NCA failed with some data. #1
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Thanks for sharing your issue. However, the following codes performed NCA without any errors. We could not reproduce the error you got. Would you please provide the full script and the output of library(readxl)
library(NonCompart)
Data = as.data.frame(read_excel('fail1.xlsx'))
Res = tblNCA(Data, key=c("Subject", "Period", "Formulation"),
colTime="Time", colConc="Concentration",
dose=150, doseUnit="ug", concUnit="ug/mL", R2ADJ=0)
knitr::kable(head(Res[ , 1:10]))
Environmentdevtools::session_info() |
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I have the same error message. |
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Error in |
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@nskoch , It's mainly due to an input of the It would be nice if you could provide minimal working example (MWE), and I will sort out the problem for you. Pil |
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Hi
I work with simulated data, 2 groups of subjects (n=2x500) with 2 full
profiles by subject.
When I limit my dataset to 20 pk profiles, it runs bu I have to define the
slope manually which is not possible for 1000 subject.
My interest is on AUCall, Tmax and Cmax, I do not need slope. Is it
possible with the package ?
Best regards
Nicolas
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
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Le sam. 10 avr. 2021 à 06:43, Sungpil Han ***@***.***> a
écrit :
… @nskoch <https://github.com/nskoch> ,
It's mainly due to an input of the key argument.
Or you can check if there're duplicates of time and concentration data for
a given subject.
It would be nice if you could provide minimal working example (MWE), and I
will sort out the problem for you.
Pil
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Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
Office: +33 49 106 5874
Mobile: +33 63 339 1765
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Use R2ADJ=0 option
나의 iPhone에서 보냄
… 2021. 4. 10. 23:57, Simon ***@***.***> 작성:
Hi
I work with simulated data, 2 groups of subjects (n=2x500) with 2 full
profiles by subject.
When I limit my dataset to 20 pk profiles, it runs bu I have to define the
slope manually which is not possible for 1000 subject.
My interest is on AUCall, Tmax and Cmax, I do not need slope. Is it
possible with the package ?
Best regards
Nicolas
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
Garanti
sans virus. www.avast.com
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<#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
Le sam. 10 avr. 2021 à 06:43, Sungpil Han ***@***.***> a
écrit :
> @nskoch <https://github.com/nskoch> ,
>
> It's mainly due to an input of the key argument.
> Or you can check if there're duplicates of time and concentration data for
> a given subject.
>
> It would be nice if you could provide minimal working example (MWE), and I
> will sort out the problem for you.
>
> Pil
>
> —
> You are receiving this because you were mentioned.
> Reply to this email directly, view it on GitHub
> <#1 (comment)>,
> or unsubscribe
> <https://github.com/notifications/unsubscribe-auth/AKBGW6HNGDKEDJSCC77TPX3TH7JNRANCNFSM4IXCTT7Q>
> .
>
--
Pharmacology & Pharmacokinetic Consultant
Professor of Medicine, University of Aix-Marseille
Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
Office: +33 49 106 5874
Mobile: +33 63 339 1765
—
You are receiving this because you are subscribed to this thread.
Reply to this email directly, view it on GitHub, or unsubscribe.
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나의 iPhone에서 보냄
2021. 4. 11. 06:57, Bae Kyun-Seop ***@***.***> 작성:
Use R2ADJ=0 option
나의 iPhone에서 보냄
2021. 4. 10. 23:57, Simon ***@***.***> 작성:
Hi
I work with simulated data, 2 groups of subjects (n=2x500) with 2 full
profiles by subject.
When I limit my dataset to 20 pk profiles, it runs bu I have to define the
slope manually which is not possible for 1000 subject.
My interest is on AUCall, Tmax and Cmax, I do not need slope. Is it
possible with the package ?
Best regards
Nicolas
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
Garanti
sans virus. www.avast.com
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
<#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
Le sam. 10 avr. 2021 à 06:43, Sungpil Han ***@***.***> a
écrit :
… @nskoch <https://github.com/nskoch> ,
It's mainly due to an input of the key argument.
Or you can check if there're duplicates of time and concentration data for
a given subject.
It would be nice if you could provide minimal working example (MWE), and I
will sort out the problem for you.
Pil
—
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Reply to this email directly, view it on GitHub
<#1 (comment)>,
or unsubscribe
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.
--
Pharmacology & Pharmacokinetic Consultant
Professor of Medicine, University of Aix-Marseille
Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
Office: +33 49 106 5874
Mobile: +33 63 339 1765
—
You are receiving this because you are subscribed to this thread.
