From ee4c829fbf3de74aa64c7d5d47bf1fd974cfba1b Mon Sep 17 00:00:00 2001 From: Max Franz Date: Mon, 9 Dec 2024 10:34:36 -0500 Subject: [PATCH] Add FCOSE gnee-gene demo to replace Cola gene-gene demo - While Cola is a good layout, FCOSE is faster and provides better compound support. It's our default recommendation in the blog (https://blog.js.cytoscape.org/2020/05/11/layouts/). - The Cola demo used to be the first one at the top of the demos. It gives the impression that it's our top/default pick. - People end up complaining, "Why can't I do X with Cola?" If they were to use FCOSE first, they'd get a better result most of the time. --- documentation/demos/fcose-gene/code.js | 239 + documentation/demos/fcose-gene/cy-style.json | 144 + documentation/demos/fcose-gene/data.json | 12895 +++++++++++++++++ documentation/demos/fcose-gene/index.html | 53 + documentation/demos/fcose-gene/style.css | 101 + documentation/docmaker.json | 2 +- documentation/img/demos/fcose-gene.png | Bin 0 -> 105950 bytes 7 files changed, 13433 insertions(+), 1 deletion(-) create mode 100644 documentation/demos/fcose-gene/code.js create mode 100644 documentation/demos/fcose-gene/cy-style.json create mode 100644 documentation/demos/fcose-gene/data.json create mode 100644 documentation/demos/fcose-gene/index.html create mode 100644 documentation/demos/fcose-gene/style.css create mode 100644 documentation/img/demos/fcose-gene.png diff --git a/documentation/demos/fcose-gene/code.js b/documentation/demos/fcose-gene/code.js new file mode 100644 index 0000000000..4e97fa700e --- /dev/null +++ b/documentation/demos/fcose-gene/code.js @@ -0,0 +1,239 @@ +/* global Promise, fetch, window, cytoscape, document, tippy, _ */ + +Promise.all([ + fetch('cy-style.json') + .then(function(res) { + return res.json(); + }), + fetch('data.json') + .then(function(res) { + return res.json(); + }) +]) + .then(function(dataArray) { + var h = function(tag, attrs, children){ + var el = document.createElement(tag); + + Object.keys(attrs).forEach(function(key){ + var val = attrs[key]; + + el.setAttribute(key, val); + }); + + children.forEach(function(child){ + el.appendChild(child); + }); + + return el; + }; + + var t = function(text){ + var el = document.createTextNode(text); + + return el; + }; + + var $ = document.querySelector.bind(document); + + var cy = window.cy = cytoscape({ + container: document.getElementById('cy'), + style: dataArray[0], + elements: dataArray[1], + layout: { name: 'grid' } // fixed, non-equal positions ensure deterministic fcose results + }); + + // values modified by sliders + var nodeRepulsionVal = 4500; + var idealEdgeLengthVal = 1; + + var params = { + name: 'fcose', + nodeRepulsion: n => nodeRepulsionVal, + idealEdgeLength: e => idealEdgeLengthVal / e.data('weight'), + animate: true, + randomize: false + }; + var layout = makeLayout({ animate: false }); + + layout.run(); + + var $btnParam = h('div', { + 'class': 'param' + }, []); + + var $config = $('#config'); + + $config.appendChild( $btnParam ); + + var sliders = [ + { + label: 'Edge length', + update: sliderVal => idealEdgeLengthVal = sliderVal, + initVal: idealEdgeLengthVal, + min: 1, + max: 5, + step: 0.1 + }, + + { + label: 'Node repulsion', + update: sliderVal => nodeRepulsionVal = sliderVal, + initVal: nodeRepulsionVal, + min: 4500, + max: 1000000, + step: 1 + } + ]; + + var buttons = [ + { + label: h('span', { 'class': 'fa fa-random' }, []), + layoutOpts: { + randomize: true, + animate: true + } + }, + + { + label: h('span', { 'class': 'fa fa-play' }, []), + layoutOpts: { + randomize: false, + animate: true + } + } + ]; + + sliders.forEach( makeSlider ); + + buttons.forEach( makeButton ); + + function makeLayout( opts ){ + params.randomize = (opts || {}).randomize || false; + + for( var i in opts ){ + params[i] = opts[i]; + } + + return cy.layout( Object.assign({}, params) ); + } + + function makeSlider( opts ){ + var $input = h('input', { + id: 'slider-'+opts.param, + type: 'range', + min: opts.min, + max: opts.max, + step: opts.step, + value: opts.initVal, + 'class': 'slider' + }, []); + + var $param = h('div', { 'class': 'param' }, []); + + var $label = h('label', { 