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INFO:root:Found 200 sentences
{68: {'entities': [three, 3],
'file_path': 'C:\\Users\\shweata\\fun_projects\\corpus\\ethics_statement_10\\PMC8191056\\sections\\1_body\\3_discussion\\1_p.xml',
'has_terms': ['informed consent'],
'labels': ['CARDINAL', 'MONEY'],
'paragraph': 'Nine original statements from the KIDS Framework, and one '
'new statement were validated in this three-round policy '
'Delphi study with pediatric genomic stakeholders in '
'Canada. The three highest ranked statements corresponded '
'to essential elements in the informed consent process, '
'namely evaluation of realistic risk and benefit (Statement '
'#8), transparency about how data will be managed and used '
'(Statement #3), and the possibility of future unspecified '
'use (Statement #5). Lack of consensus and high polarity '
'with respect to Statements #10–12 centered on the '
'relationship between re-identifiability risks, and how '
'access to anonymized and coded genomic data should be '
'managed. The conceptual difficulty and high comprehension '
'level needed to participate meaningfully in shared '
'decision making were likely reasons Statement #2 ranked '
'low despite wider support in the pediatric bioethics '
'literature for children’s engagement in research '
'decisions. The impossibility of withdrawing research data '
'if already aggregated, and an inability to provide a '
'“menu” of data sharing options to accommodate family '
'values likely explain why Statements #4 and 8 ranked among '
'the lowest relative to other Statements.',
'position_end': [9, 234],
'position_start': [4, 233],
'sentence': 'The three highest ranked statements corresponded to '
'essential elements in the informed consent process, namely '
'evaluation of realistic risk and benefit (Statement #8), '
'transparency about how data will be managed and used '
'(Statement #3), and the possibility of future unspecified '
'use (Statement #5).',
'weight': 1},
171: {'entities': [Germany,
the Standing Working Group,
the German Research Ethics Committees,
AKEK,
12 to 16,
14],
'file_path': 'C:\\Users\\shweata\\fun_projects\\corpus\\ethics_statement_10\\PMC8283995\\sections\\1_body\\2_background\\3_study_aims_and_research_q\\1_p.xml',
'has_terms': ['ethics committee', 'ethics committees'],
'labels': ['GPE', 'ORG', 'ORG', 'ORG', 'DATE', 'CARDINAL'],
'paragraph': 'To harmonise paediatric research consent-procedures '
'across Germany, the Standing Working Group of the German '
'Research Ethics Committees (AKEK) advocates using a '
'national template consent-form which aims to provide '
'information for adolescents aged 12 to 16 and can be '
'adapted to fit the study designs of most clinical trials '
'[ 14].',
'position_end': [66, 94, 135, 141, 255, 328],
'position_start': [59, 68, 98, 137, 247, 326],
'sentence': 'To harmonise paediatric research consent-procedures across '
'Germany, the Standing Working Group of the German Research '
'Ethics Committees (AKEK) advocates using a national '
'template consent-form which aims to provide information '
'for adolescents aged 12 to 16 and can be adapted to fit '
'the study designs of most clinical trials [ 14].',
'weight': 2},
175: {'entities': [D414/16,
01.01.2016,
years 6 to 9,
Gymnasium,
Germany,
March 2016],
'file_path': 'C:\\Users\\shweata\\fun_projects\\corpus\\ethics_statement_10\\PMC8283995\\sections\\1_body\\3_methods\\1_study_design\\1_p.xml',
'has_terms': ['ethics committee'],
'labels': ['GPE', 'ORDINAL', 'DATE', 'GPE', 'GPE', 'DATE'],
'paragraph': 'Participants were adolescents and thus require parental '
'consent to participate in a research study. Therefore, we '
'drew a convenience sample utilizing the structural '
'advantages of a school setting. Original questionnaire '
'items were designed to match the aims of our empirical '
'study. Following approval of the study by the local '
'ethics committee (D414/16, 01.01.2016), years 6 to 9 of a '
'secondary school (Gymnasium) in northern Germany were '
'approached for participation (in March 2016). Parents '
'were asked to give written consent, and to answer '
'questions regarding their child’s medical background. Of '
'450 parents, 315 (78.00%) consented to their child’s '
'participation, with 279 children (88.57%) then completing '
'the questionnaire (36 eligible children were not in class '
'on the day the survey took place).',
'position_end': [70, 82, 97, 130, 151, 200],
'position_start': [63, 72, 85, 121, 144, 190],
'sentence': 'Following approval of the study by the local ethics '
'committee (D414/16, 01.01.2016), years 6 to 9 of a '
'secondary school (Gymnasium) in northern Germany were '
'approached for participation (in March 2016).',
'weight': 1},
195: {'entities': [18],
'file_path': 'C:\\Users\\shweata\\fun_projects\\corpus\\ethics_statement_10\\PMC8283995\\sections\\1_body\\6_discussion\\1_p.xml',
'has_terms': ['informed consent'],
'labels': ['CARDINAL'],
'paragraph': 'The need for more clinical research with minors is '
'evident [ 1, 2], and was addressed in recent EU '
'legislation. Although their right to have a say in the '
'decision-making process is ethically and legally well '
'established, consensus as to best practice in ensuring '
'children’s and adolescents’ informed consent has yet to '
'be reached (e.g., [ 18]). Interview studies (e.g., [ 19– '
'23]), which are mostly qualitative and use smaller '
'numbers of participants, have highlighted issues of '
'concern.',
'position_end': [229],
'position_start': [227],
'sentence': 'Although their right to have a say in the decision-making '
'process is ethically and legally well established, '
'consensus as to best practice in ensuring children’s and '
'adolescents’ informed consent has yet to be reached (e.g., '
'[ 18]).',
'weight': 1},
199: {'entities': [AKEK],
'file_path': 'C:\\Users\\shweata\\fun_projects\\corpus\\ethics_statement_10\\PMC8283995\\sections\\1_body\\8_conclusion\\1_p.xml',
'has_terms': ['informed consent'],
'labels': ['ORG'],
'paragraph': 'Our study has shown that the template consent-form '
'designed by the AKEK provides age-appropriate information '
'allowing the envisioned age group to give informed '
'consent. Our findings further strengthen the proposition '
'that from the age of 12\xa0years onwards adolescents are '
'able to understand the main elements of a consent-form '
'and to make an informed decision (e.g., [ 39]).',
'position_end': [71],
'position_start': [67],
'sentence': 'Our study has shown that the template consent-form '
'designed by the AKEK provides age-appropriate information '
'allowing the envisioned age group to give informed '
'consent.',
'weight': 1}}