diff --git a/src-docs/src/views/datagrid/datagrid.js b/src-docs/src/views/datagrid/datagrid.js
index d2780c5d3b5..b3d4d3a83b2 100644
--- a/src-docs/src/views/datagrid/datagrid.js
+++ b/src-docs/src/views/datagrid/datagrid.js
@@ -1,7 +1,6 @@
 import React, {
   Fragment,
   useCallback,
-  useEffect,
   useMemo,
   useState,
   createContext,
@@ -366,23 +365,8 @@ export default () => {
   ); // initialize to the full set of columns
 
   const renderCellValue = useMemo(() => {
-    return ({ rowIndex, columnId, setCellProps }) => {
+    return ({ rowIndex, columnId, CellProps }) => {
       const data = useContext(DataContext);
-      useEffect(() => {
-        if (columnId === 'amount') {
-          if (data.hasOwnProperty(rowIndex)) {
-            const numeric = parseFloat(
-              data[rowIndex][columnId].match(/\d+\.\d+/)[0],
-              10
-            );
-            setCellProps({
-              style: {
-                backgroundColor: `rgba(0, 255, 0, ${numeric * 0.0002})`,
-              },
-            });
-          }
-        }
-      }, [rowIndex, columnId, setCellProps, data]);
 
       function getFormatted() {
         return data[rowIndex][columnId].formatted
@@ -390,9 +374,31 @@ export default () => {
           : data[rowIndex][columnId];
       }
 
-      return data.hasOwnProperty(rowIndex)
+      const content = data.hasOwnProperty(rowIndex)
         ? getFormatted(rowIndex, columnId)
         : null;
+
+      // Apply custom background color to cells in the `amount` columns
+      let cellProps = undefined;
+      if (columnId === 'amount') {
+        const numeric = parseFloat(content.match(/\d+\.\d+/)[0], 10);
+        cellProps = (
+          <CellProps
+            props={{
+              style: {
+                backgroundColor: `rgba(0, 255, 0, ${numeric * 0.0002})`,
+              },
+            }}
+          />
+        );
+      }
+
+      return (
+        <>
+          {content}
+          {cellProps}
+        </>
+      );
     };
   }, []);
 
diff --git a/src/components/datagrid/body/__snapshots__/data_grid_cell.test.tsx.snap b/src/components/datagrid/body/__snapshots__/data_grid_cell.test.tsx.snap
index 3f57f59cf0a..d2cd2c8d1c4 100644
--- a/src/components/datagrid/body/__snapshots__/data_grid_cell.test.tsx.snap
+++ b/src/components/datagrid/body/__snapshots__/data_grid_cell.test.tsx.snap
@@ -1,5 +1,39 @@
 // Jest Snapshot v1, https://goo.gl/fbAQLP
 