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Hi
many thanks, it works fine.
My two groups received different dose, is it possible to take it into
account? In the examples, only one dose value is given.
Further each subject has 2 profiles, is it possible to compute PK
parameters for each profile?
I have created 2 ID for each subject (one for each profile) but that's not
elegant.
Best regards
Nicolas
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
Garanti
sans virus. www.avast.com
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
<#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
Le dim. 11 avr. 2021 à 00:24, Kyun-Seop Bae ***@***.***> a
écrit :
…
나의 iPhone에서 보냄
2021. 4. 11. 06:57, Bae Kyun-Seop ***@***.***> 작성:
Use R2ADJ=0 option
나의 iPhone에서 보냄
2021. 4. 10. 23:57, Simon ***@***.***> 작성:
Hi
I work with simulated data, 2 groups of subjects (n=2x500) with 2 full
profiles by subject.
When I limit my dataset to 20 pk profiles, it runs bu I have to define the
slope manually which is not possible for 1000 subject.
My interest is on AUCall, Tmax and Cmax, I do not need slope. Is it
possible with the package ?
Best regards
Nicolas
<
https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
Garanti
sans virus. www.avast.com
<
https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
<#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
Le sam. 10 avr. 2021 à 06:43, Sungpil Han ***@***.***> a
écrit :
> @nskoch <https://github.com/nskoch> ,
>
> It's mainly due to an input of the key argument.
> Or you can check if there're duplicates of time and concentration data
for
> a given subject.
>
> It would be nice if you could provide minimal working example (MWE), and
I
> will sort out the problem for you.
>
> Pil
>
> —
> You are receiving this because you were mentioned.
> Reply to this email directly, view it on GitHub
> <
#1 (comment)>,
> or unsubscribe
> <
https://github.com/notifications/unsubscribe-auth/AKBGW6HNGDKEDJSCC77TPX3TH7JNRANCNFSM4IXCTT7Q>
> .
>
--
Pharmacology & Pharmacokinetic Consultant
Professor of Medicine, University of Aix-Marseille
Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
Office: +33 49 106 5874
Mobile: +33 63 339 1765
—
You are receiving this because you are subscribed to this thread.
Reply to this email directly, view it on GitHub<
#1 (comment)>,
or unsubscribe<
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.
--
Pharmacology & Pharmacokinetic Consultant
Professor of Medicine, University of Aix-Marseille
Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
Office: +33 49 106 5874
Mobile: +33 63 339 1765
|
|
The necessary option is similar to the following;
...( , key=c(“ID”, “Period”), ...)
2021. 4. 11. 18:03, Simon ***@***.***> 작성:
Hi
many thanks, it works fine.
My two groups received different dose, is it possible to take it into
account? In the examples, only one dose value is given.
Further each subject has 2 profiles, is it possible to compute PK
parameters for each profile?
I have created 2 ID for each subject (one for each profile) but that's not
elegant.
Best regards
Nicolas
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
Garanti
sans virus. www.avast.com
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
<#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
Le dim. 11 avr. 2021 à 00:24, Kyun-Seop Bae ***@***.***> a
écrit :
…
나의 iPhone에서 보냄
2021. 4. 11. 06:57, Bae Kyun-Seop ***@***.***> 작성:
Use R2ADJ=0 option
나의 iPhone에서 보냄
2021. 4. 10. 23:57, Simon ***@***.***> 작성:
Hi
I work with simulated data, 2 groups of subjects (n=2x500) with 2 full
profiles by subject.
When I limit my dataset to 20 pk profiles, it runs bu I have to define the
slope manually which is not possible for 1000 subject.
My interest is on AUCall, Tmax and Cmax, I do not need slope. Is it
possible with the package ?
Best regards
Nicolas
<
https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
Garanti
sans virus. www.avast.com
<
https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
<#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
Le sam. 10 avr. 2021 à 06:43, Sungpil Han ***@***.***> a
écrit :
> @nskoch <https://github.com/nskoch> ,
>
> It's mainly due to an input of the key argument.
> Or you can check if there're duplicates of time and concentration data
for
> a given subject.
>
> It would be nice if you could provide minimal working example (MWE), and
I
> will sort out the problem for you.
>
> Pil
>
> —
> You are receiving this because you were mentioned.
> Reply to this email directly, view it on GitHub
> <
#1 (comment)>,
> or unsubscribe
> <
https://github.com/notifications/unsubscribe-auth/AKBGW6HNGDKEDJSCC77TPX3TH7JNRANCNFSM4IXCTT7Q>
> .
