diff --git a/packages/react/src/components/ComboBox/ComboBox-test.js b/packages/react/src/components/ComboBox/ComboBox-test.js
index c2d07c34703e..1fb29ed4eead 100644
--- a/packages/react/src/components/ComboBox/ComboBox-test.js
+++ b/packages/react/src/components/ComboBox/ComboBox-test.js
@@ -423,4 +423,69 @@ describe('ComboBox', () => {
       );
     });
   });
+  describe('ComboBox autocomplete', () => {
+    const items = [
+      { id: 'option-1', text: 'Option 1' },
+      { id: 'option-2', text: 'Option 2' },
+      { id: 'option-3', text: 'Option 3' },
+    ];
+
+    const mockProps = {
+      id: 'test-combobox',
+      items,
+      itemToString: (item) => (item ? item.text : ''),
+      onChange: jest.fn(),
+    };
+
+    it('should respect autocomplete prop', async () => {
+      render(<ComboBox {...mockProps} autocomplete />);
+      await waitForPosition();
+      const inputNode = findInputNode();
+      expect(inputNode).toHaveAttribute('autocomplete');
+    });
+    it('should use autocompleteCustomFilter when autocomplete prop is true', async () => {
+      render(<ComboBox {...mockProps} autocomplete />);
+
+      // Open the dropdown
+      const input = screen.getByRole('combobox');
+      fireEvent.click(input);
+
+      // Type 'op' which should match all options
+      await userEvent.type(input, 'op');
+      expect(screen.getAllByRole('option')).toHaveLength(3);
+
+      // Type 'opt' which should still match all options
+      await userEvent.type(input, 't');
+      expect(screen.getAllByRole('option')).toHaveLength(3);
+
+      // Type 'opti' which should match only 'Option 1'
+      await userEvent.type(input, 'i');
+      expect(screen.getAllByRole('option')).toHaveLength(3);
+      expect(screen.getByText('Option 1')).toBeInTheDocument();
+    });
+
+    it('should use default filter when autocomplete prop is false', async () => {
+      render(<ComboBox {...mockProps} />);
+
+      // Open the dropdown
+      const input = screen.getByRole('combobox');
+      fireEvent.click(input);
+
+      // Type 'op' which should match all options
+      await userEvent.type(input, 'op');
+      expect(screen.getAllByRole('option')).toHaveLength(3);
+
+      // Type 'opt' which should still match all options
+      await userEvent.type(input, 't');
+      expect(screen.getAllByRole('option')).toHaveLength(3);
+
+      // Type 'opti' which should still match all options
+      await userEvent.type(input, 'i');
+      expect(screen.getAllByRole('option')).toHaveLength(3);
+
+      // Type 'option' which should still match all options
+      await userEvent.type(input, 'on');
+      expect(screen.getAllByRole('option')).toHaveLength(3);
+    });
+  });
 });
diff --git a/packages/react/src/components/ComboBox/ComboBox.stories.js b/packages/react/src/components/ComboBox/ComboBox.stories.js
index 916f7777baae..7136b1e9c7b6 100644
--- a/packages/react/src/components/ComboBox/ComboBox.stories.js
+++ b/packages/react/src/components/ComboBox/ComboBox.stories.js
@@ -11,6 +11,7 @@ import { WithLayer } from '../../../.storybook/templates/WithLayer';
 
 import ComboBox from '../ComboBox';
 import mdx from './ComboBox.mdx';
+import { on } from 'process';
 
 const items = [
   {
@@ -92,6 +93,21 @@ export const AllowCustomValue = (args) => {
     </div>
   );
 };
+export const AutocompleteWithTypeahead = (args) => {
+  return (
+    <div style={{ width: 300 }}>
+      <ComboBox
+        allowCustomValue
+        autocomplete
+        onChange={args.onChange}
+        id="carbon-combobox"
+        items={['Apple', 'Orange', 'Banana', 'Pineapple', 'Raspberry', 'Lime']}
+        titleText="ComboBox title"
+        helperText="Combobox helper text"
+      />
+    </div>
+  );
+};
 export const ExperimentalAutoAlign = () => (
   <div style={{ width: 400 }}>
     <div style={{ height: 300 }}></div>
@@ -112,6 +128,10 @@ AllowCustomValue.argTypes = {
   onChange: { action: 'onChange' },
 };
 
