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hb.txt
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hb.txt
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[cH1:1]1:[c:2](-[CH2:7]-[CH2:8]-[NH2:9]):[c:3]:[c:4]:[c:5]:[c:6]:1.[#6:11]-[CH1;R0:10]=[OD1]>>[c:1]12:[c:2](-[CH2:7]-[CH2:8]-[NH1:9]-[C:10]-2(-[#6:11])):[c:3]:[c:4]:[c:5]:[c:6]:1
[c;r6:1](-[NH1;$(N-[#6]):2]):[c;r6:3](-[NH2:4]).[#6:6]-[C;R0:5](=[OD1])-[#8;H1,$(O-[CH3])]>>[c:3]2:[c:1]:[n:2]:[c:5](-[#6:6]):[n:4]2
[c;r6:1](-[NH1;$(N-[#6]):2]):[c;r6:3](-[NH2:4]).[#6:6]-[CH1;R0:5](=[OD1])>>[c:3]2:[c:1]:[n:2]:[c:5](-[#6:6]):[n:4]2
[c;r6:1](-[SH1:2]):[c;r6:3](-[NH2:4]).[#6:6]-[CH1;R0:5](=[OD1])>>[c:3]2:[c:1]:[s:2]:[c:5](-[#6:6]):[n:4]2
[c:1](-[OH1;$(Oc1ccccc1):2]):[c;r6:3](-[NH2:4]).[c:6]-[CH1;R0:5](=[OD1])>>[c:3]2:[c:1]:[o:2]:[c:5](-[c:6]):[n:4]2
[c;r6:1](-[OH1:2]):[c;r6:3](-[NH2:4]).[#6:6]-[C;R0:5](=[OD1])-[OH1]>>[c:3]2:[c:1]:[o:2]:[c:5](-[#6:6]):[n:4]2
[#6:6]-[C;R0:1](=[OD1])-[CH1;R0:5](-[#6:7])-[*;#17,#35,#53].[NH2:2]-[C:3]=[SD1:4]>>[c:1]2(-[#6:6]):[n:2]:[c:3]:[s:4][c:5]([#6:7]):2
[c:1](-[C;$(C-c1ccccc1):2](=[OD1:3])-[OH1]):[c:4](-[NH2:5]).[N;!H0;!$(N-N);!$(N-C=N);!$(N(-C=O)-C=O):6]-[C;H1,$(C-[#6]):7]=[OD1]>>[c:4]2:[c:1]-[C:2](=[O:3])-[N:6]-[C:7]=[N:5]-2
[CH0;$(C-[#6]):1]#[NH0:2]>>[C:1]1=[N:2]-N-N=N-1
[CH0;$(C-[#6]):1]#[NH0:2].[C;A;!$(C=O):3]-[*;#17,#35,#53]>>[C:1]1=[N:2]-N(-[C:3])-N=N-1
[CH0;$(C-[#6]):1]#[NH0:2].[C;A;!$(C=O):3]-[*;#17,#35,#53]>>[C:1]1=[N:2]-N=N-N-1(-[C:3])
[CH0;$(C-[#6]):1]#[CH1:2].[C;H1,H2;A;!$(C=O):3]-[*;#17,#35,#53,OH1]>>[C:1]1=[C:2]-N(-[C:3])-N=N-1
[CH0;$(C-[#6]):1]#[CH1:2].[C;H1,H2;A;!$(C=O):3]-[*;#17,#35,#53,OH1]>>[C:1]1=[C:2]-N=NN(-[C:3])-1
[CH0;$(C-[#6]):1]#[CH0;$(C-[#6]):2].[C;H1,H2;A;!$(C=O):3]-[*;#17,#35,#53,OH1]>>[C:1]1=[C:2]-N=NN(-[C:3])-1
