.611092729845994,17.495055769431378,12.089640737479543,12.446060798066132,0.5486508585445625,0.7868421052631579,0.6777706598334401,0.5764925373134329,0.099195710455764,0.7023633677991138,0.9191176470588236,0.8663239074550129,0.7491289198606271,0.0888888888888888,0.4898247597512719,0.7131147540983607,0.6151877133105802,0.513375796178344,0.1024734982332155,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024102974388057,0.0049671055966102,0.0070924144648727,0.0094081788163576,0.0116780598958333,0.0137284855891638,0.0160713011023525,0.0183489048858937,0.0203693478127492,0.022465697317223,0.0245285534101047,0.0265654843810971,0.0285358780823889,0.0304522002409812,0.0324789850961786,0.0347250204052113,0.0367889860773251,0.0390009127873205,0.0410950361686206,0.0430325947685865,0.0578268222913578,0.0720370021556685,0.0854388890636963,0.0988621545450721,0.1102043398494338,0.1258976447072012,0.1404605263157894,0.1544653123802223,0.1676427212687285,0.1804418502344445,0.1953700909600379,0.2046586675907476,0.2144481809178665,0.2238053029556919,0.2317745895773004,0.2415922825303542,0.2509211907367292,0.2597810309324752,0.2679477429826453,0.274753609901444,0.2813913405591736,0.2881472903580493,0.2939666086874208,0.2993356358229002,0.3045273988411219,0.3089320699385142,0.3139369074125034,0.3190658508973886,0.3228703619704254,0.3266069846475278,0.3256591362484499,0.3248643586989451,0.3235945233294321,0.3216995447647951,0.3204633204633205,0.3178358677508767,0.3165883971348607,0.3174283043927394,0.3179886322904398,0.3185593099515255,0.3200710811821923,0.3208503421483366,0.3212468859254297,0.3225531914893617,0.3249084425597532,0.3247133958017065,0.3253565316600114,0.3286752903408554,0.3318807984256396,0.3348049158811598,0.3377374823454371,0.3421907449810959,0.3436646554461733,0.3445100897721169,0.3472550316545403,0.3520152635344622,0.3539701855795558,0.3573002203084318,0.3545232273838631,0.3612467142320691,0.0,1.8177986652981688,59.812932657684605,181.20316777410488,264.5714965730502,fqhc8_implementation,35 -100000,95647,44620,423.6306418392631,6121,62.751576107980384,4830,49.902244712327615,1863,19.132853095235603,77.26811230720266,79.67858157071171,66.14032678499974,68.05053168941042,77.02403805389632,79.43509742975452,66.03379970829388,67.94713690757125,0.2440742533063371,243.48414095719303,0.1065270767058592,103.39478183917096,128.24108,95.39269454459247,134077.47237236923,99734.120824064,252.97354,179.65510751395684,264049.8813344904,187394.64647501416,266.61495,147.01815248030252,276348.86614321417,151704.08030140758,3205.1441,1697.6620073552815,3314650.684287013,1738561.4262394854,873.8193,449.0766173570932,902650.9561198992,458578.8066308647,1638.08026,807.590213409545,1683562.2235930031,817291.5552481532,0.38182,100000,0,582914,6094.430562380419,0,0.0,0,0.0,30064,313.7160600959779,0,0.0,33719,349.2634374313883,1287558,0,56535,0,0,0,0,0,57,0.5959413259171745,0,0.0,0,0.0,0,0.0,0.06121,0.1603111413755172,0.3043620323476556,0.01863,0.325,0.675,24.345055383002013,4.351136184053043,0.3238095238095238,0.2349896480331263,0.2149068322981366,0.2262939958592132,11.273779709853573,5.8739880393681325,20.081116223760645,12315.545236426316,54.97694173218976,13.592741930489314,17.752974776873774,12.209081781492475,11.42214324333419,0.5594202898550724,0.7823788546255507,0.6764705882352942,0.5827996340347666,0.1146435452793834,0.7292143401983219,0.938095238095238,0.8029556650246306,0.7391304347826086,0.1531100478468899,0.4961636828644501,0.6909090909090909,0.6321243523316062,0.5299877600979193,0.1049457177322074,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024621807017721,0.0046952165579904,0.0066903553299492,0.0089438165704528,0.0111424297619895,0.0134488028527763,0.0154847396768402,0.0176311354001736,0.0198915933728778,0.0220993343573988,0.0241421040756466,0.0264106752134118,0.0283078062478784,0.0303486072193835,0.0323729128397762,0.034410025228504,0.0362193466842099,0.0380266040851081,0.039929236692856,0.0421944887554346,0.0572584100575823,0.0717017108254497,0.0848541487283953,0.0978416508738681,0.1105937750749609,0.1258513128488661,0.1406587099996811,0.1552764569162206,0.16807028432621,0.1808054657370903,0.1959965919263165,0.2055677766820905,0.2146965900424882,0.2238176600731637,0.2319830740071406,0.2404505604261458,0.2495302223614156,0.2585370804763623,0.2660767498464548,0.2726343944072641,0.2804364715841228,0.2870102319475862,0.2927251595151687,0.2982371871847831,0.3030413669721421,0.3077388523233845,0.3122696155871511,0.3174989798000408,0.3219978194278594,0.3257057398853876,0.3251762417956405,0.3230113518807156,0.3213203051196368,0.3208837606096097,0.3194002320530747,0.3170174254509755,0.3151499769998255,0.3167504848305558,0.3177578076949361,0.319071907547439,0.3199542788614687,0.3211548743539476,0.3222937684837553,0.3235399578683161,0.3242774148446351,0.3229128452387191,0.3243822311098414,0.3284057240118515,0.3316254912970241,0.3357051995547782,0.3388335314014078,0.3411274823830877,0.344161600810537,0.3480437461491066,0.3479168643826516,0.3544409863538424,0.3589823146137139,0.3534552845528455,0.3564221434415053,0.354705661792276,0.0,2.315339627805188,57.50705251174412,181.9329864231276,261.9445224285988,fqhc8_implementation,36 -100000,95817,44600,420.8543369130739,6016,61.59658515712243,4768,49.124894329816215,1898,19.38069444879301,77.40037147260112,79.68485318246734,66.25357880581787,68.05840308032444,77.1611039672328,79.44925878604963,66.14902283163613,67.95854557721978,0.2392675053683177,235.59439641771007,0.1045559741817356,99.85750310465846,128.7077,95.73527063045714,134326.58087813226,99914.70264197078,253.7589,180.45915131246065,264362.06518676225,187862.33268883463,265.0495,146.65191007476574,273773.23439473164,150620.5946270312,3224.95902,1713.0748761350446,3326189.4548984,1748302.290966158,898.60175,463.3385469745437,926116.785121638,471851.6724323899,1668.69836,819.973586913708,1706563.125541397,822888.1462927456,0.38087,100000,0,585035,6105.75367627874,0,0.0,0,0.0,30184,314.3596647776491,0,0.0,33421,344.9909723744221,1289578,0,56629,0,0,0,0,0,70,0.7305592953233769,0,0.0,0,0.0,0,0.0,0.06016,0.1579541575865781,0.3154920212765957,0.01898,0.3429614346929059,0.6570385653070941,24.24889373006293,4.4136120238330685,0.3166946308724832,0.2348993288590604,0.2260906040268456,0.2223154362416107,11.21762100774546,5.733289065605526,20.345860810588107,12274.444513635028,54.35139024351111,13.52479788507156,17.132428095702405,11.900823968486122,11.793340294251012,0.5635486577181208,0.7955357142857142,0.6973509933774834,0.5735849056603773,0.1252319109461966,0.7396449704142012,0.9205607476635514,0.8723897911832946,0.7644787644787645,0.1367521367521367,0.4938524590163934,0.7182080924855492,0.6274328081556997,0.5118601747815231,0.1220379146919431,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0021449023158874,0.0044957472660996,0.0067703160156487,0.0092117277061986,0.0115296316612827,0.0137691181256101,0.0158039978412064,0.0180904112662268,0.0203494011578635,0.0225130354769451,0.0248756218905472,0.0268430226596944,0.029242648266798,0.0314399432291506,0.0336636519087743,0.035461066102482,0.0375452383414331,0.039568568941937,0.0415247549426815,0.0435529370127098,0.0579743402524251,0.0724866452712238,0.0863337245368429,0.0996195960572497,0.1117585080602676,0.1262915460519365,0.1402831948448363,0.1541299424816866,0.1679664579177024,0.1812728947537542,0.1956271576524741,0.2045744427870376,0.21322179368787,0.2215994143420635,0.2297636063771302,0.2388637973786751,0.2468794270862382,0.2560077366828972,0.2633364728844909,0.270346739367003,0.2768924533324075,0.2835031645939843,0.289935506774747,0.2961706311145214,0.3013953375306901,0.3065982458953705,0.3111177899666892,0.3158323676603548,0.3196261197609448,0.3236789624522894,0.3232255196475961,0.3212894523131134,0.3196550363564624,0.3181785316616777,0.3170199177150326,0.3153353019477042,0.3137174362944122,0.3147459321284022,0.3153248527277384,0.3166607270135424,0.3178471313773126,0.3185524471382598,0.3194089289457137,0.3211479483333706,0.3233814075554378,0.3244977824158622,0.3247052793439262,0.3302660092333783,0.3341781063005983,0.3367696226715491,0.3405363424551144,0.3425526245670131,0.3447183321715987,0.3501719526175009,0.3525538519424325,0.3581345674617301,0.3610603290676417,0.3645957785742732,0.3637846655791191,0.3722409277964834,0.0,2.4705820537494394,59.08104931487965,173.7735738769543,256.73298247428863,fqhc8_implementation,37 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-100000,95664,44162,416.95935775213246,6059,62.21776216758655,4739,49.05711657467804,1918,19.673022244522496,77.3097914074473,79.72208024451564,66.14907365731523,68.061163317623,77.06501811796316,79.47858752516898,66.04255153482264,67.95793210003438,0.2447732894841436,243.49271934666208,0.106522122492592,103.23121758861475,127.75334,95.00407906512322,133543.79913028935,99310.16794731896,254.1433,180.0684425116564,265303.8760662318,187871.55305199075,262.15083,144.49366285625868,272389.0178123432,149602.7180947555,3184.4949,1691.898523277401,3295583.667837431,1735334.9047472414,873.0726,454.8788162791184,902521.0110386352,465372.46642322897,1683.89901,832.9886421629047,1727770.8542398396,840990.558812681,0.37897,100000,0,580697,6070.172687740424,0,0.0,0,0.0,30124,314.381585549423,0,0.0,33109,343.8179461448403,1292558,0,56609,0,0,0,0,0,69,0.7212744606121425,0,0.0,0,0.0,0,0.0,0.06059,0.1598807293453307,0.3165538867799967,0.01918,0.3300787401574803,0.6699212598425197,24.85824167791952,4.330846151510477,0.3327706267144967,0.2253640008440599,0.2243089259337413,0.217556446507702,11.031012954542756,5.83981563607154,20.58469374269864,12238.414259261224,53.86069990945547,12.761036457227108,17.981424263907254,11.345052907220786,11.773186281100326,0.5615108672715763,0.7855805243445693,0.7051363348129359,0.562560620756547,0.1222953904045155,0.7317629179331308,0.9316455696202532,0.8735362997658079,0.7605042016806722,0.16015625,0.4960560911481156,0.6998514115898959,0.6426086956521739,0.5031525851197982,0.1102850061957868,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0021686917924136,0.0045547688125139,0.0067523658665366,0.0089241246124917,0.0112540192926045,0.0133374089357583,0.0157794347147563,0.0180269433862055,0.0201779505011249,0.0224891701741989,0.0248173834537097,0.0269003925114568,0.029117519916013,0.0310991957104557,0.0332331277569446,0.0355849423646033,0.0375588314569467,0.0397607501479735,0.0419194073642483,0.0437679195120679,0.0590282131661442,0.0730478325546313,0.0857962064402293,0.0982703408755741,0.1107895431740163,0.1259110169491525,0.1401972453664342,0.1540290677216067,0.1673389901238002,0.1792676770389147,0.194293668864453,0.2038115060652379,0.2126368538591426,0.2215004764982309,0.2297939428684828,0.2392766751032369,0.2478575104607191,0.2566306788055189,0.2642376796422516,0.2710357659706429,0.2778699460525552,0.2842583036216926,0.2908631309115507,0.2963425320193496,0.3013175342765727,0.3058576631072156,0.3112456595589986,0.3157204016105193,0.3193309996110463,0.3227327978015009,0.3212812980082473,0.319766081871345,0.3177887323943662,0.3169709321654164,0.3150833506671024,0.313063442259126,0.3117865906752157,0.3127850136150388,0.3126836100293776,0.31375,0.3143151390319258,0.3155141441459226,0.3164747434638132,0.3172538432361275,0.3199682890501129,0.3210153236735119,0.3223934929753711,0.3245597543397882,0.3278591352859135,0.330842444741603,0.3345081559802991,0.3393669892754381,0.3403847343353745,0.3452790662875954,0.3448689553340716,0.3493246390312063,0.3504828002414001,0.3478948408776438,0.3540086673889491,0.3528969149736644,0.0,1.855695494004438,58.208016215738105,171.9748568647615,259.0919679385561,fqhc8_implementation,49 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-100000,95719,44495,421.7240046385775,6086,62.32827338354977,4865,50.25125628140704,1861,19.076672343004,77.38113022984923,79.73310999148359,66.21410328630688,68.07341052868944,77.1485572747243,79.50262469943281,66.11263193166916,67.97579688000937,0.2325729551249367,230.48529205077276,0.1014713546377237,97.61364868006694,128.60892,95.7409218822633,134360.9105820161,100022.90233105578,258.49343,183.4719258683628,269627.7959443789,191250.9803365714,270.35062,148.84101405565343,279706.95473208034,153226.11271322274,3235.9324,1711.2033289237604,3342659.566021376,1749737.501356847,868.60174,445.3521726249514,893779.8556190515,451600.5940565103,1634.92753,797.3478826011969,1676605.2403389087,804391.651308648,0.38064,100000,0,584586,6107.314117364369,0,0.0,0,0.0,30671,319.83200827421933,0,0.0,34201,353.69153459605724,1285138,0,56429,0,0,0,0,0,70,0.7208600173424294,0,0.0,1,0.0104472466281511,0,0.0,0.06086,0.1598886086591004,0.3057837660203746,0.01861,0.3391521197007481,0.6608478802992519,24.310053757830705,4.381559690648003,0.327235354573484,0.2339157245632065,0.2154162384378211,0.2234326824254882,11.247649021204085,5.806787399684488,19.828192403796137,12294.840188651611,55.484649729488574,13.81289044157665,18.04991074404108,12.151494006903569,11.470354536967282,0.5741007194244604,0.8075571177504394,0.7054020100502513,0.593376264949402,0.1011450381679389,0.7364914877868246,0.9232456140350878,0.8647342995169082,0.7286821705426356,0.1255605381165919,0.5116676152532726,0.7302052785923754,0.6494057724957555,0.5512665862484921,0.0945454545454545,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022779504520466,0.004225523377176,0.0065523222200809,0.0088845115041731,0.0111199203106259,0.0132078351564487,0.015212031055774,0.0175687394786512,0.019780129960358,0.0219261896722837,0.0239759011455152,0.0259265721705036,0.027902864310242,0.0300153423190584,0.0319682277697544,0.0339977885936902,0.0360378081227418,0.0380214330916145,0.0401854874764761,0.042327490986391,0.0562134502923976,0.0704732402620507,0.0844968477588142,0.0975048105737989,0.1096245690609482,0.1249021805799369,0.1402051575809651,0.1534530666127263,0.1668180409672283,0.1791161643247881,0.1936150962905519,0.2034531283827668,0.2129877478183282,0.2222453336252668,0.2296438289762148,0.2398331595411887,0.2494048483900171,0.2579965761138892,0.2654271882173785,0.2726542324246772,0.2792563986593837,0.2863120633878757,0.29281368235029,0.2989613976106141,0.3045323539784266,0.3097019985944493,0.3135721525005943,0.317100763960391,0.3214646268540809,0.3250207594669759,0.3235238786315139,0.3225766601696543,0.3218145280287806,0.3207764861980444,0.3200718228764765,0.3184618912927146,0.3177274452739466,0.3190965900703636,0.3201118652160567,0.320603749376292,0.3210932103720574,0.3213954863506455,0.3231309583542398,0.3252146760343481,0.3263051968277548,0.3282587271124021,0.3290181859384737,0.3313241723922548,0.3331824039566716,0.3342120794806217,0.3374324324324324,0.3407047260560435,0.3439423136694225,0.3465421124001808,0.348065268065268,0.3495954028380438,0.3502576538344953,0.3512155917219208,0.3532967032967033,0.3511161558834658,0.0,2.241183758365651,59.3960441415155,183.93779346036808,258.3024119251767,fqhc8_implementation,67 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-100000,95692,44460,421.16373364544586,6015,61.562095054968026,4842,49.92057852276053,1937,19.75086736613301,77.30164125892453,79.68888815277556,66.16115393290289,68.05389652140896,77.04803738696695,79.43890700309906,66.04994402781773,67.94775148615058,0.2536038719575799,249.9811496765005,0.1112099050851611,106.14503525837904,129.03286,95.89985576074838,134841.61685407348,100216.98340587346,255.90902,181.727409617612,266929.962797308,189408.7380529323,264.37546,145.9969841620789,273623.0405885549,150301.1317876335,3257.10547,1733.441843323489,3360022.635121013,1767764.5292432895,871.93742,454.3358852797702,897090.5195836643,460697.098482392,1701.24829,846.4045814384523,1736927.9041090163,847743.7623171847,0.38091,100000,0,586513,6129.164402457886,0,0.0,0,0.0,30431,317.3097019604565,0,0.0,33424,345.6924298791958,1284883,0,56332,0,0,0,0,0,64,0.6688124399113824,0,0.0,1,0.0104501943736153,0,0.0,0.06015,0.1579113176340867,0.3220282626766417,0.01937,0.3330684887970761,0.6669315112029239,24.32946700564111,4.362722698283959,0.3145394465097067,0.2387443205287071,0.2259396943411813,0.2207765386204048,11.03979977840152,5.735215510000405,20.943572473747928,12266.19801094254,55.3758920273872,13.90837880599206,17.229342507024548,12.058700414458375,12.17947029991222,0.553490293267245,0.7794117647058824,0.6999343401181878,0.5500467726847521,0.1142595978062157,0.7167414050822123,0.919047619047619,0.8470873786407767,0.7011070110701108,0.1446808510638297,0.4911529680365297,0.6997282608695652,0.6453645364536453,0.4987468671679197,0.1059371362048894,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022090266096508,0.0045336064991835,0.006994568803614,0.0094217849556352,0.0113746197438167,0.0136987696569705,0.0159623838519833,0.0180873011009661,0.0201539924537562,0.0224456777734543,0.0243827413665819,0.0264836056314886,0.028432411303015,0.030471912890299,0.0324700784151877,0.0343683459781282,0.0365415480196738,0.0387600116197036,0.0407961647653414,0.0425778074253194,0.0575609450397944,0.0712835008375209,0.084147659882653,0.0969316890441516,0.1087998142519419,0.124192831283213,0.1391511187095815,0.1530453499275424,0.1660516999818183,0.1785794838196913,0.1934234098120049,0.2034219913908074,0.2119270254364742,0.2220298873745562,0.2299567825013229,0.2396741904698493,0.2490805638463172,0.2584357038205793,0.2654128669865599,0.2735143689364923,0.2806306254126751,0.2863599110174453,0.2924726088244003,0.2984340313193736,0.3030612493009458,0.3087680355160932,0.3130343351400068,0.3171759612936083,0.3204328139393074,0.3244243529753879,0.3236567113867727,0.3228799559471366,0.3207281135879757,0.3202886603901832,0.3183622496766424,0.316580374375785,0.3141305724417426,0.313900830243166,0.3143262362872082,0.3152199146413328,0.3155463285078367,0.3165241771477086,0.3177296051942612,0.3184978204984911,0.3209077345141262,0.3226184889723135,0.3225723875078218,0.3255923723213443,0.3295594822417381,0.334585114458072,0.3359028803545051,0.3374325782092772,0.3404064936725041,0.3395850876521473,0.3441960931630353,0.3466177861873226,0.3518149793230203,0.3609539207760711,0.3592259471245571,0.3611428571428571,0.0,2.602250221998179,58.26904108973915,187.4466029863652,255.1024952558789,fqhc8_implementation,87 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-100000,95722,44721,422.5152002674412,6044,61.72039865443681,4803,49.52884394392094,1961,20.02674411316103,77.33169993293536,79.68748180747706,66.19879195034616,68.06480202502848,77.08025975010978,79.43944757666235,66.08797315458585,67.95878150622507,0.2514401828255899,248.0342308147101,0.1108187957603092,106.0205188034189,128.44634,95.62046665999831,134186.85359687428,99893.92894005384,257.51689,183.1260509617574,268547.2932032343,190831.78471172505,269.11046,148.6208284662936,278172.8233843839,152755.87566324882,3245.40741,1733.074205680835,3348139.1738576293,1768216.8944243088,896.88981,460.5718949086592,924142.2765926328,468324.4759915782,1717.7996,854.5297375226346,1755922.9853116316,858694.1445398022,0.38194,100000,0,583847,6099.402436221559,0,0.0,0,0.0,30653,319.56081151668377,0,0.0,33985,351.0896136729279,1285229,0,56404,0,0,0,0,0,70,0.7208374250433548,0,0.0,1,0.0104469192035268,0,0.0,0.06044,0.1582447504843692,0.3244540039708802,0.01961,0.3321254135812195,0.6678745864187805,24.180023903676823,4.458928397861391,0.3243805954611701,0.2215282115344576,0.2188215698521757,0.2352696231521965,11.421079011746896,5.933123370363322,21.15314326625196,12298.005703342222,54.91887539159035,12.96636225325653,17.666103447843195,12.603577903556705,11.682831786933924,0.5577763897564022,0.8054511278195489,0.6912708600770219,0.5460176991150443,0.1217887725975261,0.7132459970887919,0.9214285714285714,0.8669833729216152,0.7050359712230215,0.1254901960784313,0.4954797317002041,0.7298136645962733,0.6262093227792436,0.494131455399061,0.1206030150753768,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023388378709487,0.0046103961900901,0.0069276100252558,0.0092107401088634,0.0114389718143734,0.0137428359105392,0.0158194624236802,0.0181400571661902,0.0201304543409806,0.0226802645860211,0.0248323661492402,0.0270975161465873,0.0290446619509787,0.0314578742508804,0.0332666281564614,0.0355478397453782,0.0376423100807286,0.0396436017384269,0.0419581146390895,0.0437671860678276,0.0586490973447631,0.0726688506745653,0.0867065365648935,0.0992646672066821,0.1121120698748918,0.1275191215208353,0.1423129569304882,0.1559978712080894,0.1685063096370222,0.1818776543262837,0.1971433495626696,0.2061748568831365,0.2152529284447973,0.2239250046489241,0.2322124166464931,0.2407708921747798,0.249617818047915,0.2584231730098354,0.2655662894052741,0.272087317419917,0.2784350040513948,0.284771621115687,0.2910813691815705,0.2969128547098755,0.3022080178877399,0.3066673240721338,0.3112630037180305,0.3158444071075811,0.3193839452395768,0.3227293135778992,0.3219557568649654,0.3207243405391273,0.3190443320607998,0.318565157116451,0.3170362004398739,0.3144226499456413,0.3124357331561546,0.3136081087730232,0.3142613151152861,0.3141705028012704,0.3154855643044619,0.3163521391166881,0.3169018514247373,0.3187520966118752,0.3205143641486262,0.321434163143886,0.3241002772775348,0.328078599860997,0.3299501361530572,0.331785614217668,0.333348678758862,0.3361892445306606,0.3378708103249004,0.3420296606879416,0.3493190101668905,0.3510728573160383,0.3524538918412003,0.3581874356333676,0.3646067415730337,0.3650175301908843,0.0,2.489259332872129,60.2028591298708,173.2168154126973,260.5364791895578,fqhc8_implementation,97 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-100000,95719,44577,424.0223988967708,5979,61.32533770724726,4685,48.38119913496798,1870,19.181144809285517,77.3818846176159,79.759582499838,66.20998914498811,68.09464605522984,77.142733182223,79.52059691985802,66.10677777271846,67.99397970798083,0.2391514353928983,238.98557997998185,0.103211372269655,100.66634724901746,129.11316,96.05116886042876,134887.70254599402,100347.02500070912,256.23939,181.75287497742968,267272.8925291739,189454.99323794607,261.79325,144.27933154460973,270616.2830785946,148374.66888106277,3130.87062,1651.2484215472364,3235625.5288918605,1689937.3008819642,852.85975,435.9504349973488,880969.5776178188,445454.9838871288,1640.90886,801.0119853668887,1684880.5357348071,811335.6841745788,0.38216,100000,0,586878,6131.259206636091,0,0.0,0,0.0,30455,317.58585024916687,0,0.0,33037,341.2802056018137,1288541,0,56476,0,0,0,0,0,72,0.7522017572268829,0,0.0,0,0.0,0,0.0,0.05979,0.156452794640988,0.3127613313263087,0.0187,0.3281621022637327,0.6718378977362672,24.57359681901256,4.353377300110665,0.3184631803628602,0.2388473852721451,0.2249733191035219,0.2177161152614727,11.24864659121216,5.946050375522061,19.930052797864864,12212.450826875778,53.0305346346732,13.41000206542985,16.70937046924866,11.38648436545303,11.524677734541664,0.5502668089647812,0.7810545129579982,0.67828418230563,0.5794117647058824,0.0958254269449715,0.7176656151419558,0.903846153846154,0.8586118251928021,0.7224489795918367,0.1055045871559633,0.4881474978050922,0.7083926031294452,0.614687216681777,0.5341935483870968,0.0933014354066985,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0020565917310829,0.0043603914211833,0.0067086847527124,0.0089010821521109,0.0112012045618711,0.0132096225531134,0.0153863409262393,0.0176695758689327,0.0197613911692241,0.0219093933964678,0.0240621700037933,0.0259214755933491,0.0276677809205451,0.0294844851032266,0.031456082231648,0.0333774505749028,0.0352129456007127,0.0370774037513364,0.0390566508609932,0.040870344511369,0.0547068344384691,0.0689590222259428,0.0818910357270228,0.0951073809974548,0.1070257388993747,0.1232261066345198,0.1377587286094696,0.1523673677935791,0.1652653283618764,0.1773802629603414,0.1936008443180839,0.2022971350702443,0.2114588202045674,0.2204527320224289,0.2292324100849945,0.2383034785111706,0.2479619944017575,0.2567347351622293,0.2644248750467512,0.2708774419482942,0.2770878340130082,0.2838178633975481,0.2908386304024197,0.2974093016013702,0.3027090694935218,0.3076477832512315,0.3128026123184326,0.3171010952944319,0.3207784136520185,0.3243938474527082,0.3234795250787497,0.3222619702806824,0.321522623892746,0.3199693601769016,0.3187717162118017,0.3170436620365407,0.3150060176094255,0.3153769206802119,0.3163773404726988,0.3179537366548042,0.3196545485068363,0.3214595148078135,0.3221134784332547,0.3224434348833066,0.3226762954637844,0.3231195607128056,0.3235877949183303,0.328450053101768,0.3316797093348239,0.3348104771702144,0.3376599800308614,0.3388626848269648,0.3413207547169811,0.3413305078331946,0.3438658265381764,0.3443988269794721,0.351857490864799,0.3524965187984881,0.359375,0.3524408284023668,0.0,2.1520657689071907,55.50981848976682,172.97006049013115,256.4417913209352,fqhc6_implementation,65 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-100000,95793,44280,418.50657146138025,6085,62.21748979570532,4826,49.83662689340557,1893,19.35423256396605,77.4063857673964,79.72364434354999,66.24360769983201,68.07739611473033,77.16891394185842,79.48691332996786,66.14088609379748,67.97707029257252,0.2374718255379804,236.7310135821299,0.1027216060345352,100.3258221578136,124.4089,92.52440886952816,129872.64205108932,96587.8601458647,247.68043,175.74093628884938,258117.0127253557,183018.1080964677,261.99346,144.81419934983728,270641.8423058052,148834.91797229648,3239.23484,1706.3487432480651,3349364.755253515,1749157.9585648894,871.62603,448.0988463634972,899088.8791456579,456962.4157953062,1667.72531,817.4470479559162,1708349.388786237,826157.6818621613,0.38024,100000,0,565495,5903.301911413151,0,0.0,0,0.0,29391,306.20191454490407,0,0.0,33092,341.7368701262096,1318018,0,57805,0,0,0,0,0,62,0.6367897445533598,0,0.0,0,0.0,0,0.0,0.06085,0.1600305070481801,0.3110928512736237,0.01893,0.3390759592795614,0.6609240407204385,24.442753146572752,4.454516968081647,0.3228346456692913,0.2229589722337339,0.2200580190634065,0.2341483630335681,11.414660608535822,5.900120899185882,20.304842085481848,12343.585104631758,54.6864482365585,12.867170524424122,17.606399238452,12.553810846424538,11.65906762725783,0.5638209697472026,0.7788104089219331,0.6989730423620025,0.5982300884955752,0.1111111111111111,0.7201800450112528,0.895,0.8497652582159625,0.7757352941176471,0.1234042553191489,0.5041511594617807,0.7100591715976331,0.642226148409894,0.541958041958042,0.1076178960096735,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023687806853267,0.0045798587539136,0.0069363458437699,0.0092069067026686,0.01137021795458,0.0136008056722582,0.0155611907162425,0.0177952274117887,0.0203506478919261,0.02245605423812,0.0246118235077225,0.0268005497548667,0.0288763791013498,0.0310126973020805,0.0330006804264005,0.0349734111208632,0.0368826170622193,0.0389011512834063,0.0408142070827707,0.0428233873570038,0.0576579960559677,0.0722464472817391,0.0863782152065907,0.0989878393575985,0.1108441859484974,0.125834883327697,0.140647363789612,0.1551364690365264,0.1680206676416897,0.1811695129529237,0.1959552495697074,0.2052260589418149,0.214169257190061,0.2240889316398137,0.2327453481722605,0.241036717062635,0.2499330715688024,0.2586978522433374,0.266365151154487,0.2729603222742306,0.2796156470057699,0.286419406528884,0.2927192909798724,0.2993719887820897,0.3045542294476889,0.3095287932329438,0.3140185981401859,0.3185267091165593,0.3219942334794358,0.3260966993567436,0.3250033606667563,0.3235924785572905,0.321852514186744,0.3199722667591108,0.3191280848157277,0.3171437318230522,0.3153809674359785,0.3166330694724421,0.3171571803703577,0.3178049040891135,0.3190540187404338,0.3205597543693906,0.3214494569757727,0.3229981066933957,0.3251318944844125,0.3258447441037121,0.3276641733739086,0.3317245918079539,0.3358417920896044,0.3374792046264754,0.3405530581664623,0.3415915119363395,0.3428967778548458,0.3446821562763592,0.3489161168708765,0.3534503201327958,0.3579493439121147,0.3659971596672753,0.3664289632473944,0.3756694720734506,0.0,1.938506462471004,58.918107161558005,174.6739865490512,263.5294326733321,fqhc4_implementation,12 -100000,95726,43865,414.58955769592376,6182,63.38925683722291,4846,50.02820550320707,1938,19.89010300231912,77.41869514561299,79.7789375539144,66.23102992785275,68.09833487393625,77.17509680563882,79.5356957349835,66.12716483940635,67.99718037288007,0.2435983399741701,243.2418189308976,0.1038650884463976,101.15450105618606,122.628,91.23222876558016,128103.1276769112,95305.58966799005,247.87323,175.49924172304773,258477.1430959196,182871.781671696,259.6834,142.963801245735,268293.0969642521,146899.11422011227,3294.39989,1730.6842869717675,3408482.617052838,1774949.822380303,905.62435,463.6032351071804,934212.1053841172,472455.5137655189,1708.97748,826.3501762673641,1756630.0378162672,838800.6371933585,0.37714,100000,0,557400,5822.869439859599,0,0.0,0,0.0,29434,306.8340889622464,0,0.0,32838,338.9988091009757,1328055,0,58131,0,0,0,0,0,59,0.6163424774878299,0,0.0,1,0.0104464826692852,0,0.0,0.06182,0.1639179084690035,0.3134907796829505,0.01938,0.3312826822516149,0.6687173177483852,24.684844258015563,4.487249816345342,0.3330581923235658,0.2234832851836566,0.2298803136607511,0.2135782088320264,11.415273178889889,5.718865846075321,20.535102802372013,12231.260896159123,55.00812136015982,13.042282849630093,18.330055263333577,11.463066700298508,12.17271654689764,0.5610813041683863,0.7876269621421976,0.70817843866171,0.5603864734299517,0.1283662477558348,0.7146153846153847,0.9115479115479116,0.8628841607565012,0.6978723404255319,0.1234042553191489,0.5047941342357586,0.7130177514792899,0.653232577665827,0.52,0.1296928327645051,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022381106700153,0.00457181088314,0.0068493150684931,0.0089904305247973,0.0114090479241023,0.0135140639957634,0.0157225009176556,0.0178957899465065,0.0201030190299041,0.0226500450339801,0.0247122372210776,0.0267639902676399,0.0287834865026007,0.0309208290859667,0.0327375119903458,0.0347970773348766,0.0367194780987884,0.0386079955176957,0.0407573378804104,0.0428504453820909,0.0574680240146175,0.0713725244028749,0.0843736231458364,0.0966079410991322,0.1085704642774273,0.1251891274216245,0.1397214910418612,0.1538707306942713,0.1666524164760703,0.1792767568843261,0.1945632616120586,0.2032685751393473,0.2126729313495171,0.2210815184116155,0.2295585032666798,0.2392206785852659,0.2479761825115407,0.2560808380541318,0.2630600820433787,0.2694200311269797,0.2765627710634361,0.2824196376388077,0.2886808731931591,0.2945244818838846,0.3002958579881656,0.3053252982412987,0.3107125908534605,0.3148094046515172,0.3191426135042249,0.3223614914682958,0.3219247165776839,0.3206919768608214,0.3198621950362089,0.3188274141685051,0.3190832900689757,0.3174826457906486,0.3168280795037346,0.3173679205063457,0.3167965618977778,0.3169640469866847,0.3172443479562808,0.3192570561934963,0.3205181693020151,0.3215821727019499,0.3227143165105751,0.3247581753585228,0.3251259410199807,0.3270267743041486,0.3304999479582278,0.3316392353102154,0.3345309201958054,0.3394562821454812,0.3422935722730384,0.3467838893898406,0.3478099480326652,0.3477395174513937,0.350722433460076,0.3504616619831393,0.3516304347826087,0.3587038432554634,0.0,2.380851037239504,57.0063176298257,184.168651213678,261.16010815326166,fqhc4_implementation,13 -100000,95670,44326,419.7031462318386,6046,62.06752377965925,4833,49.80662694679628,1919,19.5986202571339,77.2656064282761,79.64703825792958,66.14809085222389,68.03374916295144,77.01752114543665,79.40138862575536,66.04082034499494,67.93062424237907,0.2480852828394546,245.6496321742208,0.1072705072289466,103.12492057236966,123.10826,91.608670006559,128680.10870701369,95754.8552383809,247.88158,176.07461668032627,258551.71945228396,183494.7911365384,263.18765,145.2805419212102,271712.65809553675,149027.09918075378,3243.05937,1716.3419713103258,3345806.8673565383,1749990.625389699,887.20289,457.4360030572148,913273.0532037212,464055.0256686676,1694.89636,835.9680017733475,1733028.7132852513,838797.3897328066,0.38033,100000,0,559583,5849.095850318804,0,0.0,0,0.0,29413,306.6896623811017,0,0.0,33258,343.11696456569456,1316732,0,57781,0,0,0,0,0,69,0.7212292254625274,0,0.0,1,0.0104525974704714,0,0.0,0.06046,0.158967212683722,0.3173999338405557,0.01919,0.3331756543677073,0.6668243456322926,24.11451438234404,4.430916370966862,0.3153320918684047,0.2350506931512518,0.2288433685081729,0.2207738464721705,11.184831404884964,5.682646676002332,20.79559168713233,12226.880622350556,55.368354701193816,13.655305878251127,17.490776076146325,11.954772489347452,12.26750025744891,0.5545210014483758,0.7772887323943662,0.6837270341207349,0.5932521087160263,0.1103074141048824,0.7155490051584378,0.9408983451536644,0.8524590163934426,0.7023809523809523,0.1254901960784313,0.4916570771001151,0.6802244039270687,0.618049225159526,0.5595092024539877,0.1057579318448883,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023898976192163,0.0045918522498048,0.0068497320993667,0.0090832427379779,0.0111573315975224,0.0134408602150537,0.0158002038735983,0.0177410299596794,0.0198491383715938,0.0221571777998383,0.0240387079578886,0.026114270463364,0.0284063454203378,0.0304796424820314,0.0326084713940869,0.03467622777198,0.0366716017683539,0.0386343123320642,0.0408209948427882,0.0427633635511097,0.0577272632304703,0.0715385179212783,0.0844958066987855,0.0969809216134022,0.1087208811613774,0.1244311326545731,0.1384322969758749,0.1523205626898278,0.1654937862291715,0.1782388761800431,0.1925002697744685,0.2011081113315768,0.210998376181083,0.2209520260420662,0.2292688843070884,0.2382744418911868,0.2466370721561874,0.2549958860723826,0.2625620858574952,0.2698199593789803,0.2768783246607252,0.2835380144370488,0.2898681339531354,0.2961272891023717,0.3017836488707615,0.3067870285756625,0.311652810693551,0.3160600609794991,0.3195142541723488,0.3233978346613018,0.3230349226943453,0.3220252324954744,0.3218304682198598,0.3207738716788491,0.3198890247904298,0.3176385534755657,0.3152757908122715,0.3162547951069329,0.3167957239772493,0.3170146044261266,0.3177614105148153,0.31951544566666,0.3203918264166842,0.3206436244325588,0.3229773150049525,0.3243652700867203,0.3235403389442999,0.3259715639810426,0.3293552715203728,0.3339592489013184,0.3366617808721143,0.3401158157573182,0.3443324937027708,0.347148288973384,0.3501930865592917,0.3517044779665043,0.351787072243346,0.3519564340459863,0.3517615176151761,0.3592523364485981,0.0,2.7480967199830144,59.36662837967143,179.33303134311188,260.83529361616013,fqhc4_implementation,14 -100000,95803,44201,417.8261641075958,6004,61.2924438691899,4730,48.65192112981848,1846,18.76767950899241,77.38309434870726,79.6962065068303,66.22077513463483,68.05317575108025,77.14819980571825,79.4669260295432,66.11832466105335,67.95673956782967,0.2348945429890108,229.2804772870909,0.1024504735814844,96.43618325057446,123.50096,91.87245845947004,128911.37020761354,95897.26674474707,247.50748,175.34993486680676,257806.4674383892,182487.797737865,258.05309,142.35133701027698,266021.366763045,145772.82063706467,3183.03285,1680.6435138254246,3277540.859889565,1709333.8766274808,859.98798,439.7926555234649,884044.716762523,445441.2028051983,1630.9779,799.6446655634669,1660817.6361909334,797616.6847231558,0.38015,100000,0,561368,5859.607736709707,0,0.0,0,0.0,29393,306.06557205933007,0,0.0,32532,335.2504618853272,1321698,0,57911,0,0,0,0,0,76,0.7724184002588645,0,0.0,0,0.0,0,0.0,0.06004,0.1579376561883467,0.3074616922051965,0.01846,0.3364589955499046,0.6635410044500953,24.27995376297609,4.341286161497897,0.3291754756871036,0.2319238900634249,0.2245243128964059,0.2143763213530655,11.307616258376756,5.835974528306207,19.673040147472527,12260.887037358463,53.63256672833421,13.237784715074204,17.396288911728636,11.408402466684656,11.590090634846698,0.5706131078224101,0.8030993618960802,0.6865767501605652,0.6232741617357002,0.1101694915254237,0.7273431448489543,0.928406466512702,0.8367875647668394,0.756198347107438,0.1347826086956521,0.5117766792672288,0.7213855421686747,0.637062339880444,0.5816062176165803,0.1033653846153846,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022372723499458,0.0044683114646132,0.0068354918207356,0.0091176769215148,0.0115276704753385,0.0138535453268459,0.016166517165457,0.0182692209555108,0.0203683263837789,0.0225449261124073,0.0247342579210102,0.0267786551118686,0.0289883388519836,0.0307340536197999,0.0328237502836747,0.0346070805053666,0.0366364812419146,0.0386051141666148,0.0408468554569819,0.0426654731298075,0.0573875668965229,0.0713613550815558,0.083971146385959,0.0967294288327498,0.1083796291415861,0.1238924954008162,0.1384780142295172,0.152010812306448,0.1649041850926104,0.178045903045903,0.1925450452876113,0.2021514918669711,0.2114685984032717,0.2203176617296375,0.228198410426895,0.23794739876702,0.2470623715485658,0.2560490908067331,0.2634908735702684,0.2714957020057306,0.2781668538090222,0.2847660411374252,0.2907943349753694,0.2964113512605848,0.3018425338486594,0.3070998114439939,0.3122349674142827,0.3174429548981201,0.3214835911709496,0.3251414776999485,0.3245806373505159,0.3238414600626683,0.323231612993953,0.3222440319833732,0.3212382945253254,0.3190809099114259,0.3171449362482994,0.3181818181818182,0.3182453627932351,0.3187956529485123,0.3202647372258679,0.3210781904331243,0.3224112056028014,0.3232584595480806,0.3237472140340786,0.3243649949407156,0.325087236517348,0.3279230913290467,0.3309981876481249,0.3326365608361269,0.3345601599418393,0.3359432864247169,0.341198619391277,0.3455676044589368,0.3508902768714458,0.3535054476551397,0.3521234341582646,0.3505030181086519,0.3624792473713337,0.3603254552499031,0.0,2.8123681895025507,55.95756445676774,175.02636448225846,256.9926526616192,fqhc4_implementation,15 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-100000,95793,44468,420.3647448143393,6179,63.29272493814788,4890,50.50473416637959,1977,20.283319240445543,77.31829074272538,79.65173115371614,66.18746572751799,68.03910524359115,77.0780882769182,79.41135194524786,66.08348471049082,67.9370985335351,0.2402024658071866,240.37920846828345,0.1039810170271664,102.00671005604534,123.26402,91.68726063273164,128677.48165314792,95713.94635592542,247.53687,175.31417209605218,257998.83081227227,182604.28433815847,265.71281,146.63861098468283,274142.3172883196,150511.8194795837,3291.85633,1730.844714848049,3401230.507448352,1771662.9866984535,917.33247,479.0978170962012,945504.0660591066,488036.4230096872,1736.30889,842.8023803748073,1782278.7886380006,853824.0763248889,0.38243,100000,0,560291,5848.976438779451,0,0.0,0,0.0,29410,306.4420155961291,0,0.0,33518,345.88122305387657,1320013,0,57918,0,0,0,0,0,59,0.5845938638522648,0,0.0,1,0.010439176140219,0,0.0,0.06179,0.1615720524017467,0.3199546852241463,0.01977,0.3272223078108149,0.672777692189185,24.38189435851658,4.449820549606634,0.3198364008179959,0.2353783231083844,0.223721881390593,0.2210633946830265,11.483535526081354,5.959338707096762,21.02294651040145,12444.11589110607,55.471663617459015,13.912187291380205,17.675403413252265,11.927660658133586,11.956412254692946,0.5693251533742332,0.787141615986099,0.7078005115089514,0.5883441258094357,0.1234003656307129,0.7473684210526316,0.9327146171693736,0.8823529411764706,0.7238493723849372,0.1872340425531914,0.5028089887640449,0.7,0.6426690079016681,0.5498812351543944,0.1059371362048894,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022582735852878,0.0047034495342165,0.0067985104159267,0.0090099241216085,0.011379699592202,0.0136625095444133,0.0160050563744979,0.0181406127178251,0.0203599791494189,0.0224130343564184,0.0245854598372584,0.0268672646292153,0.0287071012303043,0.0306450284207924,0.0326872891932871,0.0350931580742164,0.037012106086182,0.0392020581339861,0.0412816861885113,0.0431513838848741,0.0583484630313654,0.0723071773738049,0.0862900520046971,0.0993577277648716,0.1118502899314707,0.1276111904384155,0.1423722701286579,0.1567249968067441,0.1701452681051057,0.1827707884209058,0.1977069953881298,0.2070824627310028,0.2162235692287601,0.2253433276795973,0.2336485638479407,0.2429861996342071,0.2514519299499642,0.2598243441053935,0.2674501788451712,0.2741835682365074,0.2820717500202455,0.2896813797135341,0.2961998650839674,0.3015564901685898,0.307442697066187,0.3126333049771301,0.3175752715791056,0.3219861590813504,0.3248816548861941,0.3282784880415669,0.3269383738017877,0.3259242927420799,0.324150868878357,0.3243118204950266,0.3234865604186489,0.3213782542113323,0.3196725205466436,0.3210840304369977,0.32234714307716,0.3225881385915694,0.3238275467950759,0.3254034336465644,0.3257803468208092,0.3267193391991381,0.3267928166807279,0.3273745648703117,0.3290517782725352,0.3312574699628861,0.3325931408832963,0.336466464871754,0.3406929968915707,0.3441974780936097,0.3449850916703673,0.3443891229414018,0.3459720121028744,0.3457663708323339,0.3453304374806081,0.3486031224322103,0.3561719833564494,0.3592009220130618,0.0,2.0610793551081223,58.47832230783255,178.6546314045414,270.5226449187624,fqhc4_implementation,22 -100000,95667,44520,421.03337619032686,6260,64.09733763993853,4949,51.09389862753091,1994,20.34139253870196,77.31568461530958,79.72699305723236,66.16797476173758,68.08172736505027,77.06252511336747,79.4756134986043,66.05757965785716,67.97484742655345,0.2531595019421075,251.37955862805936,0.1103951038804211,106.87993849681732,122.68608,91.26043753412084,128242.38243072324,95393.40016319194,245.99241,173.85479298306376,256653.40190452297,181248.70956867444,261.95495,144.56329047868937,270984.7178232828,148706.61567713486,3312.60802,1762.4112393316766,3423900.50905746,1803525.9469113443,911.70407,475.9156924460909,939819.15394023,484309.17513885786,1745.04531,857.4851816855614,1783488.6428967146,862055.372610984,0.38251,100000,0,557664,5829.199201396511,0,0.0,0,0.0,29142,303.9606133776537,0,0.0,33154,342.6782485078449,1327372,0,58170,0,0,0,0,0,63,0.6585342908212863,0,0.0,0,0.0,0,0.0,0.0626,0.1636558521345847,0.3185303514376997,0.01994,0.3281131214839592,0.6718868785160408,24.407013728962,4.416667269873929,0.3192564154374621,0.236411396241665,0.2192362093352192,0.2250959789856536,11.561028014821511,6.063457170237589,21.408539247957705,12445.65516974535,56.58208210318778,14.066884709606573,18.060801840306887,12.528297147622544,11.92609840565177,0.5681955950697111,0.7752136752136752,0.7082278481012658,0.59245960502693,0.1161290322580645,0.7309064953604568,0.900709219858156,0.8688888888888889,0.7220338983050848,0.167381974248927,0.503945885005637,0.7041499330655957,0.6442477876106195,0.5457875457875457,0.102112676056338,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023713492369119,0.0045839925357997,0.0068017542434824,0.0091373860367731,0.0113347306729614,0.0137223540917472,0.0160875686042478,0.0183473117510649,0.0207425590671985,0.0229985145725554,0.0251290312650707,0.0271439730307515,0.0292246561805155,0.0313679391202128,0.0336570247933884,0.0358258997868245,0.0375623360600499,0.0395528358146928,0.0415348430605278,0.0435226893560226,0.0588278311742582,0.0730527638190954,0.0866033478511832,0.0991117098532847,0.1110079155672823,0.1269275138378824,0.1411041642340802,0.1553683448180375,0.1689845745988647,0.1813343062873576,0.196535405909429,0.2060457109448588,0.216135913454213,0.2257521058965102,0.2339924255768892,0.2426039438243346,0.2519177730384001,0.2604564235935195,0.2680301154881275,0.2754296064472492,0.2824813631522896,0.2887892691605412,0.2953977965279339,0.3012963362327175,0.3062577402200043,0.3109835702145478,0.3160829020725518,0.3204927922778942,0.3240307270517031,0.3283735519327332,0.3283037661183945,0.3269402625970991,0.3256911095776592,0.3249989147892521,0.3242213657534858,0.3221707945071113,0.3212037827750894,0.3223778175430532,0.3220845281988256,0.3222644743184618,0.3241738674064216,0.3239149777558082,0.3242903266384335,0.3259643784122438,0.3272639691714836,0.3272955711443828,0.3284579786322344,0.3313568409764713,0.3340371621621621,0.3387425556577002,0.342607422321878,0.3460059803502777,0.3444773859837254,0.3435606351154406,0.3451043338683788,0.348486646884273,0.3489591364687741,0.3528568502969486,0.3520775623268698,0.3532752745172283,0.0,2.485792940960893,61.457587997961525,183.8797207176492,263.7052476200869,fqhc4_implementation,23 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-100000,95689,43950,417.1848383826773,6111,62.807637241480215,4783,49.45187012091255,1891,19.36481727262277,77.2828175392554,79.66994574311838,66.1599748218603,68.05207340875242,77.04474476519668,79.43463819607753,66.0564698897933,67.95287145114479,0.2380727740587218,235.307547040847,0.1035049320669969,99.20195760763306,122.95206,91.5495325846766,128491.32084147604,95674.04046930851,248.23642,175.78289958000593,259027.39081817132,183309.67987961616,259.51077,142.99546063425245,269180.8044811838,147688.17552675618,3201.66985,1699.6298579712195,3309721.723500089,1740011.52480559,880.80469,453.04603801637006,910548.8196135396,463521.7402443028,1663.91982,810.7574692060227,1705223.1917984304,816946.7458981558,0.3779,100000,0,558873,5840.514583703456,0,0.0,0,0.0,29439,307.0990395970279,0,0.0,32902,341.0736866306472,1321072,0,57942,0,0,0,0,0,62,0.647932364221593,0,0.0,0,0.0,0,0.0,0.06111,0.1617094469436358,0.309441989854361,0.01891,0.3348402182385035,0.6651597817614965,24.3249326548628,4.256589705998232,0.3221827305038678,0.2329082166004599,0.2161823123562617,0.2287267405394104,11.197054170841684,5.929711777358624,20.259019246451075,12218.305873417354,54.67527184674013,13.44534702084927,17.525185060547376,12.213063098312976,11.491676667030497,0.5705624085302111,0.781867145421903,0.7144711226476315,0.5923217550274223,0.1054158607350096,0.7373887240356083,0.9090909090909092,0.8973105134474327,0.7410358565737052,0.1308016877637131,0.50509461426492,0.6953242835595776,0.6484098939929329,0.5480427046263345,0.0978670012547051,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022796583552011,0.0044522423480253,0.0065273223766356,0.0084554564117156,0.0103772433158344,0.0125070020878953,0.0146638929678577,0.0168361512701135,0.0189018717862217,0.0209563979975224,0.0232653521588893,0.0255612381128432,0.0273331413052423,0.0293757019360555,0.0314880178339216,0.0333567706179171,0.0352902169633421,0.0373215676096548,0.0392360822168594,0.0412450632014422,0.055365779769553,0.0694392092808979,0.0828278163766503,0.0957921312855038,0.1080077630579697,0.1230157471154964,0.1379676194113777,0.1517455044875275,0.1642955631326357,0.176660551246151,0.1918286428479076,0.2019361964784614,0.2118395995429566,0.2204259883542752,0.22847481523092,0.2376092647646093,0.2467111513485117,0.2558899417484479,0.2641041960267309,0.2716730517767429,0.2794584327442033,0.2863411894118473,0.2926182442431776,0.2992747107834322,0.3047965186949968,0.3085426639688101,0.3129239758749106,0.317295669703233,0.3211017510156929,0.3249702577660278,0.3241133891382587,0.3226934728724869,0.3221863045411555,0.3218144425455493,0.3197789594411427,0.3179203166469785,0.3155456117802002,0.315911826290538,0.3167253067879516,0.3175778658394448,0.3194598559365067,0.3196561854851517,0.3201045928050272,0.3217097862767154,0.3233057292546898,0.3235132662397072,0.3247624211637795,0.3283882956943525,0.3303285326948132,0.3330278519344942,0.3352801606132506,0.3381711855396065,0.3417618270799347,0.3446808510638298,0.3476257639868359,0.3479191438763377,0.3483353884093711,0.3487948146647762,0.3480055020632737,0.3432835820895522,0.0,2.1020883034205102,59.37407779028726,179.18769723968092,254.18840828845745,fqhc4_implementation,26 -100000,95679,44213,418.576699171187,6315,64.76865351853594,4901,50.57536136456275,1955,20.077550977748512,77.38477840256228,79.77267495417016,66.2115714317079,68.10294569575333,77.14206507419772,79.53035672036083,66.10827320023373,68.00186557732702,0.2427133283645588,242.3182338093284,0.1032982314741701,101.08011842631016,123.00002,91.48835544113292,128554.8762006292,95620.09996042278,248.06883,175.55072891906875,258774.31829346044,182981.19641621332,263.329,145.03428174243734,271653.23634235305,148634.53987991204,3303.50468,1743.3861127046357,3416476.081480785,1785900.3362332757,907.27713,458.9706616808596,938765.2462922898,470212.6189454948,1715.444,826.4969685065662,1764139.7903406182,840287.0786545706,0.38036,100000,0,559091,5843.403463664963,0,0.0,0,0.0,29430,306.9116525047294,0,0.0,33193,342.10223769061133,1325882,0,58116,0,0,0,0,0,84,0.8779355971529803,0,0.0,1,0.0104516142518211,0,0.0,0.06315,0.1660269218634977,0.3095803642121932,0.01955,0.3305685416980847,0.6694314583019152,24.64009032790108,4.3654687108594,0.3262599469496021,0.2277086308916547,0.2211793511528259,0.2248520710059171,11.299649714260257,5.890261916004424,20.680778637224307,12364.973211110682,55.756414584141545,13.42639217249835,18.09110160830312,12.432256712842658,11.80666409049742,0.5782493368700266,0.8055555555555556,0.7041901188242652,0.6079854809437386,0.1282287822878229,0.744890234670704,0.9110576923076924,0.875,0.7642857142857142,0.1566820276497695,0.5167597765363129,0.7428571428571429,0.6456759026028548,0.5547445255474452,0.1211072664359861,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0020057335615952,0.0042484587929915,0.0065269248337816,0.0086580966414308,0.0107313599837249,0.0130875388297601,0.0155215843845926,0.0178821270642061,0.0201478875400145,0.0223048327137546,0.0244102564102564,0.0264136217059995,0.0284912006418234,0.0306517752271837,0.032585023481447,0.0343854061097437,0.0363851102845953,0.0382870961380784,0.0406662227955557,0.0427390520269777,0.0576081393041062,0.0713298574031032,0.0842413554197896,0.0975463479303886,0.1100269001529616,0.1260064114093462,0.1410197909481615,0.1552559040452953,0.1681635181170641,0.1809322669868565,0.195523448602558,0.2048869130674627,0.21403722386502,0.2234536730388781,0.2316582361996921,0.241028933212317,0.2500418036898723,0.2592434424939875,0.2661845222576147,0.2734728894989705,0.2812427759027232,0.2873426156490022,0.2942393888146457,0.3007314474519052,0.3055073378570301,0.3106582107013115,0.3155546111347216,0.3200238985076145,0.3236640629041436,0.3276562088056947,0.3269323931531919,0.3252405828979928,0.3238072445201526,0.3239062296881544,0.3231507195152739,0.3206348720460389,0.3188114741136658,0.3186411206981398,0.3192073066830249,0.3197916296269957,0.320554892601432,0.3218797969063643,0.3228238234069138,0.3233567553144179,0.3239156957967513,0.3251665759249177,0.3282035265055794,0.3314342953734427,0.3337632459564975,0.3382590534736178,0.3400661201938318,0.3448952532484752,0.3481934548206066,0.3501180772453721,0.3504941176470588,0.3550450023685457,0.3577925080931093,0.3621390809272062,0.3693072039746067,0.3635652853792025,0.0,2.531057543049211,57.7074169424094,184.38548755006565,267.7067369041136,fqhc4_implementation,27 