diff --git a/docs/publications/BioHackrXiv/annotation.png b/docs/publications/BioHackrXiv/annotation.png new file mode 100644 index 00000000..6664d268 Binary files /dev/null and b/docs/publications/BioHackrXiv/annotation.png differ diff --git a/docs/publications/BioHackrXiv/flowchart.png b/docs/publications/BioHackrXiv/flowchart.png new file mode 100644 index 00000000..40829e66 Binary files /dev/null and b/docs/publications/BioHackrXiv/flowchart.png differ diff --git a/docs/publications/BioHackrXiv/itable.png b/docs/publications/BioHackrXiv/itable.png new file mode 100644 index 00000000..0384af6e Binary files /dev/null and b/docs/publications/BioHackrXiv/itable.png differ diff --git a/docs/publications/BioHackrXiv/paper.bib b/docs/publications/BioHackrXiv/paper.bib new file mode 100644 index 00000000..4af211b0 --- /dev/null +++ b/docs/publications/BioHackrXiv/paper.bib @@ -0,0 +1,167 @@ +@article{10.1093/nar/gkac247, + author = {The Galaxy Community}, + title = "{The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update}", + journal = {Nucleic Acids Research}, + volume = {50}, + number = {W1}, + pages = {W345-W351}, + year = {2022}, + month = {04}, + abstract = "{Galaxy is a mature, browser accessible workbench for scientific computing. It enables scientists to share, analyze and visualize their own data, with minimal technical impediments. A thriving global community continues to use, maintain and contribute to the project, with support from multiple national infrastructure providers that enable freely accessible analysis and training services. The Galaxy Training Network supports free, self-directed, virtual training with \\>230 integrated tutorials. Project engagement metrics have continued to grow over the last 2 years, including source code contributions, publications, software packages wrapped as tools, registered users and their daily analysis jobs, and new independent specialized servers. Key Galaxy technical developments include an improved user interface for launching large-scale analyses with many files, interactive tools for exploratory data analysis, and a complete suite of machine learning tools. Important scientific developments enabled by Galaxy include Vertebrate Genome Project (VGP) assembly workflows and global SARS-CoV-2 collaborations.}", + issn = {0305-1048}, + doi = {10.1093/nar/gkac247}, + url = {https://doi.org/10.1093/nar/gkac247}, + eprint = {https://academic.oup.com/nar/article-pdf/50/W1/W345/45189566/gkac247.pdf}, +} + +@article{rost2016openms, + title={OpenMS: a flexible open-source software platform for mass spectrometry data analysis}, + author={R{\"o}st, Hannes L and Sachsenberg, Timo and Aiche, Stephan and Bielow, Chris and Weisser, Hendrik and Aicheler, Fabian and Andreotti, Sandro and Ehrlich, Hans-Christian and Gutenbrunner, Petra and Kenar, Erhan and others}, + journal={Nature Methods}, + doi={10.1038/nmeth.3959}, + volume={13}, + number={9}, + pages={741--748}, + year={2016}, + publisher={Nature Publishing Group} +} + +@article{doi:10.1128/AEM.01541-09, +author = {Patrick D. Schloss and Sarah L. Westcott and Thomas Ryabin and Justine R. Hall and Martin Hartmann and Emily B. Hollister and Ryan A. Lesniewski and Brian B. Oakley and Donovan H. Parks and Courtney J. Robinson and Jason W. Sahl and Blaz Stres and Gerhard G. Thallinger and David J. Van Horn and Carolyn F. Weber}, +title = {Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities}, +journal = {Applied and Environmental Microbiology}, +volume = {75}, +number = {23}, +pages = {7537-7541}, +year = {2009}, +doi = {10.1128/AEM.01541-09}, +URL = {https://journals.asm.org/doi/abs/10.1128/aem.01541-09}, +eprint = {https://journals.asm.org/doi/pdf/10.1128/aem.01541-09}, +abstract = { mothur aims to be a comprehensive software package that allows users to use a single piece of software to analyze community sequence data. It builds upon previous tools to provide a flexible and powerful software package for analyzing sequencing data. As a case study, we used mothur to trim, screen, and align sequences; calculate distances; assign sequences to operational taxonomic units; and describe the α and β diversity of eight marine samples previously characterized by pyrosequencing of 16S rRNA gene fragments. This analysis of more than 222,000 sequences was completed in less than 2 h with a laptop computer. } +} + +@article{black2021edam, + title={EDAM: The bioscientific data analysis ontology (update 2021)[version 1; not peer reviewed]}, + author={Black, Melissa and Lamothe, Lucie and Eldakroury, Hager and Kierkegaard, Mads and Priya, Ankita and Machinda, Anne and Singh Khanduja, Uttam and Patoliya, Drashti and Rathi, Rashika and Che Nico, Tawah Peggy and others}, + year={2022}, + doi={10.7490/f1000research.1118900.1}, + journal={F1000Research}, + publisher={F1000} +} + +@article{biotoolsSchema, + author = {Ison, Jon and Ienasescu, Hans and Rydza, Emil and Chmura, Piotr and Rapacki, Kristoffer and Gaignard, Alban and Schwämmle, Veit and van Helden, Jacques and Kala{\v{s}}, Mat{\'u}{\v{s}} and M{\'e}nager, Herv{\'e}}, + title = "{biotoolsSchema: a formalized schema for bioinformatics software description}", + journal = {GigaScience}, + volume = {10}, + number = {1}, + pages = {giaa157}, + year = {2021}, + month = {01}, + issn = {2047-217X}, + doi = {10.1093/gigascience/giaa157}, + url = {https://doi.org/10.1093/gigascience/giaa157}, + eprint = {https://academic.oup.com/gigascience/article-pdf/10/1/giaa157/36126150/giaa157.pdf}, +} + +@article{Ison2019, + title = {The bio.tools registry of software tools and data resources for the life sciences}, + volume = {20}, + ISSN = {1474-760X}, + url = {http://doi.org/10.1186/s13059-019-1772-6}, + DOI = {10.1186/s13059-019-1772-6}, + number = {1}, + journal = {Genome Biology}, + publisher = {Springer Science and Business Media LLC}, + author = {Ison, Jon and Ienasescu, Hans and Chmura, Piotr and Rydza, Emil and M{\'e}nager, Herv{\'e} and Kala{\v{s}}, Mat{\'u}{\v{s}} and Schw\"{a}mmle, Veit and Gr\"{u}ning, Bj\"{o}rn and Beard, Niall and Lopez, Rodrigo and Duvaud, Severine and Stockinger, Heinz and Persson, Bengt and Vařeková, Radka Svobodová and Raček, Tomáš and Vondrášek, Jiří and Peterson, Hedi and Salumets, Ahto and Jonassen, Inge and Hooft, Rob and Nyr\"{o}nen, Tommi and Valencia, Alfonso and Capella, Salvador and Gelpí, Josep and Zambelli, Federico and Savakis, Babis and Leskošek, Brane and Rapacki, Kristoffer and Blanchet, Christophe and Jimenez, Rafael and Oliveira, Arlindo and Vriend, Gert and Collin, Olivier and van Helden, Jacques and Løngreen, Peter and Brunak, Søren}, + year = {2019}, + month = aug +} + +@article {Bray2022.03.13.483965, + author = {Simon Bray and Matthias Bernt and Nicola Soranzo and Marius van den Beek and B{\'e}r{\'e}nice Batut and Helena Rasche and Martin {\v C}ech and Peter Cock and Anton Nekrutenko and Bj{\"o}rn Gr{\"u}ning and John Chilton}, + title = {Planemo: a command-line toolkit for developing, deploying, and executing scientific data analyses}, + elocation-id = {2022.03.13.483965}, + year = {2022}, + doi = {10.1101/2022.03.13.483965}, + publisher = {Cold Spring Harbor Laboratory}, + abstract = {There are thousands of well-maintained high-quality open-source software utilities for all aspects of scientific data analysis. For over a decade, the Galaxy Project has been providing computational infrastructure and a unified user interface for these tools to make them accessible to a wide range of researchers. In order to streamline the process of integrating tools and constructing workflows as much as possible, we have developed Planemo, a software development kit for tool and workflow developers and Galaxy power users. Here we outline Planemo{\textquoteright}s implementation and describe its broad range of functionality for designing, testing and executing Galaxy tools, workflows and training material. In addition, we discuss the philosophy underlying Galaxy tool and workflow development, and how Planemo encourages the use of development best practices, such as test-driven development, by its users, including those who are not professional software developers. Planemo is a mature project widely used within the Galaxy community which has been downloaded over 80,000 times.Competing Interest StatementThe authors have declared no competing interest.}, + URL = {https://www.biorxiv.org/content/early/2022/03/14/2022.03.13.483965}, + eprint = {https://www.biorxiv.org/content/early/2022/03/14/2022.03.13.483965.full.pdf}, + journal = {bioRxiv} +} + +@misc{datatables, + title = {{DataTables} {\textbar} {Table} plug-in for {jQuery}}, + url = {https://datatables.net/}, + urldate = {2023-11-28}, +} + +@misc{conda, + title = {Anaconda Software Distribution}, + url = {https://anaconda.com}, + urldate = {2016-11-01} +} + +@article{edamBrowser, doi = {10.21105/joss.00698}, url = {https://doi.org/10.21105/joss.00698}, year = {2018}, publisher = {The Open Journal}, volume = {3}, number = {27}, pages = {698}, author = {Bryan Brancotte and Christophe Blanchet and Hervé Ménager}, title = {A reusable tree-based web-visualization to browse EDAM ontology, and contribute to it.}, journal = {Journal of Open Source Software} } + +@misc{edamBrowserCode + doi = {10.5281/zenodo.5808818}, + url = {https://zenodo.org/doi/10.5281/zenodo.5808818}, + author = {Eldakroury, Hager and Dhamija, Sakshi and Rathi, Rashika and Patoliya, Drashti and Nkwuda, Sunday Cletus and Singh, Guneet and Yadav, Pooja and D'oleo, Kelly and Cherop, Marlene and Che Nico, Tawah Peggy and Kalaš, Matúš and Ménager, Hervé and Brancotte, Bryan}, + keywords = {Ontology browser, Biosciences, Imaging, Machine learning, Domain ontology, EDAM}, + language = {en}, + title = {EDAM Browser 2.0.0: Browsing multiple versions of EDAM}, + publisher = {Zenodo}, + year = {2021}, + copyright = {MIT License} +} + +@article{batut_community-driven_2018, + title = {Community-{Driven} {Data} {Analysis} {Training} for {Biology}}, + volume = {6}, + issn = {24054712}, + url = {https://linkinghub.elsevier.com/retrieve/pii/S2405471218302308}, + doi = {10.1016/j.cels.2018.05.012}, + language = {en}, + number = {6}, + urldate = {2024-02-26}, + journal = {Cell Systems}, + author = {Batut, Bérénice and Hiltemann, Saskia and Bagnacani, Andrea and Baker, Dannon and Bhardwaj, Vivek and Blank, Clemens and Bretaudeau, Anthony and Brillet-Guéguen, Loraine and Čech, Martin and Chilton, John and Clements, Dave and Doppelt-Azeroual, Olivia and Erxleben, Anika and Freeberg, Mallory Ann and Gladman, Simon and Hoogstrate, Youri and Hotz, Hans-Rudolf and Houwaart, Torsten and Jagtap, Pratik and Larivière, Delphine and Le Corguillé, Gildas and Manke, Thomas and Mareuil, Fabien and Ramírez, Fidel and Ryan, Devon and Sigloch, Florian Christoph and Soranzo, Nicola and Wolff, Joachim and Videm, Pavankumar and Wolfien, Markus and Wubuli, Aisanjiang and Yusuf, Dilmurat and Taylor, James and Backofen, Rolf and Nekrutenko, Anton and Grüning, Björn}, + month = jun, + year = {2018}, + pages = {752--758.e1}, +} + +@Article{elixirBiodiversity, +AUTHOR = { Waterhouse, RM and Adam-Blondon, AF and Balech, B and Barta, E and Heil, KF and Hughes, GM and Jermiin, LS and Kala\v{s}, M and Lanfear, J and Pafilis, E and Papageorgiou, AC and Psomopoulos, F and Raes, N and Burgin, J and Gabaldón, T}, +TITLE = {{The ELIXIR Biodiversity Community: Understanding short- and long-term changes in biodiversity [version 1; peer review: 1 approved with reservations, 1 not approved]}}, +JOURNAL = {F1000Research}, +VOLUME = {12}, +YEAR = {2023}, +NUMBER = {499}, +DOI = {10.12688/f1000research.133724.1} +} + +@misc{RSEc, + doi = {10.7490/f1000research.1119604.1}, + url = {https://f1000research.com/slides/12-1044}, + author = {Ienasescu, Hans and Capella-Gutiérrez, Salvador and Coppens, Frederik and Fernández, José María and Gaignard, Alban and Goble, Carole and Gr\"{u}ning, Bj\"{o}rn and Gustafsson, Johan and Gelpi, Josep Ll and Harrow, Jennifer and Manos, Steven and Miura, Kota and M\"{o}ller, Steffen and Owen, Stuart and Paul-Gilloteaux, Perrine and Peterson, Hedi and Pitoulias, Manthos and Tedds, Jonathan and Repchevsky, Dmitri and Zambelli, Federico and Zharkov, Oleg and Kala\v{s}, Mat\'{u}\v{s} and Ménager, Hervé}, + title = {The ELIXIR research software ecosystem: an open software metadata commons (BOSC track) [version 1; not peer reviewed]}, + publisher = {F1000 Research}, + year = {2023} +} + +@article{bioimageWorkflows, + title = {Bioimage analysis workflows: community resources to navigate through a complex ecosystem}, + volume = {10}, + ISSN = {2046-1402}, + url = {https://doi.org/10.12688/f1000research.52569.1}, + DOI = {10.12688/f1000research.52569.1}, + journal = {F1000Research}, + publisher = {F1000 Research Ltd}, + author = {Paul-Gilloteaux, Perrine and Tosi, Sébastien and Hériché, Jean-Karim and Gaignard, Alban and Ménager, Hervé and Marée, Raphaël and Baecker, Volker and Klemm, Anna and Kalaš, Matúš and Zhang, Chong and Miura, Kota and Colombelli, Julien}, + year = {2021}, + month = apr, + pages = {320} +} diff --git a/docs/publications/BioHackrXiv/paper.md b/docs/publications/BioHackrXiv/paper.md new file mode 100644 index 00000000..8eef0db3 --- /dev/null +++ b/docs/publications/BioHackrXiv/paper.md @@ -0,0 +1,215 @@ +--- +title: 'How to increase the findability, visibility, and impact of Galaxy tools for your scientific community' +title_short: 'BH23EU project 25: Finding Galaxy tools' +tags: + - Findability + - Galaxy + - Community-specific Galaxy tools + - Tools + - EDAM + - bio.tools + - Metadata +authors: + - name: Paul Zierep + orcid: + affiliation: 1 + - name: Bérénice Batut + orcid: 0000-0001-9852-1987 + affiliation: 1, 2 + - name: Nicola Soranzo + orcid: 0000-0003-3627-5340 + affiliation: 3 + - name: Matúš Kalaš + orcid: 0000-0002-1509-4981 + affiliation: 4 + - name: Ove Johan Ragnar Gustafsson + orcid: 0000-0002-2977-5032 + affiliation: 5 + - name: Engy Nasr + orcid: 0000-0001-9047-4215 + affiliation: 1 + - name: Tunc Kayikcioglu + orcid: 0000-0003-2205-8062 + affiliation: 1 + - name: Joseph Wang + orcid: + affiliation: 6 +affiliations: + - name: Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg, Germany + index: 1 + - name: Institut Français de Bioinformatique, CNRS UAR 3601, Évry, France & Mésocentre Clermont-Auvergne, Université Clermont Auvergne, Aubiere, France + index: 2 + - name: Earlham Institute, Norwich Research Park, Norwich, UK + index: 3 + - name: Department of Informatics, University of Bergen, Norway; and ELIXIR Norway + index: 4 + - name: Australian BioCommons, University of Melbourne, Melbourne, Victoria, Australia + index: 5 + - name: Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, Queensland, Australia + index: 6 +date: 23 February 2024 +bibliography: paper.bib +event: BH23EU +biohackathon_name: "BioHackathon Europe 2023" +biohackathon_url: "https://biohackathon-europe.org/" +biohackathon_location: "Barcelona, Spain, 2023" +group: Project 25 - Increasing the findability, visibility, and impact of Galaxy tools for specialised scientific communities +git_url: https://github.com/galaxyproject/galaxy_tool_metadata_extractor/tree/e604ffd9866f9c32f797ceee45062b4d6f2a1513/docs/publications/BioHackrXiv +authors_short: Paul Zierep, Bérénice Batut, \emph{et al.} +--- + + +# Introduction or Background + +Galaxy[@citesAsAuthority:10.1093/nar/gkac247] is a web-based analysis platform offering almost 10,000 different tools, which are developed in various GitHub repositories. +Furthermore, the Galaxy community embraces granular implementation of software tools as sub-modules. +In practice, this means that tool suites are separated into sets of Galaxy tools, also known as Galaxy wrappers, that contain functionality of a corresponding sub-component. +Some key examples of tool suites include [Mothur](https://bio.tools/mothur)[@citesAsAuthority:doi:10.1128/AEM.01541-09] and [OpenMS](https://bio.tools/openms)[@citesAsAuthority:rost2016openms], which translate to tens and even hundreds of Galaxy tools. +While granularity supports the composability of tools into diverse purpose-specific workflows, this decentralised development and modular architecture can make it difficult for Galaxy users to find and use tools. +It may also result in Galaxy tool-wrapper developers duplicating efforts by simultaneously wrapping the same software. +This is further complicated by the scarcity of tool metadata, which prevents filtering of tools as relevant for a specific scientific community or domain, and makes it impossible to employ advanced filtering by ontology terms like the ones from EDAM[@citesAsAuthority:black2021edam]. +The final challenge is also an opportunity: the global and cross-domain nature of Galaxy means that it is a big community. +Solving the visibility of tools across this "ecosystem", and the resulting benefits, are far-reaching for the global collaborative development of data-analysis tools and workflows. + +To provide the scientific community with a comprehensive list of annotated Galaxy tools, +we developed a pipeline at the [ELIXIR BioHackathon Europe 2023](https://2023.biohackathon-europe.org) that collects Galaxy wrappers from a list of GitHub repositories and automatically extracts their metadata (including Conda version [@citesAsAuthority:conda], bio.tools identifier[@citesAsAuthority:biotoolsSchema, @usesDataFrom:Ison2019], BIII identifier[@citesAsAuthority:bioimageWorkflows], and EDAM annotations). +The workflow also queries the availability of the tools from the three main Galaxy servers (_usegalaxy.*_) as well as usage statistics from [usegalaxy.eu](https://usegalaxy.eu) (Note: the other main Galaxy servers, [usegalaxy.org](https://usagalaxy.org) and [usegalaxy.org.au](https://usagalaxy.org.au), will be queried for usage statistics in coming updates). + +Crucially, the pipeline can filter its inputs to only include tools that are relevant to a specific research community. +Based on the selected filters, a community-specific interactive table is generated that can be embedded, _e.g._ into the respective [Galaxy Hub](https://galaxyproject.org/) webpage or [Galaxy subdomain](https://galaxyproject.org/eu/subdomains/). +This table allows further filtering and searching for fine-grained tool selection. +The pipeline is fully automated and executes on a weekly basis. +Any scientific community can apply the pipeline to create a table specific to their needs. + +An interactive table that presents metadata is only as useful as the metadata annotations it is capturing. +To improve the metadata coverage for the interactive table, the project also directly addressed the quality of tool annotations in bio.tools for the [microGalaxy community](https://galaxyproject.org/community/sig/microbial/): +a community with a focus on tools related to microbial research. + +Annotation guidelines were established for this purpose, the process of updating Galaxy tool wrappers to include bio.tools identifiers was started and the outcome of these activities was evaluated using a crowdsourced approach. During the BioHackathon Europe 2023 week, the annotation practices were applied to the tools selected from the microGalaxy community. +This effort allowed the team to connect more than 50 tools to their respective bio.tools entry, update the registry entry, and collectively peer-review the results. + +The established pipeline and the annotation guidelines can support any scientific community to make their Galaxy tools more findable, visible, comparable, understandable, and accessible. +Here, we describe the methods and processes that resulted from this project, and highlight how this will now allow the microGalaxy community to confidently navigate an ever-expanding landscape of research software in the Galaxy framework. + + +# Methods + +## Domain-specific interactive tools table + +To create the domain-specific interactive tools table, Galaxy tool-wrapper suites are first parsed from across multiple GitHub repositories. +In effect, the repositories monitored by the planemo-monitor[@citesAsAuthority:Bray2022.03.13.483965] are scraped using a custom script. +The planemo-monitor is part of the Galaxy tool-update infrastructure, and keeps track of the most up-to-date tool development repositories. + +Metadata is extracted from each parsed tool-wrapper suite. +This includes: wrapper suite ID, scientific category, Bioconda dependency, and a repository URL from bio.tools. +As a tool suite can be composed of multiple individual tools, the tool IDs for each tool are also extracted. +The bio.tools reference is used to request metadata annotations via the bio.tools API, including bio.tools description and functionality annotation using EDAM ontology concepts[@usesDataFrom:black2021edam]. +The latest Conda package version is retrieved via the Bioconda API and compared to the Galaxy tool version to determine the tool’s update state (_i.e._ to update, or no update required). + +The Galaxy API is used to query if each tool is installed on one of the three usegalaxy.* Galaxy servers ([usegalaxy.eu](https://usegalaxy.eu/), [usegalaxy.org](https://usegalaxy.org/), [usegalaxy.org.au](https://usegalaxy.org.au/)). Furthermore, the tool usage statistics can be retrieved from an SQL query that needs to be executed by Galaxy administrators. +The query used in the current implementation shows the overall tool usage as well as how many users executed a tool in the last 2 years on the European server ([usegalaxy.eu](https://usegalaxy.eu/)). + +The output of the pipeline is a table that combines Galaxy wrappers with their metadata. +The complete table can then be filtered to include only tools with relevance for specific communities. +The initial filtering step is based on the scientific category, which is defined for every Galaxy tool wrapper. +These categories are high-level and cannot distinguish between specific tool functions. +However, they allow for the isolation of a subgroup of the initial table for further curation. +The filtered table can then be manually curated by community curators. +This curation step involves annotating which of the extracted tools should be kept in the final table. +Curators can use the EDAM annotations and tool descriptions to assist with this curation step. +The `to keep` labels for each tool are stored to reduce the replication of effort even further. +The practical outcome is that for repeat executions of the workflow, only new tools require curation. + +The curated tools are transformed into an interactive web table using the data tables framework[@datatables]. +The table is hosted on GitHub and deployed via GitHub pages for each community. +This implementation enables complex queries and filtering without the need for a database backend. +The table can be embedded in any website via an iframe: examples include the Galaxy community [Hub page for microGalaxy](https://galaxyproject.org/community/sig/microbial#tools) or the [microGalaxy subdomain](https://microgalaxy.usegalaxy.eu/). +Furthermore, a word cloud based on the usage statistics of the tools is created. + +The workflow is run weekly via GitHub Actions continuous integration, providing an up-to-date table for each community. +The usage of an iframe enables updates for the table to propagate automatically to any website where it is deployed. + +Any Galaxy community can use the pipeline by adding a folder in the [project GitHub repository](https://github.com/galaxyproject/galaxy_tool_extractor/). +To initialise the pipeline for a new community you need to add a new subfolder of `data/communities/` , and inside it add a file called 'categories' with a list of Galaxy ToolShed (**cite** doi:10.1186/gb4161 ) categories. +Additionally, tools that should be excluded or included after filtering, can be added to respective files as well. +A working example of the community configuration files can be found in the folder for the microGalaxy community. + +![Workflow of the Galaxy tool metadata extractor pipeline. Tool wrappers are parsed from different repositories and additional metadata is retrieved from bio.tools, Bioconda, and the main public Galaxy servers. Upon filtering and manual curation of the data for specific scientific communities, the data is transformed into interactive web tables and a tool usage statistics-based word cloud, that can be integrated into any website. \label{metadata_extractor_pipeline}](./figures/flowchart.png) + + +## Annotation workflow + +The annotation process begins by selecting a tool from a Galaxy community. +This step can make use of the interactive table created by the Galaxy tool extractor scripts presented above. +A curator then needs to visit the development repository of the Galaxy tool wrapper and search the XML file for a bio.tools xref snippet (Figure \ref{xref_snippet}). + +![xref snippet example for a Galaxy tool wrapper that contains the tool [Racon](https://bio.tools/Racon). \label{xref_snippet}](./xref.png) + +bio.tools is then checked to confirm that a bio.tools identifier does, or does not, exist. +The reason for this is that even if a bio.tools identifier exists in a tool wrapper, it may not necessarily exist in bio.tools. +This is an observation based on real-world annotation errors and serves as a useful supporting step to improve Galaxy wrapper annotations and the completeness of the bio.tools registry. +In addition, if a bio.tools identifier is not included in the wrapper, this does not mean that there is not a bio.tools identifier available in the registry. + +There are then two curation paths to choose from, depending on whether a bio.tools identifier exists in the XML wrapper. In both cases, if no bio.tools entry exists, a new entry should be created and updated using the bio.tools wizard. The creation and update of an entry includes adding concepts from the EDAM ontology. This annotation process can be simplified through the use of [EDAM Browser](https://edamontology.github.io/edam-browser/)[@citesAsAuthority:edamBrowser, @citesAsAuthority:edamBrowserCode]. + +In the case where no bio.tools identifier exists in the Galaxy XML wrapper, the development repository needs to be forked and a new branch created. +A new xref snippet can then be added, and a pull request opened against the original repository. + +Figure \ref{annotation_workflow} shows a step-by-step breakdown of the above process. + +![Step-by-step workflow for systematically improving metadata annotations across bio.tools registry entries and Galaxy tool wrappers. After selecting a Galaxy tool and checking for the presence of a bio.tools ID in its XML file, a curator needs to review bio.tools, create a new bio.tools entry (if needed), and then ensure that both this entry and the Galaxy tool XML file are up-to-date. Updating bio.tools makes use of the registry wizard, and updating a Galaxy tool wrapper to include a bio.tools xref snippet requires a pull request against the development repository. \label{annotation_workflow}](./annotation.png) + + +# Outcomes and results + +There were multiple concrete outcomes from this BioHackathon project, including the ability to create interactive Galaxy tools tables as needed for scientific communities, a process for updating bio.tools, in-development Galaxy Training Network (GTN) tutorials[@citesAsAuthority:batut_community-driven_2018] describing this process, and an update to the [Galaxy IUC](https://galaxyproject.org/iuc/) tool wrapping [standards](https://galaxy-iuc-standards.readthedocs.io/en/latest/index.html). +These are described in more detail below. + + +## Prototype interactive table for Galaxy communities + +The described workflow for the Galaxy tool metadata extractor (see Figure \ref{metadata_extractor_pipeline}) was successfully implemented ([GitHub repository](https://github.com/galaxyproject/galaxy_tool_extractor)) and could more then 1,300 Galaxy tool suites (see the [GitHub repository pages](https://galaxyproject.github.io/galaxy_tool_metadata_extractor) for an up-to-date table). +Of those tool suites, only 267 had a bio.tools identifier, which highlights the importance of performing the annotation process in parallel and complementing the tools with additional metadata. +An example view of the created interactive table is shown in Figure \ref{web_table}. +As mentioned above, the filtered table for the microGalaxy community has already been embedded in the [Hub page for microGalaxy](https://galaxyproject.org/community/sig/microbial#tools), as well as the dedicated [microGalaxy subdomain](https://microgalaxy.usegalaxy.eu/). +The process for creating a new interactive table for a community is currently being transformed into a GTN tutorial. + +![Screenshot of the interactive web table. The table provides comprehensive metadata for all Galaxy wrappers of a specific community and allows for custom searches based on logic filters over all columns. In the shown example, the user queries for all up-to-date tools that are annotated with an EDAM operation that includes "assembly". \label{web_table}](./figures/itable.png) + + +## bio.tools and EDAM annotations for microGalaxy community + +During the week of the BioHackathon, the microGalaxy community executed the annotation workflow as described in the Methods section (see also Figure \ref{annotation_workflow}). +The initial filtered tool table of the microGalaxy included 218 tool suites, of which 61 had corresponding bio.tools identifiers. +The progress of the work was tracked using a GitHub project board. +After the annotation process, the number of tools with bio.tools annotations was increased to 107. +The added annotations for each respective bio.tools entry were also collectively reviewed by the team. +A rerun of the Galaxy tool metadata extractor pipeline collected the additional information, and the metadata is now included in the interactive microGalaxy tool table. + + +## Training materials and updates to standards + +To provide the Galaxy research communities with simple and straightforward guide to annotating their respective tool stacks, the described annotation workflow is currently being transformed into a GTN tutorial. +The guidelines created were also used to update the [best practices for creating Galaxy tools of the IUC repository](https://galaxy-iuc-standards.readthedocs.io/en/latest/best_practices/tool_xml.html). + + +# Conclusion and outlook + +The project was able to successfully meet its aim of creating reusable prototypes and processes that make the richness of the Galaxy tools ecosystem more discoverable and understandable. +Central to this work was the Galaxy tool metadata extractor pipeline, which is currently generating comprehensive and interactive tabular summaries of Galaxy tools for the [microbial data](https://galaxyproject.org/community/sig/microbial/) and [image analysis](https://galaxyproject.org/use/imaging/) communities within Galaxy (with EU BioHackathon 2023 [Project 16](https://github.com/elixir-europe/biohackathon-projects-2023/tree/main/16)). The metadata extractor can be reused by any Galaxy group or community. For example, the [biodiversity and ecology](https://galaxyproject.org/use/ecology/) community will employ this pipeline in the near future[@citesAsAuthority:elixirBiodiversity]. +The generated tabular tool summary provides valuable information that extends beyond the use case of listing community tools. Therefore, an integration with the [Research Software Ecosystem (RSEc)](https://github.com/research-software-ecosystem/content)[@citeAsAuthority:RSEc] is currently being worked on. +Various updates of the Galaxy tool metadata extractor pipeline are also envisioned, such as the integration of comprehensive usage statistics for all large Galaxy servers, additional bio.tools metadata, and a user-friendly integration of manual curation steps. + +A set of updates to standards and processes was also created. +These will support the on-going growth of the metadata hosted by the interactive tables: primarily by helping communities to maintain and extend the annotations of Galaxy tool wrappers, and the bio.tools ecosystem on which these wrapper annotations depend. + + +# Acknowledgements + +This work was developed as part of BioHackathon Europe 2023. +This work was supported by [ELIXIR](https://elixir-europe.org), the research infrastructure for life science data. +This work was supported by the Australian BioCommons which is enabled by NCRIS via Bioplatforms Australia funding. + + +# References + diff --git a/docs/publications/BioHackrXiv/xref.png b/docs/publications/BioHackrXiv/xref.png new file mode 100644 index 00000000..7bce36c3 Binary files /dev/null and b/docs/publications/BioHackrXiv/xref.png differ diff --git a/results/imaging/index.html b/results/imaging/index.html index 192d81cf..b1cd7028 100644 --- a/results/imaging/index.html +++ b/results/imaging/index.html @@ -784,7 +784,6 @@ Image segmentation and object detection performance measures Image segmentation and object detection performance measures - segmetrics To update https://github.com/bmcv Imaging @@ -868,7 +867,6 @@ Globally optimal segmentation method based on superadditivity and deformable shape models for cell nuclei in fluorescence microscopy images SuperDSM is a globally optimal segmentation method based on superadditivity and deformable shape models for cell nuclei in fluorescence microscopy images and beyond. - superdsm Up-to-date https://github.com/bmcv Imaging diff --git a/results/imaging/tools.tsv b/results/imaging/tools.tsv index 4b0038db..6282f14a 100644 --- a/results/imaging/tools.tsv +++ b/results/imaging/tools.tsv @@ -1,58 +1,56 @@ -Galaxy wrapper id Total tool usage (usegalaxy.eu) No. of tool users (2022-2023) (usegalaxy.eu) Galaxy tool ids Description bio.tool id biii bio.tool name bio.tool description EDAM operation EDAM topic Status Source ToolShed categories ToolShed id Galaxy wrapper owner Galaxy wrapper source Galaxy wrapper version Conda id Conda version https://usegalaxy.org https://usegalaxy.org.au https://usegalaxy.eu Reviewed To keep -2d_auto_threshold 6541.0 39.0 ip_threshold Automatic thresholding scikit-image scikit-image scikit-image Scikit-image contains image processing algorithms for SciPy, including IO, morphology, filtering, warping, color manipulation, object detection, etc. Image analysis, Image annotation, Visualisation, Data handling Imaging, Software engineering, Literature and language To update https://github.com/bmcv Imaging 2d_auto_threshold imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_auto_threshold/ 0.0.5-2 scikit-image (0/1) (1/1) (1/1) False -2d_feature_extraction 13760.0 19.0 ip_2d_feature_extraction 2D feature extraction scikit-image scikit-image scikit-image Scikit-image contains image processing algorithms for SciPy, including IO, morphology, filtering, warping, color manipulation, object detection, etc. Image analysis, Image annotation, Visualisation, Data handling Imaging, Software engineering, Literature and language To update https://github.com/bmcv Imaging 2d_feature_extraction imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_feature_extraction/ 0.1.1-2 pandas (0/1) (1/1) (1/1) False -2d_filter_segmentation_by_features 6834.0 18.0 ip_2d_filter_segmentation_by_features filter segmentation by rules galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging 2d_filter_segmentation_by_features imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_filter_segmentation_by_features/ 0.0.1-2 scikit-image (0/1) (1/1) (1/1) False -2d_histogram_equalization 656.0 39.0 ip_histogram_equalization 2d histogram equalization galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging 2d_histogram_equalization imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_histogram_equalization/ 0.0.1-2 scikit-image (0/1) (1/1) (1/1) False -2d_simple_filter 6156.0 35.0 ip_filter_standard 2d simple filter scikit-image scikit-image scikit-image Scikit-image contains image processing algorithms for SciPy, including IO, morphology, filtering, warping, color manipulation, object detection, etc. Image analysis, Image annotation, Visualisation, Data handling Imaging, Software engineering, Literature and language To update https://github.com/bmcv Imaging 2d_simple_filter imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_simple_filter/ 0.0.3-3 scikit-image (0/1) (1/1) (1/1) False -3d_tensor_feature_dimension_reduction ip_3d_tensor_feature_dimension_reduction Dimensionality reduction for features (channels) of 3D tensor data using UMAP To update https://github.com/BMCV/galaxy-image-analysis Imaging 3d_tensor_feature_dimension_reduction imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/3d_tensor_feature_dimension_reduction/ 0.0.1 numpy (0/1) (0/1) (0/1) False -anisotropic_diffusion 40.0 ip_anisotropic_diffusion Anisotropic image diffusion To update https://github.com/bmcv Imaging anisotropic_diffusion imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/anisotropic-diffusion/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False -bfconvert 1523.0 38.0 ip_convertimage Convert image python-bioformats To update https://github.com/bmcv Imaging, Convert Formats bfconvert imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/bfconvert/ 6.7.0+galaxy2 bftools 6.7.0 (0/1) (1/1) (1/1) False -binary2labelimage 1273.0 34.0 ip_binary_to_labelimage Binary 2 label image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging binary2labelimage imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/binary2labelimage/ 0.5 scikit-image (0/1) (1/1) (1/1) False -binaryimage2points 29.0 ip_binaryimage_to_points Binary Image to Points galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging binaryimage2points imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/binaryimage2points/ 0.1-2 numpy (0/1) (0/1) (1/1) False -bioformats2raw 9.0 bf2raw Convert image to OME-Zarr To update https://github.com/Euro-BioImaging Imaging, Convert Formats bioformats2raw imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/bioformats2raw 0.7.0 (0/1) (0/1) (1/1) False -color-deconvolution ip_color_deconvolution Color-deconvolution methods galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging color_deconvolution imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/color-deconvolution/ 0.8-2 scikit-image (0/1) (0/1) (1/1) False -concat_channels 78.0 3.0 ip_concat_channels Concatenate images galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging concat_channels imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/concat_channels/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False -coordinates_of_roi 16546.0 8.0 ip_coordinates_of_roi Coordinates of ROI galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging coordinates_of_roi imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/coordinates_of_roi/ 0.0.4-2 scikit-image (0/1) (0/1) (1/1) False -count_objects 272.0 25.0 ip_count_objects Count Objects galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging count_objects imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/count_objects/ 0.0.5-2 scikit-image (0/1) (1/1) (1/1) False -curve_fitting 12.0 1.0 ip_curve_fitting Polynomial curve fitting to data points galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/BMCV/galaxy-image-analysis Imaging curve_fitting imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/curve_fitting/ 0.0.3-2 numpy (0/1) (0/1) (1/1) False -detection_viz 46.0 2.0 ip_detection_viz Detection Visualization galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging detection_viz imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/detection_viz/ 0.3-2 scikit-image (0/1) (0/1) (1/1) False -image_info 621.0 41.0 ip_imageinfo Extracts image metadata python-bioformats To update https://github.com/bmcv Imaging image_info imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/image_info/ 5.7.1 bftools 6.7.0 (0/1) (1/1) (1/1) False -image_registration_affine 12.0 2.0 ip_image_registration Intensity-based Image Registration galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging image_registration_affine imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/image_registration_affine/ 0.0.3-2 scikit-image (0/1) (0/1) (1/1) False -imagecoordinates_flipaxis 21825.0 7.0 imagecoordinates_flipaxis Flip coordinate axes galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging imagecoordinates_flipaxis imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/imagecoordinates_flipaxis/ 0.1-2 pandas (0/1) (0/1) (1/1) False -labelimage2points 36.0 ip_labelimage_to_points Label Image to Points galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging labelimage2points imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/labelimage2points/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False -landmark_registration 857.0 9.0 ip_landmark_registration Landmark Registration galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging landmark_registration imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/landmark_registration/ 0.1.0-2 scikit-image (1/1) (0/1) (1/1) False -mahotas-features ip_mahotas_features Compute image features using mahotas. mahotas-feature-computation To update https://github.com/luispedro/mahotas Imaging mahotas_features imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/mahotas-features/ 0.7-2 mahotas (0/1) (0/1) (1/1) False -mergeneighboursinlabelimage 25.0 ip_merge_neighbours_in_label Merge Neighbours in Label Image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging mergeneighboursinlabelimage imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/\mergeneighboursinlabelimage 0.3-2 scikit-image (0/1) (0/1) (1/1) False -overlay_images 60.0 21.0 ip_overlay_images Overlay two images galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/BMCV/galaxy-image-analysis Imaging overlay_images imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/overlay_images/ 0.0.4 scikit-image (0/1) (0/1) (1/1) False -permutate_axis 42.0 ip_permutate_axis Permutates axes galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging permutate_axis imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/permutate_axis/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False -points2binaryimage 41.0 2.0 ip_points_to_binaryimage Points to Binary Image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging points2binaryimage imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/points2binaryimage/ 0.2-1 scikit-image (0/1) (0/1) (1/1) False -points2labelimage 66.0 ip_points_to_label Points to label image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging points2labelimage imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/points2labelimage/ 0.3-2 numpy (0/1) (0/1) (1/1) False -points_association_nn 29.0 2.0 ip_points_association_nn Association of points in consecutive frames galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/BMCV/galaxy-image-analysis Imaging points_association_nn imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/points_association_nn/ 0.0.3-2 numpy (0/1) (0/1) (1/1) False -projective_transformation 44.0 1.0 ip_projective_transformation Projective transformation galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging projective_transformation imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/projective_transformation/ 0.1.2-2 scikit-image (0/1) (0/1) (1/1) False -projective_transformation_points 21208.0 9.0 ip_projective_transformation_points Projective transformation of ROIs defined by pixel (point) coordinates galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging projective_transformation_points imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/projective_transformation_points/ 0.1.1-2 scikit-image (0/1) (0/1) (1/1) False -rfove 7.0 rfove Perform segmentation region-based fitting of overlapping ellipses rfove RFOVE RFOVE (Region-based Fitting of Overlapping Ellipses and its Application to Cells Segmentation) is a MATLAB script for performing image segmentation on cells. Image analysis Cell biology, Biomedical science, Imaging To update https://sites.google.com/site/costaspanagiotakis/research/cs Imaging rfove imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/rfove/ 2023.11.12 (0/1) (0/1) (1/1) False -scale_image 615.0 9.0 ip_scale_image Scale image scikit-image scikit-image scikit-image Scikit-image contains image processing algorithms for SciPy, including IO, morphology, filtering, warping, color manipulation, object detection, etc. Image analysis, Image annotation, Visualisation, Data handling Imaging, Software engineering, Literature and language To update https://github.com/bmcv Imaging scale_image imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/scale_image/ 0.4-2 pillow (0/1) (0/1) (1/1) False -segmetrics 3.0 2.0 ip_segmetrics Image segmentation and object detection performance measures segmetrics segmetrics SegMetrics Image segmentation and object detection performance measures Image analysis To update https://github.com/bmcv Imaging segmetrics imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/segmetrics/ 1.4 segmetrics 1.4.1 (0/1) (0/1) (1/1) False -slice_image 102.0 ip_slice_image Slice image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging slice_image imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/slice_image/ 0.3-2 scikit-image (0/1) (0/1) (1/1) False -split_labelmap 42.0 ip_split_labelmap Split Labelmaps galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging split_labelmap imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/split_labelmaps/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False -spot_detection_2d 16.0 3.0 ip_spot_detection_2d Spot detection in 2D image sequence galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/BMCV/galaxy-image-analysis Imaging spot_detection_2d imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/spot_detection_2d/ 0.0.3-2 imageio (0/1) (0/1) (1/1) False -superdsm 16.0 2.0 ip_superdsm Globally optimal segmentation method based on superadditivity and deformable shape models for cell nuclei in fluorescence microscopy images superdsm superdsm SuperDSM SuperDSM is a globally optimal segmentation method based on superadditivity and deformable shape models for cell nuclei in fluorescence microscopy images and beyond. Image analysis Up-to-date https://github.com/bmcv Imaging superdsm imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/superdsm/ 0.2.0 superdsm 0.2.0 (0/1) (0/1) (1/1) False -visceral-evaluatesegmentation ip_visceral_evaluatesegmentation Visceral Project - Evaluate Segmentation Tool evaluatesegmentation-tool To update https://github.com/bmcv Imaging visceral_evaluatesegmentation imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/visceral-evaluatesegmentation 0.5-2 visceral-evaluatesegmentation 2015.07.03 (0/1) (0/1) (1/1) False -wsi_extract_top_view 38.0 ip_wsi_extract_top_view WSI Extract Top View To update https://github.com/bmcv Imaging wsi_extract_top_view imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/wsi_extract_top_view/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False -cellpose cellpose Cellpose is an anatomical segmentation algorithm To update https://github.com/MouseLand/cellpose Imaging cellpose bgruening https://github.com/bgruening/galaxytools/tree/master/tools/cellpose 3.0.1 (0/1) (0/1) (1/1) False -cellprofiler cp_cellprofiler, cp_color_to_gray, cp_convert_objects_to_image, cp_display_data_on_image, cp_enhance_or_suppress_features, cp_export_to_spreadsheet, cp_gray_to_color, cp_identify_primary_objects, cp_image_math, cp_mask_image, cp_measure_granularity, cp_measure_image_area_occupied, cp_measure_image_intensity, cp_measure_image_quality, cp_measure_object_intensity, cp_measure_object_size_shape, cp_measure_texture, cp_overlay_outlines, cp_relate_objects, cp_save_images, cp_common, cp_tile, cp_track_objects cellProfiler wrapper CellProfiler cellprofiler CellProfiler Tool for quantifying data from biological images, particularly in high-throughput experiments. Quantification, Image analysis, Parsing Imaging, Microarray experiment, Genotype and phenotype To update Imaging cellprofiler bgruening https://github.com/bgruening/galaxytools/tree/master/tools (0/23) (23/23) (23/23) False -cellprofiler_v4 cp_cellprofiler4 cellProfiler4 wrapper To update Imaging cellprofiler4 bgruening https://github.com/bgruening/galaxytools/tree/master/tools 4.2.6 (0/1) (0/1) (1/1) False -bia-ftplinks bia_download Tool to query ftp links for study from bioimage archive To update Imaging bia_download bgruening https://github.com/bgruening/galaxytools/tree/master/tools 0.1.0 wget (0/1) (0/1) (1/1) False -graphicsmagick graphicsmagick_image_compare, graphicsmagick_image_convert, graphicsmagick_image_montage Contains tools based on GraphicsMagick To update http://www.graphicsmagick.org Imaging graphicsmagick bgruening https://github.com/bgruening/galaxytools/new/gm/tools/image_processing/image_processing/ 1.3.42 graphicsmagick 1.3.26 (1/3) (0/3) (3/3) False -imagej2 imagej2_adjust_threshold_binary, imagej2_analyze_particles_binary, imagej2_analyze_skeleton, imagej2_binary_to_edm, imagej2_bunwarpj_adapt_transform, imagej2_bunwarpj_align, imagej2_bunwarpj_compare_elastic, imagej2_bunwarpj_compare_elastic_raw, imagej2_bunwarpj_compare_raw, imagej2_bunwarpj_compose_elastic, imagej2_bunwarpj_compose_raw, imagej2_bunwarpj_compose_raw_elastic, imagej2_bunwarpj_convert_to_raw, imagej2_bunwarpj_elastic_transform, imagej2_bunwarpj_raw_transform, imagej2_create_image, imagej2_enhance_contrast, imagej2_find_edges, imagej2_find_maxima, imagej2_make_binary, imagej2_math, imagej2_noise, imagej2_shadows, imagej2_sharpen, imagej2_skeletonize3d, imagej2_smooth, imagej2_watershed_binary ImageJ2 is a new version of ImageJ for the next generation of multidimensionalimage data, with a focus on scientific imaging. imagej imagej2 ImageJ2 It is a public domain Java image processing program, which was designed with an open architecture. Custom acquisition, analysis and processing plugins can be developed using ImageJ’s built-in editor and a Java compiler. User-written plugins make it possible to solve many image processing and analysis problems, from three-dimensional live-cell imaging, to radiological image processing, multiple imaging system data comparisons to automated hematology systems. Image analysis, Image annotation, Visualisation Imaging To update http://fiji.sc Imaging imagej2 imgteam https://github.com/bgruening/galaxytools/tree/master/tools/image_processing/imagej2 (0/27) (0/27) (27/27) False -woundhealing woundhealing_scratch_assay Tool to automate quantification of wound healing in high-throughput microscopy scratch assays Up-to-date https://git.embl.de/grp-cba/wound-healing-htm-screen Imaging Wound healing scratch assay image analysis bgruening https://github.com/bgruening/galaxytools/tree/master/tools 1.6.1 fiji-morpholibj 1.6.1 (0/1) (0/1) (1/1) False -spyboat 67.0 1.0 spyboat Wavelet analysis for 3d-image stacks To update http://github.com/tensionhead/spyboat Imaging, Graphics spyboat iuc https://github.com/galaxyproject/tools-iuc/tree/master/packages/spyboat 0.1.2 spyboat (0/1) (0/1) (1/1) False -qupath_roi_splitter 59.0 5.0 qupath_roi_splitter Split ROI coordinates of QuPath TMA annotation by cell type To update https://github.com/npinter/ROIsplitter Imaging qupath_roi_splitter galaxyp hhttps://github.com/npinter/ROIsplitter 0.1.0+galaxy1 geojson (0/1) (0/1) (1/1) False -hyperstack_to_bleach_corrected_movie hyperstack_to_bleach_corrected_movie Generate blach corrected movie from hyperstack To update Imaging hyperstack_to_bleach_corrected_movie lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/hyperstack_to_bleach_corrected_movie 20230328 Fiji 20231211 (0/1) (0/1) (0/1) False -incucyte_stack_and_upload_omero incucyte_stack_and_upload_omero Combine images to stack and upload to the omero server To update Imaging incucyte_stack_and_upload_omero lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/incucyte_stack_and_upload_omero 20231221 Fiji 20231211 (0/1) (0/1) (0/1) False -measure_gastruloids measureGastruloids Get the ROI coordinates around the gastruloids as well as measurements like Area, elongation index To update Imaging measure_gastruloids lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/measure_gastruloids 20221216 fiji 20231211 (0/1) (0/1) (0/1) False -omero_clean_rois_tables omero_clean_rois_tables Remove all ROIs and all tables on OMERO associated to an omero object and recursively up and down To update Imaging omero_clean_rois_tables lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/omero_clean_rois_tables 20230623 fiji 20231211 (0/1) (0/1) (0/1) False -omero_get_children_ids omero_get_children_ids Get omero id of children of an omero object id To update Imaging omero_get_children_ids lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/omero_get_children_ids 0.1.0 omero-py 5.11.1 (0/1) (0/1) (0/1) False -omero_hyperstack_to_fluo_measurements_on_gastruloid omero_hyperstack_to_fluo_measurements_on_gastruloid Analyse Hyperstack on OMERO server to measure fluorescence levels To update Imaging omero_hyperstack_to_fluo_measurements_on_gastruloid lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/omero_hyperstack_to_fluo_measurements_on_gastruloid 20230809 fiji 20231211 (0/1) (0/1) (0/1) False -omero_hyperstack_to_gastruloid_measurements omero_hyperstack_to_gastruloid_measurements Analyse Hyperstack on OMERO server to segment gastruloid and compute measurements To update Imaging omero_hyperstack_to_gastruloid_measurements lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/omero_hyperstack_to_gastruloid_measurements 20240214 fiji 20231211 (0/1) (0/1) (0/1) False -upload_roi_and_measures_to_omero uploadROIandMeasuresToOMERO Upload the ROI coordinates and the measurements to the omero server To update Imaging upload_roi_and_measures_to_omero lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/upload_roi_and_measures_to_omero 0.0.5 omero-py 5.11.1 (0/1) (0/1) (0/1) False +Galaxy wrapper id Total tool usage (usegalaxy.eu) No. of tool users (2022-2023) (usegalaxy.eu) Galaxy tool ids Description bio.tool id bio.tool name bio.tool description EDAM operation EDAM topic Status Source ToolShed categories ToolShed id Galaxy wrapper owner Galaxy wrapper source Galaxy wrapper version Conda id Conda version https://usegalaxy.org https://usegalaxy.org.au https://usegalaxy.eu Reviewed To keep +2d_auto_threshold 6541.0 39.0 ip_threshold Automatic thresholding scikit-image scikit-image Scikit-image contains image processing algorithms for SciPy, including IO, morphology, filtering, warping, color manipulation, object detection, etc. Image analysis, Image annotation, Visualisation, Data handling Imaging, Software engineering, Literature and language To update https://github.com/bmcv Imaging 2d_auto_threshold imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_auto_threshold/ 0.0.5-2 scikit-image (0/1) (1/1) (1/1) False +2d_feature_extraction 13760.0 19.0 ip_2d_feature_extraction 2D feature extraction scikit-image scikit-image Scikit-image contains image processing algorithms for SciPy, including IO, morphology, filtering, warping, color manipulation, object detection, etc. Image analysis, Image annotation, Visualisation, Data handling Imaging, Software engineering, Literature and language To update https://github.com/bmcv Imaging 2d_feature_extraction imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_feature_extraction/ 0.1.1-2 pandas (0/1) (1/1) (1/1) False +2d_filter_segmentation_by_features 6834.0 18.0 ip_2d_filter_segmentation_by_features filter segmentation by rules galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging 2d_filter_segmentation_by_features imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_filter_segmentation_by_features/ 0.0.1-2 scikit-image (0/1) (1/1) (1/1) False +2d_histogram_equalization 656.0 39.0 ip_histogram_equalization 2d histogram equalization galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging 2d_histogram_equalization imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_histogram_equalization/ 0.0.1-2 scikit-image (0/1) (1/1) (1/1) False +2d_simple_filter 6156.0 35.0 ip_filter_standard 2d simple filter scikit-image scikit-image Scikit-image contains image processing algorithms for SciPy, including IO, morphology, filtering, warping, color manipulation, object detection, etc. Image analysis, Image annotation, Visualisation, Data handling Imaging, Software engineering, Literature and language To update https://github.com/bmcv Imaging 2d_simple_filter imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/2d_simple_filter/ 0.0.3-3 scikit-image (0/1) (1/1) (1/1) False +3d_tensor_feature_dimension_reduction ip_3d_tensor_feature_dimension_reduction Dimensionality reduction for features (channels) of 3D tensor data using UMAP To update https://github.com/BMCV/galaxy-image-analysis Imaging 3d_tensor_feature_dimension_reduction imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/3d_tensor_feature_dimension_reduction/ 0.0.1 numpy (0/1) (0/1) (0/1) False +anisotropic_diffusion 40.0 ip_anisotropic_diffusion Anisotropic image diffusion To update https://github.com/bmcv Imaging anisotropic_diffusion imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/anisotropic-diffusion/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False +bfconvert 1523.0 38.0 ip_convertimage Convert image To update https://github.com/bmcv Imaging, Convert Formats bfconvert imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/bfconvert/ 6.7.0+galaxy2 bftools 6.7.0 (0/1) (1/1) (1/1) False +binary2labelimage 1273.0 34.0 ip_binary_to_labelimage Binary 2 label image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging binary2labelimage imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/binary2labelimage/ 0.5 scikit-image (0/1) (1/1) (1/1) False +binaryimage2points 29.0 ip_binaryimage_to_points Binary Image to Points galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging binaryimage2points imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/binaryimage2points/ 0.1-2 numpy (0/1) (0/1) (1/1) False +bioformats2raw 9.0 bf2raw Convert image to OME-Zarr To update https://github.com/Euro-BioImaging Imaging, Convert Formats bioformats2raw imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/bioformats2raw 0.7.0 (0/1) (0/1) (1/1) False +color-deconvolution ip_color_deconvolution Color-deconvolution methods galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging color_deconvolution imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/color-deconvolution/ 0.8-2 scikit-image (0/1) (0/1) (1/1) False +concat_channels 78.0 3.0 ip_concat_channels Concatenate images galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging concat_channels imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/concat_channels/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False +coordinates_of_roi 16546.0 8.0 ip_coordinates_of_roi Coordinates of ROI galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging coordinates_of_roi imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/coordinates_of_roi/ 0.0.4-2 scikit-image (0/1) (0/1) (1/1) False +count_objects 272.0 25.0 ip_count_objects Count Objects galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging count_objects imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/count_objects/ 0.0.5-2 scikit-image (0/1) (1/1) (1/1) False +curve_fitting 12.0 1.0 ip_curve_fitting Polynomial curve fitting to data points galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/BMCV/galaxy-image-analysis Imaging curve_fitting imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/curve_fitting/ 0.0.3-2 numpy (0/1) (0/1) (1/1) False +detection_viz 46.0 2.0 ip_detection_viz Detection Visualization galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging detection_viz imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/detection_viz/ 0.3-2 scikit-image (0/1) (0/1) (1/1) False +image_info 621.0 41.0 ip_imageinfo Extracts image metadata To update https://github.com/bmcv Imaging image_info imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/image_info/ 5.7.1 bftools 6.7.0 (0/1) (1/1) (1/1) False +image_registration_affine 12.0 2.0 ip_image_registration Intensity-based Image Registration galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging image_registration_affine imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/image_registration_affine/ 0.0.3-2 scikit-image (0/1) (0/1) (1/1) False +imagecoordinates_flipaxis 21825.0 7.0 imagecoordinates_flipaxis Flip coordinate axes galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging imagecoordinates_flipaxis imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/imagecoordinates_flipaxis/ 0.1-2 pandas (0/1) (0/1) (1/1) False +labelimage2points 36.0 ip_labelimage_to_points Label Image to Points galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging labelimage2points imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/labelimage2points/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False +landmark_registration 857.0 9.0 ip_landmark_registration Landmark Registration galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging landmark_registration imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/landmark_registration/ 0.1.0-2 scikit-image (1/1) (0/1) (1/1) False +mahotas-features ip_mahotas_features Compute image features using mahotas. To update https://github.com/luispedro/mahotas Imaging mahotas_features imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/mahotas-features/ 0.7-2 mahotas (0/1) (0/1) (1/1) False +mergeneighboursinlabelimage 25.0 ip_merge_neighbours_in_label Merge Neighbours in Label Image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging mergeneighboursinlabelimage imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/\mergeneighboursinlabelimage 0.3-2 scikit-image (0/1) (0/1) (1/1) False +overlay_images 60.0 21.0 ip_overlay_images Overlay two images galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/BMCV/galaxy-image-analysis Imaging overlay_images imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/overlay_images/ 0.0.4 scikit-image (0/1) (0/1) (1/1) False +permutate_axis 42.0 ip_permutate_axis Permutates axes galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging permutate_axis imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/permutate_axis/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False +points2binaryimage 41.0 2.0 ip_points_to_binaryimage Points to Binary Image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging points2binaryimage imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/points2binaryimage/ 0.2-1 scikit-image (0/1) (0/1) (1/1) False +points2labelimage 66.0 ip_points_to_label Points to label image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging points2labelimage imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/points2labelimage/ 0.3-2 numpy (0/1) (0/1) (1/1) False +points_association_nn 29.0 2.0 ip_points_association_nn Association of points in consecutive frames galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/BMCV/galaxy-image-analysis Imaging points_association_nn imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/points_association_nn/ 0.0.3-2 numpy (0/1) (0/1) (1/1) False +projective_transformation 44.0 1.0 ip_projective_transformation Projective transformation galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging projective_transformation imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/projective_transformation/ 0.1.2-2 scikit-image (0/1) (0/1) (1/1) False +projective_transformation_points 21208.0 9.0 ip_projective_transformation_points Projective transformation of ROIs defined by pixel (point) coordinates galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging projective_transformation_points imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/projective_transformation_points/ 0.1.1-2 scikit-image (0/1) (0/1) (1/1) False +rfove 7.0 rfove Perform segmentation region-based fitting of overlapping ellipses rfove RFOVE RFOVE (Region-based Fitting of Overlapping Ellipses and its Application to Cells Segmentation) is a MATLAB script for performing image segmentation on cells. Image analysis Cell biology, Biomedical science, Imaging To update https://sites.google.com/site/costaspanagiotakis/research/cs Imaging rfove imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/rfove/ 2023.11.12 (0/1) (0/1) (1/1) False +scale_image 615.0 9.0 ip_scale_image Scale image scikit-image scikit-image Scikit-image contains image processing algorithms for SciPy, including IO, morphology, filtering, warping, color manipulation, object detection, etc. Image analysis, Image annotation, Visualisation, Data handling Imaging, Software engineering, Literature and language To update https://github.com/bmcv Imaging scale_image imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/scale_image/ 0.4-2 pillow (0/1) (0/1) (1/1) False +segmetrics 3.0 2.0 ip_segmetrics Image segmentation and object detection performance measures segmetrics SegMetrics Image segmentation and object detection performance measures Image analysis To update https://github.com/bmcv Imaging segmetrics imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/segmetrics/ 1.4 segmetrics 1.4.1 (0/1) (0/1) (1/1) False +slice_image 102.0 ip_slice_image Slice image galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging slice_image imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/slice_image/ 0.3-2 scikit-image (0/1) (0/1) (1/1) False +split_labelmap 42.0 ip_split_labelmap Split Labelmaps galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/bmcv Imaging split_labelmap imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/split_labelmaps/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False +spot_detection_2d 16.0 3.0 ip_spot_detection_2d Spot detection in 2D image sequence galaxy_image_analysis Galaxy Image Analysis Developed within the Biomedical Computer Vision (BMCV) Group Heidelberg. Image analysis Imaging, Bioinformatics To update https://github.com/BMCV/galaxy-image-analysis Imaging spot_detection_2d imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/spot_detection_2d/ 0.0.3-2 imageio (0/1) (0/1) (1/1) False +superdsm 16.0 2.0 ip_superdsm Globally optimal segmentation method based on superadditivity and deformable shape models for cell nuclei in fluorescence microscopy images superdsm SuperDSM SuperDSM is a globally optimal segmentation method based on superadditivity and deformable shape models for cell nuclei in fluorescence microscopy images and beyond. Image analysis Up-to-date https://github.com/bmcv Imaging superdsm imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/superdsm/ 0.2.0 superdsm 0.2.0 (0/1) (0/1) (1/1) False +visceral-evaluatesegmentation ip_visceral_evaluatesegmentation Visceral Project - Evaluate Segmentation Tool To update https://github.com/bmcv Imaging visceral_evaluatesegmentation imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/visceral-evaluatesegmentation 0.5-2 visceral-evaluatesegmentation 2015.07.03 (0/1) (0/1) (1/1) False +wsi_extract_top_view 38.0 ip_wsi_extract_top_view WSI Extract Top View To update https://github.com/bmcv Imaging wsi_extract_top_view imgteam https://github.com/BMCV/galaxy-image-analysis/tree/master/tools/wsi_extract_top_view/ 0.2-2 scikit-image (0/1) (0/1) (1/1) False +cellprofiler cp_cellprofiler, cp_color_to_gray, cp_convert_objects_to_image, cp_display_data_on_image, cp_enhance_or_suppress_features, cp_export_to_spreadsheet, cp_gray_to_color, cp_identify_primary_objects, cp_image_math, cp_mask_image, cp_measure_granularity, cp_measure_image_area_occupied, cp_measure_image_intensity, cp_measure_image_quality, cp_measure_object_intensity, cp_measure_object_size_shape, cp_measure_texture, cp_overlay_outlines, cp_relate_objects, cp_save_images, cp_common, cp_tile, cp_track_objects cellProfiler wrapper CellProfiler CellProfiler Tool for quantifying data from biological images, particularly in high-throughput experiments. Quantification, Image analysis, Parsing Imaging, Microarray experiment, Genotype and phenotype To update Imaging cellprofiler bgruening https://github.com/bgruening/galaxytools/tree/master/tools (0/23) (23/23) (23/23) False +cellprofiler_v4 cp_cellprofiler4 cellProfiler4 wrapper To update Imaging cellprofiler4 bgruening https://github.com/bgruening/galaxytools/tree/master/tools 4.2.6 (0/1) (0/1) (1/1) False +bia-ftplinks bia_download Tool to query ftp links for study from bioimage archive To update Imaging bia_download bgruening https://github.com/bgruening/galaxytools/tree/master/tools 0.1.0 wget (0/1) (0/1) (1/1) False +graphicsmagick graphicsmagick_image_compare, graphicsmagick_image_convert, graphicsmagick_image_montage Contains tools based on GraphicsMagick To update http://www.graphicsmagick.org Imaging graphicsmagick bgruening https://github.com/bgruening/galaxytools/new/gm/tools/image_processing/image_processing/ 1.3.42 graphicsmagick 1.3.26 (1/3) (0/3) (3/3) False +imagej2 imagej2_adjust_threshold_binary, imagej2_analyze_particles_binary, imagej2_analyze_skeleton, imagej2_binary_to_edm, imagej2_bunwarpj_adapt_transform, imagej2_bunwarpj_align, imagej2_bunwarpj_compare_elastic, imagej2_bunwarpj_compare_elastic_raw, imagej2_bunwarpj_compare_raw, imagej2_bunwarpj_compose_elastic, imagej2_bunwarpj_compose_raw, imagej2_bunwarpj_compose_raw_elastic, imagej2_bunwarpj_convert_to_raw, imagej2_bunwarpj_elastic_transform, imagej2_bunwarpj_raw_transform, imagej2_create_image, imagej2_enhance_contrast, imagej2_find_edges, imagej2_find_maxima, imagej2_make_binary, imagej2_math, imagej2_noise, imagej2_shadows, imagej2_sharpen, imagej2_skeletonize3d, imagej2_smooth, imagej2_watershed_binary ImageJ2 is a new version of ImageJ for the next generation of multidimensionalimage data, with a focus on scientific imaging. imagej ImageJ2 It is a public domain Java image processing program, which was designed with an open architecture. Custom acquisition, analysis and processing plugins can be developed using ImageJ’s built-in editor and a Java compiler. User-written plugins make it possible to solve many image processing and analysis problems, from three-dimensional live-cell imaging, to radiological image processing, multiple imaging system data comparisons to automated hematology systems. Image analysis, Image annotation, Visualisation Imaging To update http://fiji.sc Imaging imagej2 imgteam https://github.com/bgruening/galaxytools/tree/master/tools/image_processing/imagej2 (0/27) (0/27) (27/27) False +spyboat 67.0 1.0 spyboat Wavelet analysis for 3d-image stacks To update http://github.com/tensionhead/spyboat Imaging, Graphics spyboat iuc https://github.com/galaxyproject/tools-iuc/tree/master/packages/spyboat 0.1.2 spyboat (0/1) (0/1) (1/1) False +qupath_roi_splitter 59.0 5.0 qupath_roi_splitter Split ROI coordinates of QuPath TMA annotation by cell type To update https://github.com/npinter/ROIsplitter Imaging qupath_roi_splitter galaxyp hhttps://github.com/npinter/ROIsplitter 0.1.0+galaxy1 geojson (0/1) (0/1) (1/1) False +hyperstack_to_bleach_corrected_movie hyperstack_to_bleach_corrected_movie Generate blach corrected movie from hyperstack To update Imaging hyperstack_to_bleach_corrected_movie lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/hyperstack_to_bleach_corrected_movie 20230328 Fiji 20231211 (0/1) (0/1) (0/1) False +incucyte_stack_and_upload_omero incucyte_stack_and_upload_omero Combine images to stack and upload to the omero server To update Imaging incucyte_stack_and_upload_omero lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/incucyte_stack_and_upload_omero 20231221 Fiji 20231211 (0/1) (0/1) (0/1) False +measure_gastruloids measureGastruloids Get the ROI coordinates around the gastruloids as well as measurements like Area, elongation index To update Imaging measure_gastruloids lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/measure_gastruloids 20221216 fiji 20231211 (0/1) (0/1) (0/1) False +omero_clean_rois_tables omero_clean_rois_tables Remove all ROIs and all tables on OMERO associated to an omero object and recursively up and down To update Imaging omero_clean_rois_tables lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/omero_clean_rois_tables 20230623 fiji 20231211 (0/1) (0/1) (0/1) False +omero_get_children_ids omero_get_children_ids Get omero id of children of an omero object id To update Imaging omero_get_children_ids lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/omero_get_children_ids 0.1.0 omero-py 5.11.1 (0/1) (0/1) (0/1) False +omero_hyperstack_to_fluo_measurements_on_gastruloid omero_hyperstack_to_fluo_measurements_on_gastruloid Analyse Hyperstack on OMERO server to measure fluorescence levels To update Imaging omero_hyperstack_to_fluo_measurements_on_gastruloid lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/omero_hyperstack_to_fluo_measurements_on_gastruloid 20230809 fiji 20231211 (0/1) (0/1) (0/1) False +omero_hyperstack_to_gastruloid_measurements omero_hyperstack_to_gastruloid_measurements Analyse Hyperstack on OMERO server to segment gastruloid and compute measurements To update Imaging omero_hyperstack_to_gastruloid_measurements lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/omero_hyperstack_to_gastruloid_measurements 20240214 fiji 20231211 (0/1) (0/1) (0/1) False +upload_roi_and_measures_to_omero uploadROIandMeasuresToOMERO Upload the ROI coordinates and the measurements to the omero server To update Imaging upload_roi_and_measures_to_omero lldelisle https://github.com/lldelisle/tools-lldelisle/tree/master/tools/upload_roi_and_measures_to_omero 0.0.5 omero-py 5.11.1 (0/1) (0/1) (0/1) False \ No newline at end of file diff --git a/results/microgalaxy/index.html b/results/microgalaxy/index.html index 1a1d4ce8..e9388ce3 100644 --- a/results/microgalaxy/index.html +++ b/results/microgalaxy/index.html @@ -763,7 +763,6 @@ Molecular interactions, pathways and networks, Gene and protein families Antismash allows the genome-wide identification, annotation and analysis of secondary metabolite biosynthesis gene clusters Rapid genome-wide identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genomes. It integrates and cross-links with a large number of in silico secondary metabolite analysis tools that have been published earlier. - To update https://antismash.secondarymetabolites.org Sequence Analysis @@ -1120,7 +1119,6 @@ Sequence sites, features and motifs Infernal ("INFERence of RNA ALignment") is for searching DNA sequence databases for RNA structure and sequence similarities. Infernal ("INFERence of RNA ALignment") is for searching DNA sequence databases for RNA structure and sequence similarities. It is an implementation of a special case of profile stochastic context-free grammars called covariance models (CMs). A CM is like a sequence profile, but it scores a combination of sequence consensus and RNA secondary structure consensus, so in many cases, it is more capable of identifying RNA homologs that conserve their secondary structure more than their primary sequence. - To update http://infernal.janelia.org/ RNA @@ -1246,7 +1244,6 @@ Search for transcription associated proteins (TAPs) - To update https://plantcode.cup.uni-freiburg.de/tapscan/ Proteomics @@ -1393,7 +1390,6 @@ Sequence assembly Assembly By Short Sequences - a de novo, parallel, paired-end sequence assembler De novo genome sequence assembler using short reads. - Up-to-date http://www.bcgsc.ca/platform/bioinfo/software/abyss Assembly @@ -1582,7 +1578,6 @@ Construct sequence similarity networks of BGCs and groups them into GCF - Up-to-date https://github.com/medema-group/BiG-SCAPE Metagenomics @@ -1708,7 +1703,6 @@ Metagenomics, Metagenomic sequencing, Taxonomy, Sequence assembly Contig Annotation Tool (CAT) Contig Annotation Tool (CAT) and Bin Annotation Tool (BAT) are pipelines for the taxonomic classification of long DNA sequences and metagenome assembled genomes (MAGs/bins) of both known and (highly) unknown microorganisms, as generated by contemporary metagenomics studies. The core algorithm of both programs involves gene calling, mapping of predicted ORFs against the nr protein database, and voting-based classification of the entire contig / MAG based on classification of the individual ORFs. - To update https://github.com/dutilh/CAT Metagenomics @@ -1855,7 +1849,6 @@ Compleasm: a faster and more accurate reimplementation of BUSCO - Up-to-date https://github.com/huangnengCSU/compleasm Sequence Analysis @@ -1897,7 +1890,6 @@ Bioinformatics CoverM genome and contig wrappers Read coverage calculator for metagenomics - Up-to-date https://github.com/wwood/CoverM Sequence Analysis @@ -1960,7 +1952,6 @@ Metagenomics DAS Tool for genome resolved metagenomics DAS Tool is an automated method that integrates the results of a flexible number of binning algorithms to calculate an optimized, non-redundant set of bins from a single assembly. - Up-to-date https://github.com/cmks/DAS_Tool Metagenomics @@ -2443,7 +2434,6 @@ Sequence analysis, Sequence sites, features and motifs, Gene and protein families HMMER is used for searching sequence databases for homologs of proteinsequences, and for making protein sequence alignments. It implementsmethods using probabilistic models called profile hidden Markov models(profile HMMs). This tool is used for searching sequence databases for homologs of protein sequences, and for making protein sequence alignments. It implements methods using probabilistic models called profile hidden Markov models. The new HMMER3 project, HMMER is now as fast as BLAST for protein search. - Up-to-date http://hmmer.org/ Sequence Analysis @@ -2527,7 +2517,6 @@ Mobile genetic elements, Sequence sites, features and motifs, Genomics, Molecular interactions, pathways and networks, Structural variation ICEscreen identifies Integrative Conjugative Elements (ICEs) and Integrative Mobilizable Elements (IMEs) in Bacillota genomes. A tool to detect Firmicute ICEs and IMEs, isolated or enclosed in composite structures. - To update https://icescreen.migale.inrae.fr/ Genome annotation @@ -3031,7 +3020,6 @@ Fast local alignment boundaries - Up-to-date https://github.com/galaxyproject/tools-iuc/tree/master/tools/mashmap Sequence Analysis @@ -3304,7 +3292,6 @@ Metagenomics, Phylogenomics MetaPhlAn for Metagenomic Phylogenetic Analysis Computational tool for profiling the composition of microbial communities from metagenomic shotgun sequencing data. - To update https://github.com/biobakery/MetaPhlAn Metagenomics @@ -3451,7 +3438,6 @@ Metabolomics, Molecular interactions, pathways and networks, Proteomics, Transcriptomics, Small molecules GSEA-based pathway enrichment analysis for multi-omics data A GSEA-based pathway enrichment analysis for multi-omics data.multiGSEA: a GSEA-based pathway enrichment analysis for multi-omics data, BMC Bioinformatics 21, 561 (2020).Combining GSEA-based pathway enrichment with multi omics data integration. - Up-to-date https://bioconductor.org/packages/devel/bioc/html/multiGSEA.html Transcriptomics, Proteomics, Statistics @@ -3463,7 +3449,7 @@ multiqc 1.11 - 1.21 + 1.20 multiqc To update multiqc @@ -3682,7 +3668,6 @@ Proteome quality assessment software - To update https://github.com/DessimozLab/OMArk Sequence Analysis @@ -4081,7 +4066,6 @@ Randomly subsample sequencing reads to a specified coverage Produces an unbiased subsample of your reads - Up-to-date https://github.com/mbhall88/rasusa Sequence Analysis @@ -4144,7 +4128,6 @@ Metagenomics, Microbial ecology, Metagenomic sequencing "With Recentrifuge, researchers can analyze results from taxonomic classifiers using interactive charts with emphasis on the confidence level of the classifications.In addition to contamination-subtracted samples.Recentrifuge provides shared and exclusive taxa per sample,thus enabling robust contamination removal and comparative analysis in environmental and clinical metagenomics." Robust comparative analysis and contamination removal for metagenomics. - Up-to-date https://github.com/khyox/recentrifuge Metagenomics @@ -4312,7 +4295,6 @@ Genomics, Sequence assembly, Sequencing, Probes and primers Tool for merging paired-end Illumina reads and trimming adapters. Strips adapters and optionally merges overlapping paired-end (or paired-end contamination in mate-pair libraries) illumina style reads. - Up-to-date https://github.com/jstjohn/SeqPrep Fastq Manipulation, Sequence Analysis @@ -4459,7 +4441,6 @@ Sequence assembly, Sequence sites, features and motifs, Genetic engineering SPAdes is an assembly toolkit containing various assembly pipelines. It implements the following 4 stages: assembly graph construction, k-bimer adjustment, construction of paired assembly graph and contig construction. biosyntheticSPAdes - biosynthetic gene cluster assembly with paired-end reads - Up-to-date https://github.com/ablab/spades Assembly, RNA, Metagenomics @@ -5026,7 +5007,6 @@ Retrieve environmental data from etopo, cmems and woa - To update https://github.com/jeremyfix/medenv Ecology, Data Source diff --git a/results/microgalaxy/tools.tsv b/results/microgalaxy/tools.tsv index de3772c4..634c911b 100644 --- a/results/microgalaxy/tools.tsv +++ b/results/microgalaxy/tools.tsv @@ -1,339 +1,339 @@ -Galaxy wrapper id Total tool usage (usegalaxy.eu) No. of tool users (2022-2023) (usegalaxy.eu) Galaxy tool ids Description bio.tool id biii bio.tool name bio.tool description EDAM operation EDAM topic Status Source ToolShed categories ToolShed id Galaxy wrapper owner Galaxy wrapper source Galaxy wrapper version Conda id Conda version https://usegalaxy.org https://usegalaxy.org.au https://usegalaxy.eu Reviewed To keep -braker 109.0 17.0 braker BRAKER is a pipeline for fully automated prediction of protein coding gene structures with GeneMark-ES/ET and AUGUSTUS in novel eukaryotic genomes . To update https://github.com/Gaius-Augustus/BRAKER Genome annotation braker genouest https://github.com/genouest/galaxy-tools/tree/master/tools/braker 2.1.6 (0/1) (0/1) (1/1) True False -braker3 567.0 10.0 braker3 BRAKER3 is a pipeline for fully automated prediction of protein coding gene structures with GeneMark-ES/ET and AUGUSTUS in novel eukaryotic genomes . To update https://github.com/Gaius-Augustus/BRAKER Genome annotation braker3 genouest https://github.com/genouest/galaxy-tools/tree/master/tools/braker 3.0.8 (0/1) (1/1) (1/1) True False -helixer 93.0 1.0 helixer Gene calling with Deep Neural Networks To update https://github.com/weberlab-hhu/Helixer Genome annotation helixer genouest https://github.com/genouest/galaxy-tools/tree/master/tools/helixer 0.3.2 (0/1) (0/1) (1/1) True False -logol logol_wrapper Logol is a pattern matching grammar language and a set of tools to search a pattern in a sequence Up-to-date http://logol.genouest.org/web/app.php/logol Sequence Analysis genouest https://github.com/genouest/galaxy-tools/tree/master/tools/logol 1.7.8 logol 1.7.8 (0/1) (0/1) (0/1) True False -peptimapper peptimapper_clustqualify, peptimapper_clust_to_gff, peptimapper_pep_match, peptimapper_pep_novo_tag Proteogenomics workflow for the expert annotation of eukaryotic genomes To update https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5431-9 Proteomics genouest 2.0 (0/4) (0/4) (0/4) True False -GAFA gafa Gene Align and Family Aggregator To update http://aequatus.tgac.ac.uk Visualization gafa earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/GAFA/ 0.3.1 (0/1) (0/1) (1/1) True False -TreeBest treebest_best TreeBeST best To update http://treesoft.sourceforge.net/treebest.shtml Phylogenetics treebest_best earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/TreeBest 1.9.2.post0 treebest 1.9.2.post1 (0/1) (0/1) (1/1) True True -blast_parser 296.0 27.0 blast_parser Convert 12- or 24-column BLAST output into 3-column hcluster_sg input To update https://github.com/TGAC/earlham-galaxytools/ Phylogenetics blast_parser earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/blast_parser 0.1.2 (0/1) (0/1) (1/1) True False -ete 1255.0 67.0 ete_gene_csv_finder, ete_genetree_splitter, ete_homology_classifier, ete_init_taxdb, ete_lineage_generator, ete3_mod, ete_species_tree_generator Analyse phylogenetic trees using the ETE Toolkit To update http://etetoolkit.org/ Phylogenetics ete earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/ete 3.1.2 ete3 3.1.1 (0/7) (0/7) (7/7) True True -gblocks gblocks Gblocks Up-to-date http://molevol.cmima.csic.es/castresana/Gblocks.html Sequence Analysis gblocks earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/gblocks 0.91b gblocks 0.91b (0/1) (1/1) (0/1) True False -hcluster_sg 238.0 13.0 hcluster_sg Hierarchically clustering on a sparse graph To update https://github.com/douglasgscofield/hcluster Phylogenetics hcluster_sg earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/hcluster_sg 0.5.1.1 hcluster_sg 0.5.1 (0/1) (0/1) (1/1) True False -hcluster_sg_parser 290.0 7.0 hcluster_sg_parser Converts hcluster_sg 3-column output into lists of ids To update https://github.com/TGAC/earlham-galaxytools/ Phylogenetics hcluster_sg_parser earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/hcluster_sg_parser 0.2.1 (0/1) (0/1) (1/1) True False -lotus2 936.0 114.0 lotus2 LotuS2 OTU processing pipeline lotus2 lotus2 LotuS2 is a lightweight and user-friendly pipeline that is fast, precise, and streamlined, using extensive pre- and post-ASV/OTU clustering steps to further increase data quality. High data usage rates and reliability enable high-throughput microbiome analysis in minutes. Sequence feature detection Metagenomics Up-to-date http://lotus2.earlham.ac.uk/ Metagenomics lotus2 earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/lotus2 2.32 lotus2 2.32 (0/1) (0/1) (1/1) True True -miranda 6076.0 41.0 miranda Finds potential target sites for miRNAs in genomic sequences To update http://www.microrna.org/ RNA miranda earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/miranda 3.3a+galaxy1 miranda 3.3a (0/1) (0/1) (1/1) True False -smart_domains smart_domains SMART domains To update http://smart.embl.de/ Sequence Analysis smart_domains earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/smart_domains 0.1.