+exports[`EuiDataGridCell componentDidUpdate handles the cell popover by forwarding the cell's DOM node and contents to the parent popover context 1`] = `
+Array [
+  <div
+    data-test-subj="popover-test"
+  >
+    <div>
+      <button
+        data-datagrid-interactable="true"
+      >
+        hello
+      </button>
+      <button
+        data-datagrid-interactable="true"
+      >
+        world
+      </button>
+    </div>
+  </div>,
+  <div
+    class="euiPopoverFooter"
+  >
+    <div
+      class="euiFlexGroup euiFlexGroup--gutterSmall euiFlexGroup--directionRow euiFlexGroup--responsive"
+    >
+      <div
+        class="euiFlexItem"
+      >
+        <button />
+      </div>
+    </div>
+  </div>,
+]
+`;
+
 exports[`EuiDataGridCell renders 1`] = `
 <EuiDataGridCell
   colIndex={0}
@@ -83,6 +117,7 @@ exports[`EuiDataGridCell renders 1`] = `
         className="euiDataGridRowCell__expandContent"
       >
         <Memo()
+          CellProps={[Function]}
           colIndex={0}
           columnId="someColumn"
           isDefinedHeight={false}
@@ -131,6 +166,7 @@ exports[`EuiDataGridCell renders 1`] = `
             style={Object {}}
           >
             <renderCellValue
+              CellProps={[Function]}
               columnId="someColumn"
               data-test-subj="cell-content"
               isDetails={false}
@@ -167,37 +203,3 @@ exports[`EuiDataGridCell renders 1`] = `
   </div>
 </EuiDataGridCell>
 `;
-
-exports[`EuiDataGridCell componentDidUpdate handles the cell popover by forwarding the cell's DOM node and contents to the parent popover context 1`] = `
-Array [
-  <div
-    data-test-subj="popover-test"
-  >
-    <div>
-      <button
-        data-datagrid-interactable="true"
-      >
-        hello
-      </button>
-      <button
-        data-datagrid-interactable="true"
-      >
-        world
-      </button>
-    </div>
-  </div>,
-  <div
-    class="euiPopoverFooter"
-  >
-    <div
-      class="euiFlexGroup euiFlexGroup--gutterSmall euiFlexGroup--directionRow euiFlexGroup--responsive"
-    >
-      <div
-        class="euiFlexItem"
-      >
-        <button />
-      </div>
-    </div>
-  </div>,
-]
-`;
diff --git a/src/components/datagrid/body/data_grid_cell.tsx b/src/components/datagrid/body/data_grid_cell.tsx
index 4826891a3fa..812333d2f59 100644
--- a/src/components/datagrid/body/data_grid_cell.tsx
+++ b/src/components/datagrid/body/data_grid_cell.tsx
@@ -9,6 +9,7 @@
 import classNames from 'classnames';
 import React, {
   Component,
+  createContext,
   createRef,
   FocusEvent,
   FunctionComponent,
@@ -17,6 +18,8 @@ import React, {
   KeyboardEvent,
   memo,
   MutableRefObject,
+  useContext,
+  useEffect,
 } from 'react';
 import { createPortal } from 'react-dom';
 import tabbable from 'tabbable';
@@ -41,6 +44,7 @@ import { IS_JEST_ENVIRONMENT } from '../../../test';
 const EuiDataGridCellContent: FunctionComponent<
   EuiDataGridCellValueProps & {
     setCellProps: EuiDataGridCellValueElementProps['setCellProps'];
+    CellProps: typeof CellProps;
     setCellContentsRef: EuiDataGridCell['setCellContentsRef'];
     isExpanded: boolean;
     isDefinedHeight: boolean;
@@ -99,6 +103,22 @@ const EuiDataGridCellContent: FunctionComponent<
   }
 );
 
+const CellPropsContext = createContext<{
+  setCellProps: (props: HTMLAttributes<HTMLDivElement>) => void;
+}>({
+  setCellProps: () => {},
+});
+
+export const CellProps: FunctionComponent<{
+  props: HTMLAttributes<HTMLDivElement>;
+}> = ({ props }) => {
+  const { setCellProps } = useContext(CellPropsContext);
+  useEffect(() => {
+    setCellProps(props);
+  }, [setCellProps, props]);
+  return null;
+};
+
 export class EuiDataGridCell extends Component<
   EuiDataGridCellProps,
   EuiDataGridCellState
@@ -469,6 +489,7 @@ export class EuiDataGridCell extends Component<
               isExpandable={true}
               isExpanded={true}
               setCellProps={this.setCellProps}
+              CellProps={CellProps}
               isDetails={true}
             />
           </PopoverContent>
@@ -599,6 +620,7 @@ export class EuiDataGridCell extends Component<
     const cellContentProps = {
       ...rest,
       setCellProps: this.setCellProps,
+      CellProps,
       column,
       columnType: columnType,
       isExpandable,
@@ -668,32 +690,34 @@ export class EuiDataGridCell extends Component<
     }
 