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-100000,95717,44002,416.5090840707503,6286,64.50264843235789,4947,51.07765600676996,1968,20.1949496954564,77.35268390558021,79.74581498014027,66.18237796687838,68.08315149269112,77.10901752262856,79.50297651324654,66.07762478382753,67.98141197261593,0.2436663829516447,242.8384668937298,0.1047531830508461,101.73952007518494,123.68268,92.02483502657935,129217.04608376775,96142.62359516004,250.00684,176.6745285428373,260757.3785221016,184143.7033576452,261.8727,144.2627526302435,270504.6647930879,148216.9704569886,3340.29597,1759.9817581791997,3453447.9664009525,1802612.8340401505,934.49431,475.0703787750026,965497.0276962296,485574.2378818269,1734.65994,840.7376969774136,1782112.205773269,851918.9832966607,0.37785,100000,0,562194,5873.502094716717,0,0.0,0,0.0,29675,309.41212114880324,0,0.0,33078,341.43360113668416,1319722,0,57846,0,0,0,0,0,67,0.699980149816647,0,0.0,0,0.0,0,0.0,0.06286,0.1663623130872039,0.313076678332803,0.01968,0.3224681625227411,0.677531837477259,24.6810103149618,4.428332112041157,0.3147362037598544,0.2302405498281786,0.2288255508388922,0.2261976955730746,11.538737257510032,6.138791201945816,20.916861158079367,12262.961183882458,55.98799567958353,13.498283580584932,17.58613181634108,12.486155320117488,12.41742496254003,0.5591267434808975,0.7910447761194029,0.6917148362235067,0.5835567470956211,0.1192579505300353,0.706646294881589,0.9095744680851064,0.843520782396088,0.7035714285714286,0.1680327868852459,0.5060472787245739,0.7326343381389253,0.6376306620209059,0.5435041716328963,0.1058558558558558,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023207264177712,0.0044540492278971,0.006631798100848,0.0086416364209391,0.0111369003990552,0.0133939492783168,0.0156037922623968,0.0177077053552269,0.0197890126981203,0.0219186785260482,0.0238813628899835,0.0259071617219373,0.02773603935533,0.0299669096044615,0.0318983054347938,0.0340748094602839,0.0363525231282439,0.0386751227410967,0.0406685874166606,0.0425720389766036,0.0570569316235746,0.0716348870795571,0.0858809458864013,0.0981775735332779,0.1094921294295022,0.1248519333276927,0.1396133522908134,0.1527298667007367,0.1659240262862638,0.1788208037926485,0.1944211002650462,0.2044005067512695,0.2137516732508407,0.2223267619193488,0.2296639654716815,0.2389343263071569,0.2485601392981516,0.2572370419540294,0.2632725787048596,0.2703266236667545,0.2780098351171536,0.2845749967842651,0.2900851869380028,0.2954964887472138,0.3012228145377712,0.3065817514381798,0.3115145903198358,0.3165726797102741,0.3212191048331758,0.3253905425374709,0.3244287136974134,0.3215454420459233,0.3204501598659098,0.320127057464626,0.3190113053025132,0.3176290630975143,0.3159041738388895,0.3169609977250037,0.3169984686064318,0.3180160466812545,0.3192323488780196,0.3207941483803553,0.3222850702343929,0.3222732952516958,0.3240591559456535,0.3255777598290821,0.3261030038044404,0.3292698174543635,0.3337859480537567,0.3377182586710911,0.3396515931040708,0.341536519955829,0.3465749139818579,0.3516875237011755,0.3572564798353139,0.3601704949088326,0.3630632015992618,0.363876472978464,0.3701067615658363,0.3699421965317919,0.0,2.370317031788548,57.32235226778867,183.94841013735507,274.1226624580152,fqhc4_implementation,46 -100000,95681,44351,418.8814916232063,6238,63.816222656535786,4859,50.02038022177862,1921,19.596367094825517,77.28822072876713,79.65738721131477,66.17594254072044,68.05127127579294,77.0449482864884,79.41954901773283,66.0695588478442,67.95128718127565,0.2432724422787231,237.83819358193625,0.1063836928762356,99.98409451729628,123.2044,91.66981603570248,128765.79467187844,95807.75288270655,247.58281,175.29611921095497,258187.84293642416,182638.16140190308,259.82333,143.08141202320292,268507.0494664562,146964.04587647732,3231.18304,1698.8009226039085,3328912.981678703,1727359.7815699126,894.34066,457.6699815563075,919393.5577596388,463014.8317412787,1691.50367,822.5244180985125,1727061.1406653358,821063.2238703045,0.38187,100000,0,560020,5852.990666903565,0,0.0,0,0.0,29374,306.2049936769056,0,0.0,32906,339.8062311221664,1321073,0,57937,0,0,0,0,0,57,0.5957295596826956,0,0.0,0,0.0,0,0.0,0.06238,0.1633540210019116,0.3079512664315486,0.01921,0.3379204892966361,0.6620795107033639,24.51584968788953,4.352055553921836,0.331343897921383,0.2284420662687795,0.2226795636962338,0.2175344721136036,11.323985284230664,5.945910364404428,20.38201684683996,12391.025850265134,55.03955047596221,13.35116214953912,18.13558268548809,11.713604727286585,11.839200913648412,0.5571105165671949,0.7774774774774775,0.7024844720496894,0.5506149479659413,0.1210720887245841,0.7190923317683882,0.9025,0.8553921568627451,0.7231404958677686,0.1491228070175438,0.4993018709857582,0.7070422535211267,0.6505823627287853,0.4993865030674846,0.1135831381733021,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022784117950847,0.0046218870678383,0.0070614733723608,0.0094052165434305,0.0117318151781629,0.013953488372093,0.0160807092632222,0.0184499209143323,0.0207005067843714,0.0229598101006793,0.0250599348400713,0.0272624666529858,0.0295245044137746,0.0314783933460976,0.0334746155987996,0.0354906701382431,0.0377084994253647,0.0398277382867223,0.0419166658001185,0.0438960335160597,0.0586705383442311,0.0732866459399763,0.0867398329626054,0.0995307535298697,0.1106047659736067,0.1262230402267847,0.1407942621298447,0.1549220812398876,0.1678190153563375,0.1806495917250555,0.1952688867334842,0.2046084546084546,0.2136279525416349,0.2228789072760704,0.2318810268151996,0.2409141793112621,0.2498017623605356,0.2581993062125512,0.2663425052827702,0.2729588616673361,0.2796393096813825,0.2871447141903523,0.2938124178128443,0.2997542113782147,0.305505568795292,0.3095948879897365,0.3142864297071601,0.3195342326291677,0.3233563206471015,0.3277358665063615,0.3264483423440428,0.3244494029172348,0.3230921145436592,0.3224280133121111,0.3213239122350316,0.3201373243214247,0.3186266746904,0.3197697368421052,0.3211461435760501,0.3214713613848107,0.3231532089930692,0.3243597119447696,0.3254003324705932,0.3263815538126166,0.3267491900778492,0.3282709054663729,0.3305924822369929,0.3341451072174078,0.3363439946162292,0.3400216702114852,0.3445227241331676,0.3465432299279952,0.346310022558814,0.3472459270752521,0.3515302695960856,0.3542043672336832,0.3594333748443337,0.3632250102838338,0.3576912141029286,0.3571996817820206,0.0,2.8845195685939453,55.32687700448705,179.6981022044631,272.9963691409628,fqhc4_implementation,47 -100000,95576,44553,421.2040679668536,6196,63.739851008621415,4867,50.3473675399682,1942,19.900393404201893,77.21810735701168,79.67184396964072,66.1142194635241,68.06194613849688,76.96630041190151,79.42379003829853,66.00449705268196,67.95683077556717,0.251806945110161,248.05393134218437,0.1097224108421386,105.11536292970902,122.8634,91.47359121843633,128550.01255545329,95707.24639913396,247.67163,175.7935637425922,258698.76328785476,183493.8412808573,263.33462,145.80255234957008,272949.38059763954,150426.8439396498,3271.25841,1739.896077027906,3381050.1694986187,1778839.0655895907,888.0953,459.0462790215789,917345.860885578,468437.1170812546,1712.37461,848.0781031230554,1754637.1369381433,853447.6239180864,0.38149,100000,0,558470,5843.182388884239,0,0.0,0,0.0,29369,306.666945676739,0,0.0,33250,344.53210010881395,1318446,0,57891,0,0,0,0,0,65,0.669624173432661,0,0.0,0,0.0,0,0.0,0.06196,0.1624157907153529,0.3134280180761782,0.01942,0.3295279234804072,0.6704720765195927,24.48937630039127,4.3843151507761,0.3135401684816108,0.2315594822272447,0.2266283131292377,0.2282720361619067,11.081057497143505,5.778586288784695,21.006121945508447,12386.96145770462,55.57383300375647,13.552476419667986,17.371607068227593,12.43075493972051,12.218994576140387,0.552496404355866,0.782608695652174,0.6847968545216252,0.5787578757875788,0.1078875793291024,0.7228826151560178,0.9175,0.8423529411764706,0.754325259515571,0.1293103448275862,0.4873615450156205,0.7083906464924347,0.6239782016348774,0.5170316301703163,0.1021814006888633,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023414218816517,0.0044640592502409,0.0066833920754065,0.0094152575977875,0.0117041198501872,0.0140628343744586,0.0164294096637583,0.0188314873094372,0.0209343728896801,0.0230904769709883,0.0249879421634324,0.0270992680319105,0.0292890907405691,0.0314878607231997,0.0334304427777433,0.0357959660978361,0.0378618230073816,0.0399571961393411,0.042082248828735,0.0441624577367784,0.059172340225269,0.073813266268469,0.0865328068554146,0.099222097074706,0.1111744162736471,0.1265186470812344,0.1411980764535408,0.1548418024928092,0.1676982777973766,0.1806394830898689,0.1955005551543113,0.2050385036120828,0.2138416141290737,0.2227515661278311,0.2308251785241999,0.2405077336173801,0.2496786668305931,0.258050341393064,0.2653545901844255,0.2723102155038937,0.2796088835339504,0.286154206428195,0.2923747379889392,0.2986506278662152,0.3044578855772858,0.3101680256980479,0.3155636409259143,0.3206794098519529,0.3250924664200895,0.3282383145413159,0.3274272894366958,0.3257709738034707,0.3245242979415718,0.3237352616599872,0.3229818301258603,0.3204076291929003,0.3186729132804283,0.3180773491625192,0.3187936792095569,0.3204325452517183,0.3205322044148775,0.3224873319235526,0.3229160063391442,0.3240811724915445,0.3260880124344278,0.3277124940717711,0.3292030818767249,0.3325529895602657,0.3359776180189113,0.3386677335467093,0.3423724163160783,0.343445633083187,0.3449661059502887,0.347285757853004,0.346600018862586,0.3477286135693215,0.3505676587910402,0.3587489779231398,0.3640387275242047,0.3612828438948995,0.0,2.186158781718143,59.11141182225192,179.37550564436378,267.5429919064499,fqhc4_implementation,48 -100000,95753,44269,418.5665201090305,6127,62.65077856568463,4776,49.324825331843385,1923,19.72784142533393,77.39103701009569,79.7271163304464,66.2329145052769,68.08128946636515,77.14902118932588,79.4870566350908,66.1257788730329,67.97757001486166,0.242015820769808,240.05969535561175,0.1071356322439953,103.71945150349404,123.73548,91.9976714269036,129223.6065710735,96078.10870354308,244.71117,174.08022562208134,255167.7440915689,181404.05587509676,260.20173,143.8369710966018,268975.4159138617,147976.98175985657,3230.43331,1726.0769241420592,3338184.777500444,1767104.6172360734,863.83404,444.7116826512189,892177.7385564944,454465.7531891623,1689.55314,843.627956598909,1734593.4017733126,853794.089960817,0.38099,100000,0,562434,5873.800298685159,0,0.0,0,0.0,29126,303.62495169864127,0,0.0,32872,339.64471087067767,1322782,0,57960,0,0,0,0,0,55,0.5743945359414326,0,0.0,0,0.0,0,0.0,0.06127,0.160817869235413,0.3138566998531092,0.01923,0.3287949921752738,0.6712050078247261,24.440548380004856,4.347790185626118,0.3224455611390285,0.2307370184254606,0.2250837520938023,0.2217336683417085,10.974558417674286,5.647823056270399,20.818983752774542,12305.014511839176,54.45960023572189,13.234811680152593,17.41811666784544,11.812741294403152,11.99393059332071,0.5546482412060302,0.794010889292196,0.6941558441558442,0.5656279508970727,0.0986046511627907,0.7121771217712177,0.9341463414634148,0.8698795180722891,0.7111111111111111,0.1115384615384615,0.4922537269804151,0.7109826589595376,0.6293333333333333,0.5158428390367554,0.0944785276073619,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022476005345644,0.0045705599189257,0.0067247517521883,0.0090365421519154,0.0112319577149827,0.0135766408500157,0.01578293120313,0.0182294854531358,0.0201436203356589,0.0222329034699283,0.0242406242959261,0.0264442803216806,0.0285908012204768,0.0307174611015065,0.0329787014700727,0.0349226351560724,0.0369316123422798,0.0389002966005019,0.0409041309431021,0.0429461272446981,0.057946656923639,0.0712133260787678,0.0844619758500225,0.0965085708276369,0.1081140928981916,0.1231800543472514,0.138723602846809,0.1532740311974633,0.1661719167111585,0.1787770594100807,0.1943831235260545,0.2041427798810167,0.2134517545766839,0.2227482451728586,0.2306617371976849,0.2402300251520758,0.2490880085676993,0.2573617078712348,0.2653049651824801,0.2722288356760222,0.2798075477371823,0.2858629560336763,0.2917401232888058,0.2969227267826982,0.3029110649615623,0.3080440221343094,0.3122817557165922,0.317906651405316,0.3213966791339347,0.3258769498772666,0.3253643293914823,0.3240176594369335,0.323269731746814,0.3218810423941589,0.3210938426859651,0.3191850334729312,0.3183184133109796,0.3187054485866448,0.3196000953775931,0.3207184434911084,0.321870444436138,0.3221120681159706,0.3225792970872163,0.3240164939262231,0.3247427614261785,0.3261811483278416,0.3268166728144596,0.3306856712294361,0.3330298361115002,0.3346234350934007,0.3367444835305404,0.3397872340425532,0.3420571356498707,0.3436902119843881,0.3473264317599012,0.3541916886860437,0.3604812586765386,0.3654001616814875,0.3675450762829403,0.3661586557248925,0.0,2.1874086116180016,59.46993573113332,175.23295156863767,255.84299655044893,fqhc4_implementation,49 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-100000,95663,44199,417.7895320029688,6100,62.46929324817328,4798,49.41304370550788,1971,20.018188850443742,77.30933613681017,79.6949923005426,66.16754487630577,68.0564977029007,77.06005668292114,79.45236669469742,66.05908715028511,67.95468339996978,0.2492794538890308,242.625605845177,0.10845772602066,101.81430293091864,123.39998,91.74187891733814,128994.24019735948,95900.88008669822,247.53015,175.52104148471872,258184.8781660621,182911.1479722764,258.52069,142.63575124172226,267411.00529985473,146636.50840936237,3254.42225,1722.0994588280937,3354217.889884281,1752425.3565412897,921.48296,473.2115425012507,947102.1398032678,478507.785142899,1735.67869,852.7495478225251,1765975.9154532056,847826.4405119151,0.37989,100000,0,560909,5863.374554425431,0,0.0,0,0.0,29421,306.7643707598549,0,0.0,32746,338.4589653261972,1318346,0,57879,0,0,0,0,0,57,0.5958416524675162,0,0.0,0,0.0,0,0.0,0.061,0.1605727973887178,0.3231147540983606,0.01971,0.3374357376538401,0.6625642623461598,24.77569018130772,4.351445487318098,0.3092955398082534,0.2363484785327219,0.2365568987077949,0.2177990829512296,11.349820974336607,6.005009936232099,21.17986975278656,12315.069812114907,54.71268721752166,13.681554796964363,16.83919492400631,11.66972191644515,12.52221558010585,0.5623176323468112,0.798941798941799,0.717654986522911,0.5626794258373206,0.1224669603524229,0.7330350484712901,0.937354988399072,0.8772845953002611,0.7345454545454545,0.1626984126984127,0.4960948799537171,0.7140825035561877,0.662125340599455,0.5012987012987012,0.1109852774631936,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0020451761180127,0.0045088860518369,0.0066245320726771,0.0089275739140149,0.0113701082092588,0.0134489885261089,0.0156562155991356,0.0177410299596794,0.0200134922419608,0.0225018171394641,0.0243089730971128,0.026711716800345,0.0289061937435063,0.0309382471761892,0.0328977249267104,0.0350173225089198,0.0371191709844559,0.0391379274546851,0.0413788799201131,0.043444724718047,0.0583030379006309,0.0728032333724242,0.0859949828387895,0.0986075589656152,0.1109575164088386,0.1251891594442151,0.1401261039402173,0.1538461538461538,0.1667112199399065,0.1797665954500069,0.1944255755027225,0.2041267501842299,0.2129838437319562,0.22261046728153,0.2305073166431593,0.2399139202875239,0.2489131770990489,0.2576129832074834,0.264798145117294,0.2725019791415689,0.2792216075798165,0.2860474655728098,0.2925709812851348,0.2989469133875286,0.3050091950943258,0.3096673006150122,0.3145278571786771,0.3193322288772779,0.3224329966417281,0.3253659954547857,0.3250300079571662,0.323688595706003,0.3224090742360543,0.3217057631045468,0.3207210157331467,0.3182550520937227,0.3160281618673094,0.3171689617773688,0.3174367126472147,0.3179349767774205,0.3185101791912937,0.3187419641974087,0.3192029898379104,0.3209284610041897,0.3228714685179828,0.3231572080887149,0.3254549078793746,0.3289651488011061,0.3318277310924369,0.3338744160266054,0.3368085590712497,0.3384060660692508,0.3369894099848714,0.3408003644923684,0.3442853131142937,0.3442507068803016,0.3446293494704992,0.3489353153877059,0.3593109105824446,0.3667041619797525,0.0,2.8124157654286384,58.48274411368534,176.34428869396265,259.3096055986675,fqhc4_implementation,55 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-100000,95744,44200,417.9374164438503,6167,63.25200534759358,4796,49.50701871657754,1889,19.301470588235293,77.31606126737037,79.66706670325321,66.1766861243737,68.04009982691488,77.07415273921167,79.42932932962962,66.07085596780175,67.93941349456642,0.241908528158703,237.73737362358816,0.1058301565719546,100.68633234845947,123.17932,91.63014601800371,128654.87132352944,95703.27750877728,246.47178,174.54171031421623,256983.602105615,181856.1061938255,257.43121,141.41155117259925,266326.3076537433,145570.27593757506,3175.40947,1679.956522263334,3278393.6643549465,1716465.034115279,856.63885,441.0996798150244,883866.6130514706,449855.9490046633,1653.27673,811.8161711113784,1691469.9093415774,815779.0152017699,0.38047,100000,0,559906,5847.948696524064,0,0.0,0,0.0,29295,305.355949197861,0,0.0,32516,336.1672794117647,1320958,0,57925,0,0,0,0,0,67,0.6997827540106952,0,0.0,0,0.0,0,0.0,0.06167,0.1620889951901595,0.3063077671477217,0.01889,0.3244162672027215,0.6755837327972785,24.74331033798123,4.314334441559461,0.3331943286071726,0.231651376146789,0.2116346955796497,0.2235195996663886,11.196427611766374,5.934739698007598,20.221366264629893,12322.42937321316,54.47379997251443,13.301413164355951,18.002165606140856,11.950901745310018,11.219319456707606,0.5560884070058382,0.7857785778577858,0.6758448060075094,0.5708955223880597,0.1004926108374384,0.7188940092165899,0.9202898550724636,0.8518518518518519,0.7429718875502008,0.1068376068376068,0.4954207212364053,0.7058823529411765,0.6160938809723386,0.5188335358444714,0.0985915492957746,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022479191559164,0.004377875514299,0.0068375721546468,0.0090184329457167,0.0113858165256994,0.0136180433986076,0.0157377583887144,0.0177700206177149,0.0195916114790286,0.0219511446319473,0.0241733017717523,0.0262077740836514,0.0282842401693765,0.0303020942731821,0.0324982724656813,0.0346153448614455,0.0365841030526446,0.0386934099799736,0.0408804050611854,0.0428958333333333,0.0576794588048607,0.0715391859370095,0.0851847189879791,0.0980513812793791,0.1105649032121947,0.1257657352645556,0.1403810433582762,0.1540280322072168,0.1671530739873641,0.1798045952329826,0.1940736267765101,0.2034311336387562,0.2137180185084376,0.2221334092501752,0.2314353708518796,0.2410802417789607,0.2506568282184582,0.2588359931475971,0.2655207303070609,0.2725268669054836,0.2792685189480031,0.2851900055108047,0.2910721275308686,0.297577563625003,0.3031203204324377,0.3076742577681173,0.3136539690896101,0.3183561155203384,0.3211605024695679,0.3242954119231886,0.3240482447274442,0.3233163476105219,0.3228442991418063,0.3219361274559412,0.3209204024528189,0.3192599984647271,0.3178504643275966,0.3194805194805195,0.3195833974654969,0.3200157097972008,0.3220389748965724,0.3227369416213661,0.3236418321949997,0.3247039935781657,0.3254892544122943,0.3267610776412905,0.3283075870717665,0.3319231612923443,0.3353643590012956,0.3386821305159471,0.3436874658904857,0.3475531914893617,0.3485202246481984,0.3494960293219303,0.3524390243902439,0.3535918173168411,0.3558253919458961,0.3645683822021734,0.3723640399556049,0.3809897879025923,0.0,2.232471797369854,57.20526534721863,175.03518566616032,266.21706514750406,fqhc4_implementation,76 -100000,95792,44087,416.89285117755134,6078,62.35385000835143,4760,49.14815433439118,1862,19.156088191080677,77.39095688547141,79.73016183088085,66.22920496418115,68.08385478236636,77.15267159808955,79.4910453436735,66.1252696231147,67.9821349199368,0.2382852873818564,239.1164872073404,0.103935341066446,101.71986242956166,123.1967,91.6817975368407,128608.54768665442,95709.24245953806,246.16933,174.5074356368772,256583.6708702188,181773.7761367099,258.79854,142.6398558613058,267561.40387506265,146723.55939783584,3177.84479,1681.2191419868168,3285535.6919158176,1723165.5065003503,861.55282,441.5141321978324,890886.0343243695,452404.56179099466,1633.99682,803.5759747874071,1682126.3779856355,816630.5380146548,0.37855,100000,0,559985,5845.8430766661095,0,0.0,0,0.0,29232,304.59746116585933,0,0.0,32700,337.8883414063805,1326940,0,58108,0,0,0,0,0,61,0.6263571070653081,0,0.0,0,0.0,0,0.0,0.06078,0.1605600316999075,0.3063507732806844,0.01862,0.3369445752865442,0.6630554247134558,24.62586302588601,4.408144058477292,0.3178571428571428,0.2331932773109243,0.2115546218487395,0.2373949579831932,11.349717497518954,5.886418398849492,19.9574564603345,12246.776519148603,54.07985857436452,13.21265937115756,17.112690437716708,12.629184447875378,11.125324317614872,0.5630252100840336,0.7792792792792793,0.6893588896232651,0.5823008849557522,0.1132075471698113,0.7315384615384616,0.9236453201970444,0.8647214854111406,0.7403508771929824,0.168103448275862,0.4997109826589595,0.6960227272727273,0.6311619718309859,0.5289940828402366,0.0967741935483871,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023804459031006,0.0043492366025264,0.0067995453438337,0.0089709333631348,0.0110660197927155,0.0133477229456622,0.0158545662170291,0.0178775626888834,0.0203042571463624,0.0224069278249209,0.0246042811449192,0.0267975399652966,0.0287171367174246,0.0304456643767187,0.032550605616656,0.0346523909426318,0.0366573470021745,0.0385425420440515,0.0405055660073381,0.042548980803483,0.0574749825216783,0.0711178500470563,0.0847859126880142,0.097211858795834,0.1093056828839081,0.1249881099590982,0.1391000159007791,0.1528464622616427,0.1655887124316939,0.1781976713047763,0.1927608431336683,0.2020988014568405,0.2109195964071986,0.2202066314271984,0.2286072166307739,0.2378755186721991,0.2467682981189266,0.255777116216368,0.2631209209572154,0.27078922976576,0.2781084235707434,0.2847928205847297,0.2904255696531826,0.296475069169132,0.3022776085716712,0.3073987443062907,0.3128523041157869,0.3173139220244674,0.3211513583441138,0.3244379431222161,0.3239499132493174,0.3226298433635614,0.3210455198040706,0.3206906516399364,0.3201384350305983,0.3179626142470032,0.3160160825656124,0.3168162501845866,0.3173027729458713,0.3177556767547143,0.3186794708915627,0.3196426111428178,0.3202186248331108,0.3212393714107643,0.3224862011039117,0.3230945738051159,0.3241271198517885,0.3271368460717201,0.329727451531329,0.3335853260653324,0.3370206152580335,0.3389668367346938,0.3418619379354021,0.3443086325439267,0.3481481481481481,0.3533096926713948,0.3516383495145631,0.3522884882108183,0.3469333333333333,0.3511111111111111,0.0,2.11110234318953,57.13550416457413,176.58512670763417,259.2911410303089,fqhc4_implementation,77 -100000,95625,44361,420.05751633986927,6209,63.74901960784314,4904,50.645751633986926,1914,19.607843137254903,77.2981730373493,79.74318771355334,66.15422193859041,68.09657406868254,77.05627826485194,79.50263701012261,66.04914932121254,67.99476648227139,0.2418947724973605,240.5507034307277,0.1050726173778713,101.80758641115516,123.61624,91.97428680244528,129271.88496732026,96182.26070843951,248.24977,176.11338669267357,259158.6091503268,183721.8684367828,265.51274,146.69799522661197,274792.61699346406,151012.79377210516,3293.90942,1741.1851191389242,3407948.4967320263,1784184.521975347,916.81987,468.3708928849802,947504.3137254902,478538.0631476917,1679.73239,821.2662928042432,1723675.440522876,828719.3075164758,0.38097,100000,0,561892,5875.99477124183,0,0.0,0,0.0,29501,307.8692810457516,0,0.0,33577,347.2313725490196,1318200,0,57853,0,0,0,0,0,63,0.6588235294117647,0,0.0,0,0.0,0,0.0,0.06209,0.1629787122345591,0.3082622000322113,0.01914,0.335686876438987,0.664313123561013,24.6497139228055,4.337710131279088,0.324836867862969,0.2340946166394779,0.2169657422512235,0.2241027732463295,11.172790196894924,5.753668643076315,20.480814289403668,12372.549910968712,55.92492463623057,13.90577441067953,18.19297257397327,12.221603655214802,11.604573996362976,0.5681076672104405,0.789198606271777,0.6961707470182047,0.5814376706096451,0.1240601503759398,0.7350611951043916,0.9051918735891648,0.8508771929824561,0.740072202166065,0.1267605633802817,0.5021337126600285,0.7163120567375887,0.6341248900615655,0.5279805352798054,0.1233842538190364,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023015309743485,0.004465327744908,0.0064610508350603,0.0088782670599003,0.0113124936360859,0.0134789302501045,0.0157424044429924,0.0180626827223846,0.019927536231884,0.0221395406045324,0.0243757248570812,0.0265319339220181,0.028790609071719,0.0306889546574819,0.0326175647341947,0.0349818934299017,0.0369932730080744,0.0390271258256137,0.0409225261229757,0.0429445933403551,0.0574955318415084,0.0723817903756311,0.0848628669830736,0.0978867162011408,0.1101975767298518,0.1256521233028921,0.1406128926111093,0.154982060536374,0.1684509690792144,0.1819595812237192,0.197347440096535,0.2069700972219214,0.2156389342033714,0.224541138894358,0.2330146225532804,0.242036241194453,0.2505325615373462,0.2586778811015033,0.2660459947382745,0.2729593296780028,0.2810012955765315,0.2879794200187091,0.2939639682239455,0.2999964063679161,0.3055039296429916,0.3103571516600527,0.314580596734847,0.3195518364024824,0.3228215982497702,0.3271146411937778,0.3266592160717411,0.3250392227023754,0.3229917755745831,0.3230153107695866,0.3217651080526738,0.3197216486961841,0.3184681120430447,0.3195417767638804,0.3203083602550297,0.3205906510016784,0.3218063694744528,0.3216341982806215,0.3224234565835703,0.322910617769241,0.322809464268539,0.3243757990033656,0.3252627681089241,0.3295836606441477,0.3330050647158131,0.3362884868815143,0.3381962864721485,0.3416394845195444,0.3451547179421877,0.3482238966630785,0.3481955317930112,0.3519593613933237,0.3528131799813491,0.3511264461132535,0.3519289480988065,0.3512476007677543,0.0,2.5174220693944527,60.854340201042255,176.49087991667392,267.2649741788126,fqhc4_implementation,78 -100000,95689,44030,416.26519244636273,6177,63.2988117756482,4853,50.16250561715558,1912,19.57382771269425,77.29536313439843,79.68018327408782,66.16424529425653,68.05401883046171,77.05594609167606,79.4407910371186,66.06071108786239,67.95271673849928,0.2394170427223656,239.3922369692234,0.1035342063941442,101.30209196243813,122.87902,91.37856346913593,128414.99022876192,95495.36881891952,245.71659,174.41305638991696,256363.3646500643,181850.5413649575,257.74314,142.35782903954043,266812.68484360795,146673.2095954943,3257.62536,1716.1367238071564,3366796.2461724966,1756346.6587034569,897.44926,458.6523456864867,926788.993510226,468223.3126968478,1683.89081,825.0145680343827,1725133.0560461497,833290.6510830127,0.37941,100000,0,558541,5837.045010398269,0,0.0,0,0.0,29204,304.6118153601773,0,0.0,32580,337.07113670327834,1323057,0,58013,0,0,0,0,0,64,0.668833408228741,0,0.0,2,0.0209010440071481,0,0.0,0.06177,0.1628054083972483,0.3095353731584911,0.01912,0.3359640978025379,0.6640359021974621,24.54051567374943,4.412509464408639,0.3152689058314444,0.2379971151864826,0.2233669894910364,0.2233669894910364,11.312113792609706,5.770019498811471,20.520809044911392,12289.781430820643,55.222631444999344,13.832986765099356,17.442725644034205,11.989454145008528,11.957464890857247,0.5567690088604986,0.78008658008658,0.6941176470588235,0.5470479704797048,0.1346863468634686,0.7375093214019388,0.9354066985645934,0.8672985781990521,0.7294117647058823,0.1869918699186991,0.487756264236902,0.6919945725915875,0.628158844765343,0.4909529553679131,0.1193317422434367,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0021163271092389,0.0042881472770771,0.0066576004221892,0.0089396371320018,0.0111881852763481,0.0134731910993431,0.0155297236667686,0.0177760080048192,0.0200181983621474,0.0222704606657587,0.0242262069531161,0.0263992853402334,0.0285405738969453,0.0305256217419075,0.0325337517030675,0.0346924214379517,0.0369614535961795,0.0391525933922213,0.0410799342721051,0.0430554687011443,0.0582035452769682,0.0721554503957452,0.0849688293696605,0.0974537037037037,0.1097415548918836,0.125345329452236,0.1395672301027775,0.1534323906907386,0.1666862659154809,0.1786906538143644,0.192789005658852,0.2020493046228499,0.211665559705149,0.2212576358023339,0.2300523271825943,0.2389476719682349,0.2480650457352826,0.2572962508582169,0.2649754147693076,0.2718140430948476,0.2786877649838982,0.2850083144014802,0.2914856080609067,0.2974259943386269,0.3035062977192044,0.3081621321488062,0.3128446806377218,0.316730377166157,0.3207774694639662,0.324969262701445,0.3242270195925082,0.3227051010003582,0.3210997532604864,0.3207277039436579,0.320362219710938,0.3180988604818797,0.3174849540703199,0.3192398035447363,0.3197602739726027,0.3196049665438151,0.3214319235606615,0.3221279632125585,0.3233582011137964,0.3244279946164199,0.3257692678692003,0.3272484416740873,0.3266685763391578,0.3299497201404041,0.3329086147094217,0.3372966459128339,0.340666911629616,0.3431816969761613,0.3468949396676985,0.3474748999773533,0.3473723443906075,0.3508462623413258,0.3521084786171956,0.3587408433973471,0.3618279569892473,0.3671552048102217,0.0,2.144713087549776,59.10740564679984,178.80918306165566,263.5354372655958,fqhc4_implementation,79 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-100000,95744,44259,418.7311998663101,5978,61.19443516042781,4678,48.15967580213904,1846,18.789689171122998,77.36446839131986,79.71547116254298,66.2118481571587,68.07531106728106,77.13386078593038,79.48881106289586,66.11130356607804,67.97927698650153,0.2306076053894798,226.66009964711972,0.1005445910806628,96.0340807795319,122.90256,91.46560002953704,128365.11948529413,95530.7346982966,245.89799,174.2924228156711,256299.6532419786,181511.3775439413,254.56376,140.43935257448484,262842.12065508025,144100.91736732455,3131.95674,1652.5556856223586,3223395.6174799465,1678266.934661554,848.98109,430.87130912316167,869522.883940508,432869.3761596913,1623.12569,793.8844040394982,1653786.482703877,793462.0699035097,0.38109,100000,0,558648,5834.77815842246,0,0.0,0,0.0,29299,305.28283756684493,0,0.0,32077,330.85101938502675,1327474,0,58076,0,0,0,0,0,65,0.6788937165775402,0,0.0,0,0.0,0,0.0,0.05978,0.1568658322181112,0.3087989294078287,0.01846,0.3272727272727272,0.6727272727272727,24.456525049679698,4.4269943799297184,0.3202223172295853,0.23492945703292,0.2244548952543822,0.2203933304831124,11.155047247677986,5.717437353768838,19.79204065879183,12325.648415639864,53.05770684993074,13.124793376271176,16.90867557934121,11.60268220153647,11.42155569278188,0.5585720393330483,0.7716105550500455,0.6895861148197597,0.600387972841901,0.1076190476190476,0.7298161470823341,0.891566265060241,0.8648648648648649,0.7142857142857143,0.165,0.4960606944849722,0.6988304093567251,0.6320921985815603,0.5607843137254902,0.0941176470588235,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0019448158502491,0.0041265335090743,0.0062310354275971,0.0083500096502544,0.0108592868254888,0.0131742379507645,0.015495183240736,0.0176699366087196,0.0198885993152434,0.0220038890594616,0.0241767702130712,0.0261993491227529,0.0284841691774553,0.0306708014382411,0.0327192031790266,0.0348680946080052,0.0369334948591308,0.0388799585169821,0.0408019039502811,0.0428877918723572,0.0573468471759757,0.071856725910893,0.0844571212852079,0.0970068442024033,0.1091415254505383,0.1248903033442941,0.1393984404010397,0.1532974929472507,0.1671243708793263,0.1797657607413286,0.1943047313379788,0.2041030524026444,0.2131915680071317,0.2219901357159261,0.2303042980447419,0.2393304511694934,0.24884437596302,0.2577349744605207,0.2657903392271835,0.2732162885984389,0.2802353403534728,0.2862018185643159,0.2930863263424207,0.2997880975469597,0.3049895696890312,0.3097255876311484,0.313859951535137,0.3192332106131776,0.3223971664210553,0.3266585041536659,0.3256419899000752,0.3250390935776796,0.3242106743548273,0.322676558463115,0.3223262032085561,0.3207720447553304,0.3186390813324475,0.3191213622494176,0.3198457916823036,0.3210420269957028,0.3220826792255363,0.3218853623874941,0.3234584984380569,0.3242935074226435,0.3255919963532545,0.3256273566506306,0.3270054765755796,0.3307456332561197,0.3346963025092612,0.3380521849472599,0.3372681281618887,0.3388050951340404,0.3418700475435816,0.3442159186482147,0.3474544072948328,0.348633748801534,0.3507869721053451,0.3535831960461285,0.3583125173466556,0.3547140649149923,0.0,2.653456513725528,54.26945347047042,175.91996085898947,255.80777426209687,fqhc4_implementation,83 -100000,95778,44389,419.584873352962,6217,63.74115141264173,4879,50.33515003445467,1979,20.349140721251224,77.41058500195152,79.74617393704202,66.23311286366996,68.08186353330949,77.16549083995719,79.49842474553755,66.12846655682772,67.97785279871485,0.2450941619943307,247.7491915044681,0.1046463068422411,104.01073459463817,122.13718,90.91012595310036,127521.12176073836,94917.54468990827,247.46659,174.4381231299652,257854.1731921736,181606.53086300116,255.69379,140.7546496060424,263716.2918415502,144238.82728540353,3299.46022,1721.0776871928326,3408978.679863852,1761019.3021287068,886.12738,451.5344351667901,914245.0875984046,460494.8058706488,1746.30871,846.5532664904422,1796968.2077303764,862220.2946709772,0.38217,100000,0,555169,5796.414625488108,0,0.0,0,0.0,29335,305.66518407149863,0,0.0,32276,332.6233581824636,1331970,0,58428,0,0,0,0,0,69,0.7099751508697195,0,0.0,1,0.0104408110422017,0,0.0,0.06217,0.1626762958892639,0.318320733472736,0.01979,0.3259304640833205,0.6740695359166794,24.58143621633728,4.479982058029642,0.3131789301086288,0.229965156794425,0.2283254765320762,0.2285304365648698,11.05859342942424,5.481422564363,21.163165152987496,12378.96075089082,55.22816422359221,13.403818039698177,17.26268109262053,12.369159462824673,12.192505628448828,0.5501127280180365,0.7655971479500892,0.706151832460733,0.5560538116591929,0.1131059245960502,0.7102584181675803,0.91,0.8772378516624041,0.6747967479674797,0.1416666666666666,0.4933370349805663,0.685595567867036,0.6473175021987687,0.522439585730725,0.1052631578947368,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.002268124746861,0.0045807870440748,0.0066849937613487,0.0091001421897217,0.011447277459233,0.0136201227643352,0.0159621637599763,0.0183697837468235,0.0202638490072451,0.0221540035814786,0.024447723267347,0.0264343400137507,0.0285617381652243,0.0307684389314941,0.0327084493390253,0.034789075734413,0.0369212939009499,0.038858008047455,0.0410852149336547,0.0430427720628045,0.0577603389441389,0.071646660253461,0.0853704557843096,0.0980482831828644,0.1107527221747883,0.1263112257846206,0.1410267288926601,0.1544691221386231,0.1678338101541483,0.180037713208194,0.1947730428511458,0.2055807916937053,0.2148175523646996,0.2241654460791815,0.2316186579558078,0.2409019425432476,0.249511996519838,0.258701935512894,0.2659322206968538,0.2733770101250744,0.2805351897680228,0.2875083235008936,0.2937651439040246,0.3008496888463379,0.3064500473197602,0.3113244707040866,0.3161636988441112,0.3211798495323302,0.3244215539106579,0.3284473326918261,0.3276019804111506,0.3263296848358176,0.3252215818619922,0.3241016449365442,0.3235587294502715,0.3208876202753096,0.3175474211761721,0.3182864281956865,0.3192143467122117,0.3198065563823902,0.3215436493068565,0.3222353636901242,0.3238053448672141,0.3243514308638673,0.3262173985800005,0.3273983592557128,0.3284914938111117,0.3328973185088293,0.3349094322567187,0.3361149380043298,0.3412970824677084,0.3421468450437164,0.3408052094421138,0.3413990652796623,0.3433583959899749,0.3435867672663958,0.3448792922477133,0.3527546571541815,0.3566414686825054,0.3571700266260936,0.0,2.3542759278091534,56.11450901213884,184.8430210004989,267.4637166901412,fqhc4_implementation,84 -100000,95763,44349,419.9847540281737,6109,62.64423629167841,4879,50.40568904482942,1944,19.976400071008637,77.29075226531792,79.63010124584487,66.17497297535141,68.02874796983481,77.05067297914005,79.38894577024664,66.07201772912123,67.92715795521472,0.240079286177874,241.1554755982337,0.1029552462301808,101.59001462008632,123.45652,91.79225914706852,128918.80997880184,95853.57512511988,250.05454,176.94373473856848,260728.24577341985,184382.6788410644,262.1819,144.42201509385788,270814.75099986425,148379.8624046402,3266.07689,1725.4914287662066,3377711.443877071,1768963.324839663,906.37328,465.5536626887006,936477.783695164,476154.258626715,1714.99733,832.9907709239578,1763852.4900013574,846543.969879895,0.38138,100000,0,561166,5859.945908127355,0,0.0,0,0.0,29613,308.6787172498773,0,0.0,33200,342.80463226924803,1318750,0,57913,0,0,0,0,0,72,0.7414136984012614,0,0.0,0,0.0,0,0.0,0.06109,0.1601814463264985,0.3182190211163856,0.01944,0.3286494925839188,0.6713505074160812,24.39016776128372,4.301102767220001,0.3283459725353556,0.2303750768600123,0.2232014757122361,0.2180774748923959,11.40268051011524,6.0387067426730106,20.69610435316541,12374.337953368338,55.63216728662148,13.56919204955,18.105482374782763,11.898143844597945,12.059349017690778,0.5697888911662226,0.8078291814946619,0.6978776529338327,0.5958646616541353,0.1101928374655647,0.7484615384615385,0.9508599508599508,0.863961813842482,0.758893280632411,0.1447963800904977,0.504889633975971,0.7266387726638772,0.6390532544378699,0.5450061652281134,0.1013824884792626,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.002106115836371,0.0044695794946638,0.006857583411952,0.0089374581056651,0.0112346984423929,0.013226220294459,0.0151067256528918,0.0173184471567947,0.0197348922297055,0.0219658740800638,0.0238646847770374,0.0259750926581862,0.0281882783656763,0.0302034509399948,0.0322171198596563,0.0342796316773973,0.0364853954913366,0.0383318986527831,0.0401962006900278,0.0422529343762042,0.0562258636885502,0.0708980206720508,0.0845219616562486,0.0974963181148748,0.110411525237824,0.1259180088467481,0.1402683708783626,0.1539559456350389,0.1675237616670052,0.1802919708029197,0.1951947743979994,0.2047920140317446,0.2135680306543439,0.2236133607669745,0.2319178926966787,0.2415368409380717,0.251010879521033,0.2589181154850914,0.2663137326183768,0.2734100003439696,0.2811269171956814,0.2874084490537294,0.2941371668306095,0.3013365006238602,0.3063375145857643,0.3117345555801976,0.3170081813405389,0.3216978852732104,0.3251987260816654,0.3291139240506329,0.3284645961059085,0.3265789654934913,0.3255692412000678,0.3243936736202722,0.3236521946564885,0.3218973838728519,0.3199485158583868,0.3206894848619548,0.3214604351108366,0.3225922076060074,0.3238340507923379,0.3249365280863218,0.3253759596172048,0.3254780500942634,0.32615533510767,0.327479095127002,0.3269626916914626,0.3288306769764873,0.3310249796841324,0.3345171588188348,0.338092177745134,0.3417519181585677,0.3429593662151802,0.3427335239125396,0.3453258061429528,0.3423728813559322,0.3457289559670141,0.3479771148344912,0.3517951572502087,0.3514890282131661,0.0,2.10570516779022,57.17661813441046,188.3535087635299,264.74167627026134,fqhc4_implementation,85 -100000,95709,44301,419.89781525248407,6129,62.87809923831615,4835,50.06843661515636,1918,19.77870419709745,77.28742900870407,79.67928992727953,66.16259666366798,68.06085596836049,77.04018822102687,79.42872570671327,66.0575247295869,67.95613930383624,0.2472407876771996,250.56422056626104,0.1050719340810815,104.716664524247,123.18482,91.64532528998636,128707.66594573132,95754.135232827,247.93926,175.7496341767535,258693.0800656156,183266.9176114613,260.27309,143.50103196961982,269751.16237762384,148116.12431223367,3214.70952,1694.9902233440962,3331319.938563771,1743465.8217556295,889.244,453.34852144428896,921851.2992508542,466412.9616277352,1682.9139,816.1431469882423,1736833.0564523712,833864.067141399,0.38095,100000,0,559931,5850.348452078697,0,0.0,0,0.0,29444,307.13934948646414,0,0.0,32965,341.45169210837014,1320158,0,57961,0,0,0,0,0,60,0.6269002915086356,0,0.0,0,0.0,0,0.0,0.06129,0.1608872555453471,0.3129384891499429,0.01918,0.3256752561316361,0.6743247438683638,24.574922180117987,4.335740283383227,0.324095139607032,0.2361944157187177,0.2179937952430196,0.2217166494312306,11.21045469514903,5.878962592153258,20.56926514028508,12330.583095475498,55.15594476370692,13.888812400604175,17.727556706297996,11.962167945133327,11.57740771167143,0.56153050672182,0.7828371278458844,0.6879387364390556,0.5680970149253731,0.127134724857685,0.7604245640636846,0.9305555555555556,0.8621553884711779,0.7927272727272727,0.1830985915492957,0.4869169510807736,0.6929577464788732,0.6284246575342466,0.4905897114178168,0.1129607609988109,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023919080534327,0.004382494369712,0.0065194211728865,0.0087708600117893,0.0110883917762789,0.0132297225730231,0.0153344208809135,0.0174686309943132,0.0195166336107305,0.0216569901391576,0.02374334622209,0.0259941664612603,0.0280592040977957,0.0299880501071369,0.0322161225079456,0.0342977086607659,0.0363028099721385,0.0384743124026984,0.0403382672644247,0.0420493042163965,0.0571401714936238,0.070532209953425,0.0834565880983101,0.0960933803039066,0.108347217242761,0.1243906307830592,0.1390014210872378,0.1523839931885909,0.1649430567722911,0.1785289038112912,0.1936428948417186,0.2036161395384066,0.2130175583647005,0.2221614645989632,0.2300162952523562,0.2400399068839374,0.2494305747845116,0.258292985024209,0.2662207129958774,0.2727908309455587,0.2801667245571378,0.286274280365083,0.291886195995785,0.2980667754005565,0.3034018073241629,0.3092623405435385,0.3144211882748871,0.3188619706840391,0.3233344553481266,0.3280161494616846,0.3274093222392762,0.3252078401145185,0.3240991372018271,0.3230479774223894,0.3228164736011435,0.3207222963747104,0.3193610872947826,0.3208520031628887,0.3215711129001867,0.32259624858919,0.3235481932236496,0.324699811451821,0.3256387034267781,0.32754085830542,0.3285697013662193,0.3300790451761503,0.3331617920347657,0.3357285302776107,0.3389133210384452,0.3426290024877618,0.3473122729571894,0.3498655190962883,0.3545990263899564,0.3558548099992261,0.3611402421584517,0.3643680922633349,0.3600309837335398,0.3637474541751527,0.3658536585365853,0.3684409211023027,0.0,1.693395022704294,58.51316510030501,183.5706894966656,260.6823859612141,fqhc4_implementation,86 -100000,95749,44338,420.0148304420934,6130,62.851831350719074,4797,49.5984292264149,1858,19.04980730869252,77.3358889068281,79.69530742381983,66.19428613524023,68.06580803262689,77.09489982227058,79.45641082932194,66.08937158315635,67.96438951196684,0.2409890845575262,238.8965944978878,0.1049145520838834,101.4185206600473,122.67904,91.3193570055442,128125.4321193955,95373.46291401912,247.74594,175.4748523041948,258340.964396495,182861.2333331887,260.34866,143.35278481042587,269658.8058360923,147821.41999349065,3183.82207,1689.3013378998903,3293024.418009588,1732150.9549968028,892.48226,462.499091761943,922951.1953127448,473910.7218341132,1630.94186,804.2678357005778,1673655.505540528,812761.2664142629,0.38094,100000,0,557632,5823.8832781543415,0,0.0,0,0.0,29411,306.61416829418584,0,0.0,32986,341.497039133568,1325408,0,58119,0,0,0,0,0,55,0.5744185317862328,0,0.0,1,0.0104439733052042,0,0.0,0.0613,0.1609177298262193,0.3030995106035889,0.01858,0.3273549594510293,0.6726450405489707,24.52812000062906,4.4078223077199885,0.3304148426099645,0.2301438398999374,0.2143006045445069,0.225140712945591,11.42361218852522,5.941330747121498,19.999233266422568,12312.38060268162,54.5442083702859,13.29207717114741,17.82654607696613,11.999918677089152,11.42566644508319,0.5751511361267458,0.7952898550724637,0.7085173501577287,0.5787037037037037,0.1293774319066148,0.7225656877897991,0.9183673469387756,0.8571428571428571,0.73828125,0.1781376518218623,0.5206965458178704,0.7275280898876404,0.6585160202360877,0.529126213592233,0.1139564660691421,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022897437715929,0.0044821222138844,0.0068315856790474,0.0089128733599601,0.0109890109890109,0.0130404661966665,0.0152088539807211,0.0174945871971894,0.0196425284770649,0.0216770256294733,0.0238043979701676,0.0257705497032793,0.0278643182495861,0.0299042323138708,0.032149266662541,0.0341037058464971,0.0362330093067072,0.0381200340227786,0.0403987899075797,0.0423568139675396,0.0568141482053744,0.0705772792432692,0.083794781441396,0.0966158180805096,0.1087094053142134,0.1247024722571909,0.1390580894369336,0.1533352492256602,0.1670618391541172,0.1797208344947361,0.1949523009669014,0.2045695493195439,0.2142942603247805,0.2229050034989503,0.2309917719012628,0.2403250988251708,0.2504603229514234,0.259343454236487,0.266398701048018,0.2729679245499238,0.2799073806078148,0.2859935158417116,0.292567055255426,0.2981499022793492,0.3036252674576931,0.3084568525414951,0.3129301929767477,0.317697336623337,0.3219443329145566,0.326495591108295,0.3250127904784985,0.3233967660323397,0.3220553671203186,0.3219984116670276,0.3209192465387129,0.3191811862694062,0.3183018420428492,0.3181303998557306,0.3187973258748891,0.3205157889112508,0.3216241984632929,0.3233537654965804,0.3250674305308716,0.3253135970306106,0.3272021599730003,0.3284639105210892,0.3294945982155582,0.3325792566060263,0.3353093868387821,0.338883602917856,0.341034655951783,0.3419694689314126,0.3440261237034191,0.3463565891472868,0.345249474287899,0.3520076941572493,0.356072432094911,0.3581596864039612,0.3588879528222409,0.3567877629063097,0.0,1.83098339766383,57.15610558560863,180.4834404084974,261.68495391677567,fqhc4_implementation,87 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-100000,95858,44436,420.5282814162616,6122,62.74906632727576,4837,50.02190740470279,1956,20.113083936656302,77.40634548897815,79.71388075867637,66.24077102421039,68.07122045395417,77.16211093336823,79.46895775784778,66.1356402249143,67.96800416200402,0.2442345556099212,244.9230008285923,0.1051307992960914,103.21629195014737,123.42264,91.83414195478274,128755.70114127146,95802.27206365952,248.37194,176.0737116406654,258760.0304617246,183337.81389207512,259.43889,143.00146036298287,268739.6357111561,147605.89918725233,3247.91008,1714.240746027603,3359509.628825972,1759570.8297978302,899.38731,459.0500553818048,930766.508794258,471413.4398060213,1726.43249,836.9196991576875,1776677.721212627,851161.1240167072,0.38079,100000,0,561012,5852.531870057794,0,0.0,0,0.0,29517,307.4547768574349,0,0.0,32828,339.86730372008594,1323156,0,57997,0,0,0,0,0,54,0.5633332637860168,0,0.0,1,0.0104320974775188,0,0.0,0.06122,0.1607710286509624,0.3195034302515517,0.01956,0.3267249453637215,0.6732750546362785,24.383590956976946,4.407563622978458,0.3171387223485631,0.2363034939011784,0.228447384742609,0.2181103990076493,11.216098462387894,5.722544417238007,20.73000671736196,12264.47669108876,54.94707935651934,13.83186757859218,17.166026286373757,11.785140964236692,12.164044527316696,0.5501343808145545,0.7926509186351706,0.6616688396349413,0.5753554502369668,0.1203619909502262,0.7350689127105666,0.916289592760181,0.8688946015424165,0.7387755102040816,0.1565217391304348,0.4817332200509771,0.7146932952924394,0.5912663755458515,0.5259259259259259,0.1108571428571428,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022987574557717,0.0044485879026782,0.0066240616757963,0.0089561332250203,0.0111922091652096,0.0134136660628142,0.015855385838165,0.0179508113072762,0.0200742050553471,0.0220357197686914,0.0238671066385194,0.0261766668377559,0.0282401077380156,0.0303654355056272,0.0326430000618824,0.0347453249302613,0.0366908857562773,0.0383123885363527,0.040061089005018,0.0422530812791472,0.0571905308165606,0.0709469700929304,0.0846109510086455,0.0977608725347007,0.1094796713713924,0.1249286876413041,0.1399440393420383,0.1535206175701252,0.1666737794469102,0.1794501033600034,0.1944244275465975,0.2036508965219269,0.2123041509679801,0.2215005403517198,0.2293671720500988,0.2387686728070854,0.2483398698636242,0.2575103920907763,0.2639302834219145,0.2710315645013724,0.2774111528459982,0.2838892002989536,0.2909866578428012,0.297145318369984,0.3030435415756516,0.3085013362233525,0.3134977684989561,0.3173834578821615,0.3217345169388442,0.3253736856686763,0.3246623850493463,0.3227789774837352,0.3217036254839845,0.3210299065690479,0.3196574091941397,0.3184078079823769,0.3173327850443639,0.3173663496228271,0.3173630201307904,0.3174523839274558,0.3179191835815855,0.3186780586210988,0.3188341936296109,0.3204166200022399,0.3193789118921521,0.3204864456654774,0.3227440933674921,0.3258289374529012,0.3293098003438717,0.3346405228758169,0.3366192704311089,0.3389203193570559,0.3431188056705557,0.3463898780210622,0.3481343283582089,0.347077427667799,0.3474943904263276,0.347507911392405,0.3481640310908603,0.3448403860430586,0.0,1.6620501945286652,57.70523269191452,182.93403657728652,262.3492100573102,fqhc4_implementation,89 