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template.html
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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8">
<meta http-equiv="X-UA-Compatible" content="IE=edge">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>Longevity report</title>
<style >
/*general styles*/
*{
box-sizing: border-box;
scroll-behavior: smooth;
}
ol{
margin-top: 2vw;
margin-bottom: 2vw;
font-size: 1.1vw;
}
ol li{
margin: 1vw 0;
}
a {
color: #87cec3;
text-decoration: none;
}
a:hover{
color: #92e0d3;
}
body{
background-image: linear-gradient(to left bottom, rgb(249, 246, 240), #f8f6ec, #f6f6e8, #f2f7e6, #edf8e4, #e5f9e8, #dff9ec, #d9f9f2, #d8f7fb, #def5ff, #e7f1ff, #f0eefd) !important;
background-repeat: no-repeat;
background-attachment: fixed;
color:rgb(66, 92, 88);
font-family: Arial, Helvetica, sans-serif;
}
canvas{
width: 18vw;
height: 9vw;
}
/*style for intro section*/
.intro{
width: 60%;
text-align: center;
margin-left: auto;
margin-right: auto;
line-height: 3;
font-size: 1vw;
}
.intro p{
color:rgb(84, 85, 110);
line-height: 2em;
font-size: 1.3em;
font-weight: 400;
}
.intro a{
word-wrap: break-word;
}
.intro ul{
padding-left: 0;
margin-left: auto;
margin-right: auto;
font-weight: 500;
margin-top: 40px;
list-style-type: none;
margin-bottom: 120px;
}
.li1{
font-weight: 400;
font-size: 1.3vw;
}
#prs, #prs1{
color: #b2e457;
}
.attention strong{
color: rgb(71, 155, 148);
font-size: 1.25vw;
}
.attention p{
color:#3a6e65;
}
.attention{
margin-top: 4vw;
margin-bottom: 4vw;
margin-left: auto;
margin-right: auto;
width: 65%;
padding: 0.8vw 1.7vw 0.8vw 1.7vw;
font-size: 0.8vw;
border:rgb(122, 189, 183)solid 5px;
border-radius: 30px;
background-color: white;
box-shadow: 0px 5px 5px 0px #4a887c;
}
.first{
margin-top: 3vw;
color:#269292;
font-size: 3vw;
}
/*table styles*/
table.ui{
transition: max-height 0.5s ease-in;
border-radius: 0.28571429rem;
font-size: 0.8vw;
background: white;
width: 85%;
margin-right:auto;
margin-left: auto;
border-radius: 0.28571429rem;
padding: 0.78571429em 0.78571429em;
text-align: left;
border-collapse: collapse;
vertical-align: middle;
border: 1px solid rgba(34,36,38,.15);
line-height: 1.4285em;
}
table.ui th{
background: #f9fafb;
color: rgba(0,0,0,.87);
padding: 0.92857143em 0.78571429em;
vertical-align: inherit;
font-style: none;
font-weight: 700;
text-transform: none;
border-bottom: 1px solid rgba(34,36,38,.1);
border-right: 1px solid rgba(34,36,38,.1);
}
table.ui.selectable.celled.teal.table tr:hover{
background-color: #eef1f5;
}
table.ui td{
border-bottom: 1px solid rgba(34,36,38,.1);
border-top: none;
border-left: 1px solid rgba(34,36,38,.1);
padding: 10px 10px 10px 10px;
}
table.ui td:first-child{
border-left: none;
}
.ui.celled.teal.table.prs
{
width: 100%;
margin-top: 3vw;
color:rgb(66, 92, 88);
box-shadow: 0 1px 3px 1px rgba(118, 49, 40, 0.3);
border-top: 0.4em solid #56C3BD;
}
.ui.selectable.celled.teal.table.table.variants{
margin-top: 0px;
box-shadow: 0 1px 3px 1px rgba(118, 49, 40, 0.3);
margin-bottom: 80px;
border-top: 0.4em solid rgb(101, 189, 162);
}
.ui.celled.teal.table.table.drugs{