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False -t_coffee 8690.0 70.0 t_coffee T-Coffee To update http://www.tcoffee.org/ Sequence Analysis t_coffee earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/t_coffee 13.45.0.4846264 t-coffee 13.46.0.919e8c6b (0/1) (0/1) (1/1) True False -abacas abacas Order and Orientate Contigs To update https://github.com/phac-nml/abacas Assembly abacas nml https://github.com/phac-nml/abacas 1.1 mummer 3.23 (0/1) (0/1) (0/1) True True -assemblystats assemblystats Summarise an assembly (e.g. N50 metrics) To update https://github.com/phac-nml/galaxy_tools Assembly assemblystats nml https://github.com/phac-nml/galaxy_tools 1.1.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True True -bam2mappingstats bam2mappingstats Generates mapping stats from a bam file. To update https://github.com/phac-nml/galaxy_tools Assembly bam2mappingstats nml https://github.com/phac-nml/galaxy_tools 1.1.0 perl (0/1) (0/1) (0/1) True False -bamclipper bamclipper Soft-clip gene-specific primers from BAM alignment file based on genomic coordinates of primer pairs in BEDPE format. Up-to-date https://github.com/tommyau/bamclipper Sequence Analysis bamclipper nml https://github.com/tommyau/bamclipper 1.0.0 bamclipper 1.0.0 (0/1) (0/1) (0/1) True False -biohansel biohansel Heidelberg and Enteritidis SNP Elucidation To update https://github.com/phac-nml/biohansel Sequence Analysis biohansel nml https://github.com/phac-nml/biohansel 2.4.0 bio_hansel 2.6.1 (0/1) (0/1) (0/1) True True -bundle_collections bundle_collection Tool to bundle up list collection into a single zip to be download To update Sequence Analysis bundle_collections nml 1.3.0 perl-getopt-long 2.54 (0/1) (1/1) (0/1) True False -collapse_collection collapse_dataset Collection tool that collapses a list of files into a single datasset in order of appears in collection To update Sequence Analysis collapse_collections nml 5.1.0 gawk (1/1) (1/1) (1/1) True False -combineJSON combine_json JSON collection tool that takes multiple JSON data arrays and combines them into a single JSON array. To update Sequence Analysis combine_json nml 0.1 (0/1) (0/1) (0/1) True False -combine_assembly_stats combine_stats Combine multiple Assemblystats datasets into a single tabular report To update https://github.com/phac-nml/galaxy_tools Assembly combine_assemblystats nml https://github.com/phac-nml/galaxy_tools 1.0 perl-getopt-long 2.54 (0/1) (0/1) (0/1) True True -combine_tabular_collection combine Combine Tabular Collection into a single file To update Sequence Analysis combine_tabular_collection nml 0.1 (0/1) (0/1) (0/1) True False -cryptogenotyper 8518.0 16.0 CryptoGenotyper CryptoGenotyper is a standalone tool to *in-silico* determine species and subtype based on SSU rRNA and gp60 markers. Up-to-date https://github.com/phac-nml/CryptoGenotyper Sequence Analysis cryptogenotyper nml https://github.com/phac-nml/CryptoGenotyper 1.0 cryptogenotyper 1.0 (0/1) (0/1) (1/1) True True -ectyper 9907.0 53.0 ectyper EC-Typer - in silico serotyping of Escherichia coli species Up-to-date https://github.com/phac-nml/ecoli_serotyping Sequence Analysis ectyper nml https://github.com/phac-nml/ecoli_serotyping 1.0.0 ectyper 1.0.0 (0/1) (0/1) (1/1) True True -fasta2bed fasta2bed Convert multiple fasta file into tabular bed file format To update https://github.com/phac-nml/galaxy_tools Sequence Analysis fasta2bed nml https://github.com/phac-nml/galaxy_tools 1.0.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False -fasta_extract 10.0 fa-extract-sequence extract single fasta from multiple fasta file To update https://toolshed.g2.bx.psu.edu/view/nml/fasta_extract Sequence Analysis fasta_extract nml https://toolshed.g2.bx.psu.edu/view/nml/fasta_extract 1.1.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False -fastqc_stats FastQC_Summary Summary multiple FastQC into a single tabular line report To update https://github.com/phac-nml/galaxy_tools Sequence Analysis fastqc_stats nml https://github.com/phac-nml/galaxy_tools 1.2 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False -feht feht Automatically identify makers predictive of groups. To update https://github.com/phac-nml/galaxy_tools Sequence Analysis feht nml https://github.com/phac-nml/galaxy_tools 0.1.0 feht 1.1.0 (0/1) (0/1) (0/1) True False -filter_spades_repeats filter_spades_repeat Remove short and repeat contigs/scaffolds To update https://github.com/phac-nml/galaxy_tools/ Assembly filter_spades_repeats nml https://github.com/phac-nml/galaxy_tools/ 1.0.1 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True True -getmlst getmlst Download MLST datasets by species from pubmlst.org To update Sequence Analysis getmlst nml 0.1.4.1 srst2 0.2.0 (0/1) (0/1) (0/1) True True -hivtrace hivtrace An application that identifies potential transmission clusters within a supplied FASTA file with an option to find potential links against the Los Alamos HIV Sequence Database. To update Sequence Analysis hivtrace nml https://github.com/phac-nml/galaxy_tools/tree/tools/hivtrace 1.0.1 hivtrace 1.5.0 (0/1) (0/1) (0/1) True True -kaptive kaptive Kaptive reports information about capsular (K) loci found in genome assemblies. To update Sequence Analysis kaptive nml 0.3.0 kaptive 2.0.6 (0/1) (0/1) (0/1) True False -kat_filter kat_@EXECUTABLE@ Filtering kmers or reads from a database of kmers hashes To update Sequence Analysis kat_filter nml 2.3 kat 2.4.2 (0/1) (0/1) (0/1) True True -mauve_contig_mover mauve_contig_mover Order a draft genome relative to a related reference genome To update https://github.com/phac-nml/mauve_contig_mover Sequence Analysis mauve_contig_mover nml https://github.com/phac-nml/mauve_contig_mover 1.0.10 mauve 2.4.0.r4736 (0/1) (0/1) (0/1) True False -mob_suite 89021.0 322.0 mob_recon, mob_typer MOB-suite is a set of software tools for clustering, reconstruction and typing of plasmids from draft assemblies To update https://github.com/phac-nml/mob-suite Sequence Analysis mob_suite nml https://github.com/phac-nml/mob-suite 3.0.3 mob_suite 3.1.8 (0/2) (2/2) (2/2) True True -mrbayes mrbayes A program for the Bayesian estimation of phylogeny. To update Sequence Analysis mrbayes nml 1.0.2 mrbayes 3.2.7 (0/1) (0/1) (0/1) True True -mykrobe_parser mykrobe_parseR RScript to parse the results of mykrobe predictor. To update https://github.com/phac-nml/mykrobe-parser Sequence Analysis mykrobe_parser nml https://github.com/phac-nml/mykrobe-parser 0.1.4.1 r-base (0/1) (0/1) (0/1) True True -pangolin 7276.0 259.0 pangolin Phylogenetic Assignment of Named Global Outbreak LINeages To update https://github.com/hCoV-2019/pangolin Sequence Analysis pangolin nml https://github.com/hCoV-2019/pangolin 1.1.14 pangolin 4.3 (1/1) (1/1) (1/1) True False -patrist patrist Extract Patristic Distance From a Tree To update https://gist.github.com/ArtPoon/7330231e74201ded54b87142a1d6cd02 Phylogenetics patrist nml https://github.com/phac-nml/patrist 0.1.2 python (0/1) (0/1) (0/1) True False -plasmid_profiler_suite Plasmid Profiler suite defining all dependencies for Plasmid Profiler To update Sequence Analysis suite_plasmid_profiler nml (0/1) (0/1) (0/1) True False -plasmidspades plasmidspades Genome assembler for assemblying plasmid To update Assembly plasmidspades nml 1.1 spades 3.15.5 (0/1) (0/1) (0/1) True True -promer promer4_substitutions Aligns two sets of contigs and reports amino acid substitutions between them To update https://github.com/phac-nml/promer Assembly promer nml https://github.com/phac-nml/promer 1.2 python (0/1) (0/1) (0/1) True True -pseudogenome pseudogenome Create a pseudogenome from a multiple fasta file either with a JCVI linker or custom length and characters. To update https://github.com/phac-nml/galaxy_tools Sequence Analysis pseudogenome nml 1.0.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False -quasitools aacoverage, aavariants, callcodonvar, callntvar, complexity_bam, complexity_fasta, consensus, distance, dnds, drmutations, hydra, quality A collection of tools for analysing Viral Quasispecies Up-to-date https://github.com/phac-nml/quasitools Sequence Analysis quasitools nml https://github.com/phac-nml/quasitools 0.7.0 quasitools 0.7.0 (0/12) (12/12) (0/12) True False -refseq_masher refseq_masher_contains, refseq_masher_matches Find what genomes match or are contained within your sequence data using Mash_ and a Mash sketch database. Up-to-date https://github.com/phac-nml/refseq_masher Sequence Analysis refseq_masher nml https://github.com/phac-nml/refseq_masher 0.1.2 refseq_masher 0.1.2 (0/2) (0/2) (0/2) True False -seqtk_nml seqtk_nml_sample Tool to downsample fastq reads To update https://github.com/lh3/seqtk Sequence Analysis seqtk_nml nml https://github.com/phac-nml/snvphyl-galaxy 1.0.1 seqtk 1.4 (0/1) (0/1) (0/1) True False -sistr_cmd 2489.0 133.0 sistr_cmd SISTR in silico serotyping tool Up-to-date https://github.com/phac-nml/sistr_cmd Sequence Analysis sistr_cmd nml 1.1.1 sistr_cmd 1.1.1 (0/1) (1/1) (1/1) True True -smalt smalt SMALT aligns DNA sequencing reads with a reference genome. Up-to-date http://www.sanger.ac.uk/science/tools/smalt-0 Sequence Analysis smalt nml https://sourceforge.net/projects/smalt/ 0.7.6 smalt 0.7.6 (0/1) (0/1) (0/1) True True -spatyper spatyper Determines SPA type based on repeats in a submitted staphylococcal protein A fasta file. Up-to-date https://github.com/HCGB-IGTP/spaTyper Sequence Analysis spatyper nml https://github.com/phac-nml/galaxy_tools/tree/master/tools/spatyper 0.3.3 spatyper 0.3.3 (0/1) (0/1) (0/1) True False -spolpred spolpred A program for predicting the spoligotype from raw sequence reads To update Sequence Analysis spolpred nml 1.0.1 spolpred (0/1) (0/1) (0/1) True False -srst2 205.0 22.0 srst2 Short Read Sequence Typing for Bacterial Pathogens To update Sequence Analysis srst2 nml 0.3.7 srst2 0.2.0 (0/1) (0/1) (1/1) True True -staramr 12673.0 889.0 staramr_search Scan genome contigs against the ResFinder, PlasmidFinder, and PointFinder antimicrobial resistance databases. Up-to-date https://github.com/phac-nml/staramr Sequence Analysis staramr nml https://github.com/phac-nml/galaxy_tools/tree/master/tools/staramr 0.10.0 staramr 0.10.0 (1/1) (1/1) (1/1) True True -stringmlst stringmlst Rapid and accurate identification of the sequence type (ST) To update Sequence Analysis stringmlst nml 1.1.0 stringMLST 0.6.3 (0/1) (0/1) (0/1) True True -wade wade identify regions of interest To update https://github.com/phac-nml/wade Sequence Analysis wade nml https://github.com/phac-nml/wade 0.2.5+galaxy1 wade 0.2.6 (0/1) (0/1) (0/1) True False -isoplot 2.0 1.0 isoplot Isoplot is a software for the visualisation of MS data from C13 labelling experiments To update Metabolomics, Visualization isoplot workflow4metabolomics https://github.com/llegregam/Isoplot/tree/main 1.3.0+galaxy1 isoplot 1.3.1 (0/1) (0/1) (1/1) True False -repeatexplorer2 repeatexplorer_clustering Tool for annotation of repeats from unassembled shotgun reads. To update https://github.com/repeatexplorer/repex_tarean Genome annotation repeatexplorer2 gga https://github.com/galaxy-genome-annotation/galaxy-tools/tree/master/tools/repeatexplorer2 2.3.8 (0/1) (0/1) (1/1) False -best_regression_subsets 3.0 BestSubsetsRegression1 Perform Best-subsets Regression To update Sequence Analysis, Variant Analysis best_regression_subsets devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/best_regression_subsets 1.0.0 numpy (1/1) (0/1) (1/1) True False -blat_coverage_report generate_coverage_report Polymorphism of the Reads To update Next Gen Mappers, Sequence Analysis blat_coverage_report devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/blat_coverage_report 1.0.0 (0/1) (0/1) (0/1) True False -blat_mapping blat2wig Coverage of the Reads in wiggle format To update Next Gen Mappers, Sequence Analysis blat_mapping devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/blat_mapping 1.0.0 (0/1) (0/1) (0/1) True False -cd_hit_dup cd_hit_dup simple tool for removing duplicates from sequencing reads To update Metagenomics, Sequence Analysis cd_hit_dup devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/cd_hit_dup 0.0.1 cd-hit-auxtools 4.8.1 (1/1) (0/1) (0/1) True True -compute_motif_frequencies_for_all_motifs 94.0 2.0 compute_motif_frequencies_for_all_motifs Compute Motif Frequencies For All Motifs, motif by motif. To update Sequence Analysis, Statistics compute_motif_frequencies_for_all_motifs devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/compute_motif_frequencies_for_all_motifs 1.0.0 (0/1) (1/1) (1/1) True False -compute_motifs_frequency 65.0 compute_motifs_frequency Compute Motif Frequencies in indel flanking regions. To update Sequence Analysis, Statistics compute_motifs_frequency devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/compute_motifs_frequency 1.0.0 (0/1) (1/1) (1/1) True False -count_gff_features 271.0 49.0 count_gff_features Count GFF Features To update Sequence Analysis count_gff_features devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/count_gff_features 0.2 galaxy-ops 1.1.0 (1/1) (1/1) (1/1) True False -ctd_batch 203.0 13.0 ctdBatch_1 CTD analysis of chemicals, diseases, or genes To update Sequence Analysis ctd_batch devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/ctd_batch 1.0.0 (0/1) (0/1) (1/1) True False -cummerbund 1782.0 31.0 cummeRbund Wrapper for the Bioconductor cummeRbund library To update https://bioconductor.org/packages/release/bioc/html/cummeRbund.html RNA, Visualization cummerbund devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/cummerbund 2.16.0 fonts-conda-ecosystem (1/1) (1/1) (1/1) True False -delete_overlapping_indels 39.0 2.0 delete_overlapping_indels Delete Overlapping Indels from a chromosome indels file To update Sequence Analysis delete_overlapping_indels devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/delete_overlapping_indels 1.0.0 (0/1) (0/1) (1/1) True False -divide_pg_snp 31.0 dividePgSnp Separate pgSnp alleles into columns To update Sequence Analysis divide_pg_snp devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/divide_pg_snp 1.0.0 (1/1) (0/1) (1/1) True False -express 325.0 12.0 express Quantify the abundances of a set of target sequences from sampled subsequences To update RNA express devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/express 1.1.1 eXpress 1.5.1 (0/1) (1/1) (1/1) True False -featurecounter 22384.0 6.0 featureCoverage1 Feature coverage To update Sequence Analysis, Variant Analysis featurecounter devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/featurecounter 2.0.0 bx-python 0.11.0 (1/1) (0/1) (1/1) True False -filter_transcripts_via_tracking 20.0 1.0 filter_combined_via_tracking Filter Combined Transcripts To update RNA filter_transcripts_via_tracking devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/filter_transcripts_via_tracking 0.1 (1/1) (1/1) (1/1) True False -generate_pc_lda_matrix 119.0 12.0 generate_matrix_for_pca_and_lda1 Generate a Matrix for using PC and LDA To update Sequence Analysis generate_pc_lda_matrix devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/generate_pc_lda_matrix 1.0.0 (1/1) (1/1) (1/1) True False -getindelrates_3way indelRates_3way Estimate Indel Rates for 3-way alignments To update Sequence Analysis, Variant Analysis getindelrates_3way devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/getindelrates_3way 1.0.0 bx-python 0.11.0 (1/1) (0/1) (0/1) True False -getindels_2way getIndels_2way Fetch Indels from pairwise alignments To update Sequence Analysis, Variant Analysis getindels_2way devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/getindels_2way 1.0.0 numpy (1/1) (0/1) (0/1) True False -gmaj 11.0 4.0 gmaj_1 GMAJ Multiple Alignment Viewer To update Visualization gmaj devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/gmaj 2.0.1 (1/1) (1/1) (1/1) True False -hisat 228.0 hisat HISAT is a fast and sensitive spliced alignment program. To update http://ccb.jhu.edu/software/hisat/index.shtml Assembly hisat devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/hisat 1.0.3 hisat (0/1) (0/1) (0/1) True False -indels_3way 22.0 indels_3way Fetch Indels from 3-way alignments To update Sequence Analysis indels_3way devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/indels_3way 1.0.3 (1/1) (0/1) (1/1) True False -logistic_regression_vif LogisticRegression Perform Logistic Regression with vif To update Sequence Analysis, Variant Analysis, Statistics logistic_regression_vif devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/logistic_regression_vif 1.0.1 numpy (0/1) (0/1) (0/1) True False -maf_cpg_filter cpgFilter Mask CpG/non-CpG sites from MAF file To update Sequence Analysis, Variant Analysis maf_cpg_filter devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/maf_cpg_filter 1.0.0 bx-python 0.11.0 (1/1) (0/1) (0/1) True False -mapping_to_ucsc mapToUCSC Format mapping data as UCSC custom track To update Visualization, Convert Formats, Next Gen Mappers mapping_to_ucsc devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/mapping_to_ucsc 1.0.0 (0/1) (0/1) (0/1) True False -microsatellite_birthdeath microsatellite_birthdeath Identify microsatellite births and deaths To update Sequence Analysis microsatellite_birthdeath devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/microsatellite_birthdeath 1.0.0 (0/1) (0/1) (0/1) True False -microsats_alignment_level microsats_align1 Extract Orthologous Microsatellites from pair-wise alignments To update Sequence Analysis, Variant Analysis microsats_alignment_level devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/microsats_alignment_level 1.0.0 sputnik (1/1) (0/1) (0/1) True False -microsats_mutability microsats_mutability1 Estimate microsatellite mutability by specified attributes To update Sequence Analysis, Variant Analysis microsats_mutability devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/microsats_mutability 1.1.0 bx-python 0.11.0 (1/1) (0/1) (0/1) True False -multispecies_orthologous_microsats multispecies_orthologous_microsats Extract orthologous microsatellites To update Sequence Analysis, Variant Analysis multispecies_orthologous_microsats devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/multispecies_orthologous_microsats 1.0.0 bx-sputnik (0/1) (0/1) (0/1) True True -quality_filter qualityFilter Filter nucleotides based on quality scores To update Sequence Analysis, Variant Analysis quality_filter devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/quality_filter 1.0.1 bx-python 0.11.0 (0/1) (0/1) (0/1) True True -rcve rcve1 Compute RCVE To update Sequence Analysis, Variant Analysis rcve devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/rcve 1.0.0 R (1/1) (0/1) (0/1) True False -short_reads_figure_high_quality_length hist_high_quality_score Histogram of high quality score reads To update Sequence Analysis, Graphics short_reads_figure_high_quality_length devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/short_reads_figure_high_quality_length 1.0.0 rpy (0/1) (0/1) (0/1) True False -short_reads_figure_score 163.0 13.0 quality_score_distribution Build base quality distribution To update Sequence Analysis, Graphics short_reads_figure_score devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/short_reads_figure_score 1.0.2 fontconfig (0/1) (0/1) (1/1) True False -substitution_rates subRate1 Estimate substitution rates for non-coding regions To update Sequence Analysis, Variant Analysis substitution_rates devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/substitution_rates 1.0.0 (0/1) (0/1) (0/1) True False -substitutions substitutions1 Fetch substitutions from pairwise alignments To update Sequence Analysis, Variant Analysis substitutions devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/substitutions 1.0.1 bx-python 0.11.0 (1/1) (0/1) (0/1) True False -tophat 1.0 tophat Tophat for Illumina To update RNA, Next Gen Mappers tophat devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/tophat 1.5.0 samtools 1.19.2 (0/1) (0/1) (0/1) True False -tophat2 24167.0 312.0 tophat2 Tophat - fast splice junction mapper for RNA-Seq reads To update http://ccb.jhu.edu/software/tophat/index.shtml RNA, Next Gen Mappers tophat2 devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/tophat2 2.1.1 bowtie2 2.5.3 (1/1) (1/1) (1/1) True False -ucsc_custom_track 393.0 45.0 build_ucsc_custom_track_1 Build custom track for UCSC genome browser To update Sequence Analysis ucsc_custom_track devteam https://github.com/galaxyproject/tools-devteam/tree/main/tools/ucsc_custom_track 1.0.1 python (1/1) (0/1) (1/1) True False -weightedaverage wtavg Assign weighted-average of the values of features overlapping an interval To update Sequence Analysis, Variant Analysis weightedaverage devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/weightedaverage 1.0.1 galaxy-ops 1.1.0 (1/1) (0/1) (0/1) True False -windowsplitter winSplitter Make windows To update Sequence Analysis, Variant Analysis windowsplitter devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/windowsplitter 1.0.1 bx-python 0.11.0 (1/1) (0/1) (0/1) True False -hgv_fundo hgv_funDo FunDO human genes associated with disease terms To update Sequence Analysis hgv_fundo devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/hgv/hgv_fundo 1.0.0 (1/1) (0/1) (1/1) True False -hgv_hilbertvis hgv_hilbertvis HVIS visualization of genomic data with the Hilbert curve To update https://www.ebi.ac.uk/huber-srv/hilbert/ Graphics, Visualization hgv_hilbertvis devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/hgv/hgv_hilbertvis 1.0.0 R (1/1) (0/1) (1/1) True False -find_diag_hits 69.0 5.0 find_diag_hits Find diagnostic hits To update https://bitbucket.org/natefoo/taxonomy Metagenomics find_diag_hits devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/find_diag_hits 1.0.0 taxonomy 0.10.0 (0/1) (0/1) (1/1) True False -gi2taxonomy 660.0 27.0 Fetch Taxonomic Ranks Fetch taxonomic representation To update https://bitbucket.org/natefoo/taxonomy Metagenomics gi2taxonomy devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/gi2taxonomy 1.1.1 taxonomy 0.10.0 (0/1) (0/1) (1/1) True True -kraken2tax 14683.0 481.0 Kraken2Tax Convert Kraken output to Galaxy taxonomy data. To update https://bitbucket.org/natefoo/taxonomy Metagenomics kraken2tax devteam https://github.com/galaxyproject/tools-devteam/blob/master/tool_collections/taxonomy/kraken2tax/ 1.2+galaxy0 gawk (1/1) (1/1) (1/1) True True -lca_wrapper 137.0 2.0 lca1 Find lowest diagnostic rank To update https://bitbucket.org/natefoo/taxonomy Metagenomics lca_wrapper devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/lca_wrapper 1.0.1 taxonomy 0.10.0 (0/1) (0/1) (1/1) True True -poisson2test 116.0 6.0 poisson2test Poisson two-sample test To update https://bitbucket.org/natefoo/taxonomy Statistics, Metagenomics poisson2test devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/poisson2test 1.0.0 taxonomy 0.10.0 (0/1) (1/1) (1/1) True False -t2ps 457.0 31.0 Draw_phylogram Draw phylogeny To update https://bitbucket.org/natefoo/taxonomy Metagenomics t2ps devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/t2ps 1.0.0 taxonomy 0.10.0 (0/1) (0/1) (1/1) True True -t2t_report 947.0 26.0 t2t_report Summarize taxonomy To update https://bitbucket.org/natefoo/taxonomy Metagenomics t2t_report devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/t2t_report 1.0.0 taxonomy 0.10.0 (0/1) (0/1) (1/1) True True -AggregateAlignments graphclust_aggregate_alignments Aggregate and filter alignment metrics of individual clusters, like the output of graphclust_align_cluster. Up-to-date RNA graphclust_aggregate_alignments rnateam https://github.com/bgruening/galaxytools/tools/GraphClust/AggregateAlignments 0.6.0 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -AlignCluster graphclust_align_cluster Align predicted clusters of glob_report_no_align step with locarna and conservation analysis and visualizations. To update RNA graphclust_align_cluster rnateam https://github.com/bgruening/galaxytools/tools/GraphClust/AlignCluster 0.1 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -CMFinder cmFinder Determines consensus motives for sequences. To update RNA graphclust_cmfinder rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/CMFinder 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -CollectResults glob_report Post-processing. Redundant clusters are merged and instances that belong to multiple clusters are assigned unambiguously. For every pair of clusters, the relative overlap (i.e. the fraction of instances that occur in both clusters) is computed and clusters are merged if the overlap exceeds 50%. instances that occur in both clusters) is computed and clusters are merged if the overlap exceeds 50%. To update RNA graphclust_postprocessing rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/CollectResults 0.5 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -CollectResultsNoAlign graphclust_glob_report_no_align Redundant GraphClust clusters are merged and instances that belong to multiple clusters are assigned unambiguously. To update RNA graphclust_postprocessing_no_align rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/CollectResultsNoAlign 0.5 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -GSPAN gspan Second step of GraphClust To update RNA graphclust_fasta_to_gspan rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/GSPAN 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -LocARNAGraphClust locarna_best_subtree MLocARNA computes a multiple sequence-structure alignment of RNA sequences. To update RNA graphclust_mlocarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/LocARNAGraphClust 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -NSPDK NSPDK_candidateClust, nspdk_sparse Produces an explicit sparse feature encoding and copmutes global feature index and returns top dense sets. To update RNA graphclust_nspdk rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/NSPDK 9.2.3.1 graphclust-wrappers 0.6.0 (0/2) (0/2) (2/2) True False -Plotting motifFinderPlot Plotting results for GraphClust To update RNA graphclust_motif_finder_plot rnateam https://github.com/eteriSokhoyan/galaxytools/tree/master/tools/GraphClust/Plotting 0.4 seaborn (0/1) (0/1) (1/1) True False -PrepareForMlocarna preMloc This tool prepares files for locarna step. To update RNA graphclust_prepocessing_for_mlocarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/PrepareForMlocarna 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -Preprocessing preproc Preprocessing input for GraphClust To update RNA graphclust_preprocessing rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust 0.5 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -Structure_GSPAN structure_to_gspan Convert RNA structure to GSPAN graphs To update RNA structure_to_gspan rnateam https://github.com/mmiladi/galaxytools/blob/graphclust-gspan/tools/GraphClust/Structure_GSPAN 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False -antismash 14596.0 279.0 antismash Antismash allows the genome-wide identification, annotation and analysis of secondary metabolite biosynthesis gene clusters antismash antiSMASH Rapid genome-wide identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genomes. It integrates and cross-links with a large number of in silico secondary metabolite analysis tools that have been published earlier. Sequence clustering, Gene prediction, Differential gene expression analysis Molecular interactions, pathways and networks, Gene and protein families To update https://antismash.secondarymetabolites.org Sequence Analysis antismash bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/antismash 6.1.1 antismash 7.1.0 (1/1) (1/1) (1/1) True True -augustus 8864.0 516.0 augustus AUGUSTUS is a program that predicts genes in eukaryotic genomic sequences. To update http://bioinf.uni-greifswald.de/augustus/ Sequence Analysis augustus bgruening https://github.com/bgruening/galaxytools/tree/master/tools/augustus 3.1.0 augustus 3.5.0 (1/1) (1/1) (1/1) True False -bamhash 169.0 15.0 bamhash Hash BAM and FASTQ files to verify data integrity Up-to-date https://github.com/DecodeGenetics/BamHash Sequence Analysis bamhash bgruening https://github.com/bgruening/galaxytools/tree/master/tools/bamhash 1.1 bamhash 1.1 (0/1) (0/1) (1/1) True False -barcode_collapse barcode_collapse Paired End randomer aware duplicate removal algorithm To update https://github.com/YeoLab/gscripts RNA, Sequence Analysis barcode_collapse rnateam https://github.com/bgruening/galaxytools/tree/master/tools/barcode_collapse 0.1.0 pysam 0.22.0 (0/1) (0/1) (0/1) True False -bionano bionano_scaffold Bionano Solve is a set of tools for analyzing Bionano data To update https://bionanogenomics.com/ Assembly bionano bgruening https://github.com/bgruening/galaxytools/tree/master/tools/bionano 3.7.0 (1/1) (1/1) (1/1) True False -bismark 13575.0 404.0 bismark_pretty_report, bismark_bowtie2, bismark_deduplicate, bismark_methylation_extractor A tool to map bisulfite converted sequence reads and determine cytosine methylation states To update https://www.bioinformatics.babraham.ac.uk/projects/bismark/ Sequence Analysis, Next Gen Mappers bismark bgruening https://github.com/bgruening/galaxytools/tree/master/tools/bismark 0.22.1 bismark 0.24.2 (0/4) (0/4) (4/4) True False -blobtoolkit 685.0 21.0 blobtoolkit Identification and isolation non-target data in draft and publicly available genome assemblies. To update https://blobtoolkit.genomehubs.org/ Sequence Analysis, Assembly blobtoolkit bgruening https://github.com/bgruening/galaxytools/tree/master/tools/blobtoolkit 4.0.7 (0/1) (1/1) (1/1) True False -blockbuster 3009.0 34.0 blockbuster Blockbuster detects blocks of overlapping reads using a gaussian-distribution approach. To update http://hoffmann.bioinf.uni-leipzig.de/LIFE/blockbuster.html RNA, Sequence Analysis blockbuster rnateam https://github.com/bgruening/galaxytools/tree/master/tools/blockbuster 0.1.2 blockbuster 0.0.1.1 (1/1) (1/1) (1/1) True False -chipseeker 15690.0 418.0 chipseeker A tool for ChIP peak annotation and visualization To update https://bioconductor.org/packages/release/bioc/html/ChIPseeker.html ChIP-seq, Genome annotation chipseeker rnateam https://github.com/bgruening/galaxytools/tree/master/tools/chipseeker 1.32.0 bioconductor-chipseeker 1.38.0 (1/1) (1/1) (1/1) True False -circexplorer 251.0 8.0 circexplorer A combined strategy to identify circular RNAs (circRNAs and ciRNAs) To update https://github.com/YangLab/CIRCexplorer Sequence Analysis, RNA circexplorer bgruening https://github.com/bgruening/galaxytools/tree/master/tools/circexplorer 1.1.9.0 circexplorer 1.1.10 (0/1) (1/1) (1/1) True False -combine_metaphlan_humann combine_metaphlan_humann Combine MetaPhlAn2 and HUMAnN2 outputs to relate genus/species abundances and gene families/pathways abundances combine_metaphlan_and_humann Combine Metaphlan and HUMAnN """This tool combine MetaPhlAn outputs and HUMANnN outputs."" - Galaxy tool wrapper" Aggregation Metagenomics, Molecular interactions, pathways and networks To update Metagenomics combine_metaphlan2_humann2 bebatut https://github.com/bgruening/galaxytools/tree/master/tools/combine_metaphlan2_humann2 0.3.0 python (0/1) (0/1) (1/1) True True -compare_humann2_output 332.0 10.0 compare_humann2_output Compare outputs of HUMAnN2 for several samples and extract similar and specific information compare_humann2_outputs Compare HUMAnN2 outputs """This tool compare HUMANnN2 outputs with gene families or pathways and their relative abundances between several samples."" - Galaxy tool wrapper" Comparison Metagenomics, Gene and protein families To update Metagenomics compare_humann2_output bebatut https://github.com/bgruening/galaxytools/tree/master/tools/compare_humann2_output 0.2.0 (0/1) (0/1) (0/1) True True -crt crispr_recognition_tool CRISPR Recognition Tool To update Sequence Analysis crispr_recognition_tool bgruening https://github.com/bgruening/galaxytools/tree/master/tools/crt 1.2.0 crisper_recognition_tool 1.2 (0/1) (0/1) (1/1) True False -flye 20904.0 1499.0 flye Assembly of long and error-prone reads. To update https://github.com/fenderglass/Flye/ Assembly flye bgruening https://github.com/bgruening/galaxytools/tree/master/tools/flye 2.9.1 flye 2.9.3 (1/1) (1/1) (1/1) True True -format_metaphlan2_output 5588.0 166.0 format_metaphlan2_output Format MetaPhlAn2 output to extract abundance at different taxonomic levels format_metaphlan2_output Format metaphlan2 output """This tool format output file of MetaPhlan2 containing community content (abundance) at all taxonomic levels (from kingdom to strains)."" - Galaxy tool wrapper" Formatting Taxonomy, Metagenomics To update Metagenomics format_metaphlan2_output bebatut https://github.com/bgruening/galaxytools/tree/master/tools/format_metaphlan2_output/ 0.2.0 (0/1) (0/1) (1/1) True True -gfastats 8159.0 418.0 gfastats Tool for generating sequence statistics and simultaneous genome assembly file manipulation. gfastats gfastats gfastats is a single fast and exhaustive tool for summary statistics and simultaneous genome assembly file manipulation. gfastats also allows seamless fasta/fastq/gfa conversion. Data handling Computational biology Up-to-date https://github.com/vgl-hub/gfastats Sequence Analysis gfastats bgruening https://github.com/bgruening/galaxytools/tree/master/tools/gfastats 1.3.6 gfastats 1.3.6 (1/1) (1/1) (1/1) True False -glimmer_hmm GlimmerHMM is a new gene finder based on a Generalized Hidden Markov Model (GHMM) To update https://ccb.jhu.edu/software/glimmerhmm/ Sequence Analysis glimmer_hmm bgruening https://github.com/bgruening/galaxytools/tree/master/tools/glimmer_hmm (0/1) (0/1) (0/1) True True -gotohscan 71.0 1.0 rbc_gotohscan Find subsequences in db To update Sequence Analysis gotohscan rnateam https://github.com/bgruening/galaxytools/tree/master/tools/gotohscan 1.3.0 gotohscan 1.3 (0/1) (0/1) (1/1) True False -graphclust 6.0 graphclust GraphClust can be used for structural clustering of RNA sequences. To update http://www.bioinf.uni-freiburg.de/Software/GraphClust/ RNA graphclust bgruening https://github.com/bgruening/galaxytools/tree/master/tools/graphclust 0.1 GraphClust (0/1) (0/1) (0/1) True False -graphmap graphmap_align, graphmap_overlap Mapper for long, error-prone reads. To update https://github.com/isovic/graphmap/ Assembly graphmap bgruening https://github.com/bgruening/galaxytools/tree/master/tools/graphmap 0.5.2 graphmap 0.6.3 (0/2) (0/2) (2/2) True True -hifiasm 1410.0 297.0 hifiasm A fast haplotype-resolved de novo assembler Up-to-date https://github.com/chhylp123/hifiasm Assembly hifiasm bgruening https://github.com/bgruening/galaxytools/tree/master/tools/hifiasm 0.19.8 hifiasm 0.19.8 (1/1) (1/1) (1/1) True False -homer Software for motif discovery and next generation sequencing analysis. To update http://homer.salk.edu/homer/ Sequence Analysis homer bgruening https://github.com/bgruening/galaxytools/tree/master/tools/homer (0/1) (0/1) (0/1) True False -illumina_methylation_analyser illumina_methylation_analyser Methylation analyzer for Illumina 450k DNA emthylation microarrays To update https://github.com/bgruening/galaxytools/tree/master/tools/illumina_methylation_analyser Sequence Analysis illumina_methylation_analyser bgruening https://github.com/bgruening/galaxytools/tree/master/tools/illumina_methylation_analyser 0.1 Rscript (0/1) (0/1) (0/1) True False -instagraal 139.0 14.0 instagraal Large genome reassembly based on Hi-C data instagraal instaGRAAL Chromosome-level quality scaffolding of brown algal genomes using InstaGRAAL.Large genome reassembly based on Hi-C data, continuation of GRAAL.Large genome reassembly based on Hi-C data (continuation and partial rewrite of GRAAL) and post-scaffolding polishing libraries.This work is under continuous development/improvement - see GRAAL for information about the basic principles.sudo pip3 install -e git+https://github.com/koszullab/instagraal.git@master#egg=instagraal.Note to OS X users: There is currently no CUDA support on Mojave (10.14) and it is unclear when it is going to be added, if it is to be added at all. This means instaGRAAL (or indeed any CUDA-based application) will not work on Mojave. If you wish to run it on OS X, the only solution for now is to downgrade to High Sierra (10.13) Genome assembly, Mapping assembly, Genetic mapping, Scaffolding Sequence assembly, Mapping, Metagenomics, Statistics and probability, DNA binding sites To update https://github.com/koszullab/instaGRAAL Assembly instagraal bgruening https://github.com/bgruening/galaxytools/tree/master/tools/instagraal 0.1.6 (0/1) (0/1) (1/1) True False -iprscan5 Interproscan queries the interpro database and provides annotations. To update http://www.ebi.ac.uk/Tools/pfa/iprscan5/ Sequence Analysis iprscan5 bgruening https://github.com/bgruening/galaxytools/tree/master/tools/iprscan5 (0/1) (0/1) (0/1) True True -itsx 868.0 38.0 itsx ITSx is an open source software utility to extract the highly variable ITS1 and ITS2 subregions from ITS sequences. ITSx ITSx TSx is an open source software utility to extract the highly variable ITS1 and ITS2 subregions from ITS sequences, which is commonly used as a molecular barcode for e.g. fungi. As the inclusion of parts of the neighbouring, very conserved, ribosomal genes (SSU, 5S and LSU rRNA sequences) in the sequence identification process can lead to severely misleading results, ITSx identifies and extracts only the ITS regions themselves. Sequence feature detection Functional, regulatory and non-coding RNA, Microbiology Up-to-date https://microbiology.se/software/itsx/ Metagenomics itsx bgruening https://github.com/bgruening/galaxytools/tree/master/tools/itsx 1.1.3 itsx 1.1.3 (0/1) (0/1) (1/1) True True -labels bg_labels remaps and annotates alignments To update https://github.com/bgruening/galaxytools/tree/master/tools/labels Sequence Analysis labels bgruening https://github.com/bgruening/galaxytools/tree/master/tools/labels 1.0.5.0 labels (0/1) (0/1) (0/1) True False -lighter 152.0 9.0 lighter Lighter is a kmer-based error correction method for whole genome sequencing data To update Sequence Analysis, Fasta Manipulation lighter bgruening https://github.com/mourisl/Lighter 1.0 lighter 1.1.2 (0/1) (0/1) (1/1) True True -mafft 143045.0 817.0 rbc_mafft_add, rbc_mafft Multiple alignment program for amino acid or nucleotide sequences MAFFT MAFFT MAFFT (Multiple Alignment using Fast Fourier Transform) is a high speed multiple sequence alignment program. Multiple sequence alignment Sequence analysis To update RNA mafft rnateam https://github.com/bgruening/galaxytools/tree/master/tools/mafft 7.508 mafft 7.520 (2/2) (2/2) (2/2) True True -mcl 29.0 10.0 mcl_clustering Markov Cluster Algorithm To update http://micans.org/mcl/ Sequence Analysis, Metagenomics mcl bgruening https://github.com/bgruening/galaxytools/tree/master/tools/mcl 14.137 mcl 22.282 (0/1) (0/1) (0/1) True True -methtools methtools_calling, r_correlation_matrix, methtools_destrand, methtools_dmr, methtools_filter, methtools_plot, smooth_running_window, methtools_tiling tools for methylation analysis To update https://github.com/bgruening/galaxytools/tree/master/tools/methtools Sequence Analysis methtools bgruening https://github.com/bgruening/galaxytools/tree/master/tools/methtools 0.1.1 methtools (0/8) (0/8) (0/8) True False -methyldackel pileometh A tool for processing bisulfite sequencing alignments To update https://github.com/dpryan79/MethylDackel Sequence Analysis pileometh bgruening https://github.com/bgruening/galaxytools/tree/master/tools/methyldackel 0.5.2 methyldackel 0.6.1 (1/1) (1/1) (1/1) True False -metilene 3966.0 103.0 metilene Differential DNA methylation calling To update RNA, Statistics metilene rnateam https://github.com/bgruening/galaxytools/tree/master/tools/metilene 0.2.6.1 metilene 0.2.8 (1/1) (1/1) (1/1) True False -miclip mi_clip Identification of binding sites in CLIP-Seq data. To update https://cran.r-project.org/src/contrib/Archive/MiClip/ Sequence Analysis miclip bgruening https://github.com/bgruening/galaxytools/tree/master/tools/miclip 1.2.0 Rscript (0/1) (0/1) (0/1) True False -minced 895.0 53.0 minced MinCED - Mining CRISPRs in Environmental Datasets To update http://bioweb2.pasteur.fr/docs/modules/minced/0.1.5/_README Sequence Analysis minced bgruening https://github.com/bgruening/galaxytools/tree/master/tools/minced 0.2.0 minced 0.4.2 (0/1) (0/1) (1/1) True False -minipolish 185.0 21.0 minipolish Polishing miniasm assemblies minipolish minipolish A tool that bridges the output of miniasm (long-read assembly) and racon (assembly polishing) together to polish a draft assembly. It also provides read depth information in contigs. Localised reassembly, Read depth analysis Sequence assembly, Sequencing Up-to-date https://github.com/rrwick/Minipolish Sequence Analysis minipolish bgruening https://github.com/bgruening/galaxytools/tree/master/tools/minipolish 0.1.3 minipolish 0.1.3 (0/1) (0/1) (1/1) True True -mitohifi 613.0 56.0 mitohifi Assembly mitogenomes from Pacbio HiFi read. To update https://github.com/marcelauliano/MitoHiFi/tree/mitohifi_v2 Assembly mitohifi bgruening https://github.com/bgruening/galaxytools/tree/master/tools/mitohifi 3 (1/1) (1/1) (1/1) True False -nextdenovo 268.0 84.0 nextdenovo String graph-based de novo assembler for long reads nextdenovo NextDenovo "NextDenovo is a string graph-based de novo assembler for long reads (CLR, HiFi and ONT). It uses a ""correct-then-assemble"" strategy similar to canu (no correction step for PacBio Hifi reads), but requires significantly less computing resources and storages." De-novo assembly, Genome assembly Sequencing, Sequence assembly To update https://github.com/Nextomics/NextDenovo Assembly nextdenovo bgruening https://github.com/bgruening/galaxytools/tree/master/tools/nextdenovo 2.5.0 nextdenovo 2.5.2 (0/1) (0/1) (1/1) True True -nucleosome_prediction 861.0 2.0 Nucleosome Prediction of Nucleosomes Positions on the Genome Up-to-date https://genie.weizmann.ac.il/software/nucleo_exe.html Sequence Analysis nucleosome_prediction bgruening https://github.com/bgruening/galaxytools/tree/master/tools/nucleosome_prediction 3.0 nucleosome_prediction 3.0 (0/1) (0/1) (1/1) True True -openms AccurateMassSearch, AdditiveSeries, BaselineFilter, CVInspector, CompNovo, CompNovoCID, ConsensusID, ConsensusMapNormalizer, ConvertTSVToTraML, ConvertTraMLToTSV, DTAExtractor, DeMeanderize, Decharger, DecoyDatabase, Digestor, DigestorMotif, EICExtractor, ERPairFinder, ExternalCalibration, FFEval, FalseDiscoveryRate, FeatureFinderCentroided, FeatureFinderIdentification, FeatureFinderIsotopeWavelet, FeatureFinderMRM, FeatureFinderMetabo, FeatureFinderMultiplex, FeatureFinderSuperHirn, FeatureLinkerLabeled, FeatureLinkerUnlabeled, FeatureLinkerUnlabeledQT, FidoAdapter, FileConverter, FileFilter, FileInfo, FileMerger, FuzzyDiff, HighResPrecursorMassCorrector, IDConflictResolver, IDDecoyProbability, IDExtractor, IDFileConverter, IDFilter, IDMapper, IDMassAccuracy, IDMerger, IDPosteriorErrorProbability, IDRTCalibration, IDRipper, IDScoreSwitcher, IDSplitter, ITRAQAnalyzer, InclusionExclusionListCreator, InspectAdapter, InternalCalibration, IsobaricAnalyzer, LabeledEval, LowMemPeakPickerHiRes, LowMemPeakPickerHiRes_RandomAccess, LuciphorAdapter, MRMMapper, MRMPairFinder, MRMTransitionGroupPicker, MSGFPlusAdapter, MSSimulator, MapAlignmentEvaluation, MapNormalizer, MapRTTransformer, MapStatistics, MascotAdapter, MascotAdapterOnline, MassCalculator, MassTraceExtractor, MetaProSIP, MetaboliteSpectralMatcher, MultiplexResolver, MzMLSplitter, MzTabExporter, NoiseFilterGaussian, NoiseFilterSGolay, OpenSwathAnalyzer, OpenSwathAssayGenerator, OpenSwathChromatogramExtractor, OpenSwathConfidenceScoring, OpenSwathDIAPreScoring, OpenSwathDecoyGenerator, OpenSwathFeatureXMLToTSV, OpenSwathFileSplitter, OpenSwathMzMLFileCacher, OpenSwathRTNormalizer, OpenSwathRewriteToFeatureXML, OpenSwathWorkflow, PTModel, PTPredict, PeakPickerHiRes, PeakPickerIterative, PeakPickerWavelet, PepNovoAdapter, PeptideIndexer, PhosphoScoring, PrecursorIonSelector, PrecursorMassCorrector, ProteinInference, ProteinQuantifier, ProteinResolver, QCCalculator, QCEmbedder, QCExporter, QCExtractor, QCImporter, QCMerger, QCShrinker, RNPxl, RNPxlXICFilter, RTEvaluation, RTModel, RTPredict, SemanticValidator, SequenceCoverageCalculator, SimpleSearchEngine, SpecLibCreator, SpectraFilterBernNorm, SpectraFilterMarkerMower, SpectraFilterNLargest, SpectraFilterNormalizer, SpectraFilterParentPeakMower, SpectraFilterScaler, SpectraFilterSqrtMower, SpectraFilterThresholdMower, SpectraFilterWindowMower, SpectraMerger, SvmTheoreticalSpectrumGeneratorTrainer, TICCalculator, TMTAnalyzer, TOFCalibration, TextExporter, TopPerc, TransformationEvaluation, XMLValidator, XTandemAdapter OpenMS in version 2.1. To update Proteomics openms bgruening https://github.com/bgruening/galaxytools/tree/master/tools/openms 2.1.0 openms 3.1.0 (0/140) (34/140) (135/140) True False -peakachu 3109.0 78.0 peakachu PEAKachu is a peak-caller for CLIP- and RIP-Seq data To update Sequence Analysis, RNA peakachu rnateam https://github.com/tbischler/PEAKachu 0.2.0+galaxy1 peakachu 0.2.0 (0/1) (0/1) (1/1) True False -pfamscan 165.0 19.0 pfamscan Search a FASTA sequence against a library of Pfam HMM. pfamscan PfamScan This tool is used to search a FASTA sequence against a library of Pfam HMM. Protein sequence analysis Sequence analysis Up-to-date http://ftp.ebi.ac.uk/pub/databases/Pfam/Tools/ Sequence Analysis pfamscan bgruening https://github.com/bgruening/galaxytools/tree/master/tools/pfamscan 1.6 pfam_scan 1.6 (1/1) (1/1) (1/1) True True -piranha 1809.0 39.0 piranha Piranha is a peak-caller for CLIP- and RIP-Seq data To update Sequence Analysis, RNA piranha rnateam https://github.com/galaxyproject/tools-iuc/tree/master/tools/piranha 1.2.1.0 piranha 1.2.1 (0/1) (0/1) (1/1) True False -platypus bg_platypus efficient and accurate variant-detection in high-throughput sequencing data To update http://www.well.ox.ac.uk/platypus Sequence Analysis platypus bgruening https://github.com/bgruening/galaxytools/tree/master/tools/platypus 0.0.11 platypus (0/1) (0/1) (0/1) True False -plotly_ml_performance_plots 1323.0 71.0 plotly_ml_performance_plots performance plots for machine learning problems To update http://scikit-learn.org/stable/modules/classes.html#module-sklearn.metrics Visualization plotly_ml_performance_plots bgruening https://github.com/bgruening/galaxytools/tree/master/tools/plotly_ml_performance_plots 0.2 pandas (1/1) (1/1) (1/1) True False -plotly_parallel_coordinates_plot 652.0 37.0 plotly_parallel_coordinates_plot parallel coordinates plot produced with plotly To update https://plot.ly/python/parallel-coordinates-plot/ Visualization plotly_parallel_coordinates_plot bgruening https://github.com/bgruening/galaxytools/tree/master/tools/plotly_parallel_coordinates_plot 0.2 python (1/1) (1/1) (1/1) True False -plotly_regression_performance_plots 843.0 79.0 plotly_regression_performance_plots performance plots for regression problems To update http://scikit-learn.org/stable/supervised_learning.html#supervised-learning Visualization plotly_regression_performance_plots bgruening https://github.com/bgruening/galaxytools/tree/master/tools/plotly_regression_performance_plots 0.1 python (1/1) (1/1) (1/1) True False -protease_prediction 149.0 4.0 eden_protease_prediction This tool can learn the cleavage specificity of a given class of proteases. To update https://github.com/fabriziocosta/eden Sequence Analysis, Proteomics protease_prediction bgruening https://github.com/bgruening/galaxytools/tree/master/tools/protease_prediction 0.9 eden 2.0 (0/1) (0/1) (1/1) True False -protein_properties 256.0 15.0 bg_protein_properties Calculation of various properties from given protein sequences To update Sequence Analysis protein_properties bgruening https://github.com/bgruening/galaxytools/tree/master/tools/protein_properties 0.2.0 biopython 1.70 (0/1) (0/1) (1/1) True False -improviser proteomics_improviser Visualisation of PepXML files To update http://www.improviser.uni-freiburg.de/ Proteomics proteomics_improviser bgruening https://github.com/bgruening/galaxytools/tree/master/tools/proteomics/improviser 1.1.0.1 (0/1) (0/1) (0/1) True False -racon 21353.0 309.0 racon Consensus module for raw de novo DNA assembly of long uncorrected reads. Racon Racon The Possibility to Use Oxford Nanopore Technology | Ultrafast consensus module for raw de novo genome assembly of long uncorrected reads. http://genome.cshlp.org/content/early/2017/01/18/gr.214270.116 Note: This was the original repository which will no longer be officially maintained. Please use the new official repository here: https://github.com/isovic/racon| Racon is intended as a standalone consensus module to correct raw contigs generated by rapid assembly methods which do not include a consensus step | Consensus module for raw de novo DNA assembly of long uncorrected reads Genome assembly, Mapping assembly, Sequence trimming Whole genome sequencing, Sequence assembly, Plant biology Up-to-date https://github.com/isovic/racon Sequence Analysis racon bgruening https://github.com/bgruening/galaxytools/tree/master/tools/racon 1.5.0 racon 1.5.0 (1/1) (1/1) (1/1) True True -repeat_masker 3750.0 248.0 repeatmasker_wrapper RepeatMasker is a program that screens DNA sequences for interspersed repeats and low complexity DNA sequences. To update http://www.repeatmasker.org/ Sequence Analysis repeat_masker bgruening https://github.com/bgruening/galaxytools/tree/master/tools/repeat_masker 0.1.2 RepeatMasker 4.1.5 (1/1) (1/1) (1/1) True False -antarna 52.0 2.0 antarna antaRNA uses ant colony optimization to solve the inverse folding problem in RNA research . To update RNA antarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/antarna/ 1.1 antarna 2.0.1.2 (0/1) (0/1) (1/1) True False -aresite2 65.0 4.0 AREsite2_REST AREsite2 REST Interface To update http://rna.tbi.univie.ac.at/AREsite RNA, Data Source, Sequence Analysis aresite2 rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/aresite2 0.1.2 python (0/1) (0/1) (1/1) True False -blockclust 1478.0 15.0 blockclust BlockClust detects transcripts with similar processing patterns. Up-to-date https://github.com/bgruening/galaxytools/tree/master/workflows/blockclust RNA blockclust rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/blockclust 1.1.1 blockclust 1.1.1 (1/1) (1/1) (1/1) True False -cmsearch_deoverlap 102.0 1.0 cmsearch_deoverlap removes lower scoring overlaps from cmsearch results. To update https://github.com/EBI-Metagenomics/pipeline-v5/blob/master/tools/RNA_prediction/cmsearch-deoverlap/cmsearch-deoverlap.pl RNA cmsearch_deoverlap rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/cmsearch_deoverlap 0.08+galaxy0 perl (0/1) (0/1) (1/1) True False -cmv 70.0 1.0 cmcv, cmv, hmmcv, hmmv cmv is a collection of tools for the visualisation of Hidden Markov Models and RNA-family models. Up-to-date https://github.com/eggzilla/cmv RNA cmv rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/cmv 1.0.8 cmv 1.0.8 (0/4) (0/4) (2/4) True False -cofold 342.0 8.0 cofold Cofold predicts RNA secondary structures that takes co-transcriptional folding into account. To update http://www.e-rna.org/cofold/ RNA cofold rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/cofold 2.0.4.0 cofold 2.0.4 (0/1) (0/1) (1/1) True False -compalignp 220.0 compalignp Compute fractional identity between trusted alignment and test alignment Up-to-date RNA, Sequence Analysis compalignp rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/compalignp/ 1.0 compalignp 1.0 (0/1) (0/1) (1/1) True False -coprarna coprarna Target prediction for prokaryotic trans-acting small RNAs To update https://github.com/PatrickRWright/CopraRNA RNA, Sequence Analysis coprarna rnateam https://github.com/PatrickRWright/CopraRNA 2.1.1 coprarna 2.1.4 (0/1) (0/1) (0/1) True False -dewseq 72.0 11.0 dewseq DEWSeq is a sliding window based peak caller for eCLIP/iCLIP data To update https://github.com/EMBL-Hentze-group/DEWSeq_analysis_helpers Sequence Analysis, RNA, CLIP-seq dewseq rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/dewseq 0.1.0+galaxy0 python (0/1) (0/1) (1/1) True False -dorina 1086.0 1.0 dorina_search data source for RNA interactions in post-transcriptional regulation To update RNA, Data Source dorina rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/dorina/ 1.0 (0/1) (0/1) (1/1) True False -dot2ct rnastructure_dot2ct Dot-Bracket to Connect Table (CT) To update Sequence Analysis, RNA dot2ct rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/dot2ct 5.7.a rnastructure 6.4 (0/1) (0/1) (0/1) True False -dotknot 83.0 1.0 dotknot DotKnot is a heuristic method for pseudoknot prediction in a given RNA sequence To update http://dotknot.csse.uwa.edu.au/ RNA, Proteomics dotknot bgruening https://github.com/bgruening/galaxytools/tree/master/tools/rna/dotknot 1.3.1 vienna_rna (0/1) (0/1) (1/1) True False -exparna exparna ExpaRNA is a fast, motif-based comparison and alignment tool for RNA molecules. Up-to-date http://rna.informatik.uni-freiburg.de/ExpaRNA/Input.jsp RNA exparna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/exparna 1.0.1 exparna 1.0.1 (0/1) (0/1) (0/1) True False -graphprot graphprot_predict_profile GraphProt models binding preferences of RNA-binding proteins. To update https://github.com/dmaticzka/GraphProt Sequence Analysis, RNA, CLIP-seq graphprot rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/graphprot 1.1.7+galaxy1 graphprot 1.1.7 (0/1) (0/1) (1/1) True False -htseq-clip htseq_clip htseq-clip is a toolset for the analysis of eCLIP/iCLIP datasets To update https://github.com/EMBL-Hentze-group/htseq-clip Sequence Analysis, RNA, CLIP-seq htseq_clip rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/htseq-clip 0.1.0+galaxy0 htseq-clip 2.19.0b0 (0/1) (0/1) (1/1) True False -infernal 100230.0 67.0 infernal_cmalign, infernal_cmbuild, infernal_cmpress, infernal_cmscan, infernal_cmsearch, infernal_cmstat "Infernal (""INFERence of RNA ALignment"") is for searching DNA sequence databases for RNA structure and sequence similarities." infernal Infernal "Infernal (""INFERence of RNA ALignment"") is for searching DNA sequence databases for RNA structure and sequence similarities. It is an implementation of a special case of profile stochastic context-free grammars called covariance models (CMs). A CM is like a sequence profile, but it scores a combination of sequence consensus and RNA secondary structure consensus, so in many cases, it is more capable of identifying RNA homologs that conserve their secondary structure more than their primary sequence." Nucleic acid feature detection Sequence sites, features and motifs To update http://infernal.janelia.org/ RNA infernal bgruening https://github.com/bgruening/galaxytools/tree/master/tools/infernal 1.1.4 infernal 1.1.5 (0/6) (6/6) (6/6) True True -inforna INFO-RNA is a service for the design of RNA sequences that fold into a given pseudo-knot free RNA secondary structure. To update http://rna.informatik.uni-freiburg.de/INFORNA/Input.jsp RNA inforna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/inforna (0/1) (0/1) (0/1) True False -intarna 7569.0 23.0 intarna Efficient RNA-RNA interaction prediction incorporating accessibility and seeding of interaction sites. Up-to-date https://github.com/BackofenLab/IntaRNA RNA intarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/intarna 3.4.0 intarna 3.4.0 (0/1) (0/1) (1/1) True False -kinwalker 70.0 3.0 Kinwalker splits the folding process into a series of events where each event can either be a folding event or a transcription event. To update http://www.bioinf.uni-leipzig.de/Software/Kinwalker/ RNA kinwalker rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/kinwalker (0/1) (0/1) (0/1) True False -locarna locarna_exparnap, locarna_multiple, locarna_pairwise, locarna_pairwise_p, locarna_reliability_profile LocARNA - A suite for multiple alignment and folding of RNAs To update http://www.bioinf.uni-freiburg.de/Software/LocARNA/ RNA locarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/locarna 1.9.2.3 locarna 2.0.0 (0/5) (0/5) (1/5) True False -mea 85.0 3.0 mea Maximum expected accuracy prediction To update http://www.bioinf.uni-leipzig.de/Software/mea RNA mea rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/mea 0.6.4.1 mea 0.6.4 (0/1) (0/1) (1/1) True False -mqc 76.0 5.0 mqc Ribosome profiling mapping quality control tool To update https://github.com/Biobix/mQC Sequence Analysis mqc rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/mqc/ 1.9 mqc 1.10 (0/1) (0/1) (1/1) True False -nastiseq 40.0 nastiseq A method to identify cis-NATs using ssRNA-seq Up-to-date https://ohlerlab.mdc-berlin.de/software/NASTIseq_104/ RNA nastiseq rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/nastiseq 1.0 r-nastiseq 1.0 (0/1) (0/1) (1/1) True False -paralyzer 299.0 7.0 paralyzer A method to generate a high resolution map of interaction sites between RNA-binding proteins and their targets. Up-to-date https://ohlerlab.mdc-berlin.de/software/PARalyzer_85/ RNA paralyzer rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/paralyzer 1.5 paralyzer 1.5 (0/1) (0/1) (1/1) True False -pipmir 275.0 21.0 pipmir A method to identify novel plant miRNA. To update https://ohlerlab.mdc-berlin.de/software/Pipeline_for_the_Identification_of_Plant_miRNAs_84/ RNA pipmir rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/pipmir 0.1.0 pipmir 1.1 (0/1) (0/1) (1/1) True False -rRNA meta_rna Identification of ribosomal RNA genes in metagenomic fragments. To update http://weizhong-lab.ucsd.edu/meta_rna/ RNA rrna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rRNA 0.1 hmmsearch3.0 (0/1) (0/1) (0/1) True True -rbpbench 36.0 rbpbench Evaluate CLIP-seq and other genomic region data using a comprehensive collection of RBP binding motifs rbpbench RBPBench Evaluate CLIP-seq and other genomic region data using a comprehensive collection of RBP binding motifs RNA, Protein interactions, RNA immunoprecipitation, Bioinformatics, Sequence analysis Up-to-date https://github.com/michauhl/RBPBench Sequence Analysis, RNA, CLIP-seq rbpbench rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rbpbench 0.8.1 rbpbench 0.8.1 (0/1) (0/1) (1/1) False -rcas 1226.0 38.0 rcas RCAS (RNA Centric Annotation System) for functional analysis of transcriptome-wide regions detected by high-throughput experiments To update https://github.com/BIMSBbioinfo/RCAS RNA rcas rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rcas/ 1.5.4 bioconductor-rcas 1.28.2 (0/1) (0/1) (1/1) True False -reago reago Reago is tool to assembly 16S ribosomal RNA recovery from metagenomic data. Up-to-date https://github.com/chengyuan/reago-1.1 Metagenomics, RNA reago rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/reago 1.1 reago 1.1 (0/1) (0/1) (0/1) True True -remurna 42.0 2.0 remurna remuRNA - Measurement of Single Nucleotide Polymorphism induced Changes of RNA Conformation To update https://www.ncbi.nlm.nih.gov/CBBresearch/Przytycka/index.cgi#remurna RNA remurna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/remurna 1.0.0 remurna 1.0 (0/1) (0/1) (1/1) True False -ribotaper 628.0 44.0 ribotaper_create_annotation, ribotaper_create_metaplots, ribotaper_ribosome_profiling A method for defining traslated ORFs using Ribosome Profiling data. ribotaper RiboTaper New analysis pipeline for Ribosome Profiling (Ribo-seq) experiments, which exploits the triplet periodicity of ribosomal footprints to call translated regions. Gene expression profiling Functional genomics To update https://ohlerlab.mdc-berlin.de/software/RiboTaper_126/ RNA ribotaper rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/ribotaper/ 1.3.1a ribotaper 1.3.1 (0/3) (0/3) (3/3) True False -rna_shapes RNAshapes Compute secondary structures of RNA To update RNA rnashapes rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rna_shapes 3.3.0 @EXECUTABLE@ (0/1) (0/1) (1/1) True False -rnabob 164.0 3.0 rbc_rnabob Fast pattern searching for RNA structural motifs To update http://eddylab.org/software.html RNA rnabob rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rnabob 2.2.1.0 rnabob 2.2.1 (0/1) (0/1) (1/1) True False -rnacode 1358.0 5.0 rbc_rnacode Analyze the protein coding potential in MSA To update RNA rnacode rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rnacode 0.3.2 rnacode 0.3 (0/1) (0/1) (1/1) True False -rnacommender 1074.0 6.0 rbc_rnacommender RNAcommender is a tool for genome-wide recommendation of RNA-protein interactions. To update https://github.com/gianlucacorrado/RNAcommender RNA rnacommender rnateam https://github.com/bgruening/galaxytools/tree/rna_commander/tools/rna_tools/rna_commender 0.1.1 sam 3.5 (0/1) (0/1) (1/1) True False -rnalien 33.0 4.0 RNAlien RNAlien unsupervized RNA family model construction To update http://rna.tbi.univie.ac.at/rnalien/ RNA, Sequence Analysis rnalien rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rnalien 1.3.6 rnalien 1.8.0 (0/1) (0/1) (1/1) True False -rnasnp 86.0 5.0 rnasnp RNAsnp Efficient detection of local RNA secondary structure changes induced by SNPs To update http://rth.dk/resources/rnasnp/ RNA rnasnp rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rnasnp 1.2.0 rnasnp 1.2 (0/1) (0/1) (1/1) True False -rnaz 42965.0 14.0 rnaz, rnaz_annotate, rnaz_cluster, rnaz_randomize_aln, rnaz_select_seqs, rnaz_window RNAz is a program for predicting structurally conserved and thermodynamically stable RNA secondary structures in multiple sequence alignments. Up-to-date https://www.tbi.univie.ac.at/~wash/RNAz/ RNA rnaz bgruening https://github.com/bgruening/galaxytools/tree/master/tools/rna_team/rnaz 2.1.1 rnaz 2.1.1 (0/6) (0/6) (6/6) True False -selectsequencesfrommsa 457.0 27.0 selectsequencesfrommsa SelectSequences - selects representative entries from a multiple sequence alignment in clustal format Up-to-date https://github.com/eggzilla/SelectSequences RNA, Sequence Analysis selectsequencesfrommsa rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/selectsequencesfrommsa 1.0.5 selectsequencesfrommsa 1.0.5 (0/1) (0/1) (1/1) True False -sortmerna 18504.0 376.0 bg_sortmerna SortMeRNA is a software designed to rapidly filter ribosomal RNA fragments from metatransriptomic data produced by next-generation sequencers. sortmerna SortMeRNA Sequence analysis tool for filtering, mapping and OTU-picking NGS reads. Sequence similarity search, Sequence comparison, Sequence alignment analysis Metatranscriptomics, Metagenomics Up-to-date http://bioinfo.lifl.fr/RNA/sortmerna/ RNA sortmerna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/sortmerna 4.3.6 sortmerna 4.3.6 (1/1) (1/1) (1/1) True True -sshmm 223.0 5.0 sshmm ssHMM is an RNA sequence-structure motif finder for RNA-binding protein data, such as CLIP-Seq data Up-to-date https://github.molgen.mpg.de/heller/ssHMM Sequence Analysis, RNA sshmm rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/sshmm/ 1.0.7 sshmm 1.0.7 (0/1) (0/1) (1/1) True False -targetfinder 713.0 37.0 targetfinder Plant small RNA target prediction tool Up-to-date https://github.com/carringtonlab/TargetFinder.git RNA targetfinder rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/targetfinder/ 1.7 targetfinder 1.7 (1/1) (1/1) (1/1) True False -trna_prediction 2935.0 236.0 aragorn_trna, trnascan Aragorn predicts tRNA and tmRNA in nucleotide sequences. To update http://mbioserv2.mbioekol.lu.se/ARAGORN/ RNA trna_prediction bgruening https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/trna_prediction 0.6 aragorn 1.2.41 (0/2) (2/2) (2/2) True False -vienna_rna 799.0 viennarna_kinfold, viennarna_kinwalker, viennarna_rna2dfold, viennarna_rnaaliduplex, viennarna_rnaalifold, viennarna_rnacofold, viennarna_rnadistance, viennarna_rnaduplex, viennarna_rnaeval, viennarna_rnafold, viennarna_rnaheat, viennarna_rnainverse, viennarna_rnalalifold, viennarna_rnalfold, viennarna_rnapaln, viennarna_rnadpdist, viennarna_rnapkplex, viennarna_rnaplex, viennarna_rnaplfold, viennarna_rnaplot, viennarna_rnasnoop, viennarna_rnasubopt, viennarna_rnaup ViennaRNA - Prediction and comparison of RNA secondary structures To update http://www.tbi.univie.ac.at/RNA/ RNA viennarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/vienna_rna 2.2.10 viennarna 2.6.4 (0/23) (0/23) (21/23) True False -sailfish 4024.0 55.0 sailfish Sailfish is a tool for transcript quantification from RNA-seq data To update http://www.cs.cmu.edu/~ckingsf/software/sailfish/ Sequence Analysis, RNA sailfish bgruening https://github.com/bgruening/galaxytools/tree/master/tools/sailfish 0.10.1.1 bzip2 (1/1) (1/1) (1/1) True False -salmon 55161.0 746.0 alevin, salmon, salmonquantmerge Salmon is a wicked-fast program to produce a highly-accurate, transcript-level quantification estimates from RNA-seq and single-cell data. To update https://github.com/COMBINE-lab/salmon Sequence Analysis, RNA, Transcriptomics bgruening https://github.com/bgruening/galaxytools/tree/master/tools/salmon 1.10.1 salmon 1.10.2 (2/3) (1/3) (3/3) True True -tapscan tapscan_classify Search for transcription associated proteins (TAPs) To update https://plantcode.cup.uni-freiburg.de/tapscan/ Proteomics tapscan bgruening https://github.com/bgruening/galaxytools/tree/master/tools/tapscan 4.76+galaxy0 hmmer 3.4 (0/1) (0/1) (1/1) False -tgsgapcloser 460.0 36.0 tgsgapcloser TGS-GapCloser uses error-prone long reads or preassembled contigs to fill N-gap in the genome assembly. TGS-GapCloser TGS-GapCloser TGS-GapCloser is a fast and accurately passing through the Bermuda in large genome using error-prone third-generation long reads. Genome assembly, Read mapping, Scaffolding, Localised reassembly Sequencing, Sequence assembly, Phylogeny, Transcription factors and regulatory sites, Mapping To update https://github.com/BGI-Qingdao/TGS-GapCloser Assembly tgsgapcloser bgruening https://github.com/bgruening/galaxytools/tree/master/tools/tgsgapcloser 1.0.3 tgsgapcloser 1.2.1 (0/1) (0/1) (1/1) True False -trim_galore 238699.0 2334.0 trim_galore Trim Galore adaptive quality and adapter trimmer trim_galore Trim Galore A wrapper tool around Cutadapt and FastQC to consistently apply quality and adapter trimming to FastQ files, with some extra functionality for MspI-digested RRBS-type (Reduced Representation Bisufite-Seq) libraries. Sequence trimming Sequence analysis To update http://www.bioinformatics.babraham.ac.uk/projects/trim_galore/ Sequence Analysis, Fastq Manipulation trim_galore bgruening https://github.com/bgruening/galaxytools/tree/master/tools/trim_galore 0.6.7 trim-galore 0.6.10 (1/1) (1/1) (1/1) True True -uniprot_rest_interface 2406.0 132.0 uniprot UniProt ID mapping and sequence retrieval To update https://github.com/jdrudolph/uniprot Proteomics, Sequence Analysis uniprot_rest_interface bgruening https://github.com/bgruening/galaxytools/tree/master/tools/uniprot_rest_interface 0.4 requests (1/1) (1/1) (1/1) True False -vt vt_@BINARY@, vt_@BINARY@ A tool set for short variant discovery in genetic sequence data. To update Sequence Analysis, Variant Analysis vt bgruening https://github.com/atks/vt 0.2 vt 2015.11.10 (0/1) (0/1) (0/1) True False -wtdbg 1660.0 116.0 wtdbg WTDBG is a fuzzy Bruijn graph (FBG) approach to long noisy reads assembly. wtdbg2 wtdbg2 Wtdbg2 is a de novo sequence assembler for long noisy reads produced by PacBio or Oxford Nanopore Technologies (ONT). It assembles raw reads without error correction and then builds the consensus from intermediate assembly output. Wtdbg2 is able to assemble the human and even the 32Gb Axolotl genome at a speed tens of times faster than CANU and FALCON while producing contigs of comparable base accuracy. Genome assembly, De-novo assembly Sequence assembly, Sequencing Up-to-date https://github.com/ruanjue/wtdbg2 Assembly wtdbg bgruening https://github.com/bgruening/galaxytools/tree/master/tools/wtdbg 2.5 wtdbg 2.5 (0/1) (0/1) (1/1) True True -align_back_trans 329.0 11.0 align_back_trans Thread nucleotides onto a protein alignment (back-translation) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/align_back_trans Fasta Manipulation, Sequence Analysis align_back_trans peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/align_back_trans 0.0.10 biopython 1.70 (0/1) (0/1) (1/1) True False -chromosome_diagram chromosome_diagram Chromosome Diagrams using Biopython To update Graphics, Sequence Analysis, Visualization chromosome_diagram peterjc 0.0.3 biopython 1.70 (0/1) (0/1) (0/1) True False -clc_assembly_cell clc_assembler, clc_mapper Galaxy wrapper for the CLC Assembly Cell suite from CLCBio To update https://github.com/peterjc/pico_galaxy/tree/master/tools/clc_assembly_cell Assembly, Next Gen Mappers, SAM clc_assembly_cell peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/clc_assembly_cell 0.0.7 samtools 1.19.2 (0/2) (0/2) (0/2) True False -clinod clinod NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins To update http://www.compbio.dundee.ac.uk/www-nod/ Sequence Analysis clinod peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/clinod 0.1.0 clinod 1.3 (1/1) (0/1) (0/1) True True -count_roi_variants count_roi_variants Count sequence variants in region of interest in BAM file To update https://github.com/peterjc/pico_galaxy/tree/master/tools/count_roi_variants Assembly, SAM count_roi_variants peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/count_roi_variants 0.0.6 samtools 1.19.2 (0/1) (0/1) (0/1) True False -coverage_stats coverage_stats BAM coverage statistics using samtools idxstats and depth To update https://github.com/peterjc/pico_galaxy/tree/master/tools/coverage_stats Assembly, SAM coverage_stats peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/coverage_stats 0.1.0 samtools 1.19.2 (0/1) (0/1) (0/1) True False -effectiveT3 effectiveT3 Find bacterial type III effectors in protein sequences To update http://effectors.org Sequence Analysis effectivet3 peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/effectiveT3 0.0.20 effectiveT3 1.0.1 (0/1) (0/1) (0/1) True True -fasta_filter_by_id fasta_filter_by_id Filter FASTA sequences by ID (DEPRECATED) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/fasta_filter_by_id Fasta Manipulation, Sequence Analysis, Text Manipulation fasta_filter_by_id peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/fasta_filter_by_id 0.0.7 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False -fastq_filter_by_id fastq_filter_by_id Filter FASTQ sequences by ID (DEPRECATED) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_filter_by_id Fastq Manipulation, Sequence Analysis, Text Manipulation fastq_filter_by_id peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_filter_by_id 0.0.7 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False -fastq_pair_names fastq_pair_names Extract FASTQ paired read names To update https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_pair_names Sequence Analysis fastq_pair_names peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_pair_names 0.0.5 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False -fastq_paired_unpaired fastq_paired_unpaired Divide FASTQ file into paired and unpaired reads To update https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_paired_unpaired Sequence Analysis, Text Manipulation fastq_paired_unpaired peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_paired_unpaired 0.1.5 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False -get_orfs_or_cdss 7.0 get_orfs_or_cdss Search nucleotide sequences for open reading frames (ORFs), or coding sequences (CDSs) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/get_orfs_or_cdss Sequence Analysis get_orfs_or_cdss peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/get_orfs_or_cdss 0.2.3 biopython 1.70 (0/1) (1/1) (1/1) True False -mummer 652.0 83.0 mummerplot_wrapper Draw dotplots using mummer, mucmer, or promer with mummerplot To update http://mummer.sourceforge.net/ Graphics, Sequence Analysis, Visualization mummer peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/mummer 0.0.8 ghostscript 9.18 (1/1) (0/1) (1/1) True False -nlstradamus nlstradamus Find nuclear localization signals (NLSs) in protein sequences To update http://www.moseslab.csb.utoronto.ca/NLStradamus Fasta Manipulation, Sequence Analysis nlstradamus peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/nlstradamus 0.0.11 NLStradamus 1.8 (0/1) (0/1) (0/1) True False -predictnls predictnls Python reimplementation of predictNLS for Galaxy To update https://github.com/peterjc/pico_galaxy/tree/master/tools/predictnls Sequence Analysis predictnls peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/predictnls 0.0.10 (0/1) (0/1) (0/1) True False -protein_analysis promoter2, Psortb, rxlr_motifs, signalp3, tmhmm2, wolf_psort TMHMM, SignalP, Promoter, RXLR motifs, WoLF PSORT and PSORTb To update https://github.com/peterjc/pico_galaxy/tree/master/tools/protein_analysis Sequence Analysis tmhmm_and_signalp peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/protein_analysis 0.0.13 promoter (0/6) (0/6) (6/6) True False -sample_seqs 3765.0 149.0 sample_seqs Sub-sample sequences files (e.g. to reduce coverage) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/sample_seqs Assembly, Fasta Manipulation, Fastq Manipulation, Sequence Analysis sample_seqs peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/sample_seqs 0.2.6 biopython 1.70 (1/1) (1/1) (1/1) True False -samtools_depad samtools_depad Re-align a SAM/BAM file with a padded reference (using samtools depad) To update http://www.htslib.org/ Assembly, SAM, Sequence Analysis samtools_depad peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/samtools_depad 0.0.5 samtools 1.19.2 (0/1) (0/1) (0/1) True False -samtools_depth 4948.0 296.0 samtools_depth Coverage depth via samtools To update http://www.htslib.org/ Assembly, Sequence Analysis, SAM samtools_depth peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/samtools_depth 0.0.3 samtools 1.19.2 (1/1) (1/1) (1/1) True False -samtools_idxstats 48426.0 1450.0 samtools_idxstats BAM mapping statistics (using samtools idxstats) To update http://www.htslib.org/ Assembly, Next Gen Mappers, SAM samtools_idxstats peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/samtools_idxstats 0.0.6 samtools 1.19.2 (1/1) (1/1) (1/1) True False -seq_composition 874.0 71.0 seq_composition Sequence composition To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_composition Sequence Analysis seq_composition peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_composition 0.0.5 biopython 1.70 (1/1) (0/1) (1/1) True False -seq_filter_by_id 25302.0 306.0 seq_filter_by_id Filter sequences by ID To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_filter_by_id Fasta Manipulation, Sequence Analysis, Text Manipulation seq_filter_by_id peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_filter_by_id 0.2.9 biopython 1.70 (1/1) (1/1) (1/1) True False -seq_filter_by_mapping 3784.0 82.0 seq_filter_by_mapping Filter sequencing reads using SAM/BAM mapping files To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_filter_by_mapping Assembly, Fasta Manipulation, Fastq Manipulation, SAM, Sequence Analysis seq_filter_by_mapping peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_filter_by_mapping 0.0.8 biopython 1.70 (0/1) (0/1) (1/1) True False -seq_length seq_length Compute sequence length (from FASTA, QUAL, FASTQ, SFF, etc) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_length Fasta Manipulation, Fastq Manipulation, Sequence Analysis seq_length peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_length 0.0.5 biopython 1.70 (0/1) (0/1) (0/1) True False -seq_primer_clip seq_primer_clip Trim off 5' or 3' primers To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_primer_clip Assembly, Fasta Manipulation, Text Manipulation seq_primer_clip peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_primer_clip 0.0.18 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False -seq_rename seq_rename Rename sequences with ID mapping from a tabular file To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_rename Fasta Manipulation, Sequence Analysis, Text Manipulation seq_rename peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_rename 0.0.10 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False -seq_select_by_id seq_select_by_id Select sequences by ID To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_select_by_id Fasta Manipulation, Sequence Analysis, Text Manipulation seq_select_by_id peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_select_by_id 0.0.15 biopython 1.70 (0/1) (1/1) (0/1) True False -venn_list 5067.0 248.0 venn_list Draw Venn Diagram (PDF) from lists, FASTA files, etc To update https://github.com/peterjc/pico_galaxy/tree/master/tools/venn_list Graphics, Sequence Analysis, Visualization venn_list peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/venn_list 0.1.2 galaxy_sequence_utils 1.1.5 (1/1) (0/1) (1/1) True False -TrimNs trimns TrimNs is used to trim and remove fake cut sites from bionano hybrid scaffold data in the VGP pipeline To update https://github.com/VGP/vgp-assembly/tree/master/pipeline/bionano/trimNs Assembly trimns iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/trimN 0.1.0 trimns_vgp 1.0 (0/1) (0/1) (1/1) True False -abricate 496717.0 1764.0 abricate, abricate_list, abricate_summary Mass screening of contigs for antiobiotic resistance genes ABRicate ABRicate Mass screening of contigs for antimicrobial resistance or virulence genes. Antimicrobial resistance prediction Genomics, Microbiology Up-to-date https://github.com/tseemann/abricate Sequence Analysis abricate iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/abricate/ 1.0.1 abricate 1.0.1 (3/3) (3/3) (3/3) True True -abritamr abritamr A pipeline for running AMRfinderPlus and collating results into functional classes Up-to-date https://zenodo.org/record/7370628 Sequence Analysis abritamr iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/abritamr 1.0.14 abritamr 1.0.14 (0/1) (0/1) (0/1) True True -abyss 4278.0 391.0 abyss-pe Assembly By Short Sequences - a de novo, parallel, paired-end sequence assembler abyss ABySS De novo genome sequence assembler using short reads. Genome assembly, De-novo assembly, Scaffolding Sequence assembly Up-to-date http://www.bcgsc.ca/platform/bioinfo/software/abyss Assembly abyss iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/abyss 2.3.7 abyss 2.3.7 (0/1) (1/1) (1/1) True True -adapter_removal 217.0 37.0 adapter_removal Removes residual adapter sequences from single-end (SE) or paired-end (PE) FASTQ reads. adapterremoval AdapterRemoval AdapterRemoval searches for and removes adapter sequences from High-Throughput Sequencing (HTS) data and (optionally) trims low quality bases from the 3' end of reads following adapter removal. AdapterRemoval can analyze both single end and paired end data, and can be used to merge overlapping paired-ended reads into (longer) consensus sequences. Additionally, AdapterRemoval can construct a consensus adapter sequence for paired-ended reads, if which this information is not available. Sequence trimming, Sequence merging, Primer removal Up-to-date https://github.com/MikkelSchubert/adapterremoval Fasta Manipulation, Sequence Analysis adapter_removal iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/adapter_removal/ 2.3.3 adapterremoval 2.3.3 (0/1) (0/1) (1/1) True False -aegean aegean_canongff3, aegean_gaeval, aegean_locuspocus, aegean_parseval AEGeAn toolkit wrappers gaeval GAEVAL Gene Annotation EVAluation. Sequence annotation Sequence analysis, Gene structure Up-to-date https://github.com/BrendelGroup/AEGeAn Transcriptomics, Sequence Analysis aegean iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/aegean 0.16.0 aegean 0.16.0 (1/4) (4/4) (4/4) True False -aldex2 129.0 13.0 aldex2 Performs analysis Of differential abundance taking sample variation into account aldex2 ALDEx2 A differential abundance analysis for the comparison of two or more conditions. It uses a Dirichlet-multinomial model to infer abundance from counts, that has been optimized for three or more experimental replicates. Infers sampling variation and calculates the expected FDR given the biological and sampling variation using the Wilcox rank test and Welches t-test, or the glm and Kruskal Wallis tests. Reports both P and fdr values calculated by the Benjamini Hochberg correction. Statistical inference Gene expression, Statistics and probability To update https://github.com/ggloor/ALDEx_bioc Metagenomics aldex2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/aldex2 1.26.0 bioconductor-aldex2 1.34.0 (0/1) (0/1) (1/1) True True -amplican 53.0 12.0 amplican AmpliCan is an analysis tool for genome editing. amplican amplican It performs alignment of the amplicon reads, normalizes gathered data, calculates multiple statistics (e.g. cut rates, frameshifts) and presents results in form of aggregated reports. Data and statistics can be broken down by experiments, barcodes, user defined groups, guides and amplicons allowing for quick identification of potential problems. Alignment, Standardisation and normalisation PCR experiment, Statistics and probability To update https://github.com/valenlab/amplican Sequence Analysis amplican iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/amplican 1.14.0 bioconductor-amplican 1.24.0 (0/1) (0/1) (1/1) True True -ampvis2 ampvis2_alpha_diversity, ampvis2_boxplot, ampvis2_core, ampvis2_export_fasta, ampvis2_frequency, ampvis2_heatmap, ampvis2_load, ampvis2_merge_ampvis2, ampvis2_mergereplicates, ampvis2_octave, ampvis2_ordinate, ampvis2_otu_network, ampvis2_rankabundance, ampvis2_rarecurve, ampvis2_setmetadata, ampvis2_subset_samples, ampvis2_subset_taxa, ampvis2_timeseries, ampvis2_venn ampvis2 ampvis ampvis ampvis2 is an R-package to conveniently visualise and analyse 16S rRNA amplicon data in different ways. Analysis, Visualisation Biodiversity To update https://github.com/MadsAlbertsen/ampvis2/ Metagenomics ampvis2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ampvis2 2.8.6 (0/19) (0/19) (19/19) True False -amrfinderplus 591.0 amrfinderplus """AMRFinderPlus is designed to find acquired antimicrobial resistance genes and point mutations in protein and/or assembled nucleotide sequences.It can also search ""plus"", stress, heat, and biocide resistance and virulence factors for some organisms." amrfinderplus AMRFinderPlus "AMRFinderPlus is designed to find acquired antimicrobial resistance genes and point mutations in protein and/or assembled nucleotide sequences.It can also search ""plus"", stress, heat, and biocide resistance and virulence factors for some organisms" Antimicrobial resistance prediction Microbiology, Public health and epidemiology, Infectious disease To update https://github.com/ncbi/amr Sequence Analysis AMRFinderPlus iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/amrfinderplus 3.11.26 ncbi-amrfinderplus 3.12.8 (0/1) (0/1) (1/1) True True -ancombc 7.0 4.0 ancombc Performs analysis of compositions of microbiomes with bias correction. ancombc ANCOMBC Determine taxa whose absolute abundances, per unit volume, of the ecosystem (e.g. gut) are significantly different with changes in the covariate of interest (e.g. group). The current version of ancombc function implements Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC) in cross-sectional data while allowing for covariate adjustment. DNA barcoding Microbial ecology, Metagenomics To update https://github.com/FrederickHuangLin/ANCOMBC Metagenomics ancombc iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ancombc 1.4.0 bioconductor-ancombc 2.4.0 (0/1) (0/1) (1/1) True True -anndata anndata_export, anndata_import, anndata_inspect, anndata_manipulate, modify_loom Import, Export, Inspect and Manipulate Anndata and Loom objects To update https://anndata.readthedocs.io Transcriptomics, Sequence Analysis anndata iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/anndata/ 0.10.3 anndata 0.6.22.post1 (5/5) (4/5) (5/5) True False -annotatemyids 26115.0 1175.0 annotatemyids annotateMyIDs: get annotation for a set of IDs using the Bioconductor annotation packages annotatemyids annotatemyids This tool can get annotation for a generic set of IDs, using the Bioconductor annotation data packages. Supported organisms are human, mouse, rat, fruit fly and zebrafish. The org.db packages that are used here are primarily based on mapping using Entrez Gene identifiers. More information on the annotation packages can be found at the Bioconductor website, for example, information on the human annotation package (org.Hs.eg.db) can be found here. Annotation Up-to-date https://github.com/galaxyproject/tools-iuc/tree/master/tools/annotatemyids Genome annotation annotatemyids iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/annotatemyids 3.18.0 bioconductor-org.hs.eg.db 3.18.0 (1/1) (1/1) (1/1) True False -arriba 3436.0 28.0 arriba, arriba_draw_fusions, arriba_get_filters Arriba detects fusion genes in RNA-Seq data after running RNA-STAR Up-to-date https://github.com/suhrig/arriba Sequence Analysis, Transcriptomics arriba iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/arriba 2.4.0 arriba 2.4.0 (0/3) (3/3) (3/3) True False -art art_454, art_illumina, art_solid Simulator for Illumina, 454, and SOLiD sequencing data art ART ART is a set of simulation tools to generate synthetic next-generation sequencing reads. ART simulates sequencing reads by mimicking real sequencing process with empirical error models or quality profiles summarized from large recalibrated sequencing data. ART can