<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<scenario xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" analysisNo="0" name="R0670" schemaVersion="26" wuID="0" xsi:noNamespaceSchemaLocation="scenario_26.xsd">
  <demography maximumAgeYrs="90" name="Ifakara" popSize="1000">
    <ageGroup lowerbound="0">
      <group poppercent="3.474714994" upperbound="1"/>
      <group poppercent="12.76004028" upperbound="5"/>
      <group poppercent="14.52151394" upperbound="10"/>
      <group poppercent="12.75565434" upperbound="15"/>
      <group poppercent="10.836323739999999" upperbound="20"/>
      <group poppercent="8.393312454" upperbound="25"/>
      <group poppercent="7.001421452" upperbound="30"/>
      <group poppercent="5.800587654" upperbound="35"/>
      <group poppercent="5.102136612" upperbound="40"/>
      <group poppercent="4.182561874" upperbound="45"/>
      <group poppercent="3.339409351" upperbound="50"/>
      <group poppercent="2.986112356" upperbound="55"/>
      <group poppercent="2.555766582" upperbound="60"/>
      <group poppercent="2.332763433" upperbound="65"/>
      <group poppercent="1.77400255" upperbound="70"/>
      <group poppercent="1.008525491" upperbound="75"/>
      <group poppercent="0.74167341" upperbound="80"/>
      <group poppercent="0.271863401" upperbound="85"/>
      <group poppercent="0.161614642" upperbound="90"/>
    </ageGroup>
  </demography>
  <monitoring name="Quarterly Surveys">
    <SurveyOptions>
      <option name="nHost" value="true"/>
      <option name="nUncomp" value="true"/>
      <option name="nSevere" value="true"/>
    </SurveyOptions>
    <surveys detectionLimit="40">
      <surveyTime>1</surveyTime>
      <surveyTime>19</surveyTime>
      <surveyTime>37</surveyTime>
      <surveyTime>55</surveyTime>
      <surveyTime>74</surveyTime>
      <surveyTime>92</surveyTime>
      <surveyTime>110</surveyTime>
      <surveyTime>128</surveyTime>
      <surveyTime>147</surveyTime>
      <surveyTime>165</surveyTime>
      <surveyTime>183</surveyTime>
      <surveyTime>201</surveyTime>
      <surveyTime>220</surveyTime>
      <surveyTime>238</surveyTime>
      <surveyTime>256</surveyTime>
      <surveyTime>274</surveyTime>
      <surveyTime>293</surveyTime>
      <surveyTime>311</surveyTime>
      <surveyTime>329</surveyTime>
      <surveyTime>347</surveyTime>
      <surveyTime>366</surveyTime>
      <surveyTime>384</surveyTime>
      <surveyTime>402</surveyTime>
      <surveyTime>420</surveyTime>
      <surveyTime>439</surveyTime>
      <surveyTime>457</surveyTime>
      <surveyTime>475</surveyTime>
      <surveyTime>493</surveyTime>
      <surveyTime>512</surveyTime>
      <surveyTime>530</surveyTime>
      <surveyTime>548</surveyTime>
      <surveyTime>566</surveyTime>
      <surveyTime>585</surveyTime>
      <surveyTime>603</surveyTime>
      <surveyTime>621</surveyTime>
      <surveyTime>639</surveyTime>
      <surveyTime>658</surveyTime>
      <surveyTime>676</surveyTime>
      <surveyTime>694</surveyTime>
      <surveyTime>712</surveyTime>
      <surveyTime>731</surveyTime>
      <surveyTime>749</surveyTime>
      <surveyTime>767</surveyTime>
      <surveyTime>785</surveyTime>
      <surveyTime>804</surveyTime>
      <surveyTime>822</surveyTime>
      <surveyTime>840</surveyTime>
      <surveyTime>858</surveyTime>
      <surveyTime>877</surveyTime>
      <surveyTime>895</surveyTime>
      <surveyTime>913</surveyTime>
      <surveyTime>931</surveyTime>
      <surveyTime>950</surveyTime>
      <surveyTime>968</surveyTime>
      <surveyTime>986</surveyTime>
      <surveyTime>1004</surveyTime>
      <surveyTime>1023</surveyTime>
      <surveyTime>1041</surveyTime>
      <surveyTime>1059</surveyTime>
      <surveyTime>1077</surveyTime>
      <surveyTime>1096</surveyTime>
      <surveyTime>1114</surveyTime>
      <surveyTime>1132</surveyTime>
      <surveyTime>1150</surveyTime>
      <surveyTime>1169</surveyTime>
      <surveyTime>1187</surveyTime>
      <surveyTime>1205</surveyTime>
      <surveyTime>1223</surveyTime>
      <surveyTime>1242</surveyTime>
      <surveyTime>1260</surveyTime>
      <surveyTime>1278</surveyTime>
      <surveyTime>1296</surveyTime>
      <surveyTime>1315</surveyTime>
      <surveyTime>1333</surveyTime>
      <surveyTime>1351</surveyTime>
      <surveyTime>1369</surveyTime>
      <surveyTime>1388</surveyTime>
