diff --git a/.github/workflows/continuous-integration.yml b/.github/workflows/continuous-integration.yml
index f54553da4..a1d7fb7d6 100644
--- a/.github/workflows/continuous-integration.yml
+++ b/.github/workflows/continuous-integration.yml
@@ -63,7 +63,7 @@ jobs:
       matrix:
         os: [ubuntu, windows]
         # Don't forget to add all new flavors to this list!
-        flavor: [1, 2, 3, 4, 5]
+        flavor: [1, 2, 3, 4, 5, 6]
         include:
           # Node 16
           - flavor: 1
@@ -87,10 +87,16 @@ jobs:
             nodeFlag: 18
             typescript: next
             typescriptFlag: next
-          # Node nightly
+          # Node 20
           - flavor: 5
-            node: 20-nightly
-            nodeFlag: 20_nightly
+            node: 20
+            nodeFlag: 20
+            typescript: latest
+            typescriptFlag: latest
+          # Node nightly
+          - flavor: 6
+            node: 21-nightly
+            nodeFlag: 21_nightly
             typescript: latest
             typescriptFlag: latest
     steps:
diff --git a/node20/tsconfig.json b/node20/tsconfig.json
new file mode 100644
index 000000000..b99454516
--- /dev/null
+++ b/node20/tsconfig.json
@@ -0,0 +1,3 @@
+{
+  "extends": "@tsconfig/node20/tsconfig.json"
+}
diff --git a/package.json b/package.json
index dc0ea0d92..c55deb400 100644
--- a/package.json
+++ b/package.json
@@ -30,7 +30,8 @@
     "./transpilers/swc-experimental": "./transpilers/swc-experimental.js",
     "./node14/tsconfig.json": "./node14/tsconfig.json",
     "./node16/tsconfig.json": "./node16/tsconfig.json",
-    "./node18/tsconfig.json": "./node18/tsconfig.json"
+    "./node18/tsconfig.json": "./node18/tsconfig.json",
+    "./node20/tsconfig.json": "./node20/tsconfig.json"
   },
   "types": "dist/index.d.ts",
   "bin": {
@@ -55,7 +56,8 @@
     "/tsconfig.schemastore-schema.json",
     "/node14/",
     "/node16/",
-    "/node18/"
+    "/node18/",
+    "/node20/"
   ],
   "scripts": {
     "lint": "dprint check",
@@ -161,6 +163,7 @@
     "@tsconfig/node14": "*",
     "@tsconfig/node16": "*",
     "@tsconfig/node18": "*",
+    "@tsconfig/node20": "*",
     "acorn": "^8.4.1",
     "acorn-walk": "^8.1.1",
     "arg": "^4.1.0",
diff --git a/src/test/package.spec.ts b/src/test/package.spec.ts
index 5b1835e17..f3ab07e6f 100644
--- a/src/test/package.spec.ts
+++ b/src/test/package.spec.ts
@@ -49,4 +49,5 @@ test('should export all CJS entrypoints', () => {
   testsDirRequire.resolve('ts-node/node14/tsconfig.json');
   testsDirRequire.resolve('ts-node/node16/tsconfig.json');
   testsDirRequire.resolve('ts-node/node18/tsconfig.json');
+  testsDirRequire.resolve('ts-node/node20/tsconfig.json');
 });
diff --git a/src/test/tsconfig-bases.spec.ts b/src/test/tsconfig-bases.spec.ts
index 29b4edc67..4ec8e8b61 100644
--- a/src/test/tsconfig-bases.spec.ts
+++ b/src/test/tsconfig-bases.spec.ts
@@ -27,7 +27,7 @@ test.suite('should use implicit @tsconfig/bases config when one is not loaded fr
     lib = 'es2023';
   }
 
-  test('implicitly uses @tsconfig/node14, @tsconfig/node16, or @tsconfig/node18 compilerOptions when both TS and node versions support it', async (t) => {
+  test('implicitly uses @tsconfig/node14, @tsconfig/node16, @tsconfig/node18, or @tsconfig/node20 compilerOptions when both TS and node versions support it', async (t) => {
     const r1 = await exec(`${BIN_PATH} --showConfig`, {
       cwd: t.context.tmpDir,
     });
@@ -94,4 +94,5 @@ test.suite('should bundle @tsconfig/bases to be used in your own tsconfigs', (te
   test(`ts-node/node14/tsconfig.json`, macro, 'node14');
   test(`ts-node/node16/tsconfig.json`, macro, 'node16');
   test(`ts-node/node18/tsconfig.json`, macro, 'node18');
+  test(`ts-node/node20/tsconfig.json`, macro, 'node20');
 });
diff --git a/src/tsconfigs.ts b/src/tsconfigs.ts
index 691cce7b6..5248befb9 100644
--- a/src/tsconfigs.ts
+++ b/src/tsconfigs.ts
@@ -8,6 +8,10 @@ const nodeMajor = parseInt(process.versions.node.split('.')[0], 10);
  */
 export function getDefaultTsconfigJsonForNodeVersion(ts: TSCommon): any {
   const tsInternal = ts as any as TSInternal;
+  if (nodeMajor >= 20) {
+    const config = require('@tsconfig/node20/tsconfig.json');
+    if (configCompatible(config)) return config;
+  }
   if (nodeMajor >= 18) {
     const config = require('@tsconfig/node18/tsconfig.json');
     if (configCompatible(config)) return config;
diff --git a/tests/tsconfig-bases/node20/tsconfig.json b/tests/tsconfig-bases/node20/tsconfig.json
new file mode 100644
index 000000000..dd64cc1e4
--- /dev/null
+++ b/tests/tsconfig-bases/node20/tsconfig.json
@@ -0,0 +1,3 @@
+{
+  "extends": "ts-node/node20/tsconfig.json"
+}
diff --git a/yarn.lock b/yarn.lock
index 22468f8f5..035ecbe33 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -654,6 +654,13 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@tsconfig/node20@npm:*":
+  version: 1.0.0
+  resolution: "@tsconfig/node20@npm:1.0.0"
+  checksum: bb2f9ffeb73d1317f3ebfb260109b5e382cab228da2bc8b6202979605820a771fa7cf7a8defc19c9c9ae9d91d6da7b586ca3d9a1e7e1547af6a5118c462bacef
+  languageName: node
+  linkType: hard
+
 "@types/argparse@npm:1.0.38":
   version: 1.0.38
   resolution: "@types/argparse@npm:1.0.38"
@@ -3812,6 +3819,7 @@ __metadata:
     "@tsconfig/node14": "*"
     "@tsconfig/node16": "*"
     "@tsconfig/node18": "*"
+    "@tsconfig/node20": "*"
     "@types/diff": ^4.0.2
     "@types/lodash": ^4.14.151
     "@types/node": 13.13.5