[CH0;$(C-[#6]):1]#[NH0:2].[NH2:3]-[NH1:4]-[CH0;$(C-[#6]);R0:5]=[OD1]>>[N:2]1-[C:1]=[N:3]-[N:4]-[C:5]=1
[CH0;$(C-[#6]):1]#[NH0:2].[CH0;$(C-[#6]);R0:5](=[OD1])-[#8;H1,$(O-[CH3]),$(O-[CH2]-[CH3])]>>[N:2]1-[C:1]=N-N-[C:5]=1
[c:1](-[C;$(C-c1ccccc1):2](=[OD1:3])-[CH3:4]):[c:5](-[OH1:6]).[C;$(C1-[CH2]-[CH2]-[N,C]-[CH2]-[CH2]-1):7](=[OD1])>>[O:6]1-[c:5]:[c:1]-[C:2](=[OD1:3])-[C:4]-[C:7]-1
[c;r6:1](-[C;$(C=O):6]-[OH1]):[c;r6:2]-[C;H1,$(C-C):3]=[OD1].[NH2:4]-[NH1;$(N-[#6]);!$(NC=[O,S,N]):5]>>[c:1]1:[c:2]-[C:3]=[N:4]-[N:5]-[C:6]-1
[C;$(C-c1ccccc1):1](=[OD1])-[C;D3;$(C-c1ccccc1):2]~[O;D1,H1].[CH1;$(C-c):3]=[OD1]>>[C:1]1-N=[C:3]-[NH1]-[C:2]=1
[NH1;$(N-c1ccccc1):1](-[NH2])-[c:5]:[cH1:4].[C;$(C([#6])[#6]):2](=[OD1])-[CH2;$(C([#6])[#6]);!$(C(C=O)C=O):3]>>[C:5]1-[N:1]-[C:2]=[C:3]-[C:4]:1
[NH2;$(N-c1ccccc1):1]-[c:2]:[c:3]-[CH1:4]=[OD1].[C;$(C([#6])[#6]):6](=[OD1])-[CH2;$(C([#6])[#6]);!$(C(C=O)C=O):5]>>[N:1]1-[c:2]:[c:3]-[C:4]=[C:5]-[C:6]:1
[*;Br,I;$(*c1ccccc1)]-[c:1]:[c:2]-[OH1:3].[CH1:5]#[C;$(C-[#6]):4]>>[c:1]1:[c:2]-[O:3]-[C:4]=[C:5]-1
[*;Br,I;$(*c1ccccc1)]-[c:1]:[c:2]-[SD2:3]-[CH3].[CH1:5]#[C;$(C-[#6]):4]>>[c:1]1:[c:2]-[S:3]-[C:4]=[C:5]-1
[*;Br,I;$(*c1ccccc1)]-[c:1]:[c:2]-[NH2:3].[CH1:5]#[C;$(C-[#6]):4]>>[c:1]1:[c:2]-[N:3]-[C:4]=[C:5]-1
[#6:6][C:5]#[#7;D1:4].[#6:1][C:2](=[OD1:3])[OH1]>>[#6:6][c:5]1[n:4][o:3][c:2]([#6:1])n1
[#6;$([#6]~[#6]);!$([#6]=O):2][#8;H1:3].[Cl,Br,I][#6;H2;$([#6]~[#6]):4]>>[CH2:4][O:3][#6:2]
[#6;H0;D3;$([#6](~[#6])~[#6]):1]B(O)O.[#6;H0;D3;$([#6](~[#6])~[#6]):2][Cl,Br,I]>>[#6:2][#6:1]
[c;H1:3]1:[c:4]:[c:5]:[c;H1:6]:[c:7]2:[nH:8]:[c:9]:[c;H1:1]:[c:2]:1:2.O=[C:10]1[#6;H2:11][#6;H2:12][N:13][#6;H2:14][#6;H2:15]1>>[#6;H2:12]3[#6;H1:11]=[C:10]([c:1]1:[c:9]:[n:8]:[c:7]2:[c:6]:[c:5]:[c:4]:[c:3]:[c:2]:1:2)[#6;H2:15][#6;H2:14][N:13]3
[C;H1&$(C([#6])[#6]),H2&$(C[#6]):1][OH1].[NH1;$(N(C=O)C=O):2]>>[C:1][N:2]
