diff --git a/dandiapi/api/models/asset.py b/dandiapi/api/models/asset.py
index 1b6e0b743..99b030299 100644
--- a/dandiapi/api/models/asset.py
+++ b/dandiapi/api/models/asset.py
@@ -240,6 +240,7 @@ def is_different_from(
         asset_blob: AssetBlob | EmbargoedAssetBlob | None = None,
         zarr_archive: ZarrArchive | EmbargoedZarrArchive | None = None,
         metadata: dict,
+        path: str,
     ) -> bool:
         from dandiapi.zarr.models import EmbargoedZarrArchive, ZarrArchive
 
@@ -263,6 +264,9 @@ def is_different_from(
         if isinstance(zarr_archive, EmbargoedZarrArchive):
             raise NotImplementedError
 
+        if self.path != path:
+            return True
+
         if self.metadata != metadata:
             return True
 
diff --git a/dandiapi/api/services/asset/__init__.py b/dandiapi/api/services/asset/__init__.py
index 219579e00..a87fd4fc5 100644
--- a/dandiapi/api/services/asset/__init__.py
+++ b/dandiapi/api/services/asset/__init__.py
@@ -66,7 +66,10 @@ def change_asset(
     new_metadata_stripped = Asset.strip_metadata(new_metadata)
 
     if not asset.is_different_from(
-        asset_blob=new_asset_blob, zarr_archive=new_zarr_archive, metadata=new_metadata_stripped
+        asset_blob=new_asset_blob,
+        zarr_archive=new_zarr_archive,
+        metadata=new_metadata_stripped,
+        path=path,
     ):
         return asset, False
 
diff --git a/dandiapi/api/tests/test_asset.py b/dandiapi/api/tests/test_asset.py
index c0f250cd8..d048e7329 100644
--- a/dandiapi/api/tests/test_asset.py
+++ b/dandiapi/api/tests/test_asset.py
@@ -895,6 +895,32 @@ def test_asset_create_existing_path(api_client, user, draft_version, asset_blob,
     assert resp.status_code == 409
 
 
+@pytest.mark.django_db
+def test_asset_rest_rename(api_client, user, draft_version, asset_blob):
+    assign_perm('owner', user, draft_version.dandiset)
+    api_client.force_authenticate(user=user)
+
+    # Create asset
+    metadata = {'path': 'foo/bar', 'schemaVersion': settings.DANDI_SCHEMA_VERSION}
+    asset = add_asset_to_version(
+        user=user, version=draft_version, asset_blob=asset_blob, metadata=metadata
+    )
+
+    # Change path and make update request
+    metadata['path'] = 'foo/bar2'
+    resp = api_client.put(
+        f'/api/dandisets/{draft_version.dandiset.identifier}/versions/{draft_version.version}/'
+        f'assets/{asset.asset_id}/',
+        {'metadata': metadata, 'blob_id': asset.blob.blob_id},
+        format='json',
+    )
+
+    # Ensure new asset with new path was created
+    assert resp.status_code == 200
+    assert resp.json()['path'] == metadata['path']
+    assert resp.json()['asset_id'] != str(asset.asset_id)
+
+
 @pytest.mark.django_db
 def test_asset_rest_update(api_client, user, draft_version, asset, asset_blob):
     assign_perm('owner', user, draft_version.dandiset)