box-shadow: 0 1px 3px 1px rgba(118, 49, 40, 0.3);
border-top: 0.4em solid rgb(101, 189, 162);
margin-top:0;
}
.ui.selectable.celled.teal.table.table.cancer{
box-shadow: 0 1px 3px 1px rgba(118, 49, 40, 0.3);
margin-bottom: 80px ;
border-top: 0.4em solid rgb(101, 189, 162);
}
/*button style*/
div.ui.tiny.circular.compact.positive.button {
border-radius: 10em;
background-color: #86caf7;
color: #fff;
padding: 0.58928571em 1.125em 0.58928571em;
cursor: pointer;
display: inline-block;
min-height: 1em;
outline: 0;
border: none;
vertical-align: baseline;
margin: 0 0.25em 0 0;
font-weight: 700;
line-height: 1em;
font-style: normal;
text-align: center;
}
div.ui.tiny.circular.compact.negative.button {
border-radius: 10em;
background-color: #a6f069;
color: #fff;
padding: 0.58928571em 1.125em 0.58928571em;
cursor: pointer;
display: inline-block;
min-height: 1em;
outline: 0;
border: none;
vertical-align: baseline;
margin: 0 0.25em 0 0;
font-weight: 700;
line-height: 1em;
font-style: normal;
text-align: center;
}
th, td {
padding: 2px;
}
.accordion.accordion0.accordion1.prs-panel{
margin-top: 0.7vw;
}
/* accordions styles*/
.accordion0{
position: relative;
border:rgb(101, 189, 162) solid 6px;
border-bottom: none;
width: 50%;
margin-left: 25%;
margin-right: 25%;
text-align: left;
padding-left: 2vw;
height: 4vw;
font-size: 1.5vw;
background-color: rgba(255, 255, 255, 0.5);
border-radius: 10px 10px 10px 10px;
margin-top: 0.01vw;
color: rgb(81, 139, 122);
margin-top: 0.7vw;
border-bottom: none;
cursor: pointer;
}
.accordion.accordion-heading.active, .accordion:hover{
background-color: rgba(255, 255, 255, 0.2);
}
.accordion.accordion-heading:hover, .accordion.accordion-heading.active:hover{
color:rgb(127, 201, 182);
}
.accordion1{
margin-top: 3vw;
}
.accordion2{
border:#577de4 solid 5px;
}
/* accordion heading styles*/
.accordion-heading{
width: 50%;
margin-left: 25%;
margin-right: 25%;
user-select: none;
height: 5vw;
padding-top: 1vw;
padding-bottom: 1vw;
cursor: pointer;
border:rgb(101, 189, 162, 0.5) solid 6px;
background-color: rgba(255, 255, 255, 0.5);
font-size: 1.7vw;
border-radius: 15px;
margin-top: 2vw;
transition-property: width, margin-left, margin-right;
transition-duration: 0.2s, 0.2s, 0.2s;
color:rgb(47, 116, 106);
border-bottom: none;}
.accordion-heading:hover{
background-color: rgba(255, 255, 255, 0.5);
}
/*used in each div after description and recommendation buttons*/
/*exist in both descr and rec*/
.board{
width: 50%;
margin-top: 40px;
padding-top: 10px;
color:rgb(84, 85, 110);
margin-right:auto;
margin-left:auto;
font-size: 1.1vw;
}
.board p{
line-height: 1.7;
font-weight: 400;
}
.board .how_to{
font-size: 1.3vw;
color:#29332f
}
.panel{
padding: 1.5vw 2.5vw 1.5vw 2.5vw;
display: none;
border:rgb(66, 92, 88) solid 3px;
border-bottom-left-radius: 15px;
border-bottom-right-radius: 15px;
border-top: none;
background-color: white;
margin-top: 0px;
}
/*just styles to colour panels for results and descriptions*/
.variants.panel{
border: rgb(101, 189, 162) 6px solid;
border-top:none;
}
.panel-results{
border: #a0cf47 6px solid;
border-top:none;
}
/* only appears after results*/