'class': 'label label-default', for: 'slider-'+opts.param }, [ t(opts.label) ]); + + $param.appendChild( $label ); + $param.appendChild( $input ); + + $config.appendChild( $param ); + + var update = _.throttle(function(){ + opts.update(parseFloat($input.value)); + + layout.stop(); + layout = makeLayout({ animate: true }); + layout.run(); + }, 1000/4, { trailing: true }); + + $input.addEventListener('input', update); + $input.addEventListener('change', update); + } + + function makeButton( opts ){ + var $button = h('button', { 'class': 'btn btn-default' }, [ opts.label ]); + + $btnParam.appendChild( $button ); + + $button.addEventListener('click', function(){ + layout.stop(); + + layout = makeLayout( opts.layoutOpts ); + layout.run(); + }); + } + + var makeTippy = function(node, html){ + return tippy( node.popperRef(), { + html: html, + trigger: 'manual', + arrow: true, + placement: 'bottom', + hideOnClick: false, + interactive: true + } ).tooltips[0]; + }; + + var hideTippy = function(node){ + var tippy = node.data('tippy'); + + if(tippy != null){ + tippy.hide(); + } + }; + + var hideAllTippies = function(){ + cy.nodes().forEach(hideTippy); + }; + + cy.on('tap', function(e){ + if(e.target === cy){ + hideAllTippies(); + } + }); + + cy.on('tap', 'edge', function(e){ + hideAllTippies(); + }); + + cy.on('zoom pan', function(e){ + hideAllTippies(); + }); + + cy.nodes().forEach(function(n){ + var g = n.data('name'); + + var $links = [ + { + name: 'GeneCard', + url: 'http://www.genecards.org/cgi-bin/carddisp.pl?gene=' + g + }, + { + name: 'UniProt search', + url: 'http://www.uniprot.org/uniprot/?query='+ g +'&fil=organism%3A%22Homo+sapiens+%28Human%29+%5B9606%5D%22&sort=score' + }, + { + name: 'GeneMANIA', + url: 'http://genemania.org/search/human/' + g + } + ].map(function( link ){ + return h('a', { target: '_blank', href: link.url, 'class': 'tip-link' }, [ t(link.name) ]); + }); + + var tippy = makeTippy(n, h('div', {}, $links)); + + n.data('tippy', tippy); + + n.on('click', function(e){ + tippy.show(); + + cy.nodes().not(n).forEach(hideTippy); + }); + }); + + $('#config-toggle').addEventListener('click', function(){ + $('body').classList.toggle('config-closed'); + + cy.resize(); + }); + + }); diff --git a/documentation/demos/fcose-gene/cy-style.json b/documentation/demos/fcose-gene/cy-style.json new file mode 100644 index 0000000000..c84be23f36 --- /dev/null +++ b/documentation/demos/fcose-gene/cy-style.json @@ -0,0 +1,144 @@ +[{ + "selector": "core", + "style": { + "selection-box-color": "#AAD8FF", + "selection-box-border-color": "#8BB0D0", + "selection-box-opacity": "0.5" + } +}, { + "selector": "node", + "style": { + "width": "mapData(score, 0, 0.006769776522008331, 20, 60)", + "height": "mapData(score, 0, 0.006769776522008331, 20, 60)", + "content": "data(name)", + "font-size": "12px", + "text-valign": "center", + "text-halign": "center", + "background-color": "#555", + "text-outline-color": "#555", + "text-outline-width": "2px", + "color": "#fff", + "overlay-padding": "6px", + "z-index": "10" + } +}, { + "selector": "node[?attr]", + "style": { + "shape": "rectangle", + "background-color": "#aaa", + "text-outline-color": "#aaa", + "width": "16px", + "height": "16px", + "font-size": "6px", + "z-index": "1" + } +}, { + "selector": "node[?query]", + "style": { + "background-clip": "none", + "background-fit": "contain" + } +}, { + "selector": "node:selected", + "style": { + "border-width": "6px", + "border-color": "#AAD8FF", + "border-opacity": "0.5", + "background-color": "#77828C", + "text-outline-color": "#77828C" + } +}, { + "selector": "edge", + "style": { + "curve-style": "haystack", + "haystack-radius": "0.5", + "opacity": "0.4", + "line-color": "#bbb", + "width": "mapData(weight, 0, 1, 1, 