also simulate reads using user own read error model or quality profiles. ART supports simulation of single-end, paired-end/mate-pair reads of three major commercial next-generation sequencing platforms. Illuminas Solexa, Roches 454 and Applied Biosystems SOLiD Conversion Bioinformatics To update Sequence Analysis, Data Source art iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/art 2014.11.03.0 art 2016.06.05 (0/3) (0/3) (0/3) True False -artic artic_guppyplex, artic_minion The artic pipeline is designed to help run the artic bioinformatics protocols;for example the nCoV-2019 novel coronavirus protocol.Features include: read filtering, primer trimming, amplicon coverage normalisation,variant calling and consensus building artic ARTIC A bioinformatics pipeline for working with virus sequencing data sequenced with nanopore Sequence alignment Genomics To update https://github.com/artic-network/fieldbioinformatics Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/artic artic 1.2.4 (0/2) (0/2) (2/2) True True -assembly-stats assembly_stats Assembly metric visualisations to facilitate rapid assessment and comparison of assembly quality. Up-to-date https://github.com/rjchallis/assembly-stats Assembly assembly_stats iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/assembly-stats 17.02 rjchallis-assembly-stats 17.02 (0/1) (0/1) (0/1) True False -augustus 8864.0 516.0 augustus, augustus_training AUGUSTUS is a program that predicts genes in eukaryotic genomic sequences. augustus AUGUSTUS AUGUSTUS is a eukaryotic gene prediction tool. It can integrate evidence, e.g. from RNA-Seq, ESTs, proteomics, but can also predict genes ab initio. The PPX extension to AUGUSTUS can take a protein sequence multiple sequence alignment as input to find new members of the family in a genome. It can be run through a web interface (see https://bio.tools/webaugustus), or downloaded and run locally. Gene prediction, Ab-initio gene prediction, Homology-based gene prediction, Homology-based gene prediction, Operation Gene transcripts, Gene and protein families To update http://bioinf.uni-greifswald.de/augustus/ Sequence Analysis augustus bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/augustus 3.4.0 augustus 3.5.0 (2/2) (2/2) (2/2) True False -b2btools b2btools_single_sequence This software suite provides structural predictions for protein sequences made by Bio2Byte group.About Bio2Byte: We investigate how the dynamics, conformational states, and available experimental data of proteins relate to their amino acid sequence.Underlying physical and chemical principles are computationally unraveled through data integration, analysis, and machine learning, so connecting themto biological events and improving our understanding of the way proteins work. b2btools b2bTools The bio2byte tools server (b2btools) offers the following single protein sequence based predictions:- Backbone and sidechain dynamics (DynaMine)- Helix, sheet, coil and polyproline-II propensity- Early folding propensity (EFoldMine)- Disorder (DisoMine)- Beta-sheet aggregation (Agmata)In addition, multiple sequence alignments (MSAs) can be uploaded to scan the 'biophysical limits' of a protein family as defined in the MSA Protein disorder prediction, Protein secondary structure prediction, Protein feature detection To update https://bio2byte.be Computational chemistry, Molecular Dynamics, Proteomics, Sequence Analysis, Synthetic Biology iuc 3.0.5+galaxy0 b2btools 3.0.6 (0/1) (0/1) (1/1) True False -bakta 2982.0 151.0 bakta """Bakta is a tool for the rapid & standardized annotation of bacterial genomes and plasmids from both isolates and MAGs.It provides dbxref-rich and sORF-including annotations in machine-readable JSON & bioinformatics standard file formats for automatic downstream analysis.""" Bakta Bakta Rapid & standardized annotation of bacterial genomes, MAGs & plasmids Genome annotation Genomics, Data submission, annotation and curation, Sequence analysis Up-to-date https://github.com/oschwengers/bakta Sequence Analysis bakta iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/bakta 1.9.2 bakta 1.9.2 (0/1) (1/1) (1/1) True True -bamutil bamutil_clip_overlap, bamutil_diff bamUtil is a repository that contains several programs that perform operations on SAM/BAM files. To update https://github.com/statgen/bamUtil Sequence Analysis bamutil iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bamutil bamutil 1.0.15 (1/2) (1/2) (1/2) True False -bandage 44390.0 2016.0 bandage_image, bandage_info Bandage - A Bioinformatics Application for Navigating De novo Assembly Graphs Easily bandage Bandage GUI program that allows users to interact with the assembly graphs made by de novo assemblers such as Velvet, SPAdes, MEGAHIT and others. It visualises assembly graphs, with connections, using graph layout algorithms. Sequence assembly visualisation Genomics, Sequence assembly Up-to-date https://github.com/rrwick/Bandage Visualization bandage iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bandage 2022.09 bandage_ng 2022.09 (2/2) (2/2) (2/2) True True -baredsc baredsc_1d, baredsc_2d, baredsc_combine_1d, baredsc_combine_2d baredSC is a tool that uses a Monte-Carlo Markov Chain to estimate a confidence interval on the probability density function (PDF) of expression of one or two genes from single-cell RNA-seq data. baredsc baredSC The baredSC (Bayesian Approach to Retreive Expression Distribution of Single Cell) is a tool that uses a Monte-Carlo Markov Chain to estimate a confidence interval on the probability density function (PDF) of expression of one or two genes from single-cell RNA-seq data. Data retrieval, Expression correlation analysis, Differential gene expression profiling RNA-Seq, Cytometry, Transcriptomics, Gene transcripts, Statistics and probability Up-to-date https://github.com/lldelisle/baredSC Transcriptomics, Visualization baredsc iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/baredsc 1.1.2 baredsc 1.1.2 (4/4) (0/4) (4/4) True False -barrnap 3938.0 160.0 barrnap Contains the Barrnap tool for finding ribosomal RNAs in FASTA sequences. barrnap Barrnap Predict the location of ribosomal RNA genes in genomes. It supports bacteria (5S,23S,16S), archaea (5S,5.8S,23S,16S), mitochondria (12S,16S) and eukaryotes (5S,5.8S,28S,18S). Gene prediction Genomics, Model organisms, Model organisms To update Sequence Analysis barrnap iuc 1.2.2 barrnap 0.9 (0/1) (1/1) (1/1) True False -bax2bam 200.0 8.0 bax2bam BAX to BAM converter Up-to-date https://github.com/pacificbiosciences/bax2bam/ Convert Formats, Sequence Analysis bax2bam iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pax2bam 0.0.11 bax2bam 0.0.11 (1/1) (0/1) (1/1) True False -bayescan 64.0 8.0 BayeScan Detecting natural selection from population-based genetic data bayescan BayeScan BAYEsian genome SCAN for outliers, aims at identifying candidate loci under natural selection from genetic data, using differences in allele frequencies between populations. It is based on the multinomial-Dirichlet model. Statistical inference Genetics, Evolutionary biology, Statistics and probability, DNA polymorphism To update http://cmpg.unibe.ch/software/BayeScan/index.html Sequence Analysis bayescan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bayescan/ 2.1 bayescan 2.0.1 (0/1) (0/1) (1/1) True True -bbtools bbtools_bbduk, bbtools_bbmap, bbtools_bbmerge, bbtools_bbnorm, bbtools_callvariants, bbtools_tadpole BBTools is a suite of fast, multithreaded bioinformatics tools designed for analysis of DNA and RNA sequence data.BBTools can handle common sequencing file formats such as fastq, fasta, sam, scarf, fasta+qual, compressed or raw,with autodetection of quality encoding and interleaving. It is written in Java and works on any platform supportingJava, including Linux, MacOS, and Microsoft Windows and Linux; there are no dependencies other than Java (version7 or higher). Program descriptions and options are shown when running the shell scripts with no parameters. Up-to-date https://jgi.doe.gov/data-and-tools/bbtools/ Sequence Analysis bbtools iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bbtools 39.06 bbmap 39.06 (6/6) (1/6) (5/6) True False -bctools bctools_convert_to_binary_barcode, bctools_extract_crosslinked_nucleotides, bctools_extract_alignment_ends, bctools_extract_barcodes, bctools_merge_pcr_duplicates, bctools_remove_tail, bctools_remove_spurious_events bctools is a set of tools for handling barcodes and UMIs in NGS data.bctools can be used to merge PCR duplicates according to unique molecular barcodes (UMIs),to extract barcodes from arbitrary positions relative to the read starts,to clean up readthroughs into UMIs with paired-end sequencing andhandles binary barcodes as used with uvCLAP and FLASH.License: Apache License 2.0 Up-to-date https://github.com/dmaticzka/bctools Sequence Analysis, Transcriptomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bedtools 0.2.2 bctools 0.2.2 (0/7) (0/7) (7/7) True False -bellerophon 1194.0 123.0 bellerophon Filter mapped reads where the mapping spans a junction, retaining the 5-prime read. Up-to-date https://github.com/davebx/bellerophon Sequence Analysis bellerophon iuc https://github.com/davebx/bellerophon 1.0 bellerophon 1.0 (1/1) (1/1) (1/1) True False -bigscape bigscape Construct sequence similarity networks of BGCs and groups them into GCF Up-to-date https://github.com/medema-group/BiG-SCAPE Metagenomics bigscape iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bigscape/ 1.1.9 bigscape 1.1.9 (0/1) (0/1) (0/1) False -binning_refiner 81.0 21.0 bin_refiner Reconciles the outputs of different binning programs with the aim to improve the quality of genome bins,especially with respect to contamination levels. binning_refiner Binning_refiner Improving genome bins through the combination of different binning programs Read binning, Sequence clustering Metagenomics Up-to-date https://github.com/songweizhi/Binning_refiner Metagenomics binning_refiner iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/binning_refiner/ 1.4.3 binning_refiner 1.4.3 (0/1) (0/1) (1/1) True True -bioinformatics_cafe fasta_regex_finder Miscellanea of scripts for bioinformatics To update https://github.com/dariober/bioinformatics-cafe/ Sequence Analysis bioinformatics_cafe mbernt https://github.com/galaxyproject/tools-iuc/tree/main/tools/bioinformatics-cafe 0.1.0 python (1/1) (0/1) (1/1) True False -biom_format biom_add_metadata, biom_convert, biom_from_uc, biom_normalize_table, biom_subset_table, biom_summarize_table The biom-format package provides a command line interface and Python API for working with BIOM files. biomformat biomformat "This package includes basic tools for reading biom-format files, accessing and subsetting data tables from a biom object, as well as limited support for writing a biom-object back to a biom-format file. The design of this API is intended to match the python API and other tools included with the biom-format project, but with a decidedly ""R flavor"" that should be familiar to R users. This includes S4 classes and methods, as well as extensions of common core functions/methods." Formatting Laboratory information management, Sequence analysis To update https://github.com/biocore/biom-format Metagenomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/biom_format 2.1.15 biom-format 2.1.7 (2/6) (2/6) (1/6) True True -bioperl bp_genbank2gff3 Converts GenBank format files to GFF3 bioperl BioPerl A collection of Perl modules that facilitate the development of Perl scripts for bioinformatics applications. It provides software modules for many of the typical tasks of bioinformatics programming. Data handling, Service invocation Genomics, Software engineering, Data management To update https://bioperl.org/ Sequence Analysis bp_genbank2gff3 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bioperl 1.1 perl-bioperl 1.7.8 (1/1) (1/1) (1/1) True False -biscot 3.0 1.0 biscot Bionano scaffolding correction tool Up-to-date https://github.com/institut-de-genomique/biscot Assembly biscot iuc https://github.com/bgruening/iuc/tree/master/tools/biscot 2.3.3 biscot 2.3.3 (0/1) (0/1) (1/1) True False -blastxml_to_gapped_gff3 185.0 24.0 blastxml_to_gapped_gff3 BlastXML to gapped GFF3 To update Convert Formats, Sequence Analysis blastxml_to_gapped_gff3 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/blastxml_to_gapped_gff3 1.1 bcbiogff 0.6.6 (1/1) (1/1) (1/1) True False -bracken 18351.0 326.0 est_abundance Bayesian Reestimation of Abundance with KrakEN bracken Bracken Statistical method that computes the abundance of species in DNA sequences from a metagenomics sample. Statistical calculation Metagenomics, Microbial ecology Up-to-date https://ccb.jhu.edu/software/bracken/ Sequence Analysis, Metagenomics bracken iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bracken 2.9 bracken 2.9 (0/1) (0/1) (1/1) True True -busco 86180.0 1804.0 busco BUSCO assess genome and annotation completeness busco BUSCO Provides measures for quantitative assessment of genome assembly, gene set, and transcriptome completeness based on evolutionarily informed expectations of gene content from near-universal single-copy orthologs. Sequence assembly validation, Scaffolding, Genome assembly, Transcriptome assembly Sequence assembly, Genomics, Transcriptomics, Sequence analysis To update https://gitlab.com/ezlab/busco/-/releases Sequence Analysis busco iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/busco/ 5.5.0 busco 5.6.1 (1/1) (1/1) (1/1) True True -bwameth 10619.0 201.0 bwameth Fast and accurate alignment of BS-seq reads To update https://github.com/brentp/bwa-meth Sequence Analysis, Next Gen Mappers bwameth iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bwameth 0.2.6 bwameth 0.2.7 (1/1) (1/1) (1/1) True False -cactus cactus_cactus, cactus_export Cactus is a reference-free whole-genome multiple alignment program cactus Cactus Cactus is a reference-free whole-genome multiple alignment program. Multiple sequence alignment, Genome alignment Genomics, Sequence analysis, Phylogeny, Sequence assembly, Mapping, Phylogenetics To update https://github.com/ComparativeGenomicsToolkit/cactus Sequence Analysis cactus galaxy-australia https://github.com/galaxyproject/tools-iuc/tree/main/tools/cactus 2.7.1 (0/2) (2/2) (2/2) False -calculate_contrast_threshold calculate_contrast_threshold Calculates a contrast threshold from the CDT file generated by ``tag_pileup_frequency``. The calculated values are then used to set a uniform contrast for all the heatmaps generated downstream. To update https://github.com/CEGRcode/ChIP-QC-tools/tree/master/calculate_contrast_threshold Visualization, Genomic Interval Operations, SAM calculate_contrast_threshold iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/calculate_contrast_threshold 1.0.0 numpy (0/1) (0/1) (0/1) True False -cat cat_add_names, cat_bins, cat_contigs, cat_prepare, cat_summarise Contig Annotation Tool (CAT) cat_bins CAT and BAT Contig Annotation Tool (CAT) and Bin Annotation Tool (BAT) are pipelines for the taxonomic classification of long DNA sequences and metagenome assembled genomes (MAGs/bins) of both known and (highly) unknown microorganisms, as generated by contemporary metagenomics studies. The core algorithm of both programs involves gene calling, mapping of predicted ORFs against the nr protein database, and voting-based classification of the entire contig / MAG based on classification of the individual ORFs. Taxonomic classification, Sequence assembly, Coding region prediction Metagenomics, Metagenomic sequencing, Taxonomy, Sequence assembly To update https://github.com/dutilh/CAT Metagenomics contig_annotation_tool iuc https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/cat 5.2.3 cat 5.3 (5/5) (2/5) (5/5) True True -cdhit 8278.0 6.0 cd_hit Cluster or compare biological sequence datasets cd-hit cd-hit Cluster a nucleotide dataset into representative sequences. Sequence clustering Sequencing Up-to-date http://weizhongli-lab.org/cd-hit/ Sequence Analysis, Fasta Manipulation cd_hit iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/cdhit 4.8.1 cd-hit 4.8.1 (0/1) (0/1) (1/1) True True -cemitool 98.0 9.0 cemitool Gene co-expression network analysis tool cemitool CEMiTool It unifies the discovery and the analysis of coexpression gene modules in a fully automatic manner, while providing a user-friendly html report with high quality graphs. Our tool evaluates if modules contain genes that are over-represented by specific pathways or that are altered in a specific sample group. Additionally, CEMiTool is able to integrate transcriptomic data with interactome information, identifying the potential hubs on each network. Enrichment analysis, Pathway or network analysis Gene expression, Transcriptomics, Microarray experiment To update https://www.bioconductor.org/packages/release/bioc/html/CEMiTool.html Transcriptomics, RNA, Statistics cemitool iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/cemitool 1.18.1 bioconductor-cemitool 1.26.0 (1/1) (0/1) (1/1) True True -charts 3589.0 287.0 charts Enables advanced visualization options in Galaxy Charts To update Visualization charts iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/charts/ 1.0.1 r-getopt (0/1) (0/1) (0/1) True False -checkm checkm_analyze, checkm_lineage_set, checkm_lineage_wf, checkm_plot, checkm_qa, checkm_taxon_set, checkm_taxonomy_wf, checkm_tetra, checkm_tree, checkm_tree_qa Assess the quality of microbial genomes recovered from isolates, single cells, and metagenomes checkm CheckM CheckM provides a set of tools for assessing the quality of genomes recovered from isolates, single cells, or metagenomes. Operation Genomics, Phylogenomics, Phylogenetics, Taxonomy, Metagenomics To update https://github.com/Ecogenomics/CheckM Metagenomics checkm iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/checkm 1.2.0 checkm-genome 1.2.2 (0/10) (0/10) (10/10) True True -cherri cherri_eval, cherri_train Computational Help Evaluating RNA-RNA interactions cherri cherri CheRRI detects functional RNA-RNA interaction (RRI) sites, by evaluating if an interaction site most likely occurs in nature. It helps to filter interaction sites generated either experimentally or by an RRI prediction algorithm by removing false positive interactions. Molecular interactions, pathways and networks, Structure analysis, Machine learning To update https://github.com/BackofenLab/Cherri Transcriptomics, RNA iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/cherri 0.7 cherri 0.8 (0/2) (0/2) (2/2) True False -chira 74.0 chira_collapse, chira_extract, chira_map, chira_merge, chira_quantify Chimeric Read Annotator for RNA-RNA interactome data chira ChiRA ChiRA is a tool suite to analyze RNA-RNA interactome experimental data such as CLASH, CLEAR-CLIP, PARIS, SPLASH, etc. RNA, Molecular interactions, pathways and networks, Functional, regulatory and non-coding RNA Up-to-date https://github.com/pavanvidem/chira RNA, Transcriptomics, Sequence Analysis chira iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/chira 1.4.3 chira 1.4.3 (5/5) (0/5) (5/5) True False -chromeister 2130.0 182.0 chromeister ultra-fast pairwise genome comparisons Up-to-date https://github.com/estebanpw/chromeister Sequence Analysis chromeister iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/chromeister 1.5.a chromeister 1.5.a (0/1) (1/1) (1/1) True False -circexplorer2 269.0 16.0 circexplorer2 Comprehensive and integrative circular RNA analysis toolset. circexplorer2 CIRCexplorer2 Genome-wide annotation of circRNAs and their alternative back-splicing/splicing. RNA splicing, Gene transcripts, Literature and language Up-to-date https://github.com/YangLab/CIRCexplorer2 RNA, Assembly circexplorer2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/circexplorer2 2.3.8 circexplorer2 2.3.8 (0/1) (0/1) (1/1) True False -clair3 1856.0 68.0 clair3 Symphonizing pileup and full-alignment for high-performance long-read variant calling clair3 Clair3 Clair3 is a germline small variant caller for long-reads. Clair3 makes the best of two major method categories: pileup calling handles most variant candidates with speed, and full-alignment tackles complicated candidates to maximize precision and recall. Clair3 runs fast and has superior performance, especially at lower coverage. Clair3 is simple and modular for easy deployment and integration. Variant calling Molecular genetics To update https://github.com/HKU-BAL/Clair3 Sequence Analysis, Variant Analysis clair3 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/clair3 0.1.12 clair3 1.0.5 (0/1) (0/1) (1/1) True False +Galaxy wrapper id Total tool usage (usegalaxy.eu) No. of tool users (2022-2023) (usegalaxy.eu) Galaxy tool ids Description bio.tool id bio.tool name bio.tool description EDAM operation EDAM topic Status Source ToolShed categories ToolShed id Galaxy wrapper owner Galaxy wrapper source Galaxy wrapper version Conda id Conda version https://usegalaxy.org https://usegalaxy.org.au https://usegalaxy.eu Reviewed To keep +braker 109.0 17.0 braker BRAKER is a pipeline for fully automated prediction of protein coding gene structures with GeneMark-ES/ET and AUGUSTUS in novel eukaryotic genomes . To update https://github.com/Gaius-Augustus/BRAKER Genome annotation braker genouest https://github.com/genouest/galaxy-tools/tree/master/tools/braker 2.1.6 (0/1) (0/1) (1/1) True False +braker3 567.0 10.0 braker3 BRAKER3 is a pipeline for fully automated prediction of protein coding gene structures with GeneMark-ES/ET and AUGUSTUS in novel eukaryotic genomes . To update https://github.com/Gaius-Augustus/BRAKER Genome annotation braker3 genouest https://github.com/genouest/galaxy-tools/tree/master/tools/braker 3.0.8 (0/1) (1/1) (1/1) True False +helixer 93.0 1.0 helixer Gene calling with Deep Neural Networks To update https://github.com/weberlab-hhu/Helixer Genome annotation helixer genouest https://github.com/genouest/galaxy-tools/tree/master/tools/helixer 0.3.2 (0/1) (0/1) (1/1) True False +logol logol_wrapper Logol is a pattern matching grammar language and a set of tools to search a pattern in a sequence Up-to-date http://logol.genouest.org/web/app.php/logol Sequence Analysis genouest https://github.com/genouest/galaxy-tools/tree/master/tools/logol 1.7.8 logol 1.7.8 (0/1) (0/1) (0/1) True False +peptimapper peptimapper_clustqualify, peptimapper_clust_to_gff, peptimapper_pep_match, peptimapper_pep_novo_tag Proteogenomics workflow for the expert annotation of eukaryotic genomes To update https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5431-9 Proteomics genouest 2.0 (0/4) (0/4) (0/4) True False +GAFA gafa Gene Align and Family Aggregator To update http://aequatus.tgac.ac.uk Visualization gafa earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/GAFA/ 0.3.1 (0/1) (0/1) (1/1) True False +TreeBest treebest_best TreeBeST best To update http://treesoft.sourceforge.net/treebest.shtml Phylogenetics treebest_best earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/TreeBest 1.9.2.post0 treebest 1.9.2.post1 (0/1) (0/1) (1/1) True True +blast_parser 296.0 27.0 blast_parser Convert 12- or 24-column BLAST output into 3-column hcluster_sg input To update https://github.com/TGAC/earlham-galaxytools/ Phylogenetics blast_parser earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/blast_parser 0.1.2 (0/1) (0/1) (1/1) True False +ete 1255.0 67.0 ete_gene_csv_finder, ete_genetree_splitter, ete_homology_classifier, ete_init_taxdb, ete_lineage_generator, ete3_mod, ete_species_tree_generator Analyse phylogenetic trees using the ETE Toolkit To update http://etetoolkit.org/ Phylogenetics ete earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/ete 3.1.2 ete3 3.1.1 (0/7) (0/7) (7/7) True True +gblocks gblocks Gblocks Up-to-date http://molevol.cmima.csic.es/castresana/Gblocks.html Sequence Analysis gblocks earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/gblocks 0.91b gblocks 0.91b (0/1) (1/1) (0/1) True False +hcluster_sg 238.0 13.0 hcluster_sg Hierarchically clustering on a sparse graph To update https://github.com/douglasgscofield/hcluster Phylogenetics hcluster_sg earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/hcluster_sg 0.5.1.1 hcluster_sg 0.5.1 (0/1) (0/1) (1/1) True False +hcluster_sg_parser 290.0 7.0 hcluster_sg_parser Converts hcluster_sg 3-column output into lists of ids To update https://github.com/TGAC/earlham-galaxytools/ Phylogenetics hcluster_sg_parser earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/hcluster_sg_parser 0.2.1 (0/1) (0/1) (1/1) True False +lotus2 936.0 114.0 lotus2 LotuS2 OTU processing pipeline lotus2 lotus2 LotuS2 is a lightweight and user-friendly pipeline that is fast, precise, and streamlined, using extensive pre- and post-ASV/OTU clustering steps to further increase data quality. High data usage rates and reliability enable high-throughput microbiome analysis in minutes. Sequence feature detection Metagenomics Up-to-date http://lotus2.earlham.ac.uk/ Metagenomics lotus2 earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/lotus2 2.32 lotus2 2.32 (0/1) (0/1) (1/1) True True +miranda 6076.0 41.0 miranda Finds potential target sites for miRNAs in genomic sequences To update http://www.microrna.org/ RNA miranda earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/miranda 3.3a+galaxy1 miranda 3.3a (0/1) (0/1) (1/1) True False +smart_domains smart_domains SMART domains To update http://smart.embl.de/ Sequence Analysis smart_domains earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/smart_domains 0.1.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False +t_coffee 8690.0 70.0 t_coffee T-Coffee To update http://www.tcoffee.org/ Sequence Analysis t_coffee earlhaminst https://github.com/TGAC/earlham-galaxytools/tree/master/tools/t_coffee 13.45.0.4846264 t-coffee 13.46.0.919e8c6b (0/1) (0/1) (1/1) True False +abacas abacas Order and Orientate Contigs To update https://github.com/phac-nml/abacas Assembly abacas nml https://github.com/phac-nml/abacas 1.1 mummer 3.23 (0/1) (0/1) (0/1) True True +assemblystats assemblystats Summarise an assembly (e.g. N50 metrics) To update https://github.com/phac-nml/galaxy_tools Assembly assemblystats nml https://github.com/phac-nml/galaxy_tools 1.1.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True True +bam2mappingstats bam2mappingstats Generates mapping stats from a bam file. To update https://github.com/phac-nml/galaxy_tools Assembly bam2mappingstats nml https://github.com/phac-nml/galaxy_tools 1.1.0 perl (0/1) (0/1) (0/1) True False +bamclipper bamclipper Soft-clip gene-specific primers from BAM alignment file based on genomic coordinates of primer pairs in BEDPE format. Up-to-date https://github.com/tommyau/bamclipper Sequence Analysis bamclipper nml https://github.com/tommyau/bamclipper 1.0.0 bamclipper 1.0.0 (0/1) (0/1) (0/1) True False +biohansel biohansel Heidelberg and Enteritidis SNP Elucidation To update https://github.com/phac-nml/biohansel Sequence Analysis biohansel nml https://github.com/phac-nml/biohansel 2.4.0 bio_hansel 2.6.1 (0/1) (0/1) (0/1) True True +bundle_collections bundle_collection Tool to bundle up list collection into a single zip to be download To update Sequence Analysis bundle_collections nml 1.3.0 perl-getopt-long 2.54 (0/1) (1/1) (0/1) True False +collapse_collection collapse_dataset Collection tool that collapses a list of files into a single datasset in order of appears in collection To update Sequence Analysis collapse_collections nml 5.1.0 gawk (1/1) (1/1) (1/1) True False +combineJSON combine_json JSON collection tool that takes multiple JSON data arrays and combines them into a single JSON array. To update Sequence Analysis combine_json nml 0.1 (0/1) (0/1) (0/1) True False +combine_assembly_stats combine_stats Combine multiple Assemblystats datasets into a single tabular report To update https://github.com/phac-nml/galaxy_tools Assembly combine_assemblystats nml https://github.com/phac-nml/galaxy_tools 1.0 perl-getopt-long 2.54 (0/1) (0/1) (0/1) True True +combine_tabular_collection combine Combine Tabular Collection into a single file To update Sequence Analysis combine_tabular_collection nml 0.1 (0/1) (0/1) (0/1) True False +cryptogenotyper 8518.0 16.0 CryptoGenotyper CryptoGenotyper is a standalone tool to *in-silico* determine species and subtype based on SSU rRNA and gp60 markers. Up-to-date https://github.com/phac-nml/CryptoGenotyper Sequence Analysis cryptogenotyper nml https://github.com/phac-nml/CryptoGenotyper 1.0 cryptogenotyper 1.0 (0/1) (0/1) (1/1) True True +ectyper 9907.0 53.0 ectyper EC-Typer - in silico serotyping of Escherichia coli species Up-to-date https://github.com/phac-nml/ecoli_serotyping Sequence Analysis ectyper nml https://github.com/phac-nml/ecoli_serotyping 1.0.0 ectyper 1.0.0 (0/1) (0/1) (1/1) True True +fasta2bed fasta2bed Convert multiple fasta file into tabular bed file format To update https://github.com/phac-nml/galaxy_tools Sequence Analysis fasta2bed nml https://github.com/phac-nml/galaxy_tools 1.0.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False +fasta_extract 10.0 fa-extract-sequence extract single fasta from multiple fasta file To update https://toolshed.g2.bx.psu.edu/view/nml/fasta_extract Sequence Analysis fasta_extract nml https://toolshed.g2.bx.psu.edu/view/nml/fasta_extract 1.1.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False +fastqc_stats FastQC_Summary Summary multiple FastQC into a single tabular line report To update https://github.com/phac-nml/galaxy_tools Sequence Analysis fastqc_stats nml https://github.com/phac-nml/galaxy_tools 1.2 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False +feht feht Automatically identify makers predictive of groups. To update https://github.com/phac-nml/galaxy_tools Sequence Analysis feht nml https://github.com/phac-nml/galaxy_tools 0.1.0 feht 1.1.0 (0/1) (0/1) (0/1) True False +filter_spades_repeats filter_spades_repeat Remove short and repeat contigs/scaffolds To update https://github.com/phac-nml/galaxy_tools/ Assembly filter_spades_repeats nml https://github.com/phac-nml/galaxy_tools/ 1.0.1 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True True +getmlst getmlst Download MLST datasets by species from pubmlst.org To update Sequence Analysis getmlst nml 0.1.4.1 srst2 0.2.0 (0/1) (0/1) (0/1) True True +hivtrace hivtrace An application that identifies potential transmission clusters within a supplied FASTA file with an option to find potential links against the Los Alamos HIV Sequence Database. To update Sequence Analysis hivtrace nml https://github.com/phac-nml/galaxy_tools/tree/tools/hivtrace 1.0.1 hivtrace 1.5.0 (0/1) (0/1) (0/1) True True +kaptive kaptive Kaptive reports information about capsular (K) loci found in genome assemblies. To update Sequence Analysis kaptive nml 0.3.0 kaptive 2.0.6 (0/1) (0/1) (0/1) True False +kat_filter kat_@EXECUTABLE@ Filtering kmers or reads from a database of kmers hashes To update Sequence Analysis kat_filter nml 2.3 kat 2.4.2 (0/1) (0/1) (0/1) True True +mauve_contig_mover mauve_contig_mover Order a draft genome relative to a related reference genome To update https://github.com/phac-nml/mauve_contig_mover Sequence Analysis mauve_contig_mover nml https://github.com/phac-nml/mauve_contig_mover 1.0.10 mauve 2.4.0.r4736 (0/1) (0/1) (0/1) True False +mob_suite 89021.0 322.0 mob_recon, mob_typer MOB-suite is a set of software tools for clustering, reconstruction and typing of plasmids from draft assemblies To update https://github.com/phac-nml/mob-suite Sequence Analysis mob_suite nml https://github.com/phac-nml/mob-suite 3.0.3 mob_suite 3.1.8 (0/2) (2/2) (2/2) True True +mrbayes mrbayes A program for the Bayesian estimation of phylogeny. To update Sequence Analysis mrbayes nml 1.0.2 mrbayes 3.2.7 (0/1) (0/1) (0/1) True True +mykrobe_parser mykrobe_parseR RScript to parse the results of mykrobe predictor. To update https://github.com/phac-nml/mykrobe-parser Sequence Analysis mykrobe_parser nml https://github.com/phac-nml/mykrobe-parser 0.1.4.1 r-base (0/1) (0/1) (0/1) True True +pangolin 7276.0 259.0 pangolin Phylogenetic Assignment of Named Global Outbreak LINeages To update https://github.com/hCoV-2019/pangolin Sequence Analysis pangolin nml https://github.com/hCoV-2019/pangolin 1.1.14 pangolin 4.3 (1/1) (1/1) (1/1) True False +patrist patrist Extract Patristic Distance From a Tree To update https://gist.github.com/ArtPoon/7330231e74201ded54b87142a1d6cd02 Phylogenetics patrist nml https://github.com/phac-nml/patrist 0.1.2 python (0/1) (0/1) (0/1) True False +plasmid_profiler_suite Plasmid Profiler suite defining all dependencies for Plasmid Profiler To update Sequence Analysis suite_plasmid_profiler nml (0/1) (0/1) (0/1) True False +plasmidspades plasmidspades Genome assembler for assemblying plasmid To update Assembly plasmidspades nml 1.1 spades 3.15.5 (0/1) (0/1) (0/1) True True +promer promer4_substitutions Aligns two sets of contigs and reports amino acid substitutions between them To update https://github.com/phac-nml/promer Assembly promer nml https://github.com/phac-nml/promer 1.2 python (0/1) (0/1) (0/1) True True +pseudogenome pseudogenome Create a pseudogenome from a multiple fasta file either with a JCVI linker or custom length and characters. To update https://github.com/phac-nml/galaxy_tools Sequence Analysis pseudogenome nml 1.0.0 perl-bioperl 1.7.8 (0/1) (0/1) (0/1) True False +quasitools aacoverage, aavariants, callcodonvar, callntvar, complexity_bam, complexity_fasta, consensus, distance, dnds, drmutations, hydra, quality A collection of tools for analysing Viral Quasispecies Up-to-date https://github.com/phac-nml/quasitools Sequence Analysis quasitools nml https://github.com/phac-nml/quasitools 0.7.0 quasitools 0.7.0 (0/12) (12/12) (0/12) True False +refseq_masher refseq_masher_contains, refseq_masher_matches Find what genomes match or are contained within your sequence data using Mash_ and a Mash sketch database. Up-to-date https://github.com/phac-nml/refseq_masher Sequence Analysis refseq_masher nml https://github.com/phac-nml/refseq_masher 0.1.2 refseq_masher 0.1.2 (0/2) (0/2) (0/2) True False +seqtk_nml seqtk_nml_sample Tool to downsample fastq reads To update https://github.com/lh3/seqtk Sequence Analysis seqtk_nml nml https://github.com/phac-nml/snvphyl-galaxy 1.0.1 seqtk 1.4 (0/1) (0/1) (0/1) True False +sistr_cmd 2489.0 133.0 sistr_cmd SISTR in silico serotyping tool Up-to-date https://github.com/phac-nml/sistr_cmd Sequence Analysis sistr_cmd nml 1.1.1 sistr_cmd 1.1.1 (0/1) (1/1) (1/1) True True +smalt smalt SMALT aligns DNA sequencing reads with a reference genome. Up-to-date http://www.sanger.ac.uk/science/tools/smalt-0 Sequence Analysis smalt nml https://sourceforge.net/projects/smalt/ 0.7.6 smalt 0.7.6 (0/1) (0/1) (0/1) True True +spatyper spatyper Determines SPA type based on repeats in a submitted staphylococcal protein A fasta file. Up-to-date https://github.com/HCGB-IGTP/spaTyper Sequence Analysis spatyper nml https://github.com/phac-nml/galaxy_tools/tree/master/tools/spatyper 0.3.3 spatyper 0.3.3 (0/1) (0/1) (0/1) True False +spolpred spolpred A program for predicting the spoligotype from raw sequence reads To update Sequence Analysis spolpred nml 1.0.1 spolpred (0/1) (0/1) (0/1) True False +srst2 205.0 22.0 srst2 Short Read Sequence Typing for Bacterial Pathogens To update Sequence Analysis srst2 nml 0.3.7 srst2 0.2.0 (0/1) (0/1) (1/1) True True +staramr 12673.0 889.0 staramr_search Scan genome contigs against the ResFinder, PlasmidFinder, and PointFinder antimicrobial resistance databases. Up-to-date https://github.com/phac-nml/staramr Sequence Analysis staramr nml https://github.com/phac-nml/galaxy_tools/tree/master/tools/staramr 0.10.0 staramr 0.10.0 (1/1) (1/1) (1/1) True True +stringmlst stringmlst Rapid and accurate identification of the sequence type (ST) To update Sequence Analysis stringmlst nml 1.1.0 stringMLST 0.6.3 (0/1) (0/1) (0/1) True True +wade wade identify regions of interest To update https://github.com/phac-nml/wade Sequence Analysis wade nml https://github.com/phac-nml/wade 0.2.5+galaxy1 wade 0.2.6 (0/1) (0/1) (0/1) True False +isoplot 2.0 1.0 isoplot Isoplot is a software for the visualisation of MS data from C13 labelling experiments To update Metabolomics, Visualization isoplot workflow4metabolomics https://github.com/llegregam/Isoplot/tree/main 1.3.0+galaxy1 isoplot 1.3.1 (0/1) (0/1) (1/1) True False +repeatexplorer2 repeatexplorer_clustering Tool for annotation of repeats from unassembled shotgun reads. To update https://github.com/repeatexplorer/repex_tarean Genome annotation repeatexplorer2 gga https://github.com/galaxy-genome-annotation/galaxy-tools/tree/master/tools/repeatexplorer2 2.3.8 (0/1) (0/1) (1/1) False +best_regression_subsets 3.0 BestSubsetsRegression1 Perform Best-subsets Regression To update Sequence Analysis, Variant Analysis best_regression_subsets devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/best_regression_subsets 1.0.0 numpy (1/1) (0/1) (1/1) True False +blat_coverage_report generate_coverage_report Polymorphism of the Reads To update Next Gen Mappers, Sequence Analysis blat_coverage_report devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/blat_coverage_report 1.0.0 (0/1) (0/1) (0/1) True False +blat_mapping blat2wig Coverage of the Reads in wiggle format To update Next Gen Mappers, Sequence Analysis blat_mapping devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/blat_mapping 1.0.0 (0/1) (0/1) (0/1) True False +cd_hit_dup cd_hit_dup simple tool for removing duplicates from sequencing reads To update Metagenomics, Sequence Analysis cd_hit_dup devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/cd_hit_dup 0.0.1 cd-hit-auxtools 4.8.1 (1/1) (0/1) (0/1) True True +compute_motif_frequencies_for_all_motifs 94.0 2.0 compute_motif_frequencies_for_all_motifs Compute Motif Frequencies For All Motifs, motif by motif. To update Sequence Analysis, Statistics compute_motif_frequencies_for_all_motifs devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/compute_motif_frequencies_for_all_motifs 1.0.0 (0/1) (1/1) (1/1) True False +compute_motifs_frequency 65.0 compute_motifs_frequency Compute Motif Frequencies in indel flanking regions. To update Sequence Analysis, Statistics compute_motifs_frequency devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/compute_motifs_frequency 1.0.0 (0/1) (1/1) (1/1) True False +count_gff_features 271.0 49.0 count_gff_features Count GFF Features To update Sequence Analysis count_gff_features devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/count_gff_features 0.2 galaxy-ops 1.1.0 (1/1) (1/1) (1/1) True False +ctd_batch 203.0 13.0 ctdBatch_1 CTD analysis of chemicals, diseases, or genes To update Sequence Analysis ctd_batch devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/ctd_batch 1.0.0 (0/1) (0/1) (1/1) True False +cummerbund 1782.0 31.0 cummeRbund Wrapper for the Bioconductor cummeRbund library To update https://bioconductor.org/packages/release/bioc/html/cummeRbund.html RNA, Visualization cummerbund devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/cummerbund 2.16.0 fonts-conda-ecosystem (1/1) (1/1) (1/1) True False +delete_overlapping_indels 39.0 2.0 delete_overlapping_indels Delete Overlapping Indels from a chromosome indels file To update Sequence Analysis delete_overlapping_indels devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/delete_overlapping_indels 1.0.0 (0/1) (0/1) (1/1) True False +divide_pg_snp 31.0 dividePgSnp Separate pgSnp alleles into columns To update Sequence Analysis divide_pg_snp devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/divide_pg_snp 1.0.0 (1/1) (0/1) (1/1) True False +express 325.0 12.0 express Quantify the abundances of a set of target sequences from sampled subsequences To update RNA express devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/express 1.1.1 eXpress 1.5.1 (0/1) (1/1) (1/1) True False +featurecounter 22384.0 6.0 featureCoverage1 Feature coverage To update Sequence Analysis, Variant Analysis featurecounter devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/featurecounter 2.0.0 bx-python 0.11.0 (1/1) (0/1) (1/1) True False +filter_transcripts_via_tracking 20.0 1.0 filter_combined_via_tracking Filter Combined Transcripts To update RNA filter_transcripts_via_tracking devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/filter_transcripts_via_tracking 0.1 (1/1) (1/1) (1/1) True False +generate_pc_lda_matrix 119.0 12.0 generate_matrix_for_pca_and_lda1 Generate a Matrix for using PC and LDA To update Sequence Analysis generate_pc_lda_matrix devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/generate_pc_lda_matrix 1.0.0 (1/1) (1/1) (1/1) True False +getindelrates_3way indelRates_3way Estimate Indel Rates for 3-way alignments To update Sequence Analysis, Variant Analysis getindelrates_3way devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/getindelrates_3way 1.0.0 bx-python 0.11.0 (1/1) (0/1) (0/1) True False +getindels_2way getIndels_2way Fetch Indels from pairwise alignments To update Sequence Analysis, Variant Analysis getindels_2way devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/getindels_2way 1.0.0 numpy (1/1) (0/1) (0/1) True False +gmaj 11.0 4.0 gmaj_1 GMAJ Multiple Alignment Viewer To update Visualization gmaj devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/gmaj 2.0.1 (1/1) (1/1) (1/1) True False +hisat 228.0 hisat HISAT is a fast and sensitive spliced alignment program. To update http://ccb.jhu.edu/software/hisat/index.shtml Assembly hisat devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/hisat 1.0.3 hisat (0/1) (0/1) (0/1) True False +indels_3way 22.0 indels_3way Fetch Indels from 3-way alignments To update Sequence Analysis indels_3way devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/indels_3way 1.0.3 (1/1) (0/1) (1/1) True False +logistic_regression_vif LogisticRegression Perform Logistic Regression with vif To update Sequence Analysis, Variant Analysis, Statistics logistic_regression_vif devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/logistic_regression_vif 1.0.1 numpy (0/1) (0/1) (0/1) True False +maf_cpg_filter cpgFilter Mask CpG/non-CpG sites from MAF file To update Sequence Analysis, Variant Analysis maf_cpg_filter devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/maf_cpg_filter 1.0.0 bx-python 0.11.0 (1/1) (0/1) (0/1) True False +mapping_to_ucsc mapToUCSC Format mapping data as UCSC custom track To update Visualization, Convert Formats, Next Gen Mappers mapping_to_ucsc devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/mapping_to_ucsc 1.0.0 (0/1) (0/1) (0/1) True False +microsatellite_birthdeath microsatellite_birthdeath Identify microsatellite births and deaths To update Sequence Analysis microsatellite_birthdeath devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/microsatellite_birthdeath 1.0.0 (0/1) (0/1) (0/1) True False +microsats_alignment_level microsats_align1 Extract Orthologous Microsatellites from pair-wise alignments To update Sequence Analysis, Variant Analysis microsats_alignment_level devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/microsats_alignment_level 1.0.0 sputnik (1/1) (0/1) (0/1) True False +microsats_mutability microsats_mutability1 Estimate microsatellite mutability by specified attributes To update Sequence Analysis, Variant Analysis microsats_mutability devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/microsats_mutability 1.1.0 bx-python 0.11.0 (1/1) (0/1) (0/1) True False +multispecies_orthologous_microsats multispecies_orthologous_microsats Extract orthologous microsatellites To update Sequence Analysis, Variant Analysis multispecies_orthologous_microsats devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/multispecies_orthologous_microsats 1.0.0 bx-sputnik (0/1) (0/1) (0/1) True True +quality_filter qualityFilter Filter nucleotides based on quality scores To update Sequence Analysis, Variant Analysis quality_filter devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/quality_filter 1.0.1 bx-python 0.11.0 (0/1) (0/1) (0/1) True True +rcve rcve1 Compute RCVE To update Sequence Analysis, Variant Analysis rcve devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/rcve 1.0.0 R (1/1) (0/1) (0/1) True False +short_reads_figure_high_quality_length hist_high_quality_score Histogram of high quality score reads To update Sequence Analysis, Graphics short_reads_figure_high_quality_length devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/short_reads_figure_high_quality_length 1.0.0 rpy (0/1) (0/1) (0/1) True False +short_reads_figure_score 163.0 13.0 quality_score_distribution Build base quality distribution To update Sequence Analysis, Graphics short_reads_figure_score devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/short_reads_figure_score 1.0.2 fontconfig (0/1) (0/1) (1/1) True False +substitution_rates subRate1 Estimate substitution rates for non-coding regions To update Sequence Analysis, Variant Analysis substitution_rates devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/substitution_rates 1.0.0 (0/1) (0/1) (0/1) True False +substitutions substitutions1 Fetch substitutions from pairwise alignments To update Sequence Analysis, Variant Analysis substitutions devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/substitutions 1.0.1 bx-python 0.11.0 (1/1) (0/1) (0/1) True False +tophat 1.0 tophat Tophat for Illumina To update RNA, Next Gen Mappers tophat devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/tophat 1.5.0 samtools 1.19.2 (0/1) (0/1) (0/1) True False +tophat2 24167.0 312.0 tophat2 Tophat - fast splice junction mapper for RNA-Seq reads To update http://ccb.jhu.edu/software/tophat/index.shtml RNA, Next Gen Mappers tophat2 devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/tophat2 2.1.1 bowtie2 2.5.3 (1/1) (1/1) (1/1) True False +ucsc_custom_track 393.0 45.0 build_ucsc_custom_track_1 Build custom track for UCSC genome browser To update Sequence Analysis ucsc_custom_track devteam https://github.com/galaxyproject/tools-devteam/tree/main/tools/ucsc_custom_track 1.0.1 python (1/1) (0/1) (1/1) True False +weightedaverage wtavg Assign weighted-average of the values of features overlapping an interval To update Sequence Analysis, Variant Analysis weightedaverage devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/weightedaverage 1.0.1 galaxy-ops 1.1.0 (1/1) (0/1) (0/1) True False +windowsplitter winSplitter Make windows To update Sequence Analysis, Variant Analysis windowsplitter devteam https://github.com/galaxyproject/tools-devteam/tree/master/tools/windowsplitter 1.0.1 bx-python 0.11.0 (1/1) (0/1) (0/1) True False +hgv_fundo hgv_funDo FunDO human genes associated with disease terms To update Sequence Analysis hgv_fundo devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/hgv/hgv_fundo 1.0.0 (1/1) (0/1) (1/1) True False +hgv_hilbertvis hgv_hilbertvis HVIS visualization of genomic data with the Hilbert curve To update https://www.ebi.ac.uk/huber-srv/hilbert/ Graphics, Visualization hgv_hilbertvis devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/hgv/hgv_hilbertvis 1.0.0 R (1/1) (0/1) (1/1) True False +find_diag_hits 69.0 5.0 find_diag_hits Find diagnostic hits To update https://bitbucket.org/natefoo/taxonomy Metagenomics find_diag_hits devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/find_diag_hits 1.0.0 taxonomy 0.10.0 (0/1) (0/1) (1/1) True False +gi2taxonomy 660.0 27.0 Fetch Taxonomic Ranks Fetch taxonomic representation To update https://bitbucket.org/natefoo/taxonomy Metagenomics gi2taxonomy devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/gi2taxonomy 1.1.1 taxonomy 0.10.0 (0/1) (0/1) (1/1) True True +kraken2tax 14683.0 481.0 Kraken2Tax Convert Kraken output to Galaxy taxonomy data. To update https://bitbucket.org/natefoo/taxonomy Metagenomics kraken2tax devteam https://github.com/galaxyproject/tools-devteam/blob/master/tool_collections/taxonomy/kraken2tax/ 1.2+galaxy0 gawk (1/1) (1/1) (1/1) True True +lca_wrapper 137.0 2.0 lca1 Find lowest diagnostic rank To update https://bitbucket.org/natefoo/taxonomy Metagenomics lca_wrapper devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/lca_wrapper 1.0.1 taxonomy 0.10.0 (0/1) (0/1) (1/1) True True +poisson2test 116.0 6.0 poisson2test Poisson two-sample test To update https://bitbucket.org/natefoo/taxonomy Statistics, Metagenomics poisson2test devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/poisson2test 1.0.0 taxonomy 0.10.0 (0/1) (1/1) (1/1) True False +t2ps 457.0 31.0 Draw_phylogram Draw phylogeny To update https://bitbucket.org/natefoo/taxonomy Metagenomics t2ps devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/t2ps 1.0.0 taxonomy 0.10.0 (0/1) (0/1) (1/1) True True +t2t_report 947.0 26.0 t2t_report Summarize taxonomy To update https://bitbucket.org/natefoo/taxonomy Metagenomics t2t_report devteam https://github.com/galaxyproject/tools-devteam/tree/master/tool_collections/taxonomy/t2t_report 1.0.0 taxonomy 0.10.0 (0/1) (0/1) (1/1) True True +AggregateAlignments graphclust_aggregate_alignments Aggregate and filter alignment metrics of individual clusters, like the output of graphclust_align_cluster. Up-to-date RNA graphclust_aggregate_alignments rnateam https://github.com/bgruening/galaxytools/tools/GraphClust/AggregateAlignments 0.6.0 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +AlignCluster graphclust_align_cluster Align predicted clusters of glob_report_no_align step with locarna and conservation analysis and visualizations. To update RNA graphclust_align_cluster rnateam https://github.com/bgruening/galaxytools/tools/GraphClust/AlignCluster 0.1 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +CMFinder cmFinder Determines consensus motives for sequences. To update RNA graphclust_cmfinder rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/CMFinder 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +CollectResults glob_report Post-processing. Redundant clusters are merged and instances that belong to multiple clusters are assigned unambiguously. For every pair of clusters, the relative overlap (i.e. the fraction of instances that occur in both clusters) is computed and clusters are merged if the overlap exceeds 50%. instances that occur in both clusters) is computed and clusters are merged if the overlap exceeds 50%. To update RNA graphclust_postprocessing rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/CollectResults 0.5 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +CollectResultsNoAlign graphclust_glob_report_no_align Redundant GraphClust clusters are merged and instances that belong to multiple clusters are assigned unambiguously. To update RNA graphclust_postprocessing_no_align rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/CollectResultsNoAlign 0.5 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +GSPAN gspan Second step of GraphClust To update RNA graphclust_fasta_to_gspan rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/GSPAN 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +LocARNAGraphClust locarna_best_subtree MLocARNA computes a multiple sequence-structure alignment of RNA sequences. To update RNA graphclust_mlocarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/LocARNAGraphClust 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +NSPDK NSPDK_candidateClust, nspdk_sparse Produces an explicit sparse feature encoding and copmutes global feature index and returns top dense sets. To update RNA graphclust_nspdk rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/NSPDK 9.2.3.1 graphclust-wrappers 0.6.0 (0/2) (0/2) (2/2) True False +Plotting motifFinderPlot Plotting results for GraphClust To update RNA graphclust_motif_finder_plot rnateam https://github.com/eteriSokhoyan/galaxytools/tree/master/tools/GraphClust/Plotting 0.4 seaborn (0/1) (0/1) (1/1) True False +PrepareForMlocarna preMloc This tool prepares files for locarna step. To update RNA graphclust_prepocessing_for_mlocarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust/PrepareForMlocarna 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +Preprocessing preproc Preprocessing input for GraphClust To update RNA graphclust_preprocessing rnateam https://github.com/bgruening/galaxytools/tree/master/tools/GraphClust 0.5 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +Structure_GSPAN structure_to_gspan Convert RNA structure to GSPAN graphs To update RNA structure_to_gspan rnateam https://github.com/mmiladi/galaxytools/blob/graphclust-gspan/tools/GraphClust/Structure_GSPAN 0.4 graphclust-wrappers 0.6.0 (0/1) (0/1) (1/1) True False +antismash 14596.0 279.0 antismash Antismash allows the genome-wide identification, annotation and analysis of secondary metabolite biosynthesis gene clusters antismash antiSMASH Rapid genome-wide identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genomes. It integrates and cross-links with a large number of in silico secondary metabolite analysis tools that have been published earlier. Sequence clustering, Gene prediction, Differential gene expression analysis Molecular interactions, pathways and networks, Gene and protein families To update https://antismash.secondarymetabolites.org Sequence Analysis antismash bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/antismash 6.1.1 antismash 7.1.0 (1/1) (1/1) (1/1) True True +augustus 8864.0 516.0 augustus AUGUSTUS is a program that predicts genes in eukaryotic genomic sequences. To update http://bioinf.uni-greifswald.de/augustus/ Sequence Analysis augustus bgruening https://github.com/bgruening/galaxytools/tree/master/tools/augustus 3.1.0 augustus 3.5.0 (1/1) (1/1) (1/1) True False +bamhash 169.0 15.0 bamhash Hash BAM and FASTQ files to verify data integrity Up-to-date https://github.com/DecodeGenetics/BamHash Sequence Analysis bamhash bgruening https://github.com/bgruening/galaxytools/tree/master/tools/bamhash 1.1 bamhash 1.1 (0/1) (0/1) (1/1) True False +barcode_collapse barcode_collapse Paired End randomer aware duplicate removal algorithm To update https://github.com/YeoLab/gscripts RNA, Sequence Analysis barcode_collapse rnateam https://github.com/bgruening/galaxytools/tree/master/tools/barcode_collapse 0.1.0 pysam 0.22.0 (0/1) (0/1) (0/1) True False +bionano bionano_scaffold Bionano Solve is a set of tools for analyzing Bionano data To update https://bionanogenomics.com/ Assembly bionano bgruening https://github.com/bgruening/galaxytools/tree/master/tools/bionano 3.7.0 (1/1) (1/1) (1/1) True False +bismark 13575.0 404.0 bismark_pretty_report, bismark_bowtie2, bismark_deduplicate, bismark_methylation_extractor A tool to map bisulfite converted sequence reads and determine cytosine methylation states To update https://www.bioinformatics.babraham.ac.uk/projects/bismark/ Sequence Analysis, Next Gen Mappers bismark bgruening https://github.com/bgruening/galaxytools/tree/master/tools/bismark 0.22.1 bismark 0.24.2 (0/4) (0/4) (4/4) True False +blobtoolkit 685.0 21.0 blobtoolkit Identification and isolation non-target data in draft and publicly available genome assemblies. To update https://blobtoolkit.genomehubs.org/ Sequence Analysis, Assembly blobtoolkit bgruening https://github.com/bgruening/galaxytools/tree/master/tools/blobtoolkit 4.0.7 (0/1) (1/1) (1/1) True False +blockbuster 3009.0 34.0 blockbuster Blockbuster detects blocks of overlapping reads using a gaussian-distribution approach. To update http://hoffmann.bioinf.uni-leipzig.de/LIFE/blockbuster.html RNA, Sequence Analysis blockbuster rnateam https://github.com/bgruening/galaxytools/tree/master/tools/blockbuster 0.1.2 blockbuster 0.0.1.1 (1/1) (1/1) (1/1) True False +chipseeker 15690.0 418.0 chipseeker A tool for ChIP peak annotation and visualization To update https://bioconductor.org/packages/release/bioc/html/ChIPseeker.html ChIP-seq, Genome annotation chipseeker rnateam https://github.com/bgruening/galaxytools/tree/master/tools/chipseeker 1.32.0 bioconductor-chipseeker 1.38.0 (1/1) (1/1) (1/1) True False +circexplorer 251.0 8.0 circexplorer A combined strategy to identify circular RNAs (circRNAs and ciRNAs) To update https://github.com/YangLab/CIRCexplorer Sequence Analysis, RNA circexplorer bgruening https://github.com/bgruening/galaxytools/tree/master/tools/circexplorer 1.1.9.0 circexplorer 1.1.10 (0/1) (1/1) (1/1) True False +combine_metaphlan_humann combine_metaphlan_humann Combine MetaPhlAn2 and HUMAnN2 outputs to relate genus/species abundances and gene families/pathways abundances combine_metaphlan_and_humann Combine Metaphlan and HUMAnN """This tool combine MetaPhlAn outputs and HUMANnN outputs."" - Galaxy tool wrapper" Aggregation Metagenomics, Molecular interactions, pathways and networks To update Metagenomics combine_metaphlan2_humann2 bebatut https://github.com/bgruening/galaxytools/tree/master/tools/combine_metaphlan2_humann2 0.3.0 python (0/1) (0/1) (1/1) True True +compare_humann2_output 332.0 10.0 compare_humann2_output Compare outputs of HUMAnN2 for several samples and extract similar and specific information compare_humann2_outputs Compare HUMAnN2 outputs """This tool compare HUMANnN2 outputs with gene families or pathways and their relative abundances between several samples."" - Galaxy tool wrapper" Comparison Metagenomics, Gene and protein families To update Metagenomics compare_humann2_output bebatut https://github.com/bgruening/galaxytools/tree/master/tools/compare_humann2_output 0.2.0 (0/1) (0/1) (0/1) True True +crt crispr_recognition_tool CRISPR Recognition Tool To update Sequence Analysis crispr_recognition_tool bgruening https://github.com/bgruening/galaxytools/tree/master/tools/crt 1.2.0 crisper_recognition_tool 1.2 (0/1) (0/1) (1/1) True False +flye 20904.0 1499.0 flye Assembly of long and error-prone reads. To update https://github.com/fenderglass/Flye/ Assembly flye bgruening https://github.com/bgruening/galaxytools/tree/master/tools/flye 2.9.1 flye 2.9.3 (1/1) (1/1) (1/1) True True +format_metaphlan2_output 5588.0 166.0 format_metaphlan2_output Format MetaPhlAn2 output to extract abundance at different taxonomic levels format_metaphlan2_output Format metaphlan2 output """This tool format output file of MetaPhlan2 containing community content (abundance) at all taxonomic levels (from kingdom to strains)."" - Galaxy tool wrapper" Formatting Taxonomy, Metagenomics To update Metagenomics format_metaphlan2_output bebatut https://github.com/bgruening/galaxytools/tree/master/tools/format_metaphlan2_output/ 0.2.0 (0/1) (0/1) (1/1) True True +gfastats 8159.0 418.0 gfastats Tool for generating sequence statistics and simultaneous genome assembly file manipulation. gfastats gfastats gfastats is a single fast and exhaustive tool for summary statistics and simultaneous genome assembly file manipulation. gfastats also allows seamless fasta/fastq/gfa conversion. Data handling Computational biology Up-to-date https://github.com/vgl-hub/gfastats Sequence Analysis gfastats bgruening https://github.com/bgruening/galaxytools/tree/master/tools/gfastats 1.3.6 gfastats 1.3.6 (1/1) (1/1) (1/1) True False +glimmer_hmm GlimmerHMM is a new gene finder based on a Generalized Hidden Markov Model (GHMM) To update https://ccb.jhu.edu/software/glimmerhmm/ Sequence Analysis glimmer_hmm bgruening https://github.com/bgruening/galaxytools/tree/master/tools/glimmer_hmm (0/1) (0/1) (0/1) True True +gotohscan 71.0 1.0 rbc_gotohscan Find subsequences in db To update Sequence Analysis gotohscan rnateam https://github.com/bgruening/galaxytools/tree/master/tools/gotohscan 1.3.0 gotohscan 1.3 (0/1) (0/1) (1/1) True False +graphclust 6.0 graphclust GraphClust can be used for structural clustering of RNA sequences. To update http://www.bioinf.uni-freiburg.de/Software/GraphClust/ RNA graphclust bgruening https://github.com/bgruening/galaxytools/tree/master/tools/graphclust 0.1 GraphClust (0/1) (0/1) (0/1) True False +graphmap graphmap_align, graphmap_overlap Mapper for long, error-prone reads. To update https://github.com/isovic/graphmap/ Assembly graphmap bgruening https://github.com/bgruening/galaxytools/tree/master/tools/graphmap 0.5.2 graphmap 0.6.3 (0/2) (0/2) (2/2) True True +hifiasm 1410.0 297.0 hifiasm A fast haplotype-resolved de novo assembler Up-to-date https://github.com/chhylp123/hifiasm Assembly hifiasm bgruening https://github.com/bgruening/galaxytools/tree/master/tools/hifiasm 0.19.8 hifiasm 0.19.8 (1/1) (1/1) (1/1) True False +homer Software for motif discovery and next generation sequencing analysis. To update http://homer.salk.edu/homer/ Sequence Analysis homer bgruening https://github.com/bgruening/galaxytools/tree/master/tools/homer (0/1) (0/1) (0/1) True False +illumina_methylation_analyser illumina_methylation_analyser Methylation analyzer for Illumina 450k DNA emthylation microarrays To update https://github.com/bgruening/galaxytools/tree/master/tools/illumina_methylation_analyser Sequence Analysis illumina_methylation_analyser bgruening https://github.com/bgruening/galaxytools/tree/master/tools/illumina_methylation_analyser 0.1 Rscript (0/1) (0/1) (0/1) True False +instagraal 139.0 14.0 instagraal Large genome reassembly based on Hi-C data instagraal instaGRAAL Chromosome-level quality scaffolding of brown algal genomes using InstaGRAAL.Large genome reassembly based on Hi-C data, continuation of GRAAL.Large genome reassembly based on Hi-C data (continuation and partial rewrite of GRAAL) and post-scaffolding polishing libraries.This work is under continuous development/improvement - see GRAAL for information about the basic principles.sudo pip3 install -e git+https://github.com/koszullab/instagraal.git@master#egg=instagraal.Note to OS X users: There is currently no CUDA support on Mojave (10.14) and it is unclear when it is going to be added, if it is to be added at all. This means instaGRAAL (or indeed any CUDA-based application) will not work on Mojave. If you wish to run it on OS X, the only solution for now is to downgrade to High Sierra (10.13) Genome assembly, Mapping assembly, Genetic mapping, Scaffolding Sequence assembly, Mapping, Metagenomics, Statistics and probability, DNA binding sites To update https://github.com/koszullab/instaGRAAL Assembly instagraal bgruening https://github.com/bgruening/galaxytools/tree/master/tools/instagraal 0.1.6 (0/1) (0/1) (1/1) True False +iprscan5 Interproscan queries the interpro database and provides annotations. To update http://www.ebi.ac.uk/Tools/pfa/iprscan5/ Sequence Analysis iprscan5 bgruening https://github.com/bgruening/galaxytools/tree/master/tools/iprscan5 (0/1) (0/1) (0/1) True True +itsx 868.0 38.0 itsx ITSx is an open source software utility to extract the highly variable ITS1 and ITS2 subregions from ITS sequences. ITSx ITSx TSx is an open source software utility to extract the highly variable ITS1 and ITS2 subregions from ITS sequences, which is commonly used as a molecular barcode for e.g. fungi. As the inclusion of parts of the neighbouring, very conserved, ribosomal genes (SSU, 5S and LSU rRNA sequences) in the sequence identification process can lead to severely misleading results, ITSx identifies and extracts only the ITS regions themselves. Sequence feature detection Functional, regulatory and non-coding RNA, Microbiology Up-to-date https://microbiology.se/software/itsx/ Metagenomics itsx bgruening https://github.com/bgruening/galaxytools/tree/master/tools/itsx 1.1.3 itsx 1.1.3 (0/1) (0/1) (1/1) True True +labels bg_labels remaps and annotates alignments To update https://github.com/bgruening/galaxytools/tree/master/tools/labels Sequence Analysis labels bgruening https://github.com/bgruening/galaxytools/tree/master/tools/labels 1.0.5.0 labels (0/1) (0/1) (0/1) True False +lighter 152.0 9.0 lighter Lighter is a kmer-based error correction method for whole genome sequencing data To update Sequence Analysis, Fasta Manipulation lighter bgruening https://github.com/mourisl/Lighter 1.0 lighter 1.1.2 (0/1) (0/1) (1/1) True True +mafft 143045.0 817.0 rbc_mafft_add, rbc_mafft Multiple alignment program for amino acid or nucleotide sequences MAFFT MAFFT MAFFT (Multiple Alignment using Fast Fourier Transform) is a high speed multiple sequence alignment program. Multiple sequence alignment Sequence analysis To update RNA mafft rnateam https://github.com/bgruening/galaxytools/tree/master/tools/mafft 7.508 mafft 7.520 (2/2) (2/2) (2/2) True True +mcl 29.0 10.0 mcl_clustering Markov Cluster Algorithm To update http://micans.org/mcl/ Sequence Analysis, Metagenomics mcl bgruening https://github.com/bgruening/galaxytools/tree/master/tools/mcl 14.137 mcl 22.282 (0/1) (0/1) (0/1) True True +methtools methtools_calling, r_correlation_matrix, methtools_destrand, methtools_dmr, methtools_filter, methtools_plot, smooth_running_window, methtools_tiling tools for methylation analysis To update https://github.com/bgruening/galaxytools/tree/master/tools/methtools Sequence Analysis methtools bgruening https://github.com/bgruening/galaxytools/tree/master/tools/methtools 0.1.1 methtools (0/8) (0/8) (0/8) True False +methyldackel pileometh A tool for processing bisulfite sequencing alignments To update https://github.com/dpryan79/MethylDackel Sequence Analysis pileometh bgruening https://github.com/bgruening/galaxytools/tree/master/tools/methyldackel 0.5.2 methyldackel 0.6.1 (1/1) (1/1) (1/1) True False +metilene 3966.0 103.0 metilene Differential DNA methylation calling To update RNA, Statistics metilene rnateam https://github.com/bgruening/galaxytools/tree/master/tools/metilene 0.2.6.1 metilene 0.2.8 (1/1) (1/1) (1/1) True False +miclip mi_clip Identification of binding sites in CLIP-Seq data. To update https://cran.r-project.org/src/contrib/Archive/MiClip/ Sequence Analysis miclip bgruening https://github.com/bgruening/galaxytools/tree/master/tools/miclip 1.2.0 Rscript (0/1) (0/1) (0/1) True False +minced 895.0 53.0 minced MinCED - Mining CRISPRs in Environmental Datasets To update http://bioweb2.pasteur.fr/docs/modules/minced/0.1.5/_README Sequence Analysis minced bgruening https://github.com/bgruening/galaxytools/tree/master/tools/minced 0.2.0 minced 0.4.2 (0/1) (0/1) (1/1) True False +minipolish 185.0 21.0 minipolish Polishing miniasm assemblies minipolish minipolish A tool that bridges the output of miniasm (long-read assembly) and racon (assembly polishing) together to polish a draft assembly. It also provides read depth information in contigs. Localised reassembly, Read depth analysis Sequence assembly, Sequencing Up-to-date https://github.com/rrwick/Minipolish Sequence Analysis minipolish bgruening https://github.com/bgruening/galaxytools/tree/master/tools/minipolish 0.1.3 minipolish 0.1.3 (0/1) (0/1) (1/1) True True +mitohifi 613.0 56.0 mitohifi Assembly mitogenomes from Pacbio HiFi read. To update https://github.com/marcelauliano/MitoHiFi/tree/mitohifi_v2 Assembly mitohifi bgruening https://github.com/bgruening/galaxytools/tree/master/tools/mitohifi 3 (1/1) (1/1) (1/1) True False +nextdenovo 268.0 84.0 nextdenovo String graph-based de novo assembler for long reads nextdenovo NextDenovo "NextDenovo is a string graph-based de novo assembler for long reads (CLR, HiFi and ONT). It uses a ""correct-then-assemble"" strategy similar to canu (no correction step for PacBio Hifi reads), but requires significantly less computing resources and storages." De-novo assembly, Genome assembly Sequencing, Sequence assembly To update https://github.com/Nextomics/NextDenovo Assembly nextdenovo bgruening https://github.com/bgruening/galaxytools/tree/master/tools/nextdenovo 2.5.0 nextdenovo 2.5.2 (0/1) (0/1) (1/1) True True +nucleosome_prediction 861.0 2.0 Nucleosome Prediction of Nucleosomes Positions on the Genome Up-to-date https://genie.weizmann.ac.il/software/nucleo_exe.html Sequence Analysis nucleosome_prediction bgruening https://github.com/bgruening/galaxytools/tree/master/tools/nucleosome_prediction 3.0 nucleosome_prediction 3.0 (0/1) (0/1) (1/1) True True +openms AccurateMassSearch, AdditiveSeries, BaselineFilter, CVInspector, CompNovo, CompNovoCID, ConsensusID, ConsensusMapNormalizer, ConvertTSVToTraML, ConvertTraMLToTSV, DTAExtractor, DeMeanderize, Decharger, DecoyDatabase, Digestor, DigestorMotif, EICExtractor, ERPairFinder, ExternalCalibration, FFEval, FalseDiscoveryRate, FeatureFinderCentroided, FeatureFinderIdentification, FeatureFinderIsotopeWavelet, FeatureFinderMRM, FeatureFinderMetabo, FeatureFinderMultiplex, FeatureFinderSuperHirn, FeatureLinkerLabeled, FeatureLinkerUnlabeled, FeatureLinkerUnlabeledQT, FidoAdapter, FileConverter, FileFilter, FileInfo, FileMerger, FuzzyDiff, HighResPrecursorMassCorrector, IDConflictResolver, IDDecoyProbability, IDExtractor, IDFileConverter, IDFilter, IDMapper, IDMassAccuracy, IDMerger, IDPosteriorErrorProbability, IDRTCalibration, IDRipper, IDScoreSwitcher, IDSplitter, ITRAQAnalyzer, InclusionExclusionListCreator, InspectAdapter, InternalCalibration, IsobaricAnalyzer, LabeledEval, LowMemPeakPickerHiRes, LowMemPeakPickerHiRes_RandomAccess, LuciphorAdapter, MRMMapper, MRMPairFinder, MRMTransitionGroupPicker, MSGFPlusAdapter, MSSimulator, MapAlignmentEvaluation, MapNormalizer, MapRTTransformer, MapStatistics, MascotAdapter, MascotAdapterOnline, MassCalculator, MassTraceExtractor, MetaProSIP, MetaboliteSpectralMatcher, MultiplexResolver, MzMLSplitter, MzTabExporter, NoiseFilterGaussian, NoiseFilterSGolay, OpenSwathAnalyzer, OpenSwathAssayGenerator, OpenSwathChromatogramExtractor, OpenSwathConfidenceScoring, OpenSwathDIAPreScoring, OpenSwathDecoyGenerator, OpenSwathFeatureXMLToTSV, OpenSwathFileSplitter, OpenSwathMzMLFileCacher, OpenSwathRTNormalizer, OpenSwathRewriteToFeatureXML, OpenSwathWorkflow, PTModel, PTPredict, PeakPickerHiRes, PeakPickerIterative, PeakPickerWavelet, PepNovoAdapter, PeptideIndexer, PhosphoScoring, PrecursorIonSelector, PrecursorMassCorrector, ProteinInference, ProteinQuantifier, ProteinResolver, QCCalculator, QCEmbedder, QCExporter, QCExtractor, QCImporter, QCMerger, QCShrinker, RNPxl, RNPxlXICFilter, RTEvaluation, RTModel, RTPredict, SemanticValidator, SequenceCoverageCalculator, SimpleSearchEngine, SpecLibCreator, SpectraFilterBernNorm, SpectraFilterMarkerMower, SpectraFilterNLargest, SpectraFilterNormalizer, SpectraFilterParentPeakMower, SpectraFilterScaler, SpectraFilterSqrtMower, SpectraFilterThresholdMower, SpectraFilterWindowMower, SpectraMerger, SvmTheoreticalSpectrumGeneratorTrainer, TICCalculator, TMTAnalyzer, TOFCalibration, TextExporter, TopPerc, TransformationEvaluation, XMLValidator, XTandemAdapter OpenMS in version 2.1. To update Proteomics openms bgruening https://github.com/bgruening/galaxytools/tree/master/tools/openms 2.1.0 openms 3.1.0 (0/140) (34/140) (135/140) True False +peakachu 3109.0 78.0 peakachu PEAKachu is a peak-caller for CLIP- and RIP-Seq data To update Sequence Analysis, RNA peakachu rnateam https://github.com/tbischler/PEAKachu 0.2.0+galaxy1 peakachu 0.2.0 (0/1) (0/1) (1/1) True False +pfamscan 165.0 19.0 pfamscan Search a FASTA sequence against a library of Pfam HMM. pfamscan PfamScan This tool is used to search a FASTA sequence against a library of Pfam HMM. Protein sequence analysis Sequence analysis Up-to-date http://ftp.ebi.ac.uk/pub/databases/Pfam/Tools/ Sequence Analysis pfamscan bgruening https://github.com/bgruening/galaxytools/tree/master/tools/pfamscan 1.6 pfam_scan 1.6 (1/1) (1/1) (1/1) True True +piranha 1809.0 39.0 piranha Piranha is a peak-caller for CLIP- and RIP-Seq data To update Sequence Analysis, RNA piranha rnateam https://github.com/galaxyproject/tools-iuc/tree/master/tools/piranha 1.2.1.0 piranha 1.2.1 (0/1) (0/1) (1/1) True False +platypus bg_platypus efficient and accurate variant-detection in high-throughput sequencing data To update http://www.well.ox.ac.uk/platypus Sequence Analysis platypus bgruening https://github.com/bgruening/galaxytools/tree/master/tools/platypus 0.0.11 platypus (0/1) (0/1) (0/1) True False +plotly_ml_performance_plots 1323.0 71.0 plotly_ml_performance_plots performance plots for machine learning problems To update http://scikit-learn.org/stable/modules/classes.html#module-sklearn.metrics Visualization plotly_ml_performance_plots bgruening https://github.com/bgruening/galaxytools/tree/master/tools/plotly_ml_performance_plots 0.2 pandas (1/1) (1/1) (1/1) True False +plotly_parallel_coordinates_plot 652.0 37.0 plotly_parallel_coordinates_plot parallel coordinates plot produced with plotly To update https://plot.ly/python/parallel-coordinates-plot/ Visualization plotly_parallel_coordinates_plot bgruening https://github.com/bgruening/galaxytools/tree/master/tools/plotly_parallel_coordinates_plot 0.2 python (1/1) (1/1) (1/1) True False +plotly_regression_performance_plots 843.0 79.0 plotly_regression_performance_plots performance plots for regression problems To update http://scikit-learn.org/stable/supervised_learning.html#supervised-learning Visualization plotly_regression_performance_plots bgruening https://github.com/bgruening/galaxytools/tree/master/tools/plotly_regression_performance_plots 0.1 python (1/1) (1/1) (1/1) True False +protease_prediction 149.0 4.0 eden_protease_prediction This tool can learn the cleavage specificity of a given class of proteases. To update https://github.com/fabriziocosta/eden Sequence Analysis, Proteomics protease_prediction bgruening https://github.com/bgruening/galaxytools/tree/master/tools/protease_prediction 0.9 eden 2.0 (0/1) (0/1) (1/1) True False +protein_properties 256.0 15.0 bg_protein_properties Calculation of various properties from given protein sequences To update Sequence Analysis protein_properties bgruening https://github.com/bgruening/galaxytools/tree/master/tools/protein_properties 0.2.0 biopython 1.70 (0/1) (0/1) (1/1) True False +improviser proteomics_improviser Visualisation of PepXML files To update http://www.improviser.uni-freiburg.de/ Proteomics proteomics_improviser bgruening https://github.com/bgruening/galaxytools/tree/master/tools/proteomics/improviser 1.1.0.1 (0/1) (0/1) (0/1) True False +racon 21353.0 309.0 racon Consensus module for raw de novo DNA assembly of long uncorrected reads. Racon Racon The Possibility to Use Oxford Nanopore Technology | Ultrafast consensus module for raw de novo genome assembly of long uncorrected reads. http://genome.cshlp.org/content/early/2017/01/18/gr.214270.116 Note: This was the original repository which will no longer be officially maintained. Please use the new official repository here: https://github.com/isovic/racon| Racon is intended as a standalone consensus module to correct raw contigs generated by rapid assembly methods which do not include a consensus step | Consensus module for raw de novo DNA assembly of long uncorrected reads Genome assembly, Mapping assembly, Sequence trimming Whole genome sequencing, Sequence assembly, Plant biology Up-to-date https://github.com/isovic/racon Sequence Analysis racon bgruening https://github.com/bgruening/galaxytools/tree/master/tools/racon 1.5.0 racon 1.5.0 (1/1) (1/1) (1/1) True True +repeat_masker 3750.0 248.0 repeatmasker_wrapper RepeatMasker is a program that screens DNA sequences for interspersed repeats and low complexity DNA sequences. To update http://www.repeatmasker.org/ Sequence Analysis repeat_masker bgruening https://github.com/bgruening/galaxytools/tree/master/tools/repeat_masker 0.1.2 RepeatMasker 4.1.5 (1/1) (1/1) (1/1) True False +antarna 52.0 2.0 antarna antaRNA uses ant colony optimization to solve the inverse folding problem in RNA research . To update RNA antarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/antarna/ 1.1 antarna 2.0.1.2 (0/1) (0/1) (1/1) True False +aresite2 65.0 4.0 AREsite2_REST AREsite2 REST Interface To update http://rna.tbi.univie.ac.at/AREsite RNA, Data Source, Sequence Analysis aresite2 rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/aresite2 0.1.2 python (0/1) (0/1) (1/1) True False +blockclust 1478.0 15.0 blockclust BlockClust detects transcripts with similar processing patterns. Up-to-date https://github.com/bgruening/galaxytools/tree/master/workflows/blockclust RNA blockclust rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/blockclust 1.1.1 blockclust 1.1.1 (1/1) (1/1) (1/1) True False +cmsearch_deoverlap 102.0 1.0 cmsearch_deoverlap removes lower scoring overlaps from cmsearch results. To update https://github.com/EBI-Metagenomics/pipeline-v5/blob/master/tools/RNA_prediction/cmsearch-deoverlap/cmsearch-deoverlap.pl RNA cmsearch_deoverlap rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/cmsearch_deoverlap 0.08+galaxy0 perl (0/1) (0/1) (1/1) True False +cmv 70.0 1.0 cmcv, cmv, hmmcv, hmmv cmv is a collection of tools for the visualisation of Hidden Markov Models and RNA-family models. Up-to-date https://github.com/eggzilla/cmv RNA cmv rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/cmv 1.0.8 cmv 1.0.8 (0/4) (0/4) (2/4) True False +cofold 342.0 8.0 cofold Cofold predicts RNA secondary structures that takes co-transcriptional folding into account. To update http://www.e-rna.org/cofold/ RNA cofold rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/cofold 2.0.4.0 cofold 2.0.4 (0/1) (0/1) (1/1) True False +compalignp 220.0 compalignp Compute fractional identity between trusted alignment and test alignment Up-to-date RNA, Sequence Analysis compalignp rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/compalignp/ 1.0 compalignp 1.0 (0/1) (0/1) (1/1) True False +coprarna coprarna Target prediction for prokaryotic trans-acting small RNAs To update https://github.com/PatrickRWright/CopraRNA RNA, Sequence Analysis coprarna rnateam https://github.com/PatrickRWright/CopraRNA 2.1.1 coprarna 2.1.4 (0/1) (0/1) (0/1) True False +dewseq 72.0 11.0 dewseq DEWSeq is a sliding window based peak caller for eCLIP/iCLIP data To update https://github.com/EMBL-Hentze-group/DEWSeq_analysis_helpers Sequence Analysis, RNA, CLIP-seq dewseq rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/dewseq 0.1.0+galaxy0 python (0/1) (0/1) (1/1) True False +dorina 1086.0 1.0 dorina_search data source for RNA interactions in post-transcriptional regulation To update RNA, Data Source dorina rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/dorina/ 1.0 (0/1) (0/1) (1/1) True False +dot2ct rnastructure_dot2ct Dot-Bracket to Connect Table (CT) To update Sequence Analysis, RNA dot2ct rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/dot2ct 5.7.a rnastructure 6.4 (0/1) (0/1) (0/1) True False +dotknot 83.0 1.0 dotknot DotKnot is a heuristic method for pseudoknot prediction in a given RNA sequence To update http://dotknot.csse.uwa.edu.au/ RNA, Proteomics dotknot bgruening https://github.com/bgruening/galaxytools/tree/master/tools/rna/dotknot 1.3.1 vienna_rna (0/1) (0/1) (1/1) True False +exparna exparna ExpaRNA is a fast, motif-based comparison and alignment tool for RNA molecules. Up-to-date http://rna.informatik.uni-freiburg.de/ExpaRNA/Input.jsp RNA exparna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/exparna 1.0.1 exparna 1.0.1 (0/1) (0/1) (0/1) True False +graphprot graphprot_predict_profile GraphProt models binding preferences of RNA-binding proteins. To update https://github.com/dmaticzka/GraphProt Sequence Analysis, RNA, CLIP-seq graphprot rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/graphprot 1.1.7+galaxy1 graphprot 1.1.7 (0/1) (0/1) (1/1) True False +htseq-clip htseq_clip htseq-clip is a toolset for the analysis of eCLIP/iCLIP datasets To update https://github.com/EMBL-Hentze-group/htseq-clip Sequence Analysis, RNA, CLIP-seq htseq_clip rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/htseq-clip 0.1.0+galaxy0 htseq-clip 2.19.0b0 (0/1) (0/1) (1/1) True False +infernal 100230.0 67.0 infernal_cmalign, infernal_cmbuild, infernal_cmpress, infernal_cmscan, infernal_cmsearch, infernal_cmstat "Infernal (""INFERence of RNA ALignment"") is for searching DNA sequence databases for RNA structure and sequence similarities." infernal Infernal "Infernal (""INFERence of RNA ALignment"") is for searching DNA sequence databases for RNA structure and sequence similarities. It is an implementation of a special case of profile stochastic context-free grammars called covariance models (CMs). A CM is like a sequence profile, but it scores a combination of sequence consensus and RNA secondary structure consensus, so in many cases, it is more capable of identifying RNA homologs that conserve their secondary structure more than their primary sequence." Nucleic acid feature detection Sequence sites, features and motifs To update http://infernal.janelia.org/ RNA infernal bgruening https://github.com/bgruening/galaxytools/tree/master/tools/infernal 1.1.4 infernal 1.1.5 (0/6) (6/6) (6/6) True True +inforna INFO-RNA is a service for the design of RNA sequences that fold into a given pseudo-knot free RNA secondary structure. To update http://rna.informatik.uni-freiburg.de/INFORNA/Input.jsp RNA inforna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/inforna (0/1) (0/1) (0/1) True False +intarna 7569.0 23.0 intarna Efficient RNA-RNA interaction prediction incorporating accessibility and seeding of interaction sites. Up-to-date https://github.com/BackofenLab/IntaRNA RNA intarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/intarna 3.4.0 intarna 3.4.0 (0/1) (0/1) (1/1) True False +kinwalker 70.0 3.0 Kinwalker splits the folding process into a series of events where each event can either be a folding event or a transcription event. To update http://www.bioinf.uni-leipzig.de/Software/Kinwalker/ RNA kinwalker rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/kinwalker (0/1) (0/1) (0/1) True False +locarna locarna_exparnap, locarna_multiple, locarna_pairwise, locarna_pairwise_p, locarna_reliability_profile LocARNA - A suite for multiple alignment and folding of RNAs To update http://www.bioinf.uni-freiburg.de/Software/LocARNA/ RNA locarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/locarna 1.9.2.3 locarna 2.0.0 (0/5) (0/5) (1/5) True False +mea 85.0 3.0 mea Maximum expected accuracy prediction To update http://www.bioinf.uni-leipzig.de/Software/mea RNA mea rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/mea 0.6.4.1 mea 0.6.4 (0/1) (0/1) (1/1) True False +mqc 76.0 5.0 mqc Ribosome profiling mapping quality control tool To update https://github.com/Biobix/mQC Sequence Analysis mqc rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/mqc/ 1.9 mqc 1.10 (0/1) (0/1) (1/1) True False +nastiseq 40.0 nastiseq A method to identify cis-NATs using ssRNA-seq Up-to-date https://ohlerlab.mdc-berlin.de/software/NASTIseq_104/ RNA nastiseq rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/nastiseq 1.0 r-nastiseq 1.0 (0/1) (0/1) (1/1) True False +paralyzer 299.0 7.0 paralyzer A method to generate a high resolution map of interaction sites between RNA-binding proteins and their targets. Up-to-date https://ohlerlab.mdc-berlin.de/software/PARalyzer_85/ RNA paralyzer rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/paralyzer 1.5 paralyzer 1.5 (0/1) (0/1) (1/1) True False +pipmir 275.0 21.0 pipmir A method to identify novel plant miRNA. To update https://ohlerlab.mdc-berlin.de/software/Pipeline_for_the_Identification_of_Plant_miRNAs_84/ RNA pipmir rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/pipmir 0.1.0 pipmir 1.1 (0/1) (0/1) (1/1) True False +rRNA meta_rna Identification of ribosomal RNA genes in metagenomic fragments. To update http://weizhong-lab.ucsd.edu/meta_rna/ RNA rrna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rRNA 0.1 hmmsearch3.0 (0/1) (0/1) (0/1) True True +rbpbench 36.0 rbpbench Evaluate CLIP-seq and other genomic region data using a comprehensive collection of RBP binding motifs rbpbench RBPBench Evaluate CLIP-seq and other genomic region data using a comprehensive collection of RBP binding motifs RNA, Protein interactions, RNA immunoprecipitation, Bioinformatics, Sequence analysis Up-to-date https://github.com/michauhl/RBPBench Sequence Analysis, RNA, CLIP-seq rbpbench rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rbpbench 0.8.1 rbpbench 0.8.1 (0/1) (0/1) (1/1) False +rcas 1226.0 38.0 rcas RCAS (RNA Centric Annotation System) for functional analysis of transcriptome-wide regions detected by high-throughput experiments To update https://github.com/BIMSBbioinfo/RCAS RNA rcas rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rcas/ 1.5.4 bioconductor-rcas 1.28.2 (0/1) (0/1) (1/1) True False +reago reago Reago is tool to assembly 16S ribosomal RNA recovery from metagenomic data. Up-to-date https://github.com/chengyuan/reago-1.1 Metagenomics, RNA reago rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/reago 1.1 reago 1.1 (0/1) (0/1) (0/1) True True +remurna 42.0 2.0 remurna remuRNA - Measurement of Single Nucleotide Polymorphism induced Changes of RNA Conformation To update https://www.ncbi.nlm.nih.gov/CBBresearch/Przytycka/index.cgi#remurna RNA remurna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/remurna 1.0.0 remurna 1.0 (0/1) (0/1) (1/1) True False +ribotaper 628.0 44.0 ribotaper_create_annotation, ribotaper_create_metaplots, ribotaper_ribosome_profiling A method for defining traslated ORFs using Ribosome Profiling data. ribotaper RiboTaper New analysis pipeline for Ribosome Profiling (Ribo-seq) experiments, which exploits the triplet periodicity of ribosomal footprints to call translated regions. Gene expression profiling Functional genomics To update https://ohlerlab.mdc-berlin.de/software/RiboTaper_126/ RNA ribotaper rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/ribotaper/ 1.3.1a ribotaper 1.3.1 (0/3) (0/3) (3/3) True False +rna_shapes RNAshapes Compute secondary structures of RNA To update RNA rnashapes rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rna_shapes 3.3.0 @EXECUTABLE@ (0/1) (0/1) (1/1) True False +rnabob 164.0 3.0 rbc_rnabob Fast pattern searching for RNA structural motifs To update http://eddylab.org/software.html RNA rnabob rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rnabob 2.2.1.0 rnabob 2.2.1 (0/1) (0/1) (1/1) True False +rnacode 1358.0 5.0 rbc_rnacode Analyze the protein coding potential in MSA To update