[C;H1&$(C([#6])[#6]),H2&$(C[#6]):1][OH1].[OH1;$(Oc1ccccc1):2]>>[C:1][O:2]
[C;H1&$(C([#6])[#6]),H2&$(C[#6]):1][OH1].[NH1;$(N([#6])S(=O)=O):2]>>[C:1][N:2]
[C;H1&$(C([#6])[#6]),H2&$(C[#6]):1][OH1].[#7H1:2]1~[#7:3]~[#7:4]~[#7:5]~[#6:6]~1>>[C:1][#7:2]1:[#7:3]:[#7:4]:[#7:5]:[#6:6]:1
[C;H1&$(C([#6])[#6]),H2&$(C[#6]):1][OH1].[#7H1:2]1~[#7:3]~[#7:4]~[#7:5]~[#6:6]~1>>[#7H0:2]1:[#7:3]:[#7H0:4]([C:1]):[#7:5]:[#6:6]:1
[C;H1&$(C([#6])[#6]),H2&$(C[#6]):1][OH1].[#7:2]1~[#7:3]~[#7H1:4]~[#7:5]~[#6:6]~1>>[C:1][#7H0:2]1:[#7:3]:[#7H0:4]:[#7:5]:[#6:6]:1
[C;H1&$(C([#6])[#6]),H2&$(C[#6]):1][OH1].[#7:2]1~[#7:3]~[#7H1:4]~[#7:5]~[#6:6]~1>>[#7:2]1:[#7:3]:[#7:4]([C:1]):[#7:5]:[#6:6]:1
[#6;$(C=C-[#6]),$(c:c):1][Br,I].[Cl,Br,I][c:2]>>[c:2][#6:1]
[#6:1][C:2]#[#7;D1].[Cl,Br,I][#6;$([#6]~[#6]);!$([#6]([Cl,Br,I])[Cl,Br,I]);!$([#6]=O):3]>>[#6:1][C:2](=O)[#6:3]
[#6:1][C;H1,$([C]([#6])[#6]):2]=[OD1:3].[Cl,Br,I][#6;$([#6]~[#6]);!$([#6]([Cl,Br,I])[Cl,Br,I]);!$([#6]=O):4]>>[C:1][#6:2]([OH1:3])[#6:4]
[S;$(S(=O)(=O)[C,N]):1][Cl].[N;$(NC);!$(N=*);!$([N-]);!$(N#*);!$([ND3]);!$([ND4]);!$(N[c,O]);!$(N[C,S]=[S,O,N]):2]>>[S:1][N+0:2]
[c:1]B(O)O.[#7H1;+0;r5,r6;!$(n[#6]=[O,S,N]);!$(n~n~n);!$(n~n~c~n);!$(n~c~n~n):2]>>[c:1][n:2]
[#6:3]-[C;H1,$([CH0](-[#6])[#6]);!$(CC=O):1]=[OD1].[Cl,Br,I][C;H2;$(C-[#6]);!$(CC[I,Br]);!$(CCO[CH3]):2]>>[C:3][C:1]=[C:2]
[Cl,Br,I][c;$(c1:[c,n]:[c,n]:[c,n]:[c,n]:[c,n]:1):1].[N;$(NC)&!$(N=*)&!$([N-])&!$(N#*)&!$([ND3])&!$([ND4])&!$(N[c,O])&!$(N[C,S]=[S,O,N]),H2&$(Nc1:[c,n]:[c,n]:[c,n]:[c,n]:[c,n]:1):2]>>[c:1][N:2]
[C;$(C([#6])[#6;!$([#6]Br)]):4](=[OD1])[CH;$(C([#6])[#6]):5]Br.[#7;H2:3][C;$(C(=N)(N)[c,#7]):2]=[#7;H1;D1:1]>>[C:4]1=[CH0:5][NH:3][C:2]=[N:1]1
[c;$(c1[c;$(c[C,S,N](=[OD1])[*;R0;!OH1])]cccc1):1][C;$(C(=O)[O;H1])].[c;$(c1aaccc1):2][Cl,Br,I]>>[c:1][c:2]