>
--
Pharmacology & Pharmacokinetic Consultant
Professor of Medicine, University of Aix-Marseille
Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
Office: +33 49 106 5874
Mobile: +33 63 339 1765
—
You are receiving this because you are subscribed to this thread.
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#1 (comment)>,
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.
--
Pharmacology & Pharmacokinetic Consultant
Professor of Medicine, University of Aix-Marseille
Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
Office: +33 49 106 5874
Mobile: +33 63 339 1765
—
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Many thanks
That’s fine
Nicolas
… Le 11 avr. 2021 à 11:43, Kyun-Seop Bae ***@***.***> a écrit :
The necessary option is similar to the following;
...( , key=c(“ID”, “Period”), ...)
2021. 4. 11. 18:03, Simon ***@***.***> 작성:
Hi
many thanks, it works fine.
My two groups received different dose, is it possible to take it into
account? In the examples, only one dose value is given.
Further each subject has 2 profiles, is it possible to compute PK
parameters for each profile?
I have created 2 ID for each subject (one for each profile) but that's not
elegant.
Best regards
Nicolas
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
Garanti
sans virus. www.avast.com
<https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
<#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
Le dim. 11 avr. 2021 à 00:24, Kyun-Seop Bae ***@***.***> a
écrit :
>
>
>
>
> 나의 iPhone에서 보냄
> 2021. 4. 11. 06:57, Bae Kyun-Seop ***@***.***> 작성:
>
>
> Use R2ADJ=0 option
>
>
>
>
> 나의 iPhone에서 보냄
> 2021. 4. 10. 23:57, Simon ***@***.***> 작성:
>
>
>
> Hi
>
> I work with simulated data, 2 groups of subjects (n=2x500) with 2 full
> profiles by subject.
> When I limit my dataset to 20 pk profiles, it runs bu I have to define the
> slope manually which is not possible for 1000 subject.
> My interest is on AUCall, Tmax and Cmax, I do not need slope. Is it
> possible with the package ?
>
> Best regards
> Nicolas
>
>
> <
> https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
>
> Garanti
> sans virus. www.avast.com
> <
> https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
>
> <#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
>
> Le sam. 10 avr. 2021 à 06:43, Sungpil Han ***@***.***> a
> écrit :
>
> > @nskoch <https://github.com/nskoch> ,
> >
> > It's mainly due to an input of the key argument.
> > Or you can check if there're duplicates of time and concentration data
> for
> > a given subject.
> >
> > It would be nice if you could provide minimal working example (MWE), and
> I
> > will sort out the problem for you.
> >
> > Pil
> >
> > —
> > You are receiving this because you were mentioned.
> > Reply to this email directly, view it on GitHub
> > <
> #1 (comment)>,
>
> > or unsubscribe
> > <
> https://github.com/notifications/unsubscribe-auth/AKBGW6HNGDKEDJSCC77TPX3TH7JNRANCNFSM4IXCTT7Q>
>
> > .
> >
>
>
> --
> Pharmacology & Pharmacokinetic Consultant
> Professor of Medicine, University of Aix-Marseille
> Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
> Office: +33 49 106 5874
> Mobile: +33 63 339 1765
>
> —
> You are receiving this because you are subscribed to this thread.
> Reply to this email directly, view it on GitHub<
> #1 (comment)>,
> or unsubscribe<
> https://github.com/notifications/unsubscribe-auth/ACKQA4RCXC6RDVS4RYCAQ3TTIBROHANCNFSM4IXCTT7Q>.
>
>
> —
> You are receiving this because you were mentioned.
> Reply to this email directly, view it on GitHub
> <#1 (comment)>,
> or unsubscribe
> <https://github.com/notifications/unsubscribe-auth/AKBGW6G3MTGSREMCMA2QARTTIDF3JANCNFSM4IXCTT7Q>
> .
>
--
Pharmacology & Pharmacokinetic Consultant
Professor of Medicine, University of Aix-Marseille
Head of the Department of Clinical Pharmacology, Ste Marguerite Hospital
Office: +33 49 106 5874
Mobile: +33 63 339 1765
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Hi,
I've been testing the NonCompart package for some time and I've found some datasets which the package function fails or prints a message somewhat strange.
I'll be reporting one issue at time. So, I've submitted a dataset where I'm not being able to use neither sNCA nor tblNCA.
fail1.xlsx
It just prints the message below and fails
Thank you.
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