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-100000,95781,48123,459.0680823962999,4694,47.74433342729769,3836,39.47547008279304,1481,15.128261346196007,77.44562150151836,79.77677825484383,66.25752162197742,68.10235652581221,77.25003596942086,79.58354479869892,66.16987887537843,68.01820308111284,0.1955855320974961,193.2334561449096,0.0876427465989877,84.1534446993677,202.60196,150.76112702314026,211526.2525970704,157401.91376488056,368.16596,268.6740603522465,383968.85603616585,280094.49718863505,355.54653,198.1058023662497,368406.50024535134,204531.061911169,2504.1297,1380.5640780145895,2578255.9067038344,1405349.968648342,661.38941,357.94599934166894,680400.8519434961,363629.5958072483,1285.68543,646.9430348295538,1314038.3687787766,649453.0422591207,0.3801,100000,0,920918,9614.8296635032,0,0.0,0,0.0,44151,460.3835833829256,0,0.0,44486,460.6550359674674,814982,0,35756,0,0,0,0,0,97,1.012726950021403,0,0.0,0,0.0,0,0.0,0.04694,0.1234938174164693,0.3155091606305922,0.01481,0.3716741711011052,0.6283258288988948,22.40139474899516,3.948995558010636,0.3052659019812304,0.2935349322210636,0.1962982273201251,0.2049009384775808,11.384249916622164,6.301352465261855,15.951591946469636,11291.82724366464,44.33930040555407,13.92732062926587,13.385042891071237,8.758525472295071,8.26841141292189,0.6003649635036497,0.8161634103019538,0.7096498719043552,0.583969465648855,0.1248339973439575,0.7764887857695282,0.920388349514563,0.8710526315789474,0.7636363636363637,0.1741573033707865,0.5108139992135273,0.7283142389525368,0.6321112515802781,0.5141342756183745,0.1095652173913043,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022476688029644,0.0045805085175163,0.0067146769449234,0.0089661054812046,0.0112622227643268,0.0134840836929088,0.0158155934414201,0.0179150768226244,0.0200118497936501,0.0219566596410812,0.0241188524590163,0.0263228110504494,0.0285206273510246,0.0305216997447088,0.0322743630195605,0.0342811696293006,0.0363429399285973,0.0383650276850334,0.0402514416333316,0.0423755283926451,0.0569138778449112,0.0710401372069189,0.0839963520865436,0.0974379453120074,0.1095343447113358,0.1250766077051501,0.1393387921994004,0.1530040706139931,0.1663537644272822,0.1791988003427592,0.1941812315138478,0.200467006832137,0.2077840211283678,0.2154423100051387,0.2210961828365188,0.2285730113006869,0.2359833943397911,0.2425056783682281,0.2481650803734501,0.2536840056333512,0.2590224955494417,0.2637904252461429,0.2688086941113933,0.2738792588164973,0.2769924046952793,0.279398751290497,0.2829948446530439,0.2866373018190127,0.2887333040535303,0.2902432286665176,0.287227765261238,0.2824960947134753,0.2790172940549934,0.275572793219852,0.2726533869251684,0.2686530786338847,0.2654278251565597,0.266066271841809,0.2652790756945034,0.2651826888967719,0.2649571059046839,0.2653153418576788,0.2661226528997876,0.266977466977467,0.2689235450741727,0.270548827621747,0.2721780425436255,0.2776194311915236,0.2814576411960133,0.2841912051862845,0.2884020964924069,0.291527021365731,0.2964833520389076,0.2976002407282028,0.2995298239144464,0.304195395582564,0.3085551899491475,0.3156446540880503,0.3247773703509691,0.3246323529411765,0.0,2.26585658875372,56.35402509880412,132.54186391006223,184.83575485834845,fqhc3_implementation,39 -100000,95706,48660,463.8371679936472,4594,46.966752345725446,3677,37.84506718492048,1396,14.220634025035002,77.31966845828218,79.69829506646285,66.17605969217594,68.06067535754809,77.13636472218771,79.51876833980545,66.09410923231258,67.98346621061577,0.1833037360944729,179.5267266574001,0.0819504598633642,77.20914693231862,201.48018,150.0209131225512,210519.67483752323,156751.60713283508,364.65413,266.5746919191833,380583.3281090005,278103.4020011109,356.71407,198.06316538598463,370183.1860071469,204804.2643098432,2392.44529,1306.4556677566936,2463355.4322613003,1328641.1800270565,635.55106,335.28284858501183,653267.3186634067,339551.7490220176,1210.19714,607.6725305350052,1233305.821996531,606145.2788071481,0.38322,100000,0,915819,9569.07612897833,0,0.0,0,0.0,43721,456.22009069441833,0,0.0,44622,462.79230142310826,815601,0,35736,0,0,0,0,0,80,0.8358932564311538,0,0.0,0,0.0,0,0.0,0.04594,0.119878920724388,0.30387461906835,0.01396,0.3622704507512521,0.6377295492487479,22.8455347279271,4.005017076221711,0.299972803916236,0.3048680989937449,0.1952678814250747,0.1998912156649442,11.151147161185316,6.130705139855585,15.032985045472207,11376.475802923607,42.693315846730734,14.037202610986071,12.577563580517449,8.171115232400021,7.907434422827194,0.6004895295077509,0.8198037466547725,0.7017225747960109,0.5836734693877551,0.1197771587743732,0.7649536647009267,0.9064885496183206,0.8589743589743589,0.7593582887700535,0.1402439024390244,0.5220883534136547,0.7437185929648241,0.6396965865992414,0.5237226277372263,0.1137184115523465,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023193396465285,0.0046427231903009,0.0070939260161363,0.0094864711140001,0.0115823833880759,0.0136958403339952,0.0157550171316691,0.0178161212925621,0.0201206420611389,0.0220652229560231,0.0241786637135474,0.0261795698703859,0.0284012590779105,0.0305322273172239,0.0324667953229651,0.0345415822339853,0.0367039956904142,0.0390715827935558,0.0413217123601114,0.04351950299164,0.0585095827458352,0.0724601280924274,0.0861296717820691,0.0988032138650513,0.1109119095578077,0.1263710112430854,0.1419780592866085,0.1566103427348516,0.169519779444765,0.1819449809021072,0.1965881047061739,0.2027960668803604,0.2093610536627843,0.2165112103695918,0.2219812162117525,0.2296401410168289,0.2366326131859543,0.2442596010985547,0.2497615370639535,0.2552925525814812,0.2605255230901128,0.2648867029685579,0.2693551635489106,0.2732431200364692,0.2773887673231218,0.2802915387176736,0.2836471605216672,0.2870197141511715,0.2892442236539108,0.2912393556721415,0.287923069670972,0.2844577202086803,0.2805455365193868,0.2779991913590943,0.2758098518364559,0.2708183473882367,0.2680448216458837,0.2687448862706594,0.2680780816555762,0.267513095977981,0.268331780055918,0.2681026851578637,0.2703384179378177,0.2701566254338347,0.2714111369020555,0.2723927969944293,0.2732936845086378,0.2782193958664546,0.2834850907068881,0.2871964159396368,0.2878529041539291,0.2930899199665219,0.2956852001743353,0.3015849056603774,0.3037691949744067,0.3055294117647059,0.3104905660377358,0.3216050602885946,0.3225719666397632,0.3258003766478343,0.0,2.19848754962606,51.78643290691434,134.06953337160024,179.85374132795582,fqhc3_implementation,40 -100000,95694,48182,459.9765920538383,4621,47.014441866783706,3726,38.27826195999749,1361,13.804418249838024,77.34536576252451,79.72812562702623,66.18632157148963,68.07454577061478,77.16331829388297,79.55211354891156,66.10408875235807,67.99786712516827,0.1820474686415423,176.0120781146668,0.082232819131562,76.67864544650627,202.26844,150.45379924382496,211370.0336489226,157223.85859492232,363.33253,265.75997482801927,379174.3264990491,277211.24085942627,354.03014,196.743585306935,367151.53510146926,203221.1426853397,2443.85824,1352.3787597279563,2512608.146801262,1372083.454516469,639.1622,345.9163056500196,655336.8654252095,348923.7614233019,1177.65801,598.6227039805702,1196133.1326937948,594024.3306580855,0.37919,100000,0,919402,9607.728802223755,0,0.0,0,0.0,43699,455.953351307292,0,0.0,44346,459.5794929671662,816083,0,35796,0,0,0,0,0,81,0.8464480531694777,0,0.0,0,0.0,0,0.0,0.04621,0.1218650280861837,0.2945249945899156,0.01361,0.3745847176079734,0.6254152823920266,22.385866952199,4.013309876868882,0.3062265163714439,0.2944176060118089,0.19296833064949,0.2063875469672571,11.825700231202614,6.702859338246835,14.692335826281214,11270.044062760007,43.47127634205143,13.791894438429752,13.26666525583288,8.654076327539933,7.75864032024885,0.6111111111111112,0.8195077484047402,0.7502191060473269,0.5825747724317295,0.1029207232267037,0.7703761755485894,0.920388349514563,0.896,0.6986301369863014,0.1197604790419161,0.5281632653061225,0.7302405498281787,0.6788511749347258,0.5363636363636364,0.0978260869565217,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023505096148001,0.0045119948086711,0.0068208808274378,0.0090752954806451,0.0111709108667121,0.0134852975626648,0.0157883464052954,0.0177269478198713,0.0197556112275678,0.0219466235176044,0.0241098531462794,0.0261714497011031,0.0283024691358024,0.0302939752083998,0.032422221763455,0.0345415998758984,0.0363216199131597,0.0385972925836724,0.040827152917191,0.0426676115934174,0.0578927579220019,0.0709522064597183,0.0842543901082176,0.0965996990139022,0.1080667623227548,0.1238069035575966,0.1381678093095324,0.1522294621183084,0.1658207153008559,0.1784120171673819,0.1929049430477278,0.2004720556072843,0.2071907373552712,0.213704778063598,0.2199632146436556,0.2267466353295935,0.232752652149637,0.2402831229041478,0.2459982290034738,0.2516843118383061,0.2570807108478341,0.2620186404406348,0.2661604154099097,0.2715240513606746,0.2761329011738713,0.279469155104704,0.281978162170275,0.284973500590994,0.2874012183607745,0.2910624835222778,0.2875750154740439,0.2838800142971048,0.2799425643335773,0.2766983283771689,0.2741351688126743,0.2706143031784841,0.2669624670382593,0.2675355295042242,0.2666041915147384,0.2675410535295372,0.2679973883033299,0.2679242313971557,0.2699816452527949,0.2705364487227941,0.2716963113286379,0.2723193563360668,0.2735788022840426,0.2791158442201721,0.2844242236238927,0.2888628827774527,0.2931920790308882,0.2959417273673257,0.2981197427016328,0.2998129442573887,0.3002221810775782,0.3055004087352563,0.3111347087378641,0.3208985158443642,0.3160427807486631,0.3219178082191781,0.0,2.5394923213603446,55.31091524390299,134.38019379501952,173.17729339896448,fqhc3_implementation,41 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-100000,95779,48423,461.3537414255735,4663,47.37990582486766,3692,37.79534135875296,1414,14.314202486975224,77.36144091067452,79.68986891680022,66.21679282253906,68.06218790161718,77.1749768494876,79.50997363433137,66.13341227596868,67.98505902000136,0.1864640611869106,179.89528246884845,0.0833805465703818,77.12888161582043,200.9766,149.5689950319783,209833.67961661745,156160.53104749296,364.15603,266.599088688711,379657.9939235114,277801.6983772132,355.43735,198.3324458184826,367684.20008561376,204213.6816527834,2417.55482,1340.8795075834096,2478401.2361791204,1354276.6238772692,666.64861,359.68271028038583,681020.6203865148,360526.6710660849,1237.08955,622.5006727313837,1253970.421491141,615790.6626121248,0.38054,100000,0,913530,9537.894528028064,0,0.0,0,0.0,43736,455.872372858351,0,0.0,44465,459.6101441860951,821922,0,36041,0,0,0,0,0,84,0.8770189707555937,0,0.0,1,0.0104407020328046,0,0.0,0.04663,0.1225363956482892,0.3032382586317821,0.01414,0.3577018121911038,0.6422981878088962,22.6744384467498,3.8838811581275214,0.3009209100758396,0.2984832069339111,0.2039544962080173,0.1966413867822318,11.252095671760838,6.160290576320759,15.238744492428,11363.05271900937,43.101323165501725,13.864324145739136,12.806195481747368,8.074532021922094,8.356271516093125,0.5983206933911159,0.8348457350272233,0.7047704770477048,0.5550964187327824,0.1367861885790172,0.7665847665847666,0.9272727272727272,0.8746518105849582,0.6931216931216931,0.1797752808988764,0.5151760420882234,0.7594728171334432,0.6236702127659575,0.5065176908752328,0.1234782608695652,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0020864140012559,0.0045008058875406,0.0068080357142857,0.0091201771223708,0.0113264330886389,0.0132945152489922,0.015623726049735,0.0180632519976732,0.0201381367881153,0.0222485909225749,0.0242028035084843,0.0263860095650567,0.0287690663158327,0.031032175032175,0.0333020492775445,0.0351700125016789,0.0371290459481,0.0393259009592947,0.0413272092443262,0.0432288358824325,0.0578899589928733,0.072277186303834,0.0856232242642819,0.097962143585324,0.1109846808689972,0.126461671719359,0.1411573995592473,0.1552055974394691,0.1678424675809808,0.1813477054291806,0.195710426912605,0.2020198743525697,0.2083790686301146,0.2151538999650227,0.2214328134966896,0.22941313177145,0.2364500156131507,0.2431767086330935,0.2495832341033579,0.2555498311294292,0.2609132947976879,0.2655108315699638,0.270140778421862,0.2743040582626611,0.2772804023274741,0.2798660032513917,0.2831361464769004,0.2875545212935058,0.2900720876959116,0.291642522256756,0.2884341493564077,0.2835753238368659,0.2806474749321445,0.2776037531577048,0.2749295356771992,0.2700954303541934,0.2663829383286397,0.266229185464687,0.266650735670638,0.2668354972178627,0.2678400898792248,0.2693225520165664,0.2696128667935499,0.2716966816183526,0.27275128463718,0.2724504931171771,0.2732887579329102,0.2770055475908496,0.2810889848210555,0.2861584477940887,0.2901306894997746,0.2941330265634804,0.2962870979759096,0.2993611424276587,0.3023985239852398,0.30773712421347,0.3161116918022995,0.3188032494551218,0.3292092522861753,0.3367117117117117,0.0,2.989872104033969,52.3082242534846,139.3628043245848,172.1089014288444,fqhc3_implementation,47 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-100000,95729,48025,458.3981865474413,4580,46.68386800238172,3693,37.961328333107,1350,13.694909588525944,77.36081378003848,79.74070208324072,66.19279593561531,68.08100860932673,77.18419088779004,79.56929003902549,66.11402258780618,68.00715629983512,0.1766228922484458,171.4120442152307,0.0787733478091325,73.85230949161325,203.88544,151.60088926497505,212981.89681287805,158364.64317497838,366.46971,267.3156634609138,382349.4552330015,278771.59842985286,349.90966,193.714432272528,362973.8741656133,200149.44853876,2423.10502,1320.1083618891437,2489703.715697437,1337496.277919067,651.08065,345.88033518304377,665539.3558900647,346776.85303207184,1172.99066,587.112448091433,1190346.969048042,582157.4810548342,0.3791,100000,0,926752,9680.995309676273,0,0.0,0,0.0,44058,459.5786020954988,0,0.0,43715,453.1960012117541,810602,0,35411,0,0,0,0,0,91,0.9506001316215568,0,0.0,0,0.0,0,0.0,0.0458,0.1208124505407544,0.2947598253275109,0.0135,0.3655823714585519,0.634417628541448,22.99689503477868,3.9751726652820527,0.3027349038721906,0.2997562956945572,0.1941510966693745,0.2033577037638776,11.547444649779228,6.496755719051427,14.428691906264298,11289.217126310874,42.27627609994,13.59922380973724,12.579398826143436,8.331882596694118,7.7657708673652035,0.6035743298131601,0.8148148148148148,0.7164579606440071,0.5872170439414115,0.1185495118549511,0.7565071368597817,0.931958762886598,0.8682634730538922,0.6989795918367347,0.125,0.530775379696243,0.7234726688102894,0.6517857142857143,0.5477477477477477,0.1164510166358595,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0020265272415924,0.004584829488974,0.0066618598369062,0.0089361053220149,0.0111847260810714,0.013307519869574,0.0154274694664666,0.0176820299092914,0.0196996972424515,0.0216658642272508,0.0238041516245487,0.026021120973044,0.028026421384036,0.0301106737289008,0.0322693827848467,0.0342695874210455,0.0365272685846848,0.0385417639550449,0.0406359505464225,0.0423960156705843,0.0566605067810943,0.0704091242021554,0.0843961068926458,0.0970099039047879,0.1089590164798667,0.1242160481423117,0.138781616024444,0.1533791987049777,0.166194654326661,0.1783725795204634,0.1928850858380661,0.1995539242753976,0.2070470675316758,0.2143537318170375,0.2197977706304798,0.2273881184387021,0.2349999441858388,0.2425422260231582,0.2484376240543514,0.2542085808127625,0.2596908634781905,0.263794291856023,0.2682857682857683,0.2734443260840943,0.2768318416648475,0.2798528126807537,0.2833422870778725,0.2866666666666667,0.2885263688146627,0.2896205797940967,0.2870866755344162,0.2821280041725572,0.2795224719101123,0.2775312626058894,0.2747249492840537,0.2700364646110187,0.2655496358878976,0.2657818698271218,0.2665353796007062,0.2671243812869232,0.2680113128907413,0.2693316628166477,0.2702966391962302,0.2705358921575138,0.2714626012386851,0.2709467654117101,0.270875017613076,0.2766868310842252,0.2812955128649698,0.2853340639555364,0.2894689468946895,0.2943691345151199,0.2975032525865808,0.3013964603091629,0.3042876901798063,0.3117003954408002,0.3085186866394311,0.3146430012101653,0.3195020746887966,0.3211845102505695,0.0,2.270138546859374,51.71766962695501,123.8250548474087,188.2955651048925,fqhc3_implementation,69 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-100000,95688,44967,425.34069057771086,5950,60.87492684558147,4704,48.48047822088454,1899,19.41727280327732,77.3033471490307,79.68353323489619,66.16125749529859,68.04705549391207,77.0568622755306,79.44014843959431,66.05335196269412,67.94355205385398,0.2464848735000941,243.3847953018784,0.1079055326044624,103.5034400580912,138.28672,102.86962031720712,144518.35130841902,107505.24654837296,269.90194,192.59564862815463,281576.83304071566,200786.87884390383,280.81748,155.33802356108532,290358.80152161187,159673.3314475669,3159.83527,1685.457984585615,3257527.401555054,1716769.8719130573,871.8268,445.84010659903305,896125.9719087032,451043.12006850034,1669.19319,828.4534084240523,1707583.939469944,833151.6588678395,0.38039,100000,0,628576,6569.015968564501,0,0.0,0,0.0,32061,334.36794582392776,0,0.0,35341,365.12415349887135,1220631,0,53674,0,0,0,0,0,81,0.8465011286681715,0,0.0,0,0.0,0,0.0,0.0595,0.1564184126817213,0.3191596638655462,0.01899,0.32848,0.67152,24.233098713952028,4.243581478705361,0.3148384353741497,0.2376700680272108,0.2257653061224489,0.2217261904761904,11.214802199428185,5.913439407649906,20.550735740274213,12141.917931781054,53.71235049252654,13.407507965186442,16.78756155208149,11.79607846339578,11.72120251186282,0.5637755102040817,0.7853309481216458,0.6887238352464551,0.5934803451581975,0.1271186440677966,0.7312312312312312,0.9269406392694064,0.8418367346938775,0.7636363636363637,0.1233480176211453,0.4976275207591933,0.6941176470588235,0.6336088154269972,0.5325520833333334,0.1281437125748503,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0025927726462485,0.0051391732722444,0.0072044647387113,0.0095177149358036,0.0116164338972016,0.0138750229212933,0.0159232095314842,0.0184462647845893,0.0204060757939958,0.022698406194944,0.0248876669607501,0.0273085932684009,0.0296317636043748,0.0315230832646331,0.0336271494333546,0.035819537365444,0.0375911803713527,0.0395952257394914,0.041638069091741,0.0434823392081044,0.0587135455836884,0.0730236502402713,0.0857196842458851,0.0988529937914342,0.1102213500453672,0.1258398671026039,0.1404296418943301,0.1543040293040293,0.1678402376347647,0.1803375427829576,0.1949668588672738,0.20394701212049,0.2130421053777724,0.2219143273348594,0.2301707131600119,0.2380502970077166,0.2458853146853147,0.2546656737300566,0.2615717293575371,0.2677933387713836,0.2742289342635263,0.2795142555438226,0.2857125896376501,0.2926644638029438,0.2976258633501029,0.302863994264595,0.3074442994781212,0.31192414690794,0.3151551359143862,0.3179970607316395,0.3179550953649008,0.3154735622033337,0.3139211562619091,0.3129308846532646,0.3124562683300829,0.3106274125359965,0.3088004812639511,0.3100796799685215,0.3095929735825843,0.3098937914320336,0.3106569179273332,0.3118500246669956,0.3118416652733656,0.313425171359039,0.3141835117875834,0.3165317858908636,0.3165400051233882,0.3192890059249506,0.3229881035689293,0.3251258871575274,0.326745298055467,0.3302917771883289,0.3325181840983195,0.3350022758306782,0.3409409783930409,0.338702092640489,0.3387861183305305,0.3433563592035757,0.3475659505031275,0.3479742521772056,0.0,2.6441627774862977,58.09234377484066,174.73716745217413,249.81827274515717,fqhc2_implementation,17 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-100000,95782,45086,427.5020358731286,5831,59.82334885469086,4620,47.70207345847863,1857,18.991042158234325,77.28561848031416,79.63110803065119,66.16917984221747,68.0320698119272,77.04422486814151,79.39286725305068,66.06351800409006,67.93073075654611,0.2413936121726436,238.24077760050957,0.1056618381274177,101.33905538108934,138.70318,103.2702918695224,144811.32154266982,107818.05753640809,272.26302,194.4843138991015,283845.8896243553,202642.00361143163,277.62065,153.1959136574785,287548.3389363346,158056.95296782628,3113.7146,1652.9541599391484,3211010.0645215176,1685921.3839125826,842.2789,434.6457835412128,864213.7353573741,438635.5012048134,1633.45256,809.4526687895258,1670075.6927188826,814048.247115814,0.37995,100000,0,630469,6582.332797394082,0,0.0,0,0.0,32405,337.756572216074,0,0.0,35073,363.0849220103986,1219059,0,53520,0,0,0,0,0,56,0.5846610010231568,0,0.0,0,0.0,0,0.0,0.05831,0.1534675615212528,0.3184702452409535,0.01857,0.3275044941983984,0.6724955058016016,24.470232155378337,4.307146380179545,0.3175324675324675,0.2428571428571428,0.2296536796536796,0.2099567099567099,10.961372371698486,5.741731618059276,20.10045059858202,12066.29542321691,52.90928441577469,13.584610695664194,16.66725388571092,10.936420163233054,11.720999671166508,0.5662337662337662,0.803921568627451,0.6980231765507839,0.5855670103092784,0.1149858623939679,0.7095015576323987,0.9230769230769232,0.8350515463917526,0.7370689655172413,0.1290322580645161,0.5110911270983214,0.7337110481586402,0.6487488415199258,0.537940379403794,0.1107011070110701,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022295414238662,0.0045943204868154,0.0068526527380154,0.0092285801402581,0.0112840862840862,0.0134768967484312,0.015929023047114,0.0179933622670411,0.0202343462435074,0.0222449710805138,0.0242857289306693,0.0263430759596332,0.0283038266197849,0.0306635354222029,0.0327552588955029,0.0347357110385585,0.0365692040089455,0.0385381439448951,0.0405026191070092,0.0422640802174116,0.0570149347193086,0.0717529138504676,0.0857487416107382,0.0988781057125132,0.111396996794331,0.1269621324307171,0.1418825002387344,0.1559489466792987,0.1689077335497858,0.1809894576536576,0.1952527624011889,0.2037123170612986,0.2122866152006089,0.2208172908645432,0.2274558140558625,0.2361937693253981,0.2451591289782244,0.2533270283050733,0.2597081038105514,0.2670427185801747,0.2733179675465317,0.2793693925835695,0.2858684566305353,0.29070535531989,0.2963237798647268,0.3000592343954389,0.3046490359921326,0.3092166426815756,0.3125445520173153,0.3162912298307233,0.3157405536472014,0.3141086552365214,0.3121154823051306,0.3107986664734019,0.3092974036426506,0.3060327606871754,0.3042318380309646,0.3051506316812439,0.3049495781024902,0.3061568233944954,0.3079006262576871,0.3090768375932687,0.3088142442227554,0.3092957366432811,0.3116703807770565,0.3139924591537494,0.3145285935085007,0.3182162947980532,0.3203006457532023,0.3224063400576369,0.3268063982349696,0.3302526844382712,0.3346195205262825,0.339875795445833,0.3437381404174573,0.3473296062804805,0.350462962962963,0.3470720261171189,0.3489525909592061,0.3494113178883403,0.0,2.0720408005424185,56.58360710179304,176.31482200694632,245.58325060661625,fqhc2_implementation,22 -100000,95740,45071,427.14643827031546,5694,58.32462920409443,4497,46.42782536035095,1737,17.819093377898476,77.31924264235211,79.68077355526837,66.18493805092173,68.0578005010164,77.09031411993719,79.4520627423153,66.08437484715436,67.95949379223735,0.2289285224149182,228.71081295306797,0.1005632037673649,98.3067087790488,137.66038,102.50205172902396,143785.64863171088,107062.93266035509,271.48711,194.31733251182587,283152.6634635471,202549.17747213892,278.56808,153.9807510589718,288419.0829329434,158723.30824718613,3005.6501,1604.4271913144612,3109028.023814497,1645456.9890479029,826.93555,429.40719343058015,857017.725088782,441801.1420833306,1531.08981,765.9026951349692,1573118.7278044703,777256.8492206997,0.37987,100000,0,625729,6535.711301441404,0,0.0,0,0.0,32241,336.18132442030503,0,0.0,35128,363.4531021516608,1225247,0,53740,0,0,0,0,0,72,0.7520367662419052,0,0.0,1,0.0104449550866931,0,0.0,0.05694,0.1498933845789349,0.3050579557428872,0.01737,0.3327736736064473,0.6672263263935527,24.341974098153475,4.287486976634324,0.3159884367356015,0.2472759617522793,0.2254836557705136,0.2112519457416055,11.064367680553724,5.665973612185571,18.867092163452245,12094.578403846148,51.46643760416221,13.486209616946557,16.026773245868856,10.7013791110351,11.2520756303117,0.5688236602179231,0.7814748201438849,0.7002111189303307,0.5926315789473684,0.1291913214990138,0.7295401402961809,0.9292237442922374,0.8527777777777777,0.7470355731225297,0.1422413793103448,0.5046670815183572,0.685459940652819,0.648444863336475,0.5365853658536586,0.1253196930946291,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022691816763579,0.0045014903582943,0.0066586816622343,0.0087998292873764,0.0108331892298772,0.0132484725050916,0.0155889969617259,0.017834720024501,0.0199147387468435,0.0220119990990437,0.024102932130408,0.0261909650924024,0.028175966106575,0.0303539057350032,0.0324197757537623,0.0343327685250237,0.0364136960211981,0.0386912786477237,0.0407412411528108,0.0427373574293005,0.057296179906664,0.0713321402781702,0.0846323298017413,0.0971544544460334,0.1089072369322915,0.1241830065359477,0.1393503490123692,0.1540402158755841,0.1674999465846206,0.180165785551135,0.1956205637474015,0.2043393572124228,0.2122606614447345,0.2218039353017137,0.2297343417996058,0.2397666655576626,0.2485695127402771,0.2564587484380804,0.262426892283232,0.269452499111758,0.2757355494340147,0.2807042171141136,0.2867367823299064,0.2920684739509086,0.2973275024295432,0.3021050424831362,0.3067134268537074,0.3109988805210665,0.3142849744957406,0.3186019222909277,0.3171076169852179,0.3155291110714138,0.3140612239150638,0.3129911023804021,0.3110830485811915,0.3072720594986686,0.30496801975809,0.3051409618573797,0.305659023340054,0.3054646274930686,0.3060182142521829,0.3072942482701191,0.3082520188425303,0.3096552652841368,0.310970169050088,0.3114998431126451,0.312269886120387,0.3156868296058633,0.319210821418559,0.3229109020475927,0.3257142857142857,0.3298498753381783,0.3353512422751923,0.3370418349462775,0.3425189393939394,0.3461492394298718,0.3513639181649101,0.3602761982128351,0.3625377643504531,0.3653483992467043,0.0,2.1083942902925643,56.385671997054686,167.78350937943,237.6864886208501,fqhc2_implementation,23 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-100000,95827,44920,424.8906884281048,5819,59.64915942270967,4583,47.3770440481284,1846,19.00299498053785,77.42639796763848,79.74305759021554,66.25868451100193,68.09480162710808,77.19669124135746,79.51332880912287,66.15933705814082,67.99782652980794,0.229706726281023,229.7287810926747,0.0993474528611102,96.97509730014532,138.11006,102.72269224751132,144124.36995836248,107195.98051437624,267.80851,191.48434333514444,279126.7179396203,199478.84556037904,278.16611,153.80777753880523,288061.8823504858,158677.4044947114,3075.16385,1639.7230834867592,3178764.586181348,1680814.3565871406,847.89881,438.8884188439576,875534.4422761853,448712.78329067817,1623.63227,791.4051173911911,1671702.954282196,804477.4024417484,0.37954,100000,0,627773,6551.107725380112,0,0.0,0,0.0,31994,333.402903148382,0,0.0,35028,362.5700481075271,1231895,0,54060,0,0,0,0,0,61,0.6365638076951172,0,0.0,0,0.0,0,0.0,0.05819,0.1533171734204563,0.3172366385976972,0.01846,0.3387942332896461,0.6612057667103539,24.11660618266317,4.327737083097771,0.3216233907920576,0.2354353043857735,0.2221252454723979,0.2208160593497709,11.197123263025956,5.788102198032572,19.691431037059417,12084.70022830667,52.34188510234664,13.118045193093623,16.69400260833294,11.24841300418838,11.281424296731691,0.5666593934104298,0.7775718257645968,0.7089552238805971,0.5889328063241107,0.1149312377210216,0.7420849420849421,0.9277389277389276,0.8516624040920716,0.7933884297520661,0.1630901287553648,0.4975669099756691,0.6784615384615384,0.6574330563250231,0.5246753246753246,0.1006369426751592,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.00208658306829,0.0043286971331251,0.0067069149206027,0.008908346623056,0.0113251664718141,0.0133015805167974,0.0156799217532169,0.0176256387764053,0.0196084438861484,0.0218127153916164,0.0238521962659893,0.0259495163953762,0.028045448008054,0.0302416035561409,0.0321659727089087,0.0346116514879292,0.0369155978485726,0.0389434087399869,0.0410613219793343,0.0428764699760641,0.0579908199457542,0.0718244175833368,0.0856570781616907,0.0986007227498109,0.1101632438125329,0.1252786258332364,0.1394190519589245,0.1532516954737759,0.1661973333333333,0.1787205343952726,0.1934429753842846,0.2028342136245315,0.2125287655768312,0.2218196105823801,0.2301147280013174,0.2396428453029516,0.2479972406426632,0.256332626904834,0.2630667737883743,0.2689698492462311,0.2757916594566534,0.2814114299707312,0.2878242287576298,0.2931394918230579,0.2973437405457735,0.3016700050382786,0.3059433137720065,0.3103930086629576,0.3139596500071084,0.3182698005135295,0.3160575798712383,0.3141696180984543,0.3121510834868449,0.3112054770777364,0.3107058526515883,0.3075723285827879,0.3066822570196091,0.3071660064818149,0.3068855138595655,0.3069063723745105,0.3080637011808297,0.3081414846816989,0.308357771260997,0.3094737313165667,0.3102519715329871,0.3094493931343439,0.3107554999715763,0.3141398960485941,0.3175257731958762,0.3217201743955608,0.3237059947239152,0.3259486962052151,0.3283619817997977,0.327860088590194,0.3328649053775529,0.3362130177514792,0.3378316906747536,0.3451696092045229,0.3351380617217109,0.3414634146341463,0.0,1.7432079369855586,57.18129285680999,170.47676691974155,244.60584258353097,fqhc2_implementation,45 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-100000,95701,45131,427.85341845957726,5903,60.53228283925978,4641,47.88873679480884,1820,18.64139350685991,77.35473615323171,79.74482341393087,66.18997507424481,68.08584441224893,77.11759990330864,79.51027977655473,66.08722950124542,67.98700548994927,0.2371362499230684,234.5436373761487,0.102745572999396,98.83892229966308,138.10588,102.7560644528326,144309.5265462221,107371.75625420074,271.16684,193.59951628529308,282896.82448459265,201845.08655635055,275.33508,152.23189157877084,284830.8063656597,156686.87472810564,3085.88771,1639.3898550672584,3186414.185849678,1674937.968325576,846.1796,433.8346245271244,874752.9074931297,443893.2160866913,1609.19443,789.4894785799079,1650131.451082016,797468.7744872887,0.38313,100000,0,627754,6559.523933919187,0,0.0,0,0.0,32244,336.2974263591812,0,0.0,34770,359.4633284918653,1226623,0,53799,0,0,0,0,0,76,0.7941400821308033,0,0.0,1,0.0104492116069842,0,0.0,0.05903,0.1540730300420223,0.3083178045061833,0.0182,0.3356031128404669,0.664396887159533,24.25358887240789,4.317727772440649,0.3132945485886662,0.2443438914027149,0.2238741650506356,0.2184873949579832,11.053480217804587,5.6905846623864464,19.48170206428068,12166.037967579272,52.66767253883988,13.693560760241578,16.296803957534635,11.306665564614216,11.37064225644944,0.5625942684766214,0.7954144620811288,0.6891334250343879,0.5857988165680473,0.1087584215591915,0.7179289026275116,0.9026128266033254,0.8308080808080808,0.7159533073929961,0.1636363636363636,0.502539587690469,0.7321178120617111,0.6361058601134215,0.5416116248348745,0.094017094017094,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0021582296437401,0.0048064247906061,0.0072167355183158,0.009236303040156,0.0112407556229209,0.013526451954613,0.0158484100597629,0.0179572825054392,0.0200896053681389,0.0223401313161318,0.0243344447294178,0.0263230897265974,0.0285931824963216,0.0303698816543647,0.03248322147651,0.0344766948714235,0.0366731950964238,0.0385996968501484,0.040719322696732,0.0428352562298721,0.0576832694496955,0.0711675966541388,0.0846390378540619,0.0972418000883633,0.1094344795588033,0.1244369250290789,0.1398154042011457,0.1528781765338386,0.16620732384737,0.1797917850518393,0.1949481028468065,0.204114968142531,0.2131571793617137,0.2212575177692728,0.2292033450704225,0.2380641159137736,0.2463816633747335,0.2546630667116661,0.2625452400131607,0.2700997400574851,0.2764888394924516,0.2830513234571368,0.2890988526977587,0.2945487256371814,0.2994166970470288,0.3037856095065517,0.3085460877408363,0.313195143392236,0.3175656411186853,0.3212594478373851,0.3200107548564899,0.3186490051665384,0.3174784052221378,0.3157552741397484,0.3140872456325234,0.3115097892142606,0.3095667584417228,0.3104770017035775,0.3103424750989221,0.3107404103479037,0.3121443545971847,0.3132392367134521,0.3145310904050195,0.316646642637832,0.318427213224404,0.3193046897229623,0.32026495315198,0.3231739687099897,0.3276670164393144,0.3301543332014246,0.3340294171055021,0.3359159414137125,0.3370207416719045,0.3377710155952834,0.3368648040502531,0.3377037562012757,0.3435415403274712,0.3477473853580048,0.3549088931193908,0.3570892723180795,0.0,2.267944309133786,56.59650396512665,168.86226015607616,251.63864433990892,fqhc2_implementation,47 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-100000,95662,44915,426.3030252346804,5908,60.56741443833496,4651,48.01279504923585,1823,18.64899333068512,77.2965961837345,79.70765863643216,66.15033914380253,68.06240282626483,77.06613196813963,79.48085858169628,66.05104521443288,67.96804962012328,0.2304642155948641,226.80005473587528,0.0992939293696508,94.35320614154818,137.49428,102.29862313092202,143729.25508561396,106937.57514051769,269.88652,192.65326669544427,281671.32194601826,200935.7599626228,276.2956,152.45793286344406,286470.69891911105,157344.9363468888,3121.25415,1649.4592776103923,3223254.688382012,1685517.6618376833,838.4642,427.4314314368746,864064.3097572704,434712.4751918146,1599.05297,774.1314055209971,1636746.0224540571,776449.4920185299,0.38096,100000,0,624974,6533.147958436996,0,0.0,0,0.0,32108,335.0128577700654,0,0.0,34919,361.8469193619201,1228320,0,53815,0,0,0,0,0,71,0.7421964834521544,0,0.0,0,0.0,0,0.0,0.05908,0.1550818983620327,0.3085646580907244,0.01823,0.3401811711420252,0.6598188288579747,24.20977772712133,4.308994239132786,0.3169210922382283,0.2403784132444635,0.212642442485487,0.2300580520318211,11.336600657522531,5.968604761751148,19.37185212664857,12143.475070450831,53.03846385981989,13.577969551567534,16.75121965133445,11.9022966163998,10.806978040518114,0.5766501827563965,0.8023255813953488,0.7116689280868386,0.5822429906542056,0.1142568250758341,0.739329268292683,0.9155251141552512,0.854320987654321,0.7692307692307693,0.1486486486486486,0.5127283617849656,0.7294117647058823,0.6576239476145931,0.5261239368165249,0.1043024771838331,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0025134286003851,0.0046458785579517,0.0067311694772429,0.0092482494384991,0.0114163614163614,0.0135400853769115,0.0156391867214837,0.0176820299092914,0.0196473500112504,0.0214703502248445,0.0236876391353857,0.0256866028953938,0.0278652425346257,0.0299859811157382,0.0321081973983068,0.0341774246938099,0.0362511143822694,0.0381807039956792,0.0402014756845073,0.0422425032594524,0.0571141970471145,0.0709467951403435,0.0846525299181188,0.0972580390505762,0.1093365704333139,0.1248173946181695,0.1389160259949879,0.1521801659759878,0.1656297436555277,0.1787293885262796,0.1938109871152083,0.2038665655799848,0.2129730435918651,0.2214205951260099,0.2288560503377522,0.2381110852274618,0.2470139998435771,0.2558142154047144,0.263596805162639,0.2708041917952716,0.2771417657340633,0.2839072793437942,0.2896410426461706,0.2948756403949752,0.2995817018896374,0.3052280723412135,0.3091781989570798,0.313407159150281,0.317314304249108,0.3211590064903306,0.3195972177288903,0.3176736556249397,0.3153361759805721,0.3138359497190523,0.3123948485074071,0.3096162999585438,0.3086253155312832,0.3092664791327378,0.3096325957869158,0.3109275253473526,0.3122938530734632,0.312395061728395,0.3132767473540815,0.3136163458744104,0.3135863441298458,0.3150581757739455,0.3161433069525998,0.3198600612232148,0.3234199450415667,0.3275328238291201,0.3299977462249267,0.3345319936541512,0.3360326428123038,0.3380207152037499,0.3423230726308937,0.3465160075329567,0.345756623259991,0.3556261162929152,0.3613148600923662,0.3586579251831855,0.0,2.3677139144114445,57.52982563450204,169.85017424510545,250.90497524051332,fqhc2_implementation,93 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-100000,95687,47526,452.71562490202433,4941,50.38301963694128,4009,41.32222767983112,1589,16.261352116797475,77.31064774199393,79.69127351335871,66.17768057244363,68.06312103733008,77.10233803387021,79.48437065362565,66.0854627708245,67.97378150813611,0.2083097081237213,206.90285973306288,0.0922178016191281,89.33952919396404,187.59004,139.60887369494975,196045.48162237293,145901.61014030094,345.00677,251.2862153370433,360113.7772111154,262168.85819081304,338.39968,187.98103110960017,350874.23578960565,194157.00663380013,2634.32835,1443.8119755364846,2719400.190203476,1475222.428894714,715.57803,382.89592657531983,737254.8517562469,389577.4207314685,1381.8672,694.671419754999,1415714.6947861256,701073.7365022325,0.38092,100000,0,852682,8911.158255562406,0,0.0,0,0.0,41302,431.0094370186128,0,0.0,42470,440.059778235288,905699,0,39735,0,0,0,0,0,85,0.8883129369715844,0,0.0,0,0.0,0,0.0,0.04941,0.1297122755434211,0.3215948188625784,0.01589,0.3502429543245869,0.649757045675413,23.00405614925861,4.056498022462699,0.3093040658518334,0.2763781491643801,0.2030431529059616,0.2112746320778249,11.253386892948113,6.140526887407869,17.248569151388068,11504.49741120917,46.53140379306125,13.715782264431008,14.07540770464287,9.652886878650325,9.087326945337049,0.5784484908954851,0.7833935018050542,0.682258064516129,0.5938606847697757,0.1253071253071253,0.725614591593973,0.8818737270875764,0.8314606741573034,0.7242990654205608,0.155,0.5109170305676856,0.7050243111831442,0.6221719457013575,0.5497630331753555,0.1156351791530944,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024104683195592,0.0045517213413892,0.0067186294807778,0.0088482989119944,0.010943745486722,0.0130953229534739,0.0153574742767404,0.0175811161252118,0.0198163561627027,0.0221892279336473,0.0245403177012295,0.0266852922748235,0.0286981396114586,0.0308515353612402,0.0326767019760887,0.0346389747939141,0.0365162426817263,0.038766611295681,0.0410485800478518,0.0432417221649001,0.0579516373322191,0.0724056727196608,0.0859520087295008,0.0982182300103077,0.1096569397719962,0.1254044451963542,0.1406790450928381,0.154651138033087,0.1675963326280695,0.1802348042582417,0.1955856360736302,0.2029035715445658,0.2105446433429457,0.2173546756529064,0.2241827187671986,0.2306328272193283,0.2382223214784211,0.2460177190395245,0.2516647348923888,0.2571805157593123,0.2629294881438705,0.267133309142837,0.2718863991662324,0.2765462309869967,0.2800821554877678,0.2835020405143822,0.2879080137277988,0.2918741958906029,0.2938764387578993,0.2965352228112152,0.294496155402671,0.2908218819345857,0.2873289120925638,0.2850009407882358,0.2818406038274099,0.2779864187500958,0.2752694298058206,0.2754326962513329,0.2751034223392252,0.2755731450779049,0.2772112343992665,0.2779735075875371,0.2790484140233722,0.2797839951998933,0.280723986228003,0.2821000521104742,0.2823475705440954,0.2880526810912511,0.2928143922158832,0.2951364175563464,0.2991979700031719,0.3020180199167501,0.305591920703198,0.3092329868750474,0.3157795572303344,0.3206216377764495,0.3239501615136133,0.3264386647552734,0.3329599551946233,0.3496369889186091,0.0,2.146207929802805,55.172051648998426,150.1168529736523,197.25579347308917,fqhc5_implementation,41 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crcsim/experiment/prepare.py | 30 +- crcsim/experiment/run_iteration.sh | 6 +- .../experiment/scenarios/all_FIT/params.json | 1214 ------------- .../scenarios/all_FIT_IRR/params.json | 1214 ------------- .../scenarios/all_FIT_start_45/params.json | 1214 ------------- .../all_FIT_start_45_IRR/params.json | 1214 ------------- .../scenarios/all_colonoscopy/params.json | 1214 ------------- .../scenarios/all_colonoscopy_IRR/params.json | 1214 ------------- .../all_colonoscopy_start_45/params.json | 1214 ------------- .../all_colonoscopy_start_45_IRR/params.json | 1214 ------------- .../scenarios/fqhc1_baseline/params.json | 2 +- .../params.json | 1214 ------------- .../params.json | 2 +- .../params.json | 2 +- .../fqhc1_implementation/params.json | 74 +- .../params.json | 77 +- .../params.json | 74 +- .../params.json | 74 +- .../scenarios/fqhc2_baseline/params.json | 2 +- .../params.json | 1214 ------------- .../params.json | 2 +- .../params.json | 2 +- .../fqhc2_implementation/params.json | 74 +- .../params.json | 77 +- .../params.json | 74 +- .../params.json | 74 +- .../scenarios/fqhc3_baseline/params.json | 2 +- .../params.json | 1214 ------------- .../params.json | 2 +- .../params.json | 2 +- .../fqhc3_implementation/params.json | 74 +- .../params.json | 77 +- .../params.json | 74 +- .../params.json | 74 +- .../scenarios/fqhc4_baseline/params.json | 2 +- .../params.json | 1214 ------------- .../params.json | 2 +- .../params.json | 2 +- .../fqhc4_implementation/params.json | 74 +- .../params.json | 77 +- .../params.json | 74 +- .../params.json | 74 +- .../scenarios/fqhc5_baseline/params.json | 2 +- .../params.json | 1214 ------------- .../params.json | 2 +- .../params.json | 2 +- .../fqhc5_implementation/params.json | 74 +- .../params.json | 77 +- .../params.json | 74 +- .../params.json | 74 +- .../scenarios/fqhc6_baseline/params.json | 2 +- .../params.json | 1214 ------------- .../params.json | 2 +- .../params.json | 2 +- .../fqhc6_implementation/params.json | 74 +- .../params.json | 77 +- .../params.json | 74 +- .../params.json | 74 +- .../scenarios/fqhc7_baseline/params.json | 2 +- .../params.json | 1214 ------------- .../params.json | 2 +- .../params.json | 2 +- .../fqhc7_implementation/params.json | 74 +- .../params.json | 77 +- .../params.json | 74 +- .../params.json | 74 +- .../scenarios/fqhc8_baseline/params.json | 2 +- .../params.json | 1214 ------------- .../params.json | 2 +- .../params.json | 2 +- .../fqhc8_implementation/params.json | 74 +- .../params.json | 77 +- .../params.json | 74 +- .../params.json | 74 +- .../scenarios/no_screening/params.json | 1214 ------------- .../scenarios/no_screening_IRR/params.json | 1214 ------------- crcsim/experiment/summarize.py | 4 +- crcsim/experiment/summary/combined.csv | 1601 ----------------- crcsim/experiment/summary/summarized.xlsx | Bin 89499 -> 0 bytes 79 files changed, 1236 insertions(+), 24697 deletions(-) delete mode 100644 crcsim/experiment/scenarios/all_FIT/params.json delete mode 100644 crcsim/experiment/scenarios/all_FIT_IRR/params.json delete mode 100644 crcsim/experiment/scenarios/all_FIT_start_45/params.json delete mode 100644 crcsim/experiment/scenarios/all_FIT_start_45_IRR/params.json delete mode 100644 crcsim/experiment/scenarios/all_colonoscopy/params.json delete mode 100644 crcsim/experiment/scenarios/all_colonoscopy_IRR/params.json delete mode 100644 crcsim/experiment/scenarios/all_colonoscopy_start_45/params.json delete mode 100644 crcsim/experiment/scenarios/all_colonoscopy_start_45_IRR/params.json delete mode 100644 crcsim/experiment/scenarios/fqhc1_baseline_Lower_repeat_compliance/params.json rename crcsim/experiment/scenarios/{fqhc1_baseline_Lower_compliance_with_diagnostic_colonoscopy => fqhc1_baseline_lower_diagnostic_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc1_implementation_Lower_compliance_with_diagnostic_colonoscopy => fqhc1_implementation_lower_diagnostic_compliance}/params.json (96%) delete mode 100644 crcsim/experiment/scenarios/fqhc2_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json rename crcsim/experiment/scenarios/{fqhc2_baseline_Lower_repeat_compliance => fqhc2_baseline_lower_diagnostic_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc2_implementation_Lower_compliance_with_diagnostic_colonoscopy => fqhc2_implementation_lower_diagnostic_compliance}/params.json (96%) delete mode 100644 crcsim/experiment/scenarios/fqhc3_baseline_Lower_repeat_compliance/params.json rename crcsim/experiment/scenarios/{fqhc3_baseline_Lower_compliance_with_diagnostic_colonoscopy => fqhc3_baseline_lower_diagnostic_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc3_implementation_Lower_compliance_with_diagnostic_colonoscopy => fqhc3_implementation_lower_diagnostic_compliance}/params.json (96%) delete mode 100644 crcsim/experiment/scenarios/fqhc4_baseline_Lower_repeat_compliance/params.json rename crcsim/experiment/scenarios/{fqhc4_baseline_Lower_compliance_with_diagnostic_colonoscopy => fqhc4_baseline_lower_diagnostic_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc4_implementation_Lower_compliance_with_diagnostic_colonoscopy => fqhc4_implementation_lower_diagnostic_compliance}/params.json (96%) delete mode 100644 crcsim/experiment/scenarios/fqhc5_baseline_Lower_repeat_compliance/params.json rename crcsim/experiment/scenarios/{fqhc5_baseline_Lower_compliance_with_diagnostic_colonoscopy => fqhc5_baseline_lower_diagnostic_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc5_implementation_Lower_compliance_with_diagnostic_colonoscopy => fqhc5_implementation_lower_diagnostic_compliance}/params.json (96%) delete mode 100644 crcsim/experiment/scenarios/fqhc6_baseline_Lower_repeat_compliance/params.json rename crcsim/experiment/scenarios/{fqhc6_baseline_Lower_compliance_with_diagnostic_colonoscopy => fqhc6_baseline_lower_diagnostic_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc6_implementation_Lower_compliance_with_diagnostic_colonoscopy => fqhc6_implementation_lower_diagnostic_compliance}/params.json (96%) delete mode 100644 crcsim/experiment/scenarios/fqhc7_baseline_Lower_repeat_compliance/params.json rename crcsim/experiment/scenarios/{fqhc7_baseline_Lower_compliance_with_diagnostic_colonoscopy => fqhc7_baseline_lower_diagnostic_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc7_implementation_Lower_compliance_with_diagnostic_colonoscopy => fqhc7_implementation_lower_diagnostic_compliance}/params.json (96%) delete mode 100644 crcsim/experiment/scenarios/fqhc8_baseline_Lower_repeat_compliance/params.json rename crcsim/experiment/scenarios/{fqhc8_baseline_Lower_compliance_with_diagnostic_colonoscopy => fqhc8_baseline_lower_diagnostic_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc8_implementation_Lower_compliance_with_diagnostic_colonoscopy => fqhc8_implementation_lower_diagnostic_compliance}/params.json (96%) delete mode 100644 crcsim/experiment/scenarios/no_screening/params.json delete mode 100644 crcsim/experiment/scenarios/no_screening_IRR/params.json delete mode 100644 crcsim/experiment/summary/combined.csv delete mode 100644 crcsim/experiment/summary/summarized.xlsx diff --git a/crcsim/experiment/prepare.py b/crcsim/experiment/prepare.py index 1effe36..648325e 100644 --- a/crcsim/experiment/prepare.py +++ b/crcsim/experiment/prepare.py @@ -95,15 +95,16 @@ def transform(params): # TODO: add transform function to handle lowered repeat compliance -def transform_repeat_Compliance(rate) -> Callable: +def transform_repeat_compliance(rate: float, test: str) -> Callable: def transform(params): - params["lowered_repeat_compliance"] = rate - + params["tests"][test]["compliance_rate_given_prev_compliant"] = [ + rate for _ in params["tests"][test]["compliance_rate_given_prev_compliant"] + ] return transform # TODO: add transform function to handle lowered diagnostic compliance -def transform_Compliance_with_diagnostic_colonoscopy(rate) -> Callable: +def transform_diagnostic_compliance(rate) -> Callable: def transform(params): params["diagnostic_compliance_rate"] = rate @@ -124,8 +125,8 @@ def create_scenarios() -> List: } low_initial_stage_3_treatment_cost = 67_300 low_initial_stage_4_treatment_cost = 97_931 - diagnostic_compliance_rate= 1.0 - lower_repeat_compliance=0.0 + diagnostic_compliance_rate= 0.525 + lower_repeat_compliance=0.8 scenarios = [] for fqhc, rates in initial_compliance.items(): @@ -140,14 +141,13 @@ def create_scenarios() -> List: scenarios.append(implementation) # TODO: Sensitivity Analysis 1. Lower repeat compliance (note that the baseline runs stay the same) - baseline_lower_repeat_compliance = copy(baseline) - baseline_lower_repeat_compliance.name = f"{fqhc}_baseline_Lower_repeat_compliance" - scenarios.append(baseline_lower_repeat_compliance) + + test_name = "FIT" implementation_lower_repeat_compliance = copy(implementation) implementation_lower_repeat_compliance.transform( - transform_repeat_Compliance(lower_repeat_compliance) + transform_repeat_compliance(lower_repeat_compliance, test_name) ) - implementation_lower_repeat_compliance.name = f"{fqhc}_implementation_Lower_repeat_compliance" + implementation_lower_repeat_compliance.name = f"{fqhc}_implementation_lower_repeat_compliance" scenarios.append(implementation_lower_repeat_compliance) # Sensitivity analysis 2. Lower cost for stage III and stage IV initial phase @@ -172,16 +172,16 @@ def create_scenarios() -> List: # TODO: Sensitivity analysis 3. Lower compliance with diagnostic colonoscopy baseline_lower_compliance = copy(baseline) baseline_lower_compliance.transform( - transform_Compliance_with_diagnostic_colonoscopy(diagnostic_compliance_rate) + transform_diagnostic_compliance(diagnostic_compliance_rate) ) - baseline_lower_compliance.name = f"{fqhc}_baseline_Lower_compliance_with_diagnostic_colonoscopy" + baseline_lower_compliance.name = f"{fqhc}_baseline_lower_diagnostic_compliance" scenarios.append(baseline_lower_compliance) implementation_lower_compliance = copy(implementation) implementation_lower_compliance.transform( - transform_Compliance_with_diagnostic_colonoscopy(diagnostic_compliance_rate) + transform_diagnostic_compliance(diagnostic_compliance_rate) ) - implementation_lower_compliance.name = f"{fqhc}_implementation_Lower_compliance_with_diagnostic_colonoscopy" + implementation_lower_compliance.name = f"{fqhc}_implementation_lower_diagnostic_compliance" scenarios.append(implementation_lower_compliance) return scenarios diff --git a/crcsim/experiment/run_iteration.sh b/crcsim/experiment/run_iteration.sh index 89e0710..2141897 100755 --- a/crcsim/experiment/run_iteration.sh +++ b/crcsim/experiment/run_iteration.sh @@ -12,7 +12,7 @@ if [ ! -d "$output_dir" ]; then mkdir $output_dir fi -aws s3 cp "s3://crcsim-exp-crccp-replication/scenarios/$scenario/params.json" "./params.json" +aws s3 cp "s3://crcsim-exp-crccp-sensitivity01/scenarios/$scenario/params.json" "./params.json" crc-simulate \ --npeople=$npeople \ @@ -23,5 +23,5 @@ crc-simulate \ crc-analyze \ --params-file=./params.json && -aws s3 cp ./results.csv "s3://crcsim-exp-crccp-replication/scenarios/$scenario/results_$iteration.csv" -aws s3 cp ./output.csv "s3://crcsim-exp-crccp-replication/scenarios/$scenario/output_$iteration.csv" \ No newline at end of file +aws s3 cp ./results.csv "s3://crcsim-exp-crccp-sensitivity01/scenarios/$scenario/results_$iteration.csv" +aws s3 cp ./output.csv "s3://crcsim-exp-crccp-sensitivity01/scenarios/$scenario/output_$iteration.csv" \ No newline at end of file diff --git a/crcsim/experiment/scenarios/all_FIT/params.json b/crcsim/experiment/scenarios/all_FIT/params.json deleted file mode 100644 index ee83598..0000000 --- a/crcsim/experiment/scenarios/all_FIT/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - "cost_treatment_stage1_terminal": 68339, - "cost_treatment_stage2_initial": 47790, - "cost_treatment_stage2_ongoing": 3266, - "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 71594, - "cost_treatment_stage3_ongoing": 5258, - "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 110161, - "cost_treatment_stage4_ongoing": 26474, - "cost_treatment_stage4_terminal": 99255, - "max_ongoing_treatments": 4, - "value_loss_cancer": 0.15, - "value_life_year_ages": [ - 0, - 65, - 100 - ], - "value_life_year_dollars": [ - 217000, - 547000, - 547000 - ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 1.0, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 0.07, - "sensitivity_polyp2": 0.07, - "sensitivity_polyp3": 0.22, - "sensitivity_cancer": 0.74, - "cost": 22, - "proportion_perforation": 0, - "cost_perforation": 0, - "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 - ], - "compliance_rate_given_not_prev_compliant": [ - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0 - ] - }, - "Colonoscopy": { - "proportion": 0.