RNA rnacode rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rnacode 0.3.2 rnacode 0.3 (0/1) (0/1) (1/1) True False +rnacommender 1074.0 6.0 rbc_rnacommender RNAcommender is a tool for genome-wide recommendation of RNA-protein interactions. To update https://github.com/gianlucacorrado/RNAcommender RNA rnacommender rnateam https://github.com/bgruening/galaxytools/tree/rna_commander/tools/rna_tools/rna_commender 0.1.1 sam 3.5 (0/1) (0/1) (1/1) True False +rnalien 33.0 4.0 RNAlien RNAlien unsupervized RNA family model construction To update http://rna.tbi.univie.ac.at/rnalien/ RNA, Sequence Analysis rnalien rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/rnalien 1.3.6 rnalien 1.8.0 (0/1) (0/1) (1/1) True False +rnasnp 86.0 5.0 rnasnp RNAsnp Efficient detection of local RNA secondary structure changes induced by SNPs To update http://rth.dk/resources/rnasnp/ RNA rnasnp rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rnasnp 1.2.0 rnasnp 1.2 (0/1) (0/1) (1/1) True False +rnaz 42965.0 14.0 rnaz, rnaz_annotate, rnaz_cluster, rnaz_randomize_aln, rnaz_select_seqs, rnaz_window RNAz is a program for predicting structurally conserved and thermodynamically stable RNA secondary structures in multiple sequence alignments. Up-to-date https://www.tbi.univie.ac.at/~wash/RNAz/ RNA rnaz bgruening https://github.com/bgruening/galaxytools/tree/master/tools/rna_team/rnaz 2.1.1 rnaz 2.1.1 (0/6) (0/6) (6/6) True False +selectsequencesfrommsa 457.0 27.0 selectsequencesfrommsa SelectSequences - selects representative entries from a multiple sequence alignment in clustal format Up-to-date https://github.com/eggzilla/SelectSequences RNA, Sequence Analysis selectsequencesfrommsa rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/selectsequencesfrommsa 1.0.5 selectsequencesfrommsa 1.0.5 (0/1) (0/1) (1/1) True False +sortmerna 18504.0 376.0 bg_sortmerna SortMeRNA is a software designed to rapidly filter ribosomal RNA fragments from metatransriptomic data produced by next-generation sequencers. sortmerna SortMeRNA Sequence analysis tool for filtering, mapping and OTU-picking NGS reads. Sequence similarity search, Sequence comparison, Sequence alignment analysis Metatranscriptomics, Metagenomics Up-to-date http://bioinfo.lifl.fr/RNA/sortmerna/ RNA sortmerna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/sortmerna 4.3.6 sortmerna 4.3.6 (1/1) (1/1) (1/1) True True +sshmm 223.0 5.0 sshmm ssHMM is an RNA sequence-structure motif finder for RNA-binding protein data, such as CLIP-Seq data Up-to-date https://github.molgen.mpg.de/heller/ssHMM Sequence Analysis, RNA sshmm rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/sshmm/ 1.0.7 sshmm 1.0.7 (0/1) (0/1) (1/1) True False +targetfinder 713.0 37.0 targetfinder Plant small RNA target prediction tool Up-to-date https://github.com/carringtonlab/TargetFinder.git RNA targetfinder rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/targetfinder/ 1.7 targetfinder 1.7 (1/1) (1/1) (1/1) True False +trna_prediction 2935.0 236.0 aragorn_trna, trnascan Aragorn predicts tRNA and tmRNA in nucleotide sequences. To update http://mbioserv2.mbioekol.lu.se/ARAGORN/ RNA trna_prediction bgruening https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/trna_prediction 0.6 aragorn 1.2.41 (0/2) (2/2) (2/2) True False +vienna_rna 799.0 viennarna_kinfold, viennarna_kinwalker, viennarna_rna2dfold, viennarna_rnaaliduplex, viennarna_rnaalifold, viennarna_rnacofold, viennarna_rnadistance, viennarna_rnaduplex, viennarna_rnaeval, viennarna_rnafold, viennarna_rnaheat, viennarna_rnainverse, viennarna_rnalalifold, viennarna_rnalfold, viennarna_rnapaln, viennarna_rnadpdist, viennarna_rnapkplex, viennarna_rnaplex, viennarna_rnaplfold, viennarna_rnaplot, viennarna_rnasnoop, viennarna_rnasubopt, viennarna_rnaup ViennaRNA - Prediction and comparison of RNA secondary structures To update http://www.tbi.univie.ac.at/RNA/ RNA viennarna rnateam https://github.com/bgruening/galaxytools/tree/master/tools/rna_tools/vienna_rna 2.2.10 viennarna 2.6.4 (0/23) (0/23) (21/23) True False +sailfish 4024.0 55.0 sailfish Sailfish is a tool for transcript quantification from RNA-seq data To update http://www.cs.cmu.edu/~ckingsf/software/sailfish/ Sequence Analysis, RNA sailfish bgruening https://github.com/bgruening/galaxytools/tree/master/tools/sailfish 0.10.1.1 bzip2 (1/1) (1/1) (1/1) True False +salmon 55161.0 746.0 alevin, salmon, salmonquantmerge Salmon is a wicked-fast program to produce a highly-accurate, transcript-level quantification estimates from RNA-seq and single-cell data. To update https://github.com/COMBINE-lab/salmon Sequence Analysis, RNA, Transcriptomics bgruening https://github.com/bgruening/galaxytools/tree/master/tools/salmon 1.10.1 salmon 1.10.2 (2/3) (1/3) (3/3) True True +tapscan tapscan_classify Search for transcription associated proteins (TAPs) To update https://plantcode.cup.uni-freiburg.de/tapscan/ Proteomics tapscan bgruening https://github.com/bgruening/galaxytools/tree/master/tools/tapscan 4.76+galaxy0 hmmer 3.4 (0/1) (0/1) (1/1) False +tgsgapcloser 460.0 36.0 tgsgapcloser TGS-GapCloser uses error-prone long reads or preassembled contigs to fill N-gap in the genome assembly. TGS-GapCloser TGS-GapCloser TGS-GapCloser is a fast and accurately passing through the Bermuda in large genome using error-prone third-generation long reads. Genome assembly, Read mapping, Scaffolding, Localised reassembly Sequencing, Sequence assembly, Phylogeny, Transcription factors and regulatory sites, Mapping To update https://github.com/BGI-Qingdao/TGS-GapCloser Assembly tgsgapcloser bgruening https://github.com/bgruening/galaxytools/tree/master/tools/tgsgapcloser 1.0.3 tgsgapcloser 1.2.1 (0/1) (0/1) (1/1) True False +trim_galore 238699.0 2334.0 trim_galore Trim Galore adaptive quality and adapter trimmer trim_galore Trim Galore A wrapper tool around Cutadapt and FastQC to consistently apply quality and adapter trimming to FastQ files, with some extra functionality for MspI-digested RRBS-type (Reduced Representation Bisufite-Seq) libraries. Sequence trimming Sequence analysis To update http://www.bioinformatics.babraham.ac.uk/projects/trim_galore/ Sequence Analysis, Fastq Manipulation trim_galore bgruening https://github.com/bgruening/galaxytools/tree/master/tools/trim_galore 0.6.7 trim-galore 0.6.10 (1/1) (1/1) (1/1) True True +uniprot_rest_interface 2406.0 132.0 uniprot UniProt ID mapping and sequence retrieval To update https://github.com/jdrudolph/uniprot Proteomics, Sequence Analysis uniprot_rest_interface bgruening https://github.com/bgruening/galaxytools/tree/master/tools/uniprot_rest_interface 0.4 requests (1/1) (1/1) (1/1) True False +vt vt_@BINARY@, vt_@BINARY@ A tool set for short variant discovery in genetic sequence data. To update Sequence Analysis, Variant Analysis vt bgruening https://github.com/atks/vt 0.2 vt 2015.11.10 (0/1) (0/1) (0/1) True False +wtdbg 1660.0 116.0 wtdbg WTDBG is a fuzzy Bruijn graph (FBG) approach to long noisy reads assembly. wtdbg2 wtdbg2 Wtdbg2 is a de novo sequence assembler for long noisy reads produced by PacBio or Oxford Nanopore Technologies (ONT). It assembles raw reads without error correction and then builds the consensus from intermediate assembly output. Wtdbg2 is able to assemble the human and even the 32Gb Axolotl genome at a speed tens of times faster than CANU and FALCON while producing contigs of comparable base accuracy. Genome assembly, De-novo assembly Sequence assembly, Sequencing Up-to-date https://github.com/ruanjue/wtdbg2 Assembly wtdbg bgruening https://github.com/bgruening/galaxytools/tree/master/tools/wtdbg 2.5 wtdbg 2.5 (0/1) (0/1) (1/1) True True +align_back_trans 329.0 11.0 align_back_trans Thread nucleotides onto a protein alignment (back-translation) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/align_back_trans Fasta Manipulation, Sequence Analysis align_back_trans peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/align_back_trans 0.0.10 biopython 1.70 (0/1) (0/1) (1/1) True False +chromosome_diagram chromosome_diagram Chromosome Diagrams using Biopython To update Graphics, Sequence Analysis, Visualization chromosome_diagram peterjc 0.0.3 biopython 1.70 (0/1) (0/1) (0/1) True False +clc_assembly_cell clc_assembler, clc_mapper Galaxy wrapper for the CLC Assembly Cell suite from CLCBio To update https://github.com/peterjc/pico_galaxy/tree/master/tools/clc_assembly_cell Assembly, Next Gen Mappers, SAM clc_assembly_cell peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/clc_assembly_cell 0.0.7 samtools 1.19.2 (0/2) (0/2) (0/2) True False +clinod clinod NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins To update http://www.compbio.dundee.ac.uk/www-nod/ Sequence Analysis clinod peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/clinod 0.1.0 clinod 1.3 (1/1) (0/1) (0/1) True True +count_roi_variants count_roi_variants Count sequence variants in region of interest in BAM file To update https://github.com/peterjc/pico_galaxy/tree/master/tools/count_roi_variants Assembly, SAM count_roi_variants peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/count_roi_variants 0.0.6 samtools 1.19.2 (0/1) (0/1) (0/1) True False +coverage_stats coverage_stats BAM coverage statistics using samtools idxstats and depth To update https://github.com/peterjc/pico_galaxy/tree/master/tools/coverage_stats Assembly, SAM coverage_stats peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/coverage_stats 0.1.0 samtools 1.19.2 (0/1) (0/1) (0/1) True False +effectiveT3 effectiveT3 Find bacterial type III effectors in protein sequences To update http://effectors.org Sequence Analysis effectivet3 peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/effectiveT3 0.0.20 effectiveT3 1.0.1 (0/1) (0/1) (0/1) True True +fasta_filter_by_id fasta_filter_by_id Filter FASTA sequences by ID (DEPRECATED) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/fasta_filter_by_id Fasta Manipulation, Sequence Analysis, Text Manipulation fasta_filter_by_id peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/fasta_filter_by_id 0.0.7 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False +fastq_filter_by_id fastq_filter_by_id Filter FASTQ sequences by ID (DEPRECATED) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_filter_by_id Fastq Manipulation, Sequence Analysis, Text Manipulation fastq_filter_by_id peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_filter_by_id 0.0.7 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False +fastq_pair_names fastq_pair_names Extract FASTQ paired read names To update https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_pair_names Sequence Analysis fastq_pair_names peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_pair_names 0.0.5 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False +fastq_paired_unpaired fastq_paired_unpaired Divide FASTQ file into paired and unpaired reads To update https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_paired_unpaired Sequence Analysis, Text Manipulation fastq_paired_unpaired peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/fastq_paired_unpaired 0.1.5 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False +get_orfs_or_cdss 7.0 get_orfs_or_cdss Search nucleotide sequences for open reading frames (ORFs), or coding sequences (CDSs) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/get_orfs_or_cdss Sequence Analysis get_orfs_or_cdss peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/get_orfs_or_cdss 0.2.3 biopython 1.70 (0/1) (1/1) (1/1) True False +mummer 652.0 83.0 mummerplot_wrapper Draw dotplots using mummer, mucmer, or promer with mummerplot To update http://mummer.sourceforge.net/ Graphics, Sequence Analysis, Visualization mummer peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/mummer 0.0.8 ghostscript 9.18 (1/1) (0/1) (1/1) True False +nlstradamus nlstradamus Find nuclear localization signals (NLSs) in protein sequences To update http://www.moseslab.csb.utoronto.ca/NLStradamus Fasta Manipulation, Sequence Analysis nlstradamus peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/nlstradamus 0.0.11 NLStradamus 1.8 (0/1) (0/1) (0/1) True False +predictnls predictnls Python reimplementation of predictNLS for Galaxy To update https://github.com/peterjc/pico_galaxy/tree/master/tools/predictnls Sequence Analysis predictnls peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/predictnls 0.0.10 (0/1) (0/1) (0/1) True False +protein_analysis promoter2, Psortb, rxlr_motifs, signalp3, tmhmm2, wolf_psort TMHMM, SignalP, Promoter, RXLR motifs, WoLF PSORT and PSORTb To update https://github.com/peterjc/pico_galaxy/tree/master/tools/protein_analysis Sequence Analysis tmhmm_and_signalp peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/protein_analysis 0.0.13 promoter (0/6) (0/6) (6/6) True False +sample_seqs 3765.0 149.0 sample_seqs Sub-sample sequences files (e.g. to reduce coverage) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/sample_seqs Assembly, Fasta Manipulation, Fastq Manipulation, Sequence Analysis sample_seqs peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/sample_seqs 0.2.6 biopython 1.70 (1/1) (1/1) (1/1) True False +samtools_depad samtools_depad Re-align a SAM/BAM file with a padded reference (using samtools depad) To update http://www.htslib.org/ Assembly, SAM, Sequence Analysis samtools_depad peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/samtools_depad 0.0.5 samtools 1.19.2 (0/1) (0/1) (0/1) True False +samtools_depth 4948.0 296.0 samtools_depth Coverage depth via samtools To update http://www.htslib.org/ Assembly, Sequence Analysis, SAM samtools_depth peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/samtools_depth 0.0.3 samtools 1.19.2 (1/1) (1/1) (1/1) True False +samtools_idxstats 48426.0 1450.0 samtools_idxstats BAM mapping statistics (using samtools idxstats) To update http://www.htslib.org/ Assembly, Next Gen Mappers, SAM samtools_idxstats peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/samtools_idxstats 0.0.6 samtools 1.19.2 (1/1) (1/1) (1/1) True False +seq_composition 874.0 71.0 seq_composition Sequence composition To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_composition Sequence Analysis seq_composition peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_composition 0.0.5 biopython 1.70 (1/1) (0/1) (1/1) True False +seq_filter_by_id 25302.0 306.0 seq_filter_by_id Filter sequences by ID To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_filter_by_id Fasta Manipulation, Sequence Analysis, Text Manipulation seq_filter_by_id peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_filter_by_id 0.2.9 biopython 1.70 (1/1) (1/1) (1/1) True False +seq_filter_by_mapping 3784.0 82.0 seq_filter_by_mapping Filter sequencing reads using SAM/BAM mapping files To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_filter_by_mapping Assembly, Fasta Manipulation, Fastq Manipulation, SAM, Sequence Analysis seq_filter_by_mapping peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_filter_by_mapping 0.0.8 biopython 1.70 (0/1) (0/1) (1/1) True False +seq_length seq_length Compute sequence length (from FASTA, QUAL, FASTQ, SFF, etc) To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_length Fasta Manipulation, Fastq Manipulation, Sequence Analysis seq_length peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_length 0.0.5 biopython 1.70 (0/1) (0/1) (0/1) True False +seq_primer_clip seq_primer_clip Trim off 5' or 3' primers To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_primer_clip Assembly, Fasta Manipulation, Text Manipulation seq_primer_clip peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_primer_clip 0.0.18 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False +seq_rename seq_rename Rename sequences with ID mapping from a tabular file To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_rename Fasta Manipulation, Sequence Analysis, Text Manipulation seq_rename peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_rename 0.0.10 galaxy_sequence_utils 1.1.5 (0/1) (0/1) (0/1) True False +seq_select_by_id seq_select_by_id Select sequences by ID To update https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_select_by_id Fasta Manipulation, Sequence Analysis, Text Manipulation seq_select_by_id peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/seq_select_by_id 0.0.15 biopython 1.70 (0/1) (1/1) (0/1) True False +venn_list 5067.0 248.0 venn_list Draw Venn Diagram (PDF) from lists, FASTA files, etc To update https://github.com/peterjc/pico_galaxy/tree/master/tools/venn_list Graphics, Sequence Analysis, Visualization venn_list peterjc https://github.com/peterjc/pico_galaxy/tree/master/tools/venn_list 0.1.2 galaxy_sequence_utils 1.1.5 (1/1) (0/1) (1/1) True False +TrimNs trimns TrimNs is used to trim and remove fake cut sites from bionano hybrid scaffold data in the VGP pipeline To update https://github.com/VGP/vgp-assembly/tree/master/pipeline/bionano/trimNs Assembly trimns iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/trimN 0.1.0 trimns_vgp 1.0 (0/1) (0/1) (1/1) True False +abricate 496717.0 1764.0 abricate, abricate_list, abricate_summary Mass screening of contigs for antiobiotic resistance genes ABRicate ABRicate Mass screening of contigs for antimicrobial resistance or virulence genes. Antimicrobial resistance prediction Genomics, Microbiology Up-to-date https://github.com/tseemann/abricate Sequence Analysis abricate iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/abricate/ 1.0.1 abricate 1.0.1 (3/3) (3/3) (3/3) True True +abritamr abritamr A pipeline for running AMRfinderPlus and collating results into functional classes Up-to-date https://zenodo.org/record/7370628 Sequence Analysis abritamr iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/abritamr 1.0.14 abritamr 1.0.14 (0/1) (0/1) (0/1) True True +abyss 4278.0 391.0 abyss-pe Assembly By Short Sequences - a de novo, parallel, paired-end sequence assembler abyss ABySS De novo genome sequence assembler using short reads. Genome assembly, De-novo assembly, Scaffolding Sequence assembly Up-to-date http://www.bcgsc.ca/platform/bioinfo/software/abyss Assembly abyss iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/abyss 2.3.7 abyss 2.3.7 (0/1) (1/1) (1/1) True True +adapter_removal 217.0 37.0 adapter_removal Removes residual adapter sequences from single-end (SE) or paired-end (PE) FASTQ reads. adapterremoval AdapterRemoval AdapterRemoval searches for and removes adapter sequences from High-Throughput Sequencing (HTS) data and (optionally) trims low quality bases from the 3' end of reads following adapter removal. AdapterRemoval can analyze both single end and paired end data, and can be used to merge overlapping paired-ended reads into (longer) consensus sequences. Additionally, AdapterRemoval can construct a consensus adapter sequence for paired-ended reads, if which this information is not available. Sequence trimming, Sequence merging, Primer removal Up-to-date https://github.com/MikkelSchubert/adapterremoval Fasta Manipulation, Sequence Analysis adapter_removal iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/adapter_removal/ 2.3.3 adapterremoval 2.3.3 (0/1) (0/1) (1/1) True False +aegean aegean_canongff3, aegean_gaeval, aegean_locuspocus, aegean_parseval AEGeAn toolkit wrappers gaeval GAEVAL Gene Annotation EVAluation. Sequence annotation Sequence analysis, Gene structure Up-to-date https://github.com/BrendelGroup/AEGeAn Transcriptomics, Sequence Analysis aegean iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/aegean 0.16.0 aegean 0.16.0 (1/4) (4/4) (4/4) True False +aldex2 129.0 13.0 aldex2 Performs analysis Of differential abundance taking sample variation into account aldex2 ALDEx2 A differential abundance analysis for the comparison of two or more conditions. It uses a Dirichlet-multinomial model to infer abundance from counts, that has been optimized for three or more experimental replicates. Infers sampling variation and calculates the expected FDR given the biological and sampling variation using the Wilcox rank test and Welches t-test, or the glm and Kruskal Wallis tests. Reports both P and fdr values calculated by the Benjamini Hochberg correction. Statistical inference Gene expression, Statistics and probability To update https://github.com/ggloor/ALDEx_bioc Metagenomics aldex2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/aldex2 1.26.0 bioconductor-aldex2 1.34.0 (0/1) (0/1) (1/1) True True +amplican 53.0 12.0 amplican AmpliCan is an analysis tool for genome editing. amplican amplican It performs alignment of the amplicon reads, normalizes gathered data, calculates multiple statistics (e.g. cut rates, frameshifts) and presents results in form of aggregated reports. Data and statistics can be broken down by experiments, barcodes, user defined groups, guides and amplicons allowing for quick identification of potential problems. Alignment, Standardisation and normalisation PCR experiment, Statistics and probability To update https://github.com/valenlab/amplican Sequence Analysis amplican iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/amplican 1.14.0 bioconductor-amplican 1.24.0 (0/1) (0/1) (1/1) True True +ampvis2 ampvis2_alpha_diversity, ampvis2_boxplot, ampvis2_core, ampvis2_export_fasta, ampvis2_frequency, ampvis2_heatmap, ampvis2_load, ampvis2_merge_ampvis2, ampvis2_mergereplicates, ampvis2_octave, ampvis2_ordinate, ampvis2_otu_network, ampvis2_rankabundance, ampvis2_rarecurve, ampvis2_setmetadata, ampvis2_subset_samples, ampvis2_subset_taxa, ampvis2_timeseries, ampvis2_venn ampvis2 ampvis ampvis ampvis2 is an R-package to conveniently visualise and analyse 16S rRNA amplicon data in different ways. Analysis, Visualisation Biodiversity To update https://github.com/MadsAlbertsen/ampvis2/ Metagenomics ampvis2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ampvis2 2.8.6 (0/19) (0/19) (19/19) True False +amrfinderplus 591.0 amrfinderplus """AMRFinderPlus is designed to find acquired antimicrobial resistance genes and point mutations in protein and/or assembled nucleotide sequences.It can also search ""plus"", stress, heat, and biocide resistance and virulence factors for some organisms." amrfinderplus AMRFinderPlus "AMRFinderPlus is designed to find acquired antimicrobial resistance genes and point mutations in protein and/or assembled nucleotide sequences.It can also search ""plus"", stress, heat, and biocide resistance and virulence factors for some organisms" Antimicrobial resistance prediction Microbiology, Public health and epidemiology, Infectious disease To update https://github.com/ncbi/amr Sequence Analysis AMRFinderPlus iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/amrfinderplus 3.11.26 ncbi-amrfinderplus 3.12.8 (0/1) (0/1) (1/1) True True +ancombc 7.0 4.0 ancombc Performs analysis of compositions of microbiomes with bias correction. ancombc ANCOMBC Determine taxa whose absolute abundances, per unit volume, of the ecosystem (e.g. gut) are significantly different with changes in the covariate of interest (e.g. group). The current version of ancombc function implements Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC) in cross-sectional data while allowing for covariate adjustment. DNA barcoding Microbial ecology, Metagenomics To update https://github.com/FrederickHuangLin/ANCOMBC Metagenomics ancombc iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ancombc 1.4.0 bioconductor-ancombc 2.4.0 (0/1) (0/1) (1/1) True True +anndata anndata_export, anndata_import, anndata_inspect, anndata_manipulate, modify_loom Import, Export, Inspect and Manipulate Anndata and Loom objects To update https://anndata.readthedocs.io Transcriptomics, Sequence Analysis anndata iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/anndata/ 0.10.3 anndata 0.6.22.post1 (5/5) (4/5) (5/5) True False +annotatemyids 26115.0 1175.0 annotatemyids annotateMyIDs: get annotation for a set of IDs using the Bioconductor annotation packages annotatemyids annotatemyids This tool can get annotation for a generic set of IDs, using the Bioconductor annotation data packages. Supported organisms are human, mouse, rat, fruit fly and zebrafish. The org.db packages that are used here are primarily based on mapping using Entrez Gene identifiers. More information on the annotation packages can be found at the Bioconductor website, for example, information on the human annotation package (org.Hs.eg.db) can be found here. Annotation Up-to-date https://github.com/galaxyproject/tools-iuc/tree/master/tools/annotatemyids Genome annotation annotatemyids iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/annotatemyids 3.18.0 bioconductor-org.hs.eg.db 3.18.0 (1/1) (1/1) (1/1) True False +arriba 3436.0 28.0 arriba, arriba_draw_fusions, arriba_get_filters Arriba detects fusion genes in RNA-Seq data after running RNA-STAR Up-to-date https://github.com/suhrig/arriba Sequence Analysis, Transcriptomics arriba iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/arriba 2.4.0 arriba 2.4.0 (0/3) (3/3) (3/3) True False +art art_454, art_illumina, art_solid Simulator for Illumina, 454, and SOLiD sequencing data art ART ART is a set of simulation tools to generate synthetic next-generation sequencing reads. ART simulates sequencing reads by mimicking real sequencing process with empirical error models or quality profiles summarized from large recalibrated sequencing data. ART can also simulate reads using user own read error model or quality profiles. ART supports simulation of single-end, paired-end/mate-pair reads of three major commercial next-generation sequencing platforms. Illuminas Solexa, Roches 454 and Applied Biosystems SOLiD Conversion Bioinformatics To update Sequence Analysis, Data Source art iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/art 2014.11.03.0 art 2016.06.05 (0/3) (0/3) (0/3) True False +artic artic_guppyplex, artic_minion The artic pipeline is designed to help run the artic bioinformatics protocols;for example the nCoV-2019 novel coronavirus protocol.Features include: read filtering, primer trimming, amplicon coverage normalisation,variant calling and consensus building artic ARTIC A bioinformatics pipeline for working with virus sequencing data sequenced with nanopore Sequence alignment Genomics To update https://github.com/artic-network/fieldbioinformatics Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/artic artic 1.2.4 (0/2) (0/2) (2/2) True True +assembly-stats assembly_stats Assembly metric visualisations to facilitate rapid assessment and comparison of assembly quality. Up-to-date https://github.com/rjchallis/assembly-stats Assembly assembly_stats iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/assembly-stats 17.02 rjchallis-assembly-stats 17.02 (0/1) (0/1) (0/1) True False +augustus 8864.0 516.0 augustus, augustus_training AUGUSTUS is a program that predicts genes in eukaryotic genomic sequences. augustus AUGUSTUS AUGUSTUS is a eukaryotic gene prediction tool. It can integrate evidence, e.g. from RNA-Seq, ESTs, proteomics, but can also predict genes ab initio. The PPX extension to AUGUSTUS can take a protein sequence multiple sequence alignment as input to find new members of the family in a genome. It can be run through a web interface (see https://bio.tools/webaugustus), or downloaded and run locally. Gene prediction, Ab-initio gene prediction, Homology-based gene prediction, Homology-based gene prediction, Operation Gene transcripts, Gene and protein families To update http://bioinf.uni-greifswald.de/augustus/ Sequence Analysis augustus bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/augustus 3.4.0 augustus 3.5.0 (2/2) (2/2) (2/2) True False +b2btools b2btools_single_sequence This software suite provides structural predictions for protein sequences made by Bio2Byte group.About Bio2Byte: We investigate how the dynamics, conformational states, and available experimental data of proteins relate to their amino acid sequence.Underlying physical and chemical principles are computationally unraveled through data integration, analysis, and machine learning, so connecting themto biological events and improving our understanding of the way proteins work. b2btools b2bTools The bio2byte tools server (b2btools) offers the following single protein sequence based predictions:- Backbone and sidechain dynamics (DynaMine)- Helix, sheet, coil and polyproline-II propensity- Early folding propensity (EFoldMine)- Disorder (DisoMine)- Beta-sheet aggregation (Agmata)In addition, multiple sequence alignments (MSAs) can be uploaded to scan the 'biophysical limits' of a protein family as defined in the MSA Protein disorder prediction, Protein secondary structure prediction, Protein feature detection To update https://bio2byte.be Computational chemistry, Molecular Dynamics, Proteomics, Sequence Analysis, Synthetic Biology iuc 3.0.5+galaxy0 b2btools 3.0.6 (0/1) (0/1) (1/1) True False +bakta 2982.0 151.0 bakta """Bakta is a tool for the rapid & standardized annotation of bacterial genomes and plasmids from both isolates and MAGs.It provides dbxref-rich and sORF-including annotations in machine-readable JSON & bioinformatics standard file formats for automatic downstream analysis.""" Bakta Bakta Rapid & standardized annotation of bacterial genomes, MAGs & plasmids Genome annotation Genomics, Data submission, annotation and curation, Sequence analysis Up-to-date https://github.com/oschwengers/bakta Sequence Analysis bakta iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/bakta 1.9.2 bakta 1.9.2 (0/1) (1/1) (1/1) True True +bamutil bamutil_clip_overlap, bamutil_diff bamUtil is a repository that contains several programs that perform operations on SAM/BAM files. To update https://github.com/statgen/bamUtil Sequence Analysis bamutil iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bamutil bamutil 1.0.15 (1/2) (1/2) (1/2) True False +bandage 44390.0 2016.0 bandage_image, bandage_info Bandage - A Bioinformatics Application for Navigating De novo Assembly Graphs Easily bandage Bandage GUI program that allows users to interact with the assembly graphs made by de novo assemblers such as Velvet, SPAdes, MEGAHIT and others. It visualises assembly graphs, with connections, using graph layout algorithms. Sequence assembly visualisation Genomics, Sequence assembly Up-to-date https://github.com/rrwick/Bandage Visualization bandage iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bandage 2022.09 bandage_ng 2022.09 (2/2) (2/2) (2/2) True True +baredsc baredsc_1d, baredsc_2d, baredsc_combine_1d, baredsc_combine_2d baredSC is a tool that uses a Monte-Carlo Markov Chain to estimate a confidence interval on the probability density function (PDF) of expression of one or two genes from single-cell RNA-seq data. baredsc baredSC The baredSC (Bayesian Approach to Retreive Expression Distribution of Single Cell) is a tool that uses a Monte-Carlo Markov Chain to estimate a confidence interval on the probability density function (PDF) of expression of one or two genes from single-cell RNA-seq data. Data retrieval, Expression correlation analysis, Differential gene expression profiling RNA-Seq, Cytometry, Transcriptomics, Gene transcripts, Statistics and probability Up-to-date https://github.com/lldelisle/baredSC Transcriptomics, Visualization baredsc iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/baredsc 1.1.2 baredsc 1.1.2 (4/4) (0/4) (4/4) True False +barrnap 3938.0 160.0 barrnap Contains the Barrnap tool for finding ribosomal RNAs in FASTA sequences. barrnap Barrnap Predict the location of ribosomal RNA genes in genomes. It supports bacteria (5S,23S,16S), archaea (5S,5.8S,23S,16S), mitochondria (12S,16S) and eukaryotes (5S,5.8S,28S,18S). Gene prediction Genomics, Model organisms, Model organisms To update Sequence Analysis barrnap iuc 1.2.2 barrnap 0.9 (0/1) (1/1) (1/1) True False +bax2bam 200.0 8.0 bax2bam BAX to BAM converter Up-to-date https://github.com/pacificbiosciences/bax2bam/ Convert Formats, Sequence Analysis bax2bam iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pax2bam 0.0.11 bax2bam 0.0.11 (1/1) (0/1) (1/1) True False +bayescan 64.0 8.0 BayeScan Detecting natural selection from population-based genetic data bayescan BayeScan BAYEsian genome SCAN for outliers, aims at identifying candidate loci under natural selection from genetic data, using differences in allele frequencies between populations. It is based on the multinomial-Dirichlet model. Statistical inference Genetics, Evolutionary biology, Statistics and probability, DNA polymorphism To update http://cmpg.unibe.ch/software/BayeScan/index.html Sequence Analysis bayescan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bayescan/ 2.1 bayescan 2.0.1 (0/1) (0/1) (1/1) True True +bbtools bbtools_bbduk, bbtools_bbmap, bbtools_bbmerge, bbtools_bbnorm, bbtools_callvariants, bbtools_tadpole BBTools is a suite of fast, multithreaded bioinformatics tools designed for analysis of DNA and RNA sequence data.BBTools can handle common sequencing file formats such as fastq, fasta, sam, scarf, fasta+qual, compressed or raw,with autodetection of quality encoding and interleaving. It is written in Java and works on any platform supportingJava, including Linux, MacOS, and Microsoft Windows and Linux; there are no dependencies other than Java (version7 or higher). Program descriptions and options are shown when running the shell scripts with no parameters. Up-to-date https://jgi.doe.gov/data-and-tools/bbtools/ Sequence Analysis bbtools iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bbtools 39.06 bbmap 39.06 (6/6) (1/6) (5/6) True False +bctools bctools_convert_to_binary_barcode, bctools_extract_crosslinked_nucleotides, bctools_extract_alignment_ends, bctools_extract_barcodes, bctools_merge_pcr_duplicates, bctools_remove_tail, bctools_remove_spurious_events bctools is a set of tools for handling barcodes and UMIs in NGS data.bctools can be used to merge PCR duplicates according to unique molecular barcodes (UMIs),to extract barcodes from arbitrary positions relative to the read starts,to clean up readthroughs into UMIs with paired-end sequencing andhandles binary barcodes as used with uvCLAP and FLASH.License: Apache License 2.0 Up-to-date https://github.com/dmaticzka/bctools Sequence Analysis, Transcriptomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bedtools 0.2.2 bctools 0.2.2 (0/7) (0/7) (7/7) True False +bellerophon 1194.0 123.0 bellerophon Filter mapped reads where the mapping spans a junction, retaining the 5-prime read. Up-to-date https://github.com/davebx/bellerophon Sequence Analysis bellerophon iuc https://github.com/davebx/bellerophon 1.0 bellerophon 1.0 (1/1) (1/1) (1/1) True False +bigscape bigscape Construct sequence similarity networks of BGCs and groups them into GCF Up-to-date https://github.com/medema-group/BiG-SCAPE Metagenomics bigscape iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bigscape/ 1.1.9 bigscape 1.1.9 (0/1) (0/1) (0/1) False +binning_refiner 81.0 21.0 bin_refiner Reconciles the outputs of different binning programs with the aim to improve the quality of genome bins,especially with respect to contamination levels. binning_refiner Binning_refiner Improving genome bins through the combination of different binning programs Read binning, Sequence clustering Metagenomics Up-to-date https://github.com/songweizhi/Binning_refiner Metagenomics binning_refiner iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/binning_refiner/ 1.4.3 binning_refiner 1.4.3 (0/1) (0/1) (1/1) True True +bioinformatics_cafe fasta_regex_finder Miscellanea of scripts for bioinformatics To update https://github.com/dariober/bioinformatics-cafe/ Sequence Analysis bioinformatics_cafe mbernt https://github.com/galaxyproject/tools-iuc/tree/main/tools/bioinformatics-cafe 0.1.0 python (1/1) (0/1) (1/1) True False +biom_format biom_add_metadata, biom_convert, biom_from_uc, biom_normalize_table, biom_subset_table, biom_summarize_table The biom-format package provides a command line interface and Python API for working with BIOM files. biomformat biomformat "This package includes basic tools for reading biom-format files, accessing and subsetting data tables from a biom object, as well as limited support for writing a biom-object back to a biom-format file. The design of this API is intended to match the python API and other tools included with the biom-format project, but with a decidedly ""R flavor"" that should be familiar to R users. This includes S4 classes and methods, as well as extensions of common core functions/methods." Formatting Laboratory information management, Sequence analysis To update https://github.com/biocore/biom-format Metagenomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/biom_format 2.1.15 biom-format 2.1.7 (2/6) (2/6) (1/6) True True +bioperl bp_genbank2gff3 Converts GenBank format files to GFF3 bioperl BioPerl A collection of Perl modules that facilitate the development of Perl scripts for bioinformatics applications. It provides software modules for many of the typical tasks of bioinformatics programming. Data handling, Service invocation Genomics, Software engineering, Data management To update https://bioperl.org/ Sequence Analysis bp_genbank2gff3 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bioperl 1.1 perl-bioperl 1.7.8 (1/1) (1/1) (1/1) True False +biscot 3.0 1.0 biscot Bionano scaffolding correction tool Up-to-date https://github.com/institut-de-genomique/biscot Assembly biscot iuc https://github.com/bgruening/iuc/tree/master/tools/biscot 2.3.3 biscot 2.3.3 (0/1) (0/1) (1/1) True False +blastxml_to_gapped_gff3 185.0 24.0 blastxml_to_gapped_gff3 BlastXML to gapped GFF3 To update Convert Formats, Sequence Analysis blastxml_to_gapped_gff3 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/blastxml_to_gapped_gff3 1.1 bcbiogff 0.6.6 (1/1) (1/1) (1/1) True False +bracken 18351.0 326.0 est_abundance Bayesian Reestimation of Abundance with KrakEN bracken Bracken Statistical method that computes the abundance of species in DNA sequences from a metagenomics sample. Statistical calculation Metagenomics, Microbial ecology Up-to-date https://ccb.jhu.edu/software/bracken/ Sequence Analysis, Metagenomics bracken iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bracken 2.9 bracken 2.9 (0/1) (0/1) (1/1) True True +busco 86180.0 1804.0 busco BUSCO assess genome and annotation completeness busco BUSCO Provides measures for quantitative assessment of genome assembly, gene set, and transcriptome completeness based on evolutionarily informed expectations of gene content from near-universal single-copy orthologs. Sequence assembly validation, Scaffolding, Genome assembly, Transcriptome assembly Sequence assembly, Genomics, Transcriptomics, Sequence analysis To update https://gitlab.com/ezlab/busco/-/releases Sequence Analysis busco iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/busco/ 5.5.0 busco 5.6.1 (1/1) (1/1) (1/1) True True +bwameth 10619.0 201.0 bwameth Fast and accurate alignment of BS-seq reads To update https://github.com/brentp/bwa-meth Sequence Analysis, Next Gen Mappers bwameth iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/bwameth 0.2.6 bwameth 0.2.7 (1/1) (1/1) (1/1) True False +cactus cactus_cactus, cactus_export Cactus is a reference-free whole-genome multiple alignment program cactus Cactus Cactus is a reference-free whole-genome multiple alignment program. Multiple sequence alignment, Genome alignment Genomics, Sequence analysis, Phylogeny, Sequence assembly, Mapping, Phylogenetics To update https://github.com/ComparativeGenomicsToolkit/cactus Sequence Analysis cactus galaxy-australia https://github.com/galaxyproject/tools-iuc/tree/main/tools/cactus 2.7.1 (0/2) (2/2) (2/2) False +calculate_contrast_threshold calculate_contrast_threshold Calculates a contrast threshold from the CDT file generated by ``tag_pileup_frequency``. The calculated values are then used to set a uniform contrast for all the heatmaps generated downstream. To update https://github.com/CEGRcode/ChIP-QC-tools/tree/master/calculate_contrast_threshold Visualization, Genomic Interval Operations, SAM calculate_contrast_threshold iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/calculate_contrast_threshold 1.0.0 numpy (0/1) (0/1) (0/1) True False +cat cat_add_names, cat_bins, cat_contigs, cat_prepare, cat_summarise Contig Annotation Tool (CAT) cat_bins CAT and BAT Contig Annotation Tool (CAT) and Bin Annotation Tool (BAT) are pipelines for the taxonomic classification of long DNA sequences and metagenome assembled genomes (MAGs/bins) of both known and (highly) unknown microorganisms, as generated by contemporary metagenomics studies. The core algorithm of both programs involves gene calling, mapping of predicted ORFs against the nr protein database, and voting-based classification of the entire contig / MAG based on classification of the individual ORFs. Taxonomic classification, Sequence assembly, Coding region prediction Metagenomics, Metagenomic sequencing, Taxonomy, Sequence assembly To update https://github.com/dutilh/CAT Metagenomics contig_annotation_tool iuc https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/cat 5.2.3 cat 5.3 (5/5) (2/5) (5/5) True True +cdhit 8278.0 6.0 cd_hit Cluster or compare biological sequence datasets cd-hit cd-hit Cluster a nucleotide dataset into representative sequences. Sequence clustering Sequencing Up-to-date http://weizhongli-lab.org/cd-hit/ Sequence Analysis, Fasta Manipulation cd_hit iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/cdhit 4.8.1 cd-hit 4.8.1 (0/1) (0/1) (1/1) True True +cemitool 98.0 9.0 cemitool Gene co-expression network analysis tool cemitool CEMiTool It unifies the discovery and the analysis of coexpression gene modules in a fully automatic manner, while providing a user-friendly html report with high quality graphs. Our tool evaluates if modules contain genes that are over-represented by specific pathways or that are altered in a specific sample group. Additionally, CEMiTool is able to integrate transcriptomic data with interactome information, identifying the potential hubs on each network. Enrichment analysis, Pathway or network analysis Gene expression, Transcriptomics, Microarray experiment To update https://www.bioconductor.org/packages/release/bioc/html/CEMiTool.html Transcriptomics, RNA, Statistics cemitool iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/cemitool 1.18.1 bioconductor-cemitool 1.26.0 (1/1) (0/1) (1/1) True True +charts 3589.0 287.0 charts Enables advanced visualization options in Galaxy Charts To update Visualization charts iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/charts/ 1.0.1 r-getopt (0/1) (0/1) (0/1) True False +checkm checkm_analyze, checkm_lineage_set, checkm_lineage_wf, checkm_plot, checkm_qa, checkm_taxon_set, checkm_taxonomy_wf, checkm_tetra, checkm_tree, checkm_tree_qa Assess the quality of microbial genomes recovered from isolates, single cells, and metagenomes checkm CheckM CheckM provides a set of tools for assessing the quality of genomes recovered from isolates, single cells, or metagenomes. Operation Genomics, Phylogenomics, Phylogenetics, Taxonomy, Metagenomics To update https://github.com/Ecogenomics/CheckM Metagenomics checkm iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/checkm 1.2.0 checkm-genome 1.2.2 (0/10) (0/10) (10/10) True True +cherri cherri_eval, cherri_train Computational Help Evaluating RNA-RNA interactions cherri cherri CheRRI detects functional RNA-RNA interaction (RRI) sites, by evaluating if an interaction site most likely occurs in nature. It helps to filter interaction sites generated either experimentally or by an RRI prediction algorithm by removing false positive interactions. Molecular interactions, pathways and networks, Structure analysis, Machine learning To update https://github.com/BackofenLab/Cherri Transcriptomics, RNA iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/cherri 0.7 cherri 0.8 (0/2) (0/2) (2/2) True False +chira 74.0 chira_collapse, chira_extract, chira_map, chira_merge, chira_quantify Chimeric Read Annotator for RNA-RNA interactome data chira ChiRA ChiRA is a tool suite to analyze RNA-RNA interactome experimental data such as CLASH, CLEAR-CLIP, PARIS, SPLASH, etc. RNA, Molecular interactions, pathways and networks, Functional, regulatory and non-coding RNA Up-to-date https://github.com/pavanvidem/chira RNA, Transcriptomics, Sequence Analysis chira iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/chira 1.4.3 chira 1.4.3 (5/5) (0/5) (5/5) True False +chromeister 2130.0 182.0 chromeister ultra-fast pairwise genome comparisons Up-to-date https://github.com/estebanpw/chromeister Sequence Analysis chromeister iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/chromeister 1.5.a chromeister 1.5.a (0/1) (1/1) (1/1) True False +circexplorer2 269.0 16.0 circexplorer2 Comprehensive and integrative circular RNA analysis toolset. circexplorer2 CIRCexplorer2 Genome-wide annotation of circRNAs and their alternative back-splicing/splicing. RNA splicing, Gene transcripts, Literature and language Up-to-date https://github.com/YangLab/CIRCexplorer2 RNA, Assembly circexplorer2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/circexplorer2 2.3.8 circexplorer2 2.3.8 (0/1) (0/1) (1/1) True False +clair3 1856.0 68.0 clair3 Symphonizing pileup and full-alignment for high-performance long-read variant calling clair3 Clair3 Clair3 is a germline small variant caller for long-reads. Clair3 makes the best of two major method categories: pileup calling handles most variant candidates with speed, and full-alignment tackles complicated candidates to maximize precision and recall. Clair3 runs fast and has superior performance, especially at lower coverage. Clair3 is simple and modular for easy deployment and integration. Variant calling Molecular genetics To update https://github.com/HKU-BAL/Clair3 Sequence Analysis, Variant Analysis clair3 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/clair3 0.1.12 clair3 1.0.5 (0/1) (0/1) (1/1) True False clustalw 46793.0 651.0 clustalw ClustalW multiple sequence alignment program for DNA or proteins " clustal2 - " Up-to-date http://www.clustal.org/clustal2/ Phylogenetics, Sequence Analysis clustalw devteam https://github.com/galaxyproject/tools-iuc/tree/master/tools/clustalw 2.1 clustalw 2.1 (1/1) (1/1) (1/1) True True -codeml 60901.0 29.0 codeml Detects positive selection paml PAML Package of programs for phylogenetic analyses of DNA or protein sequences using maximum likelihood. Probabilistic sequence generation, Phylogenetic tree generation (maximum likelihood and Bayesian methods), Phylogenetic tree analysis Phylogenetics, Sequence analysis To update http://abacus.gene.ucl.ac.uk/software/paml.html Phylogenetics codeml iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/codeml 4.9 paml 4.10.7 (0/1) (0/1) (1/1) True True -cojac cooc_mutbamscan, cooc_pubmut, cooc_tabmut co-occurrence of mutations on amplicons cojac COJAC CoOccurrence adJusted Analysis and Calling - The cojac package comprises a set of command-line tools to analyse co-occurrence of mutations on amplicons. It is useful, for example, for early detection of viral variants of concern (e.g. Alpha, Delta, Omicron) in environmental samples, and has been designed to scan for multiple SARS-CoV-2 variants in wastewater samples, as analyzed jointly by ETH Zurich, EPFL and Eawag. Genetic variation Up-to-date https://github.com/cbg-ethz/cojac Metagenomics, Sequence Analysis cojac iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/cojac 0.9.1 cojac 0.9.1 (2/3) (0/3) (3/3) True True -colibread commet, discosnp_rad, discosnp_pp, kissplice, lordec, mapsembler2, takeabreak Colib'read tools are all dedicated to the analysis of NGS datasets without the need of any reference genome To update https://colibread.inria.fr/ Sequence Analysis, Variant Analysis colibread iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/colibread 24.7.14+galaxy0 commet 24.7.14 (0/7) (0/7) (1/7) True False -compleasm compleasm Compleasm: a faster and more accurate reimplementation of BUSCO Up-to-date https://github.com/huangnengCSU/compleasm Sequence Analysis compleasm iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/compleasm/ 0.2.5 compleasm 0.2.5 (0/1) (0/1) (1/1) False -concoct 250.0 29.0 concoct, concoct_coverage_table, concoct_cut_up_fasta, concoct_extract_fasta_bins, concoct_merge_cut_up_clustering CONCOCT (Clustering cONtigs with COverage and ComposiTion) does unsupervised binning of metagenomic contigs byusing nucleotide composition - kmer frequencies - and coverage data for multiple samples. CONCOCT can accurately(up to species level) bin metagenomic contigs. concoct CONCOCT A program for unsupervised binning of metagenomic contigs by using nucleotide composition, coverage data in multiple samples and linkage data from paired end reads. Sequence clustering, Read binning Metagenomics Up-to-date https://github.com/BinPro/CONCOCT Metagenomics concoct iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/concoct 1.1.0 concoct 1.1.0 (0/5) (0/5) (5/5) True True -coverage_report CoverageReport2 Generate Detailed Coverage Report from BAM file To update https://github.com/galaxyproject/tools-iuc Sequence Analysis coverage_report iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/coverage_report 0.0.4 perl-number-format 1.76 (0/1) (0/1) (0/1) True False -coverm coverm_contig, coverm_genome CoverM genome and contig wrappers coverm CoverM Read coverage calculator for metagenomics Local alignment Bioinformatics Up-to-date https://github.com/wwood/CoverM Sequence Analysis coverm iuc https://github.com/galaxyproject/tools-iuc/tools/coverm 0.7.0 coverm 0.7.0 (0/2) (0/2) (2/2) True True -crispr_studio 636.0 30.0 crispr_studio CRISPR Studio is a program developed to facilitate and accelerate CRISPR array visualization. To update https://github.com/moineaulab/CRISPRStudio Sequence Analysis crispr_studio iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/crispr_studio/ 1+galaxy0 crispr_studio 1 (0/1) (0/1) (1/1) True False -crosscontamination_barcode_filter 347.0 17.0 crosscontamination_barcode_filter Barcode contamination discovery tool To update Transcriptomics, Visualization crosscontamination_barcode_filter iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/crosscontamination_barcode_filter 0.3 r-ggplot2 2.2.1 (1/1) (0/1) (1/1) True False -cutadapt 232004.0 5090.0 cutadapt Flexible tool to remove adapter sequences (and quality trim) high throughput sequencing reads (fasta/fastq). cutadapt Cutadapt Find and remove adapter sequences, primers, poly-A tails and other types of unwanted sequence from your high-throughput sequencing reads. Sequence trimming Genomics, Probes and primers, Sequencing Up-to-date https://cutadapt.readthedocs.org/en/stable/ Fasta Manipulation, Fastq Manipulation, Sequence Analysis cutadapt lparsons https://github.com/galaxyproject/tools-iuc/tree/master/tools/cutadapt 4.6 cutadapt 4.6 (1/1) (1/1) (1/1) True True -dada2 dada2_assignTaxonomyAddspecies, dada2_dada, dada2_filterAndTrim, dada2_learnErrors, dada2_makeSequenceTable, dada2_mergePairs, dada2_plotComplexity, dada2_plotQualityProfile, dada2_removeBimeraDenovo, dada2_seqCounts DADA2 wrappers dada2 dada2 This package infers exact sequence variants (SVs) from amplicon data, replacing the commonly used and coarser OTU clustering approach. This pipeline inputs demultiplexed fastq files, and outputs the sequence variants and their sample-wise abundances after removing substitution and chimera errors. Taxonomic classification is available via a native implementation of the RDP naive Bayesian classifier. Variant calling, DNA barcoding Sequencing, Genetic variation, Microbial ecology, Metagenomics To update https://benjjneb.github.io/dada2/index.html Metagenomics dada2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/dada2 bioconductor-dada2 1.30.0 (10/10) (10/10) (10/10) True True -das_tool 550.0 17.0 Fasta_to_Contig2Bin, das_tool DAS Tool for genome resolved metagenomics dastool dastool DAS Tool is an automated method that integrates the results of a flexible number of binning algorithms to calculate an optimized, non-redundant set of bins from a single assembly. Read binning Metagenomics Up-to-date https://github.com/cmks/DAS_Tool Metagenomics das_tool iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/das_tool 1.1.7 das_tool 1.1.7 (0/2) (0/2) (2/2) True True -deepsig 5.0 deepsig Predictor of signal peptides in proteins based on deep learning Up-to-date https://github.com/BolognaBiocomp/deepsig Genome annotation deepsig iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/deepsig 1.2.5 deepsig 1.2.5 (0/1) (0/1) (1/1) True False -deseq2 95752.0 4990.0 deseq2 Differential gene expression analysis based on the negative binomial distribution DESeq2 DESeq2 R/Bioconductor package for differential gene expression analysis based on the negative binomial distribution. Estimate variance-mean dependence in count data from high-throughput sequencing assays and test for differential expression based on a model using the negative binomial distribution. Differential gene expression analysis Transcriptomics To update https://www.bioconductor.org/packages/release/bioc/html/DESeq2.html Transcriptomics, RNA, Statistics deseq2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/deseq2 2.11.40.8 bioconductor-deseq2 1.42.0 (1/1) (1/1) (1/1) True False -dexseq 16064.0 218.0 dexseq, dexseq_count, plotdexseq Inference of differential exon usage in RNA-Seq dexseq DEXSeq The package is focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results. Enrichment analysis, Exonic splicing enhancer prediction RNA-Seq To update https://www.bioconductor.org/packages/release/bioc/html/DEXSeq.html Transcriptomics, RNA, Statistics dexseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/dexseq 1.44 bioconductor-dexseq 1.48.0 (3/3) (3/3) (3/3) True False -diamond 49711.0 963.0 bg_diamond, bg_diamond_makedb, bg_diamond_view DIAMOND is a new alignment tool for aligning short DNA sequencing reads to a protein reference database such as NCBI-NR. diamond Diamond Sequence aligner for protein and translated DNA searches and functions as a drop-in replacement for the NCBI BLAST software tools. It is suitable for protein-protein search as well as DNA-protein search on short reads and longer sequences including contigs and assemblies, providing a speedup of BLAST ranging up to x20,000. Sequence alignment analysis Sequence analysis, Proteins To update https://github.com/bbuchfink/diamond Sequence Analysis diamond bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/diamond 2.0.15 diamond 2.1.9 (3/3) (3/3) (3/3) True True -disco 369.0 42.0 disco DISCO is a overlap-layout-consensus (OLC) metagenome assembler disco DISCO DISCO is software to perform structure determination of protein homo-oligomers with cyclic symmetry.DISCO computes oligomeric protein structures using geometric constraints derived from RDCs and intermolecular distance restraints such as NOEs or disulfide bonds. When a reliable subunit structure can be calculated from intramolecular restraints, DISCO guarantees that all satisfying oligomer structures will be discovered, yet can run in minutes to hours on only a single desktop-class computer. Protein sequence analysis Structure determination To update http://disco.omicsbio.org/ Metagenomics, Assembly disco iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/disco/ disco 1.2 (1/1) (0/1) (1/1) True True -dram dram_annotate, dram_distill, dram_merge_annotations, dram_neighborhoods, dram_strainer DRAM for distilling microbial metabolism to automate the curation of microbiome function dram DRAM Distilled and Refined Annotation of Metabolism: A tool for the annotation and curation of function for microbial and viral genomes Gene functional annotation Metagenomics, Biological databases, Molecular genetics To update https://github.com/WrightonLabCSU/DRAM Metagenomics dram iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/dram 1.3.5 dram 1.4.6 (0/5) (0/5) (5/5) True True -drep drep_compare, drep_dereplicate dRep compares and dereplicates genome sets drep dRep Fast and accurate genomic comparisons that enables improved genome recovery from metagenomes through de-replication. Genome comparison Metagenomics, Genomics, Sequence analysis Up-to-date https://github.com/MrOlm/drep Metagenomics drep iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/drep 3.4.5 drep 3.4.5 (0/2) (0/2) (2/2) True True -dropletutils 3934.0 126.0 dropletutils DropletUtils - Utilities for handling droplet-based single-cell RNA-seq data dropletutils DropletUtils Provides a number of utility functions for handling single-cell (RNA-seq) data from droplet technologies such as 10X Genomics. This includes data loading, identification of cells from empty droplets, removal of barcode-swapped pseudo-cells, and downsampling of the count matrix. Loading, Community profiling Gene expression, RNA-seq, Sequencing, Transcriptomics To update https://bioconductor.org/packages/devel/bioc/html/DropletUtils.html Transcriptomics, Sequence Analysis dropletutils iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/dropletutils/ 1.10.0 bioconductor-dropletutils 1.22.0 (1/1) (1/1) (1/1) True False -edger 18522.0 945.0 edger Perform RNA-Seq differential expression analysis using edgeR pipeline edger edgeR Differential expression analysis of RNA-seq expression profiles with biological replication. Implements a range of statistical methodology based on the negative binomial distributions, including empirical Bayes estimation, exact tests, generalized linear models and quasi-likelihood tests. As well as RNA-seq, it be applied to differential signal analysis of other types of genomic data that produce counts, including ChIP-seq, SAGE and CAGE. Differential gene expression analysis Genetics, RNA-Seq, ChIP-seq To update http://bioconductor.org/packages/release/bioc/html/edgeR.html Transcriptomics, RNA, Statistics edger iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/edger 3.36.0 bioconductor-edger 4.0.2 (1/1) (1/1) (1/1) True False -egsea 2524.0 177.0 egsea This tool implements the Ensemble of Gene Set Enrichment Analyses (EGSEA) method for gene set testing egsea EGSEA This package implements the Ensemble of Gene Set Enrichment Analyses method for gene set testing. Gene set testing Systems biology To update https://bioconductor.org/packages/release/bioc/html/EGSEA.html Transcriptomics, RNA, Statistics egsea iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/egsea 1.20.0 bioconductor-egsea 1.28.0 (1/1) (1/1) (1/1) True False -emboss_5 89530.0 1816.0 EMBOSS: antigenic1, EMBOSS: backtranseq2, EMBOSS: banana3, EMBOSS: biosed4, EMBOSS: btwisted5, EMBOSS: cai6, EMBOSS: cai_custom6, EMBOSS: chaos7, EMBOSS: charge8, EMBOSS: checktrans9, EMBOSS: chips10, EMBOSS: cirdna11, EMBOSS: codcmp12, EMBOSS: coderet13, EMBOSS: compseq14, EMBOSS: cpgplot15, EMBOSS: cpgreport16, EMBOSS: cusp17, EMBOSS: cutseq18, EMBOSS: dan19, EMBOSS: degapseq20, EMBOSS: descseq21, EMBOSS: diffseq22, EMBOSS: digest23, EMBOSS: dotmatcher24, EMBOSS: dotpath25, EMBOSS: dottup26, EMBOSS: dreg27, EMBOSS: einverted28, EMBOSS: epestfind29, EMBOSS: equicktandem31, EMBOSS: est2genome32, EMBOSS: etandem33, EMBOSS: extractfeat34, EMBOSS: extractseq35, EMBOSS: freak36, EMBOSS: fuzznuc37, EMBOSS: fuzzpro38, EMBOSS: fuzztran39, EMBOSS: garnier40, EMBOSS: geecee41, EMBOSS: getorf42, EMBOSS: helixturnhelix43, EMBOSS: hmoment44, EMBOSS: iep45, EMBOSS: infoseq46, EMBOSS: isochore47, EMBOSS: lindna48, EMBOSS: marscan49, EMBOSS: maskfeat50, EMBOSS: maskseq51, EMBOSS: matcher52, EMBOSS: megamerger53, EMBOSS: merger54, EMBOSS: msbar55, EMBOSS: needle56, EMBOSS: newcpgreport57, EMBOSS: newcpgseek58, EMBOSS: newseq59, EMBOSS: noreturn60, EMBOSS: notseq61, EMBOSS: nthseq62, EMBOSS: octanol63, EMBOSS: oddcomp64, EMBOSS: palindrome65, EMBOSS: pasteseq66, EMBOSS: patmatdb67, EMBOSS: pepcoil68, EMBOSS: pepinfo69, EMBOSS: pepnet70, EMBOSS: pepstats71, EMBOSS: pepwheel72, EMBOSS: pepwindow73, EMBOSS: pepwindowall74, EMBOSS: plotcon75, EMBOSS: plotorf76, EMBOSS: polydot77, EMBOSS: preg78, EMBOSS: prettyplot79, EMBOSS: prettyseq80, EMBOSS: primersearch81, EMBOSS: revseq82, EMBOSS: seqmatchall83, EMBOSS: seqret84, EMBOSS: showfeat85, EMBOSS: shuffleseq87, EMBOSS: sigcleave88, EMBOSS: sirna89, EMBOSS: sixpack90, EMBOSS: skipseq91, EMBOSS: splitter92, EMBOSS: supermatcher95, EMBOSS: syco96, EMBOSS: tcode97, EMBOSS: textsearch98, EMBOSS: tmap99, EMBOSS: tranalign100, EMBOSS: transeq101, EMBOSS: trimest102, EMBOSS: trimseq103, EMBOSS: twofeat104, EMBOSS: union105, EMBOSS: vectorstrip106, EMBOSS: water107, EMBOSS: wobble108, EMBOSS: wordcount109, EMBOSS: wordmatch110 Galaxy wrappers for EMBOSS version 5.0.0 tools emboss EMBOSS Diverse suite of tools for sequence analysis; many programs analagous to GCG; context-sensitive help for each tool. Sequence analysis, Local alignment, Sequence alignment analysis, Global alignment, Sequence alignment Molecular biology, Sequence analysis, Biology To update http://emboss.open-bio.org/ Sequence Analysis, Fasta Manipulation emboss_5 devteam https://github.com/galaxyproject/tools-iuc/tree/master/tools/emboss_5 5.0.0 emboss 6.6.0 (107/107) (107/107) (107/107) True False -exomedepth 410.0 29.0 exomedepth ExomeDepth: Calls copy number variants (CNVs) from targeted sequence data exomedepth ExomeDepth Copy number variant (CNV) calling algorithm designed to control technical variability between samples. It calls CNVs from targeted sequence data, typically exome sequencing experiments designed to identify the genetic basis of Mendelian disorders. Sequence analysis, Variant calling, Genotyping, Copy number estimation Exome sequencing, Gene transcripts, Mapping, Sequencing, Genetic variation, Rare diseases To update https://cran.r-project.org/package=ExomeDepth Sequence Analysis, Variant Analysis exomedepth crs4 https://github.com/galaxyproject/tools-iuc/tree/master/tools/exomedepth 1.1.0 r-exomedepth 1.1.16 (1/1) (0/1) (1/1) True False -exonerate 988.0 59.0 exonerate Exonerate is a generic tool for pairwise sequence comparison. exonerate Exonerate A tool for pairwise sequence alignment. It enables alignment for DNA-DNA and DNA-protein pairs and also gapped and ungapped alignment. Pairwise sequence alignment, Protein threading, Genome alignment Sequence analysis, Sequence sites, features and motifs, Molecular interactions, pathways and networks Up-to-date https://www.ebi.ac.uk/about/vertebrate-genomics/software/exonerate Sequence Analysis exonerate iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/exonerate 2.4.0 exonerate 2.4.0 (1/1) (1/1) (1/1) True False -export2graphlan 5265.0 200.0 export2graphlan export2graphlan is a conversion software tool for producing both annotation and tree file for GraPhlAn export2graphlan export2graphlan export2graphlan is a conversion software tool for producing both annotation and tree file for GraPhlAn. In particular, the annotation file tries to highlight specific sub-trees deriving automatically from input file what nodes are important. Conversion Taxonomy, Metabolomics, Biomarkers To update https://bitbucket.org/CibioCM/export2graphlan/overview Metagenomics export2graphlan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/export2graphlan/ 0.20 export2graphlan 0.22 (1/1) (1/1) (1/1) True True -fargene 459.0 52.0 fargene fARGene (Fragmented Antibiotic Resistance Gene iENntifiEr ) fargene fARGene fARGene (Fragmented Antibiotic Resistance Gene iENntifiEr ) is a tool that takes either fragmented metagenomic data or longer sequences as input and predicts and delivers full-length antiobiotic resistance genes as output. Antimicrobial resistance prediction Metagenomics, Microbiology, Public health and epidemiology Up-to-date https://github.com/fannyhb/fargene Sequence Analysis fargene iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/fargene 0.1 fargene 0.1 (1/1) (0/1) (1/1) True True -fasta_nucleotide_color_plot 322.0 39.0 fasta_nucleotide_color_plot Contains a tool that produces a graphical representation of FASTA data with each nucleotide represented by a selected color. To update https://github.com/seqcode/cegr-tools/tree/master/src/org/seqcode/cegrtools/fourcolorplot Visualization fasta_nucleotide_color_plot iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/fasta_nucleotide_color_plot 1.0.1 openjdk (1/1) (0/1) (1/1) True False -fasta_stats 35332.0 1080.0 fasta-stats Display summary statistics for a fasta file. To update https://github.com/galaxyproject/tools-iuc/tree/master/tools/fasta_stats/ Sequence Analysis fasta_stats iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/fasta_stats/ 2.0 numpy (1/1) (1/1) (1/1) True False -fastani 3498.0 250.0 fastani Fast alignment-free computation of whole-genome Average Nucleotide Identity To update https://github.com/ParBLiSS/FastANI Sequence Analysis fastani iuc 1.3 fastani 1.34 (0/1) (0/1) (1/1) True False + " Up-to-date http://www.clustal.org/clustal2/ Phylogenetics, Sequence Analysis clustalw devteam https://github.com/galaxyproject/tools-iuc/tree/master/tools/clustalw 2.1 clustalw 2.1 (1/1) (1/1) (1/1) True True +codeml 60901.0 29.0 codeml Detects positive selection paml PAML Package of programs for phylogenetic analyses of DNA or protein sequences using maximum likelihood. Probabilistic sequence generation, Phylogenetic tree generation (maximum likelihood and Bayesian methods), Phylogenetic tree analysis Phylogenetics, Sequence analysis To update http://abacus.gene.ucl.ac.uk/software/paml.html Phylogenetics codeml iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/codeml 4.9 paml 4.10.7 (0/1) (0/1) (1/1) True True +cojac cooc_mutbamscan, cooc_pubmut, cooc_tabmut co-occurrence of mutations on amplicons cojac COJAC CoOccurrence adJusted Analysis and Calling - The cojac package comprises a set of command-line tools to analyse co-occurrence of mutations on amplicons. It is useful, for example, for early detection of viral variants of concern (e.g. Alpha, Delta, Omicron) in environmental samples, and has been designed to scan for multiple SARS-CoV-2 variants in wastewater samples, as analyzed jointly by ETH Zurich, EPFL and Eawag. Genetic variation Up-to-date https://github.com/cbg-ethz/cojac Metagenomics, Sequence Analysis cojac iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/cojac 0.9.1 cojac 0.9.1 (2/3) (0/3) (3/3) True True +colibread commet, discosnp_rad, discosnp_pp, kissplice, lordec, mapsembler2, takeabreak Colib'read tools are all dedicated to the analysis of NGS datasets without the need of any reference genome To update https://colibread.inria.fr/ Sequence Analysis, Variant Analysis colibread iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/colibread 24.7.14+galaxy0 commet 24.7.14 (0/7) (0/7) (1/7) True False +compleasm compleasm Compleasm: a faster and more accurate reimplementation of BUSCO Up-to-date https://github.com/huangnengCSU/compleasm Sequence Analysis compleasm iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/compleasm/ 0.2.5 compleasm 0.2.5 (0/1) (0/1) (1/1) False +concoct 250.0 29.0 concoct, concoct_coverage_table, concoct_cut_up_fasta, concoct_extract_fasta_bins, concoct_merge_cut_up_clustering CONCOCT (Clustering cONtigs with COverage and ComposiTion) does unsupervised binning of metagenomic contigs byusing nucleotide composition - kmer frequencies - and coverage data for multiple samples. CONCOCT can accurately(up to species level) bin metagenomic contigs. concoct CONCOCT A program for unsupervised binning of metagenomic contigs by using nucleotide composition, coverage data in multiple samples and linkage data from paired end reads. Sequence clustering, Read binning Metagenomics Up-to-date https://github.com/BinPro/CONCOCT Metagenomics concoct iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/concoct 1.1.0 concoct 1.1.0 (0/5) (0/5) (5/5) True True +coverage_report CoverageReport2 Generate Detailed Coverage Report from BAM file To update https://github.com/galaxyproject/tools-iuc Sequence Analysis coverage_report iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/coverage_report 0.0.4 perl-number-format 1.76 (0/1) (0/1) (0/1) True False +coverm coverm_contig, coverm_genome CoverM genome and contig wrappers coverm CoverM Read coverage calculator for metagenomics Local alignment Bioinformatics Up-to-date https://github.com/wwood/CoverM Sequence Analysis coverm iuc https://github.com/galaxyproject/tools-iuc/tools/coverm 0.7.0 coverm 0.7.0 (0/2) (0/2) (2/2) True True +crispr_studio 636.0 30.0 crispr_studio CRISPR Studio is a program developed to facilitate and accelerate CRISPR array visualization. To update https://github.com/moineaulab/CRISPRStudio Sequence Analysis crispr_studio iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/crispr_studio/ 1+galaxy0 crispr_studio 1 (0/1) (0/1) (1/1) True False +crosscontamination_barcode_filter 347.0 17.0 crosscontamination_barcode_filter Barcode contamination discovery tool To update Transcriptomics, Visualization crosscontamination_barcode_filter iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/crosscontamination_barcode_filter 0.3 r-ggplot2 2.2.1 (1/1) (0/1) (1/1) True False +cutadapt 232004.0 5090.0 cutadapt Flexible tool to remove adapter sequences (and quality trim) high throughput sequencing reads (fasta/fastq). cutadapt Cutadapt Find and remove adapter sequences, primers, poly-A tails and other types of unwanted sequence from your high-throughput sequencing reads. Sequence trimming Genomics, Probes and primers, Sequencing Up-to-date https://cutadapt.readthedocs.org/en/stable/ Fasta Manipulation, Fastq Manipulation, Sequence Analysis cutadapt lparsons https://github.com/galaxyproject/tools-iuc/tree/master/tools/cutadapt 4.6 cutadapt 4.6 (1/1) (1/1) (1/1) True True +dada2 dada2_assignTaxonomyAddspecies, dada2_dada, dada2_filterAndTrim, dada2_learnErrors, dada2_makeSequenceTable, dada2_mergePairs, dada2_plotComplexity, dada2_plotQualityProfile, dada2_removeBimeraDenovo, dada2_seqCounts DADA2 wrappers dada2 dada2 This package infers exact sequence variants (SVs) from amplicon data, replacing the commonly used and coarser OTU clustering approach. This pipeline inputs demultiplexed fastq files, and outputs the sequence variants and their sample-wise abundances after removing substitution and chimera errors. Taxonomic classification is available via a native implementation of the RDP naive Bayesian classifier. Variant calling, DNA barcoding Sequencing, Genetic variation, Microbial ecology, Metagenomics To update https://benjjneb.github.io/dada2/index.html Metagenomics dada2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/dada2 bioconductor-dada2 1.30.0 (10/10) (10/10) (10/10) True True +das_tool 550.0 17.0 Fasta_to_Contig2Bin, das_tool DAS Tool for genome resolved metagenomics dastool dastool DAS Tool is an automated method that integrates the results of a flexible number of binning algorithms to calculate an optimized, non-redundant set of bins from a single assembly. Read binning Metagenomics Up-to-date https://github.com/cmks/DAS_Tool Metagenomics das_tool iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/das_tool 1.1.7 das_tool 1.1.7 (0/2) (0/2) (2/2) True True +deepsig 5.0 deepsig Predictor of signal peptides in proteins based on deep learning Up-to-date https://github.com/BolognaBiocomp/deepsig Genome annotation deepsig iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/deepsig 1.2.5 deepsig 1.2.5 (0/1) (0/1) (1/1) True False +deseq2 95752.0 4990.0 deseq2 Differential gene expression analysis based on the negative binomial distribution DESeq2 DESeq2 R/Bioconductor package for differential gene expression analysis based on the negative binomial distribution. Estimate variance-mean dependence in count data from high-throughput sequencing assays and test for differential expression based on a model using the negative binomial distribution. Differential gene expression analysis Transcriptomics To update https://www.bioconductor.org/packages/release/bioc/html/DESeq2.html Transcriptomics, RNA, Statistics deseq2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/deseq2 2.11.40.8 bioconductor-deseq2 1.42.0 (1/1) (1/1) (1/1) True False +dexseq 16064.0 218.0 dexseq, dexseq_count, plotdexseq Inference of differential exon usage in RNA-Seq dexseq DEXSeq The package is focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results. Enrichment analysis, Exonic splicing enhancer prediction RNA-Seq To update https://www.bioconductor.org/packages/release/bioc/html/DEXSeq.html Transcriptomics, RNA, Statistics dexseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/dexseq 1.44 bioconductor-dexseq 1.48.0 (3/3) (3/3) (3/3) True False +diamond 49711.0 963.0 bg_diamond, bg_diamond_makedb, bg_diamond_view DIAMOND is a new alignment tool for aligning short DNA sequencing reads to a protein reference database such as NCBI-NR. diamond Diamond Sequence aligner for protein and translated DNA searches and functions as a drop-in replacement for the NCBI BLAST software tools. It is suitable for protein-protein search as well as DNA-protein search on short reads and longer sequences including contigs and assemblies, providing a speedup of BLAST ranging up to x20,000. Sequence alignment analysis Sequence analysis, Proteins To update https://github.com/bbuchfink/diamond Sequence Analysis diamond bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/diamond 2.0.15 diamond 2.1.9 (3/3) (3/3) (3/3) True True +disco 369.0 42.0 disco DISCO is a overlap-layout-consensus (OLC) metagenome assembler disco DISCO DISCO is software to perform structure determination of protein homo-oligomers with cyclic symmetry.DISCO computes oligomeric protein structures using geometric constraints derived from RDCs and intermolecular distance restraints such as NOEs or disulfide bonds. When a reliable subunit structure can be calculated from intramolecular restraints, DISCO guarantees that all satisfying oligomer structures will be discovered, yet can run in minutes to hours on only a single desktop-class computer. Protein sequence analysis Structure determination To update http://disco.omicsbio.org/ Metagenomics, Assembly disco iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/disco/ disco 1.2 (1/1) (0/1) (1/1) True True +dram dram_annotate, dram_distill, dram_merge_annotations, dram_neighborhoods, dram_strainer DRAM for distilling microbial metabolism to automate the curation of microbiome function dram DRAM Distilled and Refined Annotation of Metabolism: A tool for the annotation and curation of function for microbial and viral genomes Gene functional annotation Metagenomics, Biological databases, Molecular genetics To update https://github.com/WrightonLabCSU/DRAM Metagenomics dram iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/dram 1.3.5 dram 1.4.6 (0/5) (0/5) (5/5) True True +drep drep_compare, drep_dereplicate dRep compares and dereplicates genome sets drep dRep Fast and accurate genomic comparisons that enables improved genome recovery from metagenomes through de-replication. Genome comparison Metagenomics, Genomics, Sequence analysis Up-to-date https://github.com/MrOlm/drep Metagenomics drep iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/drep 3.4.5 drep 3.4.5 (0/2) (0/2) (2/2) True True +dropletutils 3934.0 126.0 dropletutils DropletUtils - Utilities for handling droplet-based single-cell RNA-seq data dropletutils DropletUtils Provides a number of utility functions for handling single-cell (RNA-seq) data from droplet technologies such as 10X Genomics. This includes data loading, identification of cells from empty droplets, removal of barcode-swapped pseudo-cells, and downsampling of the count matrix. Loading, Community profiling Gene expression, RNA-seq, Sequencing, Transcriptomics To update https://bioconductor.org/packages/devel/bioc/html/DropletUtils.html Transcriptomics, Sequence Analysis dropletutils iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/dropletutils/ 1.10.0 bioconductor-dropletutils 1.22.0 (1/1) (1/1) (1/1) True False +edger 18522.0 945.0 edger Perform RNA-Seq differential expression analysis using edgeR pipeline edger edgeR Differential expression analysis of RNA-seq expression profiles with biological replication. Implements a range of statistical methodology based on the negative binomial distributions, including empirical Bayes estimation, exact tests, generalized linear models and quasi-likelihood tests. As well as RNA-seq, it be applied to differential signal analysis of other types of genomic data that produce counts, including ChIP-seq, SAGE and CAGE. Differential gene expression analysis Genetics, RNA-Seq, ChIP-seq To update http://bioconductor.org/packages/release/bioc/html/edgeR.html Transcriptomics, RNA, Statistics edger iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/edger 3.36.0 bioconductor-edger 4.0.2 (1/1) (1/1) (1/1) True False +egsea 2524.0 177.0 egsea This tool implements the Ensemble of Gene Set Enrichment Analyses (EGSEA) method for gene set testing egsea EGSEA This package implements the Ensemble of Gene Set Enrichment Analyses method for gene set testing. Gene set testing Systems biology To update https://bioconductor.org/packages/release/bioc/html/EGSEA.html Transcriptomics, RNA, Statistics egsea iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/egsea 1.20.0 bioconductor-egsea 1.28.0 (1/1) (1/1) (1/1) True False +emboss_5 89530.0 1816.0 EMBOSS: antigenic1, EMBOSS: backtranseq2, EMBOSS: banana3, EMBOSS: biosed4, EMBOSS: btwisted5, EMBOSS: cai6, EMBOSS: cai_custom6, EMBOSS: chaos7, EMBOSS: charge8, EMBOSS: checktrans9, EMBOSS: chips10, EMBOSS: cirdna11, EMBOSS: codcmp12, EMBOSS: coderet13, EMBOSS: compseq14, EMBOSS: cpgplot15, EMBOSS: cpgreport16, EMBOSS: cusp17, EMBOSS: cutseq18, EMBOSS: dan19, EMBOSS: degapseq20, EMBOSS: descseq21, EMBOSS: diffseq22, EMBOSS: digest23, EMBOSS: dotmatcher24, EMBOSS: dotpath25, EMBOSS: dottup26, EMBOSS: dreg27, EMBOSS: einverted28, EMBOSS: epestfind29, EMBOSS: equicktandem31, EMBOSS: est2genome32, EMBOSS: etandem33, EMBOSS: extractfeat34, EMBOSS: extractseq35, EMBOSS: freak36, EMBOSS: fuzznuc37, EMBOSS: fuzzpro38, EMBOSS: fuzztran39, EMBOSS: garnier40, EMBOSS: geecee41, EMBOSS: getorf42, EMBOSS: helixturnhelix43, EMBOSS: hmoment44, EMBOSS: iep45, EMBOSS: infoseq46, EMBOSS: isochore47, EMBOSS: lindna48, EMBOSS: marscan49, EMBOSS: maskfeat50, EMBOSS: maskseq51, EMBOSS: matcher52, EMBOSS: megamerger53, EMBOSS: merger54, EMBOSS: msbar55, EMBOSS: needle56, EMBOSS: newcpgreport57, EMBOSS: newcpgseek58, EMBOSS: newseq59, EMBOSS: noreturn60, EMBOSS: notseq61, EMBOSS: nthseq62, EMBOSS: octanol63, EMBOSS: oddcomp64, EMBOSS: palindrome65, EMBOSS: pasteseq66, EMBOSS: patmatdb67, EMBOSS: pepcoil68, EMBOSS: pepinfo69, EMBOSS: pepnet70, EMBOSS: pepstats71, EMBOSS: pepwheel72, EMBOSS: pepwindow73, EMBOSS: pepwindowall74, EMBOSS: plotcon75, EMBOSS: plotorf76, EMBOSS: polydot77, EMBOSS: preg78, EMBOSS: prettyplot79, EMBOSS: prettyseq80, EMBOSS: primersearch81, EMBOSS: revseq82, EMBOSS: seqmatchall83, EMBOSS: seqret84, EMBOSS: showfeat85, EMBOSS: shuffleseq87, EMBOSS: sigcleave88, EMBOSS: sirna89, EMBOSS: sixpack90, EMBOSS: skipseq91, EMBOSS: splitter92, EMBOSS: supermatcher95, EMBOSS: syco96, EMBOSS: tcode97, EMBOSS: textsearch98, EMBOSS: tmap99, EMBOSS: tranalign100, EMBOSS: transeq101, EMBOSS: trimest102, EMBOSS: trimseq103, EMBOSS: twofeat104, EMBOSS: union105, EMBOSS: vectorstrip106, EMBOSS: water107, EMBOSS: wobble108, EMBOSS: wordcount109, EMBOSS: wordmatch110 Galaxy wrappers for EMBOSS version 5.0.0 tools emboss EMBOSS Diverse suite of tools for sequence analysis; many programs analagous to GCG; context-sensitive help for each tool. Sequence analysis, Local alignment, Sequence alignment analysis, Global alignment, Sequence alignment Molecular biology, Sequence analysis, Biology To update http://emboss.open-bio.org/ Sequence Analysis, Fasta Manipulation emboss_5 devteam https://github.com/galaxyproject/tools-iuc/tree/master/tools/emboss_5 5.0.0 emboss 6.6.0 (107/107) (107/107) (107/107) True False +exomedepth 410.0 29.0 exomedepth ExomeDepth: Calls copy number variants (CNVs) from targeted sequence data exomedepth ExomeDepth Copy number variant (CNV) calling algorithm designed to control technical variability between samples. It calls CNVs from targeted sequence data, typically exome sequencing experiments designed to identify the genetic basis of Mendelian disorders. Sequence analysis, Variant calling, Genotyping, Copy number estimation Exome sequencing, Gene transcripts, Mapping, Sequencing, Genetic variation, Rare diseases To update https://cran.r-project.org/package=ExomeDepth Sequence Analysis, Variant Analysis exomedepth crs4 https://github.com/galaxyproject/tools-iuc/tree/master/tools/exomedepth 1.1.0 r-exomedepth 1.1.16 (1/1) (0/1) (1/1) True False +exonerate 988.0 59.0 exonerate Exonerate is a generic tool for pairwise sequence comparison. exonerate Exonerate A tool for pairwise sequence alignment. It enables alignment for DNA-DNA and DNA-protein pairs and also gapped and ungapped alignment. Pairwise sequence alignment, Protein threading, Genome alignment Sequence analysis, Sequence sites, features and motifs, Molecular interactions, pathways and networks Up-to-date https://www.ebi.ac.uk/about/vertebrate-genomics/software/exonerate Sequence Analysis exonerate iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/exonerate 2.4.0 exonerate 2.4.0 (1/1) (1/1) (1/1) True False +export2graphlan 5265.0 200.0 export2graphlan export2graphlan is a conversion software tool for producing both annotation and tree file for GraPhlAn export2graphlan export2graphlan export2graphlan is a conversion software tool for producing both annotation and tree file for GraPhlAn. In particular, the annotation file tries to highlight specific sub-trees deriving automatically from input file what nodes are important. Conversion Taxonomy, Metabolomics, Biomarkers To update https://bitbucket.org/CibioCM/export2graphlan/overview Metagenomics export2graphlan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/export2graphlan/ 0.20 export2graphlan 0.22 (1/1) (1/1) (1/1) True True +fargene 459.0 52.0 fargene fARGene (Fragmented Antibiotic Resistance Gene iENntifiEr ) fargene fARGene fARGene (Fragmented Antibiotic Resistance Gene iENntifiEr ) is a tool that takes either fragmented metagenomic data or longer sequences as input and predicts and delivers full-length antiobiotic resistance genes as output. Antimicrobial resistance prediction Metagenomics, Microbiology, Public health and epidemiology Up-to-date https://github.com/fannyhb/fargene Sequence Analysis fargene iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/fargene 0.1 fargene 0.1 (1/1) (0/1) (1/1) True True +fasta_nucleotide_color_plot 322.0 39.0 fasta_nucleotide_color_plot Contains a tool that produces a graphical representation of FASTA data with each nucleotide represented by a selected color. To update https://github.com/seqcode/cegr-tools/tree/master/src/org/seqcode/cegrtools/fourcolorplot Visualization fasta_nucleotide_color_plot iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/fasta_nucleotide_color_plot 1.0.1 openjdk (1/1) (0/1) (1/1) True False +fasta_stats 35332.0 1080.0 fasta-stats Display summary statistics for a fasta file. To update https://github.com/galaxyproject/tools-iuc/tree/master/tools/fasta_stats/ Sequence Analysis fasta_stats iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/fasta_stats/ 2.0 numpy (1/1) (1/1) (1/1) True False +fastani 3498.0 250.0 fastani Fast alignment-free computation of whole-genome Average Nucleotide Identity To update https://github.com/ParBLiSS/FastANI Sequence Analysis fastani iuc 1.3 fastani 1.34 (0/1) (0/1) (1/1) True False fastp 1055760.0 2803.0 fastp Fast all-in-one preprocessing for FASTQ files " fastp " To update https://github.com/OpenGene/fastp Sequence Analysis fastp iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/fastp fastp 0.23.4 (1/1) (1/1) (1/1) True True @@ -352,407 +352,407 @@ fraggenescan 1102.0 68.0 fraggenescan Tool for finding (fragmented) genes in sho freyja freyja_aggregate_plot, freyja_boot, freyja_demix, freyja_variants lineage abundances estimation freyja To update https://github.com/andersen-lab/Freyja Metagenomics, Sequence Analysis freyja iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/freyja 1.4.4 freyja 1.4.9 (2/4) (0/4) (4/4) True True funannotate funannotate_annotate, funannotate_clean, funannotate_compare, funannotate_predict, funannotate_sort Funannotate is a genome prediction, annotation, and comparison software package. " funannotate - " To update https://funannotate.readthedocs.io Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/funannotate 1.8.15 (3/5) (5/5) (5/5) True True -gecko 519.0 112.0 gecko Ungapped genome comparison Up-to-date https://github.com/otorreno/gecko Sequence Analysis gecko iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gecko 1.2 gecko 1.2 (0/1) (1/1) (1/1) True False -gemini 1209.0 gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_db_info, gemini_@BINARY@, gemini_@BINARY@, gemini_inheritance, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@ GEMINI: a flexible framework for exploring genome variation gemini GEMINI GEMINI (GEnome MINIng) is a flexible framework for exploring genetic variation in the context of the wealth of genome annotations available for the human genome. By placing genetic variants, sample phenotypes and genotypes, as well as genome annotations into an integrated database framework, GEMINI provides a simple, flexible, and powerful system for exploring genetic variation for disease and population genetics. Sequence analysis, Genetic variation analysis Sequence analysis To update https://github.com/arq5x/gemini Sequence Analysis, Next Gen Mappers gemini iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gemini 0.20.1 gemini 0.30.2 (1/3) (2/3) (2/3) True False -geneiobio 44.0 3.0 gene_iobio_display_generation_iframe Gene.iobio is an interactive