      <surveyTime>1406</surveyTime>
      <surveyTime>1424</surveyTime>
      <surveyTime>1442</surveyTime>
      <surveyTime>1461</surveyTime>
    </surveys>
    <ageGroup lowerbound="0">
      <group upperbound="0.25"/>
      <group upperbound="0.5"/>
      <group upperbound="0.75"/>
      <group upperbound="1"/>
      <group upperbound="1.5"/>
      <group upperbound="2"/>
      <group upperbound="3"/>
      <group upperbound="4"/>
      <group upperbound="5"/>
      <group upperbound="6"/>
      <group upperbound="7"/>
      <group upperbound="8"/>
      <group upperbound="9"/>
      <group upperbound="10"/>
      <group upperbound="12"/>
      <group upperbound="14"/>
      <group upperbound="16"/>
      <group upperbound="18"/>
      <group upperbound="20"/>
      <group upperbound="25"/>
      <group upperbound="30"/>
      <group upperbound="35"/>
      <group upperbound="40"/>
      <group upperbound="45"/>
      <group upperbound="50"/>
      <group upperbound="55"/>
      <group upperbound="60"/>
      <group upperbound="65"/>
      <group upperbound="70"/>
      <group upperbound="99"/>
    </ageGroup>
  </monitoring>
  <interventions name="Full Set">
    <descriptions/>
  </interventions>
  <healthSystem>
    <ImmediateOutcomes name="Reference low">
      <drugRegimen firstLine="ACT" inpatient="QN" secondLine="ACT"/>
      <initialACR>
        <ACT value="0.98"/>
        <QN value="0.998"/>
        <selfTreatment value="0.63"/>
      </initialACR>
      <compliance>
        <ACT value="0.9"/>
        <selfTreatment value="0.85"/>
      </compliance>
      <nonCompliersEffective>
        <ACT value="0.2"/>
        <selfTreatment value="0"/>
      </nonCompliersEffective>
      <pSeekOfficialCareUncomplicated1 value="0.015"/>
      <pSelfTreatUncomplicated value="0.05"/>
      <pSeekOfficialCareUncomplicated2 value="0.015"/>
      <pSeekOfficialCareSevere value="0.48"/>
    </ImmediateOutcomes>
    <CFR>
      <group lowerbound="0" value="0.09189"/>
      <group lowerbound="0.25" value="0.0810811"/>
      <group lowerbound="0.75" value="0.0648649"/>
      <group lowerbound="1.5" value="0.0689189"/>
      <group lowerbound="2.5" value="0.0675676"/>
      <group lowerbound="3.5" value="0.0297297"/>
      <group lowerbound="4.5" value="0.0459459"/>
      <group lowerbound="7.5" value="0.0945946"/>
      <group lowerbound="12.5" value="0.1243243"/>
      <group lowerbound="15" value="0.1378378"/>
    </CFR>
    <pSequelaeInpatient>
      <group lowerbound="0.0" value="0.0132"/>
      <group lowerbound="5.0" value="0.005"/>
    </pSequelaeInpatient>
  </healthSystem>
  <entoData mode="4" name="Namawala">
    <vector>
      <anopheles mosquito="gambiae_ss" propInfected="0.078" propInfectious="0.021">
        <eir EIRRotateAngle="0" a0="-10.92583484" a1="0.8968" a2="-0.4551" b1="2.678" b2="2.599"/>
        <mosq extrinsicIncubationPeriod="11" minInfectedThreshold="0.01" mosqHumanBloodIndex="0.939" mosqLaidEggsSameDayProportion="0.313" mosqProbBiting="0.95" mosqProbFindRestSite="0.95" mosqProbOvipositing="0.88" mosqProbResting="0.99" mosqRestDuration="3" mosqSeekingDuration="0.33" mosqSurvivalFeedingCycleProbability="0.623"/>
        <nonHumanHosts mosqProbBiting="0.95" mosqProbFindRestSite="0.95" mosqProbResting="0.99" mosqRelativeEntoAvailability="1.0" name="unprotectedAnimals"/>
      </anopheles>
      <anopheles mosquito="funestus" propInfected="0.078" propInfectious="0.021">
        <eir EIRRotateAngle="0" a0="-9.943834842" a1="-4.546" a2="-0.2198" b1="2.252" b2="-0.00743"/>
        <mosq extrinsicIncubationPeriod="11" minInfectedThreshold="0.01" mosqHumanBloodIndex="0.98" mosqLaidEggsSameDayProportion="0.616" mosqProbBiting="0.95" mosqProbFindRestSite="0.95" mosqProbOvipositing="0.88" mosqProbResting="0.99" mosqRestDuration="3" mosqSeekingDuration="0.33" mosqSurvivalFeedingCycleProbability="0.611"/>
        <nonHumanHosts mosqProbBiting="0.95" mosqProbFindRestSite="0.95" mosqProbResting="0.99" mosqRelativeEntoAvailability="1.0" name="unprotectedAnimals"/>
      </anopheles>
      <anopheles mosquito="arabiensis" propInfected="0.078" propInfectious="0.021">
        <eir EIRRotateAngle="0" a0="-8.729834842" a1="0.8968" a2="-0.4551" b1="2.678" b2="2.599"/>