[c;!$(c1ccccc1);$(c1[n,c]c[n,c]c[n,c]1):1][Cl,F].[N;$(NC);!$(N=*);!$([N-]);!$(N#*);!$([ND3]);!$([ND4]);!$(N[c,O]);!$(N[C,S]=[S,O,N]):2]>>[c:1][N:2]
[c;$(c1c(N(~O)~O)cccc1):1][Cl,F].[N;$(NC);!$(N=*);!$([N-]);!$(N#*);!$([ND3]);!$([ND4]);!$(N[c,O]);!$(N[C,S]=[S,O,N]):2]>>[c:1][N:2]
[c;$(c1ccc(N(~O)~O)cc1):1][Cl,F].[N;$(NC);!$(N=*);!$([N-]);!$(N#*);!$([ND3]);!$([ND4]);!$(N[c,O]);!$(N[C,S]=[S,O,N]):2]>>[c:1][N:2]
[N;$(N-[#6]):3]=[C;$(C=O):1].[N;$(N[#6]);!$(N=*);!$([N-]);!$(N#*);!$([ND3]);!$([ND4]);!$(N[O,N]);!$(N[C,S]=[S,O,N]):2]>>[N:3]-[C:1]-[N+0:2]
[N;$(N-[#6]):3]=[C;$(C=S):1].[N;$(N[#6]);!$(N=*);!$([N-]);!$(N#*);!$([ND3]);!$([ND4]);!$(N[O,N]);!$(N[C,S]=[S,O,N]):2]>>[N:3]-[C:1]-[N+0:2]
[$(C([CH2,CH3])),CH:10](=[O:11])-[NH+0:9]-[C$(C(N)(C)(C)(C)),C$([CH](N)(C)(C)),C$([CH2](N)(C)):8]-[C$(C(c)(C)(C)(C)),C$([CH](c)(C)(C)),C$([CH2](c)(C)):7]-[c:6]1[cH:1][c:2][c:3][c:4][c:5]1>>[C:10]-1=[N+0:9]-[C:8]-[C:7]-[c:6]2[c:5][c:4][c:3][c:2][c:1]-12
[$(C([CH2,CH3])),CH:10](=[O:11])-[NH+0:9]-[C$([CH](N)(C)(C)),C$([CH2](N)(C)):8]-[C$([C](c)(C)(C)),C$([CH](c)(C)):7]([O$(OC),OH])-[c:6]1[cH:1][c:2][c:3][c:4][c:5]1>>[c:10]-1[n:9][c:8][c:7][c:6]2[c:5][c:4][c:3][c:2][c:1]-12
[NH3+,NH2]-[C$(C(N)(C)(C)(C)),C$([CH](N)(C)(C)),C$([CH2](N)(C)):8]-[C$(C(c)(C)(C)(C)),C$([CH](c)(C)(C)),C$([CH2](c)(C)):7]-[c:6]1[c:1][c:2][nH:3][cH:5]1.[CH:10](-[CX4:12])=[O:11]>>[c,C:12]-[CH:10]-1-[N]-[C:8]-[C:7]-[c:6]2[c:1][c:2][nH:3][c:5]-12
[NH2,NH3+1:8]-[c:5]1[cH:4][c:3][c:2][c:1][c:6]1.[Br:18][C$([CH2](C)(Br)),C$([CH](C)(C)(Br)):17]-[C:15](=[O:16])-[c:10]1[c:11][c:12][c:13][c:14][c:9]1>>[c:13]1[c:12][c:11][c:10]([c:9][c:14]1)-[c:15]1[c:17][c:4]2[c:3][c:2][c:1][c:6][c:5]2[nH+0:8]1
[Cl:1][CH2:2]-[C$([CH](C)),C$(C(C)(C)):3]=[O:4].[OH:12]-[c:11]1[c:6][c:7][c:8][c:9][c:10]1-[CH:13]=[O:14]>>[C:3](=[O:4])-[c:2]1[c:13][c:10]2[c:9][c:8][c:7][c:6][c:11]2[o:12]1
