diff --git a/internal/node/localtxmonitor.go b/internal/node/localtxmonitor.go
new file mode 100644
index 0000000..44e732c
--- /dev/null
+++ b/internal/node/localtxmonitor.go
@@ -0,0 +1,35 @@
+// Copyright 2024 Blink Labs Software
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+package node
+
+import (
+	"time"
+
+	"github.com/blinklabs-io/gouroboros/protocol/localtxmonitor"
+
+	"github.com/blinklabs-io/cardano-node-api/internal/config"
+)
+
+func buildLocalTxMonitorConfig() localtxmonitor.Config {
+	cfg := config.GetConfig()
+	return localtxmonitor.NewConfig(
+		localtxmonitor.WithAcquireTimeout(
+			time.Duration(cfg.Node.Timeout) * time.Second,
+		),
+		localtxmonitor.WithQueryTimeout(
+			time.Duration(cfg.Node.Timeout) * time.Second,
+		),
+	)
+}
diff --git a/internal/node/node.go b/internal/node/node.go
index 91be4ae..f63909c 100644
--- a/internal/node/node.go
+++ b/internal/node/node.go
@@ -31,6 +31,7 @@ func GetConnection() (*ouroboros.Connection, error) {
 		ouroboros.WithNodeToNode(false),
 		ouroboros.WithKeepAlive(true),
 		ouroboros.WithChainSyncConfig(buildChainSyncConfig()),
+		ouroboros.WithLocalTxMonitorConfig(buildLocalTxMonitorConfig()),
 		ouroboros.WithLocalTxSubmissionConfig(buildLocalTxSubmissionConfig()),
 	)
 	if err != nil {