tool for variant and trio analysis. To update https://github.com/iobio/gene.iobio Sequence Analysis geneiobio iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/geneiobio 4.7.1+galaxy1 (0/1) (1/1) (1/1) True False -genomic_super_signature 46.0 11.0 genomic_super_signature Interpretation of RNAseq experiments through robust, efficient comparison to public databases genomicsupersignature GenomicSuperSignature GenomicSuperSignature is a package for the interpretation of RNA-seq experiments through robust, efficient comparison to public databases. Gene-set enrichment analysis, Essential dynamics, Deposition, Principal component visualisation, Dimensionality reduction RNA-Seq, Transcriptomics, Microbial ecology, Genotype and phenotype, Microarray experiment To update https://github.com/shbrief/GenomicSuperSignature Sequence Analysis, RNA, Transcriptomics genomic_super_signature iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/genomic_super_signature 1.2.0 bioconductor-genomicsupersignature 1.10.0 (0/1) (0/1) (1/1) True False -getorganelle 495.0 18.0 get_annotated_regions_from_gb, get_organelle_from_reads GetOrganelle - This toolkit assembles organelle genomes from genomic skimming data. getorganelle GetOrganelle A fast and versatile toolkit for accurate de novo assembly of organelle genomes.This toolkit assemblies organelle genome from genomic skimming data. De-novo assembly, Genome assembly, Mapping assembly, Mapping, Sequence trimming Cell biology, Sequence assembly, Whole genome sequencing, Plant biology, Model organisms Up-to-date https://github.com/Kinggerm/GetOrganelle Assembly getorganelle iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/getorganelle 1.7.7.0 getorganelle 1.7.7.0 (0/2) (2/2) (2/2) True False -gff3_rebase 110.0 12.0 gff3.rebase Rebase a GFF against a parent GFF (e.g. an original genome) To update https://github.com/galaxyproject/tools-iuc/tree/master/tools/gff3_rebase Sequence Analysis gff3_rebase iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gff3_rebase 1.2 bcbiogff 0.6.6 (1/1) (1/1) (1/1) True False -gffread 10995.0 680.0 gffread gffread filters and/or converts GFF3/GTF2 records gffread gffread program for filtering, converting and manipulating GFF files Sequence annotation Nucleic acids, Sequence analysis Up-to-date http://ccb.jhu.edu/software/stringtie/gff.shtml#gffread/ Sequence Analysis gffread devteam https://github.com/galaxyproject/tools-iuc/tree/master/tools/gffread 0.12.7 gffread 0.12.7 (1/1) (1/1) (1/1) True False -ggplot2 ggplot2_heatmap, ggplot2_pca, ggplot2_histogram, ggplot2_point, ggplot2_violin ggplot2 is a system for declaratively creating graphics, based on The Grammar of Graphics.You provide the data, tell ggplot2 how to map variables to aesthetics, what graphical primitives to use,and it takes care of the details. ggplot2 ggplot2 Plotting system for R, based on the grammar of graphics. Visualisation Data visualisation To update https://github.com/tidyverse/ggplot2 Visualization iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ggplot2 3.4.0 r-base (5/5) (5/5) (5/5) True False -glimmer glimmer_acgt_content, glimmer_build_icm, glimmer_extract, glimmer_gbk_to_orf, glimmer_glimmer_to_gff, glimmer_long_orfs, glimmer_knowledge_based, glimmer_not_knowledge_based Glimmer makes gene predictions. gemini GEMINI GEMINI (GEnome MINIng) is a flexible framework for exploring genetic variation in the context of the wealth of genome annotations available for the human genome. By placing genetic variants, sample phenotypes and genotypes, as well as genome annotations into an integrated database framework, GEMINI provides a simple, flexible, and powerful system for exploring genetic variation for disease and population genetics. Sequence analysis, Genetic variation analysis Sequence analysis To update https://ccb.jhu.edu/software/glimmer/ Sequence Analysis bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/glimmer glimmer 3.02 (0/8) (0/8) (4/8) True True -goenrichment 5206.0 321.0 goenrichment, goslimmer Performs GO Enrichment analysis. goenrichment GOEnrichment GOEnrichment is a tool for performing GO enrichment analysis of gene sets, such as those obtained from RNA-seq or Microarray experiments, to help characterize them at the functional level. It is available in Galaxy Europe and as a stand-alone tool.GOEnrichment is flexible in that it allows the user to use any version of the Gene Ontology and any GO annotation file they desire. To enable the use of GO slims, it is accompanied by a sister tool GOSlimmer, which can convert annotation files from full GO to any specified GO slim.The tool features an optional graph clustering algorithm to reduce the redundancy in the set of enriched GO terms and simplify its output.It was developed by the BioData.pt / ELIXIR-PT team at the Instituto Gulbenkian de Ciência. Gene-set enrichment analysis Transcriptomics Up-to-date https://github.com/DanFaria/GOEnrichment Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/goenrichment 2.0.1 goenrichment 2.0.1 (2/2) (2/2) (2/2) True True -goseq 19167.0 1210.0 goseq goseq does selection-unbiased testing for category enrichment amongst differentially expressed (DE) genes for RNA-seq data goseq GOseq Detect Gene Ontology and/or other user defined categories which are over/under represented in RNA-seq data. Gene functional annotation RNA-Seq To update https://bioconductor.org/packages/release/bioc/html/goseq.html Statistics, RNA, Micro-array Analysis goseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/goseq 1.50.0 bioconductor-goseq 1.54.0 (1/1) (1/1) (1/1) True True -graphlan 5002.0 247.0 graphlan, graphlan_annotate GraPhlAn is a software tool for producing high-quality circular representations of taxonomic and phylogenetic trees graphlan GraPhlAn GraPhlAn is a software tool for producing high-quality circular representations of taxonomic and phylogenetic trees. GraPhlAn focuses on concise, integrative, informative, and publication-ready representations of phylogenetically- and taxonomically-driven investigation. Phylogenetic inference, Phylogenetic tree visualisation, Phylogenetic tree editing, Taxonomic classification Metagenomics, Phylogenetics, Phylogenomics, Cladistics To update https://github.com/biobakery/graphlan Metagenomics, Graphics, Phylogenetics graphlan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/humann2/ graphlan 1.1.3 (2/2) (2/2) (2/2) True True -gtdbtk gtdbtk_classify_wf GTDB-Tk is a software tool kit for assigning objective taxonomic classifications to bacterial and archaeal genomesbased on the Genome Database Taxonomy GTDB. It is designed to work with recent advances that allow hundreds orthousands of metagenome-assembled genomes (MAGs) to be obtained directly from environmental samples. It can alsobe applied to isolate and single-cell genomes. GTDB-Tk GTDB-Tk a toolkit to classify genomes with the Genome Taxonomy Database.GTDB-Tk: a toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes.GTDB-Tk is a software toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes based on the Genome Database Taxonomy GTDB. It is designed to work with recent advances that allow hundreds or thousands of metagenome-assembled genomes (MAGs) to be obtained directly from environmental samples. It can also be applied to isolate and single-cell genomes. The GTDB-Tk is open source and released under the GNU General Public License (Version 3). Genome alignment, Taxonomic classification, Sequence assembly, Query and retrieval Metagenomics, Taxonomy, Phylogenetics, Database management, Proteins Up-to-date https://github.com/Ecogenomics/GTDBTk Metagenomics gtdbtk iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gtdbtk 2.3.2 gtdbtk 2.3.2 (0/1) (1/1) (0/1) True True -gubbins 3340.0 145.0 gubbins Gubbins - bacterial recombination detection gubbins Gubbins Gubbins is a tool for rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences. Genotyping, Phylogenetic inference, Ancestral reconstruction Phylogeny, Genotype and phenotype, Whole genome sequencing To update Sequence Analysis gubbins iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gubbins 3.2.1 gubbins 3.3.3 (1/1) (1/1) (1/1) True True -gwastools gwastools_manhattan_plot gwastools GWASTools Classes for storing very large GWAS data sets and annotation, and functions for GWAS data cleaning and analysis. Deposition, Analysis, Annotation GWAS study To update https://bioconductor.org/packages/release/bioc/html/GWASTools.html Visualization, Variant Analysis iuc 0.1.0 bioconductor-gwastools 1.48.0 (0/1) (0/1) (0/1) True False -hamronization hamronize_summarize, hamronize_tool Convert AMR gene detection tool output to hAMRonization specification format. hamronization hAMRonization Parse multiple Antimicrobial Resistance Analysis Reports into a common data structure Data handling, Antimicrobial resistance prediction, Parsing Public health and epidemiology, Microbiology, Bioinformatics To update https://github.com/pha4ge/hAMRonization Sequence Analysis hamronization iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hamronization 1.0.3 hamronization 1.1.4 (0/2) (0/2) (2/2) True True -hansel bio_hansel Heidelberg and Enteritidis SNP Elucidation Biohansel BioHansel BioHansel is a tool for performing high-resolution genotyping of bacterial isolates by identifying phylogenetically informative single nucleotide polymorphisms (SNPs), also known as canonical SNPs, in whole genome sequencing (WGS) data. The application uses a fast k-mer matching algorithm to map pathogen WGS data to canonical SNPs contained in hierarchically structured schemas and assigns genotypes based on the detected SNP profile. Genotyping, SNP detection, Genome assembly Whole genome sequencing, DNA polymorphism, Genotype and phenotype, Infectious disease, Agricultural science Up-to-date https://github.com/phac-nml/bio_hansel Sequence Analysis bio_hansel iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hansel 2.6.1 bio_hansel 2.6.1 (1/1) (0/1) (1/1) True True -hapcut2 hapcut2 Robust and accurate haplotype assembly for diverse sequencing technologies hapcut2 HapCUT2 "HapCUT2 is a maximum-likelihood-based tool for assembling haplotypes from DNA sequence reads, designed to ""just work"" with excellent speed and accuracy across a range of long- and short-read sequencing technologies.The output is in Haplotype block format described here: https://github.com/vibansal/HapCUT2/blob/master/outputformat.md" Haplotype mapping, Variant classification Up-to-date https://github.com/vibansal/HapCUT2 Assembly hapcut2 galaxy-australia https://github.com/galaxyproject/tools-iuc 1.3.3 hapcut2 1.3.3 (0/1) (1/1) (0/1) True False -hapog 295.0 36.0 hapog Hapo-G - Haplotype-Aware Polishing of Genomes hapog Hapo-G Hapo-G is a tool that aims to improve the quality of genome assemblies by polishing the consensus with accurate reads. It capable of incorporating phasing information from high-quality reads (short or long-reads) to polish genome assemblies and in particular assemblies of diploid and heterozygous genomes. Genome assembly, Optimisation and refinement Sequence assembly, Genomics Up-to-date https://github.com/institut-de-genomique/HAPO-G Assembly hapog iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hapog 1.3.7 hapog 1.3.7 (0/1) (0/1) (1/1) True False -heatmap2 ggplot2_heatmap2 heatmap.2 function from the R gplots package To update https://github.com/cran/gplots Visualization ggplot2_heatmap2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/heatmap2 3.1.3.1 r-gplots 2.17.0 (1/1) (1/1) (1/1) True False -heinz 1186.0 242.0 heinz_bum, heinz, heinz_scoring, heinz_visualization An algorithm for identification of the optimal scoring subnetwork. bionet BioNet This package provides functions for the integrated analysis of protein-protein interaction networks and the detection of functional modules. Different datasets can be integrated into the network by assigning p-values of statistical tests to the nodes of the network. By fitting a beta-uniform mixture model and calculating scores from these p-values, overall scores of network regions can be calculated and an integer linear programming algorithm identifies the maximum scoring subnetwork. Protein interaction analysis Molecular interactions, pathways and networks, Protein interactions To update https://github.com/ls-cwi/heinz Transcriptomics, Visualization, Statistics heinz iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/heinz 1.0 bioconductor-bionet 1.62.0 (4/4) (4/4) (4/4) True False -hicexplorer hicexplorer_chicaggregatestatistic, hicexplorer_chicdifferentialtest, hicexplorer_chicexportdata, hicexplorer_chicplotviewpoint, hicexplorer_chicqualitycontrol, hicexplorer_chicsignificantinteractions, hicexplorer_chicviewpoint, hicexplorer_chicviewpointbackgroundmodel, hicexplorer_hicadjustmatrix, hicexplorer_hicaggregatecontacts, hicexplorer_hicaverageregions, hicexplorer_hicbuildmatrix, hicexplorer_hiccomparematrices, hicexplorer_hiccompartmentspolarization, hicexplorer_hicconvertformat, hicexplorer_hiccorrectmatrix, hicexplorer_hiccorrelate, hicexplorer_hicdetectloops, hicexplorer_hicdifferentialtad, hicexplorer_hicfindrestrictionsites, hicexplorer_hicfindtads, hicexplorer_hichyperoptDetectLoops, hicexplorer_hicinfo, hicexplorer_hicinterintratad, hicexplorer_hicmergedomains, hicexplorer_hicmergeloops, hicexplorer_hicmergematrixbins, hicexplorer_hicnormalize, hicexplorer_hicpca, hicexplorer_hicplotaverageregions, hicexplorer_hicplotdistvscounts, hicexplorer_hicplotmatrix, hicexplorer_hicplotsvl, hicexplorer_hicplotviewpoint, hicexplorer_hicquickqc, hicexplorer_hicsummatrices, hicexplorer_hictadclassifier, hicexplorer_hictraintadclassifier, hicexplorer_hictransform, hicexplorer_hicvalidatelocations HiCExplorer: Set of programs to process, analyze and visualize Hi-C data. To update https://github.com/deeptools/HiCExplorer Sequence Analysis, Visualization hicexplorer bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/hicexplorer 3.7.2 hicexplorer 3.7.3 (0/40) (5/40) (40/40) True False -hicstuff hicstuff_pipeline To update https://github.com/koszullab/hicstuff Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hicstuff 3.1.5 hicstuff 3.2.2 (0/1) (0/1) (0/1) True False -hifiasm_meta 137.0 12.0 hifiasm_meta A hifiasm fork for metagenome assembly using Hifi reads. hifiasm-meta Hifiasm-meta Hifiasm_meta - de novo metagenome assembler, based on hifiasm, a haplotype-resolved de novo assembler for PacBio Hifi reads. Sequence assembly Sequence assembly, Metagenomics To update https://github.com/xfengnefx/hifiasm-meta Metagenomics hifiasm_meta galaxy-australia https://github.com/galaxyproject/tools-iuc/tree/master/tools/hifiasm_meta 0.3.1 hifiasm_meta hamtv0.3.1 (0/1) (1/1) (1/1) True True -hisat2 299104.0 4183.0 hisat2 HISAT2 is a fast and sensitive spliced alignment program. hisat2 HISAT2 Alignment program for mapping next-generation sequencing reads (both DNA and RNA) to a population of human genomes (as well as to a single reference genome). Sequence alignment RNA-seq Up-to-date http://ccb.jhu.edu/software/hisat2/ Assembly hisat2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hisat2 2.2.1 hisat2 2.2.1 (1/1) (1/1) (1/1) True False -hmmer3 21049.0 111.0 hmmer_alimask, hmmer_hmmalign, hmmer_hmmbuild, hmmer_hmmconvert, hmmer_hmmemit, hmmer_hmmfetch, hmmer_hmmscan, hmmer_hmmsearch, hmmer_jackhmmer, hmmer_nhmmer, hmmer_nhmmscan, hmmer_phmmer HMMER is used for searching sequence databases for homologs of proteinsequences, and for making protein sequence alignments. It implementsmethods using probabilistic models called profile hidden Markov models(profile HMMs). hmmer3 HMMER3 This tool is used for searching sequence databases for homologs of protein sequences, and for making protein sequence alignments. It implements methods using probabilistic models called profile hidden Markov models. The new HMMER3 project, HMMER is now as fast as BLAST for protein search. Formatting, Multiple sequence alignment, Sequence profile generation, Format validation, Conversion, Sequence generation, Data retrieval, Statistical calculation, Database search, Formatting, Database search, Database search, Probabilistic sequence generation, Statistical calculation, Statistical calculation, Sequence database search, Formatting, Sequence database search, Database search, Sequence database search Sequence analysis, Sequence sites, features and motifs, Gene and protein families Up-to-date http://hmmer.org/ Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 3.4 hmmer 3.4 (0/12) (12/12) (12/12) True True -homer homer_annotatePeaks, homer_findMotifs, homer_findMotifsGenome, homer_gtf_to_annotations, homer_scanMotifGenomeWide HOMER (Hypergeometric Optimization of Motif EnRichment) is a suite of tools for Motif Discovery and next-gen sequencing analysis. homer homer HOMER contains a novel motif discovery algorithm that was designed for regulatory element analysis in genomics applications (DNA only, no protein). It is a differential motif discovery algorithm, which means that it takes two sets of sequences and tries to identify the regulatory elements that are specifically enriched in on set relative to the other. It uses ZOOPS scoring (zero or one occurrence per sequence) coupled with the hypergeometric enrichment calculations (or binomial) to determine motif enrichment. HOMER also tries its best to account for sequenced bias in the dataset. It was designed with ChIP-Seq and promoter analysis in mind, but can be applied to pretty much any nucleic acids motif finding problem. Sequence motif discovery Up-to-date http://homer.ucsd.edu/homer/index.html Sequence Analysis data_manager_homer_preparse iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/homer 4.11 homer 4.11 (0/5) (0/5) (5/5) True False -htseq_count 154533.0 1419.0 htseq_count Count aligned reads (SAM/BAM) that overlap genomic features (GFF) htseq HTSeq Python framework to process and analyse high-throughput sequencing (HTS) data Nucleic acid sequence analysis Sequence analysis Up-to-date https://readthedocs.org/projects/htseq/ Genomic Interval Operations, SAM, Sequence Analysis, RNA htseq_count lparsons https://github.com/galaxyproject/tools-iuc/tree/master/tools/htseq_count 2.0.5 htseq 2.0.5 (1/1) (1/1) (1/1) True False -humann 5856.0 247.0 humann, humann_associate, humann_barplot, humann_join_tables, humann_reduce_table, humann_regroup_table, humann_rename_table, humann_renorm_table, humann_rna_dna_norm, humann_split_stratified_table, humann_split_table, humann_strain_profiler, humann_unpack_pathways HUMAnN for functionally profiling metagenomes and metatranscriptomes at species-level resolution humann humann HUMAnN is a pipeline for efficiently and accurately profiling the presence/absence and abundance of microbial pathways in a community from metagenomic or metatranscriptomic sequencing data (typically millions of short DNA/RNA reads). This process, referred to as functional profiling, aims to describe the metabolic potential of a microbial community and its members. More generally, functional profiling answers the question “What are the microbes in my community-of-interest doing (or are capable of doing)?” Species frequency estimation, Taxonomic classification, Phylogenetic analysis Metagenomics, Phylogenomics Up-to-date http://huttenhower.sph.harvard.edu/humann Metagenomics humann iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/humann 3.8 humann 3.8 (6/13) (12/13) (13/13) True True -hybpiper hybpiper Analyse targeted sequence capture data HybPiper HybPiper Paralogs and off-target sequences improve phylogenetic resolution in a densely-sampled study of the breadfruit genus (Artocarpus, Moraceae).Recovering genes from targeted sequence capture data.Current version: 1.3.1 (August 2018).-- Read our article in Applications in Plant Sciences (Open Access).HybPiper was designed for targeted sequence capture, in which DNA sequencing libraries are enriched for gene regions of interest, especially for phylogenetics. HybPiper is a suite of Python scripts that wrap and connect bioinformatics tools in order to extract target sequences from high-throughput DNA sequencing reads. Sequence trimming, Sequence assembly, Read mapping Phylogenetics, Plant biology, Gene transcripts, Sequence assembly, Phylogenomics Up-to-date https://github.com/mossmatters/HybPiper Sequence Analysis, Phylogenetics hybpiper iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hybpiper 2.1.6 hybpiper 2.1.6 (0/1) (1/1) (0/1) True False -hyphy hyphy_absrel, hyphy_annotate, hyphy_bgm, hyphy_busted, hyphy_cfel, hyphy_conv, hyphy_fade, hyphy_fel, hyphy_fubar, hyphy_gard, hyphy_meme, hyphy_prime, hyphy_relax, hyphy_slac, hyphy_sm19, hyphy_strike_ambigs, hyphy_summary Hypothesis Testing using Phylogenies HyPhy HyPhy Software package for the analysis of genetic sequences using techniques in phylogenetics, molecular evolution, and machine learning. Statistical calculation Phylogeny, Small molecules, Molecular interactions, pathways and networks To update http://www.hyphy.org Phylogenetics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ 2.5.47 hyphy 2.5.59 (17/17) (2/17) (17/17) True True -hypo 354.0 39.0 hypo Super Fast & Accurate Polisher for Long Read Genome Assemblies HyPo HyPo HyPo, a Hybrid Polisher, utilizes short as well as long reads within a single run to polish a long reads assembly of small and large genomes. Optimisation and refinement, Genome assembly Sequence assembly, Genomics Up-to-date https://github.com/kensung-lab/hypo Assembly hypo iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hypo 1.0.3 hypo 1.0.3 (0/1) (0/1) (1/1) True True -icescreen icescreen ICEscreen identifies Integrative Conjugative Elements (ICEs) and Integrative Mobilizable Elements (IMEs) in Bacillota genomes. icescreen ICEscreen A tool to detect Firmicute ICEs and IMEs, isolated or enclosed in composite structures. Database search, Protein feature detection Mobile genetic elements, Sequence sites, features and motifs, Genomics, Molecular interactions, pathways and networks, Structural variation To update https://icescreen.migale.inrae.fr/ Genome annotation icescreen iuc https://forgemia.inra.fr/ices_imes_analysis/icescreen 1.3.1 icescreen 1.3.2 (0/1) (0/1) (0/1) True True -idba_ud 721.0 43.0 idba_hybrid, idba_tran, idba_ud Wrappers for the idba assembler variants. idba IDBA A short read assembler based on iterative De Bruijn graph. It is developed under 64-bit Linux, but should be suitable for all unix-like system. Sequence assembly Sequence assembly To update https://i.cs.hku.hk/~alse/hkubrg/projects/index.html Assembly idba iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/idba_ud idba 1.1.3 (3/3) (0/3) (3/3) True True -idr 2873.0 30.0 idr Galaxy wrappers for the IDR package from Nathan Boleu To update https://github.com/nboley/idr Sequence Analysis idr iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/idr/ 2.0.3 idr 2.0.4.2 (1/1) (0/1) (1/1) True False -iedb_api 1506.0 12.0 iedb_api Get epitope binding predictions from IEDB-API To update http://tools.immuneepitope.org/main/tools-api/ Data Source, Sequence Analysis iedb_api iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/iedb_api 2.15.2 python (0/1) (0/1) (1/1) True False -instrain instrain_compare, instrain_profile InStrain is a tool for analysis of co-occurring genome populations from metagenomes instrain InStrain InStrain is a tool for analysis of co-occurring genome populations from metagenomes that allows highly accurate genome comparisons, analysis of coverage, microdiversity, and linkage, and sensitive SNP detection with gene localization and synonymous non-synonymous identification SNP detection, Genome comparison Mapping, Metagenomics To update https://instrain.readthedocs.io/en/latest/# Metagenomics instrain iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/instrain 1.5.3 instrain 1.8.0 (0/2) (0/2) (2/2) True True -integron_finder 52965.0 58.0 integron_finder """IntegronFinder identify integrons with high accuracy and sensitivity.It searches for attC sites using covariance models, for integron-integrases using HMM profiles, and for other features (promoters, attI site) using pattern matching""" integron_finder Integron Finder A tool to detect Integron in DNA sequences. Nucleic acid feature detection, Sequence motif recognition, Protein feature detection, Genome annotation Functional genomics, Mobile genetic elements, Molecular biology, Sequence analysis Up-to-date https://github.com/gem-pasteur/Integron_Finder Sequence Analysis integronfinder iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/integron_finder 2.0.3 integron_finder 2.0.3 (0/1) (1/1) (1/1) True False -interproscan 5294.0 554.0 interproscan Interproscan queries the interpro database and provides annotations. interproscan_ebi InterProScan (EBI) Scan sequences against the InterPro protein signature databases. Sequence motif recognition, Protein feature detection Gene and protein families, Sequence analysis To update http://www.ebi.ac.uk/Tools/pfa/iprscan5/ Sequence Analysis interproscan bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/interproscan 5.59-91.0 interproscan 5.59_91.0 (1/1) (1/1) (1/1) True True -iqtree 21598.0 681.0 iqtree Efficient phylogenomic software by maximum likelihood To update http://www.iqtree.org/ Phylogenetics iqtree iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/iqtree/ 2.1.2 iqtree 2.2.6 (1/1) (1/1) (1/1) True True -isescan 57581.0 50.0 isescan """ISEScan is a pipeline to identify IS (Insertion Sequence) elements in genome and metagenomebased on profile hidden Markov models constructed from manually curated IS elements.""" ISEScan ISEScan Automated identification of insertion sequence elements in prokaryotic genomes. Structural variation detection Genomics, DNA structural variation, Sequence analysis, Genetic variation To update https://github.com/xiezhq/ISEScan Sequence Analysis ISEScan iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/isescan 1.7.2.3 isescan 1.7.2.1 (0/1) (1/1) (1/1) True False -isoformswitchanalyzer 822.0 29.0 isoformswitchanalyzer Statistical identification of isoform switching from RNA-seq derived quantification of novel and/or annotated full-length isoforms. IsoformSwitchAnalyzeR IsoformSwitchAnalyzeR Enables identification of isoform switches with predicted functional consequences from RNA-seq data. Consequences can be chosen from a long list but includes protein domains gain/loss changes in NMD sensitivity etc. It directly supports import of data from Cufflinks/Cuffdiff, Kallisto, Salmon and RSEM but other transcript qunatification tools are easy to import as well. Sequence comparison, Sequence analysis Computational biology, Gene transcripts To update https://bioconductor.org/packages/devel/bioc/html/IsoformSwitchAnalyzeR.html Transcriptomics, RNA, Statistics isoformswitchanalyzer iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/isoformswitchanalyzer 1.20.0 bioconductor-isoformswitchanalyzer 2.2.0 (1/1) (1/1) (1/1) True False -ivar ivar_consensus, ivar_filtervariants, ivar_removereads, ivar_trim, ivar_variants iVar is a computational package that contains functions broadly useful for viral amplicon-based sequencing Up-to-date https://github.com/andersen-lab/ivar Sequence Analysis ivar iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ivar/ 1.4.2 ivar 1.4.2 (5/5) (5/5) (5/5) True True -jbrowse 18229.0 2346.0 jbrowse_to_standalone, jbrowse JBrowse Genome Browser integrated as a Galaxy Tool jbrowse JBrowse Slick, speedy genome browser with a responsive and dynamic AJAX interface for visualization of genome data. Being developed by the GMOD project as a successor to GBrowse. Genome visualisation Genomics Up-to-date https://jbrowse.org Sequence Analysis jbrowse iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/jbrowse 1.16.11 jbrowse 1.16.11 (2/2) (2/2) (2/2) True True -jcvi_gff_stats 2469.0 255.0 jcvi_gff_stats Compute statistics from a genome annotation in GFF3 format (using JCVI Python utilities) To update https://github.com/tanghaibao/jcvi Sequence Analysis jcvi_gff_stats iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/jcvi_gff_stats 0.8.4 jcvi 1.3.9 (1/1) (1/1) (1/1) True False -jellyfish 1138.0 91.0 jellyfish Jellyfish is a tool for fast, memory-efficient counting of k-mers in DNA Jellyfish Jellyfish A command-line algorithm for counting k-mers in DNA sequence. k-mer counting Sequence analysis, Genomics To update https://github.com/gmarcais/Jellyfish Assembly jellyfish iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/jellyfish kmer-jellyfish 2.3.1 (0/1) (1/1) (1/1) True True -kc-align kc-align Kc-Align custom tool kc-align kc-align A fast and accurate tool for performing codon-aware multiple sequence alignments Multiple sequence alignment Mapping Up-to-date https://github.com/davebx/kc-align Sequence Analysis kc_align iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/kc-align 1.0.2 kcalign 1.0.2 (1/1) (0/1) (1/1) True True -khmer khmer_abundance_distribution_single, khmer_abundance_distribution, khmer_count_median, khmer_partition, khmer_extract_partitions, khmer_filter_abundance, khmer_filter_below_abundance_cutoff, khmer_normalize_by_median In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more khmer khmer khmer is a set of command-line tools for working with DNA shotgun sequencing data from genomes, transcriptomes, metagenomes, and single cells. khmer can make de novo assemblies faster, and sometimes better. khmer can also identify (and fix) problems with shotgun data. Standardisation and normalisation, De-novo assembly Sequence assembly Up-to-date https://khmer.readthedocs.org/ Assembly, Next Gen Mappers khmer iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/khmer 3.0.0a3 khmer 3.0.0a3 (8/8) (8/8) (8/8) True True -kleborate 319.0 38.0 kleborate Screen genome assemblies of Klebsiella pneumoniae and the Klebsiella pneumoniae species complex (KpSC) kleborate Kleborate Genomic surveillance framework and global population structure for Klebsiella pneumoniae.Kleborate is a tool to screen genome assemblies of Klebsiella pneumoniae and the Klebsiella pneumoniae species complex (KpSC) for:.A manuscript describing the Kleborate software in full is currently in preparation. In the meantime, if you use Kleborate, please cite the preprint: Lam, MMC. et al. Genomic surveillance framework and global population structure for Klebsiella pneumoniae. bioRxiv (2020). Multilocus sequence typing, Genome assembly, Virulence prediction Public health and epidemiology, Metagenomics, Population genomics, Sequence assembly, Whole genome sequencing Up-to-date https://github.com/katholt/Kleborate/wiki Metagenomics kleborate iuc https://github.com/katholt/Kleborate 2.3.2 kleborate 2.3.2 (0/1) (0/1) (1/1) True True -kofamscan 594.0 33.0 kofamscan Gene function annotation tool based on KEGG Orthology and hidden Markov model Up-to-date https://github.com/takaram/kofam_scan Sequence Analysis kofamscan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/kofamscan 1.3.0 kofamscan 1.3.0 (0/1) (0/1) (1/1) True True -kraken_biom 1444.0 182.0 kraken_biom Create BIOM-format tables (http://biom-format.org) from Kraken output (http://ccb.jhu.edu/software/kraken/) Up-to-date https://github.com/smdabdoub/kraken-biom Metagenomics kraken_biom iuc https://github.com/smdabdoub/kraken-biom 1.2.0 kraken-biom 1.2.0 (0/1) (1/1) (1/1) True True -kraken_taxonomy_report 2527.0 354.0 kraken_taxonomy_report Kraken taxonomy report To update https://github.com/blankenberg/Kraken-Taxonomy-Report Metagenomics kraken_taxonomy_report iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/kraken_taxonomy_report 0.0.3 biopython 1.70 (1/1) (1/1) (1/1) True True -krakentools krakentools_alpha_diversity, krakentools_beta_diversity, krakentools_combine_kreports, krakentools_extract_kraken_reads, krakentools_kreport2krona, krakentools_kreport2mpa KrakenTools is a suite of scripts to be used alongside the Kraken krakentools KrakenTools KrakenTools provides individual scripts to analyze Kraken/Kraken2/Bracken/KrakenUniq output files Visualisation, Aggregation Taxonomy, Metagenomics Up-to-date https://github.com/jenniferlu717/KrakenTools Metagenomics krakentools iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/krakentools 1.2 krakentools 1.2 (1/6) (6/6) (6/6) True True -krocus krocus Predict MLST directly from uncorrected long reads To update https://github.com/quadram-institute-bioscience/krocus Sequence Analysis krocus iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/krocus 1.0.1 krocus 1.0.3 (0/1) (0/1) (0/1) True True -last 227.0 41.0 last_al, last_db, last_split, last_train, last_maf_convert LAST finds similar regions between sequences. last LAST Short read alignment program incorporating quality scores Sequence alignment Genomics, Comparative genomics To update http://last.cbrc.jp/ Sequence Analysis last iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/last 1205 last 1542 (0/5) (0/5) (5/5) True False -legsta 55.0 7.0 legsta Performs in silico Legionella pneumophila sequence based typing. Up-to-date https://github.com/tseemann/legsta Sequence Analysis legsta iuc https://github.com/tseemann/legsta 0.5.1 legsta 0.5.1 (0/1) (0/1) (1/1) True True -length_and_gc_content 4090.0 322.0 length_and_gc_content Gets gene length and gc content from a fasta and a GTF file To update https://github.com/galaxyproject/tools-iuc/tree/master/tools/length_and_gc_content Fasta Manipulation, Statistics, RNA, Micro-array Analysis length_and_gc_content iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/length_and_gc_content 0.1.2 r-optparse 1.3.2 (1/1) (1/1) (1/1) True False -limma_voom 20344.0 1012.0 limma_voom Perform RNA-Seq differential expression analysis using limma voom pipeline limma limma Data analysis, linear models and differential expression for microarray data. RNA-Seq analysis Molecular biology, Genetics Up-to-date http://bioconductor.org/packages/release/bioc/html/limma.html Transcriptomics, RNA, Statistics limma_voom iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/limma_voom 3.58.1 bioconductor-limma 3.58.1 (1/1) (1/1) (1/1) True False -lineagespot 37.0 2.0 lineagespot Identification of SARS-CoV-2 related metagenomic mutations based on a single (or a list of) variant(s) file(s) lineagespot lineagespot Lineagespot is a framework written in R, and aims to identify and assign different SARS-CoV-2 lineages based on a single variant file (i.e., variant calling format). Variant calling Metagenomics, Gene transcripts, Evolutionary biology, Sequencing, Genetic variation To update https://www.bioconductor.org/packages/release/bioc/html/lineagespot.html Metagenomics, Sequence Analysis lineagespot iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/lineagespot 1.6.0 r-base (0/1) (0/1) (1/1) True True -links 405.0 77.0 links Scaffold genome assemblies with long reads. links LINKS LINKS (Long Interval Nucleotide K-mer Scaffolder) is a genomics application for scaffolding genome assemblies with long reads, such as those produced by Oxford Nanopore Technologies Ltd. It can be used to scaffold high-quality draft genome assemblies with any long sequences (eg. ONT reads, PacBio reads, other draft genomes, etc). It is also used to scaffold contig pairs linked by ARCS/ARKS. Scaffolding, Genome assembly, Read mapping, Read pre-processing, Sequence trimming Sequence assembly, Mapping, Sequencing Up-to-date https://github.com/bcgsc/LINKS Assembly links iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/links 2.0.1 links 2.0.1 (0/1) (1/1) (1/1) True False -lorikeet lorikeet_spoligotype Tools for M. tuberculosis DNA fingerprinting (spoligotyping) Up-to-date https://github.com/AbeelLab/lorikeet Sequence Analysis lorikeet_spoligotype iuc https://github.com/AbeelLab/lorikeet 20 lorikeet 20 (0/1) (0/1) (1/1) True True -m6anet 3.0 m6anet m6anet to detect m6A RNA modifications from nanopore data m6Anet m6Anet Detection of m6A from direct RNA sequencing using a Multiple Instance Learning framework. Quantification, Imputation, Gene expression profiling RNA-Seq, Transcriptomics, RNA, Machine learning Up-to-date https://m6anet.readthedocs.io/en/latest Sequence Analysis m6anet iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/m6anet 2.1.0 m6anet 2.1.0 (0/1) (0/1) (1/1) True True -maaslin2 188.0 29.0 maaslin2 MaAsLin2 is comprehensive R package for efficiently determining multivariable association between microbial meta'omic features and clinical metadata. Up-to-date http://huttenhower.sph.harvard.edu/maaslin Metagenomics maaslin2 iuc https://github.com/biobakery/Maaslin2 0.99.12 maaslin2 0.99.12 (0/1) (0/1) (1/1) True True -macs2 84202.0 1968.0 macs2_bdgbroadcall, macs2_bdgcmp, macs2_bdgdiff, macs2_bdgpeakcall, macs2_callpeak, macs2_filterdup, macs2_predictd, macs2_randsample, macs2_refinepeak MACS - Model-based Analysis of ChIP-Seq macs MACS Model-based Analysis of ChIP-seq data. Peak calling, Enrichment analysis, Gene regulatory network analysis ChIP-seq, Molecular interactions, pathways and networks, Transcription factors and regulatory sites Up-to-date https://github.com/taoliu/MACS Sequence Analysis, Statistics macs2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/macs2 2.2.9.1 macs2 2.2.9.1 (9/9) (9/9) (9/9) True False -maker 4950.0 419.0 maker, maker_map_ids MAKER is a portable and easily configurable genome annotation pipeline.Its purpose is to allow smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. maker MAKER Portable and easily configurable genome annotation pipeline. It’s purpose is to allow smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. Genome annotation Genomics, DNA, Sequence analysis To update http://www.yandell-lab.org/software/maker.html Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/maker 2.31.11 maker 3.01.03 (2/2) (2/2) (2/2) True True -mapseq 167.0 2.0 mapseq fast and accurate sequence read classification tool designed to assign taxonomy and OTU classifications to ribosomal RNA sequences. To update https://github.com/jfmrod/MAPseq Metagenomics mapseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mapseq 2.1.1 perl (0/1) (0/1) (1/1) True True -mash 1739.0 12.0 mash_screen, mash_sketch Fast genome and metagenome distance estimation using MinHash mash Mash Fast genome and metagenome distance estimation using MinHash. Sequence distance matrix generation Genomics, Metagenomics, Statistics and probability, Sequence analysis, DNA mutation Up-to-date https://github.com/marbl/Mash Metagenomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mash 2.3 mash 2.3 (2/2) (2/2) (2/2) True True -mashmap mashmap Fast local alignment boundaries Up-to-date https://github.com/galaxyproject/tools-iuc/tree/master/tools/mashmap Sequence Analysis mashmap iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mashmap 3.1.3 mashmap 3.1.3 (0/1) (0/1) (1/1) False -masigpro 576.0 13.0 masigpro Identify significantly differential expression profiles in time-course microarray experiments masigpro maSigPro Regression based approach to find genes for which there are significant gene expression profile differences between experimental groups in time course microarray and RNA-Seq experiments. Regression analysis Gene expression, Molecular genetics, Microarray experiment, RNA-Seq To update https://www.bioconductor.org/packages/release/bioc/html/maSigPro.html Transcriptomics, RNA, Statistics masigpro iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/masigpro 1.49.3 coreutils 8.25 (1/1) (0/1) (1/1) True False -maxbin2 2059.0 118.0 maxbin2 clusters metagenomic contigs into bins maxbin MaxBin Software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm. Sequence assembly Metagenomics, Sequence assembly, Microbiology To update https://downloads.jbei.org/data/microbial_communities/MaxBin/MaxBin.html Metagenomics maxbin2 mbernt https://github.com/galaxyproject/tools-iuc/tree/master/tools/maxbin2/ maxbin2 2.2.7 (1/1) (1/1) (1/1) True True -mcl 29.0 10.0 mcl The Markov Cluster Algorithm, a cluster algorithm for graphs mcl MCL MCL is a clustering algorithm widely used in bioinformatics and gaining traction in other fields. Clustering, Network analysis, Gene regulatory network analysis Molecular interactions, pathways and networks Up-to-date https://micans.org/mcl/man/mcl.html Sequence Analysis mcl iuc https://github.com/galaxyproject/tools-iuc/tree/master/mcl 22.282 mcl 22.282 (0/1) (0/1) (1/1) True True -medaka medaka_consensus, medaka_consensus_pipeline, medaka_snp, medaka_variant Sequence correction provided by ONT Research medaka Medaka medaka is a tool to create consensus sequences and variant calls from nanopore sequencing data. This task is performed using neural networks applied a pileup of individual sequencing reads against a draft assembly. Base-calling, Variant calling, Sequence assembly Sequence assembly, Machine learning To update https://github.com/nanoporetech/medaka Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/medaka 1.7.2 medaka 1.11.3 (3/4) (3/4) (3/4) True True -megahit 9530.0 548.0 megahit An ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph. megahit MEGAHIT Single node assembler for large and complex metagenomics NGS reads, such as soil. It makes use of succinct de Bruijn graph to achieve low memory usage, whereas its goal is not to make memory usage as low as possible. Genome assembly Metagenomics, Sequencing, Ecology, Sequence assembly Up-to-date https://github.com/voutcn/megahit Sequence Analysis, Assembly, Metagenomics megahit iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/megahit 1.2.9 megahit 1.2.9 (1/1) (1/1) (1/1) True True -megahit_contig2fastg 475.0 54.0 megahit_contig2fastg A subprogram within the Megahit toolkit for converting contigs to assembly graphs (fastg) megahit MEGAHIT Single node assembler for large and complex metagenomics NGS reads, such as soil. It makes use of succinct de Bruijn graph to achieve low memory usage, whereas its goal is not to make memory usage as low as possible. Genome assembly Metagenomics, Sequencing, Ecology, Sequence assembly To update https://github.com/voutcn/megahit/blob/master/tools/toolkit.cpp Sequence Analysis, Assembly, Metagenomics megahit_contig2fastg iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/megahit_contig2fastg 1.1.3 megahit 1.2.9 (1/1) (0/1) (1/1) True True -megan megan_blast2lca, megan_blast2rma, megan_daa2info, megan_daa2rma, megan_daa_meganizer, megan_read_extractor, megan_sam2rma MEGAN Community Edition - Interactive exploration and analysis of large-scale microbiome sequencing data. MEGAN is a tool for studying the taxonomic content of a set of DNA reads, typically collected in a metagenomics project.In a preprocessing step, a sequence alignment of all reads against a suitable database of reference DNA or proteinsequences must be performed to produce an input file for the program. MEGAN is suitable for DNA reads (metagenomedata), RNA reads (metatranscriptome data), peptide sequences (metaproteomics data) and, using a suitable synonymsfile that maps SILVA ids to taxon ids, for 16S rRNA data (amplicon sequencing). megan MEGAN Metagenome Analysis Software - MEGAN (MEtaGenome ANalyzer) is a new computer program that allows laptop analysis of large metagenomic datasets. In a preprocessing step, the set of DNA reads (or contigs) is compared against databases of known sequences using BLAST or another comparison tool. MEGAN can then be used to compute and interactively explore the taxonomical content of the dataset, employing the NCBI taxonomy to summarize and order the results. Sequence analysis, Taxonomic classification Sequence analysis To update https://github.com/husonlab/megan-ce Sequence Analysis megan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/megan 6.21.7 megan 6.25.9 (0/7) (0/7) (7/7) True True -meningotype meningotype Assign sequence type to N. meningitidis genome assemblies Up-to-date https://github.com/MDU-PHL/meningotype Sequence Analysis meningotype iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/meningotype 0.8.5 meningotype 0.8.5 (0/1) (0/1) (0/1) True True -merqury 2483.0 244.0 merqury, merquryplot Merqury is a tool for evaluating genomes assemblies based of k-mer operations. merqury Merqury Reference-free quality, completeness, and phasing assessment for genome assemblies.Evaluate genome assemblies with k-mers and more.Often, genome assembly projects have illumina whole genome sequencing reads available for the assembled individual.Merqury provides a set of tools for this purpose. Genome assembly, k-mer counting, Scaffolding, Phasing, De-novo assembly Sequence assembly, Whole genome sequencing, Plant biology Up-to-date https://github.com/marbl/merqury Assembly merqury iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/merqury 1.3 merqury 1.3 (2/2) (2/2) (2/2) True True -meryl 6785.0 350.0 meryl Meryl a k-mer counter. meryl Meryl Meryl is a tool for counting and working with sets of k-mers that was originally developed for use in the Celera Assembler and has since been migrated and maintained as part of Canu. k-mer counting Whole genome sequencing, Genomics, Sequence analysis, Sequencing Up-to-date https://github.com/marbl/meryl Assembly meryl iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/meryl 1.3 merqury 1.3 (1/1) (1/1) (1/1) True True -metabat2 4072.0 154.0 metabat2_jgi_summarize_bam_contig_depths, metabat2 MetaBAT2 (Metagenome Binning based on Abundance and Tetranucleotide frequency) is an automated metagenome binningsoftware that integrates empirical probabilistic distances of genome abundance and tetranucleotide frequency. MetaBAT_2 MetaBAT 2 "an adaptive binning algorithm for robust and efficient genome reconstruction from metagenome assemblies | MetaBAT2 clusters metagenomic contigs into different ""bins"", each of which should correspond to a putative genome | MetaBAT2 uses nucleotide composition information and source strain abundance (measured by depth-of-coverage by aligning the reads to the contigs) to perform binning" Read binning, Sequence assembly, Genome annotation Metagenomics, Sequence assembly, Metagenomic sequencing Up-to-date https://bitbucket.org/berkeleylab/metabat/src/master/ Metagenomics metabat2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/metabat2/ 2.15 metabat2 2.15 (2/2) (1/2) (2/2) True True -metaeuk metaeuk_easy_predict MetaEuk is a modular toolkit designed for large-scale gene discovery andannotation in eukaryotic metagenomic contigs. Metaeuk combines the fast andsensitive homology search capabilities of MMseqs2 with a dynamic programmingprocedure to recover optimal exons sets. It reduces redundancies in multiplediscoveries of the same gene and resolves conflicting gene predictions onthe same strand. MetaEuk MetaEuk MetaEuk - sensitive, high-throughput gene discovery and annotation for large-scale eukaryotic metagenomics Homology-based gene prediction Metagenomics, Gene and protein families To update https://github.com/soedinglab/metaeuk Sequence Analysis, Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/metaeuk 5.34c21f2 metaeuk 6.a5d39d9 (0/1) (0/1) (1/1) True True -metagenomeseq metagenomeseq_normalizaton metagenomeSeq Normalization metagenomeseq metagenomeSeq Designed to determine features (be it Operational Taxanomic Unit (OTU), species, etc.) that are differentially abundant between two or more groups of multiple samples. It is designed to address the effects of both normalization and under-sampling of microbial communities on disease association detection and the testing of feature correlations. Sequence visualisation, Statistical calculation Metagenomics, Sequencing To update Metagenomics metagenomeseq_normalization iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/metagenomeseq 1.16.0-0.0.1 bioconductor-metagenomeseq 1.43.0 (1/1) (0/1) (1/1) True True -metaphlan 10507.0 427.0 customize_metaphlan_database, extract_metaphlan_database, merge_metaphlan_tables, metaphlan MetaPhlAn for Metagenomic Phylogenetic Analysis metaphlan MetaPhlAn Computational tool for profiling the composition of microbial communities from metagenomic shotgun sequencing data. Nucleic acid sequence analysis, Phylogenetic tree analysis Metagenomics, Phylogenomics To update https://github.com/biobakery/MetaPhlAn Metagenomics metaphlan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/metaphlan/ 4.0.6 metaphlan 4.1.0 (1/4) (2/4) (4/4) True True -migmap 1226.0 7.0 migmap mapper for full-length T- and B-cell repertoire sequencing MiGMAP MiGMAP Mapper for full-length T- and B-cell repertoire sequencing. Sequence analysis, Read mapping Immunoproteins, genes and antigens, Sequence analysis Up-to-date https://github.com/mikessh/migmap RNA, Sequence Analysis migmap iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/migmap 1.0.3 migmap 1.0.3 (1/1) (0/1) (1/1) True False -minia 2206.0 109.0 minia Short-read assembler based on a de Bruijn graph minia Minia Short-read assembler based on a de Bruijn graph, capable of assembling a human genome on a desktop computer in a day. Genome assembly Sequence assembly Up-to-date https://gatb.inria.fr/software/minia/ Assembly minia iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/minia 3.2.6 minia 3.2.6 (0/1) (1/1) (1/1) True True -miniasm 11938.0 178.0 miniasm Miniasm - Ultrafast de novo assembly for long noisy reads (though having no consensus step) To update https://github.com/lh3/miniasm Assembly miniasm iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/miniasm 0.3_r179 miniasm 0.3 (1/1) (1/1) (1/1) True True -miniprot 813.0 15.0 miniprot, miniprot_index Align a protein sequence against a genome with affine gap penalty, splicing and frameshift. Up-to-date https://github.com/lh3/miniprot Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/miniprot 0.12 miniprot 0.12 (0/2) (0/2) (2/2) True True -mirnature 10.0 4.0 mirnature Computational detection of canonical microRNAs Up-to-date https://github.com/Bierinformatik/miRNAture RNA, Sequence Analysis mirnature iuc https://github.com/Bierinformatik/miRNAture 1.1 mirnature 1.1 (0/1) (0/1) (1/1) True False -mitobim 881.0 66.0 mitobim assemble mitochondrial genomes Up-to-date https://github.com/chrishah/MITObim Assembly mitobim iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mitobim 1.9.1 mitobim 1.9.1 (0/1) (1/1) (1/1) True False -mitos 32022.0 58.0 mitos, mitos2 de-novo annotation of metazoan mitochondrial genomes mitos MITOS De novo metazoan mitochondrial genome annotation. Genome annotation Zoology, Whole genome sequencing To update http://mitos.bioinf.uni-leipzig.de/ Sequence Analysis mitos iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mitos 1.1.5 mitos 2.1.7 (1/2) (1/2) (2/2) True True -mlst 9304.0 635.0 mlst, mlst_list Scan contig files against PubMLST typing schemes mlst MLST Multi Locus Sequence Typing from an assembled genome or from a set of reads. Taxonomic classification Immunoproteins, genes and antigens To update https://github.com/tseemann/mlst Sequence Analysis mlst iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mlst 2.22.0 mlst 2.23.0 (2/2) (2/2) (2/2) True True -mothur mothur_align_check, mothur_align_seqs, mothur_amova, mothur_anosim, mothur_bin_seqs, mothur_biom_info, mothur_chimera_bellerophon, mothur_chimera_ccode, mothur_chimera_check, mothur_chimera_perseus, mothur_chimera_pintail, mothur_chimera_slayer, mothur_chimera_uchime, mothur_chimera_vsearch, mothur_chop_seqs, mothur_classify_otu, mothur_classify_seqs, mothur_classify_tree, mothur_clearcut, mothur_cluster_classic, mothur_cluster_fragments, mothur_cluster_split, mothur_cluster, mothur_collect_shared, mothur_collect_single, mothur_consensus_seqs, mothur_cooccurrence, mothur_corr_axes, mothur_count_groups, mothur_count_seqs, mothur_create_database, mothur_degap_seqs, mothur_deunique_seqs, mothur_deunique_tree, mothur_dist_seqs, mothur_dist_shared, mothur_fastq_info, mothur_filter_seqs, mothur_filter_shared, mothur_get_communitytype, mothur_get_coremicrobiome, mothur_get_dists, mothur_get_group, mothur_get_groups, mothur_get_label, mothur_get_lineage, mothur_get_mimarkspackage, mothur_get_otulabels, mothur_get_otulist, mothur_get_oturep, mothur_get_otus, mothur_get_rabund, mothur_get_relabund, mothur_get_sabund, mothur_get_seqs, mothur_get_sharedseqs, mothur_heatmap_bin, mothur_heatmap_sim, mothur_homova, mothur_indicator, mothur_lefse, mothur_libshuff, mothur_list_otulabels, mothur_list_seqs, mothur_make_biom, mothur_make_contigs, mothur_make_design, mothur_make_fastq, mothur_make_group, mothur_make_lefse, mothur_make_lookup, mothur_make_shared, mothur_make_sra, mothur_mantel, mothur_merge_count, mothur_merge_files, mothur_merge_groups, mothur_merge_sfffiles, mothur_merge_taxsummary, mothur_metastats, mothur_mimarks_attributes, mothur_nmds, mothur_normalize_shared, mothur_otu_association, mothur_otu_hierarchy, mothur_pairwise_seqs, mothur_parse_list, mothur_parsimony, mothur_pca, mothur_pcoa, mothur_pcr_seqs, mothur_phylo_diversity, mothur_phylotype, mothur_pre_cluster, mothur_primer_design, mothur_rarefaction_shared, mothur_rarefaction_single, mothur_remove_dists, mothur_remove_groups, mothur_remove_lineage, mothur_remove_otulabels, mothur_remove_otus, mothur_remove_rare, mothur_remove_seqs, mothur_rename_seqs, mothur_reverse_seqs, mothur_screen_seqs, mothur_sens_spec, mothur_seq_error, mothur_sffinfo, mothur_shhh_flows, mothur_shhh_seqs, mothur_sort_seqs, mothur_split_abund, mothur_split_groups, mothur_sub_sample, mothur_summary_qual, mothur_summary_seqs, mothur_summary_shared, mothur_summary_single, mothur_summary_tax, mothur_taxonomy_to_krona, mothur_tree_shared, mothur_trim_flows, mothur_trim_seqs, mothur_unifrac_unweighted, mothur_unifrac_weighted, mothur_unique_seqs, mothur_venn Mothur wrappers mothur mothur Open-source, platform-independent, community-supported software for describing and comparing microbial communities DNA barcoding, Sequencing quality control, Sequence clustering, Taxonomic classification, Visualisation, Sequence read processing, Phylogenetic analysis Microbial ecology, Taxonomy, Sequence analysis, Phylogeny To update https://www.mothur.org Metagenomics mothur iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mothur 1.0 mothur 1.48.0 (129/129) (129/129) (129/129) True True -multigsea 53.0 2.0 multigsea GSEA-based pathway enrichment analysis for multi-omics data multiGSEA multiGSEA A GSEA-based pathway enrichment analysis for multi-omics data.multiGSEA: a GSEA-based pathway enrichment analysis for multi-omics data, BMC Bioinformatics 21, 561 (2020).Combining GSEA-based pathway enrichment with multi omics data integration. Gene-set enrichment analysis, Aggregation, Pathway analysis Metabolomics, Molecular interactions, pathways and networks, Proteomics, Transcriptomics, Small molecules Up-to-date https://bioconductor.org/packages/devel/bioc/html/multiGSEA.html Transcriptomics, Proteomics, Statistics multigsea iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/multigsea 1.12.0 bioconductor-multigsea 1.12.0 (0/1) (0/1) (1/1) True True -multiqc 162790.0 8320.0 multiqc MultiQC aggregates results from bioinformatics analyses across many samples into a single report multiqc MultiQC MultiQC aggregates results from multiple bioinformatics analyses across many samples into a single report. It searches a given directory for analysis logs and compiles a HTML report. It's a general use tool, perfect for summarising the output from numerous bioinformatics tools. Validation Sequencing, Bioinformatics To update http://multiqc.info/ Fastq Manipulation, Statistics, Visualization multiqc iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/multiqc 1.11 multiqc 1.21 (1/1) (1/1) (1/1) True True -mummer4 mummer_delta_filter, mummer_dnadiff, mummer_mummer, mummer_mummerplot, mummer_nucmer, mummer_show_coords Mummer4 Tools mumer4 MUMmer4 System for rapidly aligning large DNA sequences to one another. Multiple sequence alignment Sequence analysis, Human genetics Up-to-date https://github.com/mummer4/mummer Sequence Analysis mummer4 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mummer4 4.0.0rc1 mummer4 4.0.0rc1 (6/6) (6/6) (6/6) True False -mykrobe mykrobe_predict Antibiotic resistance predictions Mykrobe Mykrobe Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.Antibiotic resistance prediction in minutes.Table of Contents generated with DocToc.AMR prediction (Mykrobe predictor).Before attempting to install with bioconda, please ensure you have your channels set up as specified in the documentation. If you don't, you may run into issues with an older version of mykrobe being installed Antimicrobial resistance prediction, Variant calling, Genotyping, Sequence trimming Whole genome sequencing, Genotype and phenotype, Probes and primers, Genetic variation, Metagenomics To update https://github.com/Mykrobe-tools/mykrobe Sequence Analysis mykrobe iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mykrobe 0.10.0 mykrobe 0.13.0 (0/1) (0/1) (0/1) True True -naltorfs bicodon_counts_from_fasta, codon_freq_from_bicodons, find_nested_alt_orfs nAlt-ORFs: Nested Alternate Open Reading Frames (nAltORFs) Up-to-date https://github.com/BlankenbergLab/nAltORFs Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/naltorfs/ 0.1.2 naltorfs 0.1.2 (3/3) (0/3) (0/3) True False -nanocompore nanocompore_db, nanocompore_sampcomp Nanocompore compares 2 ONT nanopore direct RNA sequencing datasets from different experimental conditions expected to have a significant impact on RNA modifications. It is recommended to have at least 2 replicates per condition. For example one can use a control condition with a significantly reduced number of modifications such as a cell line for which a modification writing enzyme was knocked-down or knocked-out. Alternatively, on a smaller scale transcripts of interests could be synthesized in-vitro. Nanocompore Nanocompore RNA modifications detection by comparative Nanopore direct RNA sequencing.RNA modifications detection from Nanopore dRNA-Seq data.Nanocompore identifies differences in ONT nanopore sequencing raw signal corresponding to RNA modifications by comparing 2 samples.Analyses performed for the nanocompore paper.Nanocompore compares 2 ONT nanopore direct RNA sequencing datasets from different experimental conditions expected to have a significant impact on RNA modifications. It is recommended to have at least 2 replicates per condition. For example one can use a control condition with a significantly reduced number of modifications such as a cell line for which a modification writing enzyme was knocked-down or knocked-out. Alternatively, on a smaller scale transcripts of interests could be synthesized in-vitro Post-translation modification site prediction, PolyA signal detection, Genotyping, k-mer counting Functional, regulatory and non-coding RNA, RNA-Seq, Gene transcripts, Transcriptomics, Transcription factors and regulatory sites To update https://nanocompore.rna.rocks/ Sequence Analysis nanocompore iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nanocompore 1.0.0rc3.post2 nanocompore 1.0.4 (0/2) (1/2) (2/2) True True -nanoplot 63235.0 2195.0 nanoplot Plotting tool for long read sequencing data and alignments To update https://github.com/wdecoster/NanoPlot Visualization nanoplot iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nanoplot/ 1.41.0 nanoplot 1.42.0 (1/1) (1/1) (1/1) True True -nanopolishcomp nanopolishcomp_eventaligncollapse, nanopolishcomp_freqmethcalculate NanopolishComp contains 2 modules. Eventalign_collapse collapses the raw file generated by nanopolish eventalign by kmers rather than by event. Freq_meth_calculate methylation frequency at genomic CpG sites from the output of nanopolish call-methylation. To update https://a-slide.github.io/NanopolishComp Sequence Analysis nanopolishcomp iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nanopolishcomp 0.6.11 nanopolishcomp 0.6.12 (0/2) (0/2) (2/2) True True -ncbi_fcs_gx ncbi_fcs_gx FCS-GX detects contamination from foreign organisms in genome sequences using the genome cross-species aligner (GX). Up-to-date https://github.com/ncbi/fcs-gx Sequence Analysis ncbi_fcs_gx iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/ncbi_fcs_gx 0.5.0 ncbi-fcs-gx 0.5.0 (1/1) (0/1) (0/1) False -necat 667.0 95.0 necat Error correction and de-novo assembly for ONT Nanopore reads necat NECAT NECAT is an error correction and de-novo assembly tool for Nanopore long noisy reads. De-novo assembly Sequence assembly Up-to-date https://github.com/xiaochuanle/NECAT Assembly necat iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/necat 0.0.1_update20200803 necat 0.0.1_update20200803 (0/1) (0/1) (1/1) True False -newick_utils 25505.0 448.0 newick_display Perform operations on Newick trees newick_utilities Newick Utilities The Newick Utilities are a set of command-line tools for processing phylogenetic trees. They can process arbitrarily large amounts of data and do not require user interaction, which makes them suitable for automating phylogeny processing tasks. Phylogenetic tree generation, Phylogenetic tree analysis, Phylogenetic tree reconstruction Phylogeny, Genomics, Computer science To update http://cegg.unige.ch/newick_utils Visualization, Metagenomics newick_utils iuc https://github.com/tjunier/newick_utils 1.6+galaxy1 newick_utils 1.6 (1/1) (1/1) (1/1) True True -nextclade 3527.0 169.0 nextalign, nextclade Identify differences between your sequences and a reference sequence used by Nextstrain To update https://github.com/nextstrain/nextclade Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nextclade 2.7.0 nextalign 2.14.0 (1/2) (1/2) (2/2) True True -nonpareil 142.0 5.0 nonpareil Estimate average coverage in metagenomic datasets To update http://nonpareil.readthedocs.io Metagenomics nonpareil iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nonpareil 3.1.1 nonpareil 3.4.1 (1/1) (0/1) (1/1) True True -novoplasty 6384.0 162.0 novoplasty NOVOPlasty is a de novo assembler and heteroplasmy/variance caller for short circular genomes. To update https://github.com/ndierckx/NOVOPlasty Assembly novoplasty iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/novoplasty 4.3.1 novoplasty 4.3.5 (0/1) (1/1) (1/1) True False -nugen_nudup nugen_nudup Marks/removes PCR introduced duplicate molecules based on the molecular tagging technology used in NuGEN products. Up-to-date http://nugentechnologies.github.io/nudup/ SAM, Metagenomics, Sequence Analysis, Transcriptomics nugen_nudup iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nugen_nudup 2.3.3 nudup 2.3.3 (0/1) (0/1) (0/1) True True -obitools obi_illumina_pairend, obi_ngsfilter, obi_annotate, obi_clean, obi_convert, obi_grep, obi_sort, obi_stat, obi_tab, obi_uniq OBITools is a set of programs developed to simplify the manipulation of sequence files obitools OBITools Set of python programs developed to simplify the manipulation of sequence files. They were mainly designed to help us for analyzing Next Generation Sequencer outputs (454 or Illumina) in the context of DNA Metabarcoding. Sequence analysis, Sequence analysis Sequence analysis, DNA, Sequencing Up-to-date http://metabarcoding.org/obitools Sequence Analysis obitools iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/obitools 1.2.13 obitools 1.2.13 (0/10) (10/10) (10/10) True False -odgi odgi_build, odgi_viz Representing large genomic variation graphs with minimal memory overhead requires a careful encoding of the graph entities. odgi follows the dynamic GBWT in developing a byte-packed version of the graph and paths through it. To update https://github.com/vgteam/odgi Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/odgi/ 0.3 odgi 0.8.4 (0/2) (0/2) (2/2) True False -omark omark Proteome quality assessment software To update https://github.com/DessimozLab/OMArk Sequence Analysis omark iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/omark/ 0.3.0 (0/1) (0/1) (0/1) False -ont_fast5_api ont_fast5_api_compress_fast5, ont_fast5_api_fast5_subset, ont_fast5_api_multi_to_single_fast5, ont_fast5_api_single_to_multi_fast5 ont_fast5_api is a simple interface to HDF5 files of the Oxford Nanopore FAST5 file format. To update https://github.com/nanoporetech/ont_fast5_api/ Nanopore ont_fast5_api iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ont_fast5_api 3.1.3 ont-fast5-api 4.1.3 (0/4) (0/4) (4/4) True False -optitype 321.0 24.0 optitype Precision HLA typing from NGS data Up-to-date https://github.com/FRED-2/OptiType Sequence Analysis optitype iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/optitype1 1.3.5 optitype 1.3.5 (0/1) (0/1) (1/1) True False -orfipy 774.0 53.0 orfipy Galaxy wrapper for ORFIPY orfipy orfipy A fast and flexible tool for extracting ORFs.orfipy is a tool written in python/cython to extract ORFs in extremely an fast and flexible manner. Other popular ORF searching tools are OrfM and getorf. Compared to OrfM and getorf, orfipy provides the most options to fine tune ORF searches. orfipy uses multiple CPU cores and is particularly faster for data containing multiple smaller fasta sequences such as de-novo transcriptome assemblies. Please read the preprint here. Coding region prediction, Database search, Transcriptome assembly, De-novo assembly Computer science, RNA-Seq, Transcriptomics, Small molecules Up-to-date https://github.com/urmi-21/orfipy Sequence Analysis orfipy iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/orfipy 0.0.4 orfipy 0.0.4 (1/1) (0/1) (1/1) True True -orthofinder orthofinder_onlygroups Accurate inference of orthologous gene groups made easy OrthoFinder OrthoFinder OrthoFinder is a fast, accurate and comprehensive platform for comparative genomics. It finds orthogroups and orthologs, infers rooted gene trees for all orthogroups and identifies all of the gene duplcation events in those gene trees. It also infers a rooted species tree for the species being analysed and maps the gene duplication events from the gene trees to branches in the species tree. OrthoFinder also provides comprehensive statistics for comparative genomic analyses. Genome comparison, Phylogenetic tree generation (from molecular sequences), Phylogenetic tree analysis, Genome alignment Phylogenetics, Phylogenomics, Bioinformatics, Comparative genomics, Sequence analysis Up-to-date https://github.com/davidemms/OrthoFinder Phylogenetics, Sequence Analysis orthofinder iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/orthofinder 2.5.5 orthofinder 2.5.5 (0/1) (1/1) (1/1) True True -pangolin 7276.0 259.0 pangolin Pangolin assigns SARS-CoV-2 genome sequences their most likely lineages under the Pango nomenclature system. Up-to-date https://github.com/cov-lineages/pangolin Sequence Analysis pangolin iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pangolin 4.3 pangolin 4.3 (1/1) (1/1) (1/1) True False -parse_mito_blast 90.0 31.0 parse_mito_blast Filtering blast out from querying assembly against mitochondrial database. Up-to-date https://raw.githubusercontent.com/VGP/vgp-assembly/master/galaxy_tools/parse_mito_blast/parse_mito_blast.py Sequence Analysis parse_mito_blast iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/parse_mito_blast 1.0.2 parse_mito_blast 1.0.2 (1/1) (1/1) (1/1) True False -pathview 5260.0 565.0 pathview Pathview is a tool set for pathway based data integration and visualization. pathview pathview Tool set for pathway based data integration and visualization that maps and renders a wide variety of biological data on relevant pathway graphs. It downloads the pathway graph data, parses the data file, maps user data to the pathway, and render pathway graph with the mapped data. In addition, it integrates with pathway and gene set (enrichment) analysis tools for large-scale and fully automated analysis. Pathway or network analysis, Pathway or network visualisation Molecular interactions, pathways and networks, Systems biology, Data visualisation To update https://bioconductor.org/packages/release/bioc/html/pathview.html Statistics, RNA, Micro-array Analysis pathview iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pathview 1.34.0 bioconductor-pathview 1.42.0 (1/1) (1/1) (1/1) True False + " To update https://funannotate.readthedocs.io Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/funannotate 1.8.15 (3/5) (5/5) (5/5) True True +gecko 519.0 112.0 gecko Ungapped genome comparison Up-to-date https://github.com/otorreno/gecko Sequence Analysis gecko iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gecko 1.2 gecko 1.2 (0/1) (1/1) (1/1) True False +gemini 1209.0 gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_db_info, gemini_@BINARY@, gemini_@BINARY@, gemini_inheritance, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@, gemini_@BINARY@ GEMINI: a flexible framework for exploring genome variation gemini GEMINI GEMINI (GEnome MINIng) is a flexible framework for exploring genetic variation in the context of the wealth of genome annotations available for the human genome. By placing genetic variants, sample phenotypes and genotypes, as well as genome annotations into an integrated database framework, GEMINI provides a simple, flexible, and powerful system for exploring genetic variation for disease and population genetics. Sequence analysis, Genetic variation analysis Sequence analysis To update https://github.com/arq5x/gemini Sequence Analysis, Next Gen Mappers gemini iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gemini 0.20.1 gemini 0.30.2 (1/3) (2/3) (2/3) True False +geneiobio 44.0 3.0 gene_iobio_display_generation_iframe Gene.iobio is an interactive tool for variant and trio analysis. To update https://github.com/iobio/gene.iobio Sequence Analysis geneiobio iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/geneiobio 4.7.1+galaxy1 (0/1) (1/1) (1/1) True False +genomic_super_signature 46.0 11.0 genomic_super_signature Interpretation of RNAseq experiments through robust, efficient comparison to public databases genomicsupersignature GenomicSuperSignature GenomicSuperSignature is a package for the interpretation of RNA-seq experiments through robust, efficient comparison to public databases. Gene-set enrichment analysis, Essential dynamics, Deposition, Principal component visualisation, Dimensionality reduction RNA-Seq, Transcriptomics, Microbial ecology, Genotype and phenotype, Microarray experiment To update https://github.com/shbrief/GenomicSuperSignature Sequence Analysis, RNA, Transcriptomics genomic_super_signature iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/genomic_super_signature 1.2.0 bioconductor-genomicsupersignature 1.10.0 (0/1) (0/1) (1/1) True False +getorganelle 495.0 18.0 get_annotated_regions_from_gb, get_organelle_from_reads GetOrganelle - This toolkit assembles organelle genomes from genomic skimming data. getorganelle GetOrganelle A fast and versatile toolkit for accurate de novo assembly of organelle genomes.This toolkit assemblies organelle genome from genomic skimming data. De-novo assembly, Genome assembly, Mapping assembly, Mapping, Sequence trimming Cell biology, Sequence assembly, Whole genome sequencing, Plant biology, Model organisms Up-to-date https://github.com/Kinggerm/GetOrganelle Assembly getorganelle iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/getorganelle 1.7.7.0 getorganelle 1.7.7.0 (0/2) (2/2) (2/2) True False +gff3_rebase 110.0 12.0 gff3.rebase Rebase a GFF against a parent GFF (e.g. an original genome) To update https://github.com/galaxyproject/tools-iuc/tree/master/tools/gff3_rebase Sequence Analysis gff3_rebase iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gff3_rebase 1.2 bcbiogff 0.6.6 (1/1) (1/1) (1/1) True False +gffread 10995.0 680.0 gffread gffread filters and/or converts GFF3/GTF2 records gffread gffread program for filtering, converting and manipulating GFF files Sequence annotation Nucleic acids, Sequence analysis Up-to-date http://ccb.jhu.edu/software/stringtie/gff.shtml#gffread/ Sequence Analysis gffread devteam https://github.com/galaxyproject/tools-iuc/tree/master/tools/gffread 0.12.7 gffread 0.12.7 (1/1) (1/1) (1/1) True False +ggplot2 ggplot2_heatmap, ggplot2_pca, ggplot2_histogram, ggplot2_point, ggplot2_violin ggplot2 is a system for declaratively creating graphics, based on The Grammar of Graphics.You provide the data, tell ggplot2 how to map variables to aesthetics, what graphical primitives to use,and it takes care of the details. ggplot2 ggplot2 Plotting system for R, based on the grammar of graphics. Visualisation Data visualisation To update https://github.com/tidyverse/ggplot2 Visualization iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ggplot2 3.4.0 r-base (5/5) (5/5) (5/5) True False +glimmer glimmer_acgt_content, glimmer_build_icm, glimmer_extract, glimmer_gbk_to_orf, glimmer_glimmer_to_gff, glimmer_long_orfs, glimmer_knowledge_based, glimmer_not_knowledge_based Glimmer makes gene predictions. gemini GEMINI GEMINI (GEnome MINIng) is a flexible framework for exploring genetic variation in the context of the wealth of genome annotations available for the human genome. By placing genetic variants, sample phenotypes and genotypes, as well as genome annotations into an integrated database framework, GEMINI provides a simple, flexible, and powerful system for exploring genetic variation for disease and population genetics. Sequence analysis, Genetic variation analysis Sequence analysis To update https://ccb.jhu.edu/software/glimmer/ Sequence Analysis bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/glimmer glimmer 3.02 (0/8) (0/8) (4/8) True True +goenrichment 5206.0 321.0 goenrichment, goslimmer Performs GO Enrichment analysis. goenrichment GOEnrichment GOEnrichment is a tool for performing GO enrichment analysis of gene sets, such as those obtained from RNA-seq or Microarray experiments, to help characterize them at the functional level. It is available in Galaxy Europe and as a stand-alone tool.GOEnrichment is flexible in that it allows the user to use any version of the Gene Ontology and any GO annotation file they desire. To enable the use of GO slims, it is accompanied by a sister tool GOSlimmer, which can convert annotation files from full GO to any specified GO slim.The tool features an optional graph clustering algorithm to reduce the redundancy in the set of enriched GO terms and simplify its output.It was developed by the BioData.pt / ELIXIR-PT team at the Instituto Gulbenkian de Ciência. Gene-set enrichment analysis Transcriptomics Up-to-date https://github.com/DanFaria/GOEnrichment Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/goenrichment 2.0.1 goenrichment 2.0.1 (2/2) (2/2) (2/2) True True +goseq 19167.0 1210.0 goseq goseq does selection-unbiased testing for category enrichment amongst differentially expressed (DE) genes for RNA-seq data goseq GOseq Detect Gene Ontology and/or other user defined categories which are over/under represented in RNA-seq data. Gene functional annotation RNA-Seq To update https://bioconductor.org/packages/release/bioc/html/goseq.html Statistics, RNA, Micro-array Analysis goseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/goseq 1.50.0 bioconductor-goseq 1.54.0 (1/1) (1/1) (1/1) True True +graphlan 5002.0 247.0 graphlan, graphlan_annotate GraPhlAn is a software tool for producing high-quality circular representations of taxonomic and phylogenetic trees graphlan GraPhlAn GraPhlAn is a software tool for producing high-quality circular representations of taxonomic and phylogenetic trees. GraPhlAn focuses on concise, integrative, informative, and publication-ready representations of phylogenetically- and taxonomically-driven investigation. Phylogenetic inference, Phylogenetic tree visualisation, Phylogenetic tree editing, Taxonomic classification Metagenomics, Phylogenetics, Phylogenomics, Cladistics To update https://github.com/biobakery/graphlan Metagenomics, Graphics, Phylogenetics graphlan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/humann2/ graphlan 1.1.3 (2/2) (2/2) (2/2) True True +gtdbtk gtdbtk_classify_wf GTDB-Tk is a software tool kit for assigning objective taxonomic classifications to bacterial and archaeal genomesbased on the Genome Database Taxonomy GTDB. It is designed to work with recent advances that allow hundreds orthousands of metagenome-assembled genomes (MAGs) to be obtained directly from environmental samples. It can alsobe applied to isolate and single-cell genomes. GTDB-Tk GTDB-Tk a toolkit to classify genomes with the Genome Taxonomy Database.GTDB-Tk: a toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes.GTDB-Tk is a software toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes based on the Genome Database Taxonomy GTDB. It is designed to work with recent advances that allow hundreds or thousands of metagenome-assembled genomes (MAGs) to be obtained directly from environmental samples. It can also be applied to isolate and single-cell genomes. The GTDB-Tk is open source and released under the GNU General Public License (Version 3). Genome alignment, Taxonomic classification, Sequence assembly, Query and retrieval Metagenomics, Taxonomy, Phylogenetics, Database management, Proteins To update https://github.com/Ecogenomics/GTDBTk Metagenomics gtdbtk iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gtdbtk 2.2.2 gtdbtk 2.3.2 (0/1) (1/1) (0/1) True True +gubbins 3340.0 145.0 gubbins Gubbins - bacterial recombination detection gubbins Gubbins Gubbins is a tool for rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences. Genotyping, Phylogenetic inference, Ancestral reconstruction Phylogeny, Genotype and phenotype, Whole genome sequencing To update Sequence Analysis gubbins iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/gubbins 3.2.1 gubbins 3.3.3 (1/1) (1/1) (1/1) True True +gwastools gwastools_manhattan_plot gwastools GWASTools Classes for storing very large GWAS data sets and annotation, and functions for GWAS data cleaning and analysis. Deposition, Analysis, Annotation GWAS study To update https://bioconductor.org/packages/release/bioc/html/GWASTools.html Visualization, Variant Analysis iuc 0.1.0 bioconductor-gwastools 1.48.0 (0/1) (0/1) (0/1) True False +hamronization hamronize_summarize, hamronize_tool Convert AMR gene detection tool output to hAMRonization specification format. hamronization hAMRonization Parse multiple Antimicrobial Resistance Analysis Reports into a common data structure Data handling, Antimicrobial resistance prediction, Parsing Public health and epidemiology, Microbiology, Bioinformatics To update https://github.com/pha4ge/hAMRonization Sequence Analysis hamronization iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hamronization 1.0.3 hamronization 1.1.4 (0/2) (0/2) (2/2) True True +hansel bio_hansel Heidelberg and Enteritidis SNP Elucidation Biohansel BioHansel BioHansel is a tool for performing high-resolution genotyping of bacterial isolates by identifying phylogenetically informative single nucleotide polymorphisms (SNPs), also known as canonical SNPs, in whole genome sequencing (WGS) data. The application uses a fast k-mer matching algorithm to map pathogen WGS data to canonical SNPs contained in hierarchically structured schemas and assigns genotypes based on the detected SNP profile. Genotyping, SNP detection, Genome assembly Whole genome sequencing, DNA polymorphism, Genotype and phenotype, Infectious disease, Agricultural science Up-to-date https://github.com/phac-nml/bio_hansel Sequence Analysis bio_hansel iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hansel 2.6.1 bio_hansel 2.6.1 (1/1) (0/1) (1/1) True True +hapcut2 hapcut2 Robust and accurate haplotype assembly for diverse sequencing technologies hapcut2 HapCUT2 "HapCUT2 is a maximum-likelihood-based tool for assembling haplotypes from DNA sequence reads, designed to ""just work"" with excellent speed and accuracy across a range of long- and short-read sequencing technologies.The output is in Haplotype block format described here: https://github.com/vibansal/HapCUT2/blob/master/outputformat.md" Haplotype mapping, Variant classification Up-to-date https://github.com/vibansal/HapCUT2 Assembly hapcut2 galaxy-australia https://github.com/galaxyproject/tools-iuc 1.3.3 hapcut2 1.3.3 (0/1) (1/1) (0/1) True False +hapog 295.0 36.0 hapog Hapo-G - Haplotype-Aware Polishing of Genomes hapog Hapo-G Hapo-G is a tool that aims to improve the quality of genome assemblies by polishing the consensus with accurate reads. It capable of incorporating phasing information from high-quality reads (short or long-reads) to polish genome assemblies and in particular assemblies of diploid and heterozygous genomes. Genome assembly, Optimisation and refinement Sequence assembly, Genomics Up-to-date https://github.com/institut-de-genomique/HAPO-G Assembly hapog iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hapog 1.3.7 hapog 1.3.7 (0/1) (0/1) (1/1) True False +heatmap2 ggplot2_heatmap2 heatmap.2 function from the R gplots package To update https://github.com/cran/gplots Visualization ggplot2_heatmap2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/heatmap2 3.1.3.1 r-gplots 2.17.0 (1/1) (1/1) (1/1) True False +heinz 1186.0 242.0 heinz_bum, heinz, heinz_scoring, heinz_visualization An algorithm for identification of the optimal scoring subnetwork. bionet BioNet This package provides functions for the integrated analysis of protein-protein interaction networks and the detection of functional modules. Different datasets can be integrated into the network by assigning p-values of statistical tests to the nodes of the network. By fitting a beta-uniform mixture model and calculating scores from these p-values, overall scores of network regions can be calculated and an integer linear programming algorithm identifies the maximum scoring subnetwork. Protein interaction analysis Molecular interactions, pathways and networks, Protein interactions To update https://github.com/ls-cwi/heinz Transcriptomics, Visualization, Statistics heinz iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/heinz 1.0 bioconductor-bionet 1.62.0 (4/4) (4/4) (4/4) True False +hicexplorer hicexplorer_chicaggregatestatistic, hicexplorer_chicdifferentialtest, hicexplorer_chicexportdata, hicexplorer_chicplotviewpoint, hicexplorer_chicqualitycontrol, hicexplorer_chicsignificantinteractions, hicexplorer_chicviewpoint, hicexplorer_chicviewpointbackgroundmodel, hicexplorer_hicadjustmatrix, hicexplorer_hicaggregatecontacts, hicexplorer_hicaverageregions, hicexplorer_hicbuildmatrix, hicexplorer_hiccomparematrices, hicexplorer_hiccompartmentspolarization, hicexplorer_hicconvertformat, hicexplorer_hiccorrectmatrix, hicexplorer_hiccorrelate, hicexplorer_hicdetectloops, hicexplorer_hicdifferentialtad, hicexplorer_hicfindrestrictionsites, hicexplorer_hicfindtads, hicexplorer_hichyperoptDetectLoops, hicexplorer_hicinfo, hicexplorer_hicinterintratad, hicexplorer_hicmergedomains, hicexplorer_hicmergeloops, hicexplorer_hicmergematrixbins, hicexplorer_hicnormalize, hicexplorer_hicpca, hicexplorer_hicplotaverageregions, hicexplorer_hicplotdistvscounts, hicexplorer_hicplotmatrix, hicexplorer_hicplotsvl, hicexplorer_hicplotviewpoint, hicexplorer_hicquickqc, hicexplorer_hicsummatrices, hicexplorer_hictadclassifier, hicexplorer_hictraintadclassifier, hicexplorer_hictransform, hicexplorer_hicvalidatelocations HiCExplorer: Set of programs to process, analyze and visualize Hi-C data. To update https://github.com/deeptools/HiCExplorer Sequence Analysis, Visualization hicexplorer bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/hicexplorer 3.7.2 hicexplorer 3.7.3 (0/40) (5/40) (40/40) True False +hicstuff hicstuff_pipeline To update https://github.com/koszullab/hicstuff Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hicstuff 3.1.5 hicstuff 3.2.2 (0/1) (0/1) (0/1) True False +hifiasm_meta 137.0 12.0 hifiasm_meta A hifiasm fork for metagenome assembly using Hifi reads. hifiasm-meta Hifiasm-meta Hifiasm_meta - de novo metagenome assembler, based on hifiasm, a haplotype-resolved de novo assembler for PacBio Hifi reads. Sequence assembly Sequence assembly, Metagenomics To update https://github.com/xfengnefx/hifiasm-meta Metagenomics hifiasm_meta galaxy-australia https://github.com/galaxyproject/tools-iuc/tree/master/tools/hifiasm_meta 0.3.1 hifiasm_meta hamtv0.3.1 (0/1) (1/1) (1/1) True True +hisat2 299104.0 4183.0 hisat2 HISAT2 is a fast and sensitive spliced alignment program. hisat2 HISAT2 Alignment program for mapping next-generation sequencing reads (both DNA and RNA) to a population of human genomes (as well as to a single reference genome). Sequence alignment RNA-seq Up-to-date http://ccb.jhu.edu/software/hisat2/ Assembly hisat2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hisat2 2.2.1 hisat2 2.2.1 (1/1) (1/1) (1/1) True False +hmmer3 21049.0 111.0 hmmer_alimask, hmmer_hmmalign, hmmer_hmmbuild, hmmer_hmmconvert, hmmer_hmmemit, hmmer_hmmfetch, hmmer_hmmscan, hmmer_hmmsearch, hmmer_jackhmmer, hmmer_nhmmer, hmmer_nhmmscan, hmmer_phmmer HMMER is used for searching sequence databases for homologs of proteinsequences, and for making protein sequence alignments. It implementsmethods using probabilistic models called profile hidden Markov models(profile HMMs). hmmer3 HMMER3 This tool is used for searching sequence databases for homologs of protein sequences, and for making protein sequence alignments. It implements methods using probabilistic models called profile hidden Markov models. The new HMMER3 project, HMMER is now as fast as BLAST for protein search. Formatting, Multiple sequence alignment, Sequence profile generation, Format validation, Conversion, Sequence generation, Data retrieval, Statistical calculation, Database search, Formatting, Database search, Database search, Probabilistic sequence generation, Statistical calculation, Statistical calculation, Sequence database search, Formatting, Sequence database search, Database search, Sequence database search Sequence analysis, Sequence sites, features and motifs, Gene and protein families Up-to-date http://hmmer.org/ Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 3.4 hmmer 3.4 (0/12) (12/12) (12/12) True True +homer homer_annotatePeaks, homer_findMotifs, homer_findMotifsGenome, homer_gtf_to_annotations, homer_scanMotifGenomeWide HOMER (Hypergeometric Optimization of Motif EnRichment) is a suite of tools for Motif Discovery and next-gen sequencing analysis. homer homer HOMER contains a novel motif discovery algorithm that was designed for regulatory element analysis in genomics applications (DNA only, no protein). It is a differential motif discovery algorithm, which means that it takes two sets of sequences and tries to identify the regulatory elements that are specifically enriched in on set relative to the other. It uses ZOOPS scoring (zero or one occurrence per sequence) coupled with the hypergeometric enrichment calculations (or binomial) to determine motif enrichment. HOMER also tries its best to account for sequenced bias in the dataset. It was designed with ChIP-Seq and promoter analysis in mind, but can be applied to pretty much any nucleic acids motif finding problem. Sequence motif discovery Up-to-date http://homer.ucsd.edu/homer/index.html Sequence Analysis data_manager_homer_preparse iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/homer 4.11 homer 4.11 (0/5) (0/5) (5/5) True False +htseq_count 154533.0 1419.0 htseq_count Count aligned reads (SAM/BAM) that overlap genomic features (GFF) htseq HTSeq Python framework to process and analyse high-throughput sequencing (HTS) data Nucleic acid sequence analysis Sequence analysis Up-to-date https://readthedocs.org/projects/htseq/ Genomic Interval Operations, SAM, Sequence Analysis, RNA htseq_count lparsons https://github.com/galaxyproject/tools-iuc/tree/master/tools/htseq_count 2.0.5 htseq 2.0.5 (1/1) (1/1) (1/1) True False +humann 5856.0 247.0 humann, humann_associate, humann_barplot, humann_join_tables, humann_reduce_table, humann_regroup_table, humann_rename_table, humann_renorm_table, humann_rna_dna_norm, humann_split_stratified_table, humann_split_table, humann_strain_profiler, humann_unpack_pathways HUMAnN for functionally profiling metagenomes and metatranscriptomes at species-level resolution humann humann HUMAnN is a pipeline for efficiently and accurately profiling the presence/absence and abundance of microbial pathways in a community from metagenomic or metatranscriptomic sequencing data (typically millions of short DNA/RNA reads). This process, referred to as functional profiling, aims to describe the metabolic potential of a microbial community and its members. More generally, functional profiling answers the question “What are the microbes in my community-of-interest doing (or are capable of doing)?” Species frequency estimation, Taxonomic classification, Phylogenetic analysis Metagenomics, Phylogenomics Up-to-date http://huttenhower.sph.harvard.edu/humann Metagenomics humann iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/humann 3.8 humann 3.8 (6/13) (12/13) (13/13) True True +hybpiper hybpiper Analyse targeted sequence capture data HybPiper HybPiper Paralogs and off-target sequences improve phylogenetic resolution in a densely-sampled study of the breadfruit genus (Artocarpus, Moraceae).Recovering genes from targeted sequence capture data.Current version: 1.3.1 (August 2018).