+AutocompleteWithTypeahead.argTypes = {
+  onChange: { action: 'onChange' },
+};
+
 export const _WithLayer = () => (
   <WithLayer>
     {(layer) => (
diff --git a/packages/react/src/components/ComboBox/ComboBox.tsx b/packages/react/src/components/ComboBox/ComboBox.tsx
index 9fdf344dd3e5..10cb9c11df74 100644
--- a/packages/react/src/components/ComboBox/ComboBox.tsx
+++ b/packages/react/src/components/ComboBox/ComboBox.tsx
@@ -159,6 +159,10 @@ export interface ComboBoxProps<ItemType>
    */
   autoAlign?: boolean;
 
+  /**
+   * **Experimental**: will enable autcomplete and typeahead for the input field
+   */
+  autocomplete?: boolean;
   /**
    * An optional className to add to the container node
    */
@@ -323,6 +327,7 @@ const ComboBox = forwardRef(
       ['aria-label']: ariaLabel = 'Choose an item',
       ariaLabel: deprecatedAriaLabel,
       autoAlign = false,
+      autocomplete = false,
       className: containerClassName,
       direction = 'bottom',
       disabled = false,
@@ -406,14 +411,32 @@ const ComboBox = forwardRef(
         })
       );
     }
+    const autocompleteCustomFilter = (menu) => {
+      if (
+        !menu ||
+        typeof menu.item !== 'string' ||
+        typeof menu.inputValue !== 'string'
+      ) {
+        return false;
+      }
+      const item = menu.item.toLowerCase();
+      const input = menu.inputValue.toLowerCase();
+
+      if (input.length > item.length) {
+        return false;
+      }
 
+      return input.split('').every((char, index) => item[index] === char);
+    };
     const filterItems = (
       items: ItemType[],
       itemToString: ItemToStringHandler<ItemType>,
       inputValue: string | null
     ) =>
       items.filter((item) =>
-        shouldFilterItem
+        autocomplete
+          ? autocompleteCustomFilter({ item: itemToString(item), inputValue })
+          : shouldFilterItem
           ? shouldFilterItem({
               item,
               itemToString,
@@ -662,7 +685,13 @@ const ComboBox = forwardRef(
           'aria-label': deprecatedAriaLabel || ariaLabel,
           ref: autoAlign ? refs.setFloating : null,
         }),
-      [autoAlign, deprecatedAriaLabel, ariaLabel]
+      [
+        getMenuProps,
+        deprecatedAriaLabel,
+        ariaLabel,
+        autoAlign,
+        refs.setFloating,
+      ]
     );
 
     return (
@@ -884,6 +913,11 @@ ComboBox.propTypes = {
    */
   autoAlign: PropTypes.bool,
 
+  /**
+   * **Experimental**: will enable autcomplete and typeahead for the input field
+   */
+  autocomplete: PropTypes.bool,
+
   /**
    * An optional className to add to the container node
    */
diff --git a/packages/react/src/components/ListBox/test-helpers.js b/packages/react/src/components/ListBox/test-helpers.js
index 4f83ea7966a6..e0c55700399e 100644
--- a/packages/react/src/components/ListBox/test-helpers.js
+++ b/packages/react/src/components/ListBox/test-helpers.js
@@ -7,7 +7,7 @@
 
 const prefix = 'cds';
 import userEvent from '@testing-library/user-event';
-import { act } from 'react';
+import { act } from '@testing-library/react';
 
 // Finding nodes in a ListBox
 export const findListBoxNode = () => {