.content{
margin-left: auto;
margin-right: auto;
overflow-x: auto;
transition: max-height 0.5s ease-in;
display: none;
}
.hidden{
max-height: 0;
overflow: hidden;
max-height: 0;
transition: max-height 0.5s ease-in;
}
/*styles for accordion to work*/
.basic-panel, .panel, .content{
max-height: 0;
overflow: hidden;
transition-property: max-height, width;
transition-duration: 0.2s, 0.5s;
}
.basic-panel{
background-color: rgba(255, 255, 255, 0.2);
margin-left: auto;
margin-right: auto;
width: 85%;
border-right: rgb(101, 189, 162, 0.5) solid 6px;
border-left: rgb(101, 189, 162, 0.5) solid 6px;
border-bottom-left-radius: 3%;
border-bottom-right-radius: 3%;
}
/*animation styles*/
.accordion-result, .accordion-result.active{
transition-property: width, margin-left, margin-right;
transition-duration: 0.2s, 0.2s, 0.2s;
}
/*styles for buttons inside basic-panel*/
.basic-panel {
width: 85%;
}
.accordion1, .basic-panel .accordion1 +.panel-description{
width: 50%;
margin-left: 25%;
margin-right: 25%;
}
/* styles to color names of modules*/
#variants{
color: rgb(57, 145, 123);
}
/*colors for drugs module*/
.accordion.accordion0.accordion1.accord_drugs, .accordion.accordion0.accordion-result.accord_drugs{
color: rgb(81, 139, 122);
}
.accord_drugs{
border: rgb(101, 189, 162) 6px solid;
border-bottom: none;
}
/* styles for arrow */
.accordion0 div{
border-top: rgba(61, 128, 119, 0.7) solid 0.3vw;
border-right:rgba(61, 128, 119, 0.7) solid 0.3vw;
border-radius: 5px;
height: 1vw;
width:1vw;
margin-right: 1vw;
display: inline-block;
transform: rotate(45deg);
transition: transform 0.5s;
}
.accordion0.active div{
transform: rotate(135deg);
}
/* styles for drug module*/
.accordion1.accord_drugs, .panel-description.accord_drugs{
border: rgb(101, 189, 162) 6px solid;
}
.accordion1.accord_drugs{
border-bottom: none;
}
.panel-description.accord_drugs{
border-top: none;
}
.accordion.accordion0.accordion1.prs-panel.major-risk.special{
margin-top: 3vw;
font-size: 1.7vw;
}
/*styles for major risks module*/
.variants.panel.major-risk{
border: rgb(101, 189, 162) 6px solid;
border-bottom: none;}
.variants.panel.major-risk{
border-top:none;
}
.accordion0.major-risk{
color:rgb(81, 139, 122);
}
.content-variants.major-risk{
border:none;
}
.basic-panel.major-risk{
border-bottom: none;
border-top: none;
}
.last.inside, .last{
height:4vw;
}
.last.outside{
height: 6vw;
}
h2{
margin-top: 4vw;
margin-bottom: 20px;
}
h2, h1{
text-align: center;
font-size: 2.5vw;
font-weight: 500;
}
/* below is style for navigation button */
#toTop{
z-index: 100;
height: 70px;
width: 70px;
background-color: #308499;
border-radius: 50%;
position: fixed;
right: 2.35%;
bottom: 10%;
display:none;
box-shadow: 3px 3px 15px rgb(30, 77, 88, 0.7);
}
#toTop:hover{
background-color:#56C3BD;
}
.arrow{
position: absolute;
bottom: 10%;
z-index: 10;
}
.bodypart{
width: 0;
height: 0;
border-left: 16px solid transparent;
border-right: 16px solid transparent;
border-bottom: 16px solid white;
right: 20px;
top:20%;
}
.line{
right: 31px;
bottom: 18px;
background: white;
width: 8px;
height: 33px;
}
@media only screen and (max-width: 1400px) {