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 10, - "specificity": 0.86, - "sensitivity_polyp1": 0.75, - "sensitivity_polyp2": 0.85, - "sensitivity_polyp3": 0.95, - "sensitivity_cancer": 0.95, - "cost": 700, - "proportion_perforation": 0.001, - "cost_perforation": 6487, - "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 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a/crcsim/experiment/scenarios/all_colonoscopy_IRR/params.json b/crcsim/experiment/scenarios/all_colonoscopy_IRR/params.json deleted file mode 100644 index 4babeeb..0000000 --- a/crcsim/experiment/scenarios/all_colonoscopy_IRR/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - 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- 0.00298, - 0.00255, - 0.00234, - 0.00211, - 0.00188, - 0.00168, - 0.0014, - 0.0012, - 0.00099, - 0.00079, - 0.00064, - 0.00049, - 0.00036, - 0.00027, - 0.00019, - 0.00028 - ] -} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json index 4eb030b..2ea5e5c 100644 --- a/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.522, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc1_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc1_baseline_lower_diagnostic_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc1_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc1_baseline_lower_diagnostic_compliance/params.json index 4eb030b..2ea5e5c 100644 --- a/crcsim/experiment/scenarios/fqhc1_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc1_baseline_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.522, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc1_implementation/params.json b/crcsim/experiment/scenarios/fqhc1_implementation/params.json index 20c819f..affe96a 100644 --- a/crcsim/experiment/scenarios/fqhc1_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc1_implementation/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.593, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc1_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc1_implementation_Lower_repeat_compliance/params.json index 4395fa9..affe96a 100644 --- a/crcsim/experiment/scenarios/fqhc1_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc1_implementation_Lower_repeat_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.593, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, @@ -1210,6 +1210,5 @@ 0.00027, 0.00019, 0.00028 - ], - "lowered_repeat_compliance": 0.0 + ] } \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json index 20c819f..affe96a 100644 --- a/crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.593, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc1_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc1_implementation_lower_diagnostic_compliance/params.json similarity index 96% rename from crcsim/experiment/scenarios/fqhc1_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc1_implementation_lower_diagnostic_compliance/params.json index 20c819f..affe96a 100644 --- a/crcsim/experiment/scenarios/fqhc1_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc1_implementation_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.593, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc2_baseline/params.json b/crcsim/experiment/scenarios/fqhc2_baseline/params.json index ff67e6a..9ca2f28 100644 --- a/crcsim/experiment/scenarios/fqhc2_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc2_baseline/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.154, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc2_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc2_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json deleted file mode 100644 index ff67e6a..0000000 --- a/crcsim/experiment/scenarios/fqhc2_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - "cost_treatment_stage1_terminal": 68339, - "cost_treatment_stage2_initial": 47790, - "cost_treatment_stage2_ongoing": 3266, - "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, - "cost_treatment_stage3_ongoing": 5258, - "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, - "cost_treatment_stage4_ongoing": 26474, - "cost_treatment_stage4_terminal": 99255, - "max_ongoing_treatments": 4, - "value_loss_cancer": 0.15, - "value_life_year_ages": [ - 0, - 65, - 100 - ], - "value_life_year_dollars": [ - 217000, - 547000, - 547000 - ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 0.154, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 0.07, - "sensitivity_polyp2": 0.07, - "sensitivity_polyp3": 0.22, - "sensitivity_cancer": 0.74, - "cost": 22, - "proportion_perforation": 0, - "cost_perforation": 0, - "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 - ], - "compliance_rate_given_not_prev_compliant": [ - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0 - ] - }, - "Colonoscopy": { - "proportion": 0.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 10, - "specificity": 0.86, - "sensitivity_polyp1": 0.75, - 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3, - 4, - 5, - 6, - 7, - 8, - 9, - 10, - 11, - 12, - 13, - 14, - 15, - 16, - 17, - 18, - 19, - 20, - 21, - 22, - 23, - 24, - 25, - 26, - 27, - 28, - 29, - 30, - 31, - 32, - 33, - 34, - 35, - 36, - 37, - 38, - 39, - 40, - 41, - 42, - 43, - 44, - 45, - 46, - 47, - 48, - 49, - 50, - 51, - 52, - 53, - 54, - 55, - 56, - 57, - 58, - 59, - 60, - 61, - 62, - 63, - 64, - 65, - 66, - 67, - 68, - 69, - 70, - 71, - 72, - 73, - 74, - 75, - 76, - 77, - 78, - 79, - 80, - 81, - 82, - 83, - 84, - 85, - 86, - 87, - 88, - 89, - 90, - 91, - 92, - 93, - 94, - 95, - 96, - 97, - 98, - 99, - 100 - ], - "death_rate_black_male_rates": [ - 0.011882, - 0.000622, - 0.000406, - 0.000347, - 0.000231, - 0.000231, - 0.000211, - 0.000192, - 0.000169, - 0.000142, - 0.000125, - 0.00014, - 0.000211, - 0.000352, - 0.000546, - 0.000757, - 0.000965, - 0.001172, - 0.00137, - 0.001554, - 0.001736, - 0.001909, - 0.002051, - 0.002154, - 0.002225, - 0.002287, - 0.002346, - 0.002397, - 0.002444, - 0.002494, - 0.002543, - 0.002598, 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0.001709, - 0.00184, - 0.001979, - 0.002133, - 0.002311, - 0.00252, - 0.002762, - 0.003018, - 0.003292, - 0.0036, - 0.003941, - 0.004301, - 0.004674, - 0.00505, - 0.005425, - 0.005806, - 0.006206, - 0.006644, - 0.007124, - 0.007647, - 0.008217, - 0.008842, - 0.009515, - 0.010293, - 0.011188, - 0.01228, - 0.013537, - 0.014827, - 0.01657, - 0.018235, - 0.020046, - 0.021938, - 0.024382, - 0.027026, - 0.029965, - 0.033566, - 0.037224, - 0.041748, - 0.046426, - 0.052066, - 0.059213, - 0.066359, - 0.073798, - 0.081793, - 0.092586, - 0.104549, - 0.117741, - 0.132206, - 0.147969, - 0.165031, - 0.183365, - 0.202911, - 0.223578, - 0.245236, - 0.267725, - 0.290853, - 0.314404, - 1.0 - ], - "death_rate_white_male_ages": [ - 0, - 1, - 2, - 3, - 4, - 5, - 6, - 7, - 8, - 9, - 10, - 11, - 12, - 13, - 14, - 15, - 16, - 17, - 18, - 19, - 20, - 21, - 22, - 23, - 24, - 25, - 26, - 27, - 28, - 29, - 30, - 31, - 32, - 33, - 34, - 35, - 36, - 37, - 38, - 39, - 40, - 41, - 42, - 43, - 44, - 45, - 46, - 47, - 48, - 49, - 50, - 51, - 52, - 53, - 54, - 55, - 56, - 57, - 58, - 59, - 60, - 61, - 62, - 63, - 64, - 65, - 66, - 67, - 68, - 69, - 70, - 71, - 72, - 73, - 74, - 75, - 76, - 77, - 78, - 79, - 80, - 81, - 82, - 83, - 84, - 85, - 86, - 87, - 88, - 89, - 90, - 91, - 92, - 93, - 94, - 95, - 96, - 97, - 98, - 99, - 100 - ], - "death_rate_white_male_rates": [ - 0.005273, - 0.000389, - 0.000273, - 0.000199, - 0.000147, - 0.000143, - 0.000126, - 0.000112, - 0.0001, - 9.1e-05, - 9e-05, - 0.000105, - 0.000145, - 0.000215, - 0.000309, - 0.000412, - 0.00052, - 0.000642, - 0.000778, - 0.000921, - 0.001068, - 0.001209, - 0.00133, - 0.001424, - 0.001497, - 0.001561, - 0.001624, - 0.001682, - 0.001737, - 0.001792, - 0.001847, - 0.0019, - 0.001952, - 0.002003, - 0.002053, - 0.002111, - 0.002174, - 0.002233, - 0.002285, - 0.00234, - 0.002413, - 0.002516, - 0.002649, - 0.002811, - 0.002999, - 0.003203, - 0.003433, - 0.003709, - 0.004047, - 0.004445, - 0.004874, - 0.005331, - 0.005844, - 0.006408, - 0.007003, - 0.007607, - 0.008219, - 0.008857, - 0.009542, - 0.010285, - 0.011098, - 0.011952, - 0.012814, - 0.013657, - 0.014502, - 0.015384, - 0.016444, - 0.017624, - 0.018968, - 0.020586, - 0.022109, - 0.024359, - 0.026347, - 0.02881, - 0.031309, - 0.034486, - 0.038026, - 0.042286, - 0.046547, - 0.051534, - 0.057008, - 0.062923, - 0.069911, - 0.078099, - 0.086754, - 0.096549, - 0.106472, - 0.119677, - 0.134128, - 0.149846, - 0.166829, - 0.185047, - 0.204441, - 0.224919, - 0.246354, - 0.26859, - 0.291442, - 0.3147, - 0.338142, - 0.361537, - 1.0 - ], - "us_age_distribution_rates": [ - 0.01237, - 0.01236, - 0.01234, - 0.01231, - 0.01208, - 0.01214, - 0.01213, - 0.01209, - 0.01211, - 0.01225, - 0.01225, - 0.01225, - 0.01264, - 0.0127, - 0.0126, - 0.01257, - 0.01262, - 0.01257, - 0.01257, - 0.01293, - 0.01318, - 0.01304, - 0.0131, - 0.01319, - 0.01332, - 0.01362, - 0.01389, - 0.01409, - 0.01443, - 0.01466, - 0.0146, - 0.01401, - 0.01366, - 0.0134, - 0.01342, - 0.01348, - 0.01304, - 0.0132, - 0.01317, - 0.01301, - 0.01323, - 0.01241, - 0.01214, - 0.012, - 0.01164, - 0.01197, - 0.01159, - 0.01174, - 0.01224, - 0.0129, - 0.01303, - 0.01232, - 0.01204, - 0.01203, - 0.01223, - 0.01294, - 0.01315, - 0.01311, - 0.01306, - 0.01319, - 0.01326, - 0.01278, - 0.01266, - 0.01248, - 0.01198, - 0.01183, - 0.01129, - 0.01081, - 0.01033, - 0.00995, - 0.00965, - 0.0093, - 0.00912, - 0.00941, - 0.00689, - 0.00671, - 0.00645, - 0.00649, - 0.00557, - 0.00499, - 0.00462, - 0.00424, - 0.00395, - 0.00352, - 0.00324, - 0.00298, - 0.00255, - 0.00234, - 0.00211, - 0.00188, - 0.00168, - 0.0014, - 0.0012, - 0.00099, - 0.00079, - 0.00064, - 0.00049, - 0.00036, - 0.00027, - 0.00019, - 0.00028 - ] -} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json index ff67e6a..9ca2f28 100644 --- a/crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.154, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc2_baseline_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc2_baseline_lower_diagnostic_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc2_baseline_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc2_baseline_lower_diagnostic_compliance/params.json index ff67e6a..9ca2f28 100644 --- a/crcsim/experiment/scenarios/fqhc2_baseline_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc2_baseline_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.154, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc2_implementation/params.json b/crcsim/experiment/scenarios/fqhc2_implementation/params.json index de6a9e4..13dee62 100644 --- a/crcsim/experiment/scenarios/fqhc2_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc2_implementation/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.421, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json index 2244d73..13dee62 100644 --- a/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.421, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, @@ -1210,6 +1210,5 @@ 0.00027, 0.00019, 0.00028 - ], - "lowered_repeat_compliance": 0.0 + ] } \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json index de6a9e4..13dee62 100644 --- a/crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.421, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc2_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc2_implementation_lower_diagnostic_compliance/params.json similarity index 96% rename from crcsim/experiment/scenarios/fqhc2_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc2_implementation_lower_diagnostic_compliance/params.json index de6a9e4..13dee62 100644 --- a/crcsim/experiment/scenarios/fqhc2_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc2_implementation_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.421, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc3_baseline/params.json b/crcsim/experiment/scenarios/fqhc3_baseline/params.json index 05d0e77..3cfb63e 100644 --- a/crcsim/experiment/scenarios/fqhc3_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc3_baseline/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.519, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc3_baseline_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc3_baseline_Lower_repeat_compliance/params.json deleted file mode 100644 index 05d0e77..0000000 --- a/crcsim/experiment/scenarios/fqhc3_baseline_Lower_repeat_compliance/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - "cost_treatment_stage1_terminal": 68339, - "cost_treatment_stage2_initial": 47790, - "cost_treatment_stage2_ongoing": 3266, - "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, - "cost_treatment_stage3_ongoing": 5258, - "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, - "cost_treatment_stage4_ongoing": 26474, - "cost_treatment_stage4_terminal": 99255, - "max_ongoing_treatments": 4, - "value_loss_cancer": 0.15, - "value_life_year_ages": [ - 0, - 65, - 100 - ], - "value_life_year_dollars": [ - 217000, - 547000, - 547000 - ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 0.519, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 0.07, - "sensitivity_polyp2": 0.07, - "sensitivity_polyp3": 0.22, - "sensitivity_cancer": 0.74, - "cost": 22, - "proportion_perforation": 0, - "cost_perforation": 0, - "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 - ], - "compliance_rate_given_not_prev_compliant": [ - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0 - ] - }, - "Colonoscopy": { - "proportion": 0.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 10, - "specificity": 0.86, - "sensitivity_polyp1": 0.75, - "sensitivity_polyp2": 0.85, - "sensitivity_polyp3": 0.95, - "sensitivity_cancer": 0.95, - "cost": 700, - "proportion_perforation": 0.001, - "cost_perforation": 6487, - "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 - ], - "compliance_rate_given_not_prev_compliant": [ - 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0.000296, - 0.00018, - 0.000151, - 0.000116, - 0.000112, - 0.000102, - 9.5e-05, - 8.9e-05, - 8.5e-05, - 8.5e-05, - 9e-05, - 0.000106, - 0.000134, - 0.00017, - 0.000212, - 0.000255, - 0.000298, - 0.000339, - 0.000379, - 0.00042, - 0.000464, - 0.000504, - 0.000542, - 0.000576, - 0.000609, - 0.000643, - 0.000682, - 0.000728, - 0.000781, - 0.000839, - 0.000898, - 0.000953, - 0.001, - 0.001043, - 0.001089, - 0.001143, - 0.001197, - 0.001252, - 0.001313, - 0.001388, - 0.00148, - 0.001589, - 0.001709, - 0.00184, - 0.001979, - 0.002133, - 0.002311, - 0.00252, - 0.002762, - 0.003018, - 0.003292, - 0.0036, - 0.003941, - 0.004301, - 0.004674, - 0.00505, - 0.005425, - 0.005806, - 0.006206, - 0.006644, - 0.007124, - 0.007647, - 0.008217, - 0.008842, - 0.009515, - 0.010293, - 0.011188, - 0.01228, - 0.013537, - 0.014827, - 0.01657, - 0.018235, - 0.020046, - 0.021938, - 0.024382, - 0.027026, - 0.029965, - 0.033566, - 0.037224, - 0.041748, - 0.046426, - 0.052066, - 0.059213, - 0.066359, - 0.073798, - 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0.3147, - 0.338142, - 0.361537, - 1.0 - ], - "us_age_distribution_rates": [ - 0.01237, - 0.01236, - 0.01234, - 0.01231, - 0.01208, - 0.01214, - 0.01213, - 0.01209, - 0.01211, - 0.01225, - 0.01225, - 0.01225, - 0.01264, - 0.0127, - 0.0126, - 0.01257, - 0.01262, - 0.01257, - 0.01257, - 0.01293, - 0.01318, - 0.01304, - 0.0131, - 0.01319, - 0.01332, - 0.01362, - 0.01389, - 0.01409, - 0.01443, - 0.01466, - 0.0146, - 0.01401, - 0.01366, - 0.0134, - 0.01342, - 0.01348, - 0.01304, - 0.0132, - 0.01317, - 0.01301, - 0.01323, - 0.01241, - 0.01214, - 0.012, - 0.01164, - 0.01197, - 0.01159, - 0.01174, - 0.01224, - 0.0129, - 0.01303, - 0.01232, - 0.01204, - 0.01203, - 0.01223, - 0.01294, - 0.01315, - 0.01311, - 0.01306, - 0.01319, - 0.01326, - 0.01278, - 0.01266, - 0.01248, - 0.01198, - 0.01183, - 0.01129, - 0.01081, - 0.01033, - 0.00995, - 0.00965, - 0.0093, - 0.00912, - 0.00941, - 0.00689, - 0.00671, - 0.00645, - 0.00649, - 0.00557, - 0.00499, - 0.00462, - 0.00424, - 0.00395, - 0.00352, - 0.00324, - 0.00298, - 0.00255, - 0.00234, - 0.00211, - 0.00188, - 0.00168, - 0.0014, - 0.0012, - 0.00099, - 0.00079, - 0.00064, - 0.00049, - 0.00036, - 0.00027, - 0.00019, - 0.00028 - ] -} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json index 05d0e77..3cfb63e 100644 --- a/crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.519, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc3_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc3_baseline_lower_diagnostic_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc3_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc3_baseline_lower_diagnostic_compliance/params.json index 05d0e77..3cfb63e 100644 --- a/crcsim/experiment/scenarios/fqhc3_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc3_baseline_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.519, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc3_implementation/params.json b/crcsim/experiment/scenarios/fqhc3_implementation/params.json index e45cf6b..8e3df7e 100644 --- a/crcsim/experiment/scenarios/fqhc3_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc3_implementation/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.615, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc3_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc3_implementation_Lower_repeat_compliance/params.json index f50799b..8e3df7e 100644 --- a/crcsim/experiment/scenarios/fqhc3_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc3_implementation_Lower_repeat_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.615, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, @@ -1210,6 +1210,5 @@ 0.00027, 0.00019, 0.00028 - ], - "lowered_repeat_compliance": 0.0 + ] } \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json index e45cf6b..8e3df7e 100644 --- a/crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.615, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc3_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc3_implementation_lower_diagnostic_compliance/params.json similarity index 96% rename from crcsim/experiment/scenarios/fqhc3_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc3_implementation_lower_diagnostic_compliance/params.json index e45cf6b..8e3df7e 100644 --- a/crcsim/experiment/scenarios/fqhc3_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc3_implementation_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.615, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc4_baseline/params.json b/crcsim/experiment/scenarios/fqhc4_baseline/params.json index cb19cb9..4dc3714 100644 --- a/crcsim/experiment/scenarios/fqhc4_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc4_baseline/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.278, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc4_baseline_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc4_baseline_Lower_repeat_compliance/params.json deleted file mode 100644 index cb19cb9..0000000 --- a/crcsim/experiment/scenarios/fqhc4_baseline_Lower_repeat_compliance/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - "cost_treatment_stage1_terminal": 68339, - "cost_treatment_stage2_initial": 47790, - "cost_treatment_stage2_ongoing": 3266, - "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, - "cost_treatment_stage3_ongoing": 5258, - "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, - "cost_treatment_stage4_ongoing": 26474, - "cost_treatment_stage4_terminal": 99255, - "max_ongoing_treatments": 4, - "value_loss_cancer": 0.15, - "value_life_year_ages": [ - 0, - 65, - 100 - ], - "value_life_year_dollars": [ - 217000, - 547000, - 547000 - ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 0.278, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 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0.009542, - 0.010285, - 0.011098, - 0.011952, - 0.012814, - 0.013657, - 0.014502, - 0.015384, - 0.016444, - 0.017624, - 0.018968, - 0.020586, - 0.022109, - 0.024359, - 0.026347, - 0.02881, - 0.031309, - 0.034486, - 0.038026, - 0.042286, - 0.046547, - 0.051534, - 0.057008, - 0.062923, - 0.069911, - 0.078099, - 0.086754, - 0.096549, - 0.106472, - 0.119677, - 0.134128, - 0.149846, - 0.166829, - 0.185047, - 0.204441, - 0.224919, - 0.246354, - 0.26859, - 0.291442, - 0.3147, - 0.338142, - 0.361537, - 1.0 - ], - "us_age_distribution_rates": [ - 0.01237, - 0.01236, - 0.01234, - 0.01231, - 0.01208, - 0.01214, - 0.01213, - 0.01209, - 0.01211, - 0.01225, - 0.01225, - 0.01225, - 0.01264, - 0.0127, - 0.0126, - 0.01257, - 0.01262, - 0.01257, - 0.01257, - 0.01293, - 0.01318, - 0.01304, - 0.0131, - 0.01319, - 0.01332, - 0.01362, - 0.01389, - 0.01409, - 0.01443, - 0.01466, - 0.0146, - 0.01401, - 0.01366, - 0.0134, - 0.01342, - 0.01348, - 0.01304, - 0.0132, - 0.01317, - 0.01301, - 0.01323, - 0.01241, - 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b/crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.278, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc4_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc4_baseline_lower_diagnostic_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc4_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc4_baseline_lower_diagnostic_compliance/params.json index cb19cb9..4dc3714 100644 --- a/crcsim/experiment/scenarios/fqhc4_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc4_baseline_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.278, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc4_implementation/params.json b/crcsim/experiment/scenarios/fqhc4_implementation/params.json index 2477fd6..1226a6d 100644 --- a/crcsim/experiment/scenarios/fqhc4_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc4_implementation/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.374, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc4_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc4_implementation_Lower_repeat_compliance/params.json index 37f8b30..1226a6d 100644 --- a/crcsim/experiment/scenarios/fqhc4_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc4_implementation_Lower_repeat_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.374, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, @@ -1210,6 +1210,5 @@ 0.00027, 0.00019, 0.00028 - ], - "lowered_repeat_compliance": 0.0 + ] } \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json index 2477fd6..1226a6d 100644 --- a/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.374, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc4_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc4_implementation_lower_diagnostic_compliance/params.json similarity index 96% rename from crcsim/experiment/scenarios/fqhc4_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc4_implementation_lower_diagnostic_compliance/params.json index 2477fd6..1226a6d 100644 --- a/crcsim/experiment/scenarios/fqhc4_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc4_implementation_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.374, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc5_baseline/params.json b/crcsim/experiment/scenarios/fqhc5_baseline/params.json index 0423bd7..b635666 100644 --- a/crcsim/experiment/scenarios/fqhc5_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc5_baseline/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.383, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc5_baseline_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc5_baseline_Lower_repeat_compliance/params.json deleted file mode 100644 index 0423bd7..0000000 --- a/crcsim/experiment/scenarios/fqhc5_baseline_Lower_repeat_compliance/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - "cost_treatment_stage1_terminal": 68339, - "cost_treatment_stage2_initial": 47790, - "cost_treatment_stage2_ongoing": 3266, - "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, - "cost_treatment_stage3_ongoing": 5258, - "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, - "cost_treatment_stage4_ongoing": 26474, - "cost_treatment_stage4_terminal": 99255, - "max_ongoing_treatments": 4, - "value_loss_cancer": 0.15, - "value_life_year_ages": [ - 0, - 65, - 100 - ], - "value_life_year_dollars": [ - 217000, - 547000, - 547000 - ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 0.383, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 0.07, - "sensitivity_polyp2": 0.07, - "sensitivity_polyp3": 0.22, - "sensitivity_cancer": 0.74, - "cost": 22, - "proportion_perforation": 0, - "cost_perforation": 0, - "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 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0.000296, - 0.00018, - 0.000151, - 0.000116, - 0.000112, - 0.000102, - 9.5e-05, - 8.9e-05, - 8.5e-05, - 8.5e-05, - 9e-05, - 0.000106, - 0.000134, - 0.00017, - 0.000212, - 0.000255, - 0.000298, - 0.000339, - 0.000379, - 0.00042, - 0.000464, - 0.000504, - 0.000542, - 0.000576, - 0.000609, - 0.000643, - 0.000682, - 0.000728, - 0.000781, - 0.000839, - 0.000898, - 0.000953, - 0.001, - 0.001043, - 0.001089, - 0.001143, - 0.001197, - 0.001252, - 0.001313, - 0.001388, - 0.00148, - 0.001589, - 0.001709, - 0.00184, - 0.001979, - 0.002133, - 0.002311, - 0.00252, - 0.002762, - 0.003018, - 0.003292, - 0.0036, - 0.003941, - 0.004301, - 0.004674, - 0.00505, - 0.005425, - 0.005806, - 0.006206, - 0.006644, - 0.007124, - 0.007647, - 0.008217, - 0.008842, - 0.009515, - 0.010293, - 0.011188, - 0.01228, - 0.013537, - 0.014827, - 0.01657, - 0.018235, - 0.020046, - 0.021938, - 0.024382, - 0.027026, - 0.029965, - 0.033566, - 0.037224, - 0.041748, - 0.046426, - 0.052066, - 0.059213, - 0.066359, - 0.073798, - 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0.3147, - 0.338142, - 0.361537, - 1.0 - ], - "us_age_distribution_rates": [ - 0.01237, - 0.01236, - 0.01234, - 0.01231, - 0.01208, - 0.01214, - 0.01213, - 0.01209, - 0.01211, - 0.01225, - 0.01225, - 0.01225, - 0.01264, - 0.0127, - 0.0126, - 0.01257, - 0.01262, - 0.01257, - 0.01257, - 0.01293, - 0.01318, - 0.01304, - 0.0131, - 0.01319, - 0.01332, - 0.01362, - 0.01389, - 0.01409, - 0.01443, - 0.01466, - 0.0146, - 0.01401, - 0.01366, - 0.0134, - 0.01342, - 0.01348, - 0.01304, - 0.0132, - 0.01317, - 0.01301, - 0.01323, - 0.01241, - 0.01214, - 0.012, - 0.01164, - 0.01197, - 0.01159, - 0.01174, - 0.01224, - 0.0129, - 0.01303, - 0.01232, - 0.01204, - 0.01203, - 0.01223, - 0.01294, - 0.01315, - 0.01311, - 0.01306, - 0.01319, - 0.01326, - 0.01278, - 0.01266, - 0.01248, - 0.01198, - 0.01183, - 0.01129, - 0.01081, - 0.01033, - 0.00995, - 0.00965, - 0.0093, - 0.00912, - 0.00941, - 0.00689, - 0.00671, - 0.00645, - 0.00649, - 0.00557, - 0.00499, - 0.00462, - 0.00424, - 0.00395, - 0.00352, - 0.00324, - 0.00298, - 0.00255, - 0.00234, - 0.00211, - 0.00188, - 0.00168, - 0.0014, - 0.0012, - 0.00099, - 0.00079, - 0.00064, - 0.00049, - 0.00036, - 0.00027, - 0.00019, - 0.00028 - ] -} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json index 0423bd7..b635666 100644 --- a/crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.383, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc5_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc5_baseline_lower_diagnostic_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc5_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc5_baseline_lower_diagnostic_compliance/params.json index 0423bd7..b635666 100644 --- a/crcsim/experiment/scenarios/fqhc5_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc5_baseline_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.383, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc5_implementation/params.json b/crcsim/experiment/scenarios/fqhc5_implementation/params.json index d0f464c..514e1a2 100644 --- a/crcsim/experiment/scenarios/fqhc5_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc5_implementation/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.572, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc5_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc5_implementation_Lower_repeat_compliance/params.json index ac3420e..514e1a2 100644 --- a/crcsim/experiment/scenarios/fqhc5_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc5_implementation_Lower_repeat_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.572, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, @@ -1210,6 +1210,5 @@ 0.00027, 0.00019, 0.00028 - ], - "lowered_repeat_compliance": 0.0 + ] } \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json index d0f464c..514e1a2 100644 --- a/crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.572, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc5_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc5_implementation_lower_diagnostic_compliance/params.json similarity index 96% rename from crcsim/experiment/scenarios/fqhc5_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc5_implementation_lower_diagnostic_compliance/params.json index d0f464c..514e1a2 100644 --- a/crcsim/experiment/scenarios/fqhc5_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc5_implementation_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.572, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc6_baseline/params.json b/crcsim/experiment/scenarios/fqhc6_baseline/params.json index 04c8f90..e8c1faf 100644 --- a/crcsim/experiment/scenarios/fqhc6_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc6_baseline/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.211, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc6_baseline_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc6_baseline_Lower_repeat_compliance/params.json deleted file mode 100644 index 04c8f90..0000000 --- a/crcsim/experiment/scenarios/fqhc6_baseline_Lower_repeat_compliance/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - 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- ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 0.211, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 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b/crcsim/experiment/scenarios/fqhc6_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.211, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc6_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc6_baseline_lower_diagnostic_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc6_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc6_baseline_lower_diagnostic_compliance/params.json index 04c8f90..e8c1faf 100644 --- a/crcsim/experiment/scenarios/fqhc6_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc6_baseline_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.211, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc6_implementation/params.json b/crcsim/experiment/scenarios/fqhc6_implementation/params.json index af76f65..79fc678 100644 --- a/crcsim/experiment/scenarios/fqhc6_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc6_implementation/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.392, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc6_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc6_implementation_Lower_repeat_compliance/params.json index 17c7352..79fc678 100644 --- a/crcsim/experiment/scenarios/fqhc6_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc6_implementation_Lower_repeat_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.392, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, @@ -1210,6 +1210,5 @@ 0.00027, 0.00019, 0.00028 - ], - "lowered_repeat_compliance": 0.0 + ] } \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json index af76f65..79fc678 100644 --- a/crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.392, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc6_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc6_implementation_lower_diagnostic_compliance/params.json similarity index 96% rename from crcsim/experiment/scenarios/fqhc6_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc6_implementation_lower_diagnostic_compliance/params.json index af76f65..79fc678 100644 --- a/crcsim/experiment/scenarios/fqhc6_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc6_implementation_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.392, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc7_baseline/params.json b/crcsim/experiment/scenarios/fqhc7_baseline/params.json index b45fc5e..7041a9e 100644 --- a/crcsim/experiment/scenarios/fqhc7_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc7_baseline/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.257, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc7_baseline_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc7_baseline_Lower_repeat_compliance/params.json deleted file mode 100644 index b45fc5e..0000000 --- a/crcsim/experiment/scenarios/fqhc7_baseline_Lower_repeat_compliance/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - "cost_treatment_stage1_terminal": 68339, - "cost_treatment_stage2_initial": 47790, - "cost_treatment_stage2_ongoing": 3266, - "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, - "cost_treatment_stage3_ongoing": 5258, - "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, - "cost_treatment_stage4_ongoing": 26474, - "cost_treatment_stage4_terminal": 99255, - "max_ongoing_treatments": 4, - "value_loss_cancer": 0.15, - "value_life_year_ages": [ - 0, - 65, - 100 - ], - "value_life_year_dollars": [ - 217000, - 547000, - 547000 - ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 0.257, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 0.07, - "sensitivity_polyp2": 0.07, - "sensitivity_polyp3": 0.22, - "sensitivity_cancer": 0.74, - "cost": 22, - "proportion_perforation": 0, - "cost_perforation": 0, - "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 - ], - "compliance_rate_given_not_prev_compliant": [ - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0, - 0.0 - ] - }, - "Colonoscopy": { - "proportion": 0.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 10, - "specificity": 0.86, - "sensitivity_polyp1": 0.75, - "sensitivity_polyp2": 0.85, - "sensitivity_polyp3": 0.95, - "sensitivity_cancer": 0.95, - "cost": 700, - "proportion_perforation": 0.001, - "cost_perforation": 6487, - "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 - ], - "compliance_rate_given_not_prev_compliant": [ - 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0.3147, - 0.338142, - 0.361537, - 1.0 - ], - "us_age_distribution_rates": [ - 0.01237, - 0.01236, - 0.01234, - 0.01231, - 0.01208, - 0.01214, - 0.01213, - 0.01209, - 0.01211, - 0.01225, - 0.01225, - 0.01225, - 0.01264, - 0.0127, - 0.0126, - 0.01257, - 0.01262, - 0.01257, - 0.01257, - 0.01293, - 0.01318, - 0.01304, - 0.0131, - 0.01319, - 0.01332, - 0.01362, - 0.01389, - 0.01409, - 0.01443, - 0.01466, - 0.0146, - 0.01401, - 0.01366, - 0.0134, - 0.01342, - 0.01348, - 0.01304, - 0.0132, - 0.01317, - 0.01301, - 0.01323, - 0.01241, - 0.01214, - 0.012, - 0.01164, - 0.01197, - 0.01159, - 0.01174, - 0.01224, - 0.0129, - 0.01303, - 0.01232, - 0.01204, - 0.01203, - 0.01223, - 0.01294, - 0.01315, - 0.01311, - 0.01306, - 0.01319, - 0.01326, - 0.01278, - 0.01266, - 0.01248, - 0.01198, - 0.01183, - 0.01129, - 0.01081, - 0.01033, - 0.00995, - 0.00965, - 0.0093, - 0.00912, - 0.00941, - 0.00689, - 0.00671, - 0.00645, - 0.00649, - 0.00557, - 0.00499, - 0.00462, - 0.00424, - 0.00395, - 0.00352, - 0.00324, - 0.00298, - 0.00255, - 0.00234, - 0.00211, - 0.00188, - 0.00168, - 0.0014, - 0.0012, - 0.00099, - 0.00079, - 0.00064, - 0.00049, - 0.00036, - 0.00027, - 0.00019, - 0.00028 - ] -} \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json index b45fc5e..7041a9e 100644 --- a/crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.257, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc7_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc7_baseline_lower_diagnostic_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc7_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc7_baseline_lower_diagnostic_compliance/params.json index b45fc5e..7041a9e 100644 --- a/crcsim/experiment/scenarios/fqhc7_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc7_baseline_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.257, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc7_implementation/params.json b/crcsim/experiment/scenarios/fqhc7_implementation/params.json index 8c46304..af382f9 100644 --- a/crcsim/experiment/scenarios/fqhc7_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc7_implementation/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.354, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc7_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc7_implementation_Lower_repeat_compliance/params.json index 8f708ff..af382f9 100644 --- a/crcsim/experiment/scenarios/fqhc7_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc7_implementation_Lower_repeat_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.354, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, @@ -1210,6 +1210,5 @@ 0.00027, 0.00019, 0.00028 - ], - "lowered_repeat_compliance": 0.0 + ] } \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json index 8c46304..af382f9 100644 --- a/crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.354, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc7_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc7_implementation_lower_diagnostic_compliance/params.json similarity index 96% rename from crcsim/experiment/scenarios/fqhc7_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc7_implementation_lower_diagnostic_compliance/params.json index 8c46304..af382f9 100644 --- a/crcsim/experiment/scenarios/fqhc7_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc7_implementation_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.354, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc8_baseline/params.json b/crcsim/experiment/scenarios/fqhc8_baseline/params.json index bec085c..7b29073 100644 --- a/crcsim/experiment/scenarios/fqhc8_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc8_baseline/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.19, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc8_baseline_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc8_baseline_Lower_repeat_compliance/params.json deleted file mode 100644 index bec085c..0000000 --- a/crcsim/experiment/scenarios/fqhc8_baseline_Lower_repeat_compliance/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - 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- ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 0.19, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": 50, - "routine_end": 75, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 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b/crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.19, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc8_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc8_baseline_lower_diagnostic_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc8_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc8_baseline_lower_diagnostic_compliance/params.json index bec085c..7b29073 100644 --- a/crcsim/experiment/scenarios/fqhc8_baseline_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc8_baseline_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.19, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc8_implementation/params.json b/crcsim/experiment/scenarios/fqhc8_implementation/params.json index a5a6747..37c1fed 100644 --- a/crcsim/experiment/scenarios/fqhc8_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc8_implementation/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.39, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc8_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc8_implementation_Lower_repeat_compliance/params.json index e970741..37c1fed 100644 --- a/crcsim/experiment/scenarios/fqhc8_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc8_implementation_Lower_repeat_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.39, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, @@ -1210,6 +1210,5 @@ 0.00027, 0.00019, 0.00028 - ], - "lowered_repeat_compliance": 0.0 + ] } \ No newline at end of file diff --git a/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json index a5a6747..37c1fed 100644 --- a/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.39, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc8_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json b/crcsim/experiment/scenarios/fqhc8_implementation_lower_diagnostic_compliance/params.json similarity index 96% rename from crcsim/experiment/scenarios/fqhc8_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json rename to crcsim/experiment/scenarios/fqhc8_implementation_lower_diagnostic_compliance/params.json index a5a6747..37c1fed 100644 --- a/crcsim/experiment/scenarios/fqhc8_implementation_Lower_compliance_with_diagnostic_colonoscopy/params.json +++ b/crcsim/experiment/scenarios/fqhc8_implementation_lower_diagnostic_compliance/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.39, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, + "diagnostic_compliance_rate": 0.525, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0, - 1.0 + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8, + 0.8 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/no_screening/params.json b/crcsim/experiment/scenarios/no_screening/params.json deleted file mode 100644 index 17ee0a1..0000000 --- a/crcsim/experiment/scenarios/no_screening/params.json +++ /dev/null @@ -1,1214 +0,0 @@ -{ - "max_age": 100, - "mean_duration_polyp1_polyp2": 25.5, - "mean_duration_polyp2_polyp3": 6.25, - "mean_duration_polyp2_pre": 80, - "mean_duration_polyp3_pre": 76, - "mean_duration_pre1_pre2": 3.5, - "mean_duration_pre2_pre3": 2.5, - "mean_duration_pre3_pre4": 2.5, - "mean_duration_pre1_clin1": 18, - "mean_duration_pre2_clin2": 3.9, - "mean_duration_pre3_clin3": 2.75, - "mean_duration_pre4_clin4": 1.9, - "mean_duration_clin1_dead": 135, - "mean_duration_clin2_dead": 51, - "mean_duration_clin3_dead": 19, - "mean_duration_clin4_dead": 2.7, - "proportion_survive_clin1": 0, - "proportion_survive_clin2": 0, - "proportion_survive_clin3": 0, - "proportion_survive_clin4": 0, - "cost_polypectomy": 170, - "cost_polyp_pathology": 65, - "cost_treatment_stage1_initial": 34258, - "cost_treatment_stage1_ongoing": 2685, - "cost_treatment_stage1_terminal": 68339, - "cost_treatment_stage2_initial": 47790, - "cost_treatment_stage2_ongoing": 3266, - "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 71594, - "cost_treatment_stage3_ongoing": 5258, - "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 110161, - "cost_treatment_stage4_ongoing": 26474, - "cost_treatment_stage4_terminal": 99255, - "max_ongoing_treatments": 4, - "value_loss_cancer": 0.15, - "value_life_year_ages": [ - 0, - 65, - 100 - ], - "value_life_year_dollars": [ - 217000, - 547000, - 547000 - ], - "duration_screen_skip_testing": 5, - "surveillance_freq_polyp_none": 10, - "surveillance_freq_polyp_mild": 7, - "surveillance_freq_polyp_moderate": 3, - "surveillance_freq_polyp_severe": 1, - "surveillance_freq_cancer_first": 1, - "surveillance_freq_cancer_second": 3, - "surveillance_freq_cancer_rest": 5, - "surveillance_end_age": 85, - "use_conditional_compliance": true, - "initial_compliance_rate": 1.0, - "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 1.0, - "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, - "lesion_risk_beta": 2.45, - "lesion_incidence_ages": [ - 0, - 20, - 30, - 40, - 45, - 50, - 55, - 60, - 65, - 70, - 75, - 85, - 100 - ], - "lesion_incidence_rates": [ - 0.0, - 0.002, - 0.002, - 0.015, - 0.02, - 0.025, - 0.027, - 0.027, - 0.027, - 0.014, - 0.011, - 0.011, - 0.011 - ], - "tests": { - "FIT": { - "proportion": 1.0, - "routine_start": -1, - "routine_end": -1, - "routine_freq": 1, - "specificity": 0.97, - "sensitivity_polyp1": 0.07, - "sensitivity_polyp2": 0.07, - "sensitivity_polyp3": 0.22, - "sensitivity_cancer": 0.74, - "cost": 22, - "proportion_perforation": 0, - "cost_perforation": 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0.000151, - 0.000139, - 0.000133, - 0.000133, - 0.00014, - 0.000154, - 0.000174, - 0.000201, - 0.000231, - 0.000267, - 0.000313, - 0.000372, - 0.000438, - 0.000508, - 0.000576, - 0.000637, - 0.000688, - 0.000731, - 0.000772, - 0.000815, - 0.000859, - 0.000908, - 0.000965, - 0.00103, - 0.001105, - 0.001186, - 0.001269, - 0.001353, - 0.00144, - 0.001536, - 0.001637, - 0.00175, - 0.00188, - 0.002033, - 0.002206, - 0.002383, - 0.002553, - 0.002721, - 0.002895, - 0.003099, - 0.003347, - 0.003655, - 0.004018, - 0.0044, - 0.004802, - 0.005266, - 0.005797, - 0.006375, - 0.006974, - 0.007576, - 0.008184, - 0.008803, - 0.009446, - 0.010126, - 0.010845, - 0.011602, - 0.012397, - 0.013231, - 0.014149, - 0.015137, - 0.016142, - 0.017121, - 0.018187, - 0.019264, - 0.020677, - 0.022638, - 0.024656, - 0.026985, - 0.029625, - 0.032101, - 0.035679, - 0.039136, - 0.042432, - 0.047008, - 0.051308, - 0.055972, - 0.061447, - 0.067875, - 0.073825, - 0.081779, - 0.090536, - 0.100072, - 0.110418, - 0.121605, - 0.133654, - 0.146574, - 0.160368, - 0.175024, - 0.190515, - 0.2068, - 0.223822, - 0.241511, - 0.259776, - 1.0 - ], - "death_rate_black_male_ages": [ - 0, - 1, - 2, - 3, - 4, - 5, - 6, - 7, - 8, - 9, - 10, - 11, - 12, - 13, - 14, - 15, - 16, - 17, - 18, - 19, - 20, - 21, - 22, - 23, - 24, - 25, - 26, - 27, - 28, - 29, - 30, - 31, - 32, - 33, - 34, - 35, - 36, - 37, - 38, - 39, - 40, - 41, - 42, - 43, - 44, - 45, - 46, - 47, - 48, - 49, - 50, - 51, - 52, - 53, - 54, - 55, - 56, - 57, - 58, - 59, - 60, - 61, - 62, - 63, - 64, - 65, - 66, - 67, - 68, - 69, - 70, - 71, - 72, - 73, - 74, - 75, - 76, - 77, - 78, - 79, - 80, - 81, - 82, - 83, - 84, - 85, - 86, - 87, - 88, - 89, - 90, - 91, - 92, - 93, - 94, - 95, - 96, - 97, - 98, - 99, - 100 - ], - "death_rate_black_male_rates": [ - 0.011882, - 0.000622, - 0.000406, - 0.000347, - 0.000231, - 0.000231, - 0.000211, - 0.000192, - 0.000169, - 0.000142, - 0.000125, - 0.00014, - 0.000211, - 0.000352, - 0.000546, - 0.000757, - 0.000965, - 0.001172, - 0.00137, - 0.001554, - 0.001736, - 0.001909, - 0.002051, - 0.002154, - 0.002225, - 0.002287, - 0.002346, - 0.002397, - 0.002444, - 0.002494, - 0.002543, - 0.002598, - 0.002675, - 0.002779, - 0.002899, - 0.003034, - 0.003172, - 0.003292, - 0.003391, - 0.003483, - 0.003593, - 0.003742, - 0.003932, - 0.004165, - 0.004434, - 0.004731, - 0.005061, - 0.005438, - 0.005874, - 0.006376, - 0.006905, - 0.007485, - 0.008192, - 0.00905, - 0.01002, - 0.011026, - 0.012041, - 0.013122, - 0.014298, - 0.015581, - 0.016979, - 0.018443, - 0.01992, - 0.021354, - 0.02276, - 0.024279, - 0.025931, - 0.027551, - 0.029041, - 0.030501, - 0.031843, - 0.034142, - 0.036113, - 0.039043, - 0.041873, - 0.044907, - 0.048772, - 0.052158, - 0.057218, - 0.062038, - 0.066654, - 0.072113, - 0.079691, - 0.087605, - 0.09403, - 0.100906, - 0.110227, - 0.120226, - 0.130918, - 0.142314, - 0.154416, - 0.167219, - 0.180709, - 0.194863, - 0.209647, - 0.225017, - 0.240921, - 0.257294, - 0.274063, - 0.291147, - 1.0 - ], - "death_rate_white_female_ages": [ - 0, - 1, - 2, - 3, - 4, - 5, - 6, - 7, - 8, - 9, - 10, - 11, - 12, - 13, - 14, - 15, - 16, - 17, - 18, - 19, - 20, - 21, - 22, - 23, - 24, - 25, - 26, - 27, - 28, - 29, - 30, - 31, - 32, - 33, - 34, - 35, - 36, - 37, - 38, - 39, - 40, - 41, - 42, - 43, - 44, - 45, - 46, - 47, - 48, - 49, - 50, - 51, - 52, - 53, - 54, - 