diff --git a/OADB/AliEventCuts.cxx b/OADB/AliEventCuts.cxx
index 1e41c42ab56..398a9db992f 100644
--- a/OADB/AliEventCuts.cxx
+++ b/OADB/AliEventCuts.cxx
@@ -72,6 +72,7 @@ AliEventCuts::AliEventCuts(bool saveplots) : TList(),
   fUseVariablesCorrelationCuts{false},
   fUseEstimatorsCorrelationCut{false},
   fUseStrongVarCorrelationCut{false},
+  fUseITSTPCCluCorrelationCut{false},
   fEstimatorsCorrelationCoef{0.,1.},
   fEstimatorsSigmaPars{10000.,0.,0.,0.},
   fDeltaEstimatorNsigma{1.,1.},
@@ -82,6 +83,7 @@ AliEventCuts::AliEventCuts(bool saveplots) : TList(),
   fMultiplicityV0McorrCut{nullptr},
   fFB128vsTrklLinearCut{1.e8,0.},
   fVZEROvsTPCoutPolCut{1.e8,0.,0.,0.,0.},
+  fITSvsTPCcluPolCut{0.,0.,0.},
   fRequireExactTriggerMask{false},
   fTriggerMask{AliVEvent::kAny},
   fTriggerClasses{},
@@ -226,6 +228,12 @@ bool AliEventCuts::AcceptEvent(AliVEvent *ev) {
   bool usePileUpSPD = (fUseCombinedMVSPDcut && vtx == vtSPD) || fUseSPDpileUpCut;
   AliVMultiplicity* mult = ev->GetMultiplicity();
   const int ntrkl = mult->GetNumberOfTracklets();
+  int nCluSDDSSD=0;
+  for(Int_t iLay=2; iLay<6; iLay++) nCluSDDSSD+=mult->GetNumberOfITSClusters(iLay);
+  int nCluTPC=0;
+  if (dynamic_cast<AliAODEvent*>(ev)) nCluTPC=dynamic_cast<AliAODEvent*>(ev)->GetNumberOfTPCClusters();
+  else if (dynamic_cast<AliESDEvent*>(ev)) nCluTPC=dynamic_cast<AliESDEvent*>(ev)->GetNumberOfTPCClusters();
+
   if (fUseMultiplicityDependentPileUpCuts) {
     if (ntrkl < 20) fSPDpileupMinContributors = 3;
     else if (ntrkl < 50) fSPDpileupMinContributors = 4;
@@ -235,6 +243,9 @@ bool AliEventCuts::AcceptEvent(AliVEvent *ev) {
       (!fTrackletBGcut || !fUtils.IsSPDClusterVsTrackletBG(ev)) &&
       (!usePileUpMV || !fUtils.IsPileUpMV(ev)))
     fFlag |= BIT(kPileUp);
+  
+  const double its_tpcclus_limit = PolN(double(nCluTPC),fITSvsTPCcluPolCut,2);
+  if(!fUseITSTPCCluCorrelationCut || (nCluSDDSSD > its_tpcclus_limit)) fFlag |= BIT(kTPCPileUp);
 
   /// Centrality cuts:
   /// * Check for min and max centrality
@@ -790,7 +801,10 @@ void AliEventCuts::SetupPbPb2018() {
 
   array<double,5> vzero_tpcout_polcut = {-2000.,2.1,3.5e-5,0.,0.};
   std::copy(vzero_tpcout_polcut.begin(),vzero_tpcout_polcut.end(),fVZEROvsTPCoutPolCut);
-
+  
+  array<double,3> its_tpcclus_polcut = {-3000.,0.0099,9.426e-10};
+  std::copy(its_tpcclus_polcut.begin(),its_tpcclus_polcut.end(),fITSvsTPCcluPolCut);
+  
   if (fCentralityFramework != 0) {
     if(!fMultiplicityV0McorrCut) fMultiplicityV0McorrCut = new TF1("fMultiplicityV0McorrCut","[0]+[1]*x+[2]*exp([3]-[4]*x) - 5.*([5]+[6]*exp([7]-[8]*x))",0,100);
     fMultiplicityV0McorrCut->SetParameters(-6.15980e+02, 4.89828e+00, 4.84776e+03, -5.22988e-01, 3.04363e-02, -1.21144e+01, 2.95321e+02, -9.20062e-01, 2.17372e-02);
diff --git a/OADB/AliEventCuts.h b/OADB/AliEventCuts.h
index 70ef15cd46c..9377a7dc3e4 100644
--- a/OADB/AliEventCuts.h
+++ b/OADB/AliEventCuts.h
@@ -69,6 +69,7 @@ class AliEventCuts : public TList {
       kCorrelations,
       kTimeRangeCut,
       kEMCALEDCut,
+      kTPCPileUp,
       kAllCuts
     };
 
@@ -168,6 +169,7 @@ class AliEventCuts : public TList {
     bool          fUseVariablesCorrelationCuts;   ///< Switch on/off the cuts on the correlation between event variables
     bool          fUseEstimatorsCorrelationCut;   ///< Switch on/off the cut on the correlation between centrality estimators
     bool          fUseStrongVarCorrelationCut;    ///< Switch on/off the strong cuts on the correlation between event variables
+    bool          fUseITSTPCCluCorrelationCut;    ///< Switch on/off the strong cuts on the correlation between event variables
     double        fEstimatorsCorrelationCoef[2];  ///< fCentEstimators[0] = [0] + [1] * fCentEstimators[1]
     double        fEstimatorsSigmaPars[4];        ///< Sigma parametrisation fCentEstimators[1] vs fCentEstimators[0]
     double        fDeltaEstimatorNsigma[2];       ///< Number of sigma to cut on fCentEstimators[1] vs fCentEstimators[0]
@@ -178,7 +180,8 @@ class AliEventCuts : public TList {
     TF1          *fMultiplicityV0McorrCut;        //!<! Cut on the FB128 vs V0M plane
     double        fFB128vsTrklLinearCut[2];       ///< Cut on the FB128 vs Tracklet plane
     double        fVZEROvsTPCoutPolCut[5];        ///< Cut on VZERO multipliciy vs the number of tracks with kTPCout on
-
+    double        fITSvsTPCcluPolCut[3];          ///< Cut on SDD+SSD clusters vs TPC clusters
+    
     bool          fRequireExactTriggerMask;       ///< If true the event selection mask is required to be equal to fTriggerMask
     unsigned long fTriggerMask;                   ///< Trigger mask
     std::vector<std::string> fTriggerClasses;     ///< Trigger classes
@@ -239,7 +242,7 @@ class AliEventCuts : public TList {
     AliESDtrackCuts* fFB32trackCuts; //!<! Cuts corresponding to FB32 in the ESD (used only for correlations cuts in ESDs)
     AliESDtrackCuts* fTPConlyCuts;   //!<! Cuts corresponding to the standalone TPC cuts in the ESDs (used only for correlations cuts in ESDs)
 
-    ClassDef(AliEventCuts, 13)
+    ClassDef(AliEventCuts, 14)
 };
 
 template<typename F> F AliEventCuts::PolN(F x,F* coef, int n) {