.accordion.accordion0.accordion1.prs-panel.major-risk.special {
font-size: 2.5vw;
}
.intro{
width: 75%;
font-size: 1.4vw;
}
.first{
font-size: 4.5vw;
}
.attention p{
font-size: 1.6vw;
}
.attention{
margin-top: 7vw;
margin-bottom:7vw;
width: 90%;
}
.attention strong{
font-size: 1.8vw;
}
.first{
margin-top: 8vw;
}
h2{
line-height: 5vw;
font-size: 4vw;
}
.li1{
font-size: 2.2vw;
}
.accordion0, .accordion-heading, .accordion0.accordion.accordion1{
width:80%;
margin-left:10%;
margin-right:10%;
height: 8vw;
font-size: 2.5vw;
}
.panel,.accordion0.accordion.accordion1 +.panel-description{
width:80%;
margin-left: 10%;
margin-right: 10%;
font-size: 1.7vw;
padding: 2.5vw 3.5vw 2.5vw 3.5vw;
}
.accordion0 div{
height: 2vw;
width:2vw;
border-top: rgba(61, 128, 119, 0.7) solid 0.6vw;
border-right: rgba(61, 128, 119, 0.7) solid 0.6vw;
margin-right: 2vw;
}
.basic-panel{
width: 98%;
}
ol{
margin-top:6vw;
margin-bottom: 6vw;
font-size: 1.7vw;
}
ol li{
margin-top: 2vw;
}
table.ui{
font-size: 1.3vw;
}
table.prs{
width: 100%;
font-size: 1.2vw;
}
.board .how_to{
font-size: 2.2vw;
}
canvas{
width: 36vw;
height: 18vw;
}
#variants > button .module-button{
width: 70%;
margin-left: 15%;
margin-right: 15%;
}
/*styles for button to top*/
#toTop{
right: 4%;
}
.acordiv{
width:85%
}
.ui.celled.teal.table.table.drugs td, .ui.selectable.celled.teal.table.table.cancer td{
padding: 5px;
}
.ui.selectable.celled.teal.table.table.cancer.cancer1 td, .ui.selectable.celled.teal.table.table.cancer.cardio th{
padding: 5px;
}
.ui.celled.teal.table.table.drugs, .ui.selectable.celled.teal.table.table.cancer,.ui.selectable.celled.teal.table.table.variants{
width: 98%;
}
/*.ui.selectable.celled.teal.table.table.cancer.cardio{
width: 90%;
}*/
.ui.selectable.celled.teal.table.table.cancer.cardio td, .ui.celled.teal.table.table.drugs td{
padding: 2px;
font-size: 1.1vw;
}
h2{
margin-top:18vw;
}
}
@media only screen and (max-width: 600px){
.accordion.accordion0.accordion1.prs-panel.major-risk.special {
font-size: 4vw;
}
.intro{
width: 90%;
font-size: 3.1vw;
}
.attention p{
font-size: 3.1vw;
}
.attention strong{
font-size: 4vw;
}
.attention{
padding: 3vw 4vw 3vw 4vw;
}
.basic-panel, .basic-panel.major-risk{
width:100%;
}
.accordion0, .accordion-heading, .accordion0.accordion.accordion1{
height: 12vw;
font-size: 4vw;
width: 95%;
margin-left: 2.5%;
margin-right: 2.5%;
}
.panel, .accordion0.accordion.accordion1 +.panel-description, .accordion0.accordion.accordion1 + .prs-panel {
margin-left:2.5%;
margin-right:2.5%;
width:95%;
font-size: 3vw;;
margin-bottom: 1vw;
margin-top: 0;
}
.accordion0 div{
height: 3.5vw;
width:3.5vw;
border-top: rgba(61, 128, 119, 0.7) solid 1vw;
border-right: rgba(61, 128, 119, 0.7) solid 1vw;
margin-right: 2vw;
margin-left: 1vw;
}
.accordion.accordion-heading{
height: 16vw;
}
.first{
font-size: 8vw;
}
.li1{
font-size: 4.8vw;
}
.attention{
margin-top: 10vw;
margin-bottom: 10vw;
width: 90%;
border: rgb(71, 194, 184) solid 2px;
border-radius: 13px;
}
.first{
margin-top: 15vw;
}
table .ui{
margin-bottom: 1vw;
}
h2{
line-height: 8vw;
font-size: 7vw;
}
h1{
line-height: 9vw;
font-size: 6vw;