-- Read our article in Applications in Plant Sciences (Open Access).HybPiper was designed for targeted sequence capture, in which DNA sequencing libraries are enriched for gene regions of interest, especially for phylogenetics. HybPiper is a suite of Python scripts that wrap and connect bioinformatics tools in order to extract target sequences from high-throughput DNA sequencing reads. Sequence trimming, Sequence assembly, Read mapping Phylogenetics, Plant biology, Gene transcripts, Sequence assembly, Phylogenomics Up-to-date https://github.com/mossmatters/HybPiper Sequence Analysis, Phylogenetics hybpiper iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hybpiper 2.1.6 hybpiper 2.1.6 (0/1) (1/1) (0/1) True False +hyphy hyphy_absrel, hyphy_annotate, hyphy_bgm, hyphy_busted, hyphy_cfel, hyphy_conv, hyphy_fade, hyphy_fel, hyphy_fubar, hyphy_gard, hyphy_meme, hyphy_prime, hyphy_relax, hyphy_slac, hyphy_sm19, hyphy_strike_ambigs, hyphy_summary Hypothesis Testing using Phylogenies HyPhy HyPhy Software package for the analysis of genetic sequences using techniques in phylogenetics, molecular evolution, and machine learning. Statistical calculation Phylogeny, Small molecules, Molecular interactions, pathways and networks To update http://www.hyphy.org Phylogenetics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ 2.5.47 hyphy 2.5.59 (17/17) (2/17) (17/17) True True +hypo 354.0 39.0 hypo Super Fast & Accurate Polisher for Long Read Genome Assemblies HyPo HyPo HyPo, a Hybrid Polisher, utilizes short as well as long reads within a single run to polish a long reads assembly of small and large genomes. Optimisation and refinement, Genome assembly Sequence assembly, Genomics Up-to-date https://github.com/kensung-lab/hypo Assembly hypo iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/hypo 1.0.3 hypo 1.0.3 (0/1) (0/1) (1/1) True True +icescreen icescreen ICEscreen identifies Integrative Conjugative Elements (ICEs) and Integrative Mobilizable Elements (IMEs) in Bacillota genomes. icescreen ICEscreen A tool to detect Firmicute ICEs and IMEs, isolated or enclosed in composite structures. Database search, Protein feature detection Mobile genetic elements, Sequence sites, features and motifs, Genomics, Molecular interactions, pathways and networks, Structural variation To update https://icescreen.migale.inrae.fr/ Genome annotation icescreen iuc https://forgemia.inra.fr/ices_imes_analysis/icescreen 1.3.1 icescreen 1.3.2 (0/1) (0/1) (0/1) True True +idba_ud 721.0 43.0 idba_hybrid, idba_tran, idba_ud Wrappers for the idba assembler variants. idba IDBA A short read assembler based on iterative De Bruijn graph. It is developed under 64-bit Linux, but should be suitable for all unix-like system. Sequence assembly Sequence assembly To update https://i.cs.hku.hk/~alse/hkubrg/projects/index.html Assembly idba iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/idba_ud idba 1.1.3 (3/3) (0/3) (3/3) True True +idr 2873.0 30.0 idr Galaxy wrappers for the IDR package from Nathan Boleu To update https://github.com/nboley/idr Sequence Analysis idr iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/idr/ 2.0.3 idr 2.0.4.2 (1/1) (0/1) (1/1) True False +iedb_api 1506.0 12.0 iedb_api Get epitope binding predictions from IEDB-API To update http://tools.immuneepitope.org/main/tools-api/ Data Source, Sequence Analysis iedb_api iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/iedb_api 2.15.2 python (0/1) (0/1) (1/1) True False +instrain instrain_compare, instrain_profile InStrain is a tool for analysis of co-occurring genome populations from metagenomes instrain InStrain InStrain is a tool for analysis of co-occurring genome populations from metagenomes that allows highly accurate genome comparisons, analysis of coverage, microdiversity, and linkage, and sensitive SNP detection with gene localization and synonymous non-synonymous identification SNP detection, Genome comparison Mapping, Metagenomics To update https://instrain.readthedocs.io/en/latest/# Metagenomics instrain iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/instrain 1.5.3 instrain 1.8.0 (0/2) (0/2) (2/2) True True +integron_finder 52965.0 58.0 integron_finder """IntegronFinder identify integrons with high accuracy and sensitivity.It searches for attC sites using covariance models, for integron-integrases using HMM profiles, and for other features (promoters, attI site) using pattern matching""" integron_finder Integron Finder A tool to detect Integron in DNA sequences. Nucleic acid feature detection, Sequence motif recognition, Protein feature detection, Genome annotation Functional genomics, Mobile genetic elements, Molecular biology, Sequence analysis Up-to-date https://github.com/gem-pasteur/Integron_Finder Sequence Analysis integronfinder iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/integron_finder 2.0.3 integron_finder 2.0.3 (0/1) (1/1) (1/1) True False +interproscan 5294.0 554.0 interproscan Interproscan queries the interpro database and provides annotations. interproscan_ebi InterProScan (EBI) Scan sequences against the InterPro protein signature databases. Sequence motif recognition, Protein feature detection Gene and protein families, Sequence analysis To update http://www.ebi.ac.uk/Tools/pfa/iprscan5/ Sequence Analysis interproscan bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/interproscan 5.59-91.0 interproscan 5.59_91.0 (1/1) (1/1) (1/1) True True +iqtree 21598.0 681.0 iqtree Efficient phylogenomic software by maximum likelihood To update http://www.iqtree.org/ Phylogenetics iqtree iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/iqtree/ 2.1.2 iqtree 2.2.6 (1/1) (1/1) (1/1) True True +isescan 57581.0 50.0 isescan """ISEScan is a pipeline to identify IS (Insertion Sequence) elements in genome and metagenomebased on profile hidden Markov models constructed from manually curated IS elements.""" ISEScan ISEScan Automated identification of insertion sequence elements in prokaryotic genomes. Structural variation detection Genomics, DNA structural variation, Sequence analysis, Genetic variation To update https://github.com/xiezhq/ISEScan Sequence Analysis ISEScan iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/isescan 1.7.2.3 isescan 1.7.2.1 (0/1) (1/1) (1/1) True False +isoformswitchanalyzer 822.0 29.0 isoformswitchanalyzer Statistical identification of isoform switching from RNA-seq derived quantification of novel and/or annotated full-length isoforms. IsoformSwitchAnalyzeR IsoformSwitchAnalyzeR Enables identification of isoform switches with predicted functional consequences from RNA-seq data. Consequences can be chosen from a long list but includes protein domains gain/loss changes in NMD sensitivity etc. It directly supports import of data from Cufflinks/Cuffdiff, Kallisto, Salmon and RSEM but other transcript qunatification tools are easy to import as well. Sequence comparison, Sequence analysis Computational biology, Gene transcripts To update https://bioconductor.org/packages/devel/bioc/html/IsoformSwitchAnalyzeR.html Transcriptomics, RNA, Statistics isoformswitchanalyzer iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/isoformswitchanalyzer 1.20.0 bioconductor-isoformswitchanalyzer 2.2.0 (1/1) (1/1) (1/1) True False +ivar ivar_consensus, ivar_filtervariants, ivar_removereads, ivar_trim, ivar_variants iVar is a computational package that contains functions broadly useful for viral amplicon-based sequencing Up-to-date https://github.com/andersen-lab/ivar Sequence Analysis ivar iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ivar/ 1.4.2 ivar 1.4.2 (5/5) (5/5) (5/5) True True +jbrowse 18229.0 2346.0 jbrowse_to_standalone, jbrowse JBrowse Genome Browser integrated as a Galaxy Tool jbrowse JBrowse Slick, speedy genome browser with a responsive and dynamic AJAX interface for visualization of genome data. Being developed by the GMOD project as a successor to GBrowse. Genome visualisation Genomics Up-to-date https://jbrowse.org Sequence Analysis jbrowse iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/jbrowse 1.16.11 jbrowse 1.16.11 (2/2) (2/2) (2/2) True True +jcvi_gff_stats 2469.0 255.0 jcvi_gff_stats Compute statistics from a genome annotation in GFF3 format (using JCVI Python utilities) To update https://github.com/tanghaibao/jcvi Sequence Analysis jcvi_gff_stats iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/jcvi_gff_stats 0.8.4 jcvi 1.3.9 (1/1) (1/1) (1/1) True False +jellyfish 1138.0 91.0 jellyfish Jellyfish is a tool for fast, memory-efficient counting of k-mers in DNA Jellyfish Jellyfish A command-line algorithm for counting k-mers in DNA sequence. k-mer counting Sequence analysis, Genomics To update https://github.com/gmarcais/Jellyfish Assembly jellyfish iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/jellyfish kmer-jellyfish 2.3.1 (0/1) (1/1) (1/1) True True +kc-align kc-align Kc-Align custom tool kc-align kc-align A fast and accurate tool for performing codon-aware multiple sequence alignments Multiple sequence alignment Mapping Up-to-date https://github.com/davebx/kc-align Sequence Analysis kc_align iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/kc-align 1.0.2 kcalign 1.0.2 (1/1) (0/1) (1/1) True True +khmer khmer_abundance_distribution_single, khmer_abundance_distribution, khmer_count_median, khmer_partition, khmer_extract_partitions, khmer_filter_abundance, khmer_filter_below_abundance_cutoff, khmer_normalize_by_median In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more khmer khmer khmer is a set of command-line tools for working with DNA shotgun sequencing data from genomes, transcriptomes, metagenomes, and single cells. khmer can make de novo assemblies faster, and sometimes better. khmer can also identify (and fix) problems with shotgun data. Standardisation and normalisation, De-novo assembly Sequence assembly Up-to-date https://khmer.readthedocs.org/ Assembly, Next Gen Mappers khmer iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/khmer 3.0.0a3 khmer 3.0.0a3 (8/8) (8/8) (8/8) True True +kleborate 319.0 38.0 kleborate Screen genome assemblies of Klebsiella pneumoniae and the Klebsiella pneumoniae species complex (KpSC) kleborate Kleborate Genomic surveillance framework and global population structure for Klebsiella pneumoniae.Kleborate is a tool to screen genome assemblies of Klebsiella pneumoniae and the Klebsiella pneumoniae species complex (KpSC) for:.A manuscript describing the Kleborate software in full is currently in preparation. In the meantime, if you use Kleborate, please cite the preprint: Lam, MMC. et al. Genomic surveillance framework and global population structure for Klebsiella pneumoniae. bioRxiv (2020). Multilocus sequence typing, Genome assembly, Virulence prediction Public health and epidemiology, Metagenomics, Population genomics, Sequence assembly, Whole genome sequencing Up-to-date https://github.com/katholt/Kleborate/wiki Metagenomics kleborate iuc https://github.com/katholt/Kleborate 2.3.2 kleborate 2.3.2 (0/1) (0/1) (1/1) True True +kofamscan 594.0 33.0 kofamscan Gene function annotation tool based on KEGG Orthology and hidden Markov model Up-to-date https://github.com/takaram/kofam_scan Sequence Analysis kofamscan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/kofamscan 1.3.0 kofamscan 1.3.0 (0/1) (0/1) (1/1) True True +kraken_biom 1444.0 182.0 kraken_biom Create BIOM-format tables (http://biom-format.org) from Kraken output (http://ccb.jhu.edu/software/kraken/) Up-to-date https://github.com/smdabdoub/kraken-biom Metagenomics kraken_biom iuc https://github.com/smdabdoub/kraken-biom 1.2.0 kraken-biom 1.2.0 (0/1) (1/1) (1/1) True True +kraken_taxonomy_report 2527.0 354.0 kraken_taxonomy_report Kraken taxonomy report To update https://github.com/blankenberg/Kraken-Taxonomy-Report Metagenomics kraken_taxonomy_report iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/kraken_taxonomy_report 0.0.3 biopython 1.70 (1/1) (1/1) (1/1) True True +krakentools krakentools_alpha_diversity, krakentools_beta_diversity, krakentools_combine_kreports, krakentools_extract_kraken_reads, krakentools_kreport2krona, krakentools_kreport2mpa KrakenTools is a suite of scripts to be used alongside the Kraken krakentools KrakenTools KrakenTools provides individual scripts to analyze Kraken/Kraken2/Bracken/KrakenUniq output files Visualisation, Aggregation Taxonomy, Metagenomics Up-to-date https://github.com/jenniferlu717/KrakenTools Metagenomics krakentools iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/krakentools 1.2 krakentools 1.2 (1/6) (6/6) (6/6) True True +krocus krocus Predict MLST directly from uncorrected long reads To update https://github.com/quadram-institute-bioscience/krocus Sequence Analysis krocus iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/krocus 1.0.1 krocus 1.0.3 (0/1) (0/1) (0/1) True True +last 227.0 41.0 last_al, last_db, last_split, last_train, last_maf_convert LAST finds similar regions between sequences. last LAST Short read alignment program incorporating quality scores Sequence alignment Genomics, Comparative genomics To update http://last.cbrc.jp/ Sequence Analysis last iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/last 1205 last 1542 (0/5) (0/5) (5/5) True False +legsta 55.0 7.0 legsta Performs in silico Legionella pneumophila sequence based typing. Up-to-date https://github.com/tseemann/legsta Sequence Analysis legsta iuc https://github.com/tseemann/legsta 0.5.1 legsta 0.5.1 (0/1) (0/1) (1/1) True True +length_and_gc_content 4090.0 322.0 length_and_gc_content Gets gene length and gc content from a fasta and a GTF file To update https://github.com/galaxyproject/tools-iuc/tree/master/tools/length_and_gc_content Fasta Manipulation, Statistics, RNA, Micro-array Analysis length_and_gc_content iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/length_and_gc_content 0.1.2 r-optparse 1.3.2 (1/1) (1/1) (1/1) True False +limma_voom 20344.0 1012.0 limma_voom Perform RNA-Seq differential expression analysis using limma voom pipeline limma limma Data analysis, linear models and differential expression for microarray data. RNA-Seq analysis Molecular biology, Genetics Up-to-date http://bioconductor.org/packages/release/bioc/html/limma.html Transcriptomics, RNA, Statistics limma_voom iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/limma_voom 3.58.1 bioconductor-limma 3.58.1 (1/1) (1/1) (1/1) True False +lineagespot 37.0 2.0 lineagespot Identification of SARS-CoV-2 related metagenomic mutations based on a single (or a list of) variant(s) file(s) lineagespot lineagespot Lineagespot is a framework written in R, and aims to identify and assign different SARS-CoV-2 lineages based on a single variant file (i.e., variant calling format). Variant calling Metagenomics, Gene transcripts, Evolutionary biology, Sequencing, Genetic variation To update https://www.bioconductor.org/packages/release/bioc/html/lineagespot.html Metagenomics, Sequence Analysis lineagespot iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/lineagespot 1.6.0 r-base (0/1) (0/1) (1/1) True True +links 405.0 77.0 links Scaffold genome assemblies with long reads. links LINKS LINKS (Long Interval Nucleotide K-mer Scaffolder) is a genomics application for scaffolding genome assemblies with long reads, such as those produced by Oxford Nanopore Technologies Ltd. It can be used to scaffold high-quality draft genome assemblies with any long sequences (eg. ONT reads, PacBio reads, other draft genomes, etc). It is also used to scaffold contig pairs linked by ARCS/ARKS. Scaffolding, Genome assembly, Read mapping, Read pre-processing, Sequence trimming Sequence assembly, Mapping, Sequencing Up-to-date https://github.com/bcgsc/LINKS Assembly links iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/links 2.0.1 links 2.0.1 (0/1) (1/1) (1/1) True False +lorikeet lorikeet_spoligotype Tools for M. tuberculosis DNA fingerprinting (spoligotyping) Up-to-date https://github.com/AbeelLab/lorikeet Sequence Analysis lorikeet_spoligotype iuc https://github.com/AbeelLab/lorikeet 20 lorikeet 20 (0/1) (0/1) (1/1) True True +m6anet 3.0 m6anet m6anet to detect m6A RNA modifications from nanopore data m6Anet m6Anet Detection of m6A from direct RNA sequencing using a Multiple Instance Learning framework. Quantification, Imputation, Gene expression profiling RNA-Seq, Transcriptomics, RNA, Machine learning Up-to-date https://m6anet.readthedocs.io/en/latest Sequence Analysis m6anet iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/m6anet 2.1.0 m6anet 2.1.0 (0/1) (0/1) (1/1) True True +maaslin2 188.0 29.0 maaslin2 MaAsLin2 is comprehensive R package for efficiently determining multivariable association between microbial meta'omic features and clinical metadata. Up-to-date http://huttenhower.sph.harvard.edu/maaslin Metagenomics maaslin2 iuc https://github.com/biobakery/Maaslin2 0.99.12 maaslin2 0.99.12 (0/1) (0/1) (1/1) True True +macs2 84202.0 1968.0 macs2_bdgbroadcall, macs2_bdgcmp, macs2_bdgdiff, macs2_bdgpeakcall, macs2_callpeak, macs2_filterdup, macs2_predictd, macs2_randsample, macs2_refinepeak MACS - Model-based Analysis of ChIP-Seq macs MACS Model-based Analysis of ChIP-seq data. Peak calling, Enrichment analysis, Gene regulatory network analysis ChIP-seq, Molecular interactions, pathways and networks, Transcription factors and regulatory sites Up-to-date https://github.com/taoliu/MACS Sequence Analysis, Statistics macs2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/macs2 2.2.9.1 macs2 2.2.9.1 (9/9) (9/9) (9/9) True False +maker 4950.0 419.0 maker, maker_map_ids MAKER is a portable and easily configurable genome annotation pipeline.Its purpose is to allow smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. maker MAKER Portable and easily configurable genome annotation pipeline. It’s purpose is to allow smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. Genome annotation Genomics, DNA, Sequence analysis To update http://www.yandell-lab.org/software/maker.html Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/maker 2.31.11 maker 3.01.03 (2/2) (2/2) (2/2) True True +mapseq 167.0 2.0 mapseq fast and accurate sequence read classification tool designed to assign taxonomy and OTU classifications to ribosomal RNA sequences. To update https://github.com/jfmrod/MAPseq Metagenomics mapseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mapseq 2.1.1 perl (0/1) (0/1) (1/1) True True +mash 1739.0 12.0 mash_screen, mash_sketch Fast genome and metagenome distance estimation using MinHash mash Mash Fast genome and metagenome distance estimation using MinHash. Sequence distance matrix generation Genomics, Metagenomics, Statistics and probability, Sequence analysis, DNA mutation Up-to-date https://github.com/marbl/Mash Metagenomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mash 2.3 mash 2.3 (2/2) (2/2) (2/2) True True +mashmap mashmap Fast local alignment boundaries Up-to-date https://github.com/galaxyproject/tools-iuc/tree/master/tools/mashmap Sequence Analysis mashmap iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mashmap 3.1.3 mashmap 3.1.3 (0/1) (0/1) (0/1) False +masigpro 576.0 13.0 masigpro Identify significantly differential expression profiles in time-course microarray experiments masigpro maSigPro Regression based approach to find genes for which there are significant gene expression profile differences between experimental groups in time course microarray and RNA-Seq experiments. Regression analysis Gene expression, Molecular genetics, Microarray experiment, RNA-Seq To update https://www.bioconductor.org/packages/release/bioc/html/maSigPro.html Transcriptomics, RNA, Statistics masigpro iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/masigpro 1.49.3 coreutils 8.25 (1/1) (0/1) (1/1) True False +maxbin2 2059.0 118.0 maxbin2 clusters metagenomic contigs into bins maxbin MaxBin Software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm. Sequence assembly Metagenomics, Sequence assembly, Microbiology To update https://downloads.jbei.org/data/microbial_communities/MaxBin/MaxBin.html Metagenomics maxbin2 mbernt https://github.com/galaxyproject/tools-iuc/tree/master/tools/maxbin2/ maxbin2 2.2.7 (1/1) (1/1) (1/1) True True +mcl 29.0 10.0 mcl The Markov Cluster Algorithm, a cluster algorithm for graphs mcl MCL MCL is a clustering algorithm widely used in bioinformatics and gaining traction in other fields. Clustering, Network analysis, Gene regulatory network analysis Molecular interactions, pathways and networks Up-to-date https://micans.org/mcl/man/mcl.html Sequence Analysis mcl iuc https://github.com/galaxyproject/tools-iuc/tree/master/mcl 22.282 mcl 22.282 (0/1) (0/1) (1/1) True True +medaka medaka_consensus, medaka_consensus_pipeline, medaka_snp, medaka_variant Sequence correction provided by ONT Research medaka Medaka medaka is a tool to create consensus sequences and variant calls from nanopore sequencing data. This task is performed using neural networks applied a pileup of individual sequencing reads against a draft assembly. Base-calling, Variant calling, Sequence assembly Sequence assembly, Machine learning To update https://github.com/nanoporetech/medaka Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/medaka 1.7.2 medaka 1.11.3 (3/4) (3/4) (3/4) True True +megahit 9530.0 548.0 megahit An ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph. megahit MEGAHIT Single node assembler for large and complex metagenomics NGS reads, such as soil. It makes use of succinct de Bruijn graph to achieve low memory usage, whereas its goal is not to make memory usage as low as possible. Genome assembly Metagenomics, Sequencing, Ecology, Sequence assembly Up-to-date https://github.com/voutcn/megahit Sequence Analysis, Assembly, Metagenomics megahit iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/megahit 1.2.9 megahit 1.2.9 (1/1) (1/1) (1/1) True True +megahit_contig2fastg 475.0 54.0 megahit_contig2fastg A subprogram within the Megahit toolkit for converting contigs to assembly graphs (fastg) megahit MEGAHIT Single node assembler for large and complex metagenomics NGS reads, such as soil. It makes use of succinct de Bruijn graph to achieve low memory usage, whereas its goal is not to make memory usage as low as possible. Genome assembly Metagenomics, Sequencing, Ecology, Sequence assembly To update https://github.com/voutcn/megahit/blob/master/tools/toolkit.cpp Sequence Analysis, Assembly, Metagenomics megahit_contig2fastg iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/megahit_contig2fastg 1.1.3 megahit 1.2.9 (1/1) (0/1) (1/1) True True +megan megan_blast2lca, megan_blast2rma, megan_daa2info, megan_daa2rma, megan_daa_meganizer, megan_read_extractor, megan_sam2rma MEGAN Community Edition - Interactive exploration and analysis of large-scale microbiome sequencing data. MEGAN is a tool for studying the taxonomic content of a set of DNA reads, typically collected in a metagenomics project.In a preprocessing step, a sequence alignment of all reads against a suitable database of reference DNA or proteinsequences must be performed to produce an input file for the program. MEGAN is suitable for DNA reads (metagenomedata), RNA reads (metatranscriptome data), peptide sequences (metaproteomics data) and, using a suitable synonymsfile that maps SILVA ids to taxon ids, for 16S rRNA data (amplicon sequencing). megan MEGAN Metagenome Analysis Software - MEGAN (MEtaGenome ANalyzer) is a new computer program that allows laptop analysis of large metagenomic datasets. In a preprocessing step, the set of DNA reads (or contigs) is compared against databases of known sequences using BLAST or another comparison tool. MEGAN can then be used to compute and interactively explore the taxonomical content of the dataset, employing the NCBI taxonomy to summarize and order the results. Sequence analysis, Taxonomic classification Sequence analysis To update https://github.com/husonlab/megan-ce Sequence Analysis megan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/megan 6.21.7 megan 6.25.9 (0/7) (0/7) (7/7) True True +meningotype meningotype Assign sequence type to N. meningitidis genome assemblies Up-to-date https://github.com/MDU-PHL/meningotype Sequence Analysis meningotype iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/meningotype 0.8.5 meningotype 0.8.5 (0/1) (0/1) (0/1) True True +merqury 2483.0 244.0 merqury, merquryplot Merqury is a tool for evaluating genomes assemblies based of k-mer operations. merqury Merqury Reference-free quality, completeness, and phasing assessment for genome assemblies.Evaluate genome assemblies with k-mers and more.Often, genome assembly projects have illumina whole genome sequencing reads available for the assembled individual.Merqury provides a set of tools for this purpose. Genome assembly, k-mer counting, Scaffolding, Phasing, De-novo assembly Sequence assembly, Whole genome sequencing, Plant biology Up-to-date https://github.com/marbl/merqury Assembly merqury iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/merqury 1.3 merqury 1.3 (2/2) (2/2) (2/2) True True +meryl 6785.0 350.0 meryl Meryl a k-mer counter. meryl Meryl Meryl is a tool for counting and working with sets of k-mers that was originally developed for use in the Celera Assembler and has since been migrated and maintained as part of Canu. k-mer counting Whole genome sequencing, Genomics, Sequence analysis, Sequencing Up-to-date https://github.com/marbl/meryl Assembly meryl iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/meryl 1.3 merqury 1.3 (1/1) (1/1) (1/1) True True +metabat2 4072.0 154.0 metabat2_jgi_summarize_bam_contig_depths, metabat2 MetaBAT2 (Metagenome Binning based on Abundance and Tetranucleotide frequency) is an automated metagenome binningsoftware that integrates empirical probabilistic distances of genome abundance and tetranucleotide frequency. MetaBAT_2 MetaBAT 2 "an adaptive binning algorithm for robust and efficient genome reconstruction from metagenome assemblies | MetaBAT2 clusters metagenomic contigs into different ""bins"", each of which should correspond to a putative genome | MetaBAT2 uses nucleotide composition information and source strain abundance (measured by depth-of-coverage by aligning the reads to the contigs) to perform binning" Read binning, Sequence assembly, Genome annotation Metagenomics, Sequence assembly, Metagenomic sequencing Up-to-date https://bitbucket.org/berkeleylab/metabat/src/master/ Metagenomics metabat2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/metabat2/ 2.15 metabat2 2.15 (1/2) (1/2) (2/2) True True +metaeuk metaeuk_easy_predict MetaEuk is a modular toolkit designed for large-scale gene discovery andannotation in eukaryotic metagenomic contigs. Metaeuk combines the fast andsensitive homology search capabilities of MMseqs2 with a dynamic programmingprocedure to recover optimal exons sets. It reduces redundancies in multiplediscoveries of the same gene and resolves conflicting gene predictions onthe same strand. MetaEuk MetaEuk MetaEuk - sensitive, high-throughput gene discovery and annotation for large-scale eukaryotic metagenomics Homology-based gene prediction Metagenomics, Gene and protein families To update https://github.com/soedinglab/metaeuk Sequence Analysis, Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/metaeuk 5.34c21f2 metaeuk 6.a5d39d9 (0/1) (0/1) (1/1) True True +metagenomeseq metagenomeseq_normalizaton metagenomeSeq Normalization metagenomeseq metagenomeSeq Designed to determine features (be it Operational Taxanomic Unit (OTU), species, etc.) that are differentially abundant between two or more groups of multiple samples. It is designed to address the effects of both normalization and under-sampling of microbial communities on disease association detection and the testing of feature correlations. Sequence visualisation, Statistical calculation Metagenomics, Sequencing To update Metagenomics metagenomeseq_normalization iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/metagenomeseq 1.16.0-0.0.1 bioconductor-metagenomeseq 1.43.0 (1/1) (0/1) (1/1) True True +metaphlan 10507.0 427.0 customize_metaphlan_database, extract_metaphlan_database, merge_metaphlan_tables, metaphlan MetaPhlAn for Metagenomic Phylogenetic Analysis metaphlan MetaPhlAn Computational tool for profiling the composition of microbial communities from metagenomic shotgun sequencing data. Nucleic acid sequence analysis, Phylogenetic tree analysis Metagenomics, Phylogenomics To update https://github.com/biobakery/MetaPhlAn Metagenomics metaphlan iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/metaphlan/ 4.0.6 metaphlan 4.1.0 (1/4) (2/4) (4/4) True True +migmap 1226.0 7.0 migmap mapper for full-length T- and B-cell repertoire sequencing MiGMAP MiGMAP Mapper for full-length T- and B-cell repertoire sequencing. Sequence analysis, Read mapping Immunoproteins, genes and antigens, Sequence analysis Up-to-date https://github.com/mikessh/migmap RNA, Sequence Analysis migmap iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/migmap 1.0.3 migmap 1.0.3 (1/1) (0/1) (1/1) True False +minia 2206.0 109.0 minia Short-read assembler based on a de Bruijn graph minia Minia Short-read assembler based on a de Bruijn graph, capable of assembling a human genome on a desktop computer in a day. Genome assembly Sequence assembly Up-to-date https://gatb.inria.fr/software/minia/ Assembly minia iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/minia 3.2.6 minia 3.2.6 (0/1) (1/1) (1/1) True True +miniasm 11938.0 178.0 miniasm Miniasm - Ultrafast de novo assembly for long noisy reads (though having no consensus step) To update https://github.com/lh3/miniasm Assembly miniasm iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/miniasm 0.3_r179 miniasm 0.3 (1/1) (1/1) (1/1) True True +miniprot 813.0 15.0 miniprot, miniprot_index Align a protein sequence against a genome with affine gap penalty, splicing and frameshift. Up-to-date https://github.com/lh3/miniprot Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/miniprot 0.12 miniprot 0.12 (0/2) (0/2) (2/2) True True +mirnature 10.0 4.0 mirnature Computational detection of canonical microRNAs Up-to-date https://github.com/Bierinformatik/miRNAture RNA, Sequence Analysis mirnature iuc https://github.com/Bierinformatik/miRNAture 1.1 mirnature 1.1 (0/1) (0/1) (1/1) True False +mitobim 881.0 66.0 mitobim assemble mitochondrial genomes Up-to-date https://github.com/chrishah/MITObim Assembly mitobim iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mitobim 1.9.1 mitobim 1.9.1 (0/1) (1/1) (1/1) True False +mitos 32022.0 58.0 mitos, mitos2 de-novo annotation of metazoan mitochondrial genomes mitos MITOS De novo metazoan mitochondrial genome annotation. Genome annotation Zoology, Whole genome sequencing To update http://mitos.bioinf.uni-leipzig.de/ Sequence Analysis mitos iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mitos 1.1.5 mitos 2.1.7 (1/2) (1/2) (2/2) True True +mlst 9304.0 635.0 mlst, mlst_list Scan contig files against PubMLST typing schemes mlst MLST Multi Locus Sequence Typing from an assembled genome or from a set of reads. Taxonomic classification Immunoproteins, genes and antigens To update https://github.com/tseemann/mlst Sequence Analysis mlst iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mlst 2.22.0 mlst 2.23.0 (2/2) (2/2) (2/2) True True +mothur mothur_align_check, mothur_align_seqs, mothur_amova, mothur_anosim, mothur_bin_seqs, mothur_biom_info, mothur_chimera_bellerophon, mothur_chimera_ccode, mothur_chimera_check, mothur_chimera_perseus, mothur_chimera_pintail, mothur_chimera_slayer, mothur_chimera_uchime, mothur_chimera_vsearch, mothur_chop_seqs, mothur_classify_otu, mothur_classify_seqs, mothur_classify_tree, mothur_clearcut, mothur_cluster_classic, mothur_cluster_fragments, mothur_cluster_split, mothur_cluster, mothur_collect_shared, mothur_collect_single, mothur_consensus_seqs, mothur_cooccurrence, mothur_corr_axes, mothur_count_groups, mothur_count_seqs, mothur_create_database, mothur_degap_seqs, mothur_deunique_seqs, mothur_deunique_tree, mothur_dist_seqs, mothur_dist_shared, mothur_fastq_info, mothur_filter_seqs, mothur_filter_shared, mothur_get_communitytype, mothur_get_coremicrobiome, mothur_get_dists, mothur_get_group, mothur_get_groups, mothur_get_label, mothur_get_lineage, mothur_get_mimarkspackage, mothur_get_otulabels, mothur_get_otulist, mothur_get_oturep, mothur_get_otus, mothur_get_rabund, mothur_get_relabund, mothur_get_sabund, mothur_get_seqs, mothur_get_sharedseqs, mothur_heatmap_bin, mothur_heatmap_sim, mothur_homova, mothur_indicator, mothur_lefse, mothur_libshuff, mothur_list_otulabels, mothur_list_seqs, mothur_make_biom, mothur_make_contigs, mothur_make_design, mothur_make_fastq, mothur_make_group, mothur_make_lefse, mothur_make_lookup, mothur_make_shared, mothur_make_sra, mothur_mantel, mothur_merge_count, mothur_merge_files, mothur_merge_groups, mothur_merge_sfffiles, mothur_merge_taxsummary, mothur_metastats, mothur_mimarks_attributes, mothur_nmds, mothur_normalize_shared, mothur_otu_association, mothur_otu_hierarchy, mothur_pairwise_seqs, mothur_parse_list, mothur_parsimony, mothur_pca, mothur_pcoa, mothur_pcr_seqs, mothur_phylo_diversity, mothur_phylotype, mothur_pre_cluster, mothur_primer_design, mothur_rarefaction_shared, mothur_rarefaction_single, mothur_remove_dists, mothur_remove_groups, mothur_remove_lineage, mothur_remove_otulabels, mothur_remove_otus, mothur_remove_rare, mothur_remove_seqs, mothur_rename_seqs, mothur_reverse_seqs, mothur_screen_seqs, mothur_sens_spec, mothur_seq_error, mothur_sffinfo, mothur_shhh_flows, mothur_shhh_seqs, mothur_sort_seqs, mothur_split_abund, mothur_split_groups, mothur_sub_sample, mothur_summary_qual, mothur_summary_seqs, mothur_summary_shared, mothur_summary_single, mothur_summary_tax, mothur_taxonomy_to_krona, mothur_tree_shared, mothur_trim_flows, mothur_trim_seqs, mothur_unifrac_unweighted, mothur_unifrac_weighted, mothur_unique_seqs, mothur_venn Mothur wrappers mothur mothur Open-source, platform-independent, community-supported software for describing and comparing microbial communities DNA barcoding, Sequencing quality control, Sequence clustering, Taxonomic classification, Visualisation, Sequence read processing, Phylogenetic analysis Microbial ecology, Taxonomy, Sequence analysis, Phylogeny To update https://www.mothur.org Metagenomics mothur iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mothur 1.0 mothur 1.48.0 (129/129) (129/129) (129/129) True True +multigsea 53.0 2.0 multigsea GSEA-based pathway enrichment analysis for multi-omics data multiGSEA multiGSEA A GSEA-based pathway enrichment analysis for multi-omics data.multiGSEA: a GSEA-based pathway enrichment analysis for multi-omics data, BMC Bioinformatics 21, 561 (2020).Combining GSEA-based pathway enrichment with multi omics data integration. Gene-set enrichment analysis, Aggregation, Pathway analysis Metabolomics, Molecular interactions, pathways and networks, Proteomics, Transcriptomics, Small molecules Up-to-date https://bioconductor.org/packages/devel/bioc/html/multiGSEA.html Transcriptomics, Proteomics, Statistics multigsea iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/multigsea 1.12.0 bioconductor-multigsea 1.12.0 (0/1) (0/1) (1/1) True True +multiqc 162790.0 8320.0 multiqc MultiQC aggregates results from bioinformatics analyses across many samples into a single report multiqc MultiQC MultiQC aggregates results from multiple bioinformatics analyses across many samples into a single report. It searches a given directory for analysis logs and compiles a HTML report. It's a general use tool, perfect for summarising the output from numerous bioinformatics tools. Validation Sequencing, Bioinformatics To update http://multiqc.info/ Fastq Manipulation, Statistics, Visualization multiqc iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/multiqc 1.11 multiqc 1.20 (1/1) (1/1) (1/1) True True +mummer4 mummer_delta_filter, mummer_dnadiff, mummer_mummer, mummer_mummerplot, mummer_nucmer, mummer_show_coords Mummer4 Tools mumer4 MUMmer4 System for rapidly aligning large DNA sequences to one another. Multiple sequence alignment Sequence analysis, Human genetics Up-to-date https://github.com/mummer4/mummer Sequence Analysis mummer4 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mummer4 4.0.0rc1 mummer4 4.0.0rc1 (6/6) (6/6) (6/6) True False +mykrobe mykrobe_predict Antibiotic resistance predictions Mykrobe Mykrobe Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.Antibiotic resistance prediction in minutes.Table of Contents generated with DocToc.AMR prediction (Mykrobe predictor).Before attempting to install with bioconda, please ensure you have your channels set up as specified in the documentation. If you don't, you may run into issues with an older version of mykrobe being installed Antimicrobial resistance prediction, Variant calling, Genotyping, Sequence trimming Whole genome sequencing, Genotype and phenotype, Probes and primers, Genetic variation, Metagenomics To update https://github.com/Mykrobe-tools/mykrobe Sequence Analysis mykrobe iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/mykrobe 0.10.0 mykrobe 0.13.0 (0/1) (0/1) (0/1) True True +naltorfs bicodon_counts_from_fasta, codon_freq_from_bicodons, find_nested_alt_orfs nAlt-ORFs: Nested Alternate Open Reading Frames (nAltORFs) Up-to-date https://github.com/BlankenbergLab/nAltORFs Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/naltorfs/ 0.1.2 naltorfs 0.1.2 (3/3) (0/3) (0/3) True False +nanocompore nanocompore_db, nanocompore_sampcomp Nanocompore compares 2 ONT nanopore direct RNA sequencing datasets from different experimental conditions expected to have a significant impact on RNA modifications. It is recommended to have at least 2 replicates per condition. For example one can use a control condition with a significantly reduced number of modifications such as a cell line for which a modification writing enzyme was knocked-down or knocked-out. Alternatively, on a smaller scale transcripts of interests could be synthesized in-vitro. Nanocompore Nanocompore RNA modifications detection by comparative Nanopore direct RNA sequencing.RNA modifications detection from Nanopore dRNA-Seq data.Nanocompore identifies differences in ONT nanopore sequencing raw signal corresponding to RNA modifications by comparing 2 samples.Analyses performed for the nanocompore paper.Nanocompore compares 2 ONT nanopore direct RNA sequencing datasets from different experimental conditions expected to have a significant impact on RNA modifications. It is recommended to have at least 2 replicates per condition. For example one can use a control condition with a significantly reduced number of modifications such as a cell line for which a modification writing enzyme was knocked-down or knocked-out. Alternatively, on a smaller scale transcripts of interests could be synthesized in-vitro Post-translation modification site prediction, PolyA signal detection, Genotyping, k-mer counting Functional, regulatory and non-coding RNA, RNA-Seq, Gene transcripts, Transcriptomics, Transcription factors and regulatory sites To update https://nanocompore.rna.rocks/ Sequence Analysis nanocompore iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nanocompore 1.0.0rc3.post2 nanocompore 1.0.4 (0/2) (1/2) (2/2) True True +nanoplot 63235.0 2195.0 nanoplot Plotting tool for long read sequencing data and alignments To update https://github.com/wdecoster/NanoPlot Visualization nanoplot iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nanoplot/ 1.41.0 nanoplot 1.42.0 (1/1) (1/1) (1/1) True True +nanopolishcomp nanopolishcomp_eventaligncollapse, nanopolishcomp_freqmethcalculate NanopolishComp contains 2 modules. Eventalign_collapse collapses the raw file generated by nanopolish eventalign by kmers rather than by event. Freq_meth_calculate methylation frequency at genomic CpG sites from the output of nanopolish call-methylation. To update https://a-slide.github.io/NanopolishComp Sequence Analysis nanopolishcomp iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nanopolishcomp 0.6.11 nanopolishcomp 0.6.12 (0/2) (0/2) (2/2) True True +ncbi_fcs_gx ncbi_fcs_gx FCS-GX detects contamination from foreign organisms in genome sequences using the genome cross-species aligner (GX). Up-to-date https://github.com/ncbi/fcs-gx Sequence Analysis ncbi_fcs_gx iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/ncbi_fcs_gx 0.5.0 ncbi-fcs-gx 0.5.0 (1/1) (0/1) (0/1) False +necat 667.0 95.0 necat Error correction and de-novo assembly for ONT Nanopore reads necat NECAT NECAT is an error correction and de-novo assembly tool for Nanopore long noisy reads. De-novo assembly Sequence assembly Up-to-date https://github.com/xiaochuanle/NECAT Assembly necat iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/necat 0.0.1_update20200803 necat 0.0.1_update20200803 (0/1) (0/1) (1/1) True False +newick_utils 25505.0 448.0 newick_display Perform operations on Newick trees newick_utilities Newick Utilities The Newick Utilities are a set of command-line tools for processing phylogenetic trees. They can process arbitrarily large amounts of data and do not require user interaction, which makes them suitable for automating phylogeny processing tasks. Phylogenetic tree generation, Phylogenetic tree analysis, Phylogenetic tree reconstruction Phylogeny, Genomics, Computer science To update http://cegg.unige.ch/newick_utils Visualization, Metagenomics newick_utils iuc https://github.com/tjunier/newick_utils 1.6+galaxy1 newick_utils 1.6 (1/1) (1/1) (1/1) True True +nextclade 3527.0 169.0 nextalign, nextclade Identify differences between your sequences and a reference sequence used by Nextstrain To update https://github.com/nextstrain/nextclade Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nextclade 2.7.0 nextalign 2.14.0 (1/2) (1/2) (2/2) True True +nonpareil 142.0 5.0 nonpareil Estimate average coverage in metagenomic datasets To update http://nonpareil.readthedocs.io Metagenomics nonpareil iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nonpareil 3.1.1 nonpareil 3.4.1 (1/1) (0/1) (1/1) True True +novoplasty 6384.0 162.0 novoplasty NOVOPlasty is a de novo assembler and heteroplasmy/variance caller for short circular genomes. To update https://github.com/ndierckx/NOVOPlasty Assembly novoplasty iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/novoplasty 4.3.1 novoplasty 4.3.5 (0/1) (1/1) (1/1) True False +nugen_nudup nugen_nudup Marks/removes PCR introduced duplicate molecules based on the molecular tagging technology used in NuGEN products. Up-to-date http://nugentechnologies.github.io/nudup/ SAM, Metagenomics, Sequence Analysis, Transcriptomics nugen_nudup iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/nugen_nudup 2.3.3 nudup 2.3.3 (0/1) (0/1) (0/1) True True +obitools obi_illumina_pairend, obi_ngsfilter, obi_annotate, obi_clean, obi_convert, obi_grep, obi_sort, obi_stat, obi_tab, obi_uniq OBITools is a set of programs developed to simplify the manipulation of sequence files obitools OBITools Set of python programs developed to simplify the manipulation of sequence files. They were mainly designed to help us for analyzing Next Generation Sequencer outputs (454 or Illumina) in the context of DNA Metabarcoding. Sequence analysis, Sequence analysis Sequence analysis, DNA, Sequencing Up-to-date http://metabarcoding.org/obitools Sequence Analysis obitools iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/obitools 1.2.13 obitools 1.2.13 (0/10) (10/10) (10/10) True False +odgi odgi_build, odgi_viz Representing large genomic variation graphs with minimal memory overhead requires a careful encoding of the graph entities. odgi follows the dynamic GBWT in developing a byte-packed version of the graph and paths through it. To update https://github.com/vgteam/odgi Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/odgi/ 0.3 odgi 0.8.4 (0/2) (0/2) (2/2) True False +omark omark Proteome quality assessment software To update https://github.com/DessimozLab/OMArk Sequence Analysis omark iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/omark/ 0.3.0 (0/1) (0/1) (0/1) False +ont_fast5_api ont_fast5_api_compress_fast5, ont_fast5_api_fast5_subset, ont_fast5_api_multi_to_single_fast5, ont_fast5_api_single_to_multi_fast5 ont_fast5_api is a simple interface to HDF5 files of the Oxford Nanopore FAST5 file format. To update https://github.com/nanoporetech/ont_fast5_api/ Nanopore ont_fast5_api iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ont_fast5_api 3.1.3 ont-fast5-api 4.1.2 (0/4) (0/4) (4/4) True False +optitype 321.0 24.0 optitype Precision HLA typing from NGS data Up-to-date https://github.com/FRED-2/OptiType Sequence Analysis optitype iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/optitype1 1.3.5 optitype 1.3.5 (0/1) (0/1) (1/1) True False +orfipy 774.0 53.0 orfipy Galaxy wrapper for ORFIPY orfipy orfipy A fast and flexible tool for extracting ORFs.orfipy is a tool written in python/cython to extract ORFs in extremely an fast and flexible manner. Other popular ORF searching tools are OrfM and getorf. Compared to OrfM and getorf, orfipy provides the most options to fine tune ORF searches. orfipy uses multiple CPU cores and is particularly faster for data containing multiple smaller fasta sequences such as de-novo transcriptome assemblies. Please read the preprint here. Coding region prediction, Database search, Transcriptome assembly, De-novo assembly Computer science, RNA-Seq, Transcriptomics, Small molecules Up-to-date https://github.com/urmi-21/orfipy Sequence Analysis orfipy iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/orfipy 0.0.4 orfipy 0.0.4 (1/1) (0/1) (1/1) True True +orthofinder orthofinder_onlygroups Accurate inference of orthologous gene groups made easy OrthoFinder OrthoFinder OrthoFinder is a fast, accurate and comprehensive platform for comparative genomics. It finds orthogroups and orthologs, infers rooted gene trees for all orthogroups and identifies all of the gene duplcation events in those gene trees. It also infers a rooted species tree for the species being analysed and maps the gene duplication events from the gene trees to branches in the species tree. OrthoFinder also provides comprehensive statistics for comparative genomic analyses. Genome comparison, Phylogenetic tree generation (from molecular sequences), Phylogenetic tree analysis, Genome alignment Phylogenetics, Phylogenomics, Bioinformatics, Comparative genomics, Sequence analysis Up-to-date https://github.com/davidemms/OrthoFinder Phylogenetics, Sequence Analysis orthofinder iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/orthofinder 2.5.5 orthofinder 2.5.5 (0/1) (1/1) (1/1) True True +pangolin 7276.0 259.0 pangolin Pangolin assigns SARS-CoV-2 genome sequences their most likely lineages under the Pango nomenclature system. Up-to-date https://github.com/cov-lineages/pangolin Sequence Analysis pangolin iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pangolin 4.3 pangolin 4.3 (1/1) (1/1) (1/1) True False +parse_mito_blast 90.0 31.0 parse_mito_blast Filtering blast out from querying assembly against mitochondrial database. Up-to-date https://raw.githubusercontent.com/VGP/vgp-assembly/master/galaxy_tools/parse_mito_blast/parse_mito_blast.py Sequence Analysis parse_mito_blast iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/parse_mito_blast 1.0.2 parse_mito_blast 1.0.2 (1/1) (1/1) (1/1) True False +pathview 5260.0 565.0 pathview Pathview is a tool set for pathway based data integration and visualization. pathview pathview Tool set for pathway based data integration and visualization that maps and renders a wide variety of biological data on relevant pathway graphs. It downloads the pathway graph data, parses the data file, maps user data to the pathway, and render pathway graph with the mapped data. In addition, it integrates with pathway and gene set (enrichment) analysis tools for large-scale and fully automated analysis. Pathway or network analysis, Pathway or network visualisation Molecular interactions, pathways and networks, Systems biology, Data visualisation To update https://bioconductor.org/packages/release/bioc/html/pathview.html Statistics, RNA, Micro-array Analysis pathview iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pathview 1.34.0 bioconductor-pathview 1.42.0 (1/1) (1/1) (1/1) True False pharokka 2565.0 74.0 pharokka rapid standardised annotation tool for bacteriophage genomes and metagenomes " pharokka " To update https://github.com/gbouras13/pharokka Genome annotation pharokka iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/pharokka 1.3.2 " pharokka " (0/1) (1/1) (1/1) True True -phyloseq phyloseq_from_dada2, phyloseq_plot_ordination, phyloseq_plot_richness Handling and analysis of high-throughput microbiome census data phyloseq phyloseq Provides a set of classes and tools to facilitate the import, storage, analysis, and graphical display of microbiome census data. Deposition, Analysis, Visualisation Microbiology, Sequence analysis, Metagenomics To update https://www.bioconductor.org/packages/release/bioc/html/phyloseq.html Metagenomics phyloseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/phyloseq 1.38.0 bioconductor-phyloseq 1.46.0 (0/3) (0/3) (3/3) True True -phyml 1770.0 104.0 phyml PhyML is a phylogeny software based on the maximum-likelihood principle. phyml PhyML Phylogenetic estimation software using Maximum Likelihood Phylogenetic tree generation (maximum likelihood and Bayesian methods) Phylogenetics, Bioinformatics, Phylogenetics Up-to-date http://www.atgc-montpellier.fr/phyml/ Phylogenetics phyml iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/phyml 3.3.20220408 phyml 3.3.20220408 (0/1) (1/1) (1/1) True True -picrust picrust_categorize, picrust_compare_biom, picrust_format_tree_and_trait_table, picrust_metagenome_contributions, picrust_normalize_by_copy_number, picrust_predict_metagenomes PICRUSt wrappers picrust PICRUSt PICRUSt (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) is a bioinformatics software package designed to predict metagenome functional content from marker gene (e.g., 16S rRNA) surveys and full genomes. Phylogenetic reconstruction, Expression analysis, Genome annotation, DNA barcoding Metagenomics, Microbial ecology, Functional, regulatory and non-coding RNA, Metagenomic sequencing To update https://picrust.github.io/picrust/ Metagenomics picrust iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/picrust 1.1.1 picrust 1.1.4 (0/6) (6/6) (5/6) True True -picrust2 picrust2_add_descriptions, picrust2_hsp, picrust2_metagenome_pipeline, picrust2_pathway_pipeline, picrust2_pipeline, picrust2_place_seqs, picrust2_shuffle_predictions PICRUSt2: Phylogenetic Investigation of Communities by Reconstruction of Unobserved States picrust2 PICRUSt2 PICRUSt2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) is a software for predicting functional abundances based only on marker gene sequences. Phylogenetic reconstruction, Expression analysis, Rarefaction, Pathway analysis Metagenomics, Microbiology, Phylogenetics, Metagenomic sequencing To update https://github.com/picrust/picrust2/wiki Metagenomics picrust2 iuc https://github.com/picrust/picrust2 2.5.1 picrust2 2.5.2 (0/7) (7/7) (7/7) True True -plasflow 22589.0 278.0 PlasFlow PlasFlow - Prediction of plasmid sequences in metagenomic contigs. Up-to-date https://github.com/smaegol/PlasFlow Sequence Analysis plasflow iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/plasflow 1.1.0 plasflow 1.1.0 (1/1) (1/1) (1/1) True True -plasmidfinder 22.0 8.0 plasmidfinder """PlasmidFinder provides the detection of replicons in the WGSand assigns the plasmids under study to lineages that trace backthe information to the existing knowledge on Inc groups and suggestspossible reference plasmids for each lineage""" PlasmidFinder PlasmidFinder PlasmidFinder is a tool for the identification and typing of Plasmid Replicons in Whole-Genome Sequencing (WGS). Genome assembly, Scaffolding, Multilocus sequence typing Whole genome sequencing, Sequence assembly, Mapping, Probes and primers Up-to-date https://bitbucket.org/genomicepidemiology/plasmidfinder/src/master/ Sequence Analysis plasmidfinder iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/plasmidfinder 2.1.6 plasmidfinder 2.1.6 (0/1) (0/1) (1/1) True True -polypolish 239.0 24.0 polypolish """Polypolish is a tool for polishing genome assemblies with short reads.Polypolish uses SAM files where each read has been aligned to all possible locations (not just a single best location).This allows it to repair errors in repeat regions that other alignment-based polishers cannot fix.""" Polypolish Polypolish Polypolish is a tool for polishing genome assemblies with short reads. Unlike other tools in this category, Polypolish uses SAM files where each read has been aligned to all possible locations (not just a single best location). This allows it to repair errors in repeat regions that other alignment-based polishers cannot fix. Genome assembly, Read mapping, Mapping assembly, Sequencing error detection Sequence assembly, Sequence composition, complexity and repeats, Mapping To update https://github.com/rrwick/Polypolish Sequence Analysis polypolish iuc https://github.com/mesocentre-clermont-auvergne/galaxy-tools/tree/master/tools/polypolish 0.5.0 polypolish 0.6.0 (0/1) (0/1) (1/1) True False -presto presto_alignsets, presto_assemblepairs, presto_buildconsensus, presto_collapseseq, presto_filterseq, presto_maskprimers, presto_pairseq, presto_parseheaders, presto_parselog, presto_partition, prestor_abseq3 pRESTO toolkit for immune repertoire analysis. presto pRESTO Integrated collection of platform-independent Python modules for processing raw reads from high-throughput (next-generation) sequencing of lymphocyte repertoires. Nucleic acid sequence analysis Sequencing, DNA, Immunology To update https://presto.readthedocs.io/ Sequence Analysis presto iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/presto 0.6.2 presto 0.7.2 (11/11) (0/11) (0/11) True False -pretext pretext_graph, pretext_map, pretext_snapshot Process genome contacts maps processing images. Up-to-date https://github.com/wtsi-hpag/PretextSnapshot Sequence Analysis suite_pretext iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pretext 0.0.6 pretextgraph 0.0.6 (2/3) (2/3) (3/3) True False -prinseq 7881.0 70.0 prinseq PRINSEQ is a tool for easy and rapid quality control and data processing of metagenomic and metatranscriptomic datasets prinseq PRINSEQ PRINSEQ is a sequence processing tool that can be used to filter, reformat and trim genomic and metagenomic sequence data. It generates summary statistics of the input in graphical and tabular formats that can be used for quality control steps. PRINSEQ is available as both standalone and web-based versions. Read pre-processing, Sequence trimming, Sequence contamination filtering Transcriptomics, Metagenomics, Genomics To update http://prinseq.sourceforge.net/manual.html Fastq Manipulation, Metagenomics prinseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/prinseq/ @TOOL_VERSION+galaxy2 prinseq 0.20.4 (1/1) (0/1) (1/1) True False -progressivemauve 1734.0 286.0 progressivemauve, xmfa2gff3 Mauve/ProgressiveMauve Multiple Sequence Aligner To update Sequence Analysis progressivemauve iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/progressivemauve progressivemauve snapshot_2015_02_13 (2/2) (0/2) (2/2) True False -prokka 371445.0 3233.0 prokka Rapid annotation of prokaryotic genomes prokka Prokka Software tool to annotate bacterial, archaeal and viral genomes quickly and produce standards-compliant output files. Gene prediction, Coding region prediction, Genome annotation Genomics, Model organisms, Virology Up-to-date http://github.com/tseemann/prokka Sequence Analysis prokka crs4 https://github.com/galaxyproject/tools-iuc/tree/master/tools/prokka/ 1.14.6 prokka 1.14.6 (1/1) (1/1) (1/1) True True -prot-scriber prot_scriber Protein annotation of short human readable descriptions To update https://github.com/usadellab/prot-scriber Proteomics prot_scriber iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/prot-scriber 0.1.4 prot-scriber 0.1.5 (0/1) (0/1) (1/1) True False -proteinortho 2092.0 125.0 proteinortho, proteinortho_grab_proteins, proteinortho_summary Proteinortho is a tool to detect orthologous proteins/genes within different species. proteinortho Proteinortho Proteinortho is a tool to detect orthologous genes within different species Homology-based gene prediction Phylogeny Up-to-date https://gitlab.com/paulklemm_PHD/proteinortho Proteomics proteinortho iuc https://gitlab.com/paulklemm_PHD/proteinortho 6.3.1 proteinortho 6.3.1 (0/3) (0/3) (3/3) True True -pureclip 1423.0 36.0 pureclip PureCLIP is an HMM based peak caller specifically designed for eCLIP/iCLIP data To update https://github.com/skrakau/PureCLIP Sequence Analysis, RNA, CLIP-seq pureclip iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pureclip 1.0.4 pureclip 1.3.1 (0/1) (0/1) (1/1) True False -purge_dups 16800.0 167.0 purge_dups Purge haplotigs and overlaps in an assembly based on read depth purge_dups purge_dups Identifying and removing haplotypic duplication in primary genome assemblies | haplotypic duplication identification tool | scripts/pd_config.py: script to generate a configuration file used by run_purge_dups.py | purge haplotigs and overlaps in an assembly based on read depth | Given a primary assembly pri_asm and an alternative assembly hap_asm (optional, if you have one), follow the steps shown below to build your own purge_dups pipeline, steps with same number can be run simultaneously. Among all the steps, although step 4 is optional, we highly recommend our users to do so, because assemblers may produce overrepresented seqeuences. In such a case, The final step 4 can be applied to remove those seqeuences Genome assembly, Read binning, Scaffolding Sequence assembly Up-to-date https://github.com/dfguan/purge_dups Assembly purge_dups iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/purge_dups 1.2.6 purge_dups 1.2.6 (1/1) (1/1) (1/1) True False -pycoqc 21123.0 350.0 pycoqc QC metrics for ONT Basecalling Up-to-date https://github.com/tleonardi/pycoQC Nanopore pycoqc iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pycoqc 2.5.2 pycoqc 2.5.2 (1/1) (1/1) (1/1) True True -pygenometracks 11332.0 377.0 pygenomeTracks pyGenomeTracks: Standalone program and library to plot beautiful genome browser tracks. Up-to-date https://github.com/deeptools/pyGenomeTracks Visualization pygenometracks iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pygenometracks 3.8 pygenometracks 3.8 (1/1) (1/1) (1/1) True True -pysradb pysradb_search pysradb allows to retrieve metadata, such as run accession numbers, from SRA and ENA based on multiple criteria. pysradb pysradb Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive. Deposition, Data retrieval Sequencing, Gene transcripts, Bioinformatics To update https://github.com/saketkc/pysradb Sequence Analysis pysradb_search iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pysradb 1.4.2 pysradb 2.2.0 (0/1) (0/1) (1/1) True False -qiime_add_on qiime_collapse_samples, qiime_make_otu_table QIIME to perform microbial community analysis To update http://www.qiime.org Metagenomics qiime iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/qiime/ qiime 1.9.1 (0/2) (0/2) (2/2) True True -qiime_core qiime_align_seqs, qiime_alpha_diversity, qiime_alpha_rarefaction, qiime_assign_taxonomy, qiime_beta_diversity, qiime_beta_diversity_through_plots, qiime_compare_categories, qiime_core_diversity, qiime_count_seqs, qiime_extract_barcodes, qiime_filter_alignment, qiime_filter_fasta, qiime_filter_otus_from_otu_table, qiime_filter_samples_from_otu_table, qiime_filter_taxa_from_otu_table, qiime_jackknifed_beta_diversity, qiime_make_emperor, qiime_make_otu_heatmap, qiime_make_phylogeny, qiime_multiple_join_paired_ends, qiime_multiple_split_libraries_fastq, qiime_pick_closed_reference_otus, qiime_pick_open_reference_otus, qiime_pick_otus, qiime_pick_rep_set, qiime_plot_taxa_summary, qiime_split_libraries, qiime_split_libraries_fastq, qiime_summarize_taxa, qiime_summarize_taxa_through_plots, qiime_upgma_cluster, qiime_validate_mapping_file QIIME to perform microbial community analysis To update http://www.qiime.org Metagenomics qiime iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/qiime/ qiime 1.9.1 (0/32) (0/32) (32/32) True True -qq_tools qq_manhattan To update https://CRAN.R-project.org/package=qqman Visualization, Variant Analysis iuc 0.1.0 r-qqman 0.1.4 (0/1) (0/1) (0/1) True False -qualimap qualimap_bamqc, qualimap_counts, qualimap_multi_bamqc, qualimap_rnaseq qualimap QualiMap Platform-independent application written in Java and R that provides both a Graphical User Inteface (GUI) and a command-line interface to facilitate the quality control of alignment sequencing data. Sequencing quality control Data quality management To update http://qualimap.bioinfo.cipf.es/ Sequence Analysis, Transcriptomics, SAM qualimap iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/qualimap 2.2.2d qualimap 2.3 (4/4) (4/4) (4/4) True True -quast 51567.0 3567.0 quast Quast (Quality ASsessment Tool) evaluates genome assemblies. quast QUAST QUAST stands for QUality ASsessment Tool. It evaluates a quality of genome assemblies by computing various metrics and providing nice reports. Visualisation, Sequence assembly validation Sequence assembly Up-to-date http://quast.bioinf.spbau.ru/ Assembly quast iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/quast 5.2.0 quast 5.2.0 (1/1) (1/1) (1/1) True True -quickmerge quickmerge Merge long-read and hybrid assemblies to increase contiguity quickmerge quickmerge Quickmerge is a program that uses complementary information from genomes assembled with long reads in order to improve contiguity, and works with assemblies derived from both Pacific Biosciences or Oxford Nanopore. Quickmerge will even work with hybrid assemblies made by combining long reads and Illumina short reads. Genome assembly, Scaffolding, De-novo assembly, Genotyping Structural variation, Sequence assembly, DNA polymorphism, Whole genome sequencing, Genotype and phenotype Up-to-date https://github.com/mahulchak/quickmerge Assembly quickmerge galaxy-australia https://github.com/galaxyproject/tools-iuc/tree/master/tools/quickmerge 0.3 quickmerge 0.3 (0/1) (0/1) (0/1) True True -ragtag 2833.0 237.0 ragtag Reference-guided scaffolding of draft genomes tool. ragtag ragtag RagTag is a collection of software tools for scaffolding and improving modern genome assemblies. Genome assembly Sequence assembly Up-to-date https://github.com/malonge/RagTag Assembly ragtag iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ragtag 2.1.0 ragtag 2.1.0 (0/1) (0/1) (1/1) True False -rapidnj 176.0 14.0 rapidnj Galaxy wrapper for the RapidNJ tool rapidnj RapidNJ A tool for fast canonical neighbor-joining tree construction. Phylogenetic tree generation Phylogeny Up-to-date https://birc.au.dk/software/rapidnj/ Phylogenetics rapidnj iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/rapidnj 2.3.2 rapidnj 2.3.2 (1/1) (0/1) (1/1) True False -rasusa rasusa Randomly subsample sequencing reads to a specified coverage rasusa rasusa Produces an unbiased subsample of your reads Up-to-date https://github.com/mbhall88/rasusa Sequence Analysis rasusa iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/rasusa 0.8.0 rasusa 0.8.0 (0/1) (0/1) (0/1) False -raven 6902.0 262.0 raven Raven is a de novo genome assembler for long uncorrected reads. To update https://github.com/lbcb-sci/raven Assembly iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/raven 1.8.0 raven-assembler 1.8.3 (0/1) (1/1) (1/1) True False -raxml 6808.0 383.0 raxml RAxML - A Maximum Likelihood based phylogenetic inference raxml RAxML A tool for Phylogenetic Analysis and Post-Analysis of Large Phylogenies. Sequence analysis, Phylogenetic tree analysis Phylogenetics, Sequence analysis To update http://www.exelixis-lab.org/web/software/raxml/ Phylogenetics raxml iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/raxml 8.2.12 raxml 8.2.13 (1/1) (1/1) (1/1) True True -read_it_and_keep 3370.0 71.0 read_it_and_keep Rapid decontamination of SARS-CoV-2 sequencing reads To update https://github.com/GenomePathogenAnalysisService/read-it-and-keep Sequence Analysis read_it_and_keep iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/read-it-and-keep 0.2.2 read-it-and-keep 0.3.0 (1/1) (0/1) (1/1) True True -recentrifuge 331.0 48.0 recentrifuge """With Recentrifuge, researchers can analyze results from taxonomic classifiers using interactive charts with emphasis on the confidence level of the classifications.In addition to contamination-subtracted samples.Recentrifuge provides shared and exclusive taxa per sample,thus enabling robust contamination removal and comparative analysis in environmental and clinical metagenomics.""" Recentrifuge Recentrifuge Robust comparative analysis and contamination removal for metagenomics. Taxonomic classification, Expression analysis, Cross-assembly Metagenomics, Microbial ecology, Metagenomic sequencing Up-to-date https://github.com/khyox/recentrifuge Metagenomics recentrifuge iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/recentrifuge 1.14.0 recentrifuge 1.14.0 (0/1) (0/1) (1/1) True True -red 578.0 88.0 red Red (REpeat Detector) Up-to-date https://github.com/BioinformaticsToolsmith/Red Sequence Analysis red iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/red 2018.09.10 red 2018.09.10 (1/1) (1/1) (1/1) True False -repeatmasker repeatmasker_wrapper RepeatMasker is a program that screens DNA sequences for interspersed repeats and low complexity DNA sequences. repeatmasker RepeatMasker A program that screens DNA sequences for interspersed repeats and low complexity DNA sequences. The output of the program is a detailed annotation of the repeats that are present in the query sequence as well as a modified version of the query sequence in which all the annotated repeats have been masked (default: replaced by Ns). Genome annotation Sequence analysis, Sequence composition, complexity and repeats Up-to-date http://www.repeatmasker.org/ Sequence Analysis repeat_masker bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/repeatmasker 4.1.5 repeatmasker 4.1.5 (1/1) (1/1) (1/1) True False -repeatmodeler 1177.0 217.0 repeatmodeler RepeatModeler - Model repetitive DNA To update https://www.repeatmasker.org/RepeatModeler/ Genome annotation repeatmodeler csbl https://github.com/galaxyproject/tools-iuc/tree/master/tools/repeatmodeler 2.0.5 (1/1) (1/1) (1/1) True False -ribowaltz ribowaltz_process, ribowaltz_plot Calculation of optimal P-site offsets, diagnostic analysis and visual inspection of ribosome profiling data riboWaltz riboWaltz riboWaltz is an R package for calculation of optimal P-site offsets, diagnostic analysis and visual inspection of ribosome profiling data. Computational biology To update https://github.com/LabTranslationalArchitectomics/riboWaltz Transcriptomics, RNA iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ribowaltz 1.2.0 ribowaltz 2.0 (0/2) (0/2) (2/2) True False -rnaquast 1110.0 109.0 rna_quast rnaQuast (RNA Quality Assessment Tool) evaluates genome assemblies. rnaQUAST rnaQUAST Quality assessment tool for de novo transcriptome assemblies. De-novo assembly, Transcriptome assembly, Sequence assembly validation Sequence assembly, Transcriptomics, RNA-seq Up-to-date https://github.com/ablab/rnaquast Assembly, RNA rnaquast iuc https://git.ufz.de/lehmanju/rnaquast 2.2.3 rnaquast 2.2.3 (1/1) (0/1) (1/1) True False -roary 12225.0 656.0 roary Roary the pangenome pipeline roary Roary A high speed stand alone pan genome pipeline, which takes annotated assemblies in GFF3 format (produced by Prokka (Seemann, 2014)) and calculates the pan genome. Genome assembly DNA, Genomics, Mapping Up-to-date https://sanger-pathogens.github.io/Roary/ Sequence Analysis roary iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/roary 3.13.0 roary 3.13.0 (1/1) (1/1) (1/1) True True -rseqc 135036.0 3269.0 rseqc_FPKM_count, rseqc_RNA_fragment_size, rseqc_RPKM_saturation, rseqc_bam2wig, rseqc_bam_stat, rseqc_clipping_profile, rseqc_deletion_profile, rseqc_geneBody_coverage, rseqc_geneBody_coverage2, rseqc_infer_experiment, rseqc_inner_distance, rseqc_insertion_profile, rseqc_junction_annotation, rseqc_junction_saturation, rseqc_mismatch_profile, rseqc_read_GC, rseqc_read_NVC, rseqc_read_distribution, rseqc_read_duplication, rseqc_read_hexamer, rseqc_read_quality, rseqc_tin an RNA-seq quality control package rseqc RSeQC Provides a number of useful modules that can comprehensively evaluate high throughput sequence data especially RNA-seq data. Some basic modules quickly inspect sequence quality, nucleotide composition bias, PCR bias and GC bias, while RNA-seq specific modules evaluate sequencing saturation, mapped reads distribution, coverage uniformity, strand specificity, transcript level RNA integrity etc. Data handling Sequencing To update https://code.google.com/p/rseqc/ Convert Formats, Sequence Analysis, RNA, Transcriptomics, Visualization rseqc nilesh https://github.com/galaxyproject/tools-iuc/tree/master/tools/rseqc 5.0.1 rseqc 5.0.3 (22/22) (22/22) (22/22) True True -ruvseq 1236.0 76.0 ruvseq Remove Unwanted Variation from RNA-Seq Data ruvseq RUVSeq This package implements the remove unwanted variation (RUV) methods for the normalization of RNA-Seq read counts between samples. Differential gene expression analysis Gene expression, RNA-seq To update https://www.bioconductor.org/packages/release/bioc/html/DESeq2.html Transcriptomics, RNA, Statistics ruvseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ruvseq 1.26.0 bioconductor-ruvseq 1.36.0 (1/1) (0/1) (1/1) True False -salsa2 salsa A tool to scaffold long read assemblies with Hi-C SALSA SALSA > VERY_LOW CONFIDENCE! | > CORRECT NAME OF TOOL COULD ALSO BE 'chromosome-scale', 'reference-quality', 'Hi-C', 'scaffolder' | Integrating Hi-C links with assembly graphs for chromosome-scale assembly | SALSA: A tool to scaffold long read assemblies with Hi-C data | SALSA: A tool to scaffold long read assemblies with Hi-C | This code is used to scaffold your assemblies using Hi-C data. This version implements some improvements in the original SALSA algorithm. If you want to use the old version, it can be found in the old_salsa branch Genome assembly, De-novo assembly, Scaffolding Sequence assembly, DNA binding sites, Mapping Up-to-date https://github.com/marbl/SALSA Assembly salsa iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/salsa2 2.3 salsa2 2.3 (1/1) (1/1) (1/1) True False -sarscov2formatter 173.0 7.0 sarscov2formatter sarscov2formatter custom script Up-to-date https://github.com/nickeener/sarscov2formatter Sequence Analysis sarscov2formatter iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sarscov2formatter 1.0 sarscov2formatter 1.0 (1/1) (0/1) (1/1) True True -sarscov2summary 140.0 1.0 sarscov2summary sarscov2summary custom script To update https://github.com/nickeener/sarscov2summary Sequence Analysis sarscov2summary iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sarscov2summary 0.1 sarscov2summary 0.5 (1/1) (0/1) (1/1) True True -scanpy scanpy_cluster_reduce_dimension, scanpy_filter, scanpy_inspect, scanpy_normalize, scanpy_plot, scanpy_remove_confounders Scanpy – Single-Cell Analysis in Python scanpy SCANPY Scalable toolkit for analyzing single-cell gene expression data. It includes preprocessing, visualization, clustering, pseudotime and trajectory inference and differential expression testing. The Python-based implementation efficiently deals with datasets of more than one million cells. Differential gene expression analysis Gene expression, Cell biology, Genetics To update https://scanpy.readthedocs.io Transcriptomics, Sequence Analysis scanpy iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scanpy/ 1.9.6 scanpy 1.7.2 (6/6) (6/6) (6/6) True False -scater scater_create_qcmetric_ready_sce, scater_filter, scater_plot_dist_scatter, scater_plot_pca, scater_plot_tsne Scater (Single-Cell Analysis Toolkit for gene Expression data in R) is acollection of tools for doing various analyses of single-cell RNA-seq geneexpression data, with a focus on quality control and visualization. scater scater Pre-processing, quality control, normalization and visualization of single-cell RNA-seq data. Read pre-processing, Sequencing quality control, Sequence visualisation RNA-seq, Quality affairs, Molecular genetics To update http://bioconductor.org/packages/scater/ Transcriptomics, RNA, Visualization iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scater 1.22.0 bioconductor-scater 1.30.1 (0/5) (5/5) (5/5) True False -schicexplorer schicexplorer_schicadjustmatrix, schicexplorer_schiccluster, schicexplorer_schicclustercompartments, schicexplorer_schicclusterminhash, schicexplorer_schicclustersvl, schicexplorer_schicconsensusmatrices, schicexplorer_schiccorrectmatrices, schicexplorer_schiccreatebulkmatrix, schicexplorer_schicdemultiplex, schicexplorer_schicinfo, schicexplorer_schicmergematrixbins, schicexplorer_schicmergetoscool, schicexplorer_schicnormalize, schicexplorer_schicplotclusterprofiles, schicexplorer_schicplotconsensusmatrices, schicexplorer_schicqualitycontrol scHiCExplorer: Set of programs to process, analyze and visualize scHi-C data. To update https://github.com/joachimwolff/schicexplorer Sequence Analysis, Transcriptomics, Visualization schicexplorer iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/schicexplorer 4 schicexplorer 7 (0/16) (0/16) (16/16) True False -scikit-bio scikit_bio_diversity_beta_diversity scikit-bio: an open-source, BSD-licensed, python package providing data structures, algorithms, and educational resources for bioinformatics Up-to-date http://scikit-bio.org/ Sequence Analysis scikit_bio iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scikit_bio 0.4.2 scikit-bio 0.4.2 (1/1) (0/1) (0/1) True False -scoary 676.0 61.0 scoary Scoary calculates the assocations between all genes in the accessory genome and the traits. Up-to-date https://github.com/AdmiralenOla/Scoary Metagenomics scoary iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scoary 1.6.16 scoary 1.6.16 (0/1) (0/1) (1/1) True True -scpipe 628.0 11.0 scpipe A flexible preprocessing pipeline for single-cell RNA-sequencing data scpipe scPipe A preprocessing pipeline for single cell RNA-seq data that starts from the fastq files and produces a gene count matrix with associated quality control information. It can process fastq data generated by CEL-seq, MARS-seq, Drop-seq, Chromium 10x and SMART-seq protocols. Genome annotation, Validation, Alignment, Visualisation Gene expression, RNA-seq, Sequencing To update http://bioconductor.org/packages/release/bioc/html/scPipe.html Transcriptomics, RNA, Statistics scpipe iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scpipe 1.0.0+galaxy2 bioconductor-scpipe 2.2.0 (1/1) (0/1) (1/1) True False -semibin 183.0 10.0 semibin_bin, semibin_concatenate_fasta, semibin_generate_cannot_links, semibin_generate_sequence_features, semibin, semibin_train SemiBin: Semi-supervised Metagenomic Binning Using Siamese Neural Networks semibin SemiBin Command tool for metagenomic binning with semi-supervised deep learning using information from reference genomes. Sequence assembly, Read binning Metagenomics, Machine learning, Microbial ecology, Sequence assembly Up-to-date https://semibin.readthedocs.io/en/latest/ Metagenomics semibin iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/semibin 2.0.2 semibin 2.0.2 (0/6) (0/6) (6/6) True True -seq2hla 288.0 16.0 seq2hla Precision HLA typing and expression from RNAseq data seq2hla Seq2HLA seq2HLA is a computational tool to determine Human Leukocyte Antigen (HLA) directly from existing and future short RNA-Seq reads. It takes standard RNA-Seq sequence reads in fastq format as input, uses a bowtie index comprising known HLA alleles and outputs the most likely HLA class I and class II types, a p-value for each call, and the expression of each class. Read mapping, Genetic variation analysis Transcriptomics, Mapping Up-to-date https://github.com/TRON-Bioinformatics/seq2HLA Sequence Analysis seq2hla iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seq2hla 2.3 seq2hla 2.3 (0/1) (0/1) (1/1) True False -seqcomplexity 68.0 16.0 seqcomplexity Sequence complexity for raw reads Up-to-date https://github.com/stevenweaver/seqcomplexity Sequence Analysis iuc https://github.com/stephenshank/tools-iuc/tree/seqcomplexity/tools/seqcomplexity/ 0.1.2 seqcomplexity 0.1.2 (1/1) (0/1) (1/1) True False -seqkit seqkit_fx2tab, seqkit_locate, seqkit_stats A cross-platform and ultrafast toolkit for FASTA/Q file manipulation seqkit seqkit FASTA and FASTQ are basic and ubiquitous formats for storing nucleotide and protein sequences. Common manipulations of FASTA/Q file include converting, searching, filtering, deduplication, splitting, shuffling, and sampling. Existing tools only implement some of these manipulations, and not particularly efficiently, and some are only available for certain operating systems. Furthermore, the complicated installation process of required packages and running environments can render these programs less user friendly. SeqKit demonstrates competitive performance in execution time and memory usage compared to similar tools. The efficiency and usability of SeqKit enable researchers to rapidly accomplish common FASTA/Q file manipulations. DNA transcription, Sequence trimming, DNA translation, Sequence conversion Database management, Sequence analysis To update https://bioinf.shenwei.me/seqkit/ Sequence Analysis seqkit iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqkit 2.3.1 seqkit 2.7.0 (0/3) (0/3) (3/3) True True -seqprep seqprep Tool for merging paired-end Illumina reads and trimming adapters. seqprep SeqPrep Strips adapters and optionally merges overlapping paired-end (or paired-end contamination in mate-pair libraries) illumina style reads. Nucleic acid design Genomics, Sequence assembly, Sequencing, Probes and primers Up-to-date https://github.com/jstjohn/SeqPrep Fastq Manipulation, Sequence Analysis seqprep iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqprep 1.3.2 seqprep 1.3.2 (0/1) (0/1) (1/1) False -seqsero2 12.0 seqsero2 Salmonella serotype prediction from genome sequencing data Up-to-date https://github.com/denglab/SeqSero2 Sequence Analysis seqsero2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqsero2 1.2.1 seqsero2 1.2.1 (0/1) (0/1) (1/1) False -seqtk 59668.0 753.0 seqtk_comp, seqtk_cutN, seqtk_dropse, seqtk_fqchk, seqtk_hety, seqtk_listhet, seqtk_mergefa, seqtk_mergepe, seqtk_mutfa, seqtk_randbase, seqtk_sample, seqtk_seq, seqtk_subseq, seqtk_telo, seqtk_trimfq Toolkit for processing sequences in FASTA/Q formats seqtk seqtk A tool for processing sequences in the FASTA or FASTQ format. It parses both FASTA and FASTQ files which can also be optionally compressed by gzip. Data handling, Sequence file editing Data management Up-to-date https://github.com/lh3/seqtk Sequence Analysis seqtk iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqtk 1.4 seqtk 1.4 (15/15) (15/15) (15/15) True False -seqwish 271.0 seqwish Alignment to variation graph inducer To update https://github.com/ekg/seqwish Sequence Analysis, Variant Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqwish/ 0.7.5 seqwish 0.7.9 (0/1) (0/1) (1/1) True False -seurat 1543.0 66.0 seurat A toolkit for quality control, analysis, and exploration of single cell RNA sequencing data To update https://github.com/satijalab/seurat Transcriptomics, RNA, Statistics seurat iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seurat 4.3.0.1 r-seurat 3.0.2 (1/1) (1/1) (1/1) True False -shasta 763.0 154.0 shasta Fast de novo assembly of long read sequencing data To update https://github.com/chanzuckerberg/shasta Assembly, Nanopore shasta iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/shasta 0.6.0 shasta 0.11.1 (0/1) (1/1) (1/1) True False -shorah shorah_amplicon Reconstruct haplotypes using ShoRAH in amplicon mode shorah ShoRAH Inference of a population from a set of short reads. The package contains programs that support mapping of reads to a reference genome, correcting sequencing errors by locally clustering reads in small windows of the alignment, reconstructing a minimal set of global haplotypes that explain the reads, and estimating the frequencies of the inferred haplotypes. Haplotype mapping, Variant calling Metagenomics, Sequencing, Genetics To update https://github.com/cbg-ethz/shorah/blob/master/README.md Sequence Analysis shorah_amplicon iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/shorah 1.1.3 shorah 1.99.2 (0/1) (0/1) (0/1) True False -shovill 41600.0 1008.0 shovill Faster de novo assembly pipeline based around Spades shovill shovill Shovill is a pipeline for assembly of bacterial isolate genomes from Illumina paired-end reads. Shovill uses SPAdes at its core, but alters the steps before and after the primary assembly step to get similar results in less time. Shovill also supports other assemblers like SKESA, Velvet and Megahit, so you can take advantage of the pre- and post-processing the Shovill provides with those too. Genome assembly Genomics, Microbiology, Sequence assembly Up-to-date https://github.com/tseemann/shovill Assembly shovill iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/shovill 1.1.0 shovill 1.1.0 (1/1) (1/1) (1/1) True True -sickle 14982.0 269.0 sickle A windowed adaptive trimming tool for FASTQ files using quality sickle sickle A tool that uses sliding windows along with quality and length thresholds to determine when quality is sufficiently low to trim the 3'-end of reads and also determines when the quality is sufficiently high enough to trim the 5'-end of reads. Sequence trimming Data quality management To update https://github.com/najoshi/sickle Fastq Manipulation, Sequence Analysis sickle iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sickle 1.33.2 sickle-trim 1.33 (1/1) (0/1) (1/1) True False -sina 1128.0 42.0 sina SINA reference based multiple sequence alignment sina SINA Aligns and optionally taxonomically classifies your rRNA gene sequences.Reference based multiple sequence alignment Sequence alignment analysis, Multiple sequence alignment, Taxonomic classification, Structure-based sequence alignment Sequencing, RNA, Nucleic acid structure analysis, Taxonomy, Sequence analysis, Taxonomy Up-to-date https://sina.readthedocs.io/en/latest/ Sequence Analysis sina iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sina 1.7.2 sina 1.7.2 (1/1) (0/1) (1/1) True False -sinto sinto_barcode, sinto_fragments