diff --git a/runtimes/mlflow/mlserver_mlflow/runtime.py b/runtimes/mlflow/mlserver_mlflow/runtime.py
index 896d2bf6c..37bf0a039 100644
--- a/runtimes/mlflow/mlserver_mlflow/runtime.py
+++ b/runtimes/mlflow/mlserver_mlflow/runtime.py
@@ -10,7 +10,8 @@
     CONTENT_TYPE_CSV,
     CONTENT_TYPE_JSON,
     parse_csv_input,
-    infer_and_parse_json_input,
+    _split_data_and_params,
+    infer_and_parse_data,
     predictions_to_json,
 )
 
@@ -124,8 +125,10 @@ async def invocations(
         if mime_type == CONTENT_TYPE_CSV:
             csv_input = StringIO(raw_body)
             data = parse_csv_input(csv_input=csv_input, schema=self._input_schema)
+            inference_params = None
         elif mime_type == CONTENT_TYPE_JSON:
-            data = infer_and_parse_json_input(raw_body, self._input_schema)
+            raw_data, inference_params = _split_data_and_params(raw_body)
+            data = infer_and_parse_data(raw_data, self._input_schema)
         else:
             err_message = (
                 "This predictor only supports the following content types, "
@@ -134,7 +137,7 @@ async def invocations(
             raise InferenceError(err_message)
 
         try:
-            raw_predictions = self._model.predict(data)
+            raw_predictions = self._model.predict(data, params=inference_params)
         except MlflowException as e:
             raise InferenceError(e.message)
         except Exception:
diff --git a/runtimes/mlflow/tests/conftest.py b/runtimes/mlflow/tests/conftest.py
index 3c4aa3748..71a713a37 100644
--- a/runtimes/mlflow/tests/conftest.py
+++ b/runtimes/mlflow/tests/conftest.py
@@ -41,9 +41,14 @@ def dataset() -> tuple:
 
 
 @pytest.fixture
-def model_signature(dataset: tuple) -> ModelSignature:
+def default_inference_params() -> dict:
+    return {"foo_param": "foo_value"}
+
+
+@pytest.fixture
+def model_signature(dataset: tuple, default_inference_params: dict) -> ModelSignature:
     X, y = dataset
-    signature = infer_signature(X, y)
+    signature = infer_signature(X, model_output=y, params=default_inference_params)
 
     return signature
 
diff --git a/runtimes/mlflow/tests/test_runtime.py b/runtimes/mlflow/tests/test_runtime.py
index 7090720b5..28f1bb1a2 100644
--- a/runtimes/mlflow/tests/test_runtime.py
+++ b/runtimes/mlflow/tests/test_runtime.py
@@ -1,4 +1,5 @@
 import pytest
+from unittest import mock
 import numpy as np
 import pandas as pd
 
@@ -14,6 +15,7 @@
 )
 from mlflow.pyfunc import PyFuncModel
 from mlflow.models.signature import ModelSignature
+from mlflow.pyfunc.scoring_server import CONTENT_TYPE_CSV, CONTENT_TYPE_JSON
 
 from mlserver_mlflow import MLflowRuntime
 from mlserver_mlflow.codecs import TensorDictCodec
@@ -188,3 +190,70 @@ async def test_metadata(runtime: MLflowRuntime, model_signature: ModelSignature)
 
     assert metadata.parameters is not None
     assert metadata.parameters.content_type == PandasCodec.ContentType
+
+
+@pytest.mark.parametrize(
+    "input, expected",
+    [
+        # works with params:
+        (
+            ['{"instances": [1, 2, 3], "params": {"foo": "bar"}}', CONTENT_TYPE_JSON],
+            {"data": {"foo": [1, 2, 3]}, "params": {"foo": "bar"}},
+        ),
+        (
+            [
+                '{"inputs": [1, 2, 3], "params": {"foo": "bar"}}',
+                CONTENT_TYPE_JSON,
+            ],
+            {"data": {"foo": [1, 2, 3]}, "params": {"foo": "bar"}},
+        ),
+        (
+            [
+                '{"inputs": {"foo": [1, 2, 3]}, "params": {"foo": "bar"}}',
+                CONTENT_TYPE_JSON,
+            ],
+            {"data": {"foo": [1, 2, 3]}, "params": {"foo": "bar"}},
+        ),
+        (
+            [
+                '{"dataframe_split": {'
+                '"columns": ["foo"], '
+                '"data": [1, 2, 3]}, '
+                '"params": {"foo": "bar"}}',
+                CONTENT_TYPE_JSON,
+            ],
+            {"data": {"foo": [1, 2, 3]}, "params": {"foo": "bar"}},
+        ),
+        (
+            [
+                '{"dataframe_records": ['
+                '{"foo": 1}, {"foo": 2}, {"foo": 3}], '
+                '"params": {"foo": "bar"}}',
+                CONTENT_TYPE_JSON,
+            ],
+            {"data": {"foo": [1, 2, 3]}, "params": {"foo": "bar"}},
+        ),
+        (
+            ["foo\n1\n2\n3\n", CONTENT_TYPE_CSV],
+            {"data": {"foo": [1, 2, 3]}, "params": None},
+        ),
+        # works without params:
+        (
+            ['{"instances": [1, 2, 3]}', CONTENT_TYPE_JSON],
+            {"data": {"foo": [1, 2, 3]}, "params": None},
+        ),
+    ],
+)
+async def test_invocation_with_params(
+    runtime: MLflowRuntime,
+    input: list,
+    expected: dict,
+):
+    with mock.patch.object(
+        runtime._model, "predict", return_value=[1, 2, 3]
+    ) as predict_mock:
+        await runtime.invocations(*input)
+        np.testing.assert_array_equal(
+            predict_mock.call_args[0][0].get("foo"), expected["data"]["foo"]
+        )
+        assert predict_mock.call_args.kwargs["params"] == expected["params"]