8)", + "overlay-padding": "3px" + } +}, { + "selector": "node.unhighlighted", + "style": { + "opacity": "0.2" + } +}, { + "selector": "edge.unhighlighted", + "style": { + "opacity": "0.05" + } +}, { + "selector": ".highlighted", + "style": { + "z-index": "999999" + } +}, { + "selector": "node.highlighted", + "style": { + "border-width": "6px", + "border-color": "#AAD8FF", + "border-opacity": "0.5", + "background-color": "#394855", + "text-outline-color": "#394855" + } +}, { + "selector": "edge.filtered", + "style": { + "opacity": "0" + } +}, { + "selector": "edge[group=\"coexp\"]", + "style": { + "line-color": "#d0b7d5" + } +}, { + "selector": "edge[group=\"coloc\"]", + "style": { + "line-color": "#a0b3dc" + } +}, { + "selector": "edge[group=\"gi\"]", + "style": { + "line-color": "#90e190" + } +}, { + "selector": "edge[group=\"path\"]", + "style": { + "line-color": "#9bd8de" + } +}, { + "selector": "edge[group=\"pi\"]", + "style": { + "line-color": "#eaa2a2" + } +}, { + "selector": "edge[group=\"predict\"]", + "style": { + "line-color": "#f6c384" + } +}, { + "selector": "edge[group=\"spd\"]", + "style": { + "line-color": "#dad4a2" + } +}, { + "selector": "edge[group=\"spd_attr\"]", + "style": { + "line-color": "#D0D0D0" + } +}, { + "selector": "edge[group=\"reg\"]", + "style": { + "line-color": "#D0D0D0" + } +}, { + "selector": "edge[group=\"reg_attr\"]", + "style": { + "line-color": "#D0D0D0" + } +}, { + "selector": "edge[group=\"user\"]", + "style": { + "line-color": "#f0ec86" + } +}] diff --git 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+ "weight": 0.019493334, + "group": "spd", + "networkId": 1230, + "networkGroupId": 24, + "intn": true, + "rIntnId": 594, + "id": "e592" + }, + "position": {}, + "group": "edges", + "removed": false, + "selected": false, + "selectable": true, + "locked": false, + "grabbed": false, + "grabbable": true, + "classes": "" +}] diff --git a/documentation/demos/fcose-gene/index.html b/documentation/demos/fcose-gene/index.html new file mode 100644 index 0000000000..52ee64cf28 --- /dev/null +++ b/documentation/demos/fcose-gene/index.html @@ -0,0 +1,53 @@ + + + + + + + + FCOSE/Cytoscape.js + + + + + + + + + + + + + + + + + + + + + + + + + +
+ + + +
+ +
+ FCOSE/Cytoscape.js demo + +

This is a demo of a graph of gene-gene interactions that uses FCOSE for layout and Cytoscape.js for its graph model and visualisation. Use the controls below to alter the FCOSE layout parameters.

+

+ Data by GeneMANIA
+ Visualisation by Cytoscape.js
+ Layout by FCOSE +

+
+ +
+ + diff --git a/documentation/demos/fcose-gene/style.css b/documentation/demos/fcose-gene/style.css new file mode 100644 index 0000000000..888bd3ef60 --- /dev/null +++ b/documentation/demos/fcose-gene/style.css @@ -0,0 +1,101 @@ + +html { + width: 100%; + height: 100%; +} + +body { + font: 14px helvetica neue, helvetica, arial, sans-serif; + width: 100%; + height: 100%; + overflow: hidden; +} + +#cy { + position: absolute; + left: 0; + top: 0; + bottom: 0; + right: 17em; +} + +.config { + position: absolute; + right: 0; + top: 0; + bottom: 0; + width: 17em; + background: rgba(0, 0, 0, 0.666); + box-sizing: border-box; + padding: 1em; + color: #fff; + transition-property: opacity; + transition-duration: 250ms; + transition-timing-function: ease-out; + overflow: auto; + z-index: 1; +} + +.param { + margin-bottom: 1em; +} + +.preamble { + margin-bottom: 2em; +} + +p { + margin: 0.5em 0; + font-size: 0.8em; +} + +.param button { + width: 3em; + margin-right: 0.25em; + text-align: center; +} + +a, +a:hover { + color: #8BB0D0; +} + +.label { + display: block; +} + +.slider { + display: block; + width: 100%; + margin: 0; +} + +.config-toggle { + position: absolute; + right: 0; + top: 0; + padding: 1em; + margin: 0.2em; + cursor: pointer; + color: #fff; + z-index: 9999999; +} + +.config-closed .config { + opacity: 0; + pointer-events: none; +} + +.config-closed #cy { + right: 0; +} + +.tip-link { + display: block; +} + +@media (max-width: 600px){ + #cy { + right: 0; + } +} diff --git a/documentation/docmaker.json b/documentation/docmaker.json index 0c1b81a79f..ba2c1f4754 100644 --- a/documentation/docmaker.json +++ b/documentation/docmaker.json @@ -33,7 +33,7 @@ "name": "Demos", "md": "demos", "demos": [ - { "name": "Cola.js gene-gene graph", "id": "colajs-graph" }, + { "name": "FCOSE gene-gene graph", "id": "fcose-gene" }, { "name": "Tokyo railways", "id": "tokyo-railways" }, { "name": "Wine & cheese", "id": "wine-cheese-map", "github": "cytoscape/wineandcheesemap", 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