55, - 56, - 57, - 58, - 59, - 60, - 61, - 62, - 63, - 64, - 65, - 66, - 67, - 68, - 69, - 70, - 71, - 72, - 73, - 74, - 75, - 76, - 77, - 78, - 79, - 80, - 81, - 82, - 83, - 84, - 85, - 86, - 87, - 88, - 89, - 90, - 91, - 92, - 93, - 94, - 95, - 96, - 97, - 98, - 99, - 100 - ], - "death_rate_white_female_rates": [ - 0.004376, - 0.000296, - 0.00018, - 0.000151, - 0.000116, - 0.000112, - 0.000102, - 9.5e-05, - 8.9e-05, - 8.5e-05, - 8.5e-05, - 9e-05, - 0.000106, - 0.000134, - 0.00017, - 0.000212, - 0.000255, - 0.000298, - 0.000339, - 0.000379, - 0.00042, - 0.000464, - 0.000504, - 0.000542, - 0.000576, - 0.000609, - 0.000643, - 0.000682, - 0.000728, - 0.000781, - 0.000839, - 0.000898, - 0.000953, - 0.001, - 0.001043, - 0.001089, - 0.001143, - 0.001197, - 0.001252, - 0.001313, - 0.001388, - 0.00148, - 0.001589, - 0.001709, - 0.00184, - 0.001979, - 0.002133, - 0.002311, - 0.00252, - 0.002762, - 0.003018, - 0.003292, - 0.0036, - 0.003941, - 0.004301, - 0.004674, - 0.00505, - 0.005425, - 0.005806, - 0.006206, - 0.006644, - 0.007124, - 0.007647, - 0.008217, - 0.008842, - 0.009515, - 0.010293, - 0.011188, - 0.01228, - 0.013537, - 0.014827, - 0.01657, - 0.018235, - 0.020046, - 0.021938, - 0.024382, - 0.027026, - 0.029965, - 0.033566, - 0.037224, - 0.041748, - 0.046426, - 0.052066, - 0.059213, - 0.066359, - 0.073798, - 0.081793, - 0.092586, - 0.104549, - 0.117741, - 0.132206, - 0.147969, - 0.165031, - 0.183365, - 0.202911, - 0.223578, - 0.245236, - 0.267725, - 0.290853, - 0.314404, - 1.0 - ], - "death_rate_white_male_ages": [ - 0, - 1, - 2, - 3, - 4, - 5, - 6, - 7, - 8, - 9, - 10, - 11, - 12, - 13, - 14, - 15, - 16, - 17, - 18, - 19, - 20, - 21, - 22, - 23, - 24, - 25, - 26, - 27, - 28, - 29, - 30, - 31, - 32, - 33, - 34, - 35, - 36, - 37, - 38, - 39, - 40, - 41, - 42, - 43, - 44, - 45, - 46, - 47, - 48, - 49, - 50, - 51, - 52, - 53, - 54, - 55, - 56, - 57, - 58, - 59, - 60, - 61, - 62, - 63, - 64, - 65, - 66, - 67, - 68, - 69, - 70, - 71, - 72, - 73, - 74, - 75, - 76, - 77, - 78, - 79, - 80, - 81, - 82, - 83, - 84, - 85, - 86, - 87, - 88, - 89, - 90, - 91, - 92, - 93, - 94, - 95, - 96, - 97, - 98, - 99, - 100 - ], - "death_rate_white_male_rates": [ - 0.005273, - 0.000389, - 0.000273, - 0.000199, - 0.000147, - 0.000143, - 0.000126, - 0.000112, - 0.0001, - 9.1e-05, - 9e-05, - 0.000105, - 0.000145, - 0.000215, - 0.000309, - 0.000412, - 0.00052, - 0.000642, - 0.000778, - 0.000921, - 0.001068, - 0.001209, - 0.00133, - 0.001424, - 0.001497, - 0.001561, - 0.001624, - 0.001682, - 0.001737, - 0.001792, - 0.001847, - 0.0019, - 0.001952, - 0.002003, - 0.002053, - 0.002111, - 0.002174, - 0.002233, - 0.002285, - 0.00234, - 0.002413, - 0.002516, - 0.002649, - 0.002811, - 0.002999, - 0.003203, - 0.003433, - 0.003709, - 0.004047, - 0.004445, - 0.004874, - 0.005331, - 0.005844, - 0.006408, - 0.007003, - 0.007607, - 0.008219, - 0.008857, - 0.009542, - 0.010285, - 0.011098, - 0.011952, - 0.012814, - 0.013657, - 0.014502, - 0.015384, - 0.016444, - 0.017624, - 0.018968, - 0.020586, - 0.022109, - 0.024359, - 0.026347, - 0.02881, - 0.031309, - 0.034486, - 0.038026, - 0.042286, - 0.046547, - 0.051534, - 0.057008, - 0.062923, - 0.069911, - 0.078099, - 0.086754, - 0.096549, - 0.106472, - 0.119677, - 0.134128, - 0.149846, - 0.166829, - 0.185047, - 0.204441, - 0.224919, - 0.246354, - 0.26859, - 0.291442, - 0.3147, - 0.338142, - 0.361537, - 1.0 - ], - "us_age_distribution_rates": [ - 0.01237, - 0.01236, - 0.01234, - 0.01231, - 0.01208, - 0.01214, - 0.01213, - 0.01209, - 0.01211, - 0.01225, - 0.01225, - 0.01225, - 0.01264, - 0.0127, - 0.0126, - 0.01257, - 0.01262, - 0.01257, - 0.01257, - 0.01293, - 0.01318, - 0.01304, - 0.0131, - 0.01319, - 0.01332, - 0.01362, - 0.01389, - 0.01409, - 0.01443, - 0.01466, - 0.0146, - 0.01401, - 0.01366, - 0.0134, - 0.01342, - 0.01348, - 0.01304, - 0.0132, - 0.01317, - 0.01301, - 0.01323, - 0.01241, - 0.01214, - 0.012, - 0.01164, - 0.01197, - 0.01159, - 0.01174, - 0.01224, - 0.0129, - 0.01303, - 0.01232, - 0.01204, - 0.01203, - 0.01223, - 0.01294, - 0.01315, - 0.01311, - 0.01306, - 0.01319, - 0.01326, - 0.01278, - 0.01266, - 0.01248, - 0.01198, - 0.01183, - 0.01129, - 0.01081, - 0.01033, - 0.00995, - 0.00965, - 0.0093, - 0.00912, - 0.00941, - 0.00689, - 0.00671, - 0.00645, - 0.00649, - 0.00557, - 0.00499, - 0.00462, - 0.00424, - 0.00395, - 0.00352, - 0.00324, - 0.00298, - 0.00255, - 0.00234, - 0.00211, - 0.00188, - 0.00168, - 0.0014, - 0.0012, - 0.00099, - 0.00079, - 0.00064, - 0.00049, - 0.00036, - 0.00027, - 0.00019, - 0.00028 - ] -} \ No newline at end of file diff --git a/crcsim/experiment/summarize.py b/crcsim/experiment/summarize.py index 156c03b..68a7f03 100644 --- a/crcsim/experiment/summarize.py +++ b/crcsim/experiment/summarize.py @@ -5,7 +5,7 @@ import s3fs # noqa: F401 -S3_BUCKET_NAME = "crcsim-exp-crccp-replication" +S3_BUCKET_NAME = "crcsim-exp-crccp-sensitivity01" def main() -> None: @@ -67,7 +67,7 @@ def combine_run_results() -> pd.DataFrame: iteration_name = f"{iteration:03}" print(f"Fetching results for {scenario}, iteration {iteration_name}") - + df = pd.read_csv( f"s3://{S3_BUCKET_NAME}/scenarios/{scenario}/results_{iteration_name}.csv" ) diff --git a/crcsim/experiment/summary/combined.csv b/crcsim/experiment/summary/combined.csv deleted file mode 100644 index 3e1df7a..0000000 --- a/crcsim/experiment/summary/combined.csv +++ /dev/null @@ -1,1601 +0,0 @@ -n,n_unscreened_undiagnosed_40yos,polyp,polyp_per_1k_40yo,crc,crc_per_1k_40yo,clin_crc,clin_crc_per_1k_40yo,deadcrc,deadcrc_per_1k_40yo,lifeexp,lifeexp_if_unscreened_undiagnosed_at_40,discounted_lifeexp,discounted_lifeexp_if_unscreened_undiagnosed_at_40,lifeobs,lifeobs_if_unscreened_undiagnosed_at_40,discounted_lifeobs,discounted_lifeobs_if_unscreened_undiagnosed_at_40,lifelost,lifelost_per_1k_40yo,discounted_lifelost,discounted_lifelost_per_1k_40yo,cost_routine,discounted_cost_routine,cost_routine_per_1k_40yo,discounted_cost_routine_per_1k_40yo,cost_diagnostic,discounted_cost_diagnostic,cost_diagnostic_per_1k_40yo,discounted_cost_diagnostic_per_1k_40yo,cost_surveillance,discounted_cost_surveillance,cost_surveillance_per_1k_40yo,discounted_cost_surveillance_per_1k_40yo,cost_treatment_initial,discounted_cost_treatment_initial,cost_treatment_initial_per_1k_40yo,discounted_cost_treatment_initial_per_1k_40yo,cost_treatment_ongoing,discounted_cost_treatment_ongoing,cost_treatment_ongoing_per_1k_40yo,discounted_cost_treatment_ongoing_per_1k_40yo,cost_treatment_terminal,discounted_cost_treatment_terminal,cost_treatment_terminal_per_1k_40yo,discounted_cost_treatment_terminal_per_1k_40yo,prob_polyp,FIT_adopted,Colonoscopy_adopted,FIT_performed_routine,FIT_performed_routine_per_1k_40yo,Colonoscopy_performed_routine,Colonoscopy_performed_routine_per_1k_40yo,FIT_performed_diagnostic,FIT_performed_diagnostic_per_1k_40yo,Colonoscopy_performed_diagnostic,Colonoscopy_performed_diagnostic_per_1k_40yo,FIT_performed_surveillance,FIT_performed_surveillance_per_1k_40yo,Colonoscopy_performed_surveillance,Colonoscopy_performed_surveillance_per_1k_40yo,FIT_noncompliant_routine,Colonoscopy_noncompliant_routine,FIT_noncompliant_routine_50,Colonoscopy_noncompliant_routine_50,FIT_noncompliant_diagnostic,Colonoscopy_noncompliant_diagnostic,FIT_noncompliant_surveillance,Colonoscopy_noncompliant_surveillance,FIT_perforations,FIT_perforations_per_1k_40yo,Colonoscopy_perforations,Colonoscopy_perforations_per_1k_40yo,FIT_test_fatalities,FIT_test_fatalities_per_1k_40yo,Colonoscopy_test_fatalities,Colonoscopy_test_fatalities_per_1k_40yo,prob_crc,prob_crc_given_polyp,prob_dead_crc_given_crc,prob_dead_crc,prob_crc_from_medium_polyp,prob_crc_from_large_polyp,time_polyp_to_pre,time_pre_to_clin,crc_onset_proportion_stage2,crc_onset_proportion_stage1,crc_onset_proportion_stage4,crc_onset_proportion_stage3,time_pre_to_dead,time_clin_to_dead,crc_mortality_rate,polyp_prevalence_rate,crc_incidence_rate,crc_incidence_stage1_rate,crc_incidence_stage2_rate,crc_incidence_stage3_rate,crc_incidence_stage4_rate,crc_survival_rate,crc_survival_stage1_rate,crc_survival_stage2_rate,crc_survival_stage3_rate,crc_survival_stage4_rate,crc_survival_rate_20_64,crc_survival_stage1_rate_20_64,crc_survival_stage2_rate_20_64,crc_survival_stage3_rate_20_64,crc_survival_stage4_rate_20_64,crc_survival_rate_65_100,crc_survival_stage1_rate_65_100,crc_survival_stage2_rate_65_100,crc_survival_stage3_rate_65_100,crc_survival_stage4_rate_65_100,polyp_prevalence_rate_0,polyp_prevalence_rate_1,polyp_prevalence_rate_2,polyp_prevalence_rate_3,polyp_prevalence_rate_4,polyp_prevalence_rate_5,polyp_prevalence_rate_6,polyp_prevalence_rate_7,polyp_prevalence_rate_8,polyp_prevalence_rate_9,polyp_prevalence_rate_10,polyp_prevalence_rate_11,polyp_prevalence_rate_12,polyp_prevalence_rate_13,polyp_prevalence_rate_14,polyp_prevalence_rate_15,polyp_prevalence_rate_16,polyp_prevalence_rate_17,polyp_prevalence_rate_18,polyp_prevalence_rate_19,polyp_prevalence_rate_20,polyp_prevalence_rate_21,polyp_prevalence_rate_22,polyp_prevalence_rate_23,polyp_prevalence_rate_24,polyp_prevalence_rate_25,polyp_prevalence_rate_26,polyp_prevalence_rate_27,polyp_prevalence_rate_28,polyp_prevalence_rate_29,polyp_prevalence_rate_30,polyp_prevalence_rate_31,polyp_prevalence_rate_32,polyp_prevalence_rate_33,polyp_prevalence_rate_34,polyp_prevalence_rate_35,polyp_prevalence_rate_36,polyp_prevalence_rate_37,polyp_prevalence_rate_38,polyp_prevalence_rate_39,polyp_prevalence_rate_40,polyp_prevalence_rate_41,polyp_prevalence_rate_42,polyp_prevalence_rate_43,polyp_prevalence_rate_44,polyp_prevalence_rate_45,polyp_prevalence_rate_46,polyp_prevalence_rate_47,polyp_prevalence_rate_48,polyp_prevalence_rate_49,polyp_prevalence_rate_50,polyp_prevalence_rate_51,polyp_prevalence_rate_52,polyp_prevalence_rate_53,polyp_prevalence_rate_54,polyp_prevalence_rate_55,polyp_prevalence_rate_56,polyp_prevalence_rate_57,polyp_prevalence_rate_58,polyp_prevalence_rate_59,polyp_prevalence_rate_60,polyp_prevalence_rate_61,polyp_prevalence_rate_62,polyp_prevalence_rate_63,polyp_prevalence_rate_64,polyp_prevalence_rate_65,polyp_prevalence_rate_66,polyp_prevalence_rate_67,polyp_prevalence_rate_68,polyp_prevalence_rate_69,polyp_prevalence_rate_70,polyp_prevalence_rate_71,polyp_prevalence_rate_72,polyp_prevalence_rate_73,polyp_prevalence_rate_74,polyp_prevalence_rate_75,polyp_prevalence_rate_76,polyp_prevalence_rate_77,polyp_prevalence_rate_78,polyp_prevalence_rate_79,polyp_prevalence_rate_80,polyp_prevalence_rate_81,polyp_prevalence_rate_82,polyp_prevalence_rate_83,polyp_prevalence_rate_84,polyp_prevalence_rate_85,polyp_prevalence_rate_86,polyp_prevalence_rate_87,polyp_prevalence_rate_88,polyp_prevalence_rate_89,polyp_prevalence_rate_90,polyp_prevalence_rate_91,polyp_prevalence_rate_92,polyp_prevalence_rate_93,polyp_prevalence_rate_94,polyp_prevalence_rate_95,polyp_prevalence_rate_96,polyp_prevalence_rate_97,polyp_prevalence_rate_98,polyp_prevalence_rate_99,polyp_prevalence_rate_100,crc_incidence_15_39,crc_incidence_40_64,crc_incidence_65_74,crc_incidence_75_100,scenario,iteration 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-100000,95780,43790,413.8651075381081,6335,64.93004802672792,4902,50.553351430361246,1953,19.97285445813322,77.36330519993753,79.69793059021613,66.21135634370845,68.06226379677624,77.12242123963387,79.4608268488482,66.10755760692,67.96328885068532,0.2408839603036625,237.10374136793175,0.1037987367884483,98.9749460909195,117.18102,87.19299526061486,122343.93401545208,91034.65782064613,237.33781,167.7807881382446,247316.51701816663,174694.86128444836,256.71322,141.59901621353265,265343.35978283564,145652.2566207582,3269.93568,1733.554864690643,3371063.6562956776,1766990.9737843417,895.03408,463.2966872585583,918845.145124243,468085.70396592014,1712.78419,830.7610853188833,1752631.8960116934,834893.5616434711,0.38002,100000,0,532641,5561.087909793277,0,0.0,0,0.0,28197,293.725203591564,0,0.0,32441,335.08039256629775,1361120,0,59746,0,0,0,0,0,64,0.668197953643767,0,0.0,0,0.0,0,0.0,0.06335,0.16670175253934,0.3082872928176796,0.01953,0.3390752493200362,0.6609247506799637,24.337738148041723,4.38574766715463,0.3215014279885761,0.2356181150550795,0.2168502651978784,0.2260301917584659,11.47726966871184,6.017154476841672,20.78970855467272,12417.533831265811,55.959476638588654,14.004196718601008,18.066481232049323,12.385599516278695,11.503199171659636,0.5783353733170135,0.7974025974025974,0.7106598984771574,0.5974729241877257,0.1241768579492003,0.7472766884531591,0.9295454545454546,0.875,0.7389558232931727,0.1594827586206896,0.512340425531915,0.7160839160839161,0.64375,0.5564610011641443,0.1143200962695547,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022787810040815,0.0048058400081111,0.0069216092233995,0.0088382299158844,0.0111452337855152,0.0130305097168918,0.0152309103884188,0.0175048227572902,0.0198266699370452,0.0219722864686738,0.0241052761038002,0.0262344887045951,0.0280899454035102,0.0299947486022014,0.0321609076843733,0.0339942757359399,0.0360691368246739,0.0381544841886988,0.040371928730975,0.0423997001936249,0.057238565331274,0.0707921102721245,0.0843301498107708,0.0975181591699866,0.1098451712180777,0.1247251585623678,0.1402604564350555,0.1542906397650364,0.1678857057435426,0.1806837551860547,0.1962336068221461,0.2063143549364021,0.2158636284571229,0.2252416779668431,0.2337456530351719,0.2428554015269882,0.2518021737674917,0.2605747824327059,0.2675763969237051,0.2751955294467919,0.2823436885568226,0.288681253142797,0.2947218934911242,0.3011902336118136,0.3074008864064113,0.3118639891585561,0.3163238479161711,0.3213808208014465,0.3246080082933782,0.3281640093523374,0.3276560795982389,0.3269466184339023,0.3253129228687415,0.325189273536381,0.3242235101798187,0.3229596988891949,0.3220473063839886,0.3230660787174401,0.3240797650754626,0.3248359954363947,0.3263059352181239,0.3267316957586288,0.32735275623559,0.3273837482386096,0.3286356749476924,0.3293765456202004,0.3307508939213349,0.3347642174526085,0.3386108094854461,0.339127673929436,0.3429484253765404,0.3448750529436679,0.3492739108662994,0.3502058240585455,0.3503160675535428,0.3519226176259852,0.3559975331483194,0.3547928513403737,0.3586380128384036,0.3565351894818252,0.0,2.377991984447664,60.24758477808752,184.314693266051,260.1055003410715,fqhc7_implementation,90 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-100000,95774,44353,419.3309248856684,6065,62.07321402468311,4772,49.2931275711571,1889,19.29542464551966,77.30560573819784,79.63942837525201,66.18173080579547,68.03073762920748,77.06746615533194,79.40355499268024,66.07791824071937,67.93069711103314,0.2381395828658981,235.87338257176785,0.1038125650760974,100.0405181743389,127.69724,95.0777464175143,133331.84371541336,99273.02442992284,253.90569,180.0240655297154,264719.3288366362,187577.6990934026,265.56913,146.53420727854743,275097.1871280306,151093.5193821341,3170.42179,1683.6431879566708,3274904.9846513667,1722522.7075789582,861.74004,443.5130578860193,889511.1199281643,452829.9934074166,1654.77547,810.1192432917652,1691774.8553887275,814980.2745128606,0.38014,100000,0,580442,6060.538350700607,0,0.0,0,0.0,30214,314.9288951072316,0,0.0,33569,347.5473510556101,1290331,0,56706,0,0,0,0,0,61,0.6369160732557897,0,0.0,0,0.0,0,0.0,0.06065,0.1595464828747303,0.3114591920857378,0.01889,0.343152616734566,0.656847383265434,24.62102537233922,4.3431186620468365,0.3327745180217938,0.2355406538139145,0.2160519698239731,0.2156328583403185,11.394012409199648,6.058264259645909,20.26978529110997,12254.106593406928,54.38306007904965,13.610416702402905,17.973812078020234,11.431247590370914,11.367583708255593,0.5712489522212909,0.8033807829181495,0.6939546599496221,0.5889212827988338,0.1115421920465567,0.7325925925925926,0.9453302961275628,0.8466981132075472,0.7622950819672131,0.1193415637860082,0.5075978959672706,0.7124087591240876,0.6383161512027491,0.535031847133758,0.1091370558375634,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022984083269207,0.0046099757849623,0.0067544268878927,0.0088935815955653,0.0109886758696403,0.0131600374547083,0.0156031838240539,0.0175313278092983,0.0195681718320509,0.0217159932866674,0.0241770179969663,0.0262823012663943,0.0285394113232376,0.0305776697529274,0.0326727259597032,0.0347464018928161,0.0367325810125271,0.0388422035480859,0.0408311763910978,0.0428855586682357,0.0572997119358744,0.0709443200602624,0.0839321493385924,0.0973132131026867,0.1091380728430731,0.1246099658356515,0.1402073451543416,0.1538027629366312,0.1672683770908547,0.1792985879552691,0.1945812011850256,0.2039069264069264,0.213747932805292,0.222567650407216,0.2311234494458765,0.2400621118012422,0.2491871780834162,0.2582338364496508,0.2647346289351062,0.2725457341565864,0.279249831930825,0.2852789855497087,0.2921139088871229,0.298182822690095,0.3030992842187271,0.3071332502498674,0.3121356850062051,0.31689997195237,0.3194549091948349,0.3236696421476439,0.3226019994596055,0.3213832136940917,0.3195134341837887,0.3183885734152277,0.3170186779469153,0.3148716218288904,0.3126742270653826,0.3132482632901414,0.3136058259397918,0.314456969046341,0.3154257816167496,0.3164659748078903,0.3177717163239614,0.3184429986361705,0.3193152035393974,0.3217266562336985,0.322493379274995,0.3262172048435923,0.3294432887917357,0.331873033573619,0.3355848660490165,0.339859840582036,0.3429982273993416,0.3450854700854701,0.3470560527555346,0.3552003816793893,0.3550881534178781,0.3587136929460581,0.3616298811544992,0.3660714285714285,0.0,2.1188145383000845,59.57141040314762,172.16499456414073,258.9488167724795,fqhc8_implementation,22 -100000,95667,44578,421.9636865376776,6082,62.33079327249731,4776,49.2646367085829,1860,18.992965181305987,77.3345703778802,79.74098912213049,66.17493331886145,68.08307214095639,77.10118775409477,79.51086564792065,66.07379256037308,67.98631742983711,0.233382623785431,230.12347420983303,0.1011407584883699,96.75471111927436,127.62926,94.9947702674048,133409.9114637231,99297.3232853594,256.59846,182.62331119072832,267712.33549708885,190386.665402624,271.31136,150.09571802521808,280661.24159846135,154393.38275212338,3190.85052,1697.0842862841391,3294788.8613628526,1733366.182993235,886.74271,455.44133635343104,912832.0319441396,461995.9300003461,1628.73642,795.7876226281943,1665426.887014331,798462.9729365208,0.38024,100000,0,580133,6064.086884714688,0,0.0,0,0.0,30555,318.68878505649803,0,0.0,34274,354.38552478911225,1289785,0,56485,0,0,0,0,0,56,0.5749108888122341,0,0.0,0,0.0,0,0.0,0.06082,0.1599516095097833,0.3058204537980927,0.0186,0.3341213553979511,0.6658786446020488,24.37256076535963,4.324847552449599,0.3251675041876047,0.2340871021775544,0.2116834170854271,0.2290619765494137,11.567270318490207,6.192446340325435,19.827831641017266,12254.579108787888,54.67978078927104,13.652144600550828,17.767592410639914,12.240275146914014,11.019768631166276,0.586892797319933,0.7960644007155635,0.7160334835801674,0.5959780621572212,0.1473788328387734,0.7426099495313626,0.920704845814978,0.8471910112359551,0.7323420074349443,0.1735159817351598,0.5231631749778696,0.7108433734939759,0.6633574007220217,0.5515151515151515,0.1401515151515151,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024521228087952,0.0047466428658363,0.0069234361358698,0.0093005763307955,0.0116939423546653,0.0140735984999031,0.0159901222473928,0.0183586526771758,0.0207144172343951,0.0226052933464437,0.0246476706258846,0.0266544778495639,0.0284370916797843,0.0304610374889223,0.0327479584146354,0.0346065138022691,0.0366153112923112,0.0387070656743374,0.0410534308269972,0.043082600175124,0.0580117423371847,0.072349960212757,0.0855814246425797,0.0980744949494949,0.1100890332925439,0.1250661361664303,0.140372855444199,0.1546901297428577,0.167773322641005,0.1807759194452197,0.1952198110358514,0.2046057691266153,0.2139226591495336,0.2232330530740935,0.2307624533309838,0.2402694527848255,0.2491211231766793,0.2576239918107472,0.2650159436242524,0.2720690998235847,0.279199740806739,0.2854234432405869,0.2913712912884481,0.297193419382648,0.3020209989682588,0.3061958677787771,0.3114288218135383,0.316005855024502,0.3194320287094977,0.3224682625564148,0.3217689822294022,0.3200715120676614,0.3196530003936786,0.3192091210852937,0.3183375606283095,0.3160011622750003,0.3139397192794101,0.3148739619674708,0.314524235454468,0.3154216437867712,0.3154349859681946,0.3157853212094913,0.3163599908101673,0.3173392223783711,0.3167746580273578,0.3164925411923697,0.3166283133043552,0.3204641681041242,0.323895413870246,0.3269886588944404,0.3295910916392844,0.3319157984265362,0.3351551702475185,0.3329794494577993,0.3355158544570199,0.3380678483390069,0.3412172341066586,0.3402473075388911,0.3430578065910318,0.3524933384088313,0.0,2.486625877484613,60.86705629742786,173.37023099184697,253.94923582920123,fqhc8_implementation,23 -100000,95620,44325,419.1591717213972,6136,62.82158544237607,4838,49.86404517883288,1910,19.52520393223175,77.28040018624887,79.71369473125834,66.13984935772031,68.07170037234022,77.0401021229957,79.47756118904682,66.03523261233313,67.97214935460364,0.2402980632531637,236.13354221151891,0.104616745387176,99.55101773657304,127.8684,95.12776766267056,133725.58042250574,99485.22031235156,254.39956,180.29323513895037,265515.7498431291,188014.88719823293,269.03348,148.22562718837804,277749.7176322945,152024.23484343066,3250.44861,1717.4196042292672,3351384.14557624,1748242.4155126929,901.64458,466.955973050946,929151.4013804644,474551.31044859486,1683.92732,822.5267093748574,1723142.4074461411,826146.609262557,0.3776,100000,0,581220,6078.435473750261,0,0.0,0,0.0,30298,316.10541727672035,0,0.0,33907,349.75946454716586,1291084,0,56662,0,0,0,0,0,62,0.6483999163354947,0,0.0,2,0.020916126333403,0,0.0,0.06136,0.1625,0.311277705345502,0.0191,0.3272104607721046,0.6727895392278954,24.50747212576968,4.369521084194864,0.319346837536172,0.2346010748243075,0.2252997106242248,0.2207523770152955,11.239482325472864,5.80325545498363,20.319008580162212,12289.586598244292,55.05412120535176,13.748551797454455,17.52975692670139,11.845524324709658,11.930288156486272,0.5525010334849111,0.7814977973568282,0.6802588996763754,0.5720973782771536,0.1137614678899082,0.7155688622754491,0.8997668997668997,0.8304668304668305,0.7755102040816326,0.1647058823529411,0.4902912621359223,0.7096317280453258,0.6265377855887522,0.511543134872418,0.0982035928143712,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0026152801289393,0.0047582813371886,0.007028020677818,0.0095366877802291,0.0119907982329349,0.014125416577491,0.016508856419884,0.0186140596426345,0.0209205020920502,0.0231466775961883,0.0253950338600451,0.0274363927822762,0.0294995574037095,0.0314056233181082,0.0332324724009377,0.0351165725397712,0.0374762857527912,0.0396193879458999,0.0414632877140032,0.043557168784029,0.0584982963690712,0.0723181832465668,0.0852239307621208,0.0979411300089516,0.1103122063497091,0.1262055750235557,0.1400016993075321,0.1537436575278216,0.1665579450545925,0.1792696936836341,0.1938450921403077,0.2027969755400047,0.2120723644799756,0.2205255720717266,0.2292929070356741,0.2391277811685069,0.248259368119894,0.2561936936936937,0.26418093464735,0.2714611584268503,0.2782821148190176,0.2850853570006791,0.2903267834511838,0.2961559220389805,0.3010803650637403,0.3060529820926446,0.3110521175085777,0.3165430087684691,0.3205835859960092,0.3245424051134413,0.3236836075957897,0.3224250775060282,0.3214154697068036,0.319966425956209,0.3185834126606378,0.3174430371983194,0.31656420332108,0.3165785411671976,0.3164171443237231,0.317008698137134,0.3192413547771058,0.3204477700341553,0.3213561165373434,0.3219971864323515,0.323258491652274,0.3254119055675577,0.3267020461446774,0.3310457209112845,0.3336846543001686,0.3348852015439099,0.3405561409134637,0.3441451053614297,0.3476148409893993,0.3508396946564885,0.3554965379872901,0.3567923399162178,0.3591134531928084,0.3635804997951659,0.3703290574456219,0.3655669321198331,0.0,2.768848225047666,58.20088054254631,177.4575873884569,264.0893191099518,fqhc8_implementation,24 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-100000,95749,44898,425.0801574951175,6208,63.52024564225214,4892,50.61149463701971,1951,20.06287271929733,77.34480713189683,79.70303624920945,66.19703327670871,68.06539599453643,77.0964078496049,79.45328382828964,66.088246599476,67.95854839480234,0.2483992822919276,249.7524209198048,0.1087866772327146,106.8475997340954,128.77898,95.83478202275468,134496.1931717303,100089.3607481589,258.19812,183.04769234453585,269295.88820770977,190808.9821768748,268.52063,147.99763670951873,278356.1290457342,152846.09826261594,3315.19579,1758.2012266072022,3428293.8516329154,1802445.9204920272,890.73153,460.0690623679876,918828.8232775276,469149.8629645152,1722.63031,854.7991450862012,1771351.335261987,866563.9729498687,0.38261,100000,0,585359,6113.463325987739,0,0.0,0,0.0,30761,320.7448641761272,0,0.0,33874,351.04283073452467,1285106,0,56350,0,0,0,0,0,50,0.5117546919550073,0,0.0,1,0.0104439733052042,0,0.0,0.06208,0.1622539923159353,0.3142719072164948,0.01951,0.3385705483672211,0.6614294516327788,24.604391161157384,4.448409647281917,0.3190923957481603,0.2330335241210139,0.2287408013082583,0.2191332788225674,11.032520440686351,5.574345040664883,21.02868179067441,12356.967538424473,55.64185003482304,13.611092729845994,17.495055769431378,12.089640737479543,12.446060798066132,0.5486508585445625,0.7868421052631579,0.6777706598334401,0.5764925373134329,0.099195710455764,0.7023633677991138,0.9191176470588236,0.8663239074550129,0.7491289198606271,0.0888888888888888,0.4898247597512719,0.7131147540983607,0.6151877133105802,0.513375796178344,0.1024734982332155,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024102974388057,0.0049671055966102,0.0070924144648727,0.0094081788163576,0.0116780598958333,0.0137284855891638,0.0160713011023525,0.0183489048858937,0.0203693478127492,0.022465697317223,0.0245285534101047,0.0265654843810971,0.0285358780823889,0.0304522002409812,0.0324789850961786,0.0347250204052113,0.0367889860773251,0.0390009127873205,0.0410950361686206,0.0430325947685865,0.0578268222913578,0.0720370021556685,0.0854388890636963,0.0988621545450721,0.1102043398494338,0.1258976447072012,0.1404605263157894,0.1544653123802223,0.1676427212687285,0.1804418502344445,0.1953700909600379,0.2046586675907476,0.2144481809178665,0.2238053029556919,0.2317745895773004,0.2415922825303542,0.2509211907367292,0.2597810309324752,0.2679477429826453,0.274753609901444,0.2813913405591736,0.2881472903580493,0.2939666086874208,0.2993356358229002,0.3045273988411219,0.3089320699385142,0.3139369074125034,0.3190658508973886,0.3228703619704254,0.3266069846475278,0.3256591362484499,0.3248643586989451,0.3235945233294321,0.3216995447647951,0.3204633204633205,0.3178358677508767,0.3165883971348607,0.3174283043927394,0.3179886322904398,0.3185593099515255,0.3200710811821923,0.3208503421483366,0.3212468859254297,0.3225531914893617,0.3249084425597532,0.3247133958017065,0.3253565316600114,0.3286752903408554,0.3318807984256396,0.3348049158811598,0.3377374823454371,0.3421907449810959,0.3436646554461733,0.3445100897721169,0.3472550316545403,0.3520152635344622,0.3539701855795558,0.3573002203084318,0.3545232273838631,0.3612467142320691,0.0,1.8177986652981688,59.812932657684605,181.20316777410488,264.5714965730502,fqhc8_implementation,35 -100000,95647,44620,423.6306418392631,6121,62.751576107980384,4830,49.902244712327615,1863,19.132853095235603,77.26811230720266,79.67858157071171,66.14032678499974,68.05053168941042,77.02403805389632,79.43509742975452,66.03379970829388,67.94713690757125,0.2440742533063371,243.48414095719303,0.1065270767058592,103.39478183917096,128.24108,95.39269454459247,134077.47237236923,99734.120824064,252.97354,179.65510751395684,264049.8813344904,187394.64647501416,266.61495,147.01815248030252,276348.86614321417,151704.08030140758,3205.1441,1697.6620073552815,3314650.684287013,1738561.4262394854,873.8193,449.0766173570932,902650.9561198992,458578.8066308647,1638.08026,807.590213409545,1683562.2235930031,817291.5552481532,0.38182,100000,0,582914,6094.430562380419,0,0.0,0,0.0,30064,313.7160600959779,0,0.0,33719,349.2634374313883,1287558,0,56535,0,0,0,0,0,57,0.5959413259171745,0,0.0,0,0.0,0,0.0,0.06121,0.1603111413755172,0.3043620323476556,0.01863,0.325,0.675,24.345055383002013,4.351136184053043,0.3238095238095238,0.2349896480331263,0.2149068322981366,0.2262939958592132,11.273779709853573,5.8739880393681325,20.081116223760645,12315.545236426316,54.97694173218976,13.592741930489314,17.752974776873774,12.209081781492475,11.42214324333419,0.5594202898550724,0.7823788546255507,0.6764705882352942,0.5827996340347666,0.1146435452793834,0.7292143401983219,0.938095238095238,0.8029556650246306,0.7391304347826086,0.1531100478468899,0.4961636828644501,0.6909090909090909,0.6321243523316062,0.5299877600979193,0.1049457177322074,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024621807017721,0.0046952165579904,0.0066903553299492,0.0089438165704528,0.0111424297619895,0.0134488028527763,0.0154847396768402,0.0176311354001736,0.0198915933728778,0.0220993343573988,0.0241421040756466,0.0264106752134118,0.0283078062478784,0.0303486072193835,0.0323729128397762,0.034410025228504,0.0362193466842099,0.0380266040851081,0.039929236692856,0.0421944887554346,0.0572584100575823,0.0717017108254497,0.0848541487283953,0.0978416508738681,0.1105937750749609,0.1258513128488661,0.1406587099996811,0.1552764569162206,0.16807028432621,0.1808054657370903,0.1959965919263165,0.2055677766820905,0.2146965900424882,0.2238176600731637,0.2319830740071406,0.2404505604261458,0.2495302223614156,0.2585370804763623,0.2660767498464548,0.2726343944072641,0.2804364715841228,0.2870102319475862,0.2927251595151687,0.2982371871847831,0.3030413669721421,0.3077388523233845,0.3122696155871511,0.3174989798000408,0.3219978194278594,0.3257057398853876,0.3251762417956405,0.3230113518807156,0.3213203051196368,0.3208837606096097,0.3194002320530747,0.3170174254509755,0.3151499769998255,0.3167504848305558,0.3177578076949361,0.319071907547439,0.3199542788614687,0.3211548743539476,0.3222937684837553,0.3235399578683161,0.3242774148446351,0.3229128452387191,0.3243822311098414,0.3284057240118515,0.3316254912970241,0.3357051995547782,0.3388335314014078,0.3411274823830877,0.344161600810537,0.3480437461491066,0.3479168643826516,0.3544409863538424,0.3589823146137139,0.3534552845528455,0.3564221434415053,0.354705661792276,0.0,2.315339627805188,57.50705251174412,181.9329864231276,261.9445224285988,fqhc8_implementation,36 -100000,95817,44600,420.8543369130739,6016,61.59658515712243,4768,49.124894329816215,1898,19.38069444879301,77.40037147260112,79.68485318246734,66.25357880581787,68.05840308032444,77.1611039672328,79.44925878604963,66.14902283163613,67.95854557721978,0.2392675053683177,235.59439641771007,0.1045559741817356,99.85750310465846,128.7077,95.73527063045714,134326.58087813226,99914.70264197078,253.7589,180.45915131246065,264362.06518676225,187862.33268883463,265.0495,146.65191007476574,273773.23439473164,150620.5946270312,3224.95902,1713.0748761350446,3326189.4548984,1748302.290966158,898.60175,463.3385469745437,926116.785121638,471851.6724323899,1668.69836,819.973586913708,1706563.125541397,822888.1462927456,0.38087,100000,0,585035,6105.75367627874,0,0.0,0,0.0,30184,314.3596647776491,0,0.0,33421,344.9909723744221,1289578,0,56629,0,0,0,0,0,70,0.7305592953233769,0,0.0,0,0.0,0,0.0,0.06016,0.1579541575865781,0.3154920212765957,0.01898,0.3429614346929059,0.6570385653070941,24.24889373006293,4.4136120238330685,0.3166946308724832,0.2348993288590604,0.2260906040268456,0.2223154362416107,11.21762100774546,5.733289065605526,20.345860810588107,12274.444513635028,54.35139024351111,13.52479788507156,17.132428095702405,11.900823968486122,11.793340294251012,0.5635486577181208,0.7955357142857142,0.6973509933774834,0.5735849056603773,0.1252319109461966,0.7396449704142012,0.9205607476635514,0.8723897911832946,0.7644787644787645,0.1367521367521367,0.4938524590163934,0.7182080924855492,0.6274328081556997,0.5118601747815231,0.1220379146919431,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0021449023158874,0.0044957472660996,0.0067703160156487,0.0092117277061986,0.0115296316612827,0.0137691181256101,0.0158039978412064,0.0180904112662268,0.0203494011578635,0.0225130354769451,0.0248756218905472,0.0268430226596944,0.029242648266798,0.0314399432291506,0.0336636519087743,0.035461066102482,0.0375452383414331,0.039568568941937,0.0415247549426815,0.0435529370127098,0.0579743402524251,0.0724866452712238,0.0863337245368429,0.0996195960572497,0.1117585080602676,0.1262915460519365,0.1402831948448363,0.1541299424816866,0.1679664579177024,0.1812728947537542,0.1956271576524741,0.2045744427870376,0.21322179368787,0.2215994143420635,0.2297636063771302,0.2388637973786751,0.2468794270862382,0.2560077366828972,0.2633364728844909,0.270346739367003,0.2768924533324075,0.2835031645939843,0.289935506774747,0.2961706311145214,0.3013953375306901,0.3065982458953705,0.3111177899666892,0.3158323676603548,0.3196261197609448,0.3236789624522894,0.3232255196475961,0.3212894523131134,0.3196550363564624,0.3181785316616777,0.3170199177150326,0.3153353019477042,0.3137174362944122,0.3147459321284022,0.3153248527277384,0.3166607270135424,0.3178471313773126,0.3185524471382598,0.3194089289457137,0.3211479483333706,0.3233814075554378,0.3244977824158622,0.3247052793439262,0.3302660092333783,0.3341781063005983,0.3367696226715491,0.3405363424551144,0.3425526245670131,0.3447183321715987,0.3501719526175009,0.3525538519424325,0.3581345674617301,0.3610603290676417,0.3645957785742732,0.3637846655791191,0.3722409277964834,0.0,2.4705820537494394,59.08104931487965,173.7735738769543,256.73298247428863,fqhc8_implementation,37 -100000,95726,44724,422.5706704552577,6081,62.29237615694796,4794,49.58945323109709,1910,19.62894093558699,77.38943750387645,79.7569825179363,66.21815035492689,68.09360177998016,77.1458101419348,79.512051458647,66.11293897924098,67.98972987087585,0.2436273619416482,244.93105928929992,0.1052113756859114,103.87190910431345,128.4503,95.60396635301744,134185.1534588304,99872.28793955392,256.41591,182.75076379546132,267488.98940726655,190534.8220916588,269.66617,149.4155603260275,278908.206756785,153826.15655180608,3169.02073,1683.8026933889707,3283094.1750412635,1731563.727084564,868.09357,447.8501129240345,898382.1009965944,459400.14338636806,1670.0326,820.3784959078617,1718530.420157533,835772.9356072209,0.38092,100000,0,583865,6099.325157219564,0,0.0,0,0.0,30480,317.8864676263502,0,0.0,34072,352.18227022961366,1287294,0,56357,0,0,0,0,0,59,0.6163424774878299,0,0.0,0,0.0,0,0.0,0.06081,0.1596398193846477,0.3140930767965795,0.0191,0.331299859221023,0.668700140778977,24.64057079225844,4.177750013353621,0.3268669169795578,0.2405089695452649,0.2148518982060909,0.2177722152690863,11.095900143403876,5.962614503965054,20.49319720354455,12258.67194158283,54.55839530205907,14.07909917386022,17.56086135703656,11.621053795571818,11.297380975590473,0.5769712140175219,0.800520381613183,0.7083599234205488,0.5775862068965517,0.1262135922330097,0.7386109036594474,0.9130434782608696,0.8533653846153846,0.7520661157024794,0.1447963800904977,0.5143270622286541,0.7258297258297258,0.6559513466550826,0.5249376558603491,0.1211372064276885,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022992697033233,0.0045209881298719,0.0070522577371892,0.009425147267926,0.0118265573837173,0.0140933993197694,0.0162928221859706,0.0184179360476987,0.020570704127432,0.0223878305199258,0.0248803141049955,0.0269279730617608,0.0290857871360421,0.0310707407750692,0.0333515582285401,0.0354363664548132,0.0374416268883895,0.0395684199605768,0.0416956942177118,0.0438112106688893,0.0573591604448389,0.0716663177726606,0.0848682554334144,0.0980536482266222,0.1104058371379466,0.1260256301810184,0.1411931938727882,0.1550503921756436,0.1680889468006707,0.1805073116342896,0.1953362185905303,0.204528734637355,0.2133481234978739,0.2222671710655791,0.2312083415825249,0.2399056457507364,0.2482847102136442,0.2571820656453173,0.2642234925820063,0.2709354528379678,0.2784083677554468,0.2837218546143235,0.2897993469310492,0.2960136114738974,0.3014354066985646,0.3055138276651808,0.3100964244175139,0.3143815684131603,0.317967820373532,0.3220517686752069,0.322329157481585,0.3215713206510542,0.3199026462767828,0.3187019320952917,0.318271527994183,0.3151836622387991,0.313417273574622,0.3145079417062387,0.3155239702097926,0.3159262423465755,0.3163621432970642,0.31689738692082,0.3183555806229241,0.3182416601584291,0.3192643810621339,0.3202903452402633,0.3208147495809778,0.3240330536965469,0.3291201460571589,0.3322253877809433,0.334298773589175,0.3357910259111017,0.3385630681110696,0.3427191062127274,0.344834052128258,0.3479494149627704,0.3506652393332314,0.3542708541708341,0.3556164383561644,0.3553875236294896,0.0,1.9190066832212895,58.88364684812981,181.300786794204,252.6036610654392,fqhc8_implementation,38 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-100000,95797,44443,419.6164806831112,5964,60.96224307650553,4709,48.50882595488377,1880,19.20728206520037,77.30729635233612,79.63713137930586,66.1841846971827,68.03369430426504,77.07087765696942,79.40305242269203,66.07992383950504,67.93329543795676,0.2364186953667086,234.0789566138284,0.1042608576776586,100.3988663082822,127.0456,94.5676864435121,132619.60186644676,98716.75150945448,254.64053,181.28738379834664,265308.2873158868,188736.8433232216,268.25825,147.97773278344175,276898.0761401714,151936.31760339747,3166.97936,1690.228617239237,3266474.075388582,1725296.4222638586,898.12455,465.445704280039,926104.87802332,474467.8280977716,1658.0222,820.3894560030616,1696271.6473375992,826148.2584917356,0.37955,100000,0,577480,6028.163721202125,0,0.0,0,0.0,30232,314.89503846675785,0,0.0,33938,350.0527156382768,1292005,0,56774,0,0,0,0,0,59,0.6158856749167511,0,0.0,0,0.0,0,0.0,0.05964,0.1571334475036227,0.3152246814218645,0.0188,0.3343943975807735,0.6656056024192265,24.45188910670629,4.312021719387812,0.3172648120620089,0.2369929921427054,0.2274368231046931,0.2183053726905924,11.239740670351816,5.94095735452417,20.142422207275,12227.435639051777,53.86401716050009,13.56652272468127,16.9473683821755,11.435425286085527,11.91470076755779,0.5689105967296666,0.7840501792114696,0.7081659973226239,0.585603112840467,0.134453781512605,0.709214501510574,0.9073634204275536,0.8589743589743589,0.7003891050583657,0.1640625,0.5140324963072378,0.7093525179856115,0.654891304347826,0.5473411154345007,0.1251533742331288,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0026034016430807,0.0048471819417121,0.0070742748107098,0.0093678242669321,0.0115666327568667,0.0139942759948259,0.0163367699697127,0.0185795808364894,0.0206188728622103,0.0228713003061109,0.0249651410761154,0.0270925087519377,0.0292300258063189,0.0314282772114097,0.0333522463506473,0.0352829350442715,0.0372405941106453,0.0393797967226716,0.0415341771099611,0.0434026512272078,0.0581864847100065,0.0721925413238261,0.0853762065965853,0.0982574515491655,0.1101145621449574,0.1261176520323828,0.1399951239678181,0.1537668027905394,0.1667360555110755,0.1795459904396475,0.1938789790404013,0.2031106352142077,0.2116685150151129,0.2211664625612316,0.2302333259960378,0.2393026941362916,0.2487132250320995,0.2570508562357153,0.264485630845104,0.2709291786652593,0.2776521608051854,0.2835091420534458,0.2901439514312139,0.2952119035895711,0.3007218590609746,0.3056303579810757,0.310358235913903,0.3149126164051537,0.3180732587419849,0.3220657525543967,0.3201625313858365,0.3182570325427468,0.3172406984288172,0.3175078910028089,0.3167016259799765,0.3151384162604617,0.3125327157654299,0.3137161373094067,0.3149124910093502,0.3149788010518972,0.314914535527328,0.3161411485618266,0.315873281930942,0.3171255395763906,0.3178281542673262,0.3184031665842035,0.3197024962954519,0.3231391738025783,0.3261700262927257,0.3291400452398905,0.3317940746159473,0.3352934887201967,0.3362331724663449,0.3383452849101704,0.3408573596358118,0.3432639387413256,0.3420560747663551,0.3509465363012273,0.3591628959276018,0.3620414673046252,0.0,2.5035142055465527,57.87721366831966,175.39972925316854,252.686607607264,fqhc8_implementation,47 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-100000,95793,44262,419.2059962627749,5997,61.28840311922583,4712,48.51085152359776,1945,19.88663054711722,77.35663513503822,79.67713692447224,66.21681440737055,68.05531488750712,77.11659667369635,79.4382756667834,66.11256241466245,67.95410882577157,0.240038461341868,238.86125768883915,0.1042519927081002,101.20606173555302,129.17828,96.12268238010569,134851.25217917803,100343.93158174989,256.1444,181.67105015383217,266863.9670957168,189125.52727030416,261.03942,144.42005803503343,269235.35122608126,148023.22864786937,3209.92088,1703.4888539414803,3311588.1953796204,1739487.0356079102,885.98933,461.4597152135925,912401.960477279,469308.4777374687,1717.48928,840.7343862221288,1758497.531134843,848930.5062698656,0.37958,100000,0,587174,6129.602371780818,0,0.0,0,0.0,30510,317.77896088440696,0,0.0,33003,340.0770411199148,1286118,0,56462,0,0,0,0,0,61,0.6367897445533598,0,0.0,0,0.0,0,0.0,0.05997,0.1579904104536593,0.3243288310822078,0.01945,0.3390986988257696,0.6609013011742304,24.366982762615223,4.5409830095819865,0.3155772495755518,0.2236842105263158,0.2357809847198641,0.2249575551782682,11.519856528298574,5.850609001617841,20.927761247315185,12197.51687217827,53.76901840351188,12.710063964439284,17.002596943200615,11.81287187606516,12.243485619806815,0.5477504244482173,0.7950664136622391,0.6698049764626766,0.5707547169811321,0.1278127812781278,0.7138664710198093,0.9280397022332506,0.8231292517006803,0.7014388489208633,0.1701244813278008,0.4801433263660794,0.7127496159754224,0.6051625239005736,0.5242966751918159,0.1160919540229885,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024902062012208,0.0046002634512108,0.0067655292733395,0.009014770823816,0.0111810207255466,0.0133517870227143,0.0153653342571553,0.0175680225262449,0.0195627745428542,0.0216205707503248,0.023683131789301,0.0257065451634751,0.0277346601013579,0.0300830836705068,0.032005858629617,0.0339261540369333,0.0360263364942647,0.038102151931553,0.0401442032975595,0.0419586244234593,0.0564441244900727,0.0701895630535021,0.0835001939426978,0.0958145497724956,0.108385125882229,0.1240889790227517,0.139548190217852,0.1535018710665079,0.1662204111240306,0.178187700185322,0.193245758426664,0.2025252143081064,0.211404290464909,0.221204803479135,0.2291494859530485,0.2379549758047549,0.247060923104379,0.2554921877636419,0.263137597404807,0.2700942175819395,0.277916522141288,0.2840438717522976,0.2898000236658383,0.2951067221150273,0.3003037298019682,0.3051399390657571,0.3097401702116992,0.3145915636549,0.3179133730514129,0.322376337119359,0.3218446601941747,0.3204550776138727,0.3194638447971781,0.3182541980312681,0.3178820762440643,0.3153909818226404,0.3137217567910637,0.3148386034255599,0.3159499220743633,0.3164802065404475,0.3175947889604277,0.3178311484838268,0.3189490278507619,0.3203944560504975,0.3232182024150979,0.3242047170302494,0.3255516014234875,0.3277202884916901,0.3323864632649482,0.3352420819840455,0.3403115208210344,0.3431216931216931,0.3447993447993448,0.3483900503586143,0.3465829192837724,0.346217299080839,0.348889895786135,0.3527301713830211,0.3555190358805806,0.3535932721712538,0.0,2.6031456786966314,59.54364272787078,166.70793422856215,255.6661432887161,fqhc6_implementation,86 -100000,95661,44947,425.931152716363,6056,62.29288842893133,4760,49.27818024064143,1866,19.161413742277414,77.33925701013783,79.74618190686691,66.17727955560699,68.0837551382852,77.10612877425628,79.51517744460403,66.07702608621706,67.98746320752454,0.2331282358815514,231.00446226287372,0.1002534693899264,96.2919307606569,128.68746,95.77427055431176,134524.47705961677,100118.40829001552,257.6755,183.4547997188434,269003.1987957475,191415.9895033957,271.39299,149.49452191022317,282134.4539572031,154928.68240390584,3192.16062,1683.4860043481692,3301246.7672301144,1724141.5564840098,896.53549,454.7184875843512,928695.7798894012,466838.8032577026,1643.35114,796.5394781034486,1687252.548060338,804000.6014253914,0.38268,100000,0,584943,6114.748957255308,0,0.0,0,0.0,30615,319.5346065794838,0,0.0,34247,355.850346536206,1283887,0,56189,0,0,0,0,0,67,0.7003899185666049,0,0.0,1,0.0104535808741284,0,0.0,0.06056,0.1582523257029371,0.3081241743725231,0.01866,0.3326498422712933,0.6673501577287066,24.541684187561685,4.341703820735695,0.323109243697479,0.2350840336134453,0.2275210084033613,0.2142857142857142,11.156831152930575,5.690364794200101,19.797747949237312,12296.220063920477,54.33527992717474,13.56722807993648,17.40007664961568,11.487803121369154,11.880172076253436,0.5649159663865546,0.7980339588918678,0.6950585175552666,0.5745098039215686,0.1301939058171745,0.73061863743148,0.9209302325581395,0.8650793650793651,0.7344398340248963,0.1447368421052631,0.5041630778064886,0.7213352685050798,0.6396551724137931,0.5250320924261874,0.1263157894736842,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023502953065007,0.0046333377267243,0.0067994073352412,0.008737795027585,0.0108348424115408,0.0128628169874732,0.0148069588627602,0.0168020905638806,0.0191863436573648,0.0215895829494502,0.0241661796520152,0.0265046878690477,0.0287186661043623,0.0308675046363074,0.0331024659117886,0.0350586896943999,0.0372918587903718,0.0392944645155932,0.0412461240713378,0.0431318566720894,0.0588038582520822,0.0724161045707821,0.0856458878004221,0.098559818082284,0.111024311970188,0.1266677961794231,0.1414840854299642,0.1555787700802677,0.1688000598847219,0.1816600450982497,0.1964688244874187,0.2051762818775943,0.2139138201463924,0.2233138375939191,0.2308658433130983,0.2398446601941747,0.2496450888116343,0.2582989655871814,0.2644927536231884,0.2714601491186879,0.2781782627309859,0.2849805192525945,0.2911699596320717,0.2975298728381892,0.3029022465088039,0.3084119060824551,0.3132362872364373,0.3176469093127287,0.3217833307465466,0.3254275700318866,0.325106199924719,0.3237054527483389,0.3218775487245831,0.3200986116517452,0.3181145040428871,0.3156127417311537,0.3141355472079295,0.3146513680494263,0.3152726963328512,0.3159054558379243,0.3171027357663689,0.3186023622047244,0.3200559487275839,0.3209950914770192,0.3221481339345677,0.3239356178608515,0.3240223463687151,0.3272613262266813,0.3297890944702878,0.331544851158539,0.3340645279224933,0.3361398616399421,0.3381331634278433,0.3385500575373993,0.3376427290742663,0.3448071918618405,0.3456525072841588,0.3505341664986898,0.3467719967311359,0.3462406015037594,0.0,1.9125822135639887,56.42876632387604,188.2649707872074,250.583403608306,fqhc6_implementation,87 -100000,95658,44602,422.5678981371135,5990,61.41671370925589,4724,48.83020761462711,1899,19.527901482364257,77.25972704763646,79.66185160391558,66.13826401927561,68.04160836340844,77.02040534322501,79.4232694170126,66.03436169567043,67.94091970408888,0.2393217044114521,238.5821869029741,0.1039023236051832,100.68865931955884,128.66348,95.7271935152051,134503.6275063246,100072.33426917256,255.11033,181.82801757974556,266281.210144473,189672.54968716213,268.50237,148.47213240090872,278210.3117355579,153107.35677013657,3144.47325,1667.4179798849682,3253439.8691170625,1709339.7728208513,843.46467,436.355047060499,873024.8071253842,447436.1235448145,1664.14642,806.4877067290205,1712693.1568713542,817617.0635662497,0.38031,100000,0,584834,6113.801250287483,0,0.0,0,0.0,30340,316.6070793869828,0,0.0,33938,351.4395032302578,1280472,0,56237,0,0,0,0,0,65,0.6795040665704907,0,0.0,1,0.010453908716469,0,0.0,0.0599,0.1575030895848123,0.3170283806343906,0.01899,0.3310520452013369,0.6689479547986631,24.402207656242545,4.348424108320185,0.3283234546994072,0.2345469940728196,0.2146486028789161,0.2224809483488569,11.137888455927012,5.689849879044972,20.20494388868989,12295.384380083657,53.94465487999562,13.56144048787338,17.635078035692533,11.665851313240628,11.082285043189067,0.5662574089754445,0.796028880866426,0.7014829142488717,0.5537583254043768,0.1213017751479289,0.7332843497428362,0.9346846846846848,0.8692660550458715,0.6809338521400778,0.1294642857142857,0.4986619090098126,0.7033132530120482,0.6358744394618834,0.5125944584382871,0.1189873417721519,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023606650388547,0.0045634317006388,0.0065969085871451,0.0086983030179859,0.0112000651048289,0.0134654756205628,0.015838211597691,0.0180236298467225,0.0201067724846079,0.0223603884131601,0.0246289248822919,0.0268912742026603,0.0289491281312689,0.0310001648396934,0.0330071835521426,0.0350196966407146,0.0369848684142388,0.0389618479107189,0.0410398851507396,0.0428169307756463,0.0576396580910781,0.071768230094057,0.085485699886607,0.0987599738941872,0.1110606812256573,0.1267890413279132,0.1416448947513753,0.155257661651251,0.1678630649906392,0.1805439195720822,0.1959896018725258,0.2048764629388816,0.2140981927907711,0.2227493344143394,0.2304037742920446,0.2397242787847842,0.2481356841787507,0.2568817676818893,0.2638617239026609,0.2710386526083914,0.27777069251371,0.2840308150510652,0.290505908594751,0.2972550903958195,0.3020175086142869,0.3070727036876892,0.3112078482537134,0.3166609263582207,0.3205021573010345,0.3252229687644946,0.3237908673331532,0.3231181237144711,0.322103835175084,0.3208310377823528,0.3194036526276556,0.3175742117878434,0.3156898909275925,0.3159870891245636,0.3162182515232423,0.3165458612975391,0.3188773115554304,0.3197620228061477,0.3201982860023525,0.3216599780283837,0.3224827851880387,0.3236191917347178,0.3255066029143898,0.3300251256281407,0.3330762759394279,0.3366116751269035,0.3380948048403239,0.3415679221328819,0.3437952984181004,0.347027771402341,0.3478178547761053,0.3549117787315212,0.3604758961681087,0.366160081053698,0.3739495798319328,0.381139489194499,0.0,2.1544252632238536,59.955187257638585,171.59611990580188,251.5981608388109,fqhc6_implementation,88 