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Duplicates in CircRNACount multiple read counts #108

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valentinamarchi1 opened this issue Aug 14, 2024 · 0 comments
Open

Duplicates in CircRNACount multiple read counts #108

valentinamarchi1 opened this issue Aug 14, 2024 · 0 comments

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@valentinamarchi1
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Hi!
I was running 0.5.0 DCC on single-end data and I found in more than one sample the same circRNAs candidate (so same chromosome, star and end, in CircRNACount output) with different read counts (as you can see in the attached picture).

Screenshot 2024-08-14 at 11 59 02

All other outputs files were successfully generated (CircCoordinates, LinearCount, CircSkipJunctions) and i also attach the .log file for the sample reported as example in the CircRNACount output. DCC-2024-07-14_1406.log

Could you give some advice to overcome this issue? Should i select one count in respect to the other, should i do the mean of counts for each non-unique cirnRNAs candidate? How is it possibile to detect the same candidate but with different read counts?

Thank you in advance!

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