}
h2{
margin-top: 20vw;
}
ol li{
margin-top: 4vw;
}
ol{
margin-top: 10vw;
margin-bottom: 10vw;
}
.intro ul{
margin-bottom:15vw;
}
.board.prs,.board.drugs,.board.cancer, .board.variants, .board.variants ol{
font-size: 2.7vw;
width: 95%;
}
.board.variants{
margin-bottom: 15vw;
}
.board .how_to{
font-size: 3.7vw;
}
.ui.celled.teal.table.prs{
font-size: 2.1vw;
}
.ui.celled.teal.table.table.drugs td, .ui.selectable.celled.teal.table.table.cancer td, .ui.celled.teal.table.table.drugs th, .ui.selectable.celled.teal.table.table.cancer th{
padding: 2px;
font-size: 1.3vw;
line-height: 2.5vw;
}
.ui.selectable.celled.teal.table.table.variants td, .ui.selectable.celled.teal.table.table.variants th{
font-size: 1.5vw;
padding: 3px;
line-height: 2.3vw;
}
.ui.selectable.celled.teal.table.table.variants{
margin-bottom: 1vw;
}
.ui.padded.table{
font-size: 1.5vw;
line-height: 2.3vw;.ui.selectable.celled.teal.table.table.cancer.card
}
.ui.selectable.celled.teal.table.table.cancer.cancer1 td{
padding: 2px;
font-size: 1.4vw;
}
.ui.celled.teal.table.table.drugs, .ui.selectable.celled.teal.table.table.cancer{
width: 100%;
}
.ui.celled.teal.table.table.drugs{
font-size: 1.4;
}
.ui.selectable.celled.teal.table.table.cancer.bigger th, .ui.selectable.celled.teal.table.table.cancer.bigger td{
font-size: 1.5vw;
line-height: 2.6vw;
}
.ui.selectable.celled.teal.table.table.cancer.cardio td{
font-size: 1.3vw;
}
.acordiv{
width:100%;
}
canvas{
width: 34vw;
height: 17vw;
}
}
</style>
<script>
function expand(obj){
var tdEl = obj.children[0];
var el = obj.nextSibling;
if (el.nodeName == "#text")
el = el.nextSibling;
var parent = el.parentElement;
parent = parent.parentElement.parentElement;
board = parent.parentElement;
el.style.display = "";
el.style.maxHeight = el.scrollHeight + "px";
if (board.classList.contains("basic-panel")){
board.style.maxHeight= Number(board.style.maxHeight.slice(0, -2)) + el.scrollHeight + "px";
}
parent.style.maxHeight= Number(parent.style.maxHeight.slice(0, -2)) + el.scrollHeight + "px";
tdEl.innerHTML = "<div class=\"ui tiny circular compact negative button\">-</div>";
//obj.style.backgroundColor = "#e0e0e0";
}
function collapse(obj){
var tdEl = obj.children[0];
var el = obj.nextSibling;
if (el.nodeName == "#text")
el = el.nextSibling;
var parent = el.parentElement;
parent = parent.parentElement.parentElement;
board = parent.parentElement;
if (board.classList.contains("basic-panel")){
board.style.maxHeight= Number(board.style.maxHeight.slice(0, -2)) - el.scrollHeight + "px";
}
parent.style.maxHeight= Number(parent.style.maxHeight.slice(0, -2)) - el.scrollHeigh + "px";
el.style.maxHeight = '0';
setTimeout(function() {
el.style.display = "none";
}, 150);
tdEl.innerHTML = "<div class=\"ui tiny circular compact positive button\">+</div>";
//obj.style.backgroundColor = "#eeeeee";
}
function doOnClick(obj){
var tdEl = obj.children[0];
var el = obj.nextSibling;
if (el.nodeName == "#text")
el = el.nextSibling;
if(el.style.display == "none")
expand(obj);
/*el.parentElement.maxHeight += el.clientHeight;*/
else
collapse(obj);
}
function collapseExpandAll(obj, id){