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-100000,95726,43865,414.58955769592376,6182,63.38925683722291,4846,50.02820550320707,1938,19.89010300231912,77.41869514561299,79.7789375539144,66.23102992785275,68.09833487393625,77.17509680563882,79.5356957349835,66.12716483940635,67.99718037288007,0.2435983399741701,243.2418189308976,0.1038650884463976,101.15450105618606,122.628,91.23222876558016,128103.1276769112,95305.58966799005,247.87323,175.49924172304773,258477.1430959196,182871.781671696,259.6834,142.963801245735,268293.0969642521,146899.11422011227,3294.39989,1730.6842869717675,3408482.617052838,1774949.822380303,905.62435,463.6032351071804,934212.1053841172,472455.5137655189,1708.97748,826.3501762673641,1756630.0378162672,838800.6371933585,0.37714,100000,0,557400,5822.869439859599,0,0.0,0,0.0,29434,306.8340889622464,0,0.0,32838,338.9988091009757,1328055,0,58131,0,0,0,0,0,59,0.6163424774878299,0,0.0,1,0.0104464826692852,0,0.0,0.06182,0.1639179084690035,0.3134907796829505,0.01938,0.3312826822516149,0.6687173177483852,24.684844258015563,4.487249816345342,0.3330581923235658,0.2234832851836566,0.2298803136607511,0.2135782088320264,11.415273178889889,5.718865846075321,20.535102802372013,12231.260896159123,55.00812136015982,13.042282849630093,18.330055263333577,11.463066700298508,12.17271654689764,0.5610813041683863,0.7876269621421976,0.70817843866171,0.5603864734299517,0.1283662477558348,0.7146153846153847,0.9115479115479116,0.8628841607565012,0.6978723404255319,0.1234042553191489,0.5047941342357586,0.7130177514792899,0.653232577665827,0.52,0.1296928327645051,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022381106700153,0.00457181088314,0.0068493150684931,0.0089904305247973,0.0114090479241023,0.0135140639957634,0.0157225009176556,0.0178957899465065,0.0201030190299041,0.0226500450339801,0.0247122372210776,0.0267639902676399,0.0287834865026007,0.0309208290859667,0.0327375119903458,0.0347970773348766,0.0367194780987884,0.0386079955176957,0.0407573378804104,0.0428504453820909,0.0574680240146175,0.0713725244028749,0.0843736231458364,0.0966079410991322,0.1085704642774273,0.1251891274216245,0.1397214910418612,0.1538707306942713,0.1666524164760703,0.1792767568843261,0.1945632616120586,0.2032685751393473,0.2126729313495171,0.2210815184116155,0.2295585032666798,0.2392206785852659,0.2479761825115407,0.2560808380541318,0.2630600820433787,0.2694200311269797,0.2765627710634361,0.2824196376388077,0.2886808731931591,0.2945244818838846,0.3002958579881656,0.3053252982412987,0.3107125908534605,0.3148094046515172,0.3191426135042249,0.3223614914682958,0.3219247165776839,0.3206919768608214,0.3198621950362089,0.3188274141685051,0.3190832900689757,0.3174826457906486,0.3168280795037346,0.3173679205063457,0.3167965618977778,0.3169640469866847,0.3172443479562808,0.3192570561934963,0.3205181693020151,0.3215821727019499,0.3227143165105751,0.3247581753585228,0.3251259410199807,0.3270267743041486,0.3304999479582278,0.3316392353102154,0.3345309201958054,0.3394562821454812,0.3422935722730384,0.3467838893898406,0.3478099480326652,0.3477395174513937,0.350722433460076,0.3504616619831393,0.3516304347826087,0.3587038432554634,0.0,2.380851037239504,57.0063176298257,184.168651213678,261.16010815326166,fqhc4_implementation,13 -100000,95670,44326,419.7031462318386,6046,62.06752377965925,4833,49.80662694679628,1919,19.5986202571339,77.2656064282761,79.64703825792958,66.14809085222389,68.03374916295144,77.01752114543665,79.40138862575536,66.04082034499494,67.93062424237907,0.2480852828394546,245.6496321742208,0.1072705072289466,103.12492057236966,123.10826,91.608670006559,128680.10870701369,95754.8552383809,247.88158,176.07461668032627,258551.71945228396,183494.7911365384,263.18765,145.2805419212102,271712.65809553675,149027.09918075378,3243.05937,1716.3419713103258,3345806.8673565383,1749990.625389699,887.20289,457.4360030572148,913273.0532037212,464055.0256686676,1694.89636,835.9680017733475,1733028.7132852513,838797.3897328066,0.38033,100000,0,559583,5849.095850318804,0,0.0,0,0.0,29413,306.6896623811017,0,0.0,33258,343.11696456569456,1316732,0,57781,0,0,0,0,0,69,0.7212292254625274,0,0.0,1,0.0104525974704714,0,0.0,0.06046,0.158967212683722,0.3173999338405557,0.01919,0.3331756543677073,0.6668243456322926,24.11451438234404,4.430916370966862,0.3153320918684047,0.2350506931512518,0.2288433685081729,0.2207738464721705,11.184831404884964,5.682646676002332,20.79559168713233,12226.880622350556,55.368354701193816,13.655305878251127,17.490776076146325,11.954772489347452,12.26750025744891,0.5545210014483758,0.7772887323943662,0.6837270341207349,0.5932521087160263,0.1103074141048824,0.7155490051584378,0.9408983451536644,0.8524590163934426,0.7023809523809523,0.1254901960784313,0.4916570771001151,0.6802244039270687,0.618049225159526,0.5595092024539877,0.1057579318448883,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023898976192163,0.0045918522498048,0.0068497320993667,0.0090832427379779,0.0111573315975224,0.0134408602150537,0.0158002038735983,0.0177410299596794,0.0198491383715938,0.0221571777998383,0.0240387079578886,0.026114270463364,0.0284063454203378,0.0304796424820314,0.0326084713940869,0.03467622777198,0.0366716017683539,0.0386343123320642,0.0408209948427882,0.0427633635511097,0.0577272632304703,0.0715385179212783,0.0844958066987855,0.0969809216134022,0.1087208811613774,0.1244311326545731,0.1384322969758749,0.1523205626898278,0.1654937862291715,0.1782388761800431,0.1925002697744685,0.2011081113315768,0.210998376181083,0.2209520260420662,0.2292688843070884,0.2382744418911868,0.2466370721561874,0.2549958860723826,0.2625620858574952,0.2698199593789803,0.2768783246607252,0.2835380144370488,0.2898681339531354,0.2961272891023717,0.3017836488707615,0.3067870285756625,0.311652810693551,0.3160600609794991,0.3195142541723488,0.3233978346613018,0.3230349226943453,0.3220252324954744,0.3218304682198598,0.3207738716788491,0.3198890247904298,0.3176385534755657,0.3152757908122715,0.3162547951069329,0.3167957239772493,0.3170146044261266,0.3177614105148153,0.31951544566666,0.3203918264166842,0.3206436244325588,0.3229773150049525,0.3243652700867203,0.3235403389442999,0.3259715639810426,0.3293552715203728,0.3339592489013184,0.3366617808721143,0.3401158157573182,0.3443324937027708,0.347148288973384,0.3501930865592917,0.3517044779665043,0.351787072243346,0.3519564340459863,0.3517615176151761,0.3592523364485981,0.0,2.7480967199830144,59.36662837967143,179.33303134311188,260.83529361616013,fqhc4_implementation,14 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-100000,95732,44092,416.5691722725943,6105,62.706305101742366,4783,49.39832031086784,1895,19.481469101240965,77.39336550786155,79.7613657531613,66.21979720769033,68.09560022345845,77.15417209487417,79.52057522060211,66.11735941297243,67.99459316784147,0.239193412987376,240.7905325591884,0.1024377947179004,101.0070556169751,123.44508,91.81180904723657,128948.60652655333,95905.0359829906,248.25106,176.11003981586563,258906.17557347592,183548.90717405427,260.36022,143.50967791967918,269045.7945096728,147501.62804323022,3211.24191,1689.5945443234566,3321092.539589688,1731605.8834281706,868.72616,442.66949637146143,895099.5278485772,450078.3081654657,1667.04717,808.1199033155889,1715415.5872644468,820960.8051230425,0.37795,100000,0,561114,5861.300296661513,0,0.0,0,0.0,29525,307.8281034554799,0,0.0,32886,339.6043120377721,1322463,0,57930,0,0,0,0,0,59,0.6163038482430118,0,0.0,2,0.0208916558726444,0,0.0,0.06105,0.161529302817833,0.3104013104013104,0.01895,0.3368551895587321,0.6631448104412678,24.69150869941428,4.391519196248187,0.3244825423374451,0.2301902571607777,0.2239180430692034,0.2214091574325737,11.203401153687045,5.749232997255456,20.104453317198764,12279.8156316017,54.19784665120488,13.291254698007496,17.501154400750657,11.72799428756514,11.67744326488157,0.5609450135897972,0.7856494096276113,0.6926546391752577,0.5873465533522191,0.1129785247432306,0.7331768388106417,0.927860696517413,0.8839506172839506,0.6951219512195121,0.1555555555555555,0.4981455064194008,0.703862660944206,0.6251089799476897,0.5547355473554736,0.1016548463356974,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0021170559753651,0.0045925039791563,0.0069107588642406,0.0089297505968405,0.0110252237591537,0.0134089474434421,0.0156393369084273,0.0177324513046674,0.0197687849454671,0.0219749851589527,0.0241767702130712,0.0261739799846035,0.0283003351220214,0.0302471868469006,0.0324240705409168,0.0346028269135394,0.0364154069165458,0.0387157695939565,0.0409073425301217,0.0431829310219092,0.057674438029213,0.0719667636409301,0.0849592984222893,0.0974260258554493,0.1091353962327828,0.1240519183777093,0.1391282203641611,0.1529409261150834,0.1665723287232338,0.1791507198833606,0.1939438954552304,0.2036185882531065,0.21298258195608,0.2220619570562202,0.2307734600074772,0.2395187710288648,0.2476270146673359,0.2563072943029076,0.2642907391018222,0.2720765089909517,0.2789306866555617,0.2854636063732715,0.2916114215361303,0.2978068072866731,0.3022084087073706,0.306117424009258,0.3115632494004796,0.3161862696569318,0.3203409531189461,0.3253829465518374,0.3246704432571751,0.3226470225112144,0.3213257091476179,0.320942295223687,0.319812676912133,0.3183684684547161,0.3165415431203078,0.3173256156185617,0.3188242907257927,0.3197245012368969,0.3209447465291403,0.3219417016496186,0.3230360578934159,0.3241987716359575,0.3247158886139208,0.3263042799125273,0.3270618996191667,0.3299978110635104,0.3330307262569832,0.3347715936980445,0.3403079710144927,0.3425273968976653,0.3458509230672295,0.3479597325751172,0.3505242278265797,0.3513513513513513,0.3542682926829268,0.3502415458937198,0.3528617710583153,0.356852604359069,0.0,2.147780287352836,56.1163089878983,178.91552399304774,262.0666313151764,fqhc4_implementation,16 -100000,95604,44136,417.6812685661688,6071,62.5078448600477,4723,48.92054725743693,1878,19.35065478431865,77.18003533564423,79.62217543516668,66.080476422041,68.01842017379862,76.94875554852675,79.38960309946019,65.98236007060387,67.92163408958699,0.2312797871174865,232.57233570649305,0.0981163514371274,96.78608421162949,122.7171,91.36506632978158,128359.79666122756,95566.1544807556,247.97371,175.77377237222757,259014.6437387557,183494.85625311447,259.68148,143.05042431862506,269180.03430818795,147596.38267183967,3160.76577,1668.7134581219836,3277052.978954856,1716525.3578634174,879.24355,451.58756496126233,909875.4131626292,462598.4473749431,1644.39734,792.2349206647207,1696025.9194175976,808064.1212464151,0.37982,100000,0,557805,5834.53621187398,0,0.0,0,0.0,29398,306.9850633864692,0,0.0,32874,340.52968495042046,1317062,0,57831,0,0,0,0,0,67,0.7008074975942429,0,0.0,0,0.0,0,0.0,0.06071,0.1598388710441788,0.3093394827870203,0.01878,0.3345841150719199,0.66541588492808,24.44323908608119,4.348972353059946,0.3139953419436798,0.2422189286470463,0.2161761592208342,0.2276095701884395,11.633355336601213,6.2063794441953295,20.077453157974546,12314.404805337286,54.0293634536872,13.832437123519052,16.772051937714284,12.224075402647944,11.200798989805932,0.5782341731950031,0.791958041958042,0.6999325691166555,0.6074418604651163,0.1312438785504407,0.756079027355623,0.9292237442922374,0.8619791666666666,0.7491289198606271,0.2028985507246377,0.5095391840328735,0.7067988668555241,0.643312101910828,0.5558375634517766,0.113022113022113,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0021892483580637,0.0043416074091356,0.0070371047340522,0.0092524808849845,0.0112806833569196,0.013516544005219,0.0157604091173558,0.0179671930093515,0.0200145299757492,0.0221359103905553,0.0244327918646294,0.0266183133173753,0.0288554551629036,0.0307712924973712,0.0329370694374154,0.0348509933774834,0.0371694808088974,0.0393107889161231,0.0412065322605826,0.0431018296372019,0.0571383762873124,0.0714555210866102,0.0848700732381342,0.0978816192813727,0.1102941953203401,0.1259575550163698,0.1405851335261098,0.1544904557143009,0.1678929837526374,0.1806678420916831,0.1956998304553946,0.204988824512293,0.2146107261716405,0.2239994734070563,0.2324623858882229,0.2409810003446397,0.2494876762337764,0.2586220521330759,0.2661405127153871,0.2726572292689658,0.2795988798382505,0.2859155921933347,0.2922649044404298,0.2984359961501444,0.3032366520081373,0.3084538375973303,0.3126113690550884,0.3178746302152402,0.3215323920265781,0.3250991801110817,0.324445164863368,0.3224364193356976,0.3217880570006786,0.3204702126115666,0.3204274754470282,0.3185468980797636,0.3163869693978282,0.3169499917478132,0.3170920207467454,0.3174822415153907,0.3193871204839713,0.3195735048844412,0.3193894736842105,0.3205581186002025,0.3220408656752508,0.3226448705857697,0.3240415129942534,0.326310153691106,0.329011174362218,0.3322571644943999,0.3345068812582872,0.3376720367011629,0.3401442307692308,0.3453418999541074,0.346040777619725,0.3493788819875776,0.355397463656047,0.3551575046324892,0.3524315259921744,0.3530805687203791,0.0,1.907841711009648,58.42522985869765,173.68565433184267,257.87302640587365,fqhc4_implementation,17 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-100000,95793,44468,420.3647448143393,6179,63.29272493814788,4890,50.50473416637959,1977,20.283319240445543,77.31829074272538,79.65173115371614,66.18746572751799,68.03910524359115,77.0780882769182,79.41135194524786,66.08348471049082,67.9370985335351,0.2402024658071866,240.37920846828345,0.1039810170271664,102.00671005604534,123.26402,91.68726063273164,128677.48165314792,95713.94635592542,247.53687,175.31417209605218,257998.83081227227,182604.28433815847,265.71281,146.63861098468283,274142.3172883196,150511.8194795837,3291.85633,1730.844714848049,3401230.507448352,1771662.9866984535,917.33247,479.0978170962012,945504.0660591066,488036.4230096872,1736.30889,842.8023803748073,1782278.7886380006,853824.0763248889,0.38243,100000,0,560291,5848.976438779451,0,0.0,0,0.0,29410,306.4420155961291,0,0.0,33518,345.88122305387657,1320013,0,57918,0,0,0,0,0,59,0.5845938638522648,0,0.0,1,0.010439176140219,0,0.0,0.06179,0.1615720524017467,0.3199546852241463,0.01977,0.3272223078108149,0.672777692189185,24.38189435851658,4.449820549606634,0.3198364008179959,0.2353783231083844,0.223721881390593,0.2210633946830265,11.483535526081354,5.959338707096762,21.02294651040145,12444.11589110607,55.471663617459015,13.912187291380205,17.675403413252265,11.927660658133586,11.956412254692946,0.5693251533742332,0.787141615986099,0.7078005115089514,0.5883441258094357,0.1234003656307129,0.7473684210526316,0.9327146171693736,0.8823529411764706,0.7238493723849372,0.1872340425531914,0.5028089887640449,0.7,0.6426690079016681,0.5498812351543944,0.1059371362048894,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022582735852878,0.0047034495342165,0.0067985104159267,0.0090099241216085,0.011379699592202,0.0136625095444133,0.0160050563744979,0.0181406127178251,0.0203599791494189,0.0224130343564184,0.0245854598372584,0.0268672646292153,0.0287071012303043,0.0306450284207924,0.0326872891932871,0.0350931580742164,0.037012106086182,0.0392020581339861,0.0412816861885113,0.0431513838848741,0.0583484630313654,0.0723071773738049,0.0862900520046971,0.0993577277648716,0.1118502899314707,0.1276111904384155,0.1423722701286579,0.1567249968067441,0.1701452681051057,0.1827707884209058,0.1977069953881298,0.2070824627310028,0.2162235692287601,0.2253433276795973,0.2336485638479407,0.2429861996342071,0.2514519299499642,0.2598243441053935,0.2674501788451712,0.2741835682365074,0.2820717500202455,0.2896813797135341,0.2961998650839674,0.3015564901685898,0.307442697066187,0.3126333049771301,0.3175752715791056,0.3219861590813504,0.3248816548861941,0.3282784880415669,0.3269383738017877,0.3259242927420799,0.324150868878357,0.3243118204950266,0.3234865604186489,0.3213782542113323,0.3196725205466436,0.3210840304369977,0.32234714307716,0.3225881385915694,0.3238275467950759,0.3254034336465644,0.3257803468208092,0.3267193391991381,0.3267928166807279,0.3273745648703117,0.3290517782725352,0.3312574699628861,0.3325931408832963,0.336466464871754,0.3406929968915707,0.3441974780936097,0.3449850916703673,0.3443891229414018,0.3459720121028744,0.3457663708323339,0.3453304374806081,0.3486031224322103,0.3561719833564494,0.3592009220130618,0.0,2.0610793551081223,58.47832230783255,178.6546314045414,270.5226449187624,fqhc4_implementation,22 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-100000,95726,44486,420.3455696467,6332,64.79953199757642,4970,51.21910452750559,2032,20.78850051187765,77.39494292267749,79.7628140417381,66.22606035295941,68.10349225205336,77.13999742245345,79.51153083112108,66.11527476275536,67.9980071878762,0.2549455002240393,251.283210617018,0.1107855902040455,105.48506417715942,122.62338,91.20929360881902,128098.30140191798,95281.6304962278,248.5856,176.16087680752517,259169.40016296515,183511.0385971681,263.90998,145.7917774757896,272477.93702860246,149679.7842252278,3353.09747,1775.1553697756497,3457288.0826525707,1808893.602339648,908.09828,468.7558091409329,933820.0071036082,474861.6563325884,1782.99974,869.7355746999447,1825248.271107118,874379.3466659568,0.3828,100000,0,557379,5822.650063723544,0,0.0,0,0.0,29529,307.7638259198128,0,0.0,33356,344.0757996782484,1326893,0,58118,0,0,0,0,0,69,0.7208073041806824,0,0.0,0,0.0,0,0.0,0.06332,0.1654127481713688,0.3209096651926721,0.02032,0.3281203007518797,0.6718796992481203,24.560351472614496,4.39575020018034,0.3394366197183098,0.2183098591549295,0.2197183098591549,0.2225352112676056,11.227007398808595,5.9288026461483465,21.60760397184541,12437.615529931663,56.6619942698875,13.043306438411548,19.237745355742167,12.333197207332155,12.047745268401632,0.5633802816901409,0.784331797235023,0.7172495554238293,0.5524412296564195,0.1172161172161172,0.7326086956521739,0.9365853658536586,0.8568376068376068,0.7038461538461539,0.1776859504132231,0.4983286908077994,0.6918518518518518,0.6636587366694011,0.5059101654846335,0.1,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024517253257147,0.0044613887086307,0.0068090719975645,0.0087987563882425,0.0111095285571855,0.0134569347527122,0.0158184599694033,0.0179083752794993,0.0203311867525298,0.0223295605722589,0.0244222393031001,0.0267101913443376,0.0289212863957887,0.0312049433573635,0.0334124200536414,0.0356109457671957,0.0375926616142792,0.0397260984593038,0.0414279922238047,0.0434089630601912,0.0579784290591686,0.0719166256840607,0.0853879794028504,0.0985142424529194,0.1103694799443249,0.1261286025416023,0.1410512026470962,0.1553713203209808,0.169041616817638,0.1814750477170859,0.1960421197700209,0.2048836404533264,0.2142531084253543,0.2231159293582794,0.2319444291790774,0.2409442544573193,0.2507745113334967,0.2596249985957107,0.2669899612499716,0.274161825915931,0.2813528019853408,0.2885948330182735,0.295298368243323,0.3009429114332493,0.3061985923853133,0.3109250928042874,0.3160417993183265,0.3212926309378806,0.3253849333471117,0.3295459033876213,0.329290756302521,0.328660371912753,0.328175116763266,0.3271378683367485,0.3264170265817712,0.3247693225811388,0.3227264823508955,0.3234128284085697,0.3229611724854035,0.3227511344425661,0.3236940123907387,0.3257256901219199,0.3268094379950547,0.3277487378814279,0.3292128616435391,0.3312766346832597,0.332153055396916,0.33607742097656,0.3393308968231656,0.3413947587519327,0.3441120131350907,0.3441454854833564,0.3467289130023342,0.3504063793896642,0.3486593655589123,0.3525557011795543,0.3509779571561627,0.3517536704730832,0.3524363233665559,0.3537051184110008,0.0,2.740503029824974,60.08602161112216,187.1274000894443,265.1721422066656,fqhc4_implementation,24 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-100000,95811,44398,420.55713853315376,6127,62.9259688344762,4759,49.221905626702565,1885,19.39234534656772,77.3913679853635,79.70875764844442,66.24344531057635,68.07870968206545,77.15923054315255,79.47407729275663,66.14428156717976,67.98010865526116,0.2321374422109556,234.6803556877859,0.0991637433965877,98.60102680428896,123.64836,91.96476106178956,129054.45095030844,95985.59775160423,247.90821,175.65566242438211,258425.60875056105,183014.0718961102,263.31128,144.81193470835217,272257.65308785,149043.7924448558,3187.29006,1679.205552760498,3299081.9634488733,1725061.7494447394,871.60436,446.3981187674437,902114.350126812,458317.4570429743,1657.86764,801.3396414705073,1706966.830530941,817953.3830342318,0.38056,100000,0,562038,5866.1114068322,0,0.0,0,0.0,29422,306.6349375332686,0,0.0,33249,343.57224118316265,1322584,0,58092,0,0,0,0,0,62,0.6471073258811618,0,0.0,1,0.0104372149335671,0,0.0,0.06127,0.1609995795669539,0.3076546433817529,0.01885,0.3457769482034531,0.6542230517965469,24.682276215422917,4.278462632903266,0.3198150872031939,0.2372347131750367,0.2214750998108846,0.2214750998108846,11.211360788732373,5.817567689594648,20.01688283757244,12338.831480715851,54.13973875601226,13.660737536589243,17.189545472311572,11.781930811961374,11.507524935150064,0.5681865938222316,0.7971656333038086,0.6990801576872536,0.5825426944971537,0.1195445920303605,0.7425287356321839,0.9288990825688074,0.854320987654321,0.725,0.1964285714285714,0.5023161551823973,0.7142857142857143,0.6427931960608774,0.5405405405405406,0.0987951807228915,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0020955234759369,0.0042259087730676,0.0062796737410217,0.008296943231441,0.0104306453580578,0.0128147710848278,0.0148184384586378,0.0168877551020408,0.0192488454779516,0.0213508204771453,0.0236470564127784,0.0256431305347193,0.0279916528747211,0.0301039843508699,0.0319919143582021,0.0341581856692669,0.0360103921913653,0.0380611715914981,0.0401138689468161,0.0420840014159881,0.0573518211315951,0.0712366294085048,0.0843805351472021,0.0972086524420351,0.1098244578846437,0.1255361859482303,0.140983919352958,0.1549261319520522,0.1688846675133133,0.1807071475241267,0.1951906738648829,0.204315132133365,0.2132752874249546,0.2231721698113207,0.2325198070393283,0.2416773650892027,0.250381849601427,0.2586094574862406,0.2657067766273195,0.2730360205831904,0.2805564220766466,0.2871539171152656,0.2932321061704489,0.2993211101283675,0.3039355949465312,0.3092584391300069,0.3144566126796618,0.3200893934199332,0.3233925987182137,0.3274993091287126,0.3269814411946392,0.3263131881710096,0.3245193321987651,0.3226462443752163,0.3212527433418352,0.3197642375995101,0.3183638579773004,0.3191639459911735,0.3198395082806898,0.3198907455012853,0.3217057169634489,0.3232077523979036,0.3237316561844863,0.3244729605866178,0.3250528541226216,0.3274538879783553,0.3285080484614072,0.3316674524595316,0.3351468988030467,0.3364682539682539,0.3397987191216834,0.3419968982298518,0.3427858148764562,0.3453880852387618,0.3477637614678899,0.3544871018529732,0.3588308457711442,0.3594717292612464,0.3678226264923251,0.3682140047206924,0.0,1.75764546195618,57.77237570503479,175.9207090761507,259.9335675522777,fqhc4_implementation,28 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-100000,95701,44412,420.1210018704089,6155,62.91470308565219,4846,49.93678226977775,1931,19.68631466755833,77.3208766303194,79.68200796709941,66.18772816386509,68.05620503414787,77.07911526573582,79.4448211068071,66.080639274309,67.95455470575276,0.2417613645835814,237.1868602923115,0.1070888895560955,101.65032839510955,123.10386,91.57449952755672,128633.82827765644,95688.13233671198,247.89041,175.48691220132173,258503.36987074325,182849.30481953133,257.74021,142.75402078299058,266476.8288732615,146716.5026785076,3263.53412,1737.145532339161,3363268.973155976,1768506.0202498843,878.2621,451.4720014903842,901608.530736356,455646.5256270934,1702.30464,843.483419495704,1736654.5072674267,843302.9544273042,0.38217,100000,0,559563,5846.99219443893,0,0.0,0,0.0,29455,307.0605322828393,0,0.0,32555,336.39146926364407,1321653,0,57932,0,0,0,0,0,66,0.6791987544539765,0,0.0,0,0.0,0,0.0,0.06155,0.1610539812125493,0.3137286758732737,0.01931,0.3317851060535686,0.6682148939464313,24.602383096995176,4.360736972285811,0.3312009905076352,0.2195625257944696,0.2263722657862154,0.2228642179116797,11.1218754807736,5.740864679111723,20.75811554366163,12384.735096721057,55.08077948318073,12.812512504696128,18.08072584834835,11.98525676835393,12.202284361782317,0.5517952950887329,0.7922932330827067,0.6710280373831776,0.5888888888888889,0.1075660893345487,0.7021897810218978,0.8992805755395683,0.8637413394919169,0.7366255144032922,0.1227436823104693,0.4925201380897583,0.723338485316847,0.5998293515358362,0.5459976105137395,0.1024390243902439,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0025106042660025,0.0045900376930247,0.006867518766484,0.0090186161299168,0.0115012660544861,0.013409357022858,0.0155671774168884,0.0176287449599346,0.0197788044811513,0.0220884767344264,0.0241187384044526,0.0263690017962535,0.0286539726928771,0.0304553366360087,0.0325436460439968,0.0346263966841349,0.0366259021859564,0.0386470923898946,0.04083606301669,0.043073620143405,0.0576907009775252,0.0714936295396727,0.0849044719714465,0.0967701196602784,0.1096004644534754,0.1250264595063714,0.1397202411275259,0.1531101498071472,0.167153198815214,0.1801414937358425,0.1954135759875797,0.2053234822550591,0.2142001394092532,0.2233135148747933,0.2315530878886024,0.2412091506891848,0.250254118961184,0.2585898172235548,0.2658644942109509,0.2738362760834671,0.2811924746743849,0.2879488049416802,0.2948071918618405,0.3010782317000119,0.3068038282160901,0.3123559783613264,0.3169235392069712,0.3217976784441503,0.3253556897400679,0.3292412482179629,0.3290021139941023,0.3269881906020315,0.3257592832591424,0.3246582468714777,0.3245067574599682,0.3222472668169342,0.320724830513844,0.3209870454396001,0.3212781259632179,0.3221560527209972,0.3233356481915952,0.3241220950948177,0.3240278535173455,0.3250106366303155,0.3248939043209876,0.3269381772496466,0.3278187324989999,0.3308865225883687,0.3333216292134831,0.3341106719367589,0.3381662335293849,0.3413998510796723,0.3442695214105793,0.3450140930905767,0.343898724538359,0.3430506834401838,0.3462737761147489,0.3525508087930319,0.3558094176650878,0.3561275451402228,0.0,2.7463043418930133,59.73037618178561,172.96300581492727,264.0878171249927,fqhc4_implementation,30 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-100000,95717,44002,416.5090840707503,6286,64.50264843235789,4947,51.07765600676996,1968,20.1949496954564,77.35268390558021,79.74581498014027,66.18237796687838,68.08315149269112,77.10901752262856,79.50297651324654,66.07762478382753,67.98141197261593,0.2436663829516447,242.8384668937298,0.1047531830508461,101.73952007518494,123.68268,92.02483502657935,129217.04608376775,96142.62359516004,250.00684,176.6745285428373,260757.3785221016,184143.7033576452,261.8727,144.2627526302435,270504.6647930879,148216.9704569886,3340.29597,1759.9817581791997,3453447.9664009525,1802612.8340401505,934.49431,475.0703787750026,965497.0276962296,485574.2378818269,1734.65994,840.7376969774136,1782112.205773269,851918.9832966607,0.37785,100000,0,562194,5873.502094716717,0,0.0,0,0.0,29675,309.41212114880324,0,0.0,33078,341.43360113668416,1319722,0,57846,0,0,0,0,0,67,0.699980149816647,0,0.0,0,0.0,0,0.0,0.06286,0.1663623130872039,0.313076678332803,0.01968,0.3224681625227411,0.677531837477259,24.6810103149618,4.428332112041157,0.3147362037598544,0.2302405498281786,0.2288255508388922,0.2261976955730746,11.538737257510032,6.138791201945816,20.916861158079367,12262.961183882458,55.98799567958353,13.498283580584932,17.58613181634108,12.486155320117488,12.41742496254003,0.5591267434808975,0.7910447761194029,0.6917148362235067,0.5835567470956211,0.1192579505300353,0.706646294881589,0.9095744680851064,0.843520782396088,0.7035714285714286,0.1680327868852459,0.5060472787245739,0.7326343381389253,0.6376306620209059,0.5435041716328963,0.1058558558558558,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023207264177712,0.0044540492278971,0.006631798100848,0.0086416364209391,0.0111369003990552,0.0133939492783168,0.0156037922623968,0.0177077053552269,0.0197890126981203,0.0219186785260482,0.0238813628899835,0.0259071617219373,0.02773603935533,0.0299669096044615,0.0318983054347938,0.0340748094602839,0.0363525231282439,0.0386751227410967,0.0406685874166606,0.0425720389766036,0.0570569316235746,0.0716348870795571,0.0858809458864013,0.0981775735332779,0.1094921294295022,0.1248519333276927,0.1396133522908134,0.1527298667007367,0.1659240262862638,0.1788208037926485,0.1944211002650462,0.2044005067512695,0.2137516732508407,0.2223267619193488,0.2296639654716815,0.2389343263071569,0.2485601392981516,0.2572370419540294,0.2632725787048596,0.2703266236667545,0.2780098351171536,0.2845749967842651,0.2900851869380028,0.2954964887472138,0.3012228145377712,0.3065817514381798,0.3115145903198358,0.3165726797102741,0.3212191048331758,0.3253905425374709,0.3244287136974134,0.3215454420459233,0.3204501598659098,0.320127057464626,0.3190113053025132,0.3176290630975143,0.3159041738388895,0.3169609977250037,0.3169984686064318,0.3180160466812545,0.3192323488780196,0.3207941483803553,0.3222850702343929,0.3222732952516958,0.3240591559456535,0.3255777598290821,0.3261030038044404,0.3292698174543635,0.3337859480537567,0.3377182586710911,0.3396515931040708,0.341536519955829,0.3465749139818579,0.3516875237011755,0.3572564798353139,0.3601704949088326,0.3630632015992618,0.363876472978464,0.3701067615658363,0.3699421965317919,0.0,2.370317031788548,57.32235226778867,183.94841013735507,274.1226624580152,fqhc4_implementation,46 -100000,95681,44351,418.8814916232063,6238,63.816222656535786,4859,50.02038022177862,1921,19.596367094825517,77.28822072876713,79.65738721131477,66.17594254072044,68.05127127579294,77.0449482864884,79.41954901773283,66.0695588478442,67.95128718127565,0.2432724422787231,237.83819358193625,0.1063836928762356,99.98409451729628,123.2044,91.66981603570248,128765.79467187844,95807.75288270655,247.58281,175.29611921095497,258187.84293642416,182638.16140190308,259.82333,143.08141202320292,268507.0494664562,146964.04587647732,3231.18304,1698.8009226039085,3328912.981678703,1727359.7815699126,894.34066,457.6699815563075,919393.5577596388,463014.8317412787,1691.50367,822.5244180985125,1727061.1406653358,821063.2238703045,0.38187,100000,0,560020,5852.990666903565,0,0.0,0,0.0,29374,306.2049936769056,0,0.0,32906,339.8062311221664,1321073,0,57937,0,0,0,0,0,57,0.5957295596826956,0,0.0,0,0.0,0,0.0,0.06238,0.1633540210019116,0.3079512664315486,0.01921,0.3379204892966361,0.6620795107033639,24.51584968788953,4.352055553921836,0.331343897921383,0.2284420662687795,0.2226795636962338,0.2175344721136036,11.323985284230664,5.945910364404428,20.38201684683996,12391.025850265134,55.03955047596221,13.35116214953912,18.13558268548809,11.713604727286585,11.839200913648412,0.5571105165671949,0.7774774774774775,0.7024844720496894,0.5506149479659413,0.1210720887245841,0.7190923317683882,0.9025,0.8553921568627451,0.7231404958677686,0.1491228070175438,0.4993018709857582,0.7070422535211267,0.6505823627287853,0.4993865030674846,0.1135831381733021,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022784117950847,0.0046218870678383,0.0070614733723608,0.0094052165434305,0.0117318151781629,0.013953488372093,0.0160807092632222,0.0184499209143323,0.0207005067843714,0.0229598101006793,0.0250599348400713,0.0272624666529858,0.0295245044137746,0.0314783933460976,0.0334746155987996,0.0354906701382431,0.0377084994253647,0.0398277382867223,0.0419166658001185,0.0438960335160597,0.0586705383442311,0.0732866459399763,0.0867398329626054,0.0995307535298697,0.1106047659736067,0.1262230402267847,0.1407942621298447,0.1549220812398876,0.1678190153563375,0.1806495917250555,0.1952688867334842,0.2046084546084546,0.2136279525416349,0.2228789072760704,0.2318810268151996,0.2409141793112621,0.2498017623605356,0.2581993062125512,0.2663425052827702,0.2729588616673361,0.2796393096813825,0.2871447141903523,0.2938124178128443,0.2997542113782147,0.305505568795292,0.3095948879897365,0.3142864297071601,0.3195342326291677,0.3233563206471015,0.3277358665063615,0.3264483423440428,0.3244494029172348,0.3230921145436592,0.3224280133121111,0.3213239122350316,0.3201373243214247,0.3186266746904,0.3197697368421052,0.3211461435760501,0.3214713613848107,0.3231532089930692,0.3243597119447696,0.3254003324705932,0.3263815538126166,0.3267491900778492,0.3282709054663729,0.3305924822369929,0.3341451072174078,0.3363439946162292,0.3400216702114852,0.3445227241331676,0.3465432299279952,0.346310022558814,0.3472459270752521,0.3515302695960856,0.3542043672336832,0.3594333748443337,0.3632250102838338,0.3576912141029286,0.3571996817820206,0.0,2.8845195685939453,55.32687700448705,179.6981022044631,272.9963691409628,fqhc4_implementation,47 -100000,95576,44553,421.2040679668536,6196,63.739851008621415,4867,50.3473675399682,1942,19.900393404201893,77.21810735701168,79.67184396964072,66.1142194635241,68.06194613849688,76.96630041190151,79.42379003829853,66.00449705268196,67.95683077556717,0.251806945110161,248.05393134218437,0.1097224108421386,105.11536292970902,122.8634,91.47359121843633,128550.01255545329,95707.24639913396,247.67163,175.7935637425922,258698.76328785476,183493.8412808573,263.33462,145.80255234957008,272949.38059763954,150426.8439396498,3271.25841,1739.896077027906,3381050.1694986187,1778839.0655895907,888.0953,459.0462790215789,917345.860885578,468437.1170812546,1712.37461,848.0781031230554,1754637.1369381433,853447.6239180864,0.38149,100000,0,558470,5843.182388884239,0,0.0,0,0.0,29369,306.666945676739,0,0.0,33250,344.53210010881395,1318446,0,57891,0,0,0,0,0,65,0.669624173432661,0,0.0,0,0.0,0,0.0,0.06196,0.1624157907153529,0.3134280180761782,0.01942,0.3295279234804072,0.6704720765195927,24.48937630039127,4.3843151507761,0.3135401684816108,0.2315594822272447,0.2266283131292377,0.2282720361619067,11.081057497143505,5.778586288784695,21.006121945508447,12386.96145770462,55.57383300375647,13.552476419667986,17.371607068227593,12.43075493972051,12.218994576140387,0.552496404355866,0.782608695652174,0.6847968545216252,0.5787578757875788,0.1078875793291024,0.7228826151560178,0.9175,0.8423529411764706,0.754325259515571,0.1293103448275862,0.4873615450156205,0.7083906464924347,0.6239782016348774,0.5170316301703163,0.1021814006888633,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023414218816517,0.0044640592502409,0.0066833920754065,0.0094152575977875,0.0117041198501872,0.0140628343744586,0.0164294096637583,0.0188314873094372,0.0209343728896801,0.0230904769709883,0.0249879421634324,0.0270992680319105,0.0292890907405691,0.0314878607231997,0.0334304427777433,0.0357959660978361,0.0378618230073816,0.0399571961393411,0.042082248828735,0.0441624577367784,0.059172340225269,0.073813266268469,0.0865328068554146,0.099222097074706,0.1111744162736471,0.1265186470812344,0.1411980764535408,0.1548418024928092,0.1676982777973766,0.1806394830898689,0.1955005551543113,0.2050385036120828,0.2138416141290737,0.2227515661278311,0.2308251785241999,0.2405077336173801,0.2496786668305931,0.258050341393064,0.2653545901844255,0.2723102155038937,0.2796088835339504,0.286154206428195,0.2923747379889392,0.2986506278662152,0.3044578855772858,0.3101680256980479,0.3155636409259143,0.3206794098519529,0.3250924664200895,0.3282383145413159,0.3274272894366958,0.3257709738034707,0.3245242979415718,0.3237352616599872,0.3229818301258603,0.3204076291929003,0.3186729132804283,0.3180773491625192,0.3187936792095569,0.3204325452517183,0.3205322044148775,0.3224873319235526,0.3229160063391442,0.3240811724915445,0.3260880124344278,0.3277124940717711,0.3292030818767249,0.3325529895602657,0.3359776180189113,0.3386677335467093,0.3423724163160783,0.343445633083187,0.3449661059502887,0.347285757853004,0.346600018862586,0.3477286135693215,0.3505676587910402,0.3587489779231398,0.3640387275242047,0.3612828438948995,0.0,2.186158781718143,59.11141182225192,179.37550564436378,267.5429919064499,fqhc4_implementation,48 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-100000,95663,44199,417.7895320029688,6100,62.46929324817328,4798,49.41304370550788,1971,20.018188850443742,77.30933613681017,79.6949923005426,66.16754487630577,68.0564977029007,77.06005668292114,79.45236669469742,66.05908715028511,67.95468339996978,0.2492794538890308,242.625605845177,0.10845772602066,101.81430293091864,123.39998,91.74187891733814,128994.24019735948,95900.88008669822,247.53015,175.52104148471872,258184.8781660621,182911.1479722764,258.52069,142.63575124172226,267411.00529985473,146636.50840936237,3254.42225,1722.0994588280937,3354217.889884281,1752425.3565412897,921.48296,473.2115425012507,947102.1398032678,478507.785142899,1735.67869,852.7495478225251,1765975.9154532056,847826.4405119151,0.37989,100000,0,560909,5863.374554425431,0,0.0,0,0.0,29421,306.7643707598549,0,0.0,32746,338.4589653261972,1318346,0,57879,0,0,0,0,0,57,0.5958416524675162,0,0.0,0,0.0,0,0.0,0.061,0.1605727973887178,0.3231147540983606,0.01971,0.3374357376538401,0.6625642623461598,24.77569018130772,4.351445487318098,0.3092955398082534,0.2363484785327219,0.2365568987077949,0.2177990829512296,11.349820974336607,6.005009936232099,21.17986975278656,12315.069812114907,54.71268721752166,13.681554796964363,16.83919492400631,11.66972191644515,12.52221558010585,0.5623176323468112,0.798941798941799,0.717654986522911,0.5626794258373206,0.1224669603524229,0.7330350484712901,0.937354988399072,0.8772845953002611,0.7345454545454545,0.1626984126984127,0.4960948799537171,0.7140825035561877,0.662125340599455,0.5012987012987012,0.1109852774631936,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0020451761180127,0.0045088860518369,0.0066245320726771,0.0089275739140149,0.0113701082092588,0.0134489885261089,0.0156562155991356,0.0177410299596794,0.0200134922419608,0.0225018171394641,0.0243089730971128,0.026711716800345,0.0289061937435063,0.0309382471761892,0.0328977249267104,0.0350173225089198,0.0371191709844559,0.0391379274546851,0.0413788799201131,0.043444724718047,0.0583030379006309,0.0728032333724242,0.0859949828387895,0.0986075589656152,0.1109575164088386,0.1251891594442151,0.1401261039402173,0.1538461538461538,0.1667112199399065,0.1797665954500069,0.1944255755027225,0.2041267501842299,0.2129838437319562,0.22261046728153,0.2305073166431593,0.2399139202875239,0.2489131770990489,0.2576129832074834,0.264798145117294,0.2725019791415689,0.2792216075798165,0.2860474655728098,0.2925709812851348,0.2989469133875286,0.3050091950943258,0.3096673006150122,0.3145278571786771,0.3193322288772779,0.3224329966417281,0.3253659954547857,0.3250300079571662,0.323688595706003,0.3224090742360543,0.3217057631045468,0.3207210157331467,0.3182550520937227,0.3160281618673094,0.3171689617773688,0.3174367126472147,0.3179349767774205,0.3185101791912937,0.3187419641974087,0.3192029898379104,0.3209284610041897,0.3228714685179828,0.3231572080887149,0.3254549078793746,0.3289651488011061,0.3318277310924369,0.3338744160266054,0.3368085590712497,0.3384060660692508,0.3369894099848714,0.3408003644923684,0.3442853131142937,0.3442507068803016,0.3446293494704992,0.3489353153877059,0.3593109105824446,0.3667041619797525,0.0,2.8124157654286384,58.48274411368534,176.34428869396265,259.3096055986675,fqhc4_implementation,55 -100000,95624,44206,417.4579603446834,6198,63.4777880030118,4850,50.06065422906384,1946,19.94269221116038,77.2636987819685,79.67440702961206,66.13567096343145,68.04448285320393,77.01381074598496,79.42694707017394,66.02592738363676,67.93909635854608,0.2498880359835453,247.4599594381175,0.1097435797946957,105.38649465785,122.85306,91.35082646008374,128475.13176608382,95531.27505655876,247.28587,175.19732524650465,258104.4193926211,182716.9175588813,259.50314,143.04496167143265,268551.9221116038,147248.77272733467,3261.71655,1730.8284510436,3366736.133188321,1765790.660340079,886.73876,461.034503127378,912250.0,467064.4222448116,1713.72421,849.7748937339327,1756564.3248556848,855331.9257914918,0.37997,100000,0,558423,5839.778716640174,0,0.0,0,0.0,29315,305.8750941186313,0,0.0,32764,338.7956998243119,1320215,0,57951,0,0,0,0,0,68,0.7111185476449428,0,0.0,0,0.0,0,0.0,0.06198,0.163118140905861,0.3139722491126169,0.01946,0.3416666666666667,0.6583333333333333,24.739812378522007,4.323680237862245,0.3261855670103092,0.2268041237113402,0.2278350515463917,0.2191752577319587,10.935617780448526,5.694045140613647,21.03758399128405,12368.93130092855,55.408101108769735,13.254803790495297,18.055948402601583,11.808896022861758,12.288452892811096,0.5527835051546391,0.7709090909090909,0.6890012642225032,0.5860771401693321,0.1085972850678733,0.7250372578241431,0.9243498817966904,0.8459715639810427,0.7132075471698113,0.1551724137931034,0.4868871151653364,0.6750369276218612,0.631896551724138,0.543859649122807,0.0962199312714776,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024003646123461,0.0048753788301117,0.0069719296109115,0.0093463640611983,0.0117267752893553,0.0140123626513508,0.0163128810587059,0.0185897893973886,0.0208778512785383,0.0229683787990497,0.0252193094957164,0.0273736128236744,0.0294865329394934,0.0316414586619653,0.0340150810866646,0.0357796931099775,0.0378330741316744,0.0398699396445155,0.0418097795541122,0.0437395032494288,0.057643062451006,0.0722309546264277,0.0855435227881474,0.0982046905619824,0.1106052603781557,0.1259310271759283,0.1409652768182639,0.1546712728978738,0.1679292118722047,0.1802570495185694,0.1957514329199184,0.2060957752589619,0.2153237323797791,0.223667043099762,0.2320250623248836,0.240454454587859,0.2495495797943174,0.2585823715887682,0.2655569083027069,0.2722920613053212,0.2794167121031078,0.2847487855818646,0.2911448007313048,0.2978418996092576,0.3034478557504873,0.3085191820596775,0.3132886781565941,0.3179033616662838,0.3228303504169156,0.326730708161321,0.3266606373931941,0.3253989049937251,0.3241766001920795,0.322720820417741,0.3217138599105812,0.319518634493768,0.317697431018078,0.3197193768321201,0.3204334630750501,0.3209337295478142,0.3217848755284171,0.3234571813356571,0.3231021162243869,0.3239089524150909,0.3258367445220322,0.3274806575142626,0.328069775396192,0.3316387372120755,0.3351677240702443,0.3394047619047619,0.3429967129291453,0.347668724717905,0.3484858064108238,0.3486168424270212,0.3492963067913479,0.3525222551928783,0.3525984976237927,0.3555018137847642,0.3643858202802967,0.3653846153846153,0.0,2.4662264929393034,58.870337155431606,181.99742402031268,261.2121660639598,fqhc4_implementation,56 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-100000,95754,44162,416.8703135117071,6171,63.26628652588926,4868,50.27466215510579,1915,19.65453140338785,77.33863470024116,79.70815831521158,66.18619024641207,68.06752782279743,77.09787260415186,79.46851071954912,66.0819668727192,67.9666071628829,0.2407620960892984,239.6475956624613,0.1042233736928608,100.9206599145358,122.65264,91.2218321383997,128091.40088142532,95266.86314764888,247.27783,174.54750914138936,257838.24174447023,181882.8551719921,259.43916,142.79401663912915,268264.20828372706,146886.65621321104,3284.27574,1718.7432493394815,3395016.4797293064,1760063.902645826,902.88844,458.6669279416147,933236.6480773648,469317.11254006665,1683.01089,822.2313502768682,1728962.0485828267,832035.7058880235,0.37982,100000,0,557512,5822.336403701151,0,0.0,0,0.0,29304,305.4702675606241,0,0.0,32734,338.2417444702049,1327751,0,58247,0,0,0,0,0,72,0.7519268124569208,0,0.0,0,0.0,0,0.0,0.06171,0.1624716971196882,0.3103224760978771,0.01915,0.3298841698841699,0.6701158301158301,24.681039795540286,4.505981330631769,0.3412078882497946,0.2128184059161873,0.2228841413311421,0.2230895645028759,11.279227286287844,5.781685950961242,20.41172885242428,12382.619749448888,55.2077441838225,12.456686836268045,18.76998193190676,12.01413846633634,11.96693694931134,0.5552588331963846,0.7615830115830116,0.7194461167971101,0.5478821362799263,0.1142857142857142,0.7153846153846154,0.9064935064935064,0.8648018648018648,0.720164609053498,0.1440329218106996,0.4969170403587444,0.6758832565284179,0.6688311688311688,0.498220640569395,0.1057007125890736,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023610238534341,0.0045845504706264,0.0070554794172884,0.0094619590625444,0.0116598498260179,0.014096844506916,0.0164108317609261,0.0185890692187484,0.0209255944771158,0.0229747308689016,0.0249787142373542,0.0268732151295379,0.0289006636143834,0.0308683329038907,0.0331650822159601,0.0351947393997043,0.0370642695884509,0.0391271867023594,0.0413712075526627,0.043362776550977,0.0586258011984049,0.0728999926765219,0.0862027374272379,0.0991649488872996,0.1109236431124843,0.1270041033884682,0.141368700265252,0.1547967514289668,0.1679736746511677,0.1809445153540055,0.1957336377145564,0.205885534999459,0.2147756797008338,0.2238838602474966,0.2317370933327467,0.2407110028240766,0.249475937736943,0.2584605698095388,0.2658559549873515,0.2736667239502778,0.2807640688633839,0.2877040744725639,0.2937578381959726,0.299327878083554,0.3051798246679132,0.3103473780232242,0.3148029898959546,0.3188733971097089,0.3220003108486167,0.3265834147371756,0.3256377791546564,0.324874772939946,0.323664961312418,0.3231851809039417,0.3226026990071934,0.3208351217119382,0.318744053282588,0.3189963569529686,0.3193284487028403,0.319943559334143,0.3207589578377568,0.3220298790609438,0.3227436671699379,0.3236032080290336,0.3242039902770089,0.324763793913452,0.3256940881363662,0.3296503233096867,0.3330530151722204,0.3369185585013494,0.3400344890179706,0.3431918163990035,0.3463008206477479,0.3517272658553179,0.3580327868852459,0.362962962962963,0.3678960096735187,0.3651335609560153,0.3717462039045553,0.376860119047619,0.0,2.242227168653341,57.15192118106173,182.4381520880538,266.4679411225378,fqhc4_implementation,58 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-100000,95641,44502,421.9320166037578,6191,63.55015108583139,4880,50.46998672117606,1952,20.054160872429183,77.35980074479698,79.76713385869068,66.19799339355062,68.10297145116017,77.11812691698928,79.52460907678366,66.09319351444738,67.99987095127116,0.2416738278077019,242.5247819070222,0.1047998791032398,103.10049988900973,122.89882,91.46779879411002,128500.14115285286,95636.59810553008,248.78702,176.34097983096902,259700.62002697584,183952.72930120863,262.03204,144.84389285658068,271151.32631402847,149064.16703180867,3298.96236,1735.6334514670853,3415614.6422559363,1781172.5519918038,908.21497,465.3501355463048,936611.756464278,473585.8048594514,1725.46854,844.1702540680209,1774548.7500130697,856825.0874659872,0.38214,100000,0,558631,5840.915506947857,0,0.0,0,0.0,29554,308.4242113737832,0,0.0,33105,342.3322633598561,1322766,0,57930,0,0,0,0,0,58,0.6064344789368575,0,0.0,2,0.0209115337564433,0,0.0,0.06191,0.1620086879154236,0.3152963979970926,0.01952,0.3347738848587745,0.6652261151412255,24.431614441859725,4.391544770502739,0.3133196721311475,0.230327868852459,0.230327868852459,0.2260245901639344,10.913329812139631,5.408271989324293,20.82303743631248,12360.85284360246,55.16846690822222,13.36545071783904,17.286926663091794,12.147964698200129,12.36812482909126,0.5479508196721311,0.7935943060498221,0.6697187704381949,0.5702629193109701,0.1147686832740213,0.7141768292682927,0.9331742243436754,0.83,0.7298387096774194,0.1346938775510204,0.4868273542600896,0.7106382978723405,0.6129317980513729,0.5239766081871345,0.1092150170648464,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023399513776337,0.0045519982156978,0.0069218902240987,0.0090520262925297,0.0111364237332953,0.0133056429364037,0.0153259828397904,0.0175327591133608,0.01961666240736,0.0218459522542074,0.0238056182079147,0.0258474619784553,0.0281346761169003,0.0300032970656116,0.0320786070370638,0.03421534261873,0.0362826357231661,0.0383397527070377,0.0404608035965158,0.0424466809198519,0.0573826169650228,0.0717704351468817,0.0857583774250441,0.0984500121010596,0.1112388951022389,0.1263412982285339,0.1411719737107546,0.155540408128488,0.1687957667432786,0.1821839758790519,0.197097045322299,0.207194338029998,0.2161327504838955,0.2249592722581209,0.2332435255952053,0.2432390546299883,0.2521939850797863,0.2604173694034046,0.2674435757486355,0.2749899730705323,0.2822661866339442,0.288934666073644,0.294837648117239,0.3002564655688982,0.3056247493833311,0.3106505227855592,0.3146486452662537,0.3193838482770902,0.322267520869734,0.325682324851267,0.3251460256789857,0.3236110729306979,0.3225085089027031,0.3219307480422838,0.3211480899742169,0.3187834326761424,0.316782255643849,0.3172769722290489,0.3178227113727497,0.3181769608890789,0.319710999925323,0.319561667551988,0.319549577729121,0.3205459322260319,0.320571291406625,0.3197000859128895,0.3214885202992972,0.3264543284332202,0.3306893162993121,0.3333200779417027,0.3357717629846379,0.3391915641476274,0.34375,0.346139158328878,0.3481857492009776,0.3486943164362519,0.3476132190942472,0.3458767013610889,0.3465400271370421,0.3514739229024943,0.0,2.155680323655529,57.71632124739608,178.30980796743287,269.6212033334087,fqhc4_implementation,67 -100000,95808,44235,418.1696726786907,6049,61.706746826987306,4767,49.03557114228457,1887,19.25726452905812,77.37785538535894,79.69115578947915,66.22790251095267,68.06169952584038,77.13147217121451,79.44755300027464,66.12131865676498,67.95906132732603,0.2463832141444299,243.60278920451609,0.10658385418769,102.63819851435584,122.474,91.13344047043758,127832.74883099532,95120.90897465512,245.50143,174.52117796548535,255718.8126252505,181632.87822048823,259.29121,143.4437212033268,266685.82999332,146419.6722925446,3195.10553,1702.7475059056562,3292946.434535738,1735291.5162675933,890.21708,459.4673059992217,917887.6503006011,468290.7752997899,1665.61775,819.4722490488631,1702774.2150968604,825027.6234536101,0.3796,100000,0,556700,5810.579492317969,0,0.0,0,0.0,29213,304.1708416833667,0,0.0,32839,337.46659986639946,1328113,0,58181,0,0,0,0,0,52,0.542752171008684,0,0.0,0,0.0,0,0.0,0.06049,0.1593519494204425,0.3119523888245991,0.01887,0.3338063702302113,0.6661936297697887,24.29765513465834,4.430137676567888,0.3215859030837004,0.236836584854206,0.2290748898678414,0.2125026221942521,11.407681330839,5.932092026263385,20.21256458695008,12325.006343547298,54.444692409265,13.641670608041542,17.52995579599959,11.25461487304714,12.01845113217672,0.5638766519823789,0.79185119574845,0.7012393998695369,0.579466929911155,0.1208791208791208,0.7265336289726534,0.928735632183908,0.8356807511737089,0.7420634920634921,0.15,0.4994141769185706,0.7060518731988472,0.6495031616982837,0.5256241787122208,0.1126760563380281,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023190343095556,0.004611938331796,0.0068480642804967,0.0090690282023419,0.0114567449425637,0.0134765127996335,0.0157863090203112,0.0180007347238662,0.0198975994113499,0.022053706660117,0.0242135464699252,0.0263535979639587,0.0285655548131777,0.030841448601017,0.0327907719902277,0.0345952867794369,0.0367361721943395,0.0387418488684311,0.0406382448267265,0.042731039077301,0.0575386476957419,0.0715002613695765,0.0847331523960221,0.0975207479777287,0.110509403150187,0.1255481239631872,0.1398240407038372,0.1532424442223025,0.1666239699415055,0.1797564948983966,0.1948289595487718,0.2040083498274873,0.2139728022784342,0.2228793825365416,0.2309985916732682,0.2401696905252431,0.2486800245576826,0.2570972420538996,0.2648989355069095,0.2729155937052933,0.2795620606733259,0.2858745049476033,0.2923327779943993,0.298702542251161,0.303634886174819,0.3091334030383172,0.3143692376883292,0.3184093507813492,0.3223515715948777,0.3264810981157452,0.326267591407986,0.3245279380775958,0.3238044198739193,0.3226763110307414,0.3212072578128483,0.319258669768296,0.3175427485750475,0.3182243220630936,0.3183362644492632,0.3191014844419069,0.3200613416618353,0.320524207077585,0.3223445527943798,0.3244785605585892,0.326798015318657,0.3276763767585377,0.3298191480243421,0.3330598851517637,0.3355232948323973,0.3365645444391256,0.3395984817304614,0.3438351043947242,0.3464840297942179,0.3478128101381785,0.35268192048012,0.3505154639175257,0.3461064943059403,0.3458646616541353,0.3436807095343681,0.3384088313665778,0.0,2.8239034811222923,58.75155445993084,173.58212279974464,258.11630769708626,fqhc4_implementation,68 -100000,95745,44105,417.410830852786,6111,62.60379132069559,4757,49.07828085017494,1850,18.96704788761815,77.34679063643568,79.70251324500684,66.19748415901273,68.06492970133098,77.1123984285971,79.47028248377053,66.09608398719817,67.96749935934668,0.2343922078385816,232.23076123630904,0.1014001718145607,97.43034198430678,123.6851,92.01935377907196,129181.78494960572,96108.78247331134,247.4483,175.27017807703206,257991.07002976656,182605.2828628461,259.28079,142.7194503311009,267701.9896600345,146533.7150562736,3187.41809,1681.7808152764308,3290612.6272912426,1718063.3821885518,875.71453,448.52431375584825,902490.156143924,456315.1953165684,1631.23598,798.1754678654904,1673394.1824638362,805669.1744312149,0.37972,100000,0,562205,5871.899315891169,0,0.0,0,0.0,29390,306.33453444044073,0,0.0,32814,338.64953783487385,1321132,0,57935,0,0,0,0,0,62,0.6371089874144864,0,0.0,0,0.0,0,0.0,0.06111,0.1609343726956704,0.302732776959581,0.0185,0.3248477276276745,0.6751522723723254,24.580416720090486,4.25787240892294,0.3258356106789993,0.2333403405507673,0.2257725457220937,0.2150515030481395,11.0886887696512,5.726578311468665,19.793681130061103,12274.171263658687,54.08559715756655,13.469994842231683,17.50752183170414,11.30555809977472,11.802522383856015,0.5631700651671221,0.7972972972972973,0.6987096774193549,0.5786901270772239,0.1108007448789571,0.7235202492211839,0.9152542372881356,0.859375,0.7073170731707317,0.1950207468879668,0.5038871292830406,0.727403156384505,0.6457975986277873,0.5379665379665379,0.0864345738295318,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022886771243683,0.0044288595433308,0.0065351518103588,0.0088493776987553,0.0109754857084731,0.0132409859441841,0.0154313747488449,0.0174947658683552,0.0197463953369465,0.0218117025416265,0.0237687519867108,0.0259947004087669,0.028093239517755,0.0302602567536936,0.0323256510026938,0.0342820515471378,0.0363979118329466,0.038689456915429,0.0406962235900848,0.0425724732034041,0.0571875978703413,0.0707829434657069,0.0842184731207599,0.0967287410227021,0.108780919845638,0.1246906267848454,0.1399783522220807,0.1538617171943051,0.1668144665847534,0.17963211240414,0.1945353896523499,0.2045501282564696,0.2126976875720594,0.2227460159471491,0.230126766142876,0.2395914116682546,0.2484313944401027,0.2577577183247605,0.2657891449273716,0.2725470422406087,0.2795212242582796,0.2859165808444902,0.2921345652688936,0.297172415448501,0.3031784841075794,0.3072815833281953,0.3119100673493403,0.315949476576313,0.3205090033527942,0.3236768508258139,0.322732959360749,0.3214663570535456,0.3207120059615033,0.3207568939656167,0.3206786693339261,0.3187198730856062,0.3167689129303411,0.3167787211071305,0.3172430232756125,0.3185100857376641,0.3200029871924125,0.3211488765707297,0.3219423330611219,0.3221819158941287,0.322491199305589,0.32257895974294,0.3244424136847816,0.3282577235260807,0.3311514639639639,0.3349005857273778,0.3380146824130227,0.3415384615384615,0.344354532810722,0.3454823889739663,0.3493601806548739,0.3509649749821301,0.3541954287467403,0.3569553805774278,0.3630590833793484,0.3640985529917872,0.0,2.3113372084739625,56.26132482248549,177.6023533109271,260.88239821679343,fqhc4_implementation,69 -100000,95792,44047,417.56096542508766,6210,63.8257892099549,4884,50.536579255052615,1896,19.53190245531986,77.33632654933726,79.66828103013951,66.20418950728282,68.05231665272906,77.10409081011123,79.43511559599236,66.1044493666603,67.95411286288261,0.2322357392260272,233.1654341471534,0.0997401406225151,98.20378984645116,123.96868,92.2677016301109,129414.43961917488,96320.8844476688,249.41681,176.32391128181655,260039.5231334558,183735.76215322415,261.55178,143.91367992844846,270822.22941372974,148354.55553376192,3278.54174,1716.7706133537104,3394947.7722565555,1764570.364282728,885.36326,447.0303540598285,915583.2011023886,457994.9829420291,1668.77303,805.2631839786925,1720271.2543844995,820783.1420424792,0.37887,100000,0,563494,5882.474528144313,0,0.0,0,0.0,29660,309.1698680474361,0,0.0,33066,342.1997661600134,1317948,0,57791,0,0,0,0,0,62,0.6472356773008184,0,0.0,2,0.0208785702355102,0,0.0,0.0621,0.163908464644865,0.3053140096618357,0.01896,0.3368876526039252,0.6631123473960748,24.51973258543473,4.391221525579111,0.3257575757575757,0.2305487305487305,0.2207207207207207,0.2229729729729729,11.164281719236298,5.744312351509187,20.180530718517748,12240.106684969523,55.41219785030928,13.5256215571713,18.002314547652258,12.111179603604992,11.77308214188072,0.5632678132678133,0.7770870337477798,0.7184160905091138,0.581267217630854,0.0927643784786641,0.7511591962905718,0.9326923076923076,0.8867924528301887,0.7330677290836654,0.1182266009852216,0.4955431754874652,0.6859154929577465,0.6572407883461868,0.535799522673031,0.0868571428571428,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023896556263226,0.004671855365033,0.0067872614566741,0.0087446678854357,0.010857520459513,0.0129497281778755,0.0151353004127809,0.0174283935878205,0.0195042707098778,0.0214555388440406,0.0236463295937708,0.0259057785076465,0.0279159643136126,0.0298714938836031,0.0318563986176303,0.0335744548930453,0.0356969075793811,0.0375364318089884,0.0394816154309825,0.0414119852137241,0.0564872113287486,0.070986233733629,0.084412520316678,0.0976861050661788,0.1105559947299077,0.1254267383974718,0.1401957353861161,0.1541177847030919,0.1676309833895554,0.1799099967855995,0.1945766142054384,0.2033914802037483,0.2128260869565217,0.2215397394421614,0.2286550157825852,0.2378348461368164,0.2464977246363879,0.2550913691312904,0.2628402219171554,0.2704483220861355,0.2775566406701997,0.2840202086354493,0.2897396449704142,0.2959478408859379,0.3010917402193206,0.3062127806477862,0.3108275628905222,0.3154912720744579,0.3195402596394041,0.3243335927298627,0.3239330498896722,0.3224710445954497,0.3219058359176769,0.3204050632911392,0.3201916923397478,0.3173582879496817,0.3150365565476662,0.3158794895408499,0.3167420039723306,0.3177255729902846,0.3198647506339814,0.3196011181380226,0.3207912050953271,0.3217090794847628,0.3237179487179487,0.3260523500091338,0.3287541856272001,0.3319127442623986,0.3357082392776523,0.3387636421572532,0.3407144158921086,0.343928798474253,0.3463469746422294,0.3483963909318371,0.3505368242606894,0.3529691211401425,0.3531764343947085,0.3587203302373581,0.3671279299632872,0.3665369649805447,0.0,1.7757663332850486,57.11953198207466,187.75886724990332,264.26865578685585,fqhc4_implementation,70 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-100000,95792,44087,416.89285117755134,6078,62.35385000835143,4760,49.14815433439118,1862,19.156088191080677,77.39095688547141,79.73016183088085,66.22920496418115,68.08385478236636,77.15267159808955,79.4910453436735,66.1252696231147,67.9821349199368,0.2382852873818564,239.1164872073404,0.103935341066446,101.71986242956166,123.1967,91.6817975368407,128608.54768665442,95709.24245953806,246.16933,174.5074356368772,256583.6708702188,181773.7761367099,258.79854,142.6398558613058,267561.40387506265,146723.55939783584,3177.84479,1681.2191419868168,3285535.6919158176,1723165.5065003503,861.55282,441.5141321978324,890886.0343243695,452404.56179099466,1633.99682,803.5759747874071,1682126.3779856355,816630.5380146548,0.37855,100000,0,559985,5845.8430766661095,0,0.0,0,0.0,29232,304.59746116585933,0,0.0,32700,337.8883414063805,1326940,0,58108,0,0,0,0,0,61,0.6263571070653081,0,0.0,0,0.0,0,0.0,0.06078,0.1605600316999075,0.3063507732806844,0.01862,0.3369445752865442,0.6630554247134558,24.62586302588601,4.408144058477292,0.3178571428571428,0.2331932773109243,0.2115546218487395,0.2373949579831932,11.349717497518954,5.886418398849492,19.9574564603345,12246.776519148603,54.07985857436452,13.21265937115756,17.112690437716708,12.629184447875378,11.125324317614872,0.5630252100840336,0.7792792792792793,0.6893588896232651,0.5823008849557522,0.1132075471698113,0.7315384615384616,0.9236453201970444,0.8647214854111406,0.7403508771929824,0.168103448275862,0.4997109826589595,0.6960227272727273,0.6311619718309859,0.5289940828402366,0.0967741935483871,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023804459031006,0.0043492366025264,0.0067995453438337,0.0089709333631348,0.0110660197927155,0.0133477229456622,0.0158545662170291,0.0178775626888834,0.0203042571463624,0.0224069278249209,0.0246042811449192,0.0267975399652966,0.0287171367174246,0.0304456643767187,0.032550605616656,0.0346523909426318,0.0366573470021745,0.0385425420440515,0.0405055660073381,0.042548980803483,0.0574749825216783,0.0711178500470563,0.0847859126880142,0.097211858795834,0.1093056828839081,0.1249881099590982,0.1391000159007791,0.1528464622616427,0.1655887124316939,0.1781976713047763,0.1927608431336683,0.2020988014568405,0.2109195964071986,0.2202066314271984,0.2286072166307739,0.2378755186721991,0.2467682981189266,0.255777116216368,0.2631209209572154,0.27078922976576,0.2781084235707434,0.2847928205847297,0.2904255696531826,0.296475069169132,0.3022776085716712,0.3073987443062907,0.3128523041157869,0.3173139220244674,0.3211513583441138,0.3244379431222161,0.3239499132493174,0.3226298433635614,0.3210455198040706,0.3206906516399364,0.3201384350305983,0.3179626142470032,0.3160160825656124,0.3168162501845866,0.3173027729458713,0.3177556767547143,0.3186794708915627,0.3196426111428178,0.3202186248331108,0.3212393714107643,0.3224862011039117,0.3230945738051159,0.3241271198517885,0.3271368460717201,0.329727451531329,0.3335853260653324,0.3370206152580335,0.3389668367346938,0.3418619379354021,0.3443086325439267,0.3481481481481481,0.3533096926713948,0.3516383495145631,0.3522884882108183,0.3469333333333333,0.3511111111111111,0.0,2.11110234318953,57.13550416457413,176.58512670763417,259.2911410303089,fqhc4_implementation,77 -100000,95625,44361,420.05751633986927,6209,63.74901960784314,4904,50.645751633986926,1914,19.607843137254903,77.2981730373493,79.74318771355334,66.15422193859041,68.09657406868254,77.05627826485194,79.50263701012261,66.04914932121254,67.99476648227139,0.2418947724973605,240.5507034307277,0.1050726173778713,101.80758641115516,123.61624,91.97428680244528,129271.88496732026,96182.26070843951,248.24977,176.11338669267357,259158.6091503268,183721.8684367828,265.51274,146.69799522661197,274792.61699346406,151012.79377210516,3293.90942,1741.1851191389242,3407948.4967320263,1784184.521975347,916.81987,468.3708928849802,947504.3137254902,478538.0631476917,1679.73239,821.2662928042432,1723675.440522876,828719.3075164758,0.38097,100000,0,561892,5875.99477124183,0,0.0,0,0.0,29501,307.8692810457516,0,0.0,33577,347.2313725490196,1318200,0,57853,0,0,0,0,0,63,0.6588235294117647,0,0.0,0,0.0,0,0.0,0.06209,0.1629787122345591,0.3082622000322113,0.01914,0.335686876438987,0.664313123561013,24.6497139228055,4.337710131279088,0.324836867862969,0.2340946166394779,0.2169657422512235,0.2241027732463295,11.172790196894924,5.753668643076315,20.480814289403668,12372.549910968712,55.92492463623057,13.90577441067953,18.19297257397327,12.221603655214802,11.604573996362976,0.5681076672104405,0.789198606271777,0.6961707470182047,0.5814376706096451,0.1240601503759398,0.7350611951043916,0.9051918735891648,0.8508771929824561,0.740072202166065,0.1267605633802817,0.5021337126600285,0.7163120567375887,0.6341248900615655,0.5279805352798054,0.1233842538190364,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023015309743485,0.004465327744908,0.0064610508350603,0.0088782670599003,0.0113124936360859,0.0134789302501045,0.0157424044429924,0.0180626827223846,0.019927536231884,0.0221395406045324,0.0243757248570812,0.0265319339220181,0.028790609071719,0.0306889546574819,0.0326175647341947,0.0349818934299017,0.0369932730080744,0.0390271258256137,0.0409225261229757,0.0429445933403551,0.0574955318415084,0.0723817903756311,0.0848628669830736,0.0978867162011408,0.1101975767298518,0.1256521233028921,0.1406128926111093,0.154982060536374,0.1684509690792144,0.1819595812237192,0.197347440096535,0.2069700972219214,0.2156389342033714,0.224541138894358,0.2330146225532804,0.242036241194453,0.2505325615373462,0.2586778811015033,0.2660459947382745,0.2729593296780028,0.2810012955765315,0.2879794200187091,0.2939639682239455,0.2999964063679161,0.3055039296429916,0.3103571516600527,0.314580596734847,0.3195518364024824,0.3228215982497702,0.3271146411937778,0.3266592160717411,0.3250392227023754,0.3229917755745831,0.3230153107695866,0.3217651080526738,0.3197216486961841,0.3184681120430447,0.3195417767638804,0.3203083602550297,0.3205906510016784,0.3218063694744528,0.3216341982806215,0.3224234565835703,0.322910617769241,0.322809464268539,0.3243757990033656,0.3252627681089241,0.3295836606441477,0.3330050647158131,0.3362884868815143,0.3381962864721485,0.3416394845195444,0.3451547179421877,0.3482238966630785,0.3481955317930112,0.3519593613933237,0.3528131799813491,0.3511264461132535,0.3519289480988065,0.3512476007677543,0.0,2.5174220693944527,60.854340201042255,176.49087991667392,267.2649741788126,fqhc4_implementation,78 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-100000,95763,44349,419.9847540281737,6109,62.64423629167841,4879,50.40568904482942,1944,19.976400071008637,77.29075226531792,79.63010124584487,66.17497297535141,68.02874796983481,77.05067297914005,79.38894577024664,66.07201772912123,67.92715795521472,0.240079286177874,241.1554755982337,0.1029552462301808,101.59001462008632,123.45652,91.79225914706852,128918.80997880184,95853.57512511988,250.05454,176.94373473856848,260728.24577341985,184382.6788410644,262.1819,144.42201509385788,270814.75099986425,148379.8624046402,3266.07689,1725.4914287662066,3377711.443877071,1768963.324839663,906.37328,465.5536626887006,936477.783695164,476154.258626715,1714.99733,832.9907709239578,1763852.4900013574,846543.969879895,0.38138,100000,0,561166,5859.945908127355,0,0.0,0,0.0,29613,308.6787172498773,0,0.0,33200,342.80463226924803,1318750,0,57913,0,0,0,0,0,72,0.7414136984012614,0,0.0,0,0.0,0,0.0,0.06109,0.1601814463264985,0.3182190211163856,0.01944,0.3286494925839188,0.6713505074160812,24.39016776128372,4.301102767220001,0.3283459725353556,0.2303750768600123,0.2232014757122361,0.2180774748923959,11.40268051011524,6.0387067426730106,20.69610435316541,12374.337953368338,55.63216728662148,13.56919204955,18.105482374782763,11.898143844597945,12.059349017690778,0.5697888911662226,0.8078291814946619,0.6978776529338327,0.5958646616541353,0.1101928374655647,0.7484615384615385,0.9508599508599508,0.863961813842482,0.758893280632411,0.1447963800904977,0.504889633975971,0.7266387726638772,0.6390532544378699,0.5450061652281134,0.1013824884792626,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.002106115836371,0.0044695794946638,0.006857583411952,0.0089374581056651,0.0112346984423929,0.013226220294459,0.0151067256528918,0.0173184471567947,0.0197348922297055,0.0219658740800638,0.0238646847770374,0.0259750926581862,0.0281882783656763,0.0302034509399948,0.0322171198596563,0.0342796316773973,0.0364853954913366,0.0383318986527831,0.0401962006900278,0.0422529343762042,0.0562258636885502,0.0708980206720508,0.0845219616562486,0.0974963181148748,0.110411525237824,0.1259180088467481,0.1402683708783626,0.1539559456350389,0.1675237616670052,0.1802919708029197,0.1951947743979994,0.2047920140317446,0.2135680306543439,0.2236133607669745,0.2319178926966787,0.2415368409380717,0.251010879521033,0.2589181154850914,0.2663137326183768,0.2734100003439696,0.2811269171956814,0.2874084490537294,0.2941371668306095,0.3013365006238602,0.3063375145857643,0.3117345555801976,0.3170081813405389,0.3216978852732104,0.3251987260816654,0.3291139240506329,0.3284645961059085,0.3265789654934913,0.3255692412000678,0.3243936736202722,0.3236521946564885,0.3218973838728519,0.3199485158583868,0.3206894848619548,0.3214604351108366,0.3225922076060074,0.3238340507923379,0.3249365280863218,0.3253759596172048,0.3254780500942634,0.32615533510767,0.327479095127002,0.3269626916914626,0.3288306769764873,0.3310249796841324,0.3345171588188348,0.338092177745134,0.3417519181585677,0.3429593662151802,0.3427335239125396,0.3453258061429528,0.3423728813559322,0.3457289559670141,0.3479771148344912,0.3517951572502087,0.3514890282131661,0.0,2.10570516779022,57.17661813441046,188.3535087635299,264.74167627026134,fqhc4_implementation,85 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-100000,95749,44338,420.0148304420934,6130,62.851831350719074,4797,49.5984292264149,1858,19.04980730869252,77.3358889068281,79.69530742381983,66.19428613524023,68.06580803262689,77.09489982227058,79.45641082932194,66.08937158315635,67.96438951196684,0.2409890845575262,238.8965944978878,0.1049145520838834,101.4185206600473,122.67904,91.3193570055442,128125.4321193955,95373.46291401912,247.74594,175.4748523041948,258340.964396495,182861.2333331887,260.34866,143.35278481042587,269658.8058360923,147821.41999349065,3183.82207,1689.3013378998903,3293024.418009588,1732150.9549968028,892.48226,462.499091761943,922951.1953127448,473910.7218341132,1630.94186,804.2678357005778,1673655.505540528,812761.2664142629,0.38094,100000,0,557632,5823.8832781543415,0,0.0,0,0.0,29411,306.61416829418584,0,0.0,32986,341.497039133568,1325408,0,58119,0,0,0,0,0,55,0.5744185317862328,0,0.0,1,0.0104439733052042,0,0.0,0.0613,0.1609177298262193,0.3030995106035889,0.01858,0.3273549594510293,0.6726450405489707,24.52812000062906,4.4078223077199885,0.3304148426099645,0.2301438398999374,0.2143006045445069,0.225140712945591,11.42361218852522,5.941330747121498,19.999233266422568,12312.38060268162,54.5442083702859,13.29207717114741,17.82654607696613,11.999918677089152,11.42566644508319,0.5751511361267458,0.7952898550724637,0.7085173501577287,0.5787037037037037,0.1293774319066148,0.7225656877897991,0.9183673469387756,0.8571428571428571,0.73828125,0.1781376518218623,0.5206965458178704,0.7275280898876404,0.6585160202360877,0.529126213592233,0.1139564660691421,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022897437715929,0.0044821222138844,0.0068315856790474,0.0089128733599601,0.0109890109890109,0.0130404661966665,0.0152088539807211,0.0174945871971894,0.0196425284770649,0.0216770256294733,0.0238043979701676,0.0257705497032793,0.0278643182495861,0.0299042323138708,0.032149266662541,0.0341037058464971,0.0362330093067072,0.0381200340227786,0.0403987899075797,0.0423568139675396,0.0568141482053744,0.0705772792432692,0.083794781441396,0.0966158180805096,0.1087094053142134,0.1247024722571909,0.1390580894369336,0.1533352492256602,0.1670618391541172,0.1797208344947361,0.1949523009669014,0.2045695493195439,0.2142942603247805,0.2229050034989503,0.2309917719012628,0.2403250988251708,0.2504603229514234,0.259343454236487,0.266398701048018,0.2729679245499238,0.2799073806078148,0.2859935158417116,0.292567055255426,0.2981499022793492,0.3036252674576931,0.3084568525414951,0.3129301929767477,0.317697336623337,0.3219443329145566,0.326495591108295,0.3250127904784985,0.3233967660323397,0.3220553671203186,0.3219984116670276,0.3209192465387129,0.3191811862694062,0.3183018420428492,0.3181303998557306,0.3187973258748891,0.3205157889112508,0.3216241984632929,0.3233537654965804,0.3250674305308716,0.3253135970306106,0.3272021599730003,0.3284639105210892,0.3294945982155582,0.3325792566060263,0.3353093868387821,0.338883602917856,0.341034655951783,0.3419694689314126,0.3440261237034191,0.3463565891472868,0.345249474287899,0.3520076941572493,0.356072432094911,0.3581596864039612,0.3588879528222409,0.3567877629063097,0.0,1.83098339766383,57.15610558560863,180.4834404084974,261.68495391677567,fqhc4_implementation,87 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-100000,95742,44524,419.9828706314888,6275,64.02623717908546,4953,51.04342921601805,1915,19.594326418917507,77.34669986567081,79.7119912887041,66.1957183440503,68.07334860669536,77.09925747444967,79.46815161835738,66.08693360723046,67.96956065552592,0.2474423912211421,243.83967034671628,0.1087847368198424,103.78795116943706,123.00552,91.5739725731679,128476.0293288212,95646.60501469352,248.3354,175.834047144586,258865.49267823945,183139.7371525412,264.89883,146.08376217111146,273321.8545674835,149822.9137273826,3305.17225,1754.353965704653,3410231.455369639,1790442.5599054256,918.42821,472.9642654874296,947319.1076016796,482043.7378448641,1684.08783,828.8407225334715,1724981.6172630612,834155.896930875,0.38363,100000,0,559116,5839.819514946418,0,0.0,0,0.0,29549,307.9108437258465,0,0.0,33449,344.8956570783982,1322855,0,58029,0,0,0,0,0,69,0.7102421090012743,0,0.0,1,0.0104447368970775,0,0.0,0.06275,0.1635690639418189,0.3051792828685259,0.01915,0.3220210013696545,0.6779789986303455,24.411300885154013,4.371207908879344,0.3216232586311326,0.2394508378760347,0.2208762366242681,0.2180496668685645,11.464385009455176,6.015327557750815,20.501527850409733,12458.515292236843,56.38776852579978,14.227481371483384,18.048102644973927,12.051976369880936,12.060208139461528,0.5663234403391884,0.7841483979763912,0.7074701820464532,0.5740740740740741,0.1170018281535649,0.7397260273972602,0.9290465631929048,0.8811188811188811,0.6959706959706959,0.1666666666666666,0.4988782950084128,0.6952380952380952,0.6434707903780069,0.5328376703841388,0.1034883720930232,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024821437617141,0.0048270966433424,0.0070039384465467,0.0092476855380425,0.011811504262722,0.0141173594630106,0.0165221825599184,0.0190579295694092,0.0214461034976477,0.0234051706477649,0.0256407626588445,0.0278642222564576,0.0299847761685319,0.0323119088342572,0.0344023203245151,0.0363168341396849,0.0383089781165529,0.0402644168404885,0.0424231081165387,0.0441640707208568,0.0579061100497948,0.0723666998063942,0.0850383296454376,0.0973309926520829,0.1087302507457023,0.1249656426411823,0.1397205377210466,0.1538527014661758,0.1667681201208898,0.1799894918561885,0.195512199323815,0.2057522363197802,0.2145412240548856,0.2242925250404583,0.2329361018497122,0.2425695959942838,0.2510819613617097,0.2604094027668429,0.2684194401261815,0.275709981555945,0.2837069873493906,0.2897585637880792,0.2961433321893897,0.3019419452996777,0.3075633722413186,0.3123837674733666,0.3160689240633139,0.3197535265060854,0.3237131304753512,0.3281885934774565,0.3279380053908355,0.3268545647120318,0.3263697280252266,0.326568638779755,0.3261931995424769,0.3233278257144605,0.3218961482512175,0.3236248606831443,0.3244406490179334,0.3250709352749076,0.3253294344786219,0.3274796041325089,0.3278928953047413,0.32871260564325,0.3306893567926161,0.3314596507663882,0.3320523768858525,0.3340654513507577,0.3355205445805116,0.3375366801490999,0.3410697186630796,0.3446799400556626,0.3458286002776726,0.3487571701720841,0.3489031770045386,0.3535990481856038,0.3544187471281972,0.3527037933817595,0.3533772652388797,0.3549618320610687,0.0,2.687481705295998,60.4297600847765,183.0368864471813,265.73669800792584,fqhc4_implementation,90 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-100000,95707,48028,459.36033936911616,4607,46.96626161095845,3676,37.79242897593698,1392,14.126448431149235,77.3909887370755,79.78544361295366,66.20644897085415,68.1074968868725,77.20832843232463,79.60854591325366,66.1254581815723,68.03183489022666,0.1826603047508683,176.89769969999247,0.0809907892818557,75.6619966458345,203.1315,151.07114491177683,212242.6363797841,157847.08695474398,364.82314,266.1578475579191,380726.6344154555,277635.9389155642,348.4574,193.76156736236211,361225.6679239763,200131.97147871304,2414.00871,1331.140315728948,2479740.854900896,1348314.671579872,658.75865,351.84800117092146,676182.3377600384,355518.74320612726,1215.68097,605.4694235034573,1234448.159486767,601157.5717623843,0.37876,100000,0,923325,9647.39256271746,0,0.0,0,0.0,43910,458.158755367946,0,0.0,43623,451.9523127879884,815988,0,35779,0,0,0,0,0,77,0.804538852957464,0,0.0,1,0.0104485565319151,0,0.0,0.04607,0.1216337522441651,0.3021489038419796,0.01392,0.3647916666666667,0.6352083333333334,22.63409257138304,4.032842067858146,0.2976060935799782,0.294341675734494,0.2026659412404788,0.2053862894450489,11.57399805841836,6.24618642649236,14.873897756617216,11265.200638825178,42.60360964382709,13.536363281758211,12.51730437919919,8.515470439013066,8.034471543856622,0.6011969532100109,0.8262476894639557,0.7111517367458866,0.5854304635761589,0.1288590604026845,0.7691056910569106,0.9376218323586744,0.8374233128834356,0.7377777777777778,0.1566265060240964,0.5167620605069502,0.7258347978910369,0.6575520833333334,0.5207547169811321,0.1208981001727115,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0019663092173278,0.004128919683889,0.0063662578182113,0.008691851008458,0.0108596087691086,0.0131047976195328,0.0152731724736009,0.0171001287106462,0.0192524091085786,0.0212449934953853,0.0233424308961441,0.0254428870894816,0.0276820169796758,0.0296964386950471,0.0317101377444602,0.0336608066184074,0.035400888907307,0.0375764244267519,0.0397466036990034,0.0416436471287252,0.0565424904178546,0.0704641085222634,0.0833298363407469,0.0963036963036963,0.1085948043184885,0.1235173478233291,0.138073272891151,0.1514758145176735,0.1646895520794405,0.1774114014964732,0.19259418729817,0.2005901937046005,0.2081363888255044,0.2143075645675829,0.2191285422208543,0.2259146510211988,0.2337136547662863,0.240672250014052,0.2465432042796264,0.2524791545139485,0.2578087985485977,0.2630522088353413,0.266678472345198,0.2711627239457507,0.2752957432366915,0.278154163951358,0.2822103502508924,0.2851738539855026,0.2885532283281434,0.2908282115736414,0.2887796755827693,0.2845168194040498,0.2813807825183271,0.2786098337970104,0.2755445002146908,0.270969021216882,0.2669020077536483,0.2685368123703933,0.268703379606817,0.2688143414980475,0.2692207259297944,0.2696600460620854,0.2717724288840262,0.2721459970694019,0.2729505460441604,0.2732379847957737,0.2746393723814076,0.2787685840571199,0.2841975054118132,0.289290573372206,0.29150682487287,0.2949670181270451,0.3006868637311419,0.3072932107915802,0.3116645303058048,0.3175528873642081,0.3236293778631594,0.3295543393275997,0.3288144603934078,0.3276239067055393,0.0,2.3428449723657847,53.4360444060964,129.85287578924618,176.46132928776626,fqhc3_implementation,38 -100000,95781,48123,459.0680823962999,4694,47.74433342729769,3836,39.47547008279304,1481,15.128261346196007,77.44562150151836,79.77677825484383,66.25752162197742,68.10235652581221,77.25003596942086,79.58354479869892,66.16987887537843,68.01820308111284,0.1955855320974961,193.2334561449096,0.0876427465989877,84.1534446993677,202.60196,150.76112702314026,211526.2525970704,157401.91376488056,368.16596,268.6740603522465,383968.85603616585,280094.49718863505,355.54653,198.1058023662497,368406.50024535134,204531.061911169,2504.1297,1380.5640780145895,2578255.9067038344,1405349.968648342,661.38941,357.94599934166894,680400.8519434961,363629.5958072483,1285.68543,646.9430348295538,1314038.3687787766,649453.0422591207,0.3801,100000,0,920918,9614.8296635032,0,0.0,0,0.0,44151,460.3835833829256,0,0.0,44486,460.6550359674674,814982,0,35756,0,0,0,0,0,97,1.012726950021403,0,0.0,0,0.0,0,0.0,0.04694,0.1234938174164693,0.3155091606305922,0.01481,0.3716741711011052,0.6283258288988948,22.40139474899516,3.948995558010636,0.3052659019812304,0.2935349322210636,0.1962982273201251,0.2049009384775808,11.384249916622164,6.301352465261855,15.951591946469636,11291.82724366464,44.33930040555407,13.92732062926587,13.385042891071237,8.758525472295071,8.26841141292189,0.6003649635036497,0.8161634103019538,0.7096498719043552,0.583969465648855,0.1248339973439575,0.7764887857695282,0.920388349514563,0.8710526315789474,0.7636363636363637,0.1741573033707865,0.5108139992135273,0.7283142389525368,0.6321112515802781,0.5141342756183745,0.1095652173913043,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022476688029644,0.0045805085175163,0.0067146769449234,0.0089661054812046,0.0112622227643268,0.0134840836929088,0.0158155934414201,0.0179150768226244,0.0200118497936501,0.0219566596410812,0.0241188524590163,0.0263228110504494,0.0285206273510246,0.0305216997447088,0.0322743630195605,0.0342811696293006,0.0363429399285973,0.0383650276850334,0.0402514416333316,0.0423755283926451,0.0569138778449112,0.0710401372069189,0.0839963520865436,0.0974379453120074,0.1095343447113358,0.1250766077051501,0.1393387921994004,0.1530040706139931,0.1663537644272822,0.1791988003427592,0.1941812315138478,0.200467006832137,0.2077840211283678,0.2154423100051387,0.2210961828365188,0.2285730113006869,0.2359833943397911,0.2425056783682281,0.2481650803734501,0.2536840056333512,0.2590224955494417,0.2637904252461429,0.2688086941113933,0.2738792588164973,0.2769924046952793,0.279398751290497,0.2829948446530439,0.2866373018190127,0.2887333040535303,0.2902432286665176,0.287227765261238,0.2824960947134753,0.2790172940549934,0.275572793219852,0.2726533869251684,0.2686530786338847,0.2654278251565597,0.266066271841809,0.2652790756945034,0.2651826888967719,0.2649571059046839,0.2653153418576788,0.2661226528997876,0.266977466977467,0.2689235450741727,0.270548827621747,0.2721780425436255,0.2776194311915236,0.2814576411960133,0.2841912051862845,0.2884020964924069,0.291527021365731,0.2964833520389076,0.2976002407282028,0.2995298239144464,0.304195395582564,0.3085551899491475,0.3156446540880503,0.3247773703509691,0.3246323529411765,0.0,2.26585658875372,56.35402509880412,132.54186391006223,184.83575485834845,fqhc3_implementation,39 -100000,95706,48660,463.8371679936472,4594,46.966752345725446,3677,37.84506718492048,1396,14.220634025035002,77.31966845828218,79.69829506646285,66.17605969217594,68.06067535754809,77.13636472218771,79.51876833980545,66.09410923231258,67.98346621061577,0.1833037360944729,179.5267266574001,0.0819504598633642,77.20914693231862,201.48018,150.0209131225512,210519.67483752323,156751.60713283508,364.65413,266.5746919191833,380583.3281090005,278103.4020011109,356.71407,198.06316538598463,370183.1860071469,204804.2643098432,2392.44529,1306.4556677566936,2463355.4322613003,1328641.1800270565,635.55106,335.28284858501183,653267.3186634067,339551.7490220176,1210.19714,607.6725305350052,1233305.821996531,606145.2788071481,0.38322,100000,0,915819,9569.07612897833,0,0.0,0,0.0,43721,456.22009069441833,0,0.0,44622,462.79230142310826,815601,0,35736,0,0,0,0,0,80,0.8358932564311538,0,0.0,0,0.0,0,0.0,0.04594,0.119878920724388,0.30387461906835,0.01396,0.3622704507512521,0.6377295492487479,22.8455347279271,4.005017076221711,0.299972803916236,0.3048680989937449,0.1952678814250747,0.1998912156649442,11.151147161185316,6.130705139855585,15.032985045472207,11376.475802923607,42.693315846730734,14.037202610986071,12.577563580517449,8.171115232400021,7.907434422827194,0.6004895295077509,0.8198037466547725,0.7017225747960109,0.5836734693877551,0.1197771587743732,0.7649536647009267,0.9064885496183206,0.8589743589743589,0.7593582887700535,0.1402439024390244,0.5220883534136547,0.7437185929648241,0.6396965865992414,0.5237226277372263,0.1137184115523465,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0023193396465285,0.0046427231903009,0.0070939260161363,0.0094864711140001,0.0115823833880759,0.0136958403339952,0.0157550171316691,0.0178161212925621,0.0201206420611389,0.0220652229560231,0.0241786637135474,0.0261795698703859,0.0284012590779105,0.0305322273172239,0.0324667953229651,0.0345415822339853,0.0367039956904142,0.0390715827935558,0.0413217123601114,0.04351950299164,0.0585095827458352,0.0724601280924274,0.0861296717820691,0.0988032138650513,0.1109119095578077,0.1263710112430854,0.1419780592866085,0.1566103427348516,0.169519779444765,0.1819449809021072,0.1965881047061739,0.2027960668803604,0.2093610536627843,0.2165112103695918,0.2219812162117525,0.2296401410168289,0.2366326131859543,0.2442596010985547,0.2497615370639535,0.2552925525814812,0.2605255230901128,0.2648867029685579,0.2693551635489106,0.2732431200364692,0.2773887673231218,0.2802915387176736,0.2836471605216672,0.2870197141511715,0.2892442236539108,0.2912393556721415,0.287923069670972,0.2844577202086803,0.2805455365193868,0.2779991913590943,0.2758098518364559,0.2708183473882367,0.2680448216458837,0.2687448862706594,0.2680780816555762,0.267513095977981,0.268331780055918,0.2681026851578637,0.2703384179378177,0.2701566254338347,0.2714111369020555,0.2723927969944293,0.2732936845086378,0.2782193958664546,0.2834850907068881,0.2871964159396368,0.2878529041539291,0.2930899199665219,0.2956852001743353,0.3015849056603774,0.3037691949744067,0.3055294117647059,0.3104905660377358,0.3216050602885946,0.3225719666397632,0.3258003766478343,0.0,2.19848754962606,51.78643290691434,134.06953337160024,179.85374132795582,fqhc3_implementation,40 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-100000,95667,48183,460.1377695548099,4722,48.11481493095843,3812,39.25073431799889,1342,13.651520377977777,77.27980026021488,79.67846502631515,66.14986521675318,68.05013959195313,77.10191159498467,79.50313066258778,66.07045413788317,67.97442211749745,0.1778886652302134,175.334363727373,0.0794110788700095,75.71747445567212,201.8555,150.25617562529447,210998.045302978,157061.65723320944,363.96996,265.29866572843923,380028.2333511033,276887.8670058006,352.28171,195.88952408948165,365543.4371308811,202492.8956849626,2473.5538,1356.3343170220294,2548001.23344518,1380180.058977526,668.10699,359.12314013883093,682054.3029466796,359075.79430611373,1171.32632,592.2220501710523,1192434.9462196997,589658.1930652563,0.38056,100000,0,917525,9590.820241044456,0,0.0,0,0.0,43713,456.3224518381469,0,0.0,44086,457.2527621854976,814910,0,35791,0,0,0,0,0,91,0.9407632726018376,0,0.0,0,0.0,0,0.0,0.04722,0.1240803027117931,0.2842016094875053,0.01342,0.3691004437273094,0.6308995562726906,22.949847596900707,3.9367920856841216,0.3132214060860441,0.2990556138509968,0.1946484784889821,0.1930745015739769,11.606541324672584,6.479690871338078,14.536718246046169,11374.571594981458,44.06460591523993,14.103478781472212,13.683293596410444,8.18620476510039,8.091628772256875,0.6025708289611752,0.8087719298245614,0.7102177554438861,0.6005434782608695,0.11455525606469,0.7662129703763011,0.904296875,0.8693333333333333,0.7422680412371134,0.1428571428571428,0.5228248146703083,0.7308917197452229,0.6373626373626373,0.5498154981549815,0.1062717770034843,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024213075060532,0.0044617958728388,0.0067501725608023,0.0090242068250645,0.0110386505376891,0.0134468848050201,0.015555351550945,0.0179271880362834,0.0195849824604465,0.021886073615862,0.0242956915913729,0.0264801347631373,0.0282487038103859,0.0304142146000597,0.0325891658577889,0.0344417438072089,0.0363984872817696,0.0384902917661717,0.0405905978815058,0.0426940520252306,0.0580983524347817,0.0722745217127239,0.0858408287066676,0.0985035044516006,0.1112177931587499,0.1266797875267178,0.1416350011675547,0.1558130371348547,0.1692779582763338,0.1821087632736243,0.1966753929521778,0.2033465376539602,0.2100603621730382,0.216903073286052,0.2223984841474431,0.2289647064043124,0.2362267186574751,0.2431756475107871,0.2488482407944579,0.254847486424742,0.2601052851278959,0.264806605211925,0.2688714521432556,0.2726277811184606,0.2753545494419806,0.2788796834425621,0.2832160804020101,0.2872845653006511,0.290683923953582,0.2922288574341591,0.2890540686380315,0.2853008860532734,0.2823680388092116,0.2790815294355654,0.2758149956226908,0.2710766828431898,0.2680430311659547,0.2677778324073618,0.2671141854363308,0.267927950354736,0.2685356163617033,0.2697455045691264,0.2692988115803276,0.2697979730778613,0.2711581557240261,0.273020709600785,0.2757714479484571,0.2794864603782992,0.2852721265866805,0.2907542579075425,0.2951693002257336,0.3002365308804205,0.3030586766541823,0.3085869647307605,0.3134091756807161,0.3167114329090272,0.3217755193543566,0.3292925278219396,0.3265642151481888,0.3332038834951456,0.0,2.317529999037983,54.45295202039977,134.034693441986,187.04091138772807,fqhc3_implementation,42 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-100000,95667,48592,464.2562221037557,4687,47.8743976501824,3781,38.958052410967206,1437,14.665454127337537,77.38921473078054,79.79233960386028,66.20625164509725,68.10985656850859,77.19943588547791,79.60492328688187,66.12226129828598,68.02903361571971,0.1897788453026265,187.416316978414,0.0839903468112766,80.82295278887841,202.91282,150.9212872256305,212103.25399563063,157756.89341740674,366.74176,267.3345775751752,382945.0176131791,279035.4328819502,355.77133,197.7752845474239,368739.6489907701,204148.26200264148,2475.37137,1365.089656278892,2554680.7676628307,1394111.5915403364,669.97908,361.59846977395154,689254.5391827903,366906.59242366935,1247.94817,622.3363976789699,1275268.6924435804,626233.6987342739,0.38311,100000,0,922331,9641.056999801394,0,0.0,0,0.0,44040,459.78237009627145,0,0.0,44510,461.1203445284163,814599,0,35675,0,0,0,0,0,87,0.8989515715973115,0,0.0,1,0.0104529252511315,0,0.0,0.04687,0.1223408420558064,0.306592703221677,0.01437,0.3635245901639344,0.6364754098360655,22.742704533935743,3.929277995077261,0.2954244908754297,0.3054747421317111,0.1957154192012695,0.2033853477915895,11.372371321565003,6.3831201366038925,15.4171895361697,11450.26957902018,43.833502441617256,14.391394843083296,12.662538190096711,8.599470801339193,8.180098607098062,0.6061888389314996,0.8216450216450216,0.7099373321396598,0.599479843953186,0.1202702702702702,0.7699604743083004,0.9439252336448598,0.8647058823529412,0.746268656716418,0.1322751322751322,0.5238473767885533,0.7161290322580646,0.6422136422136422,0.5475352112676056,0.1161524500907441,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022392218450782,0.0045938545786431,0.0070143738833847,0.0091951920829904,0.0113437512717209,0.0133962225708522,0.0156366344005956,0.0181287087252709,0.0202299132711503,0.0223526639827079,0.0243234370832392,0.0261981815379873,0.0281319133611154,0.0304766812677145,0.032244076196376,0.0344014397716224,0.0364514257294429,0.038690723361847,0.0405596587953812,0.042841060707138,0.0566816424616027,0.0709124798425097,0.0847964570193205,0.0983751473312005,0.1106890366149625,0.1269335759781619,0.1417398870919818,0.1561175593653498,0.1696268273916388,0.182671472399219,0.1970721933774263,0.2037706443862421,0.2106654482556052,0.2187783770773388,0.2242725180838297,0.2313573407202216,0.2384587057681363,0.2455646930441337,0.2509932572025337,0.2571415481181133,0.2631834638474084,0.267175304949292,0.2724319215547285,0.276550948632677,0.280292660472666,0.28396897776576,0.2873547436873572,0.2899552354261511,0.2920086727582469,0.2937304569461597,0.2901612751866797,0.2855773181755924,0.2829926628414304,0.2809492988133765,0.2776487298229002,0.2730402986211624,0.2685904899770274,0.2687822564839616,0.2685925850444116,0.2693310165073849,0.2701784354865663,0.2720859136160539,0.2729050105035462,0.2728483583812462,0.274109615200993,0.2755197021408626,0.2768171945956618,0.2814034433463857,0.2872318339100346,0.2911709455228553,0.2976510668818361,0.3007601572739187,0.3051944012441679,0.3111608809257185,0.3133070794028757,0.3161739130434782,0.3213055846683635,0.3215484890381196,0.3312269615587151,0.3381871132144157,0.0,2.238788436553042,55.21371410502737,132.64597481004654,182.6752265619457,fqhc3_implementation,44 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-100000,95625,48004,458.5098039215686,4726,48.25098039215686,3818,39.3202614379085,1462,14.797385620915032,77.27391128214566,79.69259821501299,66.1437727881372,68.06060662287514,77.0685257869072,79.49482544170027,66.05192257697303,67.97573394074124,0.2053854952384597,197.77277331272103,0.0918502111641714,84.87268213390564,200.60458,149.26556714234766,209782.56732026144,156094.7107370956,364.22443,266.23503335191026,380419.7437908497,277950.75227660185,352.41119,195.95096911696248,366207.3620915033,202903.6443921389,2487.41114,1379.4791516770547,2558040.0,1399981.730337089,683.25443,366.9337453064609,700371.9633986929,369718.735095674,1266.83217,642.8862207604806,1283117.2601307188,634657.1981033335,0.37868,100000,0,911839,9535.571241830065,0,0.0,0,0.0,43631,455.6130718954248,0,0.0,44160,458.6875816993464,821733,0,36006,0,0,0,0,0,101,1.0562091503267974,0,0.0,3,0.0313725490196078,0,0.0,0.04726,0.1248019435935354,0.3093525179856115,0.01462,0.3588449111470113,0.6411550888529887,22.651678333356784,3.941325613947253,0.3103719224724987,0.2881089575694081,0.1956521739130435,0.2058669460450497,11.69737781570174,6.715045733670869,15.896574827133405,11308.08247963445,44.542856523730535,13.725687411307735,13.650066791753382,8.948262141439226,8.218840179230186,0.609219486642221,0.8209090909090909,0.7232067510548523,0.5916030534351145,0.1352074966532797,0.7726550079491256,0.9126984126984128,0.882183908045977,0.7678571428571429,0.1813186813186813,0.52890625,0.7432885906040269,0.6571087216248507,0.5213523131672598,0.1203539823008849,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0022895581963144,0.0048271945481096,0.0069134248355396,0.0091356218116781,0.011077880859375,0.0131089766442242,0.0155714635340186,0.0179510481655825,0.0201268152996522,0.0223107732967291,0.0243672217263278,0.0263677093180977,0.0283799641776295,0.0305020778122647,0.0325789424755451,0.0346701164294954,0.0364971071895153,0.0386800585809694,0.0406111446472804,0.0426102285410299,0.0575009407534389,0.0706711929758387,0.0841154855643044,0.0974421052631579,0.1092593960758652,0.1240898315129963,0.1389723605551249,0.1524863879979968,0.1660231247259153,0.1790132737660552,0.1937150747588944,0.2004335573379579,0.2073621236392167,0.2145675332076629,0.2197550192390381,0.2274502840909091,0.2347509167337447,0.2416624429802331,0.2472102906752119,0.2526204729466272,0.2589012517385257,0.2630906768837803,0.2677307277276446,0.2729608683644921,0.2763452369368492,0.2803741777838111,0.2844055093932899,0.2876799592304752,0.2895228215767635,0.2923326904277524,0.2887038309684548,0.2840213856583806,0.2803361439327712,0.2777191740242475,0.2752259483886312,0.2701313010742815,0.266809015421115,0.2672582047202768,0.266036254395248,0.265975296301585,0.267947781461295,0.2694083751036034,0.2704636759290257,0.2719241494701617,0.2727773519831385,0.2725007138963163,0.2738998266996221,0.2777324632952692,0.2832819506726457,0.2887393627547991,0.2919141989025441,0.2957709344020249,0.298292789694203,0.2998330044026112,0.3063307735530998,0.3090844570617459,0.313588850174216,0.3174920127795527,0.3223231489127443,0.3266563944530046,0.0,2.32675319533278,54.82508900953039,139.149387656109,184.9646209028332,fqhc3_implementation,48 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-100000,95706,44853,424.4770442814453,5832,59.67232984347898,4633,47.76085093933504,1894,19.34048022067582,77.3565045794107,79.7291239956336,66.19734416547256,68.07650512599793,77.11558277518172,79.49161627295983,66.09226481649907,67.97583123986148,0.2409218042289751,237.50772267376877,0.10507934897349,100.67388613644825,138.55798,103.03568264198822,144774.60138340332,107658.54036527305,269.36021,192.31708464839213,280949.7941612856,200453.64374028947,275.89965,152.60674600219556,285465.80151714623,157020.86492615417,3118.57506,1666.2833095289516,3215346.9792907443,1698296.396271033,830.13166,434.8141187759293,855660.4810565691,442616.0546076801,1662.76075,811.2039516341442,1699569.692600255,814832.7796326876,0.37986,100000,0,629809,6580.663699245606,0,0.0,0,0.0,32001,333.6781393016112,0,0.0,34830,360.1341608676572,1226874,0,53732,0,0,0,0,0,73,0.7627525964934277,0,0.0,0,0.0,0,0.0,0.05832,0.1535302479861001,0.3247599451303155,0.01894,0.3490473061760841,0.6509526938239159,24.399922872136848,4.3457353329640975,0.3103820418735161,0.2398014245629182,0.2186488236563781,0.2311677099071875,11.399787382048146,6.010955424285873,20.05367454538905,12146.65586295663,52.9597246824432,13.516615040395154,16.375537180729523,11.976164758994496,11.091407702324044,0.5687459529462551,0.8037803780378038,0.7121001390820584,0.5732959850606909,0.102665350444225,0.7331334332833583,0.9202733485193622,0.8771498771498771,0.6966292134831461,0.1402714932126696,0.5022734161867233,0.7276785714285714,0.646944713870029,0.5323383084577115,0.0921717171717171,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0025828015800668,0.0049474836773591,0.0070529018378137,0.0093146566172661,0.0116248321874618,0.0138081321344561,0.0160211303514246,0.0184504482427658,0.0206137077066227,0.0227721859865046,0.0248866922335473,0.0270503419804054,0.0289843147338647,0.0310011230051204,0.0330591307399341,0.0350957014487058,0.0372269882713746,0.0394340758579169,0.0412745291750293,0.0433120090020629,0.0583456039767327,0.071898983341884,0.0849612142714686,0.0979698797082688,0.1106984204028658,0.1263440860215053,0.1406808989479718,0.1550470145995506,0.1685316404287836,0.1809023121077195,0.1958081896551724,0.2040303902681876,0.2126729313495171,0.2208658747347465,0.2284883784944342,0.2376797454460791,0.2464138886406292,0.2554674654834568,0.2628512368534629,0.2700059616619279,0.2768869180627757,0.2830036287018612,0.2884250923907893,0.2934441167302112,0.2979751970751497,0.301721906546203,0.3063006706035432,0.3113633186329957,0.3153389622312158,0.3190174347350527,0.3178474902176982,0.315435319967042,0.3135825746809438,0.3134175535750338,0.3126630305904672,0.3104553711817058,0.309015449194401,0.3096936771828773,0.3094121459146955,0.3091664289788933,0.3101218509381774,0.3112881910885816,0.3120784280866395,0.3129595280130511,0.3130368024566959,0.3134083450539147,0.3150190438292308,0.3185520646601881,0.3210122860443137,0.3244096975440259,0.326595793219875,0.3297957442269745,0.3316081797525877,0.337306134922454,0.3380903201577316,0.3410936007640878,0.3389025137952176,0.340867440439829,0.3376196990424077,0.3420560747663551,0.0,2.4000878469191287,58.39042656966834,173.17482726346202,241.0961370137728,fqhc2_implementation,24 