[NH2,NH3+]-[C$([CX4](N)([c,C])([c,C])([c,C])),C$([CH](N)([c,C])([c,C])),C$([CH2](N)([c,C])),C$([CH3](N)):2].[NH2:12]-[c:7]1[c:6][c:5][c:4][c:3][c:8]1-[C:9](-[OH,O-:11])=[O:10]>>[C:2]-[n+0]-1[c:13][n:12][c:7]2[c:6][c:5][c:4][c:3][c:8]2[c:9]-1=[O:10]
[N$([NH2]([CX4])),N$([NH3+1]([CX4])):1].[O:5]-[C$([CH]([CX4])(C)(O)),C$([CH2]([CX4])(O)):3][C$(C([CX4])(=O)([CX4])),C$([CH]([CX4])(=O)):4]=[O:6]>[O:15]=[C:9]-1-[CH2:10]-[CH2:11]-[CH2:12]-[CH2:13]-[CH2:14]-1>[c:4]1[c:3][n+0:1][c:10]2-[C:11]-[C:12]-[C:13]-[C:14]-[c:9]12
[C$(C(=O)([CX4])([CX4])),C$([CH](=O)([CX4])):2](=[O:6])-[C$([CH]([CX4])),C$([CH2]):3]-[C$(C(=O)([CX4])([CX4])),C$([CH](=O)([CX4])):4]=[O:7].[NH2:8]-[C:9](=[O:10])-[CH2:11][C:12]#[N:13]>>[OH:10]-[c:9]1[n:8][c:4][c:3][c:2][c:11]1[C:12]#[N:13]
[C$(C(#C)([CX4])):2]#[C$(C(#C)([CX4])):1].[N$(N(~N)([CX4])):5]~[N]~[N]>>[c:2]1[c:1][n:5][n][n]1
[C$(C(=C)([CX4])):2]=[C$(C(=C)([CX4])):1].[N$(N(~N)([CX4])):5]~[N]~[N]>>[C:2]1[C:1][N:5][N]=[N]1
[C$(C(=C)([CX4,OX2,NX3])([CX4,OX2,NX3])),C$([CH](=C)([CX4,OX2,NX3])),C$([CH2](=C)):1]=[C$(C(=C)([CX4,OX2,NX3])([CX4,OX2,NX3])),C$([CH](=C)([CX4,OX2,NX3])),C$([CH2](=C)):2].[C$(C(=C)([CX4,OX2,NX3])([CX4,OX2,NX3])),C$([CH](=C)([CX4,OX2,NX3])),C$([CH2](=C)):3]=[C$([C](=C)(C)([CX4,OX2,NX3])),C$([CH](=C)(C)):4]-[C$([C](=C)(C)([CX4,OX2,NX3])),C$([CH](=C)(C)):5]=[C$(C(=C)([CX4,OX2,NX3])([CX4,OX2,NX3])),C$([CH](=C)([CX4,OX2,NX3])),C$([CH2](=C)):6]>>[C:1]1[C:2][C:3][C:4]=[C:5][C:6]1
[C$(C(#C)([CX4,OX2,NX3])),C$([CH](#C)):1]#[C$(C(#C)([CX4,OX2,NX3])),C$([CH](#C)):2].[C$(C(=C)([CX4,OX2,NX3])([CX4,OX2,NX3])),C$([CH](=C)([CX4,OX2,NX3])),C$([CH2](=C)):3]=[C$([C](=C)(C)([CX4,OX2,NX3])),C$([CH](=C)(C)):4]-[C$([C](=C)(C)([CX4,OX2,NX3])),C$([CH](=C)(C)):5]=[C$(C(=C)([CX4,OX2,NX3])([CX4,OX2,NX3])),C$([CH](=C)([CX4,OX2,NX3])),C$([CH2](=C)):6]>>[C:1]1=[C:2][C:3][C:4]=[C:5][C:6]1