        <mosq extrinsicIncubationPeriod="11" minInfectedThreshold="0.01" mosqHumanBloodIndex="0.871" mosqLaidEggsSameDayProportion="0.313" mosqProbBiting="0.95" mosqProbFindRestSite="0.95" mosqProbOvipositing="0.88" mosqProbResting="0.99" mosqRestDuration="3" mosqSeekingDuration="0.33" mosqSurvivalFeedingCycleProbability="0.623"/>
        <nonHumanHosts mosqProbBiting="0.95" mosqProbFindRestSite="0.95" mosqProbResting="0.99" mosqRelativeEntoAvailability="1.0" name="unprotectedAnimals"/>
      </anopheles>
      <nonHumanHosts name="unprotectedAnimals" number="1.0"/>
    </vector>
  </entoData>
  <model>
    <ModelOptions>
      <option name="COMORB_HET" value="true"/>
    </ModelOptions>
    <clinical healthSystemMemory="6"/>
    <human>
      <availabilityToMosquitoes>
        <group lowerbound="0.0" value="0.225940909648"/>
        <group lowerbound="1.0" value="0.286173633441"/>
        <group lowerbound="2.0" value="0.336898395722"/>
        <group lowerbound="3.0" value="0.370989854675"/>
        <group lowerbound="4.0" value="0.403114915112"/>
        <group lowerbound="5.0" value="0.442585112522"/>
        <group lowerbound="6.0" value="0.473839351511"/>
        <group lowerbound="7.0" value="0.512630464378"/>
        <group lowerbound="8.0" value="0.54487872702"/>
        <group lowerbound="9.0" value="0.581527755812"/>
        <group lowerbound="10.0" value="0.630257580698"/>
        <group lowerbound="11.0" value="0.663063362714"/>
        <group lowerbound="12.0" value="0.702417432755"/>
        <group lowerbound="13.0" value="0.734605377277"/>
        <group lowerbound="14.0" value="0.788908765653"/>
        <group lowerbound="15.0" value="0.839587932303"/>
        <group lowerbound="20.0" value="1.0"/>
        <group lowerbound="20.0" value="1.0"/>
      </availabilityToMosquitoes>
    </human>
    <parameters interval="5" iseed="0" latentp="3">
      <!-- run id=670 modelVersion="65536"  terization id=243515 sampling date=2009-10-30 12:12:09 lossfunction=51.528676 -->
      <parameter include="0" name="'-ln(1-Sinf)'" number="1" value="0.050736"/>
      <parameter include="0" name="Estar" number="2" value="0.03247"/>
      <parameter include="1" name="Simm" number="3" value="0.137683"/>
      <parameter include="1" name="Xstar_p" number="4" value="103655.671385"/>
      <parameter include="1" name="gamma_p" number="5" value="1.896909"/>
      <parameter include="1" name="sigma2i" number="6" value="9.806297"/>
      <parameter include="1" name="CumulativeYstar" number="7" value="73779278.7284"/>
      <parameter include="1" name="CumulativeHstar" number="8" value="80.847454"/>
      <parameter include="1" name="'-ln(1-alpha_m)'" number="9" value="2.446014"/>
      <parameter include="1" name="decay_m" number="10" value="2.333199"/>
      <parameter include="1" name="sigma2_0" number="11" value="0.659768"/>
      <parameter include="1" name="Xstar_v" number="12" value="0.920756"/>
      <parameter include="1" name="Ystar2" number="13" value="11434.16373"/>
      <parameter include="1" name="alpha" number="14" value="120493.490866"/>
      <parameter include="1" name="Density bias (non Garki)" number="15" value="0.125403"/>
      <parameter include="0" name="No Use 1" number="16" value="1.0"/>
      <parameter include="1" name="log oddsr CF community" number="17" value="0.717428"/>
      <parameter include="1" name="Indirect risk cofactor" number="18" value="0.010192"/>
      <parameter include="1" name="Non-malaria infant mortality" number="19" value="56.223778"/>
      <parameter include="1" name="Density bias (Garki)" number="20" value="4.683531"/>
      <parameter include="1" name="Severe Malaria Threshhold" number="21" value="340339.246262"/>
      <parameter include="0" name="Immunity Penalty" number="22" value="1.0"/>
      <parameter include="0" name="Immune effector decay" number="23" value="0.0"/>
      <parameter include="1" name="comorbidity intercept" number="24" value="0.092092"/>
      <parameter include="1" name="Ystar half life" number="25" value="0.296711"/>
      <parameter include="1" name="Ystar1" number="26" value="0.599067"/>
      <parameter include="0" name="Asex immune decay" number="27" value="0.0"/>
      <parameter include="1" name="Ystar0" number="28" value="215.488654"/>
      <parameter include="1" name="Idete multiplier" number="29" value="2.692999"/>
      <parameter include="1" name="critical age for comorbidity" number="30" value="0.130409"/>
    </parameters>
  </model>
</scenario>
