About tgthighres

[995884191]

Hello.
In the get embedding.py: "parser.add_argument('--tgthighres', type=str, default='t4', help='the targeted high resolution (start with t) or the fold change of the high resolution (start with f), or the addtion (start with a) of the high resoultion. only valid for input_type=singlecell')"

“the fold change of the high resolution (start with f)”Does this mean that in f mode, I can input the fold change of single-cell RNA expression levels, such as +2 or -2, to indicate the upregulation or downregulation values of genes compared to the control group?

Looking forward to your reply, thank you！

[WhirlFirst]

Hi, you can input the positive fold change value. As for the negative value, We didn't pre-train the model to do the downregulation so I think it may not work very well in this case.