[NH2,NH3+:3]-[N$([NH](N)([CX4])):2].[C$([CH](C)(C)([CX4])),C$([CH2](C)(C)):6](-[C$(C(=O)(C)([CX4])),C$([CH](=O)(C)):5]=[O:9])-[C$(C(=O)(C)([CX4])),C$([CH](=O)(C)):7]=[O:10]>>[c:7]1[n:3][n:2][c:5][c:6]1
[C$(C(=O)(C)([CX4])),C$(C[H](=O)(C)):1](=[O:2])-[$([CH](C)(C)([CX4])),$([CH2](C)(C)):3]-[$([CH](C)(C)([CX4])),$([CH2](C)(C)):4]-[C$(C(=O)(C)([CX4])),C$(C[H](=O)(C)):5]=[O:6].[N$([NH2,NH3+1]([CX4])):7]>>[c:5]1[c:4][c:3][c:1][n+0:7]1
[CH:7](=[O:8])-[c:1]1[c:2][c:3][c:4][c:5][c:6]1.[O:24]=[C:23](-[C:22](=[O:25])-[c:15]1[c:10][c:11][c:12][c:13][c:14]1)-[c:20]1[c:21][c:16][c:17][c:18][c:19]1>[NH4].[O-]C(=O)C>[nH:27]-1[c:7]([n:26][c:23]([c:22]-1[c:15]1[c:10][c:11][c:12][c:13][c:14]1)-[c:20]1[c:21][c:16][c:17][c:18][c:19]1)-[c:1]1[c:2][c:3][c:4][c:5][c:6]1
[OH:7]-[c:6]1[cH:1][c:2][c:3][c:4][c:5]1.[O$(O(C)([CX4])):12]-[C:11](=[O:15])-[C$([CH](C)(C)([CX4])),C$([CH2](C)(C)):10]-[C:8]=[O:16]>>[C:8]-1=[C:10]-[C:11](=[O:15])-[O]-[c:6]2[c:5][c:4][c:3][c:2][c:1]-12
[O$(O(C)([CX4])):8][C:7](=[O:9])[CH:6][C:5][C:4][C:3][C:2]([O$(O(C)([CX4])):10])=[O:1]>>[O:8][C:7](=[O:9])[C:6]1[C:5][C:4][C:3][C:2]1=[O:1]
[O$(O(C)([CX4])):8][C:7](=[O:9])[CH:6][C:5][C:11][C:4][C:3][C:2]([O$(O(C)([CX4])):10])=[O:1]>>[O:8][C:7](=[O:9])[C:6]1[C:5][C:11][C:4][C:3][C:2]1=[O:1]
[Cl:9][C:7](=[O:8])-[c:3]1[c:2][c:1][c:6][c:5][c:4]1.[C$([CH2](C)([CX4])),C$([CH3](C)):18]-[C:16](=[O:17])-[c:14]1[c:13][c:12][c:11][c:10][c:15]1-[OH:19]>>[O:17]=[C:16]-1-[C:18]=[C:7](-[O:8]-[c:15]2[c:10][c:11][c:12][c:13][c:14]-12)-[c:3]1[c:2][c:1][c:6][c:5][c:4]1
[C$(C(C)(=O)([CX4,OX2&H0])),C$(C(C)(#N)),N$([N+1](C)(=O)([O-1])):1][C$([CH]([C,N])([C,N])([CX4])),C$([CH2]([C,N])([C,N])):2][C$(C(C)(=O)([CX4,OX2&H0])),C$(C(C)(#N)),N$([N+1](C)(=O)([O-1])):3].[C$(C(C)(#N)),C$(C(C)([CX4,OX2&H0])([CX4,OX2&H0])([OX2&H0])),C$([CH](C)([CX4,OX2&H0])([OX2&H0])),C$([CH2](C)([OX2&H0])),C$(C(C)(=O)([OX2&H0])):6][CH:5]=[C$(C(=C)([CX4])([CX4])),C$([CH](=C)([CX4])),C$([CH2](=C)):4]>>[C:6][C:5][C:4][C:2]([C:1])[C:3]