var el = document.getElementById(id);
if(obj.innerHTML == "<div class=\"ui tiny circular compact positive button\">+</div>"){
for(var i in el.children)
if(el.children[i].children && el.children[i].children.length > 3)
expand(el.children[i]);
obj.innerHTML = "<div class=\"ui tiny circular compact negative button\">-</div>";
} else {
for(var i in el.children)
if(el.children[i].children && el.children[i].children.length > 3)
collapse(el.children[i]);
obj.innerHTML = "<div class=\"ui tiny circular compact positive button\">+</div>";
}
}
var normalData = {'x': {'max': 2.82, 'min': -2.794, 'data': [-2.794, -2.569, -2.428, -2.323, -2.238, -2.167, -2.106, -2.052, -2.003, -1.958, -1.917, -1.879, -1.844, -1.811, -1.779, -1.75, -1.721, -1.694, -1.669, -1.644, -1.62, -1.597, -1.575, -1.554, -1.533, -1.513, -1.494, -1.475, -1.457, -1.439, -1.421, -1.404, -1.388, -1.372, -1.356, -1.34, -1.325, -1.31, -1.295, -1.281, -1.267, -1.253, -1.239, -1.226, -1.213, -1.2, -1.187, -1.174, -1.162, -1.15, -1.138, -1.126, -1.114, -1.103, -1.091, -1.08, -1.069, -1.058, -1.047, -1.036, -1.025, -1.015, -1.004, -0.994, -0.984, -0.974, -0.964, -0.954, -0.944, -0.934, -0.925, -0.915, -0.906, -0.896, -0.887, -0.878, -0.868, -0.859, -0.85, -0.841, -0.832, -0.824, -0.815, -0.806, -0.797, -0.789, -0.78, -0.772, -0.763, -0.755, -0.747, -0.739, -0.73, -0.722, -0.714, -0.706, -0.698, -0.69, -0.682, -0.674, -0.666, -0.659, -0.651, -0.643, -0.635, -0.628, -0.62, -0.613, -0.605, -0.597, -0.59, -0.583, -0.575, -0.568, -0.56, -0.553, -0.546, -0.539, -0.531, 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function drawGausian(cnvasId, p, bgColor, gausianColor, percentileColor, filledColor, invers=0){
if (invers == 1){
if (p <= 0.25){
var filledColor = '#ff9b00';
var strokeColor = '#895510';
} else if (p > 0.25 && p <= 0.45){
var filledColor = '#ffdb33';
var strokeColor = '#846925';
} else {
var filledColor = '#b4ea54';
var strokeColor = '#097050';
}
}else{
if (p <= 0.55){
var filledColor = '#b4ea54';
var strokeColor = '#097050';
} else if (p > 0.55 && p <= 0.75){
var filledColor = '#ffdb33';
var strokeColor = '#846925';
} else {
var filledColor = '#ff9b00';
var strokeColor = '#895510';
}
}
var gausianStrokeColor = '#165863';
var percColor = {0.05: '#146d40', 0.25: '#1faa5d', 0.5: '#aaaa5d', 0.75: '#b45b5d', 0.95: '#680000'};
if (invers == 1)
percColor = {0.05: '#680000', 0.25: '#b45b5d', 0.5: '#aaaa5d', 0.75: '#1faa5d', 0.95: '#146d40'};
var canvas = document.getElementById(cnvasId);
//ctx.fillStyle = "blue";
//ctx.fillRect(0, 0, , canvas.height);
var width = canvas.width;
var height = canvas.height;
var xdata = normalData['x']['data'];
var ydata = normalData['y']['data'];
var paddingH = 50;
var paddingT = 5;
var bottomShift = 2;
var xRatio = width / (normalData['x']['max'] - normalData['x']['min'])
var yRatio = (height - paddingH) / (normalData['y']['max'] - normalData['y']['min'])
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<body>
<div id="toTop">
<section class="line arrow">
</section>
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<h1 class="first" align="center">Longevity Report</h1>
<br/>