Sinto single-cell analysis tools To update https://github.com/timoast/sinto Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sinto 0.9.0 sinto 0.10.0 (2/2) (0/2) (2/2) True False -slamdunk 361.0 2.0 alleyoop, slamdunk Slamdunk maps and quantifies SLAMseq reads Up-to-date http://t-neumann.github.io/slamdunk RNA, Transcriptomics, Sequence Analysis, Next Gen Mappers slamdunk iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/slamdunk 0.4.3 slamdunk 0.4.3 (2/2) (0/2) (2/2) True False -sleuth 64.0 8.0 sleuth Sleuth is a program for differential analysis of RNA-Seq data. sleuth sleuth A statistical model and software application for RNA-seq differential expression analysis. Expression data visualisation, Differential gene expression analysis, Gene expression profiling, Statistical calculation RNA-seq, Gene expression, Statistics and probability Up-to-date https://github.com/pachterlab/sleuth Transcriptomics, RNA, Statistics sleuth iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sleuth 0.30.1 r-sleuth 0.30.1 (0/1) (0/1) (1/1) True False -smallgenomeutilities smgu_frameshift_deletions_checks Set of utilities for manipulating small viral genome data. v-pipe V-pipe Bioinformatics pipeline for the analysis of next-generation sequencing data derived from intra-host viral populations. Read pre-processing, Sequence alignment, Genetic variation analysis Genomics, Population genetics, Workflows, Virology, Sequencing Up-to-date https://github.com/cbg-ethz/smallgenomeutilities Sequence Analysis smallgenomeutilities iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/smallgenomeutilities 0.4.0 smallgenomeutilities 0.4.0 (0/1) (0/1) (1/1) True True -smudgeplot 203.0 22.0 smudgeplot Inference of ploidy and heterozygosity structure using whole genome sequencing smudgeplots Smudgeplots Reference-free profiling of polyploid genomes | Inference of ploidy and heterozygosity structure using whole genome sequencing data | Smudgeplots are computed from raw or even better from trimmed reads and show the haplotype structure using heterozygous kmer pairs. For example: | This tool extracts heterozygous kmer pairs from kmer dump files and performs gymnastics with them. We are able to disentangle genome structure by comparing the sum of kmer pair coverages (CovA + CovB) to their relative coverage (CovA / (CovA + CovB)). Such an approach also allows us to analyze obscure genomes with duplications, various ploidy levels, etc | GenomeScope 2.0 and Smudgeplots: Reference-free profiling of polyploid genomes Timothy Rhyker Ranallo-Benavidez, Kamil S. Jaron, Michael C. Schatz bioRxiv 747568; doi: https://doi.org/10.1101/747568 Sequence trimming, Genotyping, k-mer counting Sequence assembly, Genetic variation, Mathematics Up-to-date https://github.com/KamilSJaron/smudgeplot Assembly smudgeplot galaxy-australia https://github.com/galaxyproject/tools-iuc 0.2.5 smudgeplot 0.2.5 (1/1) (1/1) (1/1) True False -snap snap, snap_training SNAP is a general purpose gene finding program suitable for both eukaryotic and prokaryotic genomes. snap SNAP The Semi-HMM-based Nucleic Acid Parser is a gene prediction tool. Gene prediction DNA, DNA polymorphism, Genetics Up-to-date https://github.com/KorfLab/SNAP Sequence Analysis snap iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/snap 2013_11_29 snap 2013_11_29 (1/2) (1/2) (1/2) True True -sniffles 919.0 58.0 sniffles Galaxy wrapper for sniffles sniffles Sniffles An algorithm for structural variation detection from third generation sequencing alignment. Sequence analysis, Structural variation detection DNA structural variation, Sequencing To update https://github.com/fritzsedlazeck/Sniffles Sequence Analysis sniffles iuc https://github.com/galaxyproject/tools-iuc 1.0.12 sniffles 2.2 (1/1) (1/1) (1/1) True False -snipit 669.0 22.0 snipit Summarise snps relative to a reference sequence snipit snipit Summarise snps relative to a reference sequence Base position variability plotting Virology Up-to-date https://github.com/aineniamh/snipit Variant Analysis, Sequence Analysis snipit iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/snipit 1.2 snipit 1.2 (0/1) (0/1) (1/1) True False -snippy 105708.0 1372.0 snippy_core, snippy, snippy_clean_full_aln Contains the snippy tool for characterising microbial snps snippy snippy Rapid haploid variant calling and core SNP phylogeny generation. Phylogenetic tree visualisation, Phylogenetic tree generation, Variant calling Genomics, Model organisms, DNA polymorphism, Phylogenetics To update https://github.com/tseemann/snippy Sequence Analysis snippy iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/snippy snippy 4.6.0 (3/3) (3/3) (3/3) True True -socru 621.0 13.0 socru Order and orientation of complete bacterial genomes To update https://github.com/quadram-institute-bioscience/socru Sequence Analysis socru iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/socru 2.1.7 socru 2.2.4 (1/1) (0/1) (1/1) True False -sonneityping 1.0 1.0 sonneityping Scripts for parsing Mykrobe predict results for Shigella sonnei. Up-to-date https://github.com/katholt/sonneityping Sequence Analysis sonneityping iuc https://github.com/katholt/sonneityping 20210201 sonneityping 20210201 (0/1) (0/1) (1/1) True True -spades 58834.0 2309.0 spades_biosyntheticspades, spades_coronaspades, spades_metaplasmidspades, metaspades, spades_metaviralspades, spades_plasmidspades, rnaspades, spades_rnaviralspades, spades SPAdes is an assembly toolkit containing various assembly pipelines. It implements the following 4 stages: assembly graph construction, k-bimer adjustment, construction of paired assembly graph and contig construction. biosyntheticspades biosyntheticSPAdes biosyntheticSPAdes - biosynthetic gene cluster assembly with paired-end reads Sequence assembly Sequence assembly, Sequence sites, features and motifs, Genetic engineering Up-to-date https://github.com/ablab/spades Assembly, RNA, Metagenomics spades iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/spades 3.15.5 spades 3.15.5 (9/9) (9/9) (9/9) True True -spaln 446.0 34.0 list_spaln_tables, spaln Spaln (space-efficient spliced alignment) maps and aligns a set of cDNA or protein sequences onto a whole genomic sequence. To update http://www.genome.ist.i.kyoto-u.ac.jp/~aln_user/spaln/ Sequence Analysis, Genome annotation spaln iuc https://github.com/ogotoh/spaln 2.4.9 python (2/2) (0/2) (2/2) True False -spotyping 1278.0 12.0 spotyping SpoTyping allows fast and accurate in silico Mycobacterium spoligotyping from sequence reads spotyping SpoTyping Fast and accurate in silico Mycobacterium spoligotyping from sequence reads. Variant pattern analysis Microbiology, Sequencing, Sequence composition, complexity and repeats, Genetic variation Up-to-date https://github.com/xiaeryu/SpoTyping-v2.0 Sequence Analysis spotyping iuc https://github.com/xiaeryu/SpoTyping-v2.0/tree/master/SpoTyping-v2.0-commandLine 2.1 spotyping 2.1 (0/1) (0/1) (1/1) True True -srst2 205.0 22.0 srst2 SRST2 Short Read Sequence Typing for Bacterial Pathogens To update http://katholt.github.io/srst2/ Metagenomics srst2 iuc https://github.com/katholt/srst2 0.2.0 samtools 1.19.2 (0/1) (0/1) (1/1) True True -stacks stacks_assembleperead, stacks_clonefilter, stacks_cstacks, stacks_denovomap, stacks_genotypes, stacks_populations, stacks_procrad, stacks_pstacks, stacks_refmap, stacks_rxstacks, stacks_sstacks, stacks_stats, stacks_ustacks Stacks is a software pipeline for building loci from short-read sequences, such as RAD-seq stacks Stacks Developed to work with restriction enzyme based sequence data, such as RADseq, for building genetic maps and conducting population genomics and phylogeography analysis. Data handling Mapping, Population genetics To update http://catchenlab.life.illinois.edu/stacks/ Sequence Analysis stacks iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/stacks stacks 2.65 (0/13) (13/13) (13/13) True False -stacks2 stacks2_clonefilter, stacks2_cstacks, stacks2_denovomap, stacks2_gstacks, stacks2_kmerfilter, stacks2_populations, stacks2_procrad, stacks2_refmap, stacks2_shortreads, stacks2_sstacks, stacks2_tsv2bam, stacks2_ustacks Stacks is a software pipeline for building loci from short-read sequences, such as RAD-seq To update http://catchenlab.life.illinois.edu/stacks/ Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/stacks2 2.55 stacks 2.65 (0/12) (12/12) (12/12) True False -star_fusion 1212.0 35.0 star_fusion STAR Fusion detects fusion genes in RNA-Seq data after running RNA-STAR To update Sequence Analysis, Transcriptomics star_fusion iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/star_fusion 0.5.4-3+galaxy1 star-fusion 1.12.0 (1/1) (1/1) (1/1) True False -structure 2623.0 59.0 structure for using multi-locus genotype data to investigate population structure. structure Structure The program structureis a free software package for using multi-locus genotype data to investigate population structure. Its uses include inferring the presence of distinct populations, assigning individuals to populations, studying hybrid zones, identifying migrants and admixed individuals, and estimating population allele frequencies in situations where many individuals are migrants or admixed. Genetic variation analysis Population genetics Up-to-date Phylogenetics, Variant Analysis structure iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/structure 2.3.4 structure 2.3.4 (0/1) (0/1) (1/1) True True -structureharvester structureharvester for parsing STRUCTURE outputs and for performing the Evanno method Up-to-date Phylogenetics, Variant Analysis structureharvester iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/structureharvester 0.6.94 structureharvester 0.6.94 (0/1) (0/1) (0/1) True False -syndiva 30.0 2.0 syndiva SynDivA was developed to analyze the diversity of synthetic libraries of a Fibronectin domain. To update Proteomics syndiva iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/SynDivA 1.0 clustalo 1.2.4 (0/1) (0/1) (1/1) True False -tasmanian_mismatch tasmanian_mismatch Analysis of positional mismatches Up-to-date Sequence Analysis tasmanian_mismatch iuc https://github.com/nebiolabs/tasmanian-mismatch 1.0.7 tasmanian-mismatch 1.0.7 (0/1) (0/1) (0/1) True False -taxonomy_filter_refseq taxonomy_filter_refseq Filter RefSeq by taxonomy To update https://github.com/pvanheus/ncbitaxonomy Sequence Analysis, Genome annotation taxonomy_filter_refseq iuc https://github.com/galaxyproject/tools-iuc 0.3.0 rust-ncbitaxonomy 1.0.7 (0/1) (0/1) (0/1) True False -taxonomy_krona_chart 27426.0 1801.0 taxonomy_krona_chart Krona pie chart from taxonomic profile krona Krona Krona creates interactive HTML5 charts of hierarchical data (such as taxonomic abundance in a metagenome). Visualisation Metagenomics To update http://sourceforge.net/projects/krona/ Assembly taxonomy_krona_chart crs4 https://github.com/galaxyproject/tools-iuc/tree/master/tools/taxonomy_krona_chart 2.7.1+galaxy0 krona 2.8.1 (1/1) (1/1) (1/1) True True -tb-profiler tb_profiler_profile Processes M. tuberculosis sequence data to infer strain type and identify known drug resistance markers. To update https://github.com/jodyphelan/TBProfiler Sequence Analysis tbprofiler iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/tb-profiler 4.4.1 tb-profiler 5.0.1 (1/1) (1/1) (1/1) True True -tbl2gff3 1584.0 229.0 tbl2gff3 Table to GFF3 To update https://github.com/galaxyproject/tools-iuc/tree/master/tools/tbl2gff3 Convert Formats, Sequence Analysis tbl2gff3 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/tbl2gff3 1.2 bcbiogff 0.6.6 (0/1) (1/1) (1/1) True False -te_finder 81.0 7.0 te_finder Transposable element insertions finder tefinder TEfinder A Bioinformatics Pipeline for Detecting New Transposable Element Insertion Events in Next-Generation Sequencing Data.A bioinformatics tool for detecting novel transposable element insertions.TEfinder uses discordant reads to detect novel transposable element insertion events in paired-end sample sequencing data. Genome indexing, Variant calling, PCR primer design Sequencing, Mobile genetic elements, Workflows, Evolutionary biology, Genetic variation To update https://github.com/VistaSohrab/TEfinder Sequence Analysis te_finder iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/te_finder/ 1.0.1 samtools 1.19.2 (0/1) (0/1) (1/1) True False -telescope telescope_assign Single locus resolution of Transposable ELEment expression. Telescope-expression Telescope Telescope is a tool for the characterization of the retrotranscriptome by accurate estimation of transposable element expression and the quantification of transposable element expression using RNA-seq.It can be used for Statistical Performance of TE Quantification Methods.All scripts needed to examine the sensitivity and biases of computational approaches for quantifying TE expression: 1) unique counts, 2) best counts, 3) RepEnrich, 4) TEtranscripts, 5) RSEM, 6) SalmonTE, and 7) Telescope. Essential dynamics, Sequence trimming, RNA-Seq quantification, Expression analysis, Read mapping RNA-Seq, Transcriptomics, Mapping, Gene transcripts, Sequence assembly Up-to-date https://github.com/mlbendall/telescope/ Genome annotation telescope_assign iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/telescope 1.0.3 telescope 1.0.3 (0/1) (0/1) (0/1) True False -tetoolkit tetoolkit_tetranscripts The TEToolkit suite improves the bioinformatic analysis of repetitive sequences, particularly transposable elements, in order to elucidate novel (and previously ignored) biological insights of their functions in development and diseases. Up-to-date http://hammelllab.labsites.cshl.edu/software/ Sequence Analysis tetoolkit iuc https://github.com/mhammell-laboratory/TEtranscripts 2.2.3 tetranscripts 2.2.3 (0/1) (1/1) (1/1) True False -tetyper 69.0 8.0 tetyper Type a specific transposable element (TE) of interest from paired-end sequencing data. Up-to-date https://github.com/aesheppard/TETyper Sequence Analysis tetyper iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/tetyper 1.1 tetyper 1.1 (1/1) (0/1) (1/1) True False -tn93 113.0 7.0 tn93_readreduce, tn93, tn93_cluster, tn93_filter Compute distances between sequences To update https://github.com/veg/tn93/ Sequence Analysis tn93 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/tn93/ 1.0.6 tn93 1.0.13 (4/4) (0/4) (4/4) True False -transdecoder 5468.0 348.0 transdecoder TransDecoder finds coding regions within transcripts TransDecoder TransDecoder TransDecoder identifies candidate coding regions within transcript sequences, such as those generated by de novo RNA-Seq transcript assembly using Trinity, or constructed based on RNA-Seq alignments to the genome using Tophat and Cufflinks. Coding region prediction, de Novo sequencing, De-novo assembly Genomics, Gene transcripts, RNA-Seq, Gene expression, Sequence assembly, Whole genome sequencing To update https://transdecoder.github.io/ Transcriptomics, RNA transdecoder iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/transdecoder 5.5.0 transdecoder 5.7.1 (1/1) (1/1) (1/1) True False -transit gff_to_prot, transit_gumbel, transit_hmm, transit_resampling, transit_tn5gaps TRANSIT transit TRANSIT A tool for the analysis of Tn-Seq data. It provides an easy to use graphical interface and access to three different analysis methods that allow the user to determine essentiality in a single condition as well as between conditions. Transposon prediction DNA, Sequencing, Mobile genetic elements To update https://github.com/mad-lab/transit/ Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/transit/ 3.0.2 transit 3.2.3 (5/5) (5/5) (5/5) True False -transtermhp 229.0 5.0 transtermhp Finds rho-independent transcription terminators in bacterial genomes To update Sequence Analysis transtermhp iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/transtermhp transtermhp 2.09 (1/1) (0/1) (1/1) True True -trinity 12733.0 678.0 trinity_abundance_estimates_to_matrix, trinity_align_and_estimate_abundance, trinity_analyze_diff_expr, trinity_contig_exn50_statistic, trinity_define_clusters_by_cutting_tree, describe_samples, trinity_filter_low_expr_transcripts, trinity_gene_to_trans_map, trinity_run_de_analysis, trinity_samples_qccheck, trinity_super_transcripts, trinity, trinity_stats Trinity represents a method for the efficient and robust de novo reconstruction of transcriptomes from RNA-seq datahttps://github.com/trinityrnaseq/trinityrnaseq trinity Trinity Trinity is a transcriptome assembler which relies on three different tools, inchworm an assembler, chrysalis which pools contigs and butterfly which amongst others compacts a graph resulting from butterfly with reads. Transcriptome assembly Transcriptomics, Gene expression, Gene transcripts Up-to-date https://github.com/trinityrnaseq/trinityrnaseq Transcriptomics, RNA iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/trinity 2.15.1 trinity 2.15.1 (9/13) (13/13) (13/13) True False -trinotate 1796.0 151.0 trinotate Trinotate is a comprehensive annotation suite designed for automatic functional annotation of de novo transcriptomes. trinotate Trinotate Comprehensive annotation suite designed for automatic functional annotation of transcriptomes, particularly de novo assembled transcriptomes, from model or non-model organisms. Gene functional annotation Gene expression, Transcriptomics To update https://trinotate.github.io/ Transcriptomics, RNA trinotate iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/trinotate 3.2.2 trinotate 4.0.2 (1/1) (1/1) (1/1) True False -trycycler trycycler_cluster, trycycler_consensus, trycycler_partition, trycycler_reconcile_msa, trycycler_subsample Trycycler toolkit wrappers Up-to-date https://github.com/rrwick/Trycycler Assembly trycycler iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/trycycler 0.5.4 trycycler 0.5.4 (0/5) (5/5) (5/5) True False -tsebra 5.0 tsebra This tool has been developed to combine BRAKER predictions. Up-to-date https://github.com/Gaius-Augustus/TSEBRA Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/tsebra 1.1.2.3 tsebra 1.1.2.3 (0/1) (0/1) (1/1) True False -ucsc_blat ucsc_blat Standalone blat sequence search command line tool blat BLAT Fast, accurate spliced alignment of DNA sequences. Sequence alignment Sequence analysis To update http://genome.ucsc.edu/goldenPath/help/blatSpec.html Sequence Analysis ucsc_blat yating-l 377 ucsc-blat 445 (0/1) (0/1) (0/1) True False -umi_tools umi_tools_count, umi_tools_dedup, umi_tools_extract, umi_tools_group, umi_tools_whitelist UMI-tools extract - Extract UMIs from fastq umi-tools UMI-tools Tools for handling Unique Molecular Identifiers in NGS data sets. Sequencing quality control NGS, Sequence sites, features and motifs, Quality affairs To update https://github.com/CGATOxford/UMI-tools Sequence Analysis, Transcriptomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/umi_tools 1.1.2 umi_tools 1.1.5 (5/5) (5/5) (5/5) True False -unicycler 65732.0 1558.0 unicycler Unicycler is a hybrid assembly pipeline for bacterial genomes. unicycler Unicycler A tool for assembling bacterial genomes from a combination of short (2nd generation) and long (3rd generation) sequencing reads. Genome assembly, Aggregation Microbiology, Genomics, Sequencing, Sequence assembly Up-to-date https://github.com/rrwick/Unicycler Assembly unicycler iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/unicycler 0.5.0 unicycler 0.5.0 (1/1) (1/1) (1/1) True True -usher 1060.0 5.0 usher_matutils, usher UShER toolkit wrappers To update https://github.com/yatisht/usher Phylogenetics usher iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/usher 0.2.1 usher 0.6.3 (0/2) (0/2) (2/2) True True -valet 637.0 20.0 valet A pipeline for detecting mis-assemblies in metagenomic assemblies. To update https://github.com/marbl/VALET Metagenomics valet iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/valet valet 1.0 (1/1) (0/1) (1/1) True True -vapor 3164.0 94.0 vapor Classify Influenza samples from raw short read sequence data vapor VAPOR VAPOR is a tool for classification of Influenza samples from raw short read sequence data for downstream bioinformatics analysis. VAPOR is provided with a fasta file of full-length sequences (> 20,000) for a given segment, a set of reads, and attempts to retrieve a reference that is closest to the sample strain. Data retrieval, De-novo assembly, Read mapping Whole genome sequencing, Mapping, Sequence assembly Up-to-date https://github.com/connor-lab/vapor Sequence Analysis vapor iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vapor 1.0.2 vapor 1.0.2 (1/1) (0/1) (1/1) True True -varvamp varvamp Variable VirusAMPlicons (varVAMP) is a tool to design primers for highly diverse viruses varvamp varVAMP variable VirusAMPlicons (varVAMP) is a tool to design primers for highly diverse viruses. The input is an alignment of your viral (full-genome) sequences. PCR primer design Virology Up-to-date https://github.com/jonas-fuchs/varVAMP/ Sequence Analysis varvamp iuc https://github.com/jonas-fuchs/varVAMP 1.1.1 varvamp 1.1.1 (0/1) (0/1) (1/1) False -vegan vegan_diversity, vegan_fisher_alpha, vegan_rarefaction To update https://cran.r-project.org/package=vegan Metagenomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vegan/ 2.4-3 r-vegan 2.3_4 (3/3) (0/3) (3/3) True True -velvet 12218.0 1280.0 velvetg, velveth de novo genomic assembler specially designed for short read sequencing technologies velvet Velvet A de novo genomic assembler specially designed for short read sequencing technologies, such as Solexa or 454 or SOLiD. Formatting, De-novo assembly Sequence assembly To update https://www.ebi.ac.uk/~zerbino/velvet/ Assembly velvet devteam https://github.com/galaxyproject/tools-iuc/tree/master/tools/velvet velvet 1.2.10 (2/2) (2/2) (2/2) True True -velvet_optimiser velvetoptimiser Automatically optimize Velvet assemblies velvetoptimiser VelvetOptimiser This tool is designed to run as a wrapper script for the Velvet assembler (Daniel Zerbino, EBI UK) and to assist with optimising the assembly. Optimisation and refinement, Sequence assembly Genomics, Sequence assembly To update Assembly velvetoptimiser simon-gladman https://github.com/galaxyproject/tools-iuc/tree/master/tools/velvetoptimiser 2.2.6+galaxy2 velvet 1.2.10 (1/1) (1/1) (1/1) True True -verkko 22.0 9.0 verkko Telomere-to-telomere assembly pipeline To update https://github.com/marbl/verkko Assembly verkko iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/verkko 1.3.1 verkko 2.0 (0/1) (0/1) (1/1) True False -vg vg_convert, vg_deconstruct, vg_view Variation graph data structures, interchange formats, alignment, genotyping, and variant calling methods To update https://github.com/vgteam/vg Sequence Analysis, Variant Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vg 1.23.0 vg 1.55.0 (0/3) (0/3) (3/3) True False -volcanoplot 30946.0 1749.0 volcanoplot Tool to create a Volcano Plot To update Visualization, Transcriptomics, Statistics volcanoplot iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/volcanoplot 0.0.5 r-ggplot2 2.2.1 (1/1) (1/1) (1/1) True False -vsearch 8507.0 182.0 vsearch_alignment, vsearch_chimera_detection, vsearch_clustering, vsearch_dereplication, vsearch_masking, vsearch_search, vsearch_shuffling, vsearch_sorting VSEARCH including searching, clustering, chimera detection, dereplication, sorting, masking and shuffling of sequences. vsearch VSEARCH High-throughput search and clustering sequence analysis tool. It supports de novo and reference based chimera detection, clustering, full-length and prefix dereplication, reverse complementation, masking, all-vs-all pairwise global alignment, exact and global alignment searching, shuffling, subsampling and sorting. It also supports FASTQ file analysis, filtering and conversion. DNA mapping, Chimera detection Metagenomics, Sequence analysis To update https://github.com/torognes/vsearch Sequence Analysis vsearch iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vsearch 2.8.3 vsearch 2.27.0 (8/8) (8/8) (8/8) True True -vsnp vsnp_add_zero_coverage, vsnp_build_tables, vsnp_determine_ref_from_data, vsnp_get_snps, vsnp_statistics The vSNP tools are critical components of several workflows that validate SNPs and produce annotatedSNP tables and corresponding phylogenetic trees. To update https://github.com/USDA-VS/vSNP Sequence Analysis vsnp iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vsnp 3.0.6 pysam 0.22.0 (0/5) (0/5) (0/5) True False -weather_app simple_weather provides simple weather in text format To update http://wttr.in/ Visualization, Web Services simpleweather iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/weather_app 0.1.2 curl (0/1) (0/1) (0/1) True False -windowmasker 85.0 windowmasker_mkcounts, windowmasker_ustat Identify repetitive regions using WindowMasker To update https://www.ncbi.nlm.nih.gov/IEB/ToolBox/CPP_DOC/lxr/source/src/app/winmasker/ Sequence Analysis windowmasker iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/windowmasker/ 1.0 blast 2.15.0 (0/2) (2/2) (2/2) False -yahs 344.0 64.0 yahs Yet Another Hi-C scaffolding tool Up-to-date https://github.com/c-zhou/yahs Assembly yahs iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/yahs 1.2a.2 yahs 1.2a.2 (1/1) (1/1) (1/1) True False -bamtools 14039.0 208.0 bamtools Operate on and transform BAM datasets in various ways using bamtools Up-to-date https://github.com/pezmaster31/bamtools Sequence Analysis, SAM bamtools devteam https://github.com/galaxyproject/tools-iuc/tree/main/tool_collections/bamtools/bamtools 2.5.2 bamtools 2.5.2 (1/1) (0/1) (1/1) True True -bamtools_filter 114845.0 1195.0 bamFilter Filter BAM datasets on various attributes using bamtools filter Up-to-date https://github.com/pezmaster31/bamtools Sequence Analysis, SAM bamtools_filter devteam https://github.com/galaxyproject/tools-iuc/tree/main/tool_collections/bamtools/bamtools_filter 2.5.2 bamtools 2.5.2 (1/1) (1/1) (1/1) True False -bamtools_split 1434.0 47.0 bamtools_split_mapped, bamtools_split_paired, bamtools_split_ref, bamtools_split_tag Up-to-date https://github.com/pezmaster31/bamtools Sequence Analysis, SAM iuc https://github.com/galaxyproject/tools-iuc/tree/main/tool_collections/bamtools/bamtools_split 2.5.2 bamtools 2.5.2 (4/4) (2/4) (4/4) True False -biotradis bacteria_tradis, tradis_essentiality, tradis_gene_insert_sites Bio-Tradis is a tool suite dedicated to essentiality analyses with TraDis data. Up-to-date https://www.sanger.ac.uk/science/tools/bio-tradis Genome annotation biotradis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tool_collections/biotradis 1.4.5 biotradis 1.4.5 (3/3) (0/3) (0/3) True True -kraken 13938.0 404.0 kraken-filter, kraken-mpa-report, kraken-report, kraken-translate, kraken Kraken is a system for assigning taxonomic labels to short DNAsequences, usually obtained through metagenomic studies. Previous attempts by otherbioinformatics software to accomplish this task have often used sequence alignmentor machine learning techniques that were quite slow, leading to the developmentof less sensitive but much faster abundance estimation programs. Kraken aims toachieve high sensitivity and high speed by utilizing exact alignments of k-mersand a novel classification algorithm. To update http://ccb.jhu.edu/software/kraken/ Metagenomics kraken devteam https://github.com/galaxyproject/tools-iuc/blob/master/tool_collections/kraken/ kraken 1.1.1 (5/5) (5/5) (5/5) True True -kraken2 185308.0 2367.0 kraken2 Kraken2 for taxonomic designation. kraken2 kraken2 Kraken 2 is the newest version of Kraken, a taxonomic classification system using exact k-mer matches to achieve high accuracy and fast classification speeds. This classifier matches each k-mer within a query sequence to the lowest common ancestor (LCA) of all genomes containing the given k-mer. The k-mer assignments inform the classification algorithm. Taxonomic classification Taxonomy, Metagenomics To update http://ccb.jhu.edu/software/kraken/ Metagenomics kraken2 iuc https://github.com/galaxyproject/tools-iuc/blob/master/tool_collections/kraken2/kraken2/ 2.1.1 kraken2 2.1.3 (1/1) (1/1) (1/1) True True -ThermoRawFileParser thermo_raw_file_converter Thermo RAW file converter To update https://github.com/compomics/ThermoRawFileParser Proteomics thermo_raw_file_converter galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/ThermoRawFileParser 1.3.4 thermorawfileparser 1.4.3 (0/1) (1/1) (1/1) True False -bed_to_protein_map 385.0 49.0 bed_to_protein_map Converts a BED file to a tabular list of exon locations To update Proteomics bed_to_protein_map galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/bed_to_protein_map 0.2.0 python (1/1) (1/1) (1/1) True False -blast_plus_remote_blastp blast_plus_remote_blastp NCBI BLAST+ with -remote option To update https://blast.ncbi.nlm.nih.gov/ Sequence Analysis blast_plus_remote_blastp galaxyp https://github.com/peterjc/galaxy_blast/tree/master/tools/ncbi_blast_plus 2.6.0 blast 2.15.0 (0/1) (0/1) (0/1) True False -bumbershoot idpqonvertEmbedder, idpassemble, idpqonvert, idpquery, myrimatch To update http://proteowizard.sourceforge.net/ Proteomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/bumbershoot 3.0.21142 bumbershoot 3_0_21142_0e4f4a4 (0/5) (0/5) (5/5) True False -calisp calisp Calgary approach to isotopes in proteomics Up-to-date https://github.com/kinestetika/Calisp/ Proteomics calisp galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/calisp 3.0.13 calisp 3.0.13 (0/1) (0/1) (1/1) True False -cardinal cardinal_classification, cardinal_colocalization, cardinal_combine, cardinal_data_exporter, cardinal_filtering, cardinal_mz_images, cardinal_preprocessing, cardinal_quality_report, cardinal_segmentations, cardinal_single_ion_segmentation, cardinal_spectra_plots Statistical and computational tools for analyzing mass spectrometry imaging datasets To update http://cardinalmsi.org Proteomics, Metabolomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/cardinal 2.10.0 bioconductor-cardinal 3.4.3 (0/11) (9/11) (11/11) True False -dbbuilder 4758.0 161.0 dbbuilder Protein Database Downloader To update https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/dbbuilder Proteomics dbbuilder galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/dbbuilder 0.3.4 wget (0/1) (1/1) (1/1) True False -decoyfasta 104.0 15.0 Galaxy tool wrapper for the transproteomic pipeline decoyFASTA tool. To update Proteomics decoyfasta galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/decoyfasta (0/1) (0/1) (0/1) True False -dia_umpire 33.0 2.0 dia_umpire_se DIA-Umpire analysis for data independent acquisition (DIA) mass spectrometry-based proteomics To update http://diaumpire.sourceforge.net/ Proteomics dia_umpire galaxyp https://github.com/galaxyproject/tools-iuc/tree/master/tools/dia_umpire 2.1.3 dia_umpire 2.1.6 (0/1) (1/1) (1/1) True False -dialignr 40.0 1.0 dialignr DIAlignR is an R package for retention time alignment of targeted mass spectrometric data, including DIA and SWATH-MS data. This tool works with MS2 chromatograms directly and uses dynamic programming for alignment of raw chromatographic traces. DIAlignR uses a hybrid approach of global (feature-based) and local (raw data-based) alignment to establish correspondence between peaks. To update https://github.com/shubham1637/DIAlignR Proteomics dialignr galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/dialignr 1.2.0 bioconductor-dialignr 2.10.0 (0/1) (0/1) (1/1) True False -diann 15.0 3.0 diann DiaNN (DIA-based Neural Networks) is a software for DIA/SWATH data processing. To update https://github.com/vdemichev/DiaNN Proteomics diann galaxyp https://github.com/vdemichev/DiaNN 1.8.1 (0/1) (1/1) (1/1) True False -diapysef 245.0 11.0 diapysef diapysef is a convenience package for working with DIA-PASEF data To update https://pypi.org/project/diapysef/ Proteomics diapysef galaxyp https://github.com/galaxyproject/tools-iuc/tree/master/tools/diapysef 0.3.5.0 diapysef 1.0.10 (0/1) (1/1) (1/1) True False -diffacto 7.0 5.0 diffacto Diffacto comparative protein abundance estimation Up-to-date https://github.com/statisticalbiotechnology/diffacto Proteomics diffacto galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/diffacto 1.0.6 diffacto 1.0.6 (0/1) (0/1) (1/1) True False -data_manager_eggnog_mapper 9.0 2.0 downloads eggnog data for eggnog-mapper To update Proteomics data_manager_eggnog_mapper galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/eggnog_mapper/eggnog_mapper_data_manager (0/1) (0/1) (0/1) True False -data_manager_eggnog_mapper_abspath 1.0 download eggnog data for eggnog-mapper To update Proteomics data_manager_eggnog_mapper_abspath galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/eggnog_mapper/data_manager_eggnog_mapper_abspath (0/1) (0/1) (0/1) True False -eggnog_mapper 30565.0 510.0 eggnog_mapper, eggnog_mapper_annotate, eggnog_mapper_search eggnog-mapper fast functional annotation of novel sequences eggnog-mapper-v2 eggNOG-mapper v2 EggNOG-mapper is a tool for fast functional annotation of novel sequences. It uses precomputed orthologous groups and phylogenies from the eggNOG database (http://eggnog5.embl.de) to transfer functional information from fine-grained orthologs only. Homology-based gene prediction, Genome annotation, Fold recognition, Information extraction, Query and retrieval Metagenomics, Phylogeny, Transcriptomics, Workflows, Sequence analysis To update Proteomics eggnog_mapper galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/eggnog_mapper/eggnog_mapper 2.1.8 eggnog-mapper 2.1.12 (1/3) (3/3) (3/3) True True -encyclopedia encyclopedia_encyclopedia, encyclopedia_fasta_to_prosit_csv, encyclopedia_library_to_blib, encyclopedia_prosit_csv_to_library, encyclopedia_quantify, encyclopedia_searchtolib, encyclopedia_walnut Mass Spec Data-Independent Acquisition (DIA) MS/MS analysis To update https://bitbucket.org/searleb/encyclopedia/wiki/Home Proteomics encyclopedia galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/encyclopedia/tools/encyclopedia 1.12.34 encyclopedia 2.12.30 (2/7) (4/7) (7/7) True False -fastg2protlib 28.0 1.0 fastg2protlib-peptides, fastg2protlib-validate Generate FASTA from FASTG To update https://github.com/galaxyproteomics/fastg2protlib.git Proteomics fastg2protlib galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/fastg2protlib 1.0.2 (0/2) (0/2) (2/2) True False -feature_alignment 18.0 1.0 feature_alignment TRIC integrates information from all available runs via a graph-based alignment strategy Up-to-date Proteomics feature_alignment galaxyp https://github.com/msproteomicstools/msproteomicstools/blob/master/TRIC-README.md 0.11.0 msproteomicstools 0.11.0 (0/1) (0/1) (1/1) True False -filter_by_fasta_ids 26274.0 426.0 filter_by_fasta_ids Filter FASTA on the headers and/or the sequences To update Fasta Manipulation, Proteomics filter_by_fasta_ids galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/filter_by_fasta_ids 2.3 python (1/1) (1/1) (1/1) True False -flashlfq 645.0 17.0 flashlfq FlashLFQ mass-spectrometry proteomics label-free quantification To update https://github.com/smith-chem-wisc/FlashLFQ Proteomics flashlfq galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/flashlfq 1.0.3.1 flashlfq 1.2.6 (0/1) (1/1) (1/1) True False -hardklor 111.0 2.0 hardklor, kronik Hardklör To update Proteomics hardklor galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/hardklor 2.30.1+galaxy1 hardklor 2.3.2 (0/2) (0/2) (2/2) True False -idconvert 122.0 3.0 idconvert Convert mass spectrometry identification files on linux or MacOSX To update Proteomics idconvert galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msconvert proteowizard 3_0_9992 (0/1) (0/1) (1/1) True False -lfq_protein_quant 111.0 3.0 lfq_protein_quant Enable protein summarisation and quantitation To update https://github.com/compomics/LFQ_galaxy_p Proteomics lfq_protein_quant galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/lfq_protein_quant 1.0 bioconductor-msnbase 2.28.1 (0/1) (0/1) (1/1) True False -maldiquant maldi_quant_peak_detection, maldi_quant_preprocessing MALDIquant provides a complete analysis pipeline for MALDI-TOF and other 2D mass spectrometry data. To update http://strimmerlab.org/software/maldiquant/ Proteomics MALDIquant galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/MALDIquant 1.22.0 r-base (0/2) (2/2) (2/2) True False -map_peptides_to_bed 41.0 1.0 map_peptides_to_bed Map peptides to a reference genome for display by a genome browser To update Proteomics map_peptides_to_bed galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/map_peptides_to_bed 0.2 biopython 1.70 (0/1) (0/1) (1/1) True False -maxquant 5804.0 407.0 maxquant, maxquant_mqpar wrapper for MaxQuant Up-to-date https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/maxquant Proteomics maxquant galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/maxquant 2.0.3.0 maxquant 2.0.3.0 (2/2) (2/2) (2/2) True False -meta_proteome_analyzer 123.0 10.0 meta_proteome_analyzer MetaProteomeAnalyzer Up-to-date https://github.com/compomics/meta-proteome-analyzer/ Proteomics meta_proteome_analyzer galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/meta_proteome_analyzer 2.0.0 mpa-portable 2.0.0 (0/1) (0/1) (1/1) True False -metagene_annotator 636.0 115.0 metagene_annotator MetaGeneAnnotator gene-finding program for prokaryote and phage To update Sequence Analysis metagene_annotator galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/metagene_annotator 1.0.0 metagene_annotator 1.0 (0/1) (0/1) (1/1) True True -metanovo 4181.0 15.0 metanovo Produce targeted databases for mass spectrometry analysis. Up-to-date https://github.com/uct-cbio/proteomics-pipelines Proteomics metanovo galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/metanovo 1.9.4 metanovo 1.9.4 (0/1) (0/1) (1/1) True False -metaquantome metaquantome_db, metaquantome_expand, metaquantome_filter, metaquantome_sample, metaquantome_stat, metaquantome_viz quantitative analysis of microbiome taxonomy and function Up-to-date https://github.com/galaxyproteomics/metaquantome/ Proteomics metaquantome galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/metaquantome 2.0.2 metaquantome 2.0.2 (0/6) (6/6) (6/6) True False -moFF proteomics_moff moFF (a modest Feature Finder) extracts MS1 intensities from RAW and mzML spectrum files. Up-to-date https://github.com/compomics/moFF Proteomics proteomics_moff galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/moFF 2.0.3 moff 2.0.3 (0/1) (1/1) (1/1) True False -morpheus 140.0 4.0 morpheus Morpheus MS Search Application To update Proteomics morpheus galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/morpheus 2.255.0 morpheus 287 (0/1) (1/1) (1/1) True False -mqppep mqppep_anova, mqppep_preproc MaxQuant Phosphoproteomic Enrichment Pipeline - Preprocessing and ANOVA To update https://github.com/galaxyproteomics/tools-galaxyp/ Proteomics mqppep galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/mqppep 0.1.19 bioconductor-preprocesscore 1.64.0 (0/2) (0/2) (2/2) True False -msconvert 20406.0 190.0 msconvert msconvert Convert and/or filter mass spectrometry files (including vendor formats) using the official Docker container To update Proteomics msconvert galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msconvert 3.0.20287 (1/1) (1/1) (1/1) True False -msgfplus 507.0 5.0 msgfplus MSGF+ To update Proteomics msgfplus galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msgfplus 0.5 msgf_plus 2023.01.1202 (0/1) (0/1) (1/1) True False -msms_extractor 110.0 1.0 msms_extractor Extract MS/MS scans from the mzML file(s) based on PSM report. To update Proteomics msms_extractor galaxyp 1.0.0 proteowizard 3_0_9992 (0/1) (0/1) (1/1) True False -msstats 2036.0 144.0 msstats MSstats tool for analyzing mass spectrometry proteomic datasets To update https://github.com/MeenaChoi/MSstats Proteomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msstats 4.0.0 bioconductor-msstats 4.10.0 (1/1) (1/1) (1/1) True False -msstatstmt 726.0 71.0 msstatstmt MSstatsTMT protein significance analysis in shotgun mass spectrometry-based proteomic experiments with tandem mass tag (TMT) labeling To update http://msstats.org/msstatstmt/ Proteomics msstatstmt galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msstatstmt 2.0.0 bioconductor-msstatstmt 2.10.0 (0/1) (1/1) (1/1) True False -mt2mq 270.0 19.0 mt2mq Tool to prepare metatranscriptomic outputs from ASaiM for Metaquantome To update Proteomics mt2mq galaxyp 1.1.0 r-tidyverse (0/1) (0/1) (1/1) True False -mz_to_sqlite 844.0 33.0 mz_to_sqlite Creates a SQLite database for proteomics data To update Proteomics mz_to_sqlite galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/mz_to_sqlite 2.1.1+galaxy0 mztosqlite 2.1.1 (1/1) (1/1) (1/1) True False -openms AccurateMassSearch, AssayGeneratorMetabo, BaselineFilter, CVInspector, ClusterMassTraces, ClusterMassTracesByPrecursor, CometAdapter, CompNovo, CompNovoCID, ConsensusID, ConsensusMapNormalizer, CruxAdapter, DTAExtractor, DatabaseFilter, DatabaseSuitability, DeMeanderize, Decharger, DecoyDatabase, Digestor, DigestorMotif, EICExtractor, ERPairFinder, Epifany, ExternalCalibration, FFEval, FalseDiscoveryRate, FeatureFinderCentroided, FeatureFinderIdentification, FeatureFinderIsotopeWavelet, FeatureFinderMRM, FeatureFinderMetabo, FeatureFinderMetaboIdent, FeatureFinderMultiplex, FeatureLinkerLabeled, FeatureLinkerUnlabeled, FeatureLinkerUnlabeledKD, FeatureLinkerUnlabeledQT, FidoAdapter, FileConverter, FileFilter, FileInfo, FileMerger, FuzzyDiff, GNPSExport, HighResPrecursorMassCorrector, IDConflictResolver, IDExtractor, IDFileConverter, IDFilter, IDMapper, IDMassAccuracy, IDMerger, IDPosteriorErrorProbability, IDRTCalibration, IDRipper, IDScoreSwitcher, IDSplitter, InternalCalibration, IsobaricAnalyzer, LabeledEval, LuciphorAdapter, MRMMapper, MRMPairFinder, MRMTransitionGroupPicker, MSFraggerAdapter, MSGFPlusAdapter, MSSimulator, MSstatsConverter, MaRaClusterAdapter, MapAlignerIdentification, MapAlignerPoseClustering, MapAlignerSpectrum, MapAlignerTreeGuided, MapNormalizer, MapRTTransformer, MapStatistics, MascotAdapter, MascotAdapterOnline, MassCalculator, MassTraceExtractor, MetaProSIP, MetaboliteAdductDecharger, MetaboliteSpectralMatcher, MultiplexResolver, MyriMatchAdapter, MzMLSplitter, MzTabExporter, NoiseFilterGaussian, NoiseFilterSGolay, NovorAdapter, NucleicAcidSearchEngine, OMSSAAdapter, OpenMSDatabasesInfo, OpenPepXL, OpenPepXLLF, OpenSwathAnalyzer, OpenSwathAssayGenerator, OpenSwathChromatogramExtractor, OpenSwathConfidenceScoring, OpenSwathDIAPreScoring, OpenSwathDecoyGenerator, OpenSwathFeatureXMLToTSV, OpenSwathFileSplitter, OpenSwathMzMLFileCacher, OpenSwathRTNormalizer, OpenSwathRewriteToFeatureXML, OpenSwathWorkflow, PSMFeatureExtractor, PTModel, PeakPickerHiRes, PeakPickerIterative, PeakPickerWavelet, PepNovoAdapter, PeptideIndexer, PercolatorAdapter, PhosphoScoring, PrecursorIonSelector, PrecursorMassCorrector, ProteinInference, ProteinQuantifier, ProteinResolver, QCCalculator, QCEmbedder, QCExporter, QCExtractor, QCImporter, QCMerger, QCShrinker, QualityControl, RNADigestor, RNAMassCalculator, RNPxlSearch, RNPxlXICFilter, RTEvaluation, RTModel, SeedListGenerator, SemanticValidator, SequenceCoverageCalculator, SimpleSearchEngine, SiriusAdapter, SpecLibCreator, SpecLibSearcher, SpectraFilterBernNorm, SpectraFilterMarkerMower, SpectraFilterNLargest, SpectraFilterNormalizer, SpectraFilterParentPeakMower, SpectraFilterScaler, SpectraFilterSqrtMower, SpectraFilterThresholdMower, SpectraFilterWindowMower, SpectraMerger, SpectraSTSearchAdapter, StaticModification, SvmTheoreticalSpectrumGeneratorTrainer, TICCalculator, TOFCalibration, TargetedFileConverter, TextExporter, TransformationEvaluation, TriqlerConverter, XFDR, XMLValidator, XTandemAdapter OpenMS Suite for LC/MS data management and analyses To update https://www.openms.de/ Proteomics openms galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/openms 2.8 openms 3.1.0 (1/164) (35/164) (160/164) True False -pathwaymatcher reactome_pathwaymatcher Reactome Pathway Matcher To update https://github.com/LuisFranciscoHS/PathwayMatcher Proteomics reactome_pathwaymatcher galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pathwaymatcher pathwaymatcher 1.9.1 (0/1) (0/1) (1/1) True False -pep_pointer 498.0 9.0 pep_pointer PepPointer categorizes peptides by their genomic coordinates. To update Genomic Interval Operations, Proteomics pep_pointer galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pep_pointer 0.1.3+galaxy1 python (1/1) (1/1) (1/1) True False -pepquery 4862.0 23.0 pepquery A peptide-centric MS search engine for novel peptide identification and validation. To update https://pepquery.org Proteomics pepquery galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pepquery 1.6.2 pepquery 2.0.2 (0/1) (0/1) (1/1) True False -pepquery2 707.0 10.0 pepquery2, pepquery2_index, pepquery2_show_sets PepQuery2 peptide-centric MS search for peptide identification and validation Up-to-date https://pepquery.org Proteomics pepquery2 galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pepquery2 2.0.2 pepquery 2.0.2 (0/3) (0/3) (3/3) True False -peptide_genomic_coordinate 468.0 9.0 peptide_genomic_coordinate Gets genomic coordinate of peptides based on the information in mzsqlite and genomic mapping sqlite files To update Proteomics peptide_genomic_coordinate galaxyp 1.0.0 python (1/1) (1/1) (1/1) True False -peptideshaker 17477.0 485.0 fasta_cli, ident_params, peptide_shaker, search_gui PeptideShaker and SearchGUI To update http://compomics.github.io Proteomics peptideshaker galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/peptideshaker searchgui 4.3.6 (4/4) (4/4) (4/4) True False -pepxml_to_xls Convert PepXML to Tabular To update Proteomics pepxml_to_xls galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pepxml_to_xls (0/1) (0/1) (0/1) True False -percolator 368.0 5.0 batched_set_list_creator, percolator, percolator_input_converters, pout2mzid Percolator Up-to-date Proteomics percolator galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/percolator 3.5 percolator 3.5 (0/4) (4/4) (4/4) True False -pi_db_tools calc_delta_pi, pi_db_split, pi_dbspec_align HiRIEF tools To update Proteomics hirieftools galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/pi_db_tools 1.3 python (0/3) (0/3) (0/3) True False -pmd_fdr pmd_fdr Calculate Precursor Mass Discrepancy (PMD) for MS/MS To update https://github.com/slhubler/PMD-FDR-for-Galaxy-P Proteomics pmd_fdr galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pmd_fdr 1.4.0 r-base (0/1) (0/1) (0/1) True False -custom_pro_db 1652.0 57.0 custom_pro_db CustomProDB To update https://bioconductor.org/packages/release/bioc/html/customProDB.html Proteomics custom_pro_db galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/bumbershoot/custom_pro_db 1.22.0 bioconductor-rgalaxy 1.37.1 (1/1) (1/1) (1/1) True False -custom_pro_db_annotation_data_manager CustomProDB Annotation To update https://bioconductor.org/packages/release/bioc/html/customProDB.html Proteomics custom_pro_db_annotation_data_manager galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/bumbershoot/custom_pro_db (0/1) (0/1) (0/1) True False -psm2sam PSMtoSAM PSM to SAM To update https://bioconductor.org/packages/release/bioc/html/proBAMr.html Proteomics psm_to_sam galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/bumbershoot/psm2sam 1.3.2.1 r-base (0/1) (0/1) (0/1) True False -translate_bed 643.0 49.0 translate_bed Translate BED transcript CDS or cDNA in 3 frames To update http://rest.ensembl.org/ Proteomics translate_bed galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteogenomics/translate_bed 0.1.0 (1/1) (1/1) (1/1) True False -proteomiqon_joinquantpepionswithproteins 366.0 4.0 proteomiqon_joinquantpepionswithproteins The tool JoinQuantPepIonsWithProteins combines results from ProteinInference and PSMBasedQuantification. To update https://csbiology.github.io/ProteomIQon/tools/JoinQuantPepIonsWithProteins.html Proteomics proteomiqon_joinquantpepionswithproteins galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_joinquantpepionswithproteins 0.0.1 proteomiqon-joinquantpepionswithproteins 0.0.2 (0/1) (0/1) (1/1) True False -proteomiqon_labeledproteinquantification 14.0 5.0 proteomiqon_labeledproteinquantification The tool LabeledProteinQuantification estimates protein abundances using quantified peptide ions. To update https://csbiology.github.io/ProteomIQon/tools/LabeledProteinQuantification.html Proteomics proteomiqon_labeledproteinquantification galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_labeledproteinquantification 0.0.1 proteomiqon-labeledproteinquantification 0.0.3 (0/1) (0/1) (1/1) True False -proteomiqon_labelfreeproteinquantification 6.0 3.0 proteomiqon_labelfreeproteinquantification The tool LabelFreeProteinQuantification estimates protein abundances using quantified peptide ions. To update https://csbiology.github.io/ProteomIQon/tools/LabelfreeProteinQuantification.html Proteomics proteomiqon_labelfreeproteinquantification galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_labelfreeproteinquantification 0.0.1 proteomiqon-labelfreeproteinquantification 0.0.3 (0/1) (0/1) (1/1) True False -proteomiqon_mzmltomzlite 721.0 5.0 proteomiqon_mzmltomzlite The tool MzMLToMzLite allows to convert mzML files to mzLite files. Up-to-date https://csbiology.github.io/ProteomIQon/tools/MzMLToMzLite.html Proteomics proteomiqon_mzmltomzlite galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomIQon_MzMLToMzLite 0.0.8 proteomiqon-mzmltomzlite 0.0.8 (0/1) (0/1) (1/1) True False -proteomiqon_peptidedb 96.0 6.0 proteomiqon_peptidedb The tool ProteomIQon PeptideDB creates a peptide database in the SQLite format. Up-to-date https://csbiology.github.io/ProteomIQon/tools/PeptideDB.html Proteomics proteomiqon_peptidedb galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_peptidedb 0.0.7 proteomiqon-peptidedb 0.0.7 (0/1) (0/1) (1/1) True False -proteomiqon_peptidespectrummatching 686.0 4.0 proteomiqon_peptidespectrummatching Given raw an MS run in the mzLite format, this tool iterates across all MS/MS scans, determines precursor charge states and possible peptide spectrum matches using reimplementations of SEQUEST,Andromeda and XTandem. Up-to-date https://csbiology.github.io/ProteomIQon/tools/PeptideSpectrumMatching.html Proteomics proteomiqon_peptidespectrummatching galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_peptidespectrummatching 0.0.7 proteomiqon-peptidespectrummatching 0.0.7 (0/1) (0/1) (1/1) True False -proteomiqon_proteininference 89.0 4.0 proteomiqon_proteininference MS-based shotgun proteomics estimates protein abundances using a proxy: peptides. The process of 'Protein Inference' is concerned with the mapping of identified peptides to the proteins they putatively originated from. Up-to-date https://csbiology.github.io/ProteomIQon/tools/ProteinInference.html Proteomics proteomiqon_proteininference galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_proteininference 0.0.7 proteomiqon-proteininference 0.0.7 (0/1) (0/1) (1/1) True False -proteomiqon_psmbasedquantification 604.0 4.0 proteomiqon_psmbasedquantification The PSMBasedQuantification tool was designed to allow label-free quantification as well as quantification of full metabolic labeled samples. To update https://csbiology.github.io/ProteomIQon/tools/PSMBasedQuantification.html Proteomics proteomiqon_psmbasedquantification galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_psmbasedquantification 0.0.8 proteomiqon-psmbasedquantification 0.0.9 (0/1) (0/1) (1/1) True False -proteomiqon_psmstatistics 694.0 4.0 proteomiqon_psmstatistics The PSMStatistics tool utilizes semi supervised machine learning techniques to integrate search engine scores as well as the mentioned quality scores into one single consensus score. Up-to-date https://csbiology.github.io/ProteomIQon/tools/PSMStatistics.html Proteomics proteomiqon_psmstatistics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_psmstatistics 0.0.8 proteomiqon-psmstatistics 0.0.8 (0/1) (0/1) (1/1) True False -proteore_venn_diagram 15.0 proteore_venn_diagram ProteoRE JVenn Diagram To update Proteomics proteore_venn_diagram galaxyp 2021.06.08 python (0/1) (0/1) (0/1) True False -psm_validation 20.0 psmvalidator Validate PSM from Ion Fragmentation To update https://github.com/galaxyproteomics/psm_fragments.git Proteomics psm_validation galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/psm_validation 1.0.3 (0/1) (0/1) (1/1) True False -pyprophet pyprophet_export, pyprophet_merge, pyprophet_peptide, pyprophet_protein, pyprophet_score, pyprophet_subsample Semi-supervised learning and scoring of OpenSWATH results. To update https://github.com/PyProphet/pyprophet Proteomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pyprophet 2.1.4 pyprophet 2.2.5 (0/6) (4/6) (6/6) True False -pyteomics mztab2tsv Tools using the pyteomics library pyteomics Pyteomics Framework for proteomics data analysis, supporting mzML, MGF, pepXML and more. Protein identification Proteomics, Proteomics experiment To update https://pyteomics.readthedocs.io/en/latest/ Proteomics, Metabolomics pyteomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pyteomics 4.4.1 pyteomics 4.7.1 (0/1) (0/1) (1/1) True False -quantp 230.0 6.0 quantp Correlation between protein and transcript abundance To update Proteomics quantp galaxyp 1.1.2 r-data.table 1.11.6 (0/1) (0/1) (1/1) True False -quantwiz_iq 32.0 1.0 quantwiz_iq Isobaric Quantitation using QuantWiz-IQ Up-to-date https://sourceforge.net/projects/quantwiz/ Proteomics quantwiz_iq galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/quantwiz_iq 2.0 quantwiz-iq 2.0 (0/1) (0/1) (1/1) True False -rawtools 175.0 14.0 rawtools Raw Tools To update https://github.com/kevinkovalchik/RawTools Proteomics rawtools galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/rawtools rawtools 2.0.4 (0/1) (1/1) (1/1) True False -sixgill 293.0 24.0 sixgill_build, sixgill_filter, sixgill_makefasta, sixgill_merge Six-frame Genome-Inferred Libraries for LC-MS/MS Up-to-date Proteomics, MetaProteomics sixgill galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/sixgill 0.2.4 sixgill 0.2.4 (0/4) (0/4) (4/4) True False -spectrast2spectrast_irt gp_spectrast2spectrast_irt Filter from spectraST files to swath input files To update Proteomics spectrast2spectrast_irt galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/spectrast2spectrast_irt 0.1.0 msproteomicstools 0.11.0 (0/1) (0/1) (0/1) True False -spectrast2tsv gp_spectrast2tsv Filter from spectraST files to swath input files To update Proteomics spectrast2tsv galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/spectrast2tsv 0.1.0 msproteomicstools 0.11.0 (0/1) (0/1) (0/1) True False -translate_bed_sequences 57.0 6.0 translate_bed_sequences Perform 3 frame translation of BED file augmented with a sequence column To update Proteomics translate_bed_sequences galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/translate_bed_sequences 0.2.0 biopython 1.70 (0/1) (0/1) (1/1) True False -unipept 5005.0 115.0 unipept Unipept retrieves metaproteomics information To update https://github.com/galaxyproteomics/tools-galaxyp Proteomics unipept galaxyp https://unipept.ugent.be/apidocs 4.5.1 python (1/1) (1/1) (1/1) True False -uniprotxml_downloader 1360.0 79.0 uniprotxml_downloader Download UniProt proteome in XML or fasta format To update Proteomics uniprotxml_downloader galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/uniprotxml_downloader 2.4.0 requests (0/1) (1/1) (1/1) True False -validate_fasta_database 86.0 25.0 validate_fasta_database runs Compomics database identification tool on any FASTA database, and separates valid and invalid entries based on a series of checks. To update Fasta Manipulation, Proteomics validate_fasta_database galaxyp 0.1.5 validate-fasta-database 1.0 (0/1) (0/1) (1/1) True False -bamparse bamparse Generates hit count lists from bam alignments. To update http://artbio.fr RNA, Transcriptomics bamparse artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/bamparse 4.1.1 pysam 0.22.0 (0/1) (0/1) (0/1) True False -blast_to_scaffold blast2scaffold Generate DNA scaffold from blastn or tblastx alignments of Contigs To update http://artbio.fr RNA, Sequence Analysis, Assembly blast_to_scaffold artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/blast_to_scaffold 1.1.0 python (0/1) (0/1) (0/1) True False -blastparser_and_hits BlastParser_and_hits Parse blast outputs and compile hits To update http://artbio.fr Assembly, RNA blastparser_and_hits artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/blastparser_and_hits 2.7.1 python (0/1) (0/1) (0/1) True False -blastx_to_scaffold blastx2scaffold Generate DNA scaffold from blastx alignment of Contigs To update http://artbio.fr RNA, Sequence Analysis, Assembly blastx_to_scaffold artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/blastx_to_scaffold 1.1.1 python (0/1) (0/1) (0/1) True False -cap3 7766.0 101.0 cap3 cap3 wrapper To update http://artbio.fr Assembly cap3 artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/cap3 2.0.1 cap3 10.2011 (0/1) (1/1) (1/1) True False -deseq2_normalization deseq2_normalization Normalizes gene hitlists To update http://artbio.fr RNA, Transcriptomics, Sequence Analysis, Statistics deseq2_normalization artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/deseq2_normalization 1.40.2+galaxy0 bioconductor-deseq2 1.42.0 (0/1) (0/1) (0/1) True False -ez_histograms ez_histograms ggplot2 histograms and density plots To update https://github.com/tidyverse/ggplot2 Visualization, Statistics ez_histograms artbio https://github.com/artbio/tools-artbio/tree/main/tools/ez_histograms 3.4.4 r-ggplot2 2.2.1 (0/1) (0/1) (0/1) False -fisher_test fishertest Fisher's exact test on two-column hit lists. To update http://artbio.fr RNA, Statistics fishertest artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/fisher_test 2.32.0+galaxy0 bioconductor-qvalue 2.34.0 (0/1) (0/1) (0/1) True False -gsc_high_dimensions_visualisation high_dimensions_visualisation Generates PCA, t-SNE and HCPC visualisation To update http://artbio.fr Transcriptomics, Visualization gsc_high_dimensions_visualisation artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/gsc_high_dimension_visualization 4.3+galaxy0 r-optparse 1.3.2 (0/1) (0/1) (0/1) True False -guppy guppy-basecaller A wrapper for the guppy basecaller tool from Oxford Nanopore Technologies To update http://artbio.fr Nanopore guppy_basecaller artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/guppy 0.2.2 (0/1) (0/1) (0/1) True False -high_dim_heatmap high_dim_heatmap gplot heatmap.2 function adapted for plotting large heatmaps To update https://github.com/cran/gplots Visualization high_dim_heatmap artbio https://github.com/artbio/tools-artbio/tree/main/tools/high_dim_heatmap 3.1.3+galaxy0 r-gplots 2.17.0 (0/1) (0/1) (0/1) True False -mapping_quality_stats mapqstatistics Collects and shows the distribution of MAPQ values in a BAM alignment file To update http://artbio.fr Sequence Analysis, Statistics mapping_quality_stats artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/mapping_quality_stats 0.22.0 r-optparse 1.3.2 (0/1) (0/1) (0/1) True False -mircounts mircounts Generates miRNA count lists from read alignments to mirBase. To update http://artbio.fr RNA, Transcriptomics mircounts artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/mircounts 1.6 tar (0/1) (1/1) (0/1) True False -oases oasesoptimiserv Short read assembler To update http://artbio.fr Assembly, RNA oases artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/oases 1.4.0 oases 0.2.09 (0/1) (0/1) (0/1) True False -probecoverage probecoverage computes and plots read coverage of genomic regions by sequencing datasets Up-to-date http://artbio.fr Sequence Analysis, Genomic Interval Operations, Graphics, Statistics probecoverage artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/probecoverage 0.22.0 pysam 0.22.0 (0/1) (0/1) (0/1) True False -rsem 2273.0 199.0 extract_transcript_to_gene_map_from_trinity, purgegtffrommultichromgenes, rsembowtie2, rsembowtie transcript quantification from RNA-Seq data To update https://github.com/deweylab/RSEM Transcriptomics, RNA rsem artbio https://github.com/artbio/tools-artbio/tree/master/tools/rsem rsem 1.3.3 (0/4) (0/4) (1/4) True False -sashimi_plot sashimi_plot Generates a sashimi plot from bam files. To update http://artbio.fr RNA, Transcriptomics, Graphics, Visualization sashimi_plot artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/sashimi_plot 0.1.1 python (0/1) (0/1) (0/1) True False -small_rna_clusters small_rna_clusters clusters small rna reads in alignment BAM files To update http://artbio.fr RNA, SAM, Graphics, Next Gen Mappers small_rna_clusters artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/small_rna_clusters 1.3.0 pysam 0.22.0 (0/1) (0/1) (0/1) True False -small_rna_maps small_rna_maps Generates small read maps from alignment BAM files To update http://artbio.fr RNA, SAM, Graphics, Next Gen Mappers small_rna_maps artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/small_rna_maps 3.1.1 numpy (0/1) (0/1) (0/1) True False -small_rna_signatures overlapping_reads, signature Computes the tendency of small RNAs to overlap with each other. To update http://artbio.fr RNA small_rna_signatures artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/small_rna_signatures 3.4.2 pysam 0.22.0 (0/2) (0/2) (0/2) True False -sr_bowtie bowtieForSmallRNA bowtie wrapper tool to align small RNA sequencing reads To update http://artbio.fr RNA, Next Gen Mappers sr_bowtie artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/sr_bowtie 2.3.0 bowtie 1.3.1 (0/1) (0/1) (0/1) True False -sr_bowtie_dataset_annotation sr_bowtie_dataset_annotation Maps iteratively small RNA sequencing datasets to reference sequences. To update http://artbio.fr RNA sr_bowtie_dataset_annotation artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/sr_bowtie_dataset_annotation 2.8 bowtie 1.3.1 (0/1) (0/1) (0/1) True False -tarfast5 tarfast5 produces a tar.gz archive of fast5 sequence files To update http://artbio.fr Nanopore tarfast5 artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/tarfast5 0.6.1 pigz (0/1) (0/1) (0/1) True False -xpore xpore_dataprep, xpore_diffmod Identification and quantification of differential RNA modifications from direct RNA sequencing To update https://github.com/GoekeLab/xpore Nanopore xpore artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/xpore 2.1+galaxy0 xpore 2.1 (0/2) (0/2) (0/2) True False -yac_clipper yac Clips 3' adapters for small RNA sequencing reads. To update http://artbio.fr RNA, Fastq Manipulation yac_clipper artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/yac_clipper 2.5.1 python (0/1) (0/1) (0/1) True False -EMLassemblyline eal_table_template, eal_templates, eml2eal, entities_template, geo_cov_template, makeeml, raster_template, taxo_cov_template, vector_template Tools using EML Assembly Line R package to generate EML metadata from template metadata files and vice versa To update https://github.com/EDIorg/EMLassemblyline Ecology emlassemblyline ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/EMLassemblyline 0.1.1+galaxy0 r-emlassemblyline (0/9) (0/9) (9/9) True False -Ecoregionalization_workflow ecoregion_brt_analysis, ecoregion_cluster_estimate, ecoregion_clara_cluster, ecoregion_eco_map, ecoregion_taxa_seeker Tools to compute ecoregionalization with BRT model predictions and clustering. To update https://github.com/PaulineSGN/Workflow_Galaxy Ecology ecoregionalization ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/Ecoregionalization_workflow 0.1.0+galaxy0 r-base (0/5) (0/5) (5/5) True False -Geom_mean_workflow Map_shp, Mean_geom, bar_plot Tools to compute The evolution of the total volume of very large trees, standing dead wood and dead wood on the ground on an area and the rate of devolution of the volume of wood favorable to biodiversity by large ecological regions (France). To update https://github.com/PaulineSGN/Galaxy_tool_moyenne_geom Ecology Geometric means (Dead wood) ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/Geom_mean_workflow 0.1.0+galaxy0 r-base (0/3) (0/3) (3/3) False -PAMPA pampa_communitymetrics, pampa_presabs, pampa_glmcomm, pampa_glmsp, pampa_plotglm Tools to compute and analyse biodiversity metrics To update Ecology pampa ecology https://github.com/ColineRoyaux/PAMPA-Galaxy 0.0.2 (0/5) (5/5) (5/5) True True -champ_blocs cb_dissim, cb_ivr, cb_div Compute indicators for turnover boulders fields To update Ecology ecology https://github.com/Marie59/champ_blocs 0.0.0 r-base (0/3) (0/3) (3/3) True False -consensus_from_alignments aligned_to_consensus Tool to compute a consensus sequence from several aligned fasta sequences To update Sequence Analysis consalign ecology https://github.com/ColineRoyaux/Galaxy_tool_projects/tree/main/consensus_from_alignments 1.0.0 r-bioseq (0/1) (0/1) (1/1) True False -data_exploration tool_anonymization, ecology_homogeneity_normality, ecology_beta_diversity, ecology_link_between_var, ecology_presence_abs_abund, ecology_stat_presence_abs Explore data through multiple statistical tools To update Ecology ecology https://github.com/Marie59/Data_explo_tools 0.0.0 r-tangles (0/6) (0/6) (6/6) True False -xarray timeseries_extraction, xarray_coords_info, xarray_mapplot, xarray_metadata_info, xarray_netcdf2netcdf, xarray_select xarray (formerly xray) is an open source project and Python package that makes working withlabelled multi-dimensional arrays simple, efficient, and fun!xarray integrates with Dask to support parallel computations and streaming computation on datasetsthat don’t fit into memory. To update http://xarray.pydata.org Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/data_manipulation/xarray/ 2022.3.0 xarray (5/6) (2/6) (6/6) True False -gdal gdal_gdal_merge, gdal_gdal_translate, gdal_gdaladdo, gdal_gdalbuildvrt, gdal_gdalinfo, gdal_gdalwarp, gdal_ogr2ogr, gdal_ogrinfo Geospatial Data Abstraction Library tools are all dedicated to manipulate raster and vector geospatial data formats. To update https://www.gdal.org Ecology gdal ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/gdal 3.0.0 (0/8) (0/8) (8/8) True False -interpolation interpolation_run_idw_interpolation Run IDW interpolation based on a .csv and .geojson file To update https://github.com/AquaINFRA/galaxy Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/interpolation 1.0 r-getopt (0/1) (0/1) (1/1) False -medenv iabiodiv_smartbiodiv_med_environ Retrieve environmental data from etopo, cmems and woa To update https://github.com/jeremyfix/medenv Ecology, Data Source ecology https://github.com/jeremyfix/medenv 0.0.1 pandas (0/1) (0/1) (1/1) False -obisindicators 45.0 4.0 obisindicators, obis_data Compute biodiveristy indicators for marine data from obis To update https://github.com/Marie59/obisindicators Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/obisindicators 0.0.2 r-base (1/2) (0/2) (2/2) True True -ocean argo_getdata Access, process, visualise oceanographic data for the Earth System To update https://github.com/Marie59/FE-ft-ESG/tree/main/argo Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/ocean 0.1.15 (0/1) (0/1) (1/1) False -regionalgam regionalgam_ab_index, regionalgam_autocor_acf, regionalgam_flight_curve, regionalgam_glmmpql, regionalgam_gls_adjusted, regionalgam_gls, regionalgam_plot_trend To update https://github.com/RetoSchmucki/regionalGAM Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/regionalgam 1.5 r-mgcv (0/7) (0/7) (7/7) True False -spocc spocc_occ Get species occurences data To update https://cran.r-project.org/web/packages/spocc/index.html Ecology spocc_occ ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/spocc 1.2.2 (0/1) (0/1) (1/1) True False -srs_tools srs_diversity_maps, srs_global_indices, srs_process_data, srs_spectral_indices, srs_pca, srs_preprocess_s2, srs_metadata Compute biodiversity indicators for remote sensing data from Sentinel 2 To update Ecology ecology https://github.com/Marie59/Sentinel_2A/srs_tools 0.0.1 r-base (4/7) (0/7) (7/7) True False -stoc stoceps_filteringsp, stoceps_glm, stoceps_glm_group, stoceps_maketablecarrer, stoceps_trend_indic Tools to analyse STOC data. To update Ecology stoceps ecology https://github.com/Alanamosse/Galaxy-E/tree/stoctool/tools/stoc 0.0.2 (0/5) (0/5) (5/5) True False -vigiechiro vigiechiro_bilanenrichipf, vigiechiro_bilanenrichirp, vigiechiro_idcorrect_2ndlayer, vigiechiro_idvalid Tools created by the vigiechiro team to analyses and identify chiro sounds files. To update https://www.vigienature-ecole.fr/les-observatoires/le-protocole-vigie-chiro Ecology vigiechiro ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/vigiechiro 0.1.1 (0/4) (0/4) (4/4) True False -climate-stripes climate_stripes Create climate stripes from a tabular input file To update https://www.climate-lab-book.ac.uk/2018/warming-stripes/ Climate Analysis, Visualization climate_stripes climate https://github.com/NordicESMhub/galaxy-tools/tree/master/tools/climate-stripes 1.0.2 python (1/1) (1/1) (1/1) True False -mean-per-zone mean_per_zone Creates a png image showing statistic over areas as defined in the vector file To update https://github.com/NordicESMhub/galaxy-tools/blob/master/tools/mean-per-zone/ Visualization, GIS, Climate Analysis mean_per_zone climate https://github.com/NordicESMhub/galaxy-tools/tree/master/tools/mean-per-zone 0.2.0 python (0/1) (0/1) (1/1) True False -psy-maps psy_maps Visualization of regular geographical data on a map with psyplot To update https://github.com/Chilipp/psy-maps Visualization, Climate Analysis psy_maps climate https://github.com/NordicESMhub/galaxy-tools/tree/master/tools/psy-maps 1.2.1 python (0/1) (0/1) (1/1) True False -droplet-barcode-plot _dropletBarcodePlot Make a cell barcode plot for droplet single-cell RNA-seq QC To update https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary Sequence Analysis droplet_barcode_plot ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/droplet-rank-plot/.shed.yml 1.6.1+galaxy2 scxa-plots 0.0.1 (1/1) (0/1) (1/1) True False -fastq_provider fastq_provider Retrieval and download of FASTQ files from ENA and other repositories such as HCA. To update https://github.com/ebi-gene-expression-group/atlas-fastq-provider Data Source, RNA, Transcriptomics atlas_fastq_provider ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/fastq_provider 0.4.4 atlas-fastq-provider 0.4.7 (0/1) (0/1) (0/1) True False -gtf-2-gene-list _ensembl_gtf2gene_list Utility to extract annotations from Ensembl GTF files. To update https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary Sequence Analysis gtf2gene_list ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/gtf-2-gene-list/.shed.yml 1.52.0+galaxy0 atlas-gene-annotation-manipulation 1.1.0 (1/1) (1/1) (1/1) True False -fastq_utils fastq_filter_n, fastq_trim_poly_at Set of tools for handling fastq files To update https://github.com/nunofonseca/fastq_utils Transcriptomics, RNA fastq_utils ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/qc/fastq_utils 0.25.1+galaxy0 fastq_utils 0.25.2 (0/2) (0/2) (0/2) True False -salmon-kallisto-mtx-to-10x _salmon_kallisto_mtx_to_10x Transforms .mtx matrix and associated labels into a format compatible with tools expecting old-style 10X data To update https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary Sequence Analysis salmon_kallisto_mtx_to_10x ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/salmon-kallisto-mtx-to-10x/.shed.yml 0.0.1+galaxy6 scipy (1/1) (1/1) (1/1) True False -cell-types-analysis ct_build_cell_ontology_dict, ct_check_labels, ct_combine_tool_outputs, ct_downsample_cells, ct_get_consensus_outputs, ct_get_empirical_dist, ct_get_tool_perf_table, ct_get_tool_pvals Tools for analysis of predictions from scRNAseq cell type classification tools, see https://github.com/ebi-gene-expression-group/cell-types-analysis To update Transcriptomics, RNA, Statistics suite_cell_types_analysis ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.1.1 cell-types-analysis 0.1.11 (0/8) (0/8) (6/8) True False -data-hca hca_matrix_downloader Tools for interacting with the Human Cell Atlas resource https://prod.data.humancellatlas.org/explore/projects To update Transcriptomics, Sequence Analysis suite_human_cell_atlas_tools ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ v0.0.4+galaxy0 hca-matrix-downloader 0.0.4 (0/1) (0/1) (1/1) True False -data-scxa retrieve_scxa Tools for interacting with the EMBL-EBI Expression Atlas resource https://www.ebi.ac.uk/gxa/home https://www.ebi.ac.uk/gxa/sc/home To update Transcriptomics, Sequence Analysis suite_ebi_expression_atlas ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ v0.0.2+galaxy2 wget (1/1) (1/1) (1/1) True False -dropletutils 3934.0 126.0 dropletutils_empty_drops, dropletutils_read_10x De-composed DropletUtils functionality tools, based on https://github.com/ebi-gene-expression-group/dropletutils-scripts and DropletUtils 1.0.3 To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_dropletutils ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.0.4 dropletutils-scripts 0.0.5 (2/2) (0/2) (2/2) True False -garnett garnett_check_markers, garnett_classify_cells, garnett_get_feature_genes, garnett_get_std_output, garnett_train_classifier, garnett_transform_markers, update_marker_file De-composed Garnett functionality tools, see https://github.com/ebi-gene-expression-group/garnett-cli and r-garnett 0.2.8 To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_garnett ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 0.2.8 garnett-cli 0.0.5 (0/7) (0/7) (7/7) True False -monocle3 monocle3_create, monocle3_diffExp, monocle3_learnGraph, monocle3_orderCells, monocle3_partition, monocle3_plotCells, monocle3_preprocess, monocle3_reduceDim, monocle3_topmarkers De-composed monocle3 functionality tools, based on https://github.com/ebi-gene-expression-group/monocle-scripts and monocle3 0.1.2. To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_monocle3 ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 0.1.4 monocle3-cli 0.0.9 (9/9) (0/9) (9/9) True False -sc3 sc3_calc_biology, sc3_calc_consens, sc3_calc_dists, sc3_calc_transfs, sc3_estimate_k, sc3_kmeans, sc3_prepare De-composed SC3 functionality tools, based on https://github.com/ebi-gene-expression-group/bioconductor-sc3-scripts and SC3 1.8.0. To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_sc3 ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.8.0 sc3-scripts 0.0.6 (0/7) (0/7) (7/7) True False -scanpy anndata_ops, scanpy_filter_cells, scanpy_filter_genes, scanpy_find_cluster, scanpy_find_markers, scanpy_find_variable_genes, scanpy_integrate_bbknn, scanpy_integrate_combat, scanpy_integrate_harmony, scanpy_integrate_mnn, scanpy_plot_scrublet, scanpy_multiplet_scrublet, scanpy_compute_graph, scanpy_normalise_data, scanpy_parameter_iterator, scanpy_plot_embed, scanpy_plot_trajectory, scanpy_read_10x, scanpy_regress_variable, scanpy_run_diffmap, scanpy_run_dpt, scanpy_run_fdg, scanpy_run_paga, scanpy_run_pca, scanpy_run_tsne, scanpy_run_umap, scanpy_scale_data scanpy-scripts, command-line wrapper scripts around Scanpy. To update https://scanpy.readthedocs.io Transcriptomics, Sequence Analysis, RNA scanpy_scripts ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/tertiary-analysis/scanpy 1.9.3 scanpy-scripts 1.9.301 (17/27) (27/27) (27/27) True False -scater scater_calculate_cpm, scater_calculate_qc_metrics, scater_filter, scater_is_outlier, scater_normalize, scater_read_10x_results De-composed Scater functionality tools, based on https://github.com/ebi-gene-expression-group/bioconductor-scater-scripts and Scater 1.8.4. To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_scater ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.10.0 scater-scripts 0.0.5 (0/6) (1/6) (6/6) True False -scmap scmap_get_std_output, scmap_index_cell, scmap_index_cluster, scmap_preprocess_sce, scmap_scmap_cell, scmap_scmap_cluster, scmap_select_features De-composed scmap functionality tools, based on https://github.com/ebi-gene-expression-group/scmap-cli and scmap 1.6.0. To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_scmap ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.6.3 scmap-cli 0.1.0 (0/7) (0/7) (7/7) True False -scpred scpred_get_feature_space, scpred_get_std_output, scpred_predict_labels, scpred_train_model De-composed scPred functionality tools, see https://github.com/ebi-gene-expression-group/scpred-cli and r-scPred 1.0 To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_scpred ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.0.2 scpred-cli 0.1.0 (0/4) (0/4) (4/4) True False -seurat 1543.0 66.0 seurat_convert, seurat_dim_plot, seurat_export_cellbrowser, seurat_filter_cells, seurat_find_clusters, seurat_find_markers, seurat_find_neighbours, seurat_find_variable_genes, seurat_normalise_data, seurat_read10x, seurat_run_pca, seurat_run_tsne, seurat_scale_data De-composed Seurat functionality tools, based on https://github.com/ebi-gene-expression-group/r-seurat-scripts and Seurat 2.3.1 To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_seurat ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 0.3.0 seurat-scripts 4.0.0 (0/13) (0/13) (12/13) True False -mzml_validator mzml_validator mzML Validator checks if mzML file validates against XML Schema Definition of HUPO Proteomics Standard Initiative. To update https://github.com/RECETOX/galaxytools Metabolomics, Proteomics recetox https://github.com/RECETOX/galaxytools/tree/master/tools/mzml_validator 0.1.0+galaxy2 lxml (0/1) (0/1) (0/1) True False -consolidate_vcfs consolidate_vcfs Combines freebayes and mpileup files for use by vcf2snvalignment Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis consolidate_vcfs nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False -filter_density filterdensity Filter out position based on distance between SNVs Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis filter_density nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False -filter_stats filterstat SNVPhyl filter_stats Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis filter_stats nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False -filter_vcf filtervcf SNVPhyl filter_vcf Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis filter_vcf nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False -find_repeats findrepeat Find repetitive regions on a reference genome using MUMMer Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis find_repeats nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False -snv_matrix snvmatrix Generate matrix of SNV distances Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis snv_matrix nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False -vcf2snvalignment vcf2snvalignment Generates multiple alignment of variant calls Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis vcf2snvalignment nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False -verify_map verify_map Checks the mapping quality of all BAM(s) Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis verify_map nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False -suite_snvphyl SNVPhyl suite defining all dependencies for SNVPhyl To update Sequence Analysis suite_snvphyl_1_2_3 nml https://github.com/phac-nml/snvphyl-galaxy (0/1) (0/1) (0/1) True False -blast2go 1232.0 101.0 blast2go Maps BLAST results to GO annotation terms To update https://github.com/peterjc/galaxy_blast/tree/master/tools/blast2go Ontology Manipulation, Sequence Analysis blast2go peterjc https://github.com/peterjc/galaxy_blast/tree/master/tools/blast2go 0.0.11 b2g4pipe (0/1) (0/1) (0/1) False -blast_rbh 22499.0 121.0 blast_reciprocal_best_hits BLAST Reciprocal Best Hits (RBH) from two FASTA files To update https://github.com/peterjc/galaxy_blast/tree/master/tools/blast_rbh Fasta Manipulation, Sequence Analysis blast_rbh peterjc https://github.com/peterjc/galaxy_blast/tree/master/tools/blast_rbh 0.3.0 biopython 1.70 (0/1) (0/1) (1/1) False -blastxml_to_top_descr 264558.0 159.0 blastxml_to_top_descr Make table of top BLAST match descriptions To update https://github.com/peterjc/galaxy_blast/tree/master/tools/blastxml_to_top_descr Convert Formats, Sequence Analysis, Text Manipulation blastxml_to_top_descr peterjc https://github.com/peterjc/galaxy_blast/tree/master/tools/blastxml_to_top_descr 0.1.2 python (0/1) (0/1) (1/1) False -make_nr make_nr Make a FASTA file non-redundant To update https://github.com/peterjc/galaxy_blast/tree/master/tools/make_nr Fasta Manipulation, Sequence Analysis make_nr peterjc https://github.com/peterjc/galaxy_blast/tree/master/tools/make_nr 0.0.2 biopython 1.70 (0/1) (0/1) (0/1) False -ncbi_blast_plus 365597.0 4066.0 blastxml_to_tabular, get_species_taxids, ncbi_blastdbcmd_info, ncbi_blastdbcmd_wrapper, ncbi_blastn_wrapper, ncbi_blastp_wrapper, ncbi_blastx_wrapper, ncbi_convert2blastmask_wrapper, ncbi_deltablast_wrapper, ncbi_dustmasker_wrapper, ncbi_makeblastdb, ncbi_makeprofiledb, ncbi_psiblast_wrapper, ncbi_rpsblast_wrapper, ncbi_rpstblastn_wrapper, ncbi_segmasker_wrapper, ncbi_tblastn_wrapper, ncbi_tblastx_wrapper NCBI BLAST+ To update https://blast.ncbi.nlm.nih.gov/ Sequence Analysis ncbi_blast_plus devteam https://github.com/peterjc/galaxy_blast/tree/master/tools/ncbi_blast_plus 2.14.1 python (16/18) (16/18) (16/18) False +phyloseq phyloseq_from_dada2, phyloseq_plot_ordination, phyloseq_plot_richness Handling and analysis of high-throughput microbiome census data phyloseq phyloseq Provides a set of classes and tools to facilitate the import, storage, analysis, and graphical display of microbiome census data. Deposition, Analysis, Visualisation Microbiology, Sequence analysis, Metagenomics To update https://www.bioconductor.org/packages/release/bioc/html/phyloseq.html Metagenomics phyloseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/phyloseq 1.38.0 bioconductor-phyloseq 1.46.0 (0/3) (0/3) (3/3) True True +phyml 1770.0 104.0 phyml PhyML is a phylogeny software based on the maximum-likelihood principle. phyml PhyML Phylogenetic estimation software using Maximum Likelihood Phylogenetic tree generation (maximum likelihood and Bayesian methods) Phylogenetics, Bioinformatics, Phylogenetics Up-to-date http://www.atgc-montpellier.fr/phyml/ Phylogenetics phyml iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/phyml 3.3.20220408 phyml 3.3.20220408 (0/1) (1/1) (1/1) True True +picrust picrust_categorize, picrust_compare_biom, picrust_format_tree_and_trait_table, picrust_metagenome_contributions, picrust_normalize_by_copy_number, picrust_predict_metagenomes PICRUSt wrappers picrust PICRUSt PICRUSt (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) is a bioinformatics software package designed to predict metagenome functional content from marker gene (e.g., 16S rRNA) surveys and full genomes. Phylogenetic reconstruction, Expression analysis, Genome annotation, DNA barcoding Metagenomics, Microbial ecology, Functional, regulatory and non-coding RNA, Metagenomic sequencing To update https://picrust.github.io/picrust/ Metagenomics picrust iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/picrust 1.1.1 picrust 1.1.4 (0/6) (6/6) (5/6) True True +picrust2 picrust2_add_descriptions, picrust2_hsp, picrust2_metagenome_pipeline, picrust2_pathway_pipeline, picrust2_pipeline, picrust2_place_seqs, picrust2_shuffle_predictions PICRUSt2: Phylogenetic Investigation of Communities by Reconstruction of Unobserved States picrust2 PICRUSt2 PICRUSt2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) is a software for predicting functional abundances based only on marker gene sequences. Phylogenetic reconstruction, Expression analysis, Rarefaction, Pathway analysis Metagenomics, Microbiology, Phylogenetics, Metagenomic sequencing To update https://github.com/picrust/picrust2/wiki Metagenomics picrust2 iuc https://github.com/picrust/picrust2 2.5.1 picrust2 2.5.2 (0/7) (7/7) (7/7) True True +plasflow 22589.0 278.0 PlasFlow PlasFlow - Prediction of plasmid sequences in metagenomic contigs. Up-to-date https://github.com/smaegol/PlasFlow Sequence Analysis plasflow iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/plasflow 1.1.0 plasflow 1.1.0 (1/1) (1/1) (1/1) True True +plasmidfinder 22.0 8.0 plasmidfinder """PlasmidFinder provides the detection of replicons in the WGSand assigns the plasmids under study to lineages that trace backthe information to the existing knowledge on Inc groups and suggestspossible reference plasmids for each lineage""" PlasmidFinder PlasmidFinder PlasmidFinder is a tool for the identification and typing of Plasmid Replicons in Whole-Genome Sequencing (WGS). Genome assembly, Scaffolding, Multilocus sequence typing Whole genome sequencing, Sequence assembly, Mapping, Probes and primers Up-to-date https://bitbucket.org/genomicepidemiology/plasmidfinder/src/master/ Sequence Analysis plasmidfinder iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/plasmidfinder 2.1.6 plasmidfinder 2.1.6 (0/1) (0/1) (1/1) True True +polypolish 239.0 24.0 polypolish """Polypolish is a tool for polishing genome assemblies with short reads.Polypolish uses SAM files where each read has been aligned to all possible locations (not just a single best location).This allows it to repair errors in repeat regions that other alignment-based polishers cannot fix.""" Polypolish Polypolish Polypolish is a tool for polishing genome assemblies with short reads. Unlike other tools in this category, Polypolish uses SAM files where each read has been aligned to all possible locations (not just a single best location). This allows it to repair errors in repeat regions that other alignment-based polishers cannot fix. Genome assembly, Read mapping, Mapping assembly, Sequencing error detection Sequence assembly, Sequence composition, complexity and repeats, Mapping