[C$([C](O)([CX4])([CX4])([CX4])),C$([CH](O)([CX4])([CX4])),C$([CH2](O)([CX4])):4]-[O:3]-[C$(C(=O)([CX4])),C$([CH](=O)):2]=[O:5].[C$([CH](C)([CX4])([CX4])),C$([CH2](C)([CX4])),C$([CH3](C)):7]-[C$(C(=O)([CX4])),C$([CH](=O)):8]=[O:9]>>[C:7](-[C:2]=[O:5])-[C:8]=[O:9]
[Cl,OH,O-:3][C$(C(=O)([CX4,c])),C$([CH](=O)):2]=[O:4].[O$([OH]([CX4,c])),O$([OH]([CX4,c])([CX4,c])),S$([SH]([CX4,c])),S$([SH]([CX4,c])([CX4,c])):6]>>[*:6]-[C:2]=[O:4]
[C$(C(=O)([CX4,c])([CX4,c])),C$([CH](=O)([CX4,c])):1]=[O:2].[N$([NH2,NH3+1]([CX4,c])),N$([NH]([CX4,c])([CX4,c])):3]>>[N+0:3][C:1]
[Br:1][c$(c(Br)),n$(n(Br)),o$(o(Br)),C$([CH](Br)(=C)):2].[C$(C(B)([CX4])([CX4])([CX4])),C$([CH](B)([CX4])([CX4])),C$([CH2](B)([CX4])),C$([CH2](B)),C$(C(B)(=C)),c$(c(B)),o$(o(B)),n$(n(B)):3][B$(B([C,c,n,o])([OH,$(OC)])([OH,$(OC)])),B$([B-1]([C,c,n,o])(N)([OH,$(OC)])([OH,$(OC)])):4]>>[C,c,n,o:2][C,c,n,o:3]
[Br,I:1][C$(C([Br,I])([CX4])([CX4])([CX4])),C$([CH]([Br,I])([CX4])([CX4])),C$([CH2]([Br,I])([CX4])),C$([CH3]([Br,I])),C$([C]([Br,I])(=C)([CX4])),C$([CH]([Br,I])(=C)),C$(C([Br,I])(#C)),c$(c([Br,I])):2].[Br,I:3][C$(C([Br,I])([CX4])([CX4])([CX4])),C$([CH]([Br,I])([CX4])([CX4])),C$([CH2]([Br,I])([CX4])),C$([CH3]([Br,I])),C$([C]([Br,I])(=C)([CX4])),C$([CH]([Br,I])(=C)),C$(C([Br,I])(#C)),c$(c([Br,I])):4]>>[C,c:2][C,c:4]
[OH,O-]-[C$(C(=O)(O)([CX4,c])):2]=[O:3].[OH:8]-[C$([CH](O)([CX4,c])([CX4,c])),C$([CH2](O)([CX4,c])),C$([CH3](O)):6]>>[C:6][O]-[C:2]=[O:3]
[C$([CH](=C)([CX4])),C$([CH2](=C)):2]=[C$(C(=C)([CX4])([CX4])),C$([CH](=C)([CX4])),C$([CH2](=C)):3].[Br,I:7][C$([CX4]([Br,I])),c$([c]([Br,I])):4]>>[C,c:4][C:2]=[C:3]
