diff --git a/test/ml/test_ml.py b/test/ml/test_ml.py
index 3010179d..2bf90f14 100644
--- a/test/ml/test_ml.py
+++ b/test/ml/test_ml.py
@@ -61,6 +61,31 @@ def test_pca(self):
 
         assert coord.equals(expected)
 
+    def test_pca_robustness(self):
+        dataframe = ml.summarize_networks([INPUT_DIR + 'test-data-s1/s1.txt', INPUT_DIR + 'test-data-s2/s2.txt', INPUT_DIR + 'test-data-s3/s3.txt'])
+        expected = pd.read_table(EXPECT_DIR + 'expected-pca-coordinates.tsv')
+        expected = expected.round(5)
+        for _ in range(5):
+            dataframe_shuffled = dataframe.sample(frac=1, axis=1)  # permute the columns
+            ml.pca(dataframe_shuffled, OUT_DIR + 'pca-shuffled-columns.png', OUT_DIR + 'pca-shuffled-columns-variance.txt',
+                OUT_DIR + 'pca-shuffled-columns-coordinates.tsv')
+            coord = pd.read_table(OUT_DIR + 'pca-shuffled-columns-coordinates.tsv')
+            coord = coord.round(5)  # round values to 5 digits to account for numeric differences across machines
+            coord.sort_values(by='algorithm', ignore_index=True, inplace=True)
+
+            assert coord.equals(expected)
+
+        for _ in range(5):
+            dataframe_shuffled = dataframe.sample(frac=1, axis=0)  # permute the rows
+            ml.pca(dataframe_shuffled, OUT_DIR + 'pca-shuffled-rows.png', OUT_DIR + 'pca-shuffled-rows-variance.txt',
+                    OUT_DIR + 'pca-shuffled-rows-coordinates.tsv')
+            coord = pd.read_table(OUT_DIR + 'pca-shuffled-rows-coordinates.tsv')
+            coord = coord.round(5)  # round values to 5 digits to account for numeric differences across machines
+            coord.sort_values(by='algorithm', ignore_index=True, inplace=True)
+
+            assert coord.equals(expected)
+
+
     def test_hac_horizontal(self):
         dataframe = ml.summarize_networks([INPUT_DIR + 'test-data-s1/s1.txt', INPUT_DIR + 'test-data-s2/s2.txt', INPUT_DIR + 'test-data-s3/s3.txt'])
         ml.hac_horizontal(dataframe, OUT_DIR + 'hac-horizontal.png', OUT_DIR + 'hac-clusters-horizontal.txt')