diff --git a/crates/artifacts/vyper/src/settings.rs b/crates/artifacts/vyper/src/settings.rs
index 3653b0a13..f162d2871 100644
--- a/crates/artifacts/vyper/src/settings.rs
+++ b/crates/artifacts/vyper/src/settings.rs
@@ -13,6 +13,7 @@ pub const VYPER_BERLIN: Version = Version::new(0, 3, 0);
 pub const VYPER_PARIS: Version = Version::new(0, 3, 7);
 pub const VYPER_SHANGHAI: Version = Version::new(0, 3, 8);
 pub const VYPER_CANCUN: Version = Version::new(0, 3, 8);
+pub const VYPER_PRAGUE: Version = Version::new(0, 4, 3);
 
 const VYPER_0_4: Version = Version::new(0, 4, 0);
 
@@ -126,7 +127,9 @@ impl VyperSettings {
     /// Adjusts the EVM version based on the compiler version.
     pub fn normalize_evm_version(&mut self, version: &Version) {
         if let Some(evm_version) = &mut self.evm_version {
-            *evm_version = if *evm_version >= EvmVersion::Cancun && *version >= VYPER_CANCUN {
+            *evm_version = if *evm_version >= EvmVersion::Prague && *version >= VYPER_PRAGUE {
+                EvmVersion::Prague
+            } else if *evm_version >= EvmVersion::Cancun && *version >= VYPER_CANCUN {
                 EvmVersion::Cancun
             } else if *evm_version >= EvmVersion::Shanghai && *version >= VYPER_SHANGHAI {
                 EvmVersion::Shanghai
diff --git a/crates/compilers/tests/project.rs b/crates/compilers/tests/project.rs
index 334d43834..fcae49532 100644
--- a/crates/compilers/tests/project.rs
+++ b/crates/compilers/tests/project.rs
@@ -60,7 +60,7 @@ pub static VYPER: LazyLock<Vyper> = LazyLock::new(|| {
             return Vyper::new(&path).unwrap();
         }
 
-        let base = "https://github.com/vyperlang/vyper/releases/download/v0.4.0/vyper.0.4.0+commit.e9db8d9f";
+        let base = "https://github.com/vyperlang/vyper/releases/download/v0.4.3/vyper.0.4.3+commit.bff19ea2";
         let url = format!(
             "{base}.{}",
             match platform() {