[Cl,OH,O-:3][C$(C(=O)([CX4,c])),C$([CH](=O)):2]=[O:4].[N$([NH2,NH3+1]([CX4,c])),N$([NH]([CX4,c])([CX4,c])):6]>>[N+0:6]-[C:2]=[O:4]
[C$(C(=C)([CX4])([CX4])),C$([CH](=C)([CX4])),C$([CH2](=C)):1]=[C$(C(=C)([CX4])([CX4])),C$([CH](=C)([CX4])),C$([CH2](=C)):2].[SH:4]-[CX4:5][Br,Cl,I]>>[C:1]-[C:2]-[S:4][C:5]
[C$([C](=O)([CX4])),C$([CH](=O)):2](=[O:1])[OH,Cl,O-:6].[SH:4]-[CX4:5][Br,Cl,I]>>[CH2:2]-[S:4][C:5]
[I:1][C$(C(I)([CX4,c])([CX4,c])([CX4,c])),C$([CH](I)([CX4,c])([CX4,c])),C$([CH2](I)([CX4,c])),C$([CH3](I)):2].[C$(C(=O)([Cl,OH,O-])([CX4,c])),C$([CH]([Cl,OH,O-])(=O)):3](=[O:6])[Cl,OH,O-:5]>>[C:2]-[C:3]=[O:6]
[Cl:5][S$(S(=O)(=O)(Cl)([CX4])):2](=[O:3])=[O:4].[NH2+0,NH3+:6]-[C$(C(N)([CX4,c])([CX4,c])([CX4,c])),C$([CH](N)([CX4,c])([CX4,c])),C$([CH2](N)([CX4,c])),C$([CH3](N)),c$(c(N)):7]>>[C,c:7]-[NH+0:6][S:2](=[O:4])=[O:3]
[*:1][C:2]#[CH:3].[Br,I:4][C$(C([CX4,c])([CX4,c])([CX4,c])),C$([CH]([CX4,c])([CX4,c])),C$([CH2]([CX4,c])),C$([CH3]),c$(c):5]>>[C,c:5][C:3]#[C:2][*:1]
[C$(C(C)([CX4])([CX4])([CX4])),C$([CH](C)([CX4])([CX4])),C$([CH2](C)([CX4])),C$([CH3](C)):1][C:2]#[CH:3].[Br,I:4][C$(C(=O)([Br,I])([CX4])),C$([CH](=O)([Br,I])):5]=[O:6]>>[C:1][C:2]#[C:3][C:5]=[O:6]
[OH,O-:4]-[C$(C(=O)([OH,O-])([CX4])),C$([CH](=O)([OH,O-])):2]=[O:3]>>[Cl:5][C:2]=[O:3]
[OH:2]-[$([CX4]),c:1]>>[Br:3][C,c:1]
[OH:2]-[$([CX4]),c:1]>>[Cl:3][C,c:1]
[OH,O-:3][S$(S([CX4])):2](=[O:4])=[O:5]>>[Cl:6][S:2](=[O:5])=[O:4]
[OH+0,O-:5]-[C:3](=[O:4])-[C$([CH]([CX4])),C$([CH2]):2]>>[OH+0,O-:5]-[C:3](=[O:4])-[C:2]([Br:6])
[OH+0,O-:5]-[C:3](=[O:4])-[C$([CH]([CX4])),C$([CH2]):2]>>[OH+0,O-:5]-[C:3](=[O:4])-[C:2]([Cl:6])
[Cl,I,Br:7][c:1]1[c:2][c:3][c:4][c:5][c:6]1>>[N:9]#[C:8][c:1]1[c:2][c:3][c:4][c:5][c:6]1
[OH,NH2,NH3+:3]-[CH2:2]-[C$(C([CX4,c])([CX4,c])([CX4,c])),C$([CH]([CX4,c])([CX4,c])),C$([CH2]([CX4,c])),C$([CH3]),c$(c):1]>>[C,c:1][C:2]#[N:4]