<div class="intro">
<p></p>
<p><This report provides data about your longevity genetics. Longevity and healthy lifespan are among the most complex phenotypes, with the heritability of age at death in adulthood being approximately 25 %. So, other 75 % is highly dependent on your lifestyle.
</p>
<p></p>
<p>This report is based on your raw file genome’s data cross-referencing against available genetic databases and constructing a report based on interpretations in these databases. Variant annotations were made with
<a href="https://github.com/rkimoakbioinformatics/oakvar">OakVar</a>. Annotation databases that was used for report generating: cadd_exome, gnomAD, pubmed, clinpred, clinvar, ncbigene, omim, prec, provean, revel, sift, LongevityMap.
</p>
<p></p><div class="attention">
<p ><strong>Attention!</strong> The information provided is just for informational purposes. Its clinical implementation is possible just after consulting your healthcare practitioner. All drugs, vitamins and lifestyle changes may be prescribed just by your healthcare practitioner, based on clinical blood test results, family history etc. Genetical testing just provides additional information about possible health risk and risk management.
</p></div>
<p></p>
<p>The report consists of:</p>
<ul>
<li><a href="#variants" class="li1 second_li">Longevity variants</a></li>
<li><a href="#drugs" class="li1 third_li">Longevity drugs</a></li>
<li><a href="#cancer" class="li1 forth_li">Major risks</a></li>
</ul>
<p></p>
</div>
<h2 id="variants"> Longevity variants</h2>
<button class="accordion accordion0 accordion1 panel-variants module-button"><div></div> Description</button>
<div class="board variants panel panel-description">
<p></p>
<p>This report estimates how many significant longevity variations you have and whether its "a lot" or "not so" for your population. The data for this report is obtained mainly by studying centenarians’ genomes.
</p>
<p></p>
<p>The longevity variants report is based on 1900 variants from LongevityMap (<a href="https://genomics.senescence.info/longevity/"> genomics.senescence.info/longevity </a>) and other data sources which are scored and prioritized according to multiple criteria. It also depends on ClinGene, dbSNP and ClinVar modules.</p>
<p></p>
<p>In the table you can see, how many significant for your population variants were found in your genome. Positively longevity-associated variants are marked with green, negatively associated - with red.
</p>
<p>We have analyzed genes that affect different longevity pathways in your genome. We have divided them according to the longevity pathways they contribute to. So you can see which of them “work well” and which do not so.</p>
<p>Longevity pathways encompass a fascinating realm of biological processes and signaling pathways that play a crucial role in regulating aging and lifespan. Recent advancements in our understanding of these pathways have yielded valuable insights, including the identification of specific genes that impact the aging process [PMID:<a href="https://pubmed.ncbi.nlm.nih.gov/33891896/">33891896</a>].</p>