     const content = (
-      <div
-        role="gridcell"
-        tabIndex={
-          this.state.isFocused && !this.state.disableCellTabIndex ? 0 : -1
-        }
-        ref={this.cellRef}
-        {...cellProps}
-        data-test-subj="dataGridRowCell"
-        // Data attributes to help target specific cells by either data or current cell location
-        data-gridcell-column-id={this.props.columnId} // Static column ID name, not affected by column order
-        data-gridcell-column-index={this.props.colIndex} // Affected by column reordering
-        data-gridcell-row-index={this.props.rowIndex} // Index from data, not affected by sorting or pagination
-        data-gridcell-visible-row-index={this.props.visibleRowIndex} // Affected by sorting & pagination
-        data-gridcell-id={`${this.props.colIndex},${this.props.rowIndex}`} // TODO: Deprecate in favor of the above 4 data attrs
-        onKeyDown={handleCellKeyDown}
-        onFocus={this.onFocus}
-        onMouseEnter={() => {
-          this.setState({ enableInteractions: true });
-        }}
-        onMouseLeave={() => {
-          this.setState({ enableInteractions: false });
-        }}
-        onBlur={this.onBlur}
-      >
-        {innerContent}
-      </div>
+      <CellPropsContext.Provider value={{ setCellProps: this.setCellProps }}>
+        <div
+          role="gridcell"
+          tabIndex={
+            this.state.isFocused && !this.state.disableCellTabIndex ? 0 : -1
+          }
+          ref={this.cellRef}
+          {...cellProps}
+          data-test-subj="dataGridRowCell"
+          // Data attributes to help target specific cells by either data or current cell location
+          data-gridcell-column-id={this.props.columnId} // Static column ID name, not affected by column order
+          data-gridcell-column-index={this.props.colIndex} // Affected by column reordering
+          data-gridcell-row-index={this.props.rowIndex} // Index from data, not affected by sorting or pagination
+          data-gridcell-visible-row-index={this.props.visibleRowIndex} // Affected by sorting & pagination
+          data-gridcell-id={`${this.props.colIndex},${this.props.rowIndex}`} // TODO: Deprecate in favor of the above 4 data attrs
+          onKeyDown={handleCellKeyDown}
+          onFocus={this.onFocus}
+          onMouseEnter={() => {
+            this.setState({ enableInteractions: true });
+          }}
+          onMouseLeave={() => {
+            this.setState({ enableInteractions: false });
+          }}
+          onBlur={this.onBlur}
+        >
+          {innerContent}
+        </div>
+      </CellPropsContext.Provider>
     );
 
     return rowManager && !IS_JEST_ENVIRONMENT
diff --git a/src/components/datagrid/data_grid_types.ts b/src/components/datagrid/data_grid_types.ts
index a84d03a0ead..eebf53eb94f 100644
--- a/src/components/datagrid/data_grid_types.ts
+++ b/src/components/datagrid/data_grid_types.ts
@@ -18,6 +18,7 @@ import {
   Dispatch,
   SetStateAction,
   MutableRefObject,
+  FunctionComponent,
 } from 'react';
 import {
   VariableSizeGridProps,
@@ -389,6 +390,10 @@ export interface EuiDataGridCellValueElementProps {
    * it's best to wrap calls to `setCellProps` in a `useEffect` hook
    */
   setCellProps: (props: CommonProps & HTMLAttributes<HTMLDivElement>) => void;
+  /**
+   * React component that can be used to specific custom props & attributes on the cell's wrapping `div` element
+   */
+  CellProps: FunctionComponent<{ props: HTMLAttributes<HTMLDivElement> }>;
   /**
    * whether or not the cell is expandable, comes from the #EuiDataGridColumn `isExpandable` which defaults to `true`
    */
diff --git a/src/components/datagrid/utils/in_memory.tsx b/src/components/datagrid/utils/in_memory.tsx
index ef979fa2cb0..0522344cba6 100644
--- a/src/components/datagrid/utils/in_memory.tsx
+++ b/src/components/datagrid/utils/in_memory.tsx
@@ -24,6 +24,7 @@ import {
   EuiDataGridInMemoryRendererProps,
   EuiDataGridCellValueElementProps,
 } from '../data_grid_types';
+import { CellProps } from '../body/data_grid_cell';
 
 /**
  * inMemory values hook
@@ -124,6 +125,7 @@ export const EuiDataGridInMemoryRenderer: FunctionComponent<EuiDataGridInMemoryR
                   rowIndex={i}
                   columnId={column.id}
                   setCellProps={noop}
+                  CellProps={CellProps}
                   isExpandable={isExpandable}
                   isExpanded={false}
                   isDetails={false}