Unbelieveble

[GitOguz]

Never in my whole life have I had to install or try to get such a difficult application combination to work. 100,000 different packages and libraries, with prehistoric versions that are not even up to date. It's 2025, and NONMEM still uses MPICH2 1.x.x, which is ancient. Meanwhile, version 4 is available. PsN is left in the dark.

I invest in expensive hardware to run NONMEM jobs with multiple nodes. Each server is dual-socket. To use all its capacity, you need MPI. The complexity of PsN and how it can run multi-node, multi-socket MPI jobs is beyond me. Everything is installed, and MPI tests without NONMEM work fine. But with NONMEM, it’s a complete error cascade. I have no clue where to even begin.

For example, if you have 2 nodes, each with 2 CPUs (2 x 64 = 128 threads per node), giving a total of 256 threads across 2 nodes, how do you even run a parallel job using PsN with a 2-node cluster?