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Possible NTR: anterior segment mesenchyme (ASM) #178

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LeylaR opened this issue Jul 25, 2024 · 1 comment
Open

Possible NTR: anterior segment mesenchyme (ASM) #178

LeylaR opened this issue Jul 25, 2024 · 1 comment
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@LeylaR
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LeylaR commented Jul 25, 2024

Should anterior segment mesenchyme be added to the AO? The anterior segment mesenchyme derives from the periocular mesenchyme (POM) and gives rise to some components of the anterior segment (AS).
Anterior segment mesenchyme is described and characterized in 3 publications (PubMed IDs 32528955, 36563566, 37024546) from the Famulski lab:

Van Der Meulen, K.L., Vöcking, O., Weaver, M.L., Meshram, N.N., Famulski, J.K. (2020) Spatiotemporal Characterization of Anterior Segment Mesenchyme Heterogeneity During Zebrafish Ocular Anterior Segment Development. Frontiers in cell and developmental biology. 8:379.
https://zfin.org/ZDB-PUB-200613-8
PMID 32528955

Vöcking, O., Van Der Meulen, K., Patel, M.K., Famulski, J.K. (2022) Zebrafish anterior segment mesenchyme progenitors are defined by function of tfap2a but not sox10. Differentiation; research in biological diversity. 130:324232-42.
https://zfin.org/ZDB-PUB-221224-39
PMID 36563566

Vöcking, O., Famulski, J.K. (2023) A temporal single cell transcriptome atlas of zebrafish anterior segment development. Scientific Reports. 13:56565656.
https://zfin.org/ZDB-PUB-230407-53
PMID 37024546

@cerivs cerivs self-assigned this Sep 13, 2024
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cerivs commented Oct 28, 2024

Maybe. Anterior segment mesenchyme would develop from periocular mesenchyme. POC should have relationship with some cranial nnc if we make the ASM term so we can have development tree. Def from ZDB-PUB-230407-53 ASM is composed of POM cells which have committed to the AS fate and migrated to the AS space.

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