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Dataset Level Clinical Page #281

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bencap opened this issue Oct 1, 2024 · 0 comments
Open
10 tasks

Dataset Level Clinical Page #281

bencap opened this issue Oct 1, 2024 · 0 comments
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app: frontend Task implementation touches the frontend type: discussion Team discussion required type: feature New feature workstream: clinical Task relates to clinical features workstream: pillar Task relates to pillar project

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@bencap
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bencap commented Oct 1, 2024

This page should summarize important and relevant clinical information available for a given score set. At a minimum, we should:

  • Integrate existing clinical visualizations in the mave-viz branch (including, but not limited to: a histogram of syn/nonsense variants, a histogram of known clinical variants with filters for clinvar stars and classification dates)
  • Display the transcript to used for the target (or the transcript to which this target mapped)

We may include, at a lower priority:

  • Add a histogram or scatterplot able to compare this data to other datasets and/or models
  • Add a calculation and display/visualization for odds of pathogenicity
  • Summarize the assay and provide a star rating (this star rating will likely stem from the adherance to our minimum information standards)
  • Fields from the clingen functional assay worksheet
  • Model organism data
  • cell engineering data (transgene vs. editing endogenous locus)
  • Read out (??) and repoducibility
  • Links to other datasets which include the same gene and/or variants
@bencap bencap added type: feature New feature workstream: clinical Task relates to clinical features app: frontend Task implementation touches the frontend workstream: pillar Task relates to pillar project type: discussion Team discussion required labels Oct 1, 2024
@bencap bencap changed the title Integrate Preview Visualizations with MaveDB Dataset Level Clinical Page Oct 1, 2024
@bencap bencap added this to the Pillar Project milestone Oct 2, 2024
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Labels
app: frontend Task implementation touches the frontend type: discussion Team discussion required type: feature New feature workstream: clinical Task relates to clinical features workstream: pillar Task relates to pillar project
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