From c7a5c9ff7666c7fa0fce2181f5ed39701aba1434 Mon Sep 17 00:00:00 2001 From: bvbellomo <32344264+bvbellomo@users.noreply.github.com> Date: Sun, 13 Oct 2024 19:51:34 -0400 Subject: [PATCH] update --- research.html | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/research.html b/research.html index b9e5d4d..b508da7 100644 --- a/research.html +++ b/research.html @@ -40,7 +40,7 @@

Relevance to Health and Disease

My Unpublished Research

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It is difficult to write a web page about unpublished research, as a web page is publication, and while I want to advocate my ideas, I don't want to share anything that could hurt my career. +

It is difficult to write a web page about unpublished research, as a web page is publication. I want to advocate my ideas, but I don't want to share anything that could hurt my career. Much more details about what I've done will appear here after my next article is published.

As a Computer Scientist, I am working on quantifying and predicting the effects of miRNA targeting. We know the RISC binds to mRNA with sequences complementary to nucleotides 2-8 of the miRNA. However, not all locations with complements are biologically relevant, and in animals, having a mismatch or gap is possible. When a target is confirmed, the miRNA might slightly decrease protein expression, or completely eliminate it, or even an increase protein expression.