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-100000,95740,45175,428.5147273866722,5820,59.86003760183832,4560,47.15897221641947,1738,17.82953833298517,77.43475768814622,79.82062676315388,66.23356512754759,68.1262428943578,77.2236036080954,79.60915925489618,66.14274395699243,68.0375034117783,0.211154080050818,211.467508257698,0.0908211705551593,88.73948257949849,139.45382,103.69862738714863,145658.88865677878,108312.75056104934,269.75192,192.05159549643335,281401.15939001465,200243.51942389115,274.8079,151.18430322983406,284658.18884478795,155933.91353068055,3077.32015,1607.966463602342,3182157.3845832464,1647518.014252089,840.6065,431.2075335260173,865263.8813453102,437683.9759604468,1529.2602,740.0427390664636,1570050.5640275746,748953.8969570495,0.38067,100000,0,633881,6620.858575308126,0,0.0,0,0.0,32080,334.59369124712765,0,0.0,34585,358.0635053269271,1228301,0,53782,0,0,0,0,0,76,0.7938165865886777,0,0.0,1,0.0104449550866931,0,0.0,0.0582,0.1528883284734809,0.2986254295532646,0.01738,0.3305988515176374,0.6694011484823625,24.51092730665365,4.322901785024718,0.3190789473684211,0.2458333333333333,0.2197368421052631,0.2153508771929824,11.278295421156733,5.910926561381671,18.39062482546677,12119.062336103349,51.22792657187454,13.3817759705849,16.042366171632434,11.008861621290963,10.794922808366245,0.5657894736842105,0.7939339875111507,0.681786941580756,0.5855397148676171,0.122754491017964,0.7471074380165289,0.943127962085308,0.8705882352941177,0.7434782608695653,0.1788990825688073,0.5002985074626866,0.703862660944206,0.6242152466367713,0.5372340425531915,0.1071428571428571,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024427078582215,0.004494724025974,0.0065003656455675,0.0087033440769473,0.0106967655260854,0.0129494350541512,0.01521905441934,0.0175243308381246,0.0197034764826175,0.0217449169720919,0.0238378411630815,0.0258572000698288,0.0278609114189626,0.0300754977391877,0.0321994903380894,0.0340575515772935,0.0361488200635788,0.0383538052950452,0.0404004699179722,0.0424771569373105,0.0570172691014638,0.0706532547599359,0.084079012242072,0.097015003837702,0.1088347866429076,0.1237576654683865,0.138876223398051,0.1529207794417971,0.1656670864192261,0.1776580705962988,0.1930092493009249,0.2027303090242874,0.2110586062679919,0.2197556208301029,0.2279762559085413,0.2369483687535263,0.2461119967892618,0.2543930609860231,0.2627638003103866,0.2697650488766935,0.2765746213520502,0.2824600303419302,0.287968628192105,0.2936449089908871,0.2985516029331556,0.3037971573529231,0.3091525931099858,0.3135198135198135,0.3172500869654843,0.3207425872474416,0.3198025233132199,0.3179829957079198,0.3171637086946168,0.3151899097856691,0.3138473805445632,0.3108410276691866,0.308677478157018,0.3096302581339947,0.3091948951191365,0.3098246610349968,0.3112852781294214,0.312329359077606,0.3139624528577084,0.3152200475418212,0.3164959040863604,0.3156805422606266,0.316638418079096,0.3198818591636872,0.3232477446217904,0.325604205900816,0.3275730165159083,0.3331418424900773,0.3367971794395992,0.339716152286551,0.3456527764945024,0.3519953730480046,0.350401905328967,0.3555992141453831,0.3544,0.348456675343994,0.0,1.783834551074129,53.36045072302652,166.16166865287937,251.6183484018241,fqhc2_implementation,48 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-100000,95656,45127,428.5564941038722,5758,58.85673663962532,4545,46.782219620306094,1786,18.158819101781383,77.22182039149587,79.60755854977698,66.12281660043443,68.0135336804219,76.98567654331349,79.37844012175138,66.01902295397285,67.91661932942753,0.2361438481823796,229.11842802560045,0.1037936464615825,96.91435099436774,138.05748,102.76905773877316,144327.04691812326,107436.08110183696,268.24721,192.1983843662044,279885.01505394327,200382.60471502508,277.8278,153.65934903930574,287286.8717069499,157947.86624875013,3076.7538,1640.1047678315238,3166877.770343732,1665106.3743085568,830.47246,429.6936789191396,854943.1713640544,436004.2349116167,1578.00079,780.7755616423505,1605798.946223969,776662.7934261196,0.38169,100000,0,627534,6560.320314460148,0,0.0,0,0.0,31992,333.6852889520783,0,0.0,35033,362.0473362883666,1218999,0,53585,0,0,0,0,0,68,0.7004265283934097,0,0.0,1,0.0104541272894538,0,0.0,0.05758,0.150855406219707,0.310177144841959,0.01786,0.3432436946717889,0.6567563053282112,23.996730703369547,4.2822251522322645,0.3216721672167216,0.2347634763476347,0.2261826182618261,0.2173817381738173,11.10320272652839,5.743644057176343,19.262684830335857,12173.25809372388,52.236012443925546,13.07158888993421,16.800228460709658,11.105343050745171,11.258852042536509,0.5647964796479648,0.7863167760074976,0.7127222982216143,0.5799595141700404,0.1099221789883268,0.7373202119606359,0.9386363636363636,0.8669950738916257,0.728744939271255,0.1271929824561403,0.494106699751861,0.6794258373205742,0.6534090909090909,0.5303643724696356,0.105,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0024205718221132,0.0049469821381505,0.0072453473504759,0.0092334884098896,0.0112982284865865,0.0134483039459217,0.0154918667699457,0.0177164550761317,0.0198256568526258,0.0220848598972511,0.0242785111092891,0.0264976130588778,0.0285302890054509,0.0304238527951206,0.0323765881248,0.0343518949382141,0.0365669167322916,0.0386703624113696,0.0404755960554237,0.0421250195505969,0.056642216788916,0.0706253141229686,0.0847660432017129,0.0979475844647931,0.1103780257365748,0.1251336558718597,0.1404233624709243,0.1549679879835092,0.1676432222055899,0.1810763217798393,0.1956495950478285,0.204225352112676,0.212361434762724,0.2212315713378168,0.2285033953611429,0.2378086025565563,0.2462640622376448,0.2554993450472018,0.2629443938012762,0.2696602081297073,0.276743888688698,0.2826625932671406,0.288680142687277,0.2950857170374651,0.2996367005583595,0.3041004391118808,0.3086154464801829,0.3136065196842347,0.3176823956206847,0.3211791984100695,0.3197084831931637,0.3179896080924216,0.3163466028897725,0.3144466053235029,0.3132177471140779,0.3113622386223862,0.3098051689860835,0.3112972643173985,0.3120516253046373,0.3128049655568312,0.3143475804933157,0.3150325237214298,0.3158950747655656,0.316938904431008,0.319435348904897,0.3193762633554721,0.3205616850551655,0.3238122350857215,0.3279889573157783,0.3308388026252601,0.3326925717424138,0.333722534762764,0.3367468744110071,0.3372785525819826,0.3404651162790698,0.3428470754052149,0.3456492233448952,0.3462305544475468,0.3412144008597528,0.3394324122479462,0.0,2.8348555628990746,57.48888427566479,166.88849537761214,241.55140015284303,fqhc2_implementation,70 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zjlLa0G-vWLt`U`%>IUqOa#=}p-fp+YVh_uUWt!7`YrMK2lMaKqYDhuiVguuf3D}}p z;tQrkUe11Q5n1Q4=G_Z-y)?IL`f@<{Z|4eZuQZkcPW=Hm81|=g{}j?cUHnT_@8a)~ z1j31e%gNV3G)3b%Hwt)4DXGI=oRJ0mQCZTlOVJ=NV4pC ztmr-|{8=eOk(>nw=bFK)VTav`aJzm2dt5&Iw&8h|dY*qjITGRR{@--vVLS%#J00XD6Kp+ahNCP=X2UmoHtFg8h65(R>Q$=MjhkmN4 z$2k9s+fxBir1UmV6xU80VNjP5YCX%$(bX|_wn{m>k~m2P)pPRQ<$|T8&K!F{%<7(w zmmHKKSbD<$rCtbLCbOHOIyt5wBkbWjXUOvNhG#c9J#Rd~Ifk8izYEac<3Y->g}Hx6=KIl z(X5EJ$*sPzWex7{hgmfex!FTEvrl4Fl%w$TdT{;IxfMpbDFyfAOfMD&9ZcdH6j#UX z3CL#NVf$@l*lm?W_R7Zf8s1$Eve=zr3tDg@KGzX_aLSzL{tdgkVu0b$Ba7|Q0Om!S zbNSV0vOND~&jaGHrF-R4U=0=U4Jg*%uTqGNnpptg#Y*6~2^@cY`~eSxKo*YX8qSVL z7hY2&@~303qsMBh)xQAO^#fOv{RIWi{^0U|qRkzh5&s2GF-&K^i3zKb;i;p)Qs>-3*2 z*M}2-5&46!w7~x!TwHg+^?v(r=&%m>pS}2X;Prm+Z(xJ&uY3M8WUqs-$NAr2s>i>; n|0n9N^IQ+5zj=NDJpU0`8Y(!z;{t*3fv+UcgDV*Pl*#`9a$O=) From b5825b6f84dc40b5433e36d5649064316ff503f8 Mon Sep 17 00:00:00 2001 From: Praveen Zirali Date: Thu, 4 Jan 2024 13:30:30 -0500 Subject: [PATCH 13/20] Update commit SHA in requirements.in --- crcsim/experiment/requirements.in | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/crcsim/experiment/requirements.in b/crcsim/experiment/requirements.in index 53f0b59..7081657 100644 --- a/crcsim/experiment/requirements.in +++ b/crcsim/experiment/requirements.in @@ -1,5 +1,5 @@ # Clone the specific commit of the model that you want to use for the experiment -git+https://github.com/RTIInternational/crcsim.git@f25bb2d2e84729d64df8f30b58ad00d224e1c4c3 +git+https://github.com/RTIInternational/crcsim.git@f805cac52bf0b265aa5498ddbcb5044c81e0e75d7 fire pandas==2.1.1 From bb058cfda8522ed012a776eca4fa473834fd1d23 Mon Sep 17 00:00:00 2001 From: Praveen Zirali Date: Thu, 4 Jan 2024 13:40:43 -0500 Subject: [PATCH 14/20] Update commit SHA in requirements.in --- crcsim/experiment/requirements.in | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/crcsim/experiment/requirements.in b/crcsim/experiment/requirements.in index 7081657..53a40eb 100644 --- a/crcsim/experiment/requirements.in +++ b/crcsim/experiment/requirements.in @@ -1,5 +1,5 @@ # Clone the specific commit of the model that you want to use for the experiment -git+https://github.com/RTIInternational/crcsim.git@f805cac52bf0b265aa5498ddbcb5044c81e0e75d7 +git+https://github.com/RTIInternational/crcsim.git@805cac52bf0b265aa5498ddbcb5044c81e0e75d7 fire pandas==2.1.1 From 863a36edc692923d7d7cad3d0e5eac790ff62812 Mon Sep 17 00:00:00 2001 From: Praveen Zirali Date: Thu, 4 Jan 2024 14:01:25 -0500 Subject: [PATCH 15/20] Update requirements.txt --- crcsim/experiment/requirements.txt | 22 +++++++++++----------- 1 file changed, 11 insertions(+), 11 deletions(-) diff --git a/crcsim/experiment/requirements.txt b/crcsim/experiment/requirements.txt index 8223995..5128bd7 100644 --- a/crcsim/experiment/requirements.txt +++ b/crcsim/experiment/requirements.txt @@ -2,11 +2,11 @@ # This file is autogenerated by pip-compile with Python 3.11 # by the following command: # -# pip-compile +# pip-compile crcsim/experiment/requirements.in # aiobotocore[awscli,boto3]==2.7.0 # via - # -r requirements.in + # -r crcsim/experiment/requirements.in # s3fs aiohttp==3.8.5 # via @@ -36,8 +36,8 @@ colorama==0.4.4 # via awscli contourpy==1.1.1 # via matplotlib -crcsim @ git+https://github.com/RTIInternational/crcsim.git@f25bb2d2e84729d64df8f30b58ad00d224e1c4c3 - # via -r requirements.in +crcsim @ git+https://github.com/RTIInternational/crcsim.git@805cac52bf0b265aa5498ddbcb5044c81e0e75d7 + # via -r crcsim/experiment/requirements.in cycler==0.12.0 # via matplotlib docutils==0.16 @@ -46,7 +46,7 @@ et-xmlfile==1.1.0 # via openpyxl fire==0.5.0 # via - # -r requirements.in + # -r crcsim/experiment/requirements.in # crcsim fonttools==4.43.0 # via matplotlib @@ -56,7 +56,7 @@ frozenlist==1.4.0 # aiosignal fsspec==2023.10.0 # via - # -r requirements.in + # -r crcsim/experiment/requirements.in # s3fs idna==3.4 # via yarl @@ -67,7 +67,7 @@ jmespath==1.0.1 kiwisolver==1.4.5 # via matplotlib matplotlib==3.8.0 - # via -r requirements.in + # via -r crcsim/experiment/requirements.in multidict==6.0.4 # via # aiohttp @@ -78,12 +78,12 @@ numpy==1.26.0 # matplotlib # pandas openpyxl==3.0.9 - # via -r requirements.in + # via -r crcsim/experiment/requirements.in packaging==23.2 # via matplotlib pandas==2.1.1 # via - # -r requirements.in + # -r crcsim/experiment/requirements.in # crcsim pillow==10.0.1 # via matplotlib @@ -103,7 +103,7 @@ pyyaml==6.0.1 rsa==4.7.2 # via awscli s3fs==2023.10.0 - # via -r requirements.in + # via -r crcsim/experiment/requirements.in s3transfer==0.6.2 # via # awscli @@ -119,7 +119,7 @@ tzdata==2023.3 urllib3==1.26.17 # via botocore wheel==0.41.2 - # via -r requirements.in + # via -r crcsim/experiment/requirements.in wrapt==1.15.0 # via aiobotocore yarl==1.9.2 From a3b7f60b7b8275162718aa03364c6bf21c0d61d9 Mon Sep 17 00:00:00 2001 From: "Zirali, Praveen" <144810301+pzirali@users.noreply.github.com> Date: Thu, 4 Jan 2024 14:04:42 -0500 Subject: [PATCH 16/20] Update README.md --- crcsim/experiment/README.md | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/crcsim/experiment/README.md b/crcsim/experiment/README.md index 85a2687..100fddf 100644 --- a/crcsim/experiment/README.md +++ b/crcsim/experiment/README.md @@ -53,7 +53,7 @@ The subdirectories and files in `scenarios/` must be uploaded to AWS S3 for the To upload the files to S3, run ``` -aws s3 cp ./scenarios s3://crcsim-exp-crccp-replication/scenarios --recursive +aws s3 cp ./scenarios s3://crcsim-exp-crccp-sensitivity01/scenarios --recursive ``` *(Another note: this manual step is necessary because `boto3` does not include functionality to upload a directory to S3 recursively. Future experiments could improve this workflow by writing a function to upload the directory recursively in `prepare.py`. Or submit a patch to resolve https://github.com/boto/boto3/issues/358)* @@ -129,4 +129,4 @@ AWS Batch automatically sends log streams from jobs to AWS CloudWatch. Some logg ### ECR -Pushing the Docker image to ECR is the only step of the architecture setup that was NOT completed via the AWS Console. The script `deploy_to_aws.sh` contains all commands necessary to build the `crcsim` Docker image and upload it to ECR. \ No newline at end of file +Pushing the Docker image to ECR is the only step of the architecture setup that was NOT completed via the AWS Console. The script `deploy_to_aws.sh` contains all commands necessary to build the `crcsim` Docker image and upload it to ECR. From a2be8a48e91a5ed55e835585fad7be019bc4cab3 Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Fri, 5 Jan 2024 09:01:52 -0500 Subject: [PATCH 17/20] fix copy bug --- crcsim/experiment/prepare.py | 30 ++++-- .../scenarios/fqhc1_baseline/params.json | 6 +- .../params.json | 2 +- .../params.json | 4 +- .../fqhc1_implementation/params.json | 78 +++++++------- .../params.json | 74 ++++++------- .../params.json | 76 ++++++------- .../params.json | 6 +- .../scenarios/fqhc2_baseline/params.json | 6 +- .../params.json | 2 +- .../params.json | 4 +- .../fqhc2_implementation/params.json | 78 +++++++------- .../params.json | 74 ++++++------- .../params.json | 76 ++++++------- .../params.json | 6 +- .../scenarios/fqhc3_baseline/params.json | 6 +- .../params.json | 2 +- .../params.json | 4 +- .../fqhc3_implementation/params.json | 78 +++++++------- .../params.json | 74 ++++++------- .../params.json | 76 ++++++------- .../params.json | 6 +- .../scenarios/fqhc4_baseline/params.json | 6 +- .../params.json | 2 +- .../params.json | 4 +- .../fqhc4_implementation/params.json | 78 +++++++------- .../params.json | 74 ++++++------- .../params.json | 76 ++++++------- .../params.json | 6 +- .../scenarios/fqhc5_baseline/params.json | 6 +- .../params.json | 2 +- .../params.json | 4 +- .../fqhc5_implementation/params.json | 78 +++++++------- .../params.json | 74 ++++++------- .../params.json | 76 ++++++------- .../params.json | 6 +- .../scenarios/fqhc6_baseline/params.json | 6 +- .../params.json | 2 +- .../params.json | 4 +- .../fqhc6_implementation/params.json | 78 +++++++------- .../params.json | 74 ++++++------- .../params.json | 76 ++++++------- .../params.json | 6 +- .../scenarios/fqhc7_baseline/params.json | 6 +- .../params.json | 2 +- .../params.json | 4 +- .../fqhc7_implementation/params.json | 78 +++++++------- .../params.json | 74 ++++++------- .../params.json | 76 ++++++------- .../params.json | 6 +- .../scenarios/fqhc8_baseline/params.json | 6 +- .../params.json | 2 +- .../params.json | 4 +- .../fqhc8_implementation/params.json | 78 +++++++------- .../params.json | 74 ++++++------- .../params.json | 76 ++++++------- .../params.json | 6 +- crcsim/experiment/scenarios/seeds.txt | 100 ++++++++++++++++++ 58 files changed, 1103 insertions(+), 995 deletions(-) rename crcsim/experiment/scenarios/{fqhc1_implementation_Lower_repeat_compliance => fqhc1_implementation_lower_repeat_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc2_implementation_Lower_repeat_compliance => fqhc2_implementation_lower_repeat_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc3_implementation_Lower_repeat_compliance => fqhc3_implementation_lower_repeat_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc4_implementation_Lower_repeat_compliance => fqhc4_implementation_lower_repeat_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc5_implementation_Lower_repeat_compliance => fqhc5_implementation_lower_repeat_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc6_implementation_Lower_repeat_compliance => fqhc6_implementation_lower_repeat_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc7_implementation_Lower_repeat_compliance => fqhc7_implementation_lower_repeat_compliance}/params.json (99%) rename crcsim/experiment/scenarios/{fqhc8_implementation_Lower_repeat_compliance => fqhc8_implementation_lower_repeat_compliance}/params.json (99%) create mode 100644 crcsim/experiment/scenarios/seeds.txt diff --git a/crcsim/experiment/prepare.py b/crcsim/experiment/prepare.py index 648325e..32af7ff 100644 --- a/crcsim/experiment/prepare.py +++ b/crcsim/experiment/prepare.py @@ -2,7 +2,7 @@ import random from pathlib import Path from typing import Callable, Dict, List, Optional -from copy import copy +from copy import deepcopy import fire @@ -100,16 +100,20 @@ def transform(params): params["tests"][test]["compliance_rate_given_prev_compliant"] = [ rate for _ in params["tests"][test]["compliance_rate_given_prev_compliant"] ] + return transform + # TODO: add transform function to handle lowered diagnostic compliance + def transform_diagnostic_compliance(rate) -> Callable: def transform(params): params["diagnostic_compliance_rate"] = rate return transform + def create_scenarios() -> List: # For each health center, define the initial compliance rate in the baseline # scenario and the implementation scenario. @@ -125,8 +129,8 @@ def create_scenarios() -> List: } low_initial_stage_3_treatment_cost = 67_300 low_initial_stage_4_treatment_cost = 97_931 - diagnostic_compliance_rate= 0.525 - lower_repeat_compliance=0.8 + diagnostic_compliance_rate = 0.525 + lower_repeat_compliance = 0.8 scenarios = [] for fqhc, rates in initial_compliance.items(): @@ -141,17 +145,19 @@ def create_scenarios() -> List: scenarios.append(implementation) # TODO: Sensitivity Analysis 1. Lower repeat compliance (note that the baseline runs stay the same) - + test_name = "FIT" - implementation_lower_repeat_compliance = copy(implementation) + implementation_lower_repeat_compliance = deepcopy(implementation) implementation_lower_repeat_compliance.transform( transform_repeat_compliance(lower_repeat_compliance, test_name) ) - implementation_lower_repeat_compliance.name = f"{fqhc}_implementation_lower_repeat_compliance" + implementation_lower_repeat_compliance.name = ( + f"{fqhc}_implementation_lower_repeat_compliance" + ) scenarios.append(implementation_lower_repeat_compliance) # Sensitivity analysis 2. Lower cost for stage III and stage IV initial phase - baseline_low_cost = copy(baseline) + baseline_low_cost = deepcopy(baseline) baseline_low_cost.transform( transform_treatment_cost("3", "initial", low_initial_stage_3_treatment_cost) ).transform( @@ -160,7 +166,7 @@ def create_scenarios() -> List: baseline_low_cost.name = f"{fqhc}_baseline_low_initial_treat_cost" scenarios.append(baseline_low_cost) - implementation_low_cost = copy(implementation) + implementation_low_cost = deepcopy(implementation) implementation_low_cost.transform( transform_treatment_cost("3", "initial", low_initial_stage_3_treatment_cost) ).transform( @@ -170,18 +176,20 @@ def create_scenarios() -> List: scenarios.append(implementation_low_cost) # TODO: Sensitivity analysis 3. Lower compliance with diagnostic colonoscopy - baseline_lower_compliance = copy(baseline) + baseline_lower_compliance = deepcopy(baseline) baseline_lower_compliance.transform( transform_diagnostic_compliance(diagnostic_compliance_rate) ) baseline_lower_compliance.name = f"{fqhc}_baseline_lower_diagnostic_compliance" scenarios.append(baseline_lower_compliance) - implementation_lower_compliance = copy(implementation) + implementation_lower_compliance = deepcopy(implementation) implementation_lower_compliance.transform( transform_diagnostic_compliance(diagnostic_compliance_rate) ) - implementation_lower_compliance.name = f"{fqhc}_implementation_lower_diagnostic_compliance" + implementation_lower_compliance.name = ( + f"{fqhc}_implementation_lower_diagnostic_compliance" + ) scenarios.append(implementation_lower_compliance) return scenarios diff --git a/crcsim/experiment/scenarios/fqhc1_baseline/params.json b/crcsim/experiment/scenarios/fqhc1_baseline/params.json index 2ea5e5c..a66226f 100644 --- a/crcsim/experiment/scenarios/fqhc1_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc1_baseline/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.522, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json index 2ea5e5c..4eb030b 100644 --- a/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc1_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.522, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc1_baseline_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc1_baseline_lower_diagnostic_compliance/params.json index 2ea5e5c..2080063 100644 --- a/crcsim/experiment/scenarios/fqhc1_baseline_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc1_baseline_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, diff --git a/crcsim/experiment/scenarios/fqhc1_implementation/params.json b/crcsim/experiment/scenarios/fqhc1_implementation/params.json index affe96a..3f10fb6 100644 --- a/crcsim/experiment/scenarios/fqhc1_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc1_implementation/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.593, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json index affe96a..20c819f 100644 --- a/crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc1_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.593, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc1_implementation_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc1_implementation_lower_diagnostic_compliance/params.json index affe96a..db1b4ef 100644 --- a/crcsim/experiment/scenarios/fqhc1_implementation_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc1_implementation_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc1_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc1_implementation_lower_repeat_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc1_implementation_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc1_implementation_lower_repeat_compliance/params.json index affe96a..1ceea57 100644 --- a/crcsim/experiment/scenarios/fqhc1_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc1_implementation_lower_repeat_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.593, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc2_baseline/params.json b/crcsim/experiment/scenarios/fqhc2_baseline/params.json index 9ca2f28..b8ea65b 100644 --- a/crcsim/experiment/scenarios/fqhc2_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc2_baseline/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.154, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json index 9ca2f28..ff67e6a 100644 --- a/crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc2_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.154, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc2_baseline_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc2_baseline_lower_diagnostic_compliance/params.json index 9ca2f28..4f1a780 100644 --- a/crcsim/experiment/scenarios/fqhc2_baseline_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc2_baseline_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, diff --git a/crcsim/experiment/scenarios/fqhc2_implementation/params.json b/crcsim/experiment/scenarios/fqhc2_implementation/params.json index 13dee62..4f87a46 100644 --- a/crcsim/experiment/scenarios/fqhc2_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc2_implementation/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.421, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json index 13dee62..de6a9e4 100644 --- a/crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc2_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.421, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc2_implementation_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc2_implementation_lower_diagnostic_compliance/params.json index 13dee62..7787ded 100644 --- a/crcsim/experiment/scenarios/fqhc2_implementation_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc2_implementation_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc2_implementation_lower_repeat_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc2_implementation_lower_repeat_compliance/params.json index 13dee62..22c05de 100644 --- a/crcsim/experiment/scenarios/fqhc2_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc2_implementation_lower_repeat_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.421, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc3_baseline/params.json b/crcsim/experiment/scenarios/fqhc3_baseline/params.json index 3cfb63e..09c4440 100644 --- a/crcsim/experiment/scenarios/fqhc3_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc3_baseline/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.519, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json index 3cfb63e..05d0e77 100644 --- a/crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc3_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.519, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc3_baseline_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc3_baseline_lower_diagnostic_compliance/params.json index 3cfb63e..4fc812b 100644 --- a/crcsim/experiment/scenarios/fqhc3_baseline_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc3_baseline_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, diff --git a/crcsim/experiment/scenarios/fqhc3_implementation/params.json b/crcsim/experiment/scenarios/fqhc3_implementation/params.json index 8e3df7e..3e104ec 100644 --- a/crcsim/experiment/scenarios/fqhc3_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc3_implementation/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.615, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json index 8e3df7e..e45cf6b 100644 --- a/crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc3_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.615, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc3_implementation_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc3_implementation_lower_diagnostic_compliance/params.json index 8e3df7e..c77fdaa 100644 --- a/crcsim/experiment/scenarios/fqhc3_implementation_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc3_implementation_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc3_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc3_implementation_lower_repeat_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc3_implementation_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc3_implementation_lower_repeat_compliance/params.json index 8e3df7e..22928c8 100644 --- a/crcsim/experiment/scenarios/fqhc3_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc3_implementation_lower_repeat_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.615, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc4_baseline/params.json b/crcsim/experiment/scenarios/fqhc4_baseline/params.json index 4dc3714..1a3667a 100644 --- a/crcsim/experiment/scenarios/fqhc4_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc4_baseline/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.278, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json index 4dc3714..cb19cb9 100644 --- a/crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc4_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.278, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc4_baseline_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc4_baseline_lower_diagnostic_compliance/params.json index 4dc3714..3efb066 100644 --- a/crcsim/experiment/scenarios/fqhc4_baseline_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc4_baseline_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, diff --git a/crcsim/experiment/scenarios/fqhc4_implementation/params.json b/crcsim/experiment/scenarios/fqhc4_implementation/params.json index 1226a6d..33dd49d 100644 --- a/crcsim/experiment/scenarios/fqhc4_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc4_implementation/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.374, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json index 1226a6d..2477fd6 100644 --- a/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc4_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.374, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc4_implementation_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc4_implementation_lower_diagnostic_compliance/params.json index 1226a6d..90c6f70 100644 --- a/crcsim/experiment/scenarios/fqhc4_implementation_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc4_implementation_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc4_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc4_implementation_lower_repeat_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc4_implementation_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc4_implementation_lower_repeat_compliance/params.json index 1226a6d..b7629f5 100644 --- a/crcsim/experiment/scenarios/fqhc4_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc4_implementation_lower_repeat_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.374, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc5_baseline/params.json b/crcsim/experiment/scenarios/fqhc5_baseline/params.json index b635666..0354cba 100644 --- a/crcsim/experiment/scenarios/fqhc5_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc5_baseline/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.383, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json index b635666..0423bd7 100644 --- a/crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc5_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.383, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc5_baseline_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc5_baseline_lower_diagnostic_compliance/params.json index b635666..20390a9 100644 --- a/crcsim/experiment/scenarios/fqhc5_baseline_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc5_baseline_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, diff --git a/crcsim/experiment/scenarios/fqhc5_implementation/params.json b/crcsim/experiment/scenarios/fqhc5_implementation/params.json index 514e1a2..c20c6ef 100644 --- a/crcsim/experiment/scenarios/fqhc5_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc5_implementation/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.572, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json index 514e1a2..d0f464c 100644 --- a/crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc5_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.572, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc5_implementation_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc5_implementation_lower_diagnostic_compliance/params.json index 514e1a2..a40508c 100644 --- a/crcsim/experiment/scenarios/fqhc5_implementation_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc5_implementation_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc5_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc5_implementation_lower_repeat_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc5_implementation_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc5_implementation_lower_repeat_compliance/params.json index 514e1a2..afd9c8a 100644 --- a/crcsim/experiment/scenarios/fqhc5_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc5_implementation_lower_repeat_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.572, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc6_baseline/params.json b/crcsim/experiment/scenarios/fqhc6_baseline/params.json index e8c1faf..acb8998 100644 --- a/crcsim/experiment/scenarios/fqhc6_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc6_baseline/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.211, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc6_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc6_baseline_low_initial_treat_cost/params.json index e8c1faf..04c8f90 100644 --- a/crcsim/experiment/scenarios/fqhc6_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc6_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.211, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc6_baseline_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc6_baseline_lower_diagnostic_compliance/params.json index e8c1faf..dcb186c 100644 --- a/crcsim/experiment/scenarios/fqhc6_baseline_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc6_baseline_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, diff --git a/crcsim/experiment/scenarios/fqhc6_implementation/params.json b/crcsim/experiment/scenarios/fqhc6_implementation/params.json index 79fc678..ff52c16 100644 --- a/crcsim/experiment/scenarios/fqhc6_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc6_implementation/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.392, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json index 79fc678..af76f65 100644 --- a/crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc6_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.392, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc6_implementation_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc6_implementation_lower_diagnostic_compliance/params.json index 79fc678..fdfd33a 100644 --- a/crcsim/experiment/scenarios/fqhc6_implementation_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc6_implementation_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc6_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc6_implementation_lower_repeat_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc6_implementation_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc6_implementation_lower_repeat_compliance/params.json index 79fc678..aa63a53 100644 --- a/crcsim/experiment/scenarios/fqhc6_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc6_implementation_lower_repeat_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.392, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc7_baseline/params.json b/crcsim/experiment/scenarios/fqhc7_baseline/params.json index 7041a9e..a618be5 100644 --- a/crcsim/experiment/scenarios/fqhc7_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc7_baseline/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.257, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json index 7041a9e..b45fc5e 100644 --- a/crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc7_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.257, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc7_baseline_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc7_baseline_lower_diagnostic_compliance/params.json index 7041a9e..83809bd 100644 --- a/crcsim/experiment/scenarios/fqhc7_baseline_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc7_baseline_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, diff --git a/crcsim/experiment/scenarios/fqhc7_implementation/params.json b/crcsim/experiment/scenarios/fqhc7_implementation/params.json index af382f9..817bd2b 100644 --- a/crcsim/experiment/scenarios/fqhc7_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc7_implementation/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.354, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json index af382f9..8c46304 100644 --- a/crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc7_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.354, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc7_implementation_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc7_implementation_lower_diagnostic_compliance/params.json index af382f9..9415446 100644 --- a/crcsim/experiment/scenarios/fqhc7_implementation_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc7_implementation_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc7_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc7_implementation_lower_repeat_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc7_implementation_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc7_implementation_lower_repeat_compliance/params.json index af382f9..8a579e0 100644 --- a/crcsim/experiment/scenarios/fqhc7_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc7_implementation_lower_repeat_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.354, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc8_baseline/params.json b/crcsim/experiment/scenarios/fqhc8_baseline/params.json index 7b29073..5db9689 100644 --- a/crcsim/experiment/scenarios/fqhc8_baseline/params.json +++ b/crcsim/experiment/scenarios/fqhc8_baseline/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.19, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json index 7b29073..bec085c 100644 --- a/crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc8_baseline_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.19, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/fqhc8_baseline_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc8_baseline_lower_diagnostic_compliance/params.json index 7b29073..6c82b97 100644 --- a/crcsim/experiment/scenarios/fqhc8_baseline_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc8_baseline_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, diff --git a/crcsim/experiment/scenarios/fqhc8_implementation/params.json b/crcsim/experiment/scenarios/fqhc8_implementation/params.json index 37c1fed..3ea8359 100644 --- a/crcsim/experiment/scenarios/fqhc8_implementation/params.json +++ b/crcsim/experiment/scenarios/fqhc8_implementation/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.39, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json b/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json index 37c1fed..a5a6747 100644 --- a/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json +++ b/crcsim/experiment/scenarios/fqhc8_implementation_low_initial_treat_cost/params.json @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.39, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc8_implementation_lower_diagnostic_compliance/params.json b/crcsim/experiment/scenarios/fqhc8_implementation_lower_diagnostic_compliance/params.json index 37c1fed..2f68f70 100644 --- a/crcsim/experiment/scenarios/fqhc8_implementation_lower_diagnostic_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc8_implementation_lower_diagnostic_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -106,42 +106,42 @@ "proportion_perforation": 0, "cost_perforation": 0, "compliance_rate_given_prev_compliant": [ - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8, - 0.8 + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0, + 1.0 ], "compliance_rate_given_not_prev_compliant": [ 0.0, diff --git a/crcsim/experiment/scenarios/fqhc8_implementation_Lower_repeat_compliance/params.json b/crcsim/experiment/scenarios/fqhc8_implementation_lower_repeat_compliance/params.json similarity index 99% rename from crcsim/experiment/scenarios/fqhc8_implementation_Lower_repeat_compliance/params.json rename to crcsim/experiment/scenarios/fqhc8_implementation_lower_repeat_compliance/params.json index 37c1fed..cd677bc 100644 --- a/crcsim/experiment/scenarios/fqhc8_implementation_Lower_repeat_compliance/params.json +++ b/crcsim/experiment/scenarios/fqhc8_implementation_lower_repeat_compliance/params.json @@ -27,10 +27,10 @@ "cost_treatment_stage2_initial": 47790, "cost_treatment_stage2_ongoing": 3266, "cost_treatment_stage2_terminal": 77098, - "cost_treatment_stage3_initial": 67300, + "cost_treatment_stage3_initial": 71594, "cost_treatment_stage3_ongoing": 5258, "cost_treatment_stage3_terminal": 79770, - "cost_treatment_stage4_initial": 97931, + "cost_treatment_stage4_initial": 110161, "cost_treatment_stage4_ongoing": 26474, "cost_treatment_stage4_terminal": 99255, "max_ongoing_treatments": 4, @@ -57,7 +57,7 @@ "use_conditional_compliance": true, "initial_compliance_rate": 0.39, "never_compliant_rate": 0.0, - "diagnostic_compliance_rate": 0.525, + "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, "lesion_risk_alpha": 0.47, "lesion_risk_beta": 2.45, diff --git a/crcsim/experiment/scenarios/seeds.txt b/crcsim/experiment/scenarios/seeds.txt new file mode 100644 index 0000000..71149f9 --- /dev/null +++ b/crcsim/experiment/scenarios/seeds.txt @@ -0,0 +1,100 @@ +1001608934 +1865687462 +519221856 +196202418 +1876440239 +481309692 +257361246 +893058778 +1708949663 +859680834 +376198218 +1304159345 +775939283 +107869658 +988217991 +1111981378 +1119296422 +417702499 +72207373 +993413098 +1075012666 +231240803 +728175320 +927495536 +25886288 +2012555507 +148246713 +1297962443 +1763856778 +554891802 +429114708 +1860579156 +799796481 +489401237 +829514650 +1579301123 +2090329059 +975839212 +13289183 +2048157316 +147114907 +1696755228 +18116178 +1616353460 +1961777368 +912178094 +1254009547 +1977383943 +78159626 +1869329937 +518962124 +1230763147 +542633330 +1527010671 +929799851 +40271317 +1493032028 +1144170901 +1879195962 +1997011094 +538722960 +874995561 +889079645 +1080491777 +901894803 +1430866311 +61094092 +890436421 +1864295738 +1679327539 +2098463357 +923285140 +2046685377 +746645880 +666937754 +55104531 +772927900 +160313851 +1961080694 +110389962 +876710936 +1591909998 +562190788 +1708571711 +1797506561 +1390694408 +1314136503 +1680709339 +97192734 +1608349308 +1557554217 +2079799592 +1379281391 +1361121561 +1002686510 +1588416319 +770007412 +293760807 +1614677726 +387482978 From 765bb5774325b8ec1ee02bbf7088208b9b6f72be Mon Sep 17 00:00:00 2001 From: Sandy Preiss Date: Thu, 11 Jan 2024 09:38:47 -0500 Subject: [PATCH 18/20] apply IRR and start lower surv freq sensitivity --- crcsim/experiment/README.md | 2 ++ crcsim/experiment/parameters.json | 2 +- crcsim/experiment/prepare.py | 25 +++++++++++++++++++------ 3 files changed, 22 insertions(+), 7 deletions(-) diff --git a/crcsim/experiment/README.md b/crcsim/experiment/README.md index 100fddf..75de332 100644 --- a/crcsim/experiment/README.md +++ b/crcsim/experiment/README.md @@ -11,6 +11,8 @@ We don't model the intervention explicitly. In other words, we didn't add any co Includes 2 scenarios per health center: one baseline scenario and one intervention scenario. The baseline scenarios are based on real data and the intervention scenarios include a hypothetical increase in screening compliance rates. +All scenarios use an Incidence Rate Ratio (IRR) of 1.19. This is implemented by multiplying the calibrated value of `lesion_risk_alpha` (0.47) by 1.19. + The scenarios are created by `prepare.py`. This script reads a set of base parameters defined in `crcsim/experiment/parameters.json`, modifies them to create the scenarios, and saves them in a directory structure that will eventually be copied to AWS. ## Defining new experiments diff --git a/crcsim/experiment/parameters.json b/crcsim/experiment/parameters.json index 36cb1c0..4a49ac3 100644 --- a/crcsim/experiment/parameters.json +++ b/crcsim/experiment/parameters.json @@ -63,7 +63,7 @@ "diagnostic_compliance_rate": 1.0, "surveillance_compliance_rate": 1.0, - "lesion_risk_alpha": 0.47, + "lesion_risk_alpha": 0.5593, "lesion_risk_beta": 2.45, "lesion_incidence_ages": [ 0, 20, 30, 40, 45, 50, 55, 60, 65, 70, 75, 85, 100 ], "lesion_incidence_rates": [ 0.000, 0.002, 0.002, 0.015, 0.020, 0.025, 0.027, 0.027, 0.027, 0.014, 0.011, 0.011, 0.011 ], diff --git a/crcsim/experiment/prepare.py b/crcsim/experiment/prepare.py index 32af7ff..a241e0e 100644 --- a/crcsim/experiment/prepare.py +++ b/crcsim/experiment/prepare.py @@ -94,7 +94,6 @@ def transform(params): return transform -# TODO: add transform function to handle lowered repeat compliance def transform_repeat_compliance(rate: float, test: str) -> Callable: def transform(params): params["tests"][test]["compliance_rate_given_prev_compliant"] = [ @@ -104,9 +103,6 @@ def transform(params): return transform -# TODO: add transform function to handle lowered diagnostic compliance - - def transform_diagnostic_compliance(rate) -> Callable: def transform(params): params["diagnostic_compliance_rate"] = rate @@ -114,6 +110,20 @@ def transform(params): return transform +def transform_surveillance_frequency(stage: str, frequency: int) -> Callable: + def transform(params): + params[f"surveillance_freq_{stage}"] = frequency + + return transform + + +def transform_surveillance_end_age(age: int) -> Callable: + def transform(params): + params["surveillance_end_age"] = age + + return transform + + def create_scenarios() -> List: # For each health center, define the initial compliance rate in the baseline # scenario and the implementation scenario. @@ -144,7 +154,7 @@ def create_scenarios() -> List: ).transform(transform_initial_compliance(rates[1])) scenarios.append(implementation) - # TODO: Sensitivity Analysis 1. Lower repeat compliance (note that the baseline runs stay the same) + # Sensitivity Analysis 1. Lower repeat compliance (note that the baseline runs stay the same) test_name = "FIT" implementation_lower_repeat_compliance = deepcopy(implementation) @@ -175,7 +185,7 @@ def create_scenarios() -> List: implementation_low_cost.name = f"{fqhc}_implementation_low_initial_treat_cost" scenarios.append(implementation_low_cost) - # TODO: Sensitivity analysis 3. Lower compliance with diagnostic colonoscopy + # Sensitivity analysis 3. Lower compliance with diagnostic colonoscopy baseline_lower_compliance = deepcopy(baseline) baseline_lower_compliance.transform( transform_diagnostic_compliance(diagnostic_compliance_rate) @@ -192,6 +202,9 @@ def create_scenarios() -> List: ) scenarios.append(implementation_lower_compliance) + # TODO: Sensitivity analysis 4. Lower surveillance frequency and end age. + # TODO: add values for lower surveillance frequency by polyp stage and end age + return scenarios From 07c7cfc6148ae349c17a5e270381645158c57544 Mon Sep 17 00:00:00 2001 From: Praveen Zirali Date: Thu, 11 Jan 2024 10:25:44 -0500 Subject: [PATCH 19/20] Updated scenario creation with new surveillance frequency adjustments --- crcsim/experiment/prepare.py | 27 ++++++++++++++++++++++++++- 1 file changed, 26 insertions(+), 1 deletion(-) diff --git a/crcsim/experiment/prepare.py b/crcsim/experiment/prepare.py index a241e0e..4a442b4 100644 --- a/crcsim/experiment/prepare.py +++ b/crcsim/experiment/prepare.py @@ -141,6 +141,9 @@ def create_scenarios() -> List: low_initial_stage_4_treatment_cost = 97_931 diagnostic_compliance_rate = 0.525 lower_repeat_compliance = 0.8 + surveillance_freq_mild = 10 + surveillance_freq_severe = 2 + surveillance_end_age = 80 scenarios = [] for fqhc, rates in initial_compliance.items(): @@ -203,7 +206,29 @@ def create_scenarios() -> List: scenarios.append(implementation_lower_compliance) # TODO: Sensitivity analysis 4. Lower surveillance frequency and end age. - # TODO: add values for lower surveillance frequency by polyp stage and end age + + baseline_lower_surveillance = deepcopy(baseline) + baseline_lower_surveillance.transform( + transform_surveillance_frequency("polyp_mild", surveillance_freq_mild) + ).transform( + transform_surveillance_frequency("polyp_severe", surveillance_freq_severe) + ).transform( + transform_surveillance_end_age(surveillance_end_age) + ) + baseline_lower_surveillance.name = f"{fqhc}_baseline_lower_surveillance" + scenarios.append(baseline_lower_surveillance) + + implementation_lower_surveillance = deepcopy(implementation) + implementation_lower_surveillance.transform( + transform_surveillance_frequency("polyp_mild", surveillance_freq_mild) + ).transform( + transform_surveillance_frequency("polyp_severe", surveillance_freq_severe) + ).transform( + transform_surveillance_end_age(surveillance_end_age) + ) + implementation_lower_surveillance.name = f"{fqhc}_implementation_lower_surveillance" + scenarios.append(implementation_lower_surveillance) + return scenarios From f962f1a69584b9a280eb7a76c0d3a8020a7e75f6 Mon Sep 17 00:00:00 2001 From: Praveen Zirali Date: Thu, 11 Jan 2024 11:08:22 -0500 Subject: [PATCH 20/20] Updated scenario creation with new surveillance frequency adjustments --- crcsim/experiment/prepare.py | 24 ++++++++++++------------ 1 file changed, 12 insertions(+), 12 deletions(-) diff --git a/crcsim/experiment/prepare.py b/crcsim/experiment/prepare.py index 4a442b4..6158205 100644 --- a/crcsim/experiment/prepare.py +++ b/crcsim/experiment/prepare.py @@ -139,11 +139,11 @@ def create_scenarios() -> List: } low_initial_stage_3_treatment_cost = 67_300 low_initial_stage_4_treatment_cost = 97_931 - diagnostic_compliance_rate = 0.525 + low_diagnostic_compliance_rate = 0.525 lower_repeat_compliance = 0.8 - surveillance_freq_mild = 10 - surveillance_freq_severe = 2 - surveillance_end_age = 80 + low_surveillance_freq_mild = 10 + low_surveillance_freq_severe = 2 + low_surveillance_end_age = 80 scenarios = [] for fqhc, rates in initial_compliance.items(): @@ -191,14 +191,14 @@ def create_scenarios() -> List: # Sensitivity analysis 3. Lower compliance with diagnostic colonoscopy baseline_lower_compliance = deepcopy(baseline) baseline_lower_compliance.transform( - transform_diagnostic_compliance(diagnostic_compliance_rate) + transform_diagnostic_compliance(low_diagnostic_compliance_rate) ) baseline_lower_compliance.name = f"{fqhc}_baseline_lower_diagnostic_compliance" scenarios.append(baseline_lower_compliance) implementation_lower_compliance = deepcopy(implementation) implementation_lower_compliance.transform( - transform_diagnostic_compliance(diagnostic_compliance_rate) + transform_diagnostic_compliance(low_diagnostic_compliance_rate) ) implementation_lower_compliance.name = ( f"{fqhc}_implementation_lower_diagnostic_compliance" @@ -209,22 +209,22 @@ def create_scenarios() -> List: baseline_lower_surveillance = deepcopy(baseline) baseline_lower_surveillance.transform( - transform_surveillance_frequency("polyp_mild", surveillance_freq_mild) + transform_surveillance_frequency("polyp_mild", low_surveillance_freq_mild) ).transform( - transform_surveillance_frequency("polyp_severe", surveillance_freq_severe) + transform_surveillance_frequency("polyp_severe", low_surveillance_freq_severe) ).transform( - transform_surveillance_end_age(surveillance_end_age) + transform_surveillance_end_age(low_surveillance_end_age) ) baseline_lower_surveillance.name = f"{fqhc}_baseline_lower_surveillance" scenarios.append(baseline_lower_surveillance) implementation_lower_surveillance = deepcopy(implementation) implementation_lower_surveillance.transform( - transform_surveillance_frequency("polyp_mild", surveillance_freq_mild) + transform_surveillance_frequency("polyp_mild", low_surveillance_freq_mild) ).transform( - transform_surveillance_frequency("polyp_severe", surveillance_freq_severe) + transform_surveillance_frequency("polyp_severe", low_surveillance_freq_severe) ).transform( - transform_surveillance_end_age(surveillance_end_age) + transform_surveillance_end_age(low_surveillance_end_age) ) implementation_lower_surveillance.name = f"{fqhc}_implementation_lower_surveillance" scenarios.append(implementation_lower_surveillance)