To update https://github.com/rrwick/Polypolish Sequence Analysis polypolish iuc https://github.com/mesocentre-clermont-auvergne/galaxy-tools/tree/master/tools/polypolish 0.5.0 polypolish 0.6.0 (0/1) (0/1) (1/1) True False +presto presto_alignsets, presto_assemblepairs, presto_buildconsensus, presto_collapseseq, presto_filterseq, presto_maskprimers, presto_pairseq, presto_parseheaders, presto_parselog, presto_partition, prestor_abseq3 pRESTO toolkit for immune repertoire analysis. presto pRESTO Integrated collection of platform-independent Python modules for processing raw reads from high-throughput (next-generation) sequencing of lymphocyte repertoires. Nucleic acid sequence analysis Sequencing, DNA, Immunology To update https://presto.readthedocs.io/ Sequence Analysis presto iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/presto 0.6.2 presto 0.7.2 (11/11) (0/11) (0/11) True False +pretext pretext_graph, pretext_map, pretext_snapshot Process genome contacts maps processing images. Up-to-date https://github.com/wtsi-hpag/PretextSnapshot Sequence Analysis suite_pretext iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pretext 0.0.6 pretextgraph 0.0.6 (2/3) (2/3) (3/3) True False +prinseq 7881.0 70.0 prinseq PRINSEQ is a tool for easy and rapid quality control and data processing of metagenomic and metatranscriptomic datasets prinseq PRINSEQ PRINSEQ is a sequence processing tool that can be used to filter, reformat and trim genomic and metagenomic sequence data. It generates summary statistics of the input in graphical and tabular formats that can be used for quality control steps. PRINSEQ is available as both standalone and web-based versions. Read pre-processing, Sequence trimming, Sequence contamination filtering Transcriptomics, Metagenomics, Genomics To update http://prinseq.sourceforge.net/manual.html Fastq Manipulation, Metagenomics prinseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/prinseq/ @TOOL_VERSION+galaxy2 prinseq 0.20.4 (1/1) (0/1) (1/1) True False +progressivemauve 1734.0 286.0 progressivemauve, xmfa2gff3 Mauve/ProgressiveMauve Multiple Sequence Aligner To update Sequence Analysis progressivemauve iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/progressivemauve progressivemauve snapshot_2015_02_13 (2/2) (0/2) (2/2) True False +prokka 371445.0 3233.0 prokka Rapid annotation of prokaryotic genomes prokka Prokka Software tool to annotate bacterial, archaeal and viral genomes quickly and produce standards-compliant output files. Gene prediction, Coding region prediction, Genome annotation Genomics, Model organisms, Virology Up-to-date http://github.com/tseemann/prokka Sequence Analysis prokka crs4 https://github.com/galaxyproject/tools-iuc/tree/master/tools/prokka/ 1.14.6 prokka 1.14.6 (1/1) (1/1) (1/1) True True +prot-scriber prot_scriber Protein annotation of short human readable descriptions To update https://github.com/usadellab/prot-scriber Proteomics prot_scriber iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/prot-scriber 0.1.4 prot-scriber 0.1.5 (0/1) (0/1) (1/1) True False +proteinortho 2092.0 125.0 proteinortho, proteinortho_grab_proteins, proteinortho_summary Proteinortho is a tool to detect orthologous proteins/genes within different species. proteinortho Proteinortho Proteinortho is a tool to detect orthologous genes within different species Homology-based gene prediction Phylogeny Up-to-date https://gitlab.com/paulklemm_PHD/proteinortho Proteomics proteinortho iuc https://gitlab.com/paulklemm_PHD/proteinortho 6.3.1 proteinortho 6.3.1 (0/3) (0/3) (3/3) True True +pureclip 1423.0 36.0 pureclip PureCLIP is an HMM based peak caller specifically designed for eCLIP/iCLIP data To update https://github.com/skrakau/PureCLIP Sequence Analysis, RNA, CLIP-seq pureclip iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pureclip 1.0.4 pureclip 1.3.1 (0/1) (0/1) (1/1) True False +purge_dups 16800.0 167.0 purge_dups Purge haplotigs and overlaps in an assembly based on read depth purge_dups purge_dups Identifying and removing haplotypic duplication in primary genome assemblies | haplotypic duplication identification tool | scripts/pd_config.py: script to generate a configuration file used by run_purge_dups.py | purge haplotigs and overlaps in an assembly based on read depth | Given a primary assembly pri_asm and an alternative assembly hap_asm (optional, if you have one), follow the steps shown below to build your own purge_dups pipeline, steps with same number can be run simultaneously. Among all the steps, although step 4 is optional, we highly recommend our users to do so, because assemblers may produce overrepresented seqeuences. In such a case, The final step 4 can be applied to remove those seqeuences Genome assembly, Read binning, Scaffolding Sequence assembly Up-to-date https://github.com/dfguan/purge_dups Assembly purge_dups iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/purge_dups 1.2.6 purge_dups 1.2.6 (1/1) (1/1) (1/1) True False +pycoqc 21123.0 350.0 pycoqc QC metrics for ONT Basecalling Up-to-date https://github.com/tleonardi/pycoQC Nanopore pycoqc iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pycoqc 2.5.2 pycoqc 2.5.2 (1/1) (1/1) (1/1) True True +pygenometracks 11332.0 377.0 pygenomeTracks pyGenomeTracks: Standalone program and library to plot beautiful genome browser tracks. Up-to-date https://github.com/deeptools/pyGenomeTracks Visualization pygenometracks iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pygenometracks 3.8 pygenometracks 3.8 (1/1) (1/1) (1/1) True True +pysradb pysradb_search pysradb allows to retrieve metadata, such as run accession numbers, from SRA and ENA based on multiple criteria. pysradb pysradb Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive. Deposition, Data retrieval Sequencing, Gene transcripts, Bioinformatics To update https://github.com/saketkc/pysradb Sequence Analysis pysradb_search iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/pysradb 1.4.2 pysradb 2.2.0 (0/1) (0/1) (1/1) True False +qiime_add_on qiime_collapse_samples, qiime_make_otu_table QIIME to perform microbial community analysis To update http://www.qiime.org Metagenomics qiime iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/qiime/ qiime 1.9.1 (0/2) (0/2) (2/2) True True +qiime_core qiime_align_seqs, qiime_alpha_diversity, qiime_alpha_rarefaction, qiime_assign_taxonomy, qiime_beta_diversity, qiime_beta_diversity_through_plots, qiime_compare_categories, qiime_core_diversity, qiime_count_seqs, qiime_extract_barcodes, qiime_filter_alignment, qiime_filter_fasta, qiime_filter_otus_from_otu_table, qiime_filter_samples_from_otu_table, qiime_filter_taxa_from_otu_table, qiime_jackknifed_beta_diversity, qiime_make_emperor, qiime_make_otu_heatmap, qiime_make_phylogeny, qiime_multiple_join_paired_ends, qiime_multiple_split_libraries_fastq, qiime_pick_closed_reference_otus, qiime_pick_open_reference_otus, qiime_pick_otus, qiime_pick_rep_set, qiime_plot_taxa_summary, qiime_split_libraries, qiime_split_libraries_fastq, qiime_summarize_taxa, qiime_summarize_taxa_through_plots, qiime_upgma_cluster, qiime_validate_mapping_file QIIME to perform microbial community analysis To update http://www.qiime.org Metagenomics qiime iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/qiime/ qiime 1.9.1 (0/32) (0/32) (32/32) True True +qq_tools qq_manhattan To update https://CRAN.R-project.org/package=qqman Visualization, Variant Analysis iuc 0.1.0 r-qqman 0.1.4 (0/1) (0/1) (0/1) True False +qualimap qualimap_bamqc, qualimap_counts, qualimap_multi_bamqc, qualimap_rnaseq qualimap QualiMap Platform-independent application written in Java and R that provides both a Graphical User Inteface (GUI) and a command-line interface to facilitate the quality control of alignment sequencing data. Sequencing quality control Data quality management To update http://qualimap.bioinfo.cipf.es/ Sequence Analysis, Transcriptomics, SAM qualimap iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/qualimap 2.2.2d qualimap 2.3 (4/4) (4/4) (4/4) True True +quast 51567.0 3567.0 quast Quast (Quality ASsessment Tool) evaluates genome assemblies. quast QUAST QUAST stands for QUality ASsessment Tool. It evaluates a quality of genome assemblies by computing various metrics and providing nice reports. Visualisation, Sequence assembly validation Sequence assembly Up-to-date http://quast.bioinf.spbau.ru/ Assembly quast iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/quast 5.2.0 quast 5.2.0 (1/1) (1/1) (1/1) True True +quickmerge quickmerge Merge long-read and hybrid assemblies to increase contiguity quickmerge quickmerge Quickmerge is a program that uses complementary information from genomes assembled with long reads in order to improve contiguity, and works with assemblies derived from both Pacific Biosciences or Oxford Nanopore. Quickmerge will even work with hybrid assemblies made by combining long reads and Illumina short reads. Genome assembly, Scaffolding, De-novo assembly, Genotyping Structural variation, Sequence assembly, DNA polymorphism, Whole genome sequencing, Genotype and phenotype Up-to-date https://github.com/mahulchak/quickmerge Assembly quickmerge galaxy-australia https://github.com/galaxyproject/tools-iuc/tree/master/tools/quickmerge 0.3 quickmerge 0.3 (0/1) (0/1) (0/1) True True +ragtag 2833.0 237.0 ragtag Reference-guided scaffolding of draft genomes tool. ragtag ragtag RagTag is a collection of software tools for scaffolding and improving modern genome assemblies. Genome assembly Sequence assembly Up-to-date https://github.com/malonge/RagTag Assembly ragtag iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ragtag 2.1.0 ragtag 2.1.0 (0/1) (0/1) (1/1) True False +rapidnj 176.0 14.0 rapidnj Galaxy wrapper for the RapidNJ tool rapidnj RapidNJ A tool for fast canonical neighbor-joining tree construction. Phylogenetic tree generation Phylogeny Up-to-date https://birc.au.dk/software/rapidnj/ Phylogenetics rapidnj iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/rapidnj 2.3.2 rapidnj 2.3.2 (1/1) (0/1) (1/1) True False +rasusa rasusa Randomly subsample sequencing reads to a specified coverage rasusa rasusa Produces an unbiased subsample of your reads Up-to-date https://github.com/mbhall88/rasusa Sequence Analysis rasusa iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/rasusa 0.8.0 rasusa 0.8.0 (0/1) (0/1) (0/1) False +raven 6902.0 262.0 raven Raven is a de novo genome assembler for long uncorrected reads. To update https://github.com/lbcb-sci/raven Assembly iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/raven 1.8.0 raven-assembler 1.8.3 (0/1) (1/1) (1/1) True False +raxml 6808.0 383.0 raxml RAxML - A Maximum Likelihood based phylogenetic inference raxml RAxML A tool for Phylogenetic Analysis and Post-Analysis of Large Phylogenies. Sequence analysis, Phylogenetic tree analysis Phylogenetics, Sequence analysis To update http://www.exelixis-lab.org/web/software/raxml/ Phylogenetics raxml iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/raxml 8.2.12 raxml 8.2.13 (1/1) (1/1) (1/1) True True +read_it_and_keep 3370.0 71.0 read_it_and_keep Rapid decontamination of SARS-CoV-2 sequencing reads To update https://github.com/GenomePathogenAnalysisService/read-it-and-keep Sequence Analysis read_it_and_keep iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/read-it-and-keep 0.2.2 read-it-and-keep 0.3.0 (1/1) (0/1) (1/1) True True +recentrifuge 331.0 48.0 recentrifuge """With Recentrifuge, researchers can analyze results from taxonomic classifiers using interactive charts with emphasis on the confidence level of the classifications.In addition to contamination-subtracted samples.Recentrifuge provides shared and exclusive taxa per sample,thus enabling robust contamination removal and comparative analysis in environmental and clinical metagenomics.""" Recentrifuge Recentrifuge Robust comparative analysis and contamination removal for metagenomics. Taxonomic classification, Expression analysis, Cross-assembly Metagenomics, Microbial ecology, Metagenomic sequencing Up-to-date https://github.com/khyox/recentrifuge Metagenomics recentrifuge iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/recentrifuge 1.14.0 recentrifuge 1.14.0 (0/1) (0/1) (1/1) True True +red 578.0 88.0 red Red (REpeat Detector) Up-to-date https://github.com/BioinformaticsToolsmith/Red Sequence Analysis red iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/red 2018.09.10 red 2018.09.10 (1/1) (1/1) (1/1) True False +repeatmasker repeatmasker_wrapper RepeatMasker is a program that screens DNA sequences for interspersed repeats and low complexity DNA sequences. repeatmasker RepeatMasker A program that screens DNA sequences for interspersed repeats and low complexity DNA sequences. The output of the program is a detailed annotation of the repeats that are present in the query sequence as well as a modified version of the query sequence in which all the annotated repeats have been masked (default: replaced by Ns). Genome annotation Sequence analysis, Sequence composition, complexity and repeats Up-to-date http://www.repeatmasker.org/ Sequence Analysis repeat_masker bgruening https://github.com/galaxyproject/tools-iuc/tree/master/tools/repeatmasker 4.1.5 repeatmasker 4.1.5 (1/1) (1/1) (1/1) True False +repeatmodeler 1177.0 217.0 repeatmodeler RepeatModeler - Model repetitive DNA To update https://www.repeatmasker.org/RepeatModeler/ Genome annotation repeatmodeler csbl https://github.com/galaxyproject/tools-iuc/tree/master/tools/repeatmodeler 2.0.5 (1/1) (1/1) (1/1) True False +ribowaltz ribowaltz_process, ribowaltz_plot Calculation of optimal P-site offsets, diagnostic analysis and visual inspection of ribosome profiling data riboWaltz riboWaltz riboWaltz is an R package for calculation of optimal P-site offsets, diagnostic analysis and visual inspection of ribosome profiling data. Computational biology To update https://github.com/LabTranslationalArchitectomics/riboWaltz Transcriptomics, RNA iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ribowaltz 1.2.0 ribowaltz 2.0 (0/2) (0/2) (2/2) True False +rnaquast 1110.0 109.0 rna_quast rnaQuast (RNA Quality Assessment Tool) evaluates genome assemblies. rnaQUAST rnaQUAST Quality assessment tool for de novo transcriptome assemblies. De-novo assembly, Transcriptome assembly, Sequence assembly validation Sequence assembly, Transcriptomics, RNA-seq Up-to-date https://github.com/ablab/rnaquast Assembly, RNA rnaquast iuc https://git.ufz.de/lehmanju/rnaquast 2.2.3 rnaquast 2.2.3 (0/1) (0/1) (1/1) True False +roary 12225.0 656.0 roary Roary the pangenome pipeline roary Roary A high speed stand alone pan genome pipeline, which takes annotated assemblies in GFF3 format (produced by Prokka (Seemann, 2014)) and calculates the pan genome. Genome assembly DNA, Genomics, Mapping Up-to-date https://sanger-pathogens.github.io/Roary/ Sequence Analysis roary iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/roary 3.13.0 roary 3.13.0 (1/1) (1/1) (1/1) True True +rseqc 135036.0 3269.0 rseqc_FPKM_count, rseqc_RNA_fragment_size, rseqc_RPKM_saturation, rseqc_bam2wig, rseqc_bam_stat, rseqc_clipping_profile, rseqc_deletion_profile, rseqc_geneBody_coverage, rseqc_geneBody_coverage2, rseqc_infer_experiment, rseqc_inner_distance, rseqc_insertion_profile, rseqc_junction_annotation, rseqc_junction_saturation, rseqc_mismatch_profile, rseqc_read_GC, rseqc_read_NVC, rseqc_read_distribution, rseqc_read_duplication, rseqc_read_hexamer, rseqc_read_quality, rseqc_tin an RNA-seq quality control package rseqc RSeQC Provides a number of useful modules that can comprehensively evaluate high throughput sequence data especially RNA-seq data. Some basic modules quickly inspect sequence quality, nucleotide composition bias, PCR bias and GC bias, while RNA-seq specific modules evaluate sequencing saturation, mapped reads distribution, coverage uniformity, strand specificity, transcript level RNA integrity etc. Data handling Sequencing To update https://code.google.com/p/rseqc/ Convert Formats, Sequence Analysis, RNA, Transcriptomics, Visualization rseqc nilesh https://github.com/galaxyproject/tools-iuc/tree/master/tools/rseqc 5.0.1 rseqc 5.0.3 (22/22) (22/22) (22/22) True True +ruvseq 1236.0 76.0 ruvseq Remove Unwanted Variation from RNA-Seq Data ruvseq RUVSeq This package implements the remove unwanted variation (RUV) methods for the normalization of RNA-Seq read counts between samples. Differential gene expression analysis Gene expression, RNA-seq To update https://www.bioconductor.org/packages/release/bioc/html/DESeq2.html Transcriptomics, RNA, Statistics ruvseq iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/ruvseq 1.26.0 bioconductor-ruvseq 1.36.0 (1/1) (0/1) (1/1) True False +salsa2 salsa A tool to scaffold long read assemblies with Hi-C SALSA SALSA > VERY_LOW CONFIDENCE! | > CORRECT NAME OF TOOL COULD ALSO BE 'chromosome-scale', 'reference-quality', 'Hi-C', 'scaffolder' | Integrating Hi-C links with assembly graphs for chromosome-scale assembly | SALSA: A tool to scaffold long read assemblies with Hi-C data | SALSA: A tool to scaffold long read assemblies with Hi-C | This code is used to scaffold your assemblies using Hi-C data. This version implements some improvements in the original SALSA algorithm. If you want to use the old version, it can be found in the old_salsa branch Genome assembly, De-novo assembly, Scaffolding Sequence assembly, DNA binding sites, Mapping Up-to-date https://github.com/marbl/SALSA Assembly salsa iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/salsa2 2.3 salsa2 2.3 (1/1) (1/1) (1/1) True False +sarscov2formatter 173.0 7.0 sarscov2formatter sarscov2formatter custom script Up-to-date https://github.com/nickeener/sarscov2formatter Sequence Analysis sarscov2formatter iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sarscov2formatter 1.0 sarscov2formatter 1.0 (1/1) (0/1) (1/1) True True +sarscov2summary 140.0 1.0 sarscov2summary sarscov2summary custom script To update https://github.com/nickeener/sarscov2summary Sequence Analysis sarscov2summary iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sarscov2summary 0.1 sarscov2summary 0.5 (1/1) (0/1) (1/1) True True +scanpy scanpy_cluster_reduce_dimension, scanpy_filter, scanpy_inspect, scanpy_normalize, scanpy_plot, scanpy_remove_confounders Scanpy – Single-Cell Analysis in Python scanpy SCANPY Scalable toolkit for analyzing single-cell gene expression data. It includes preprocessing, visualization, clustering, pseudotime and trajectory inference and differential expression testing. The Python-based implementation efficiently deals with datasets of more than one million cells. Differential gene expression analysis Gene expression, Cell biology, Genetics To update https://scanpy.readthedocs.io Transcriptomics, Sequence Analysis scanpy iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scanpy/ 1.9.6 scanpy 1.7.2 (6/6) (6/6) (6/6) True False +scater scater_create_qcmetric_ready_sce, scater_filter, scater_plot_dist_scatter, scater_plot_pca, scater_plot_tsne Scater (Single-Cell Analysis Toolkit for gene Expression data in R) is acollection of tools for doing various analyses of single-cell RNA-seq geneexpression data, with a focus on quality control and visualization. scater scater Pre-processing, quality control, normalization and visualization of single-cell RNA-seq data. Read pre-processing, Sequencing quality control, Sequence visualisation RNA-seq, Quality affairs, Molecular genetics To update http://bioconductor.org/packages/scater/ Transcriptomics, RNA, Visualization iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scater 1.22.0 bioconductor-scater 1.30.1 (0/5) (5/5) (5/5) True False +schicexplorer schicexplorer_schicadjustmatrix, schicexplorer_schiccluster, schicexplorer_schicclustercompartments, schicexplorer_schicclusterminhash, schicexplorer_schicclustersvl, schicexplorer_schicconsensusmatrices, schicexplorer_schiccorrectmatrices, schicexplorer_schiccreatebulkmatrix, schicexplorer_schicdemultiplex, schicexplorer_schicinfo, schicexplorer_schicmergematrixbins, schicexplorer_schicmergetoscool, schicexplorer_schicnormalize, schicexplorer_schicplotclusterprofiles, schicexplorer_schicplotconsensusmatrices, schicexplorer_schicqualitycontrol scHiCExplorer: Set of programs to process, analyze and visualize scHi-C data. To update https://github.com/joachimwolff/schicexplorer Sequence Analysis, Transcriptomics, Visualization schicexplorer iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/schicexplorer 4 schicexplorer 7 (0/16) (0/16) (16/16) True False +scikit-bio scikit_bio_diversity_beta_diversity scikit-bio: an open-source, BSD-licensed, python package providing data structures, algorithms, and educational resources for bioinformatics Up-to-date http://scikit-bio.org/ Sequence Analysis scikit_bio iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scikit_bio 0.4.2 scikit-bio 0.4.2 (1/1) (0/1) (0/1) True False +scoary 676.0 61.0 scoary Scoary calculates the assocations between all genes in the accessory genome and the traits. Up-to-date https://github.com/AdmiralenOla/Scoary Metagenomics scoary iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scoary 1.6.16 scoary 1.6.16 (0/1) (0/1) (1/1) True True +scpipe 628.0 11.0 scpipe A flexible preprocessing pipeline for single-cell RNA-sequencing data scpipe scPipe A preprocessing pipeline for single cell RNA-seq data that starts from the fastq files and produces a gene count matrix with associated quality control information. It can process fastq data generated by CEL-seq, MARS-seq, Drop-seq, Chromium 10x and SMART-seq protocols. Genome annotation, Validation, Alignment, Visualisation Gene expression, RNA-seq, Sequencing To update http://bioconductor.org/packages/release/bioc/html/scPipe.html Transcriptomics, RNA, Statistics scpipe iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/scpipe 1.0.0+galaxy2 bioconductor-scpipe 2.2.0 (1/1) (0/1) (1/1) True False +semibin 183.0 10.0 semibin_bin, semibin_concatenate_fasta, semibin_generate_cannot_links, semibin_generate_sequence_features, semibin, semibin_train SemiBin: Semi-supervised Metagenomic Binning Using Siamese Neural Networks semibin SemiBin Command tool for metagenomic binning with semi-supervised deep learning using information from reference genomes. Sequence assembly, Read binning Metagenomics, Machine learning, Microbial ecology, Sequence assembly Up-to-date https://semibin.readthedocs.io/en/latest/ Metagenomics semibin iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/semibin 2.0.2 semibin 2.0.2 (0/6) (0/6) (6/6) True True +seq2hla 288.0 16.0 seq2hla Precision HLA typing and expression from RNAseq data seq2hla Seq2HLA seq2HLA is a computational tool to determine Human Leukocyte Antigen (HLA) directly from existing and future short RNA-Seq reads. It takes standard RNA-Seq sequence reads in fastq format as input, uses a bowtie index comprising known HLA alleles and outputs the most likely HLA class I and class II types, a p-value for each call, and the expression of each class. Read mapping, Genetic variation analysis Transcriptomics, Mapping Up-to-date https://github.com/TRON-Bioinformatics/seq2HLA Sequence Analysis seq2hla iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seq2hla 2.3 seq2hla 2.3 (0/1) (0/1) (1/1) True False +seqcomplexity 68.0 16.0 seqcomplexity Sequence complexity for raw reads Up-to-date https://github.com/stevenweaver/seqcomplexity Sequence Analysis iuc https://github.com/stephenshank/tools-iuc/tree/seqcomplexity/tools/seqcomplexity/ 0.1.2 seqcomplexity 0.1.2 (1/1) (0/1) (1/1) True False +seqkit seqkit_fx2tab, seqkit_locate, seqkit_stats A cross-platform and ultrafast toolkit for FASTA/Q file manipulation seqkit seqkit FASTA and FASTQ are basic and ubiquitous formats for storing nucleotide and protein sequences. Common manipulations of FASTA/Q file include converting, searching, filtering, deduplication, splitting, shuffling, and sampling. Existing tools only implement some of these manipulations, and not particularly efficiently, and some are only available for certain operating systems. Furthermore, the complicated installation process of required packages and running environments can render these programs less user friendly. SeqKit demonstrates competitive performance in execution time and memory usage compared to similar tools. The efficiency and usability of SeqKit enable researchers to rapidly accomplish common FASTA/Q file manipulations. DNA transcription, Sequence trimming, DNA translation, Sequence conversion Database management, Sequence analysis To update https://bioinf.shenwei.me/seqkit/ Sequence Analysis seqkit iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqkit 2.3.1 seqkit 2.7.0 (0/3) (0/3) (3/3) True True +seqprep seqprep Tool for merging paired-end Illumina reads and trimming adapters. seqprep SeqPrep Strips adapters and optionally merges overlapping paired-end (or paired-end contamination in mate-pair libraries) illumina style reads. Nucleic acid design Genomics, Sequence assembly, Sequencing, Probes and primers Up-to-date https://github.com/jstjohn/SeqPrep Fastq Manipulation, Sequence Analysis seqprep iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqprep 1.3.2 seqprep 1.3.2 (0/1) (0/1) (1/1) False +seqsero2 12.0 seqsero2 Salmonella serotype prediction from genome sequencing data Up-to-date https://github.com/denglab/SeqSero2 Sequence Analysis seqsero2 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqsero2 1.2.1 seqsero2 1.2.1 (0/1) (0/1) (1/1) False +seqtk 59668.0 753.0 seqtk_comp, seqtk_cutN, seqtk_dropse, seqtk_fqchk, seqtk_hety, seqtk_listhet, seqtk_mergefa, seqtk_mergepe, seqtk_mutfa, seqtk_randbase, seqtk_sample, seqtk_seq, seqtk_subseq, seqtk_telo, seqtk_trimfq Toolkit for processing sequences in FASTA/Q formats seqtk seqtk A tool for processing sequences in the FASTA or FASTQ format. It parses both FASTA and FASTQ files which can also be optionally compressed by gzip. Data handling, Sequence file editing Data management Up-to-date https://github.com/lh3/seqtk Sequence Analysis seqtk iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqtk 1.4 seqtk 1.4 (15/15) (15/15) (15/15) True False +seqwish 271.0 seqwish Alignment to variation graph inducer To update https://github.com/ekg/seqwish Sequence Analysis, Variant Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seqwish/ 0.7.5 seqwish 0.7.9 (0/1) (0/1) (1/1) True False +seurat 1543.0 66.0 seurat A toolkit for quality control, analysis, and exploration of single cell RNA sequencing data To update https://github.com/satijalab/seurat Transcriptomics, RNA, Statistics seurat iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/seurat 4.3.0.1 r-seurat 3.0.2 (1/1) (1/1) (1/1) True False +shasta 763.0 154.0 shasta Fast de novo assembly of long read sequencing data To update https://github.com/chanzuckerberg/shasta Assembly, Nanopore shasta iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/shasta 0.6.0 shasta 0.11.1 (0/1) (1/1) (1/1) True False +shorah shorah_amplicon Reconstruct haplotypes using ShoRAH in amplicon mode shorah ShoRAH Inference of a population from a set of short reads. The package contains programs that support mapping of reads to a reference genome, correcting sequencing errors by locally clustering reads in small windows of the alignment, reconstructing a minimal set of global haplotypes that explain the reads, and estimating the frequencies of the inferred haplotypes. Haplotype mapping, Variant calling Metagenomics, Sequencing, Genetics To update https://github.com/cbg-ethz/shorah/blob/master/README.md Sequence Analysis shorah_amplicon iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/shorah 1.1.3 shorah 1.99.2 (0/1) (0/1) (0/1) True False +shovill 41600.0 1008.0 shovill Faster de novo assembly pipeline based around Spades shovill shovill Shovill is a pipeline for assembly of bacterial isolate genomes from Illumina paired-end reads. Shovill uses SPAdes at its core, but alters the steps before and after the primary assembly step to get similar results in less time. Shovill also supports other assemblers like SKESA, Velvet and Megahit, so you can take advantage of the pre- and post-processing the Shovill provides with those too. Genome assembly Genomics, Microbiology, Sequence assembly Up-to-date https://github.com/tseemann/shovill Assembly shovill iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/shovill 1.1.0 shovill 1.1.0 (1/1) (1/1) (1/1) True True +sickle 14982.0 269.0 sickle A windowed adaptive trimming tool for FASTQ files using quality sickle sickle A tool that uses sliding windows along with quality and length thresholds to determine when quality is sufficiently low to trim the 3'-end of reads and also determines when the quality is sufficiently high enough to trim the 5'-end of reads. Sequence trimming Data quality management To update https://github.com/najoshi/sickle Fastq Manipulation, Sequence Analysis sickle iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sickle 1.33.2 sickle-trim 1.33 (1/1) (0/1) (1/1) True False +sina 1128.0 42.0 sina SINA reference based multiple sequence alignment sina SINA Aligns and optionally taxonomically classifies your rRNA gene sequences.Reference based multiple sequence alignment Sequence alignment analysis, Multiple sequence alignment, Taxonomic classification, Structure-based sequence alignment Sequencing, RNA, Nucleic acid structure analysis, Taxonomy, Sequence analysis, Taxonomy Up-to-date https://sina.readthedocs.io/en/latest/ Sequence Analysis sina iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sina 1.7.2 sina 1.7.2 (1/1) (0/1) (1/1) True False +sinto sinto_barcode, sinto_fragments Sinto single-cell analysis tools To update https://github.com/timoast/sinto Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sinto 0.9.0 sinto 0.10.0 (2/2) (0/2) (2/2) True False +slamdunk 361.0 2.0 alleyoop, slamdunk Slamdunk maps and quantifies SLAMseq reads Up-to-date http://t-neumann.github.io/slamdunk RNA, Transcriptomics, Sequence Analysis, Next Gen Mappers slamdunk iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/slamdunk 0.4.3 slamdunk 0.4.3 (2/2) (0/2) (2/2) True False +sleuth 64.0 8.0 sleuth Sleuth is a program for differential analysis of RNA-Seq data. sleuth sleuth A statistical model and software application for RNA-seq differential expression analysis. Expression data visualisation, Differential gene expression analysis, Gene expression profiling, Statistical calculation RNA-seq, Gene expression, Statistics and probability Up-to-date https://github.com/pachterlab/sleuth Transcriptomics, RNA, Statistics sleuth iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/sleuth 0.30.1 r-sleuth 0.30.1 (0/1) (0/1) (1/1) True False +smallgenomeutilities smgu_frameshift_deletions_checks Set of utilities for manipulating small viral genome data. v-pipe V-pipe Bioinformatics pipeline for the analysis of next-generation sequencing data derived from intra-host viral populations. Read pre-processing, Sequence alignment, Genetic variation analysis Genomics, Population genetics, Workflows, Virology, Sequencing Up-to-date https://github.com/cbg-ethz/smallgenomeutilities Sequence Analysis smallgenomeutilities iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/smallgenomeutilities 0.4.0 smallgenomeutilities 0.4.0 (0/1) (0/1) (1/1) True True +smudgeplot 203.0 22.0 smudgeplot Inference of ploidy and heterozygosity structure using whole genome sequencing smudgeplots Smudgeplots Reference-free profiling of polyploid genomes | Inference of ploidy and heterozygosity structure using whole genome sequencing data | Smudgeplots are computed from raw or even better from trimmed reads and show the haplotype structure using heterozygous kmer pairs. For example: | This tool extracts heterozygous kmer pairs from kmer dump files and performs gymnastics with them. We are able to disentangle genome structure by comparing the sum of kmer pair coverages (CovA + CovB) to their relative coverage (CovA / (CovA + CovB)). Such an approach also allows us to analyze obscure genomes with duplications, various ploidy levels, etc | GenomeScope 2.0 and Smudgeplots: Reference-free profiling of polyploid genomes Timothy Rhyker Ranallo-Benavidez, Kamil S. Jaron, Michael C. Schatz bioRxiv 747568; doi: https://doi.org/10.1101/747568 Sequence trimming, Genotyping, k-mer counting Sequence assembly, Genetic variation, Mathematics Up-to-date https://github.com/KamilSJaron/smudgeplot Assembly smudgeplot galaxy-australia https://github.com/galaxyproject/tools-iuc 0.2.5 smudgeplot 0.2.5 (1/1) (1/1) (1/1) True False +snap snap, snap_training SNAP is a general purpose gene finding program suitable for both eukaryotic and prokaryotic genomes. snap SNAP The Semi-HMM-based Nucleic Acid Parser is a gene prediction tool. Gene prediction DNA, DNA polymorphism, Genetics Up-to-date https://github.com/KorfLab/SNAP Sequence Analysis snap iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/snap 2013_11_29 snap 2013_11_29 (1/2) (1/2) (1/2) True True +sniffles 919.0 58.0 sniffles Galaxy wrapper for sniffles sniffles Sniffles An algorithm for structural variation detection from third generation sequencing alignment. Sequence analysis, Structural variation detection DNA structural variation, Sequencing To update https://github.com/fritzsedlazeck/Sniffles Sequence Analysis sniffles iuc https://github.com/galaxyproject/tools-iuc 1.0.12 sniffles 2.2 (1/1) (1/1) (1/1) True False +snipit 669.0 22.0 snipit Summarise snps relative to a reference sequence snipit snipit Summarise snps relative to a reference sequence Base position variability plotting Virology Up-to-date https://github.com/aineniamh/snipit Variant Analysis, Sequence Analysis snipit iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/snipit 1.2 snipit 1.2 (0/1) (0/1) (1/1) True False +snippy 105708.0 1372.0 snippy_core, snippy, snippy_clean_full_aln Contains the snippy tool for characterising microbial snps snippy snippy Rapid haploid variant calling and core SNP phylogeny generation. Phylogenetic tree visualisation, Phylogenetic tree generation, Variant calling Genomics, Model organisms, DNA polymorphism, Phylogenetics To update https://github.com/tseemann/snippy Sequence Analysis snippy iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/snippy snippy 4.6.0 (3/3) (3/3) (3/3) True True +socru 621.0 13.0 socru Order and orientation of complete bacterial genomes To update https://github.com/quadram-institute-bioscience/socru Sequence Analysis socru iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/socru 2.1.7 socru 2.2.4 (1/1) (0/1) (1/1) True False +sonneityping 1.0 1.0 sonneityping Scripts for parsing Mykrobe predict results for Shigella sonnei. Up-to-date https://github.com/katholt/sonneityping Sequence Analysis sonneityping iuc https://github.com/katholt/sonneityping 20210201 sonneityping 20210201 (0/1) (0/1) (1/1) True True +spades 58834.0 2309.0 spades_biosyntheticspades, spades_coronaspades, spades_metaplasmidspades, metaspades, spades_metaviralspades, spades_plasmidspades, rnaspades, spades_rnaviralspades, spades SPAdes is an assembly toolkit containing various assembly pipelines. It implements the following 4 stages: assembly graph construction, k-bimer adjustment, construction of paired assembly graph and contig construction. biosyntheticspades biosyntheticSPAdes biosyntheticSPAdes - biosynthetic gene cluster assembly with paired-end reads Sequence assembly Sequence assembly, Sequence sites, features and motifs, Genetic engineering Up-to-date https://github.com/ablab/spades Assembly, RNA, Metagenomics spades iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/spades 3.15.5 spades 3.15.5 (9/9) (9/9) (9/9) True True +spaln 446.0 34.0 list_spaln_tables, spaln Spaln (space-efficient spliced alignment) maps and aligns a set of cDNA or protein sequences onto a whole genomic sequence. To update http://www.genome.ist.i.kyoto-u.ac.jp/~aln_user/spaln/ Sequence Analysis, Genome annotation spaln iuc https://github.com/ogotoh/spaln 2.4.9 python (2/2) (0/2) (2/2) True False +spotyping 1278.0 12.0 spotyping SpoTyping allows fast and accurate in silico Mycobacterium spoligotyping from sequence reads spotyping SpoTyping Fast and accurate in silico Mycobacterium spoligotyping from sequence reads. Variant pattern analysis Microbiology, Sequencing, Sequence composition, complexity and repeats, Genetic variation Up-to-date https://github.com/xiaeryu/SpoTyping-v2.0 Sequence Analysis spotyping iuc https://github.com/xiaeryu/SpoTyping-v2.0/tree/master/SpoTyping-v2.0-commandLine 2.1 spotyping 2.1 (0/1) (0/1) (1/1) True True +srst2 205.0 22.0 srst2 SRST2 Short Read Sequence Typing for Bacterial Pathogens To update http://katholt.github.io/srst2/ Metagenomics srst2 iuc https://github.com/katholt/srst2 0.2.0 samtools 1.19.2 (0/1) (0/1) (1/1) True True +stacks stacks_assembleperead, stacks_clonefilter, stacks_cstacks, stacks_denovomap, stacks_genotypes, stacks_populations, stacks_procrad, stacks_pstacks, stacks_refmap, stacks_rxstacks, stacks_sstacks, stacks_stats, stacks_ustacks Stacks is a software pipeline for building loci from short-read sequences, such as RAD-seq stacks Stacks Developed to work with restriction enzyme based sequence data, such as RADseq, for building genetic maps and conducting population genomics and phylogeography analysis. Data handling Mapping, Population genetics To update http://catchenlab.life.illinois.edu/stacks/ Sequence Analysis stacks iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/stacks stacks 2.65 (0/13) (13/13) (13/13) True False +stacks2 stacks2_clonefilter, stacks2_cstacks, stacks2_denovomap, stacks2_gstacks, stacks2_kmerfilter, stacks2_populations, stacks2_procrad, stacks2_refmap, stacks2_shortreads, stacks2_sstacks, stacks2_tsv2bam, stacks2_ustacks Stacks is a software pipeline for building loci from short-read sequences, such as RAD-seq To update http://catchenlab.life.illinois.edu/stacks/ Sequence Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/stacks2 2.55 stacks 2.65 (0/12) (12/12) (12/12) True False +star_fusion 1212.0 35.0 star_fusion STAR Fusion detects fusion genes in RNA-Seq data after running RNA-STAR To update Sequence Analysis, Transcriptomics star_fusion iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/star_fusion 0.5.4-3+galaxy1 star-fusion 1.12.0 (1/1) (1/1) (1/1) True False +structure 2623.0 59.0 structure for using multi-locus genotype data to investigate population structure. structure Structure The program structureis a free software package for using multi-locus genotype data to investigate population structure. Its uses include inferring the presence of distinct populations, assigning individuals to populations, studying hybrid zones, identifying migrants and admixed individuals, and estimating population allele frequencies in situations where many individuals are migrants or admixed. Genetic variation analysis Population genetics Up-to-date Phylogenetics, Variant Analysis structure iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/structure 2.3.4 structure 2.3.4 (0/1) (0/1) (1/1) True True +structureharvester structureharvester for parsing STRUCTURE outputs and for performing the Evanno method Up-to-date Phylogenetics, Variant Analysis structureharvester iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/structureharvester 0.6.94 structureharvester 0.6.94 (0/1) (0/1) (0/1) True False +syndiva 30.0 2.0 syndiva SynDivA was developed to analyze the diversity of synthetic libraries of a Fibronectin domain. To update Proteomics syndiva iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/SynDivA 1.0 clustalo 1.2.4 (0/1) (0/1) (1/1) True False +tasmanian_mismatch tasmanian_mismatch Analysis of positional mismatches Up-to-date Sequence Analysis tasmanian_mismatch iuc https://github.com/nebiolabs/tasmanian-mismatch 1.0.7 tasmanian-mismatch 1.0.7 (0/1) (0/1) (0/1) True False +taxonomy_filter_refseq taxonomy_filter_refseq Filter RefSeq by taxonomy To update https://github.com/pvanheus/ncbitaxonomy Sequence Analysis, Genome annotation taxonomy_filter_refseq iuc https://github.com/galaxyproject/tools-iuc 0.3.0 rust-ncbitaxonomy 1.0.7 (0/1) (0/1) (0/1) True False +taxonomy_krona_chart 27426.0 1801.0 taxonomy_krona_chart Krona pie chart from taxonomic profile krona Krona Krona creates interactive HTML5 charts of hierarchical data (such as taxonomic abundance in a metagenome). Visualisation Metagenomics To update http://sourceforge.net/projects/krona/ Assembly taxonomy_krona_chart crs4 https://github.com/galaxyproject/tools-iuc/tree/master/tools/taxonomy_krona_chart 2.7.1+galaxy0 krona 2.8.1 (1/1) (1/1) (1/1) True True +tb-profiler tb_profiler_profile Processes M. tuberculosis sequence data to infer strain type and identify known drug resistance markers. To update https://github.com/jodyphelan/TBProfiler Sequence Analysis tbprofiler iuc https://github.com/galaxyproject/tools-iuc/blob/master/tools/tb-profiler 4.4.1 tb-profiler 5.0.1 (1/1) (1/1) (1/1) True True +tbl2gff3 1584.0 229.0 tbl2gff3 Table to GFF3 To update https://github.com/galaxyproject/tools-iuc/tree/master/tools/tbl2gff3 Convert Formats, Sequence Analysis tbl2gff3 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/tbl2gff3 1.2 bcbiogff 0.6.6 (0/1) (1/1) (1/1) True False +te_finder 81.0 7.0 te_finder Transposable element insertions finder tefinder TEfinder A Bioinformatics Pipeline for Detecting New Transposable Element Insertion Events in Next-Generation Sequencing Data.A bioinformatics tool for detecting novel transposable element insertions.TEfinder uses discordant reads to detect novel transposable element insertion events in paired-end sample sequencing data. Genome indexing, Variant calling, PCR primer design Sequencing, Mobile genetic elements, Workflows, Evolutionary biology, Genetic variation To update https://github.com/VistaSohrab/TEfinder Sequence Analysis te_finder iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/te_finder/ 1.0.1 samtools 1.19.2 (0/1) (0/1) (1/1) True False +telescope telescope_assign Single locus resolution of Transposable ELEment expression. Telescope-expression Telescope Telescope is a tool for the characterization of the retrotranscriptome by accurate estimation of transposable element expression and the quantification of transposable element expression using RNA-seq.It can be used for Statistical Performance of TE Quantification Methods.All scripts needed to examine the sensitivity and biases of computational approaches for quantifying TE expression: 1) unique counts, 2) best counts, 3) RepEnrich, 4) TEtranscripts, 5) RSEM, 6) SalmonTE, and 7) Telescope. Essential dynamics, Sequence trimming, RNA-Seq quantification, Expression analysis, Read mapping RNA-Seq, Transcriptomics, Mapping, Gene transcripts, Sequence assembly Up-to-date https://github.com/mlbendall/telescope/ Genome annotation telescope_assign iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/telescope 1.0.3 telescope 1.0.3 (0/1) (0/1) (0/1) True False +tetoolkit tetoolkit_tetranscripts The TEToolkit suite improves the bioinformatic analysis of repetitive sequences, particularly transposable elements, in order to elucidate novel (and previously ignored) biological insights of their functions in development and diseases. Up-to-date http://hammelllab.labsites.cshl.edu/software/ Sequence Analysis tetoolkit iuc https://github.com/mhammell-laboratory/TEtranscripts 2.2.3 tetranscripts 2.2.3 (0/1) (1/1) (1/1) True False +tetyper 69.0 8.0 tetyper Type a specific transposable element (TE) of interest from paired-end sequencing data. Up-to-date https://github.com/aesheppard/TETyper Sequence Analysis tetyper iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/tetyper 1.1 tetyper 1.1 (1/1) (0/1) (1/1) True False +tn93 113.0 7.0 tn93_readreduce, tn93, tn93_cluster, tn93_filter Compute distances between sequences To update https://github.com/veg/tn93/ Sequence Analysis tn93 iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/tn93/ 1.0.6 tn93 1.0.13 (4/4) (0/4) (4/4) True False +transdecoder 5468.0 348.0 transdecoder TransDecoder finds coding regions within transcripts TransDecoder TransDecoder TransDecoder identifies candidate coding regions within transcript sequences, such as those generated by de novo RNA-Seq transcript assembly using Trinity, or constructed based on RNA-Seq alignments to the genome using Tophat and Cufflinks. Coding region prediction, de Novo sequencing, De-novo assembly Genomics, Gene transcripts, RNA-Seq, Gene expression, Sequence assembly, Whole genome sequencing To update https://transdecoder.github.io/ Transcriptomics, RNA transdecoder iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/transdecoder 5.5.0 transdecoder 5.7.1 (1/1) (1/1) (1/1) True False +transit gff_to_prot, transit_gumbel, transit_hmm, transit_resampling, transit_tn5gaps TRANSIT transit TRANSIT A tool for the analysis of Tn-Seq data. It provides an easy to use graphical interface and access to three different analysis methods that allow the user to determine essentiality in a single condition as well as between conditions. Transposon prediction DNA, Sequencing, Mobile genetic elements To update https://github.com/mad-lab/transit/ Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/transit/ 3.0.2 transit 3.2.3 (5/5) (5/5) (5/5) True False +transtermhp 229.0 5.0 transtermhp Finds rho-independent transcription terminators in bacterial genomes To update Sequence Analysis transtermhp iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/transtermhp transtermhp 2.09 (1/1) (0/1) (1/1) True True +trinity 12733.0 678.0 trinity_abundance_estimates_to_matrix, trinity_align_and_estimate_abundance, trinity_analyze_diff_expr, trinity_contig_exn50_statistic, trinity_define_clusters_by_cutting_tree, describe_samples, trinity_filter_low_expr_transcripts, trinity_gene_to_trans_map, trinity_run_de_analysis, trinity_samples_qccheck, trinity_super_transcripts, trinity, trinity_stats Trinity represents a method for the efficient and robust de novo reconstruction of transcriptomes from RNA-seq datahttps://github.com/trinityrnaseq/trinityrnaseq trinity Trinity Trinity is a transcriptome assembler which relies on three different tools, inchworm an assembler, chrysalis which pools contigs and butterfly which amongst others compacts a graph resulting from butterfly with reads. Transcriptome assembly Transcriptomics, Gene expression, Gene transcripts Up-to-date https://github.com/trinityrnaseq/trinityrnaseq Transcriptomics, RNA iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/trinity 2.15.1 trinity 2.15.1 (9/13) (13/13) (13/13) True False +trinotate 1796.0 151.0 trinotate Trinotate is a comprehensive annotation suite designed for automatic functional annotation of de novo transcriptomes. trinotate Trinotate Comprehensive annotation suite designed for automatic functional annotation of transcriptomes, particularly de novo assembled transcriptomes, from model or non-model organisms. Gene functional annotation Gene expression, Transcriptomics To update https://trinotate.github.io/ Transcriptomics, RNA trinotate iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/trinotate 3.2.2 trinotate 4.0.2 (1/1) (1/1) (1/1) True False +trycycler trycycler_cluster, trycycler_consensus, trycycler_partition, trycycler_reconcile_msa, trycycler_subsample Trycycler toolkit wrappers Up-to-date https://github.com/rrwick/Trycycler Assembly trycycler iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/trycycler 0.5.4 trycycler 0.5.4 (0/5) (5/5) (5/5) True False +tsebra 5.0 tsebra This tool has been developed to combine BRAKER predictions. Up-to-date https://github.com/Gaius-Augustus/TSEBRA Genome annotation iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/tsebra 1.1.2.3 tsebra 1.1.2.3 (0/1) (0/1) (1/1) True False +ucsc_blat ucsc_blat Standalone blat sequence search command line tool blat BLAT Fast, accurate spliced alignment of DNA sequences. Sequence alignment Sequence analysis To update http://genome.ucsc.edu/goldenPath/help/blatSpec.html Sequence Analysis ucsc_blat yating-l 377 ucsc-blat 445 (0/1) (0/1) (0/1) True False +umi_tools umi_tools_count, umi_tools_dedup, umi_tools_extract, umi_tools_group, umi_tools_whitelist UMI-tools extract - Extract UMIs from fastq umi-tools UMI-tools Tools for handling Unique Molecular Identifiers in NGS data sets. Sequencing quality control NGS, Sequence sites, features and motifs, Quality affairs To update https://github.com/CGATOxford/UMI-tools Sequence Analysis, Transcriptomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/umi_tools 1.1.2 umi_tools 1.1.5 (5/5) (5/5) (5/5) True False +unicycler 65732.0 1558.0 unicycler Unicycler is a hybrid assembly pipeline for bacterial genomes. unicycler Unicycler A tool for assembling bacterial genomes from a combination of short (2nd generation) and long (3rd generation) sequencing reads. Genome assembly, Aggregation Microbiology, Genomics, Sequencing, Sequence assembly Up-to-date https://github.com/rrwick/Unicycler Assembly unicycler iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/unicycler 0.5.0 unicycler 0.5.0 (1/1) (1/1) (1/1) True True +usher 1060.0 5.0 usher_matutils, usher UShER toolkit wrappers To update https://github.com/yatisht/usher Phylogenetics usher iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/usher 0.2.1 usher 0.6.3 (0/2) (0/2) (2/2) True True +valet 637.0 20.0 valet A pipeline for detecting mis-assemblies in metagenomic assemblies. To update https://github.com/marbl/VALET Metagenomics valet iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/valet valet 1.0 (1/1) (0/1) (1/1) True True +vapor 3164.0 94.0 vapor Classify Influenza samples from raw short read sequence data vapor VAPOR VAPOR is a tool for classification of Influenza samples from raw short read sequence data for downstream bioinformatics analysis. VAPOR is provided with a fasta file of full-length sequences (> 20,000) for a given segment, a set of reads, and attempts to retrieve a reference that is closest to the sample strain. Data retrieval, De-novo assembly, Read mapping Whole genome sequencing, Mapping, Sequence assembly Up-to-date https://github.com/connor-lab/vapor Sequence Analysis vapor iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vapor 1.0.2 vapor 1.0.2 (1/1) (0/1) (1/1) True True +varvamp varvamp Variable VirusAMPlicons (varVAMP) is a tool to design primers for highly diverse viruses varvamp varVAMP variable VirusAMPlicons (varVAMP) is a tool to design primers for highly diverse viruses. The input is an alignment of your viral (full-genome) sequences. PCR primer design Virology Up-to-date https://github.com/jonas-fuchs/varVAMP/ Sequence Analysis varvamp iuc https://github.com/jonas-fuchs/varVAMP 1.1.1 varvamp 1.1.1 (0/1) (0/1) (1/1) False +vegan vegan_diversity, vegan_fisher_alpha, vegan_rarefaction To update https://cran.r-project.org/package=vegan Metagenomics iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vegan/ 2.4-3 r-vegan 2.3_4 (3/3) (0/3) (3/3) True True +velvet 12218.0 1280.0 velvetg, velveth de novo genomic assembler specially designed for short read sequencing technologies velvet Velvet A de novo genomic assembler specially designed for short read sequencing technologies, such as Solexa or 454 or SOLiD. Formatting, De-novo assembly Sequence assembly To update https://www.ebi.ac.uk/~zerbino/velvet/ Assembly velvet devteam https://github.com/galaxyproject/tools-iuc/tree/master/tools/velvet velvet 1.2.10 (2/2) (2/2) (2/2) True True +velvet_optimiser velvetoptimiser Automatically optimize Velvet assemblies velvetoptimiser VelvetOptimiser This tool is designed to run as a wrapper script for the Velvet assembler (Daniel Zerbino, EBI UK) and to assist with optimising the assembly. Optimisation and refinement, Sequence assembly Genomics, Sequence assembly To update Assembly velvetoptimiser simon-gladman https://github.com/galaxyproject/tools-iuc/tree/master/tools/velvetoptimiser 2.2.6+galaxy2 velvet 1.2.10 (1/1) (1/1) (1/1) True True +verkko 22.0 9.0 verkko Telomere-to-telomere assembly pipeline To update https://github.com/marbl/verkko Assembly verkko iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/verkko 1.3.1 verkko 2.0 (0/1) (0/1) (1/1) True False +vg vg_convert, vg_deconstruct, vg_view Variation graph data structures, interchange formats, alignment, genotyping, and variant calling methods To update https://github.com/vgteam/vg Sequence Analysis, Variant Analysis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vg 1.23.0 vg 1.54.0 (0/3) (0/3) (3/3) True False +volcanoplot 30946.0 1749.0 volcanoplot Tool to create a Volcano Plot To update Visualization, Transcriptomics, Statistics volcanoplot iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/volcanoplot 0.0.5 r-ggplot2 2.2.1 (1/1) (1/1) (1/1) True False +vsearch 8507.0 182.0 vsearch_alignment, vsearch_chimera_detection, vsearch_clustering, vsearch_dereplication, vsearch_masking, vsearch_search, vsearch_shuffling, vsearch_sorting VSEARCH including searching, clustering, chimera detection, dereplication, sorting, masking and shuffling of sequences. vsearch VSEARCH High-throughput search and clustering sequence analysis tool. It supports de novo and reference based chimera detection, clustering, full-length and prefix dereplication, reverse complementation, masking, all-vs-all pairwise global alignment, exact and global alignment searching, shuffling, subsampling and sorting. It also supports FASTQ file analysis, filtering and conversion. DNA mapping, Chimera detection Metagenomics, Sequence analysis To update https://github.com/torognes/vsearch Sequence Analysis vsearch iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vsearch 2.8.3 vsearch 2.27.0 (8/8) (8/8) (8/8) True True +vsnp vsnp_add_zero_coverage, vsnp_build_tables, vsnp_determine_ref_from_data, vsnp_get_snps, vsnp_statistics The vSNP tools are critical components of several workflows that validate SNPs and produce annotatedSNP tables and corresponding phylogenetic trees. To update https://github.com/USDA-VS/vSNP Sequence Analysis vsnp iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/vsnp 3.0.6 pysam 0.22.0 (0/5) (0/5) (0/5) True False +weather_app simple_weather provides simple weather in text format To update http://wttr.in/ Visualization, Web Services simpleweather iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/weather_app 0.1.2 curl (0/1) (0/1) (0/1) True False +windowmasker 85.0 windowmasker_mkcounts, windowmasker_ustat Identify repetitive regions using WindowMasker To update https://www.ncbi.nlm.nih.gov/IEB/ToolBox/CPP_DOC/lxr/source/src/app/winmasker/ Sequence Analysis windowmasker iuc https://github.com/galaxyproject/tools-iuc/tree/main/tools/windowmasker/ 1.0 blast 2.15.0 (0/2) (2/2) (2/2) False +yahs 344.0 64.0 yahs Yet Another Hi-C scaffolding tool Up-to-date https://github.com/c-zhou/yahs Assembly yahs iuc https://github.com/galaxyproject/tools-iuc/tree/master/tools/yahs 1.2a.2 yahs 1.2a.2 (1/1) (1/1) (1/1) True False +bamtools 14039.0 208.0 bamtools Operate on and transform BAM datasets in various ways using bamtools Up-to-date https://github.com/pezmaster31/bamtools Sequence Analysis, SAM bamtools devteam https://github.com/galaxyproject/tools-iuc/tree/main/tool_collections/bamtools/bamtools 2.5.2 bamtools 2.5.2 (1/1) (0/1) (1/1) True True +bamtools_filter 114845.0 1195.0 bamFilter Filter BAM datasets on various attributes using bamtools filter Up-to-date https://github.com/pezmaster31/bamtools Sequence Analysis, SAM bamtools_filter devteam https://github.com/galaxyproject/tools-iuc/tree/main/tool_collections/bamtools/bamtools_filter 2.5.2 bamtools 2.5.2 (1/1) (1/1) (1/1) True False +bamtools_split 1434.0 47.0 bamtools_split_mapped, bamtools_split_paired, bamtools_split_ref, bamtools_split_tag Up-to-date https://github.com/pezmaster31/bamtools Sequence Analysis, SAM iuc https://github.com/galaxyproject/tools-iuc/tree/main/tool_collections/bamtools/bamtools_split 2.5.2 bamtools 2.5.2 (4/4) (2/4) (4/4) True False +biotradis bacteria_tradis, tradis_essentiality, tradis_gene_insert_sites Bio-Tradis is a tool suite dedicated to essentiality analyses with TraDis data. Up-to-date https://www.sanger.ac.uk/science/tools/bio-tradis Genome annotation biotradis iuc https://github.com/galaxyproject/tools-iuc/tree/master/tool_collections/biotradis 1.4.5 biotradis 1.4.5 (3/3) (0/3) (0/3) True True +kraken 13938.0 404.0 kraken-filter, kraken-mpa-report, kraken-report, kraken-translate, kraken Kraken is a system for assigning taxonomic labels to short DNAsequences, usually obtained through metagenomic studies. Previous attempts by otherbioinformatics software to accomplish this task have often used sequence alignmentor machine learning techniques that were quite slow, leading to the developmentof less sensitive but much faster abundance estimation programs. Kraken aims toachieve high sensitivity and high speed by utilizing exact alignments of k-mersand a novel classification algorithm. To update http://ccb.jhu.edu/software/kraken/ Metagenomics kraken devteam https://github.com/galaxyproject/tools-iuc/blob/master/tool_collections/kraken/ kraken 1.1.1 (5/5) (5/5) (5/5) True True +kraken2 185308.0 2367.0 kraken2 Kraken2 for taxonomic designation. kraken2 kraken2 Kraken 2 is the newest version of Kraken, a taxonomic classification system using exact k-mer matches to achieve high accuracy and fast classification speeds. This classifier matches each k-mer within a query sequence to the lowest common ancestor (LCA) of all genomes containing the given k-mer. The k-mer assignments inform the classification algorithm. Taxonomic classification Taxonomy, Metagenomics To update http://ccb.jhu.edu/software/kraken/ Metagenomics kraken2 iuc https://github.com/galaxyproject/tools-iuc/blob/master/tool_collections/kraken2/kraken2/ 2.1.1 kraken2 2.1.3 (1/1) (1/1) (1/1) True True +ThermoRawFileParser thermo_raw_file_converter Thermo RAW file converter To update https://github.com/compomics/ThermoRawFileParser Proteomics thermo_raw_file_converter galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/ThermoRawFileParser 1.3.4 thermorawfileparser 1.4.3 (0/1) (1/1) (1/1) True False +bed_to_protein_map 385.0 49.0 bed_to_protein_map Converts a BED file to a tabular list of exon locations To update Proteomics bed_to_protein_map galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/bed_to_protein_map 0.2.0 python (1/1) (1/1) (1/1) True False +blast_plus_remote_blastp blast_plus_remote_blastp NCBI BLAST+ with -remote option To update https://blast.ncbi.nlm.nih.gov/ Sequence Analysis blast_plus_remote_blastp galaxyp https://github.com/peterjc/galaxy_blast/tree/master/tools/ncbi_blast_plus 2.6.0 blast 2.15.0 (0/1) (0/1) (0/1) True False +bumbershoot idpqonvertEmbedder, idpassemble, idpqonvert, idpquery, myrimatch To update http://proteowizard.sourceforge.net/ Proteomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/bumbershoot 3.0.21142 bumbershoot 3_0_21142_0e4f4a4 (0/5) (0/5) (5/5) True False +calisp calisp Calgary approach to isotopes in proteomics Up-to-date https://github.com/kinestetika/Calisp/ Proteomics calisp galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/calisp 3.0.13 calisp 3.0.13 (0/1) (0/1) (1/1) True False +cardinal cardinal_classification, cardinal_colocalization, cardinal_combine, cardinal_data_exporter, cardinal_filtering, cardinal_mz_images, cardinal_preprocessing, cardinal_quality_report, cardinal_segmentations, cardinal_single_ion_segmentation, cardinal_spectra_plots Statistical and computational tools for analyzing mass spectrometry imaging datasets To update http://cardinalmsi.org Proteomics, Metabolomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/cardinal 2.10.0 bioconductor-cardinal 3.4.3 (0/11) (9/11) (11/11) True False +dbbuilder 4758.0 161.0 dbbuilder Protein Database Downloader To update https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/dbbuilder Proteomics dbbuilder galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/dbbuilder 0.3.4 wget (0/1) (1/1) (1/1) True False +decoyfasta 104.0 15.0 Galaxy tool wrapper for the transproteomic pipeline decoyFASTA tool. To update Proteomics decoyfasta galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/decoyfasta (0/1) (0/1) (0/1) True False +dia_umpire 33.0 2.0 dia_umpire_se DIA-Umpire analysis for data independent acquisition (DIA) mass spectrometry-based proteomics To update http://diaumpire.sourceforge.net/ Proteomics dia_umpire galaxyp https://github.com/galaxyproject/tools-iuc/tree/master/tools/dia_umpire 2.1.3 dia_umpire 2.1.6 (0/1) (1/1) (1/1) True False +dialignr 40.0 1.0 dialignr DIAlignR is an R package for retention time alignment of targeted mass spectrometric data, including DIA and SWATH-MS data. This tool works with MS2 chromatograms directly and uses dynamic programming for alignment of raw chromatographic traces. DIAlignR uses a hybrid approach of global (feature-based) and local (raw data-based) alignment to establish correspondence between peaks. To update https://github.com/shubham1637/DIAlignR Proteomics dialignr galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/dialignr 1.2.0 bioconductor-dialignr 2.10.0 (0/1) (0/1) (1/1) True False +diann 15.0 3.0 diann DiaNN (DIA-based Neural Networks) is a software for DIA/SWATH data processing. To update https://github.com/vdemichev/DiaNN Proteomics diann galaxyp https://github.com/vdemichev/DiaNN 1.8.1 (0/1) (1/1) (1/1) True False +diapysef 245.0 11.0 diapysef diapysef is a convenience package for working with DIA-PASEF data To update https://pypi.org/project/diapysef/ Proteomics diapysef galaxyp https://github.com/galaxyproject/tools-iuc/tree/master/tools/diapysef 0.3.5.0 diapysef 1.0.10 (0/1) (1/1) (1/1) True False +diffacto 7.0 5.0 diffacto Diffacto comparative protein abundance estimation Up-to-date https://github.com/statisticalbiotechnology/diffacto Proteomics diffacto galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/diffacto 1.0.6 diffacto 1.0.6 (0/1) (0/1) (1/1) True False +data_manager_eggnog_mapper 9.0 2.0 downloads eggnog data for eggnog-mapper To update Proteomics data_manager_eggnog_mapper galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/eggnog_mapper/eggnog_mapper_data_manager (0/1) (0/1) (0/1) True False +data_manager_eggnog_mapper_abspath 1.0 download eggnog data for eggnog-mapper To update Proteomics data_manager_eggnog_mapper_abspath galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/eggnog_mapper/data_manager_eggnog_mapper_abspath (0/1) (0/1) (0/1) True False +eggnog_mapper 30565.0 510.0 eggnog_mapper, eggnog_mapper_annotate, eggnog_mapper_search eggnog-mapper fast functional annotation of novel sequences eggnog-mapper-v2 eggNOG-mapper v2 EggNOG-mapper is a tool for fast functional annotation of novel sequences. It uses precomputed orthologous groups and phylogenies from the eggNOG database (http://eggnog5.embl.de) to transfer functional information from fine-grained orthologs only. Homology-based gene prediction, Genome annotation, Fold recognition, Information extraction, Query and retrieval Metagenomics, Phylogeny, Transcriptomics, Workflows, Sequence analysis To update Proteomics eggnog_mapper galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/eggnog_mapper/eggnog_mapper 2.1.8 eggnog-mapper 2.1.12 (1/3) (3/3) (3/3) True True +encyclopedia encyclopedia_encyclopedia, encyclopedia_fasta_to_prosit_csv, encyclopedia_library_to_blib, encyclopedia_prosit_csv_to_library, encyclopedia_quantify, encyclopedia_searchtolib, encyclopedia_walnut Mass Spec Data-Independent Acquisition (DIA) MS/MS analysis To update https://bitbucket.org/searleb/encyclopedia/wiki/Home Proteomics encyclopedia galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/encyclopedia/tools/encyclopedia 1.12.34 encyclopedia 2.12.30 (2/7) (4/7) (7/7) True False +fastg2protlib 28.0 1.0 fastg2protlib-peptides, fastg2protlib-validate Generate FASTA from FASTG To update https://github.com/galaxyproteomics/fastg2protlib.git Proteomics fastg2protlib galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/fastg2protlib 1.0.2 (0/2) (0/2) (2/2) True False +feature_alignment 18.0 1.0 feature_alignment TRIC integrates information from all available runs via a graph-based alignment strategy Up-to-date Proteomics feature_alignment galaxyp https://github.com/msproteomicstools/msproteomicstools/blob/master/TRIC-README.md 0.11.0 msproteomicstools 0.11.0 (0/1) (0/1) (1/1) True False +filter_by_fasta_ids 26274.0 426.0 filter_by_fasta_ids Filter FASTA on the headers and/or the sequences To update Fasta Manipulation, Proteomics filter_by_fasta_ids galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/filter_by_fasta_ids 2.3 python (1/1) (1/1) (1/1) True False +flashlfq 645.0 17.0 flashlfq FlashLFQ mass-spectrometry proteomics label-free quantification To update https://github.com/smith-chem-wisc/FlashLFQ Proteomics flashlfq galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/flashlfq 1.0.3.1 flashlfq 1.2.6 (0/1) (1/1) (1/1) True False +hardklor 111.0 2.0 hardklor, kronik Hardklör To update Proteomics hardklor galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/hardklor 2.30.1+galaxy1 hardklor 2.3.2 (0/2) (0/2) (2/2) True False +idconvert 122.0 3.0 idconvert Convert mass spectrometry identification files on linux or MacOSX To update Proteomics idconvert galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msconvert proteowizard 3_0_9992 (0/1) (0/1) (1/1) True False +lfq_protein_quant 111.0 3.0 lfq_protein_quant Enable protein summarisation and quantitation To update https://github.com/compomics/LFQ_galaxy_p Proteomics lfq_protein_quant galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/lfq_protein_quant 1.0 bioconductor-msnbase 2.28.1 (0/1) (0/1) (1/1) True False +maldiquant maldi_quant_peak_detection, maldi_quant_preprocessing MALDIquant provides a complete analysis pipeline for MALDI-TOF and other 2D mass spectrometry data. To update http://strimmerlab.org/software/maldiquant/ Proteomics MALDIquant galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/MALDIquant 1.22.0 r-base (0/2) (2/2) (2/2) True False +map_peptides_to_bed 41.0 1.0 map_peptides_to_bed Map peptides to a reference genome for display by a genome browser To update Proteomics map_peptides_to_bed galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/map_peptides_to_bed 0.2 biopython 1.70 (0/1) (0/1) (1/1) True False +maxquant 5804.0 407.0 maxquant, maxquant_mqpar wrapper for MaxQuant Up-to-date https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/maxquant Proteomics maxquant galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/maxquant 2.0.3.0 maxquant 2.0.3.0 (2/2) (2/2) (2/2) True False +meta_proteome_analyzer 123.0 10.0 meta_proteome_analyzer MetaProteomeAnalyzer Up-to-date https://github.com/compomics/meta-proteome-analyzer/ Proteomics meta_proteome_analyzer galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/meta_proteome_analyzer 2.0.0 mpa-portable 2.0.0 (0/1) (0/1) (1/1) True False +metagene_annotator 636.0 115.0 metagene_annotator MetaGeneAnnotator gene-finding program for prokaryote and phage To update Sequence Analysis metagene_annotator galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/metagene_annotator 1.0.0 metagene_annotator 1.0 (0/1) (0/1) (1/1) True True +metanovo 4181.0 15.0 metanovo Produce targeted databases for mass spectrometry analysis. Up-to-date https://github.com/uct-cbio/proteomics-pipelines Proteomics metanovo galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/metanovo 1.9.4 metanovo 1.9.4 (0/1) (0/1) (1/1) True False +metaquantome metaquantome_db, metaquantome_expand, metaquantome_filter, metaquantome_sample, metaquantome_stat, metaquantome_viz quantitative analysis of microbiome taxonomy and function Up-to-date https://github.com/galaxyproteomics/metaquantome/ Proteomics metaquantome galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/metaquantome 2.0.2 metaquantome 2.0.2 (0/6) (6/6) (6/6) True False +moFF proteomics_moff moFF (a modest Feature Finder) extracts MS1 intensities from RAW and mzML spectrum files. Up-to-date https://github.com/compomics/moFF Proteomics proteomics_moff galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/moFF 2.0.3 moff 2.0.3 (0/1) (1/1) (1/1) True False +morpheus 140.0 4.0 morpheus Morpheus MS Search Application To update Proteomics morpheus galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/morpheus 2.255.0 morpheus 287 (0/1) (1/1) (1/1) True False +mqppep mqppep_anova, mqppep_preproc MaxQuant Phosphoproteomic Enrichment Pipeline - Preprocessing and ANOVA To update https://github.com/galaxyproteomics/tools-galaxyp/ Proteomics mqppep galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/mqppep 0.1.19 bioconductor-preprocesscore 1.64.0 (0/2) (0/2) (2/2) True False +msconvert 20406.0 190.0 msconvert msconvert Convert and/or filter mass spectrometry files (including vendor formats) using the official Docker container To update Proteomics msconvert galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msconvert 3.0.20287 (1/1) (1/1) (1/1) True False +msgfplus 507.0 5.0 msgfplus MSGF+ To update Proteomics msgfplus galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msgfplus 0.5 msgf_plus 2023.01.1202 (0/1) (0/1) (1/1) True False +msms_extractor 110.0 1.0 msms_extractor Extract MS/MS scans from the mzML file(s) based on PSM report. To update Proteomics msms_extractor galaxyp 1.0.0 proteowizard 3_0_9992 (0/1) (0/1) (1/1) True False +msstats 2036.0 144.0 msstats MSstats tool for analyzing mass spectrometry proteomic datasets To update https://github.com/MeenaChoi/MSstats Proteomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msstats 4.0.0 bioconductor-msstats 4.10.0 (1/1) (1/1) (1/1) True False +msstatstmt 726.0 71.0 msstatstmt MSstatsTMT protein significance analysis in shotgun mass spectrometry-based proteomic experiments with tandem mass tag (TMT) labeling To update http://msstats.org/msstatstmt/ Proteomics msstatstmt galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msstatstmt 2.0.0 bioconductor-msstatstmt 2.10.0 (0/1) (1/1) (1/1) True False +mt2mq 270.0 19.0 mt2mq Tool to prepare metatranscriptomic outputs from ASaiM for Metaquantome To update Proteomics mt2mq galaxyp 1.1.0 r-tidyverse (0/1) (0/1) (1/1) True False +mz_to_sqlite 844.0 33.0 mz_to_sqlite Creates a SQLite database for proteomics data To update Proteomics mz_to_sqlite galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/mz_to_sqlite 2.1.1+galaxy0 mztosqlite 2.1.1 (1/1) (1/1) (1/1) True False +openms AccurateMassSearch, AssayGeneratorMetabo, BaselineFilter, CVInspector, ClusterMassTraces, ClusterMassTracesByPrecursor, CometAdapter, CompNovo, CompNovoCID, ConsensusID, ConsensusMapNormalizer, CruxAdapter, DTAExtractor, DatabaseFilter, DatabaseSuitability, DeMeanderize, Decharger, DecoyDatabase, Digestor, DigestorMotif, EICExtractor, ERPairFinder, Epifany, ExternalCalibration, FFEval, FalseDiscoveryRate, FeatureFinderCentroided, FeatureFinderIdentification, FeatureFinderIsotopeWavelet, FeatureFinderMRM, FeatureFinderMetabo, FeatureFinderMetaboIdent, FeatureFinderMultiplex, FeatureLinkerLabeled, FeatureLinkerUnlabeled, FeatureLinkerUnlabeledKD, FeatureLinkerUnlabeledQT, FidoAdapter, FileConverter, FileFilter, FileInfo, FileMerger, FuzzyDiff, GNPSExport, HighResPrecursorMassCorrector, IDConflictResolver, IDExtractor, IDFileConverter, IDFilter, IDMapper, IDMassAccuracy, IDMerger, IDPosteriorErrorProbability, IDRTCalibration, IDRipper, IDScoreSwitcher, IDSplitter, InternalCalibration, IsobaricAnalyzer, LabeledEval, LuciphorAdapter, MRMMapper, MRMPairFinder, MRMTransitionGroupPicker, MSFraggerAdapter, MSGFPlusAdapter, MSSimulator, MSstatsConverter, MaRaClusterAdapter, MapAlignerIdentification, MapAlignerPoseClustering, MapAlignerSpectrum, MapAlignerTreeGuided, MapNormalizer, MapRTTransformer, MapStatistics, MascotAdapter, MascotAdapterOnline, MassCalculator, MassTraceExtractor, MetaProSIP, MetaboliteAdductDecharger, MetaboliteSpectralMatcher, MultiplexResolver, MyriMatchAdapter, MzMLSplitter, MzTabExporter, NoiseFilterGaussian, NoiseFilterSGolay, NovorAdapter, NucleicAcidSearchEngine, OMSSAAdapter, OpenMSDatabasesInfo, OpenPepXL, OpenPepXLLF, OpenSwathAnalyzer, OpenSwathAssayGenerator, OpenSwathChromatogramExtractor, OpenSwathConfidenceScoring, OpenSwathDIAPreScoring, OpenSwathDecoyGenerator, OpenSwathFeatureXMLToTSV, OpenSwathFileSplitter, OpenSwathMzMLFileCacher, OpenSwathRTNormalizer, OpenSwathRewriteToFeatureXML, OpenSwathWorkflow, PSMFeatureExtractor, PTModel, PeakPickerHiRes, PeakPickerIterative, PeakPickerWavelet, PepNovoAdapter, PeptideIndexer, PercolatorAdapter, PhosphoScoring, PrecursorIonSelector, PrecursorMassCorrector, ProteinInference, ProteinQuantifier, ProteinResolver, QCCalculator, QCEmbedder, QCExporter, QCExtractor, QCImporter, QCMerger, QCShrinker, QualityControl, RNADigestor, RNAMassCalculator, RNPxlSearch, RNPxlXICFilter, RTEvaluation, RTModel, SeedListGenerator, SemanticValidator, SequenceCoverageCalculator, SimpleSearchEngine, SiriusAdapter, SpecLibCreator, SpecLibSearcher, SpectraFilterBernNorm, SpectraFilterMarkerMower, SpectraFilterNLargest, SpectraFilterNormalizer, SpectraFilterParentPeakMower, SpectraFilterScaler, SpectraFilterSqrtMower, SpectraFilterThresholdMower, SpectraFilterWindowMower, SpectraMerger, SpectraSTSearchAdapter, StaticModification, SvmTheoreticalSpectrumGeneratorTrainer, TICCalculator, TOFCalibration, TargetedFileConverter, TextExporter, TransformationEvaluation, TriqlerConverter, XFDR, XMLValidator, XTandemAdapter OpenMS Suite for LC/MS data management and analyses To update https://www.openms.de/ Proteomics openms galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/openms 2.8 openms 3.1.0 (1/164) (35/164) (160/164) True False +pathwaymatcher reactome_pathwaymatcher Reactome Pathway Matcher To update https://github.com/LuisFranciscoHS/PathwayMatcher Proteomics reactome_pathwaymatcher galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pathwaymatcher pathwaymatcher 1.9.1 (0/1) (0/1) (1/1) True False +pep_pointer 498.0 9.0 pep_pointer PepPointer categorizes peptides by their genomic coordinates. To update Genomic Interval Operations, Proteomics pep_pointer galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pep_pointer 0.1.3+galaxy1 python (1/1) (1/1) (1/1) True False +pepquery 4862.0 23.0 pepquery A peptide-centric MS search engine for novel peptide identification and validation. To update https://pepquery.org Proteomics pepquery galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pepquery 1.6.2 pepquery 2.0.2 (0/1) (0/1) (1/1) True False +pepquery2 707.0 10.0 pepquery2, pepquery2_index, pepquery2_show_sets PepQuery2 peptide-centric MS search for peptide identification and validation Up-to-date https://pepquery.org Proteomics pepquery2 galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pepquery2 2.0.2 pepquery 2.0.2 (0/3) (0/3) (3/3) True False +peptide_genomic_coordinate 468.0 9.0 peptide_genomic_coordinate Gets genomic coordinate of peptides based on the information in mzsqlite and genomic mapping sqlite files To update Proteomics peptide_genomic_coordinate galaxyp 1.0.0 python (1/1) (1/1) (1/1) True False +peptideshaker 17477.0 485.0 fasta_cli, ident_params, peptide_shaker, search_gui PeptideShaker and SearchGUI To update http://compomics.github.io Proteomics peptideshaker galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/peptideshaker searchgui 4.3.6 (4/4) (4/4) (4/4) True False +pepxml_to_xls Convert PepXML to Tabular To update Proteomics pepxml_to_xls galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pepxml_to_xls (0/1) (0/1) (0/1) True False +percolator 368.0 5.0 batched_set_list_creator, percolator, percolator_input_converters, pout2mzid Percolator Up-to-date Proteomics percolator galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/percolator 3.5 percolator 3.5 (0/4) (4/4) (4/4) True False +pi_db_tools calc_delta_pi, pi_db_split, pi_dbspec_align HiRIEF tools To update Proteomics hirieftools galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/pi_db_tools 1.3 python (0/3) (0/3) (0/3) True False +pmd_fdr pmd_fdr Calculate Precursor Mass Discrepancy (PMD) for MS/MS To update https://github.com/slhubler/PMD-FDR-for-Galaxy-P Proteomics pmd_fdr galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pmd_fdr 1.4.0 r-base (0/1) (0/1) (0/1) True False +custom_pro_db 1652.0 57.0 custom_pro_db CustomProDB To update https://bioconductor.org/packages/release/bioc/html/customProDB.html Proteomics custom_pro_db galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/bumbershoot/custom_pro_db 1.22.0 bioconductor-rgalaxy 1.37.1 (1/1) (1/1) (1/1) True False +custom_pro_db_annotation_data_manager CustomProDB Annotation To update https://bioconductor.org/packages/release/bioc/html/customProDB.html Proteomics custom_pro_db_annotation_data_manager galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/bumbershoot/custom_pro_db (0/1) (0/1) (0/1) True False +psm2sam PSMtoSAM PSM to SAM To update https://bioconductor.org/packages/release/bioc/html/proBAMr.html Proteomics psm_to_sam galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tools/bumbershoot/psm2sam 1.3.2.1 r-base (0/1) (0/1) (0/1) True False +translate_bed 643.0 49.0 translate_bed Translate BED transcript CDS or cDNA in 3 frames To update http://rest.ensembl.org/ Proteomics translate_bed galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteogenomics/translate_bed 0.1.0 (1/1) (1/1) (1/1) True False +proteomiqon_joinquantpepionswithproteins 366.0 4.0 proteomiqon_joinquantpepionswithproteins The tool JoinQuantPepIonsWithProteins combines results from ProteinInference and PSMBasedQuantification. To update https://csbiology.github.io/ProteomIQon/tools/JoinQuantPepIonsWithProteins.html Proteomics proteomiqon_joinquantpepionswithproteins galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_joinquantpepionswithproteins 0.0.1 proteomiqon-joinquantpepionswithproteins 0.0.2 (0/1) (0/1) (1/1) True False +proteomiqon_labeledproteinquantification 14.0 5.0 proteomiqon_labeledproteinquantification The tool LabeledProteinQuantification estimates protein abundances using quantified peptide ions. To update https://csbiology.github.io/ProteomIQon/tools/LabeledProteinQuantification.html Proteomics proteomiqon_labeledproteinquantification galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_labeledproteinquantification 0.0.1 proteomiqon-labeledproteinquantification 0.0.3 (0/1) (0/1) (1/1) True False +proteomiqon_labelfreeproteinquantification 6.0 3.0 proteomiqon_labelfreeproteinquantification The tool LabelFreeProteinQuantification estimates protein abundances using quantified peptide ions. To update https://csbiology.github.io/ProteomIQon/tools/LabelfreeProteinQuantification.html Proteomics proteomiqon_labelfreeproteinquantification galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_labelfreeproteinquantification 0.0.1 proteomiqon-labelfreeproteinquantification 0.0.3 (0/1) (0/1) (1/1) True False +proteomiqon_mzmltomzlite 721.0 5.0 proteomiqon_mzmltomzlite The tool MzMLToMzLite allows to convert mzML files to mzLite files. Up-to-date https://csbiology.github.io/ProteomIQon/tools/MzMLToMzLite.html Proteomics proteomiqon_mzmltomzlite galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomIQon_MzMLToMzLite 0.0.8 proteomiqon-mzmltomzlite 0.0.8 (0/1) (0/1) (1/1) True False +proteomiqon_peptidedb 96.0 6.0 proteomiqon_peptidedb The tool ProteomIQon PeptideDB creates a peptide database in the SQLite format. Up-to-date https://csbiology.github.io/ProteomIQon/tools/PeptideDB.html Proteomics proteomiqon_peptidedb galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_peptidedb 0.0.7 proteomiqon-peptidedb 0.0.7 (0/1) (0/1) (1/1) True False +proteomiqon_peptidespectrummatching 686.0 4.0 proteomiqon_peptidespectrummatching Given raw an MS run in the mzLite format, this tool iterates across all MS/MS scans, determines precursor charge states and possible peptide spectrum matches using reimplementations of SEQUEST,Andromeda and XTandem. Up-to-date https://csbiology.github.io/ProteomIQon/tools/PeptideSpectrumMatching.html Proteomics proteomiqon_peptidespectrummatching galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_peptidespectrummatching 0.0.7 proteomiqon-peptidespectrummatching 0.0.7 (0/1) (0/1) (1/1) True False +proteomiqon_proteininference 89.0 4.0 proteomiqon_proteininference MS-based shotgun proteomics estimates protein abundances using a proxy: peptides. The process of 'Protein Inference' is concerned with the mapping of identified peptides to the proteins they putatively originated from. Up-to-date https://csbiology.github.io/ProteomIQon/tools/ProteinInference.html Proteomics proteomiqon_proteininference galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_proteininference 0.0.7 proteomiqon-proteininference 0.0.7 (0/1) (0/1) (1/1) True False +proteomiqon_psmbasedquantification 604.0 4.0 proteomiqon_psmbasedquantification The PSMBasedQuantification tool was designed to allow label-free quantification as well as quantification of full metabolic labeled samples. To update https://csbiology.github.io/ProteomIQon/tools/PSMBasedQuantification.html Proteomics proteomiqon_psmbasedquantification galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_psmbasedquantification 0.0.8 proteomiqon-psmbasedquantification 0.0.9 (0/1) (0/1) (1/1) True False +proteomiqon_psmstatistics 694.0 4.0 proteomiqon_psmstatistics The PSMStatistics tool utilizes semi supervised machine learning techniques to integrate search engine scores as well as the mentioned quality scores into one single consensus score. Up-to-date https://csbiology.github.io/ProteomIQon/tools/PSMStatistics.html Proteomics proteomiqon_psmstatistics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/proteomiqon_psmstatistics 0.0.8 proteomiqon-psmstatistics 0.0.8 (0/1) (0/1) (1/1) True False +proteore_venn_diagram 15.0 proteore_venn_diagram ProteoRE JVenn Diagram To update Proteomics proteore_venn_diagram galaxyp 2021.06.08 python (0/1) (0/1) (0/1) True False +psm_validation 20.0 psmvalidator Validate PSM from Ion Fragmentation To update https://github.com/galaxyproteomics/psm_fragments.git Proteomics psm_validation galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/psm_validation 1.0.3 (0/1) (0/1) (1/1) True False +pyprophet pyprophet_export, pyprophet_merge, pyprophet_peptide, pyprophet_protein, pyprophet_score, pyprophet_subsample Semi-supervised learning and scoring of OpenSWATH results. To update https://github.com/PyProphet/pyprophet Proteomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pyprophet 2.1.4 pyprophet 2.2.5 (0/6) (4/6) (6/6) True False +pyteomics mztab2tsv Tools using the pyteomics library pyteomics Pyteomics Framework for proteomics data analysis, supporting mzML, MGF, pepXML and more. Protein identification Proteomics, Proteomics experiment To update https://pyteomics.readthedocs.io/en/latest/ Proteomics, Metabolomics pyteomics galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/pyteomics 4.4.1 pyteomics 4.7.1 (0/1) (0/1) (1/1) True False +quantp 230.0 6.0 quantp Correlation between protein and transcript abundance To update Proteomics quantp galaxyp 1.1.2 r-data.table 1.11.6 (0/1) (0/1) (1/1) True False +quantwiz_iq 32.0 1.0 quantwiz_iq Isobaric Quantitation using QuantWiz-IQ Up-to-date https://sourceforge.net/projects/quantwiz/ Proteomics quantwiz_iq galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/quantwiz_iq 2.0 quantwiz-iq 2.0 (0/1) (0/1) (1/1) True False +rawtools 175.0 14.0 rawtools Raw Tools To update https://github.com/kevinkovalchik/RawTools Proteomics rawtools galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/rawtools rawtools 2.0.4 (0/1) (1/1) (1/1) True False +sixgill 293.0 24.0 sixgill_build, sixgill_filter, sixgill_makefasta, sixgill_merge Six-frame Genome-Inferred Libraries for LC-MS/MS Up-to-date Proteomics, MetaProteomics sixgill galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/sixgill 0.2.4 sixgill 0.2.4 (0/4) (0/4) (4/4) True False +spectrast2spectrast_irt gp_spectrast2spectrast_irt Filter from spectraST files to swath input files To update Proteomics spectrast2spectrast_irt galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/spectrast2spectrast_irt 0.1.0 msproteomicstools 0.11.0 (0/1) (0/1) (0/1) True False +spectrast2tsv gp_spectrast2tsv Filter from spectraST files to swath input files To update Proteomics spectrast2tsv galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/spectrast2tsv 0.1.0 msproteomicstools 0.11.0 (0/1) (0/1) (0/1) True False +translate_bed_sequences 57.0 6.0 translate_bed_sequences Perform 3 frame translation of BED file augmented with a sequence column To update Proteomics translate_bed_sequences galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/translate_bed_sequences 0.2.0 biopython 1.70 (0/1) (0/1) (1/1) True False +unipept 5005.0 115.0 unipept Unipept retrieves metaproteomics information To update https://github.com/galaxyproteomics/tools-galaxyp Proteomics unipept galaxyp https://unipept.ugent.be/apidocs 4.5.1 python (1/1) (1/1) (1/1) True False +uniprotxml_downloader 1360.0 79.0 uniprotxml_downloader Download UniProt proteome in XML or fasta format To update Proteomics uniprotxml_downloader galaxyp https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/uniprotxml_downloader 2.4.0 requests (0/1) (1/1) (1/1) True False +validate_fasta_database 86.0 25.0 validate_fasta_database runs Compomics database identification tool on any FASTA database, and separates valid and invalid entries based on a series of checks. To update Fasta Manipulation, Proteomics validate_fasta_database galaxyp 0.1.5 validate-fasta-database 1.0 (0/1) (0/1) (1/1) True False +bamparse bamparse Generates hit count lists from bam alignments. To update http://artbio.fr RNA, Transcriptomics bamparse artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/bamparse 4.1.1 pysam 0.22.0 (0/1) (0/1) (0/1) True False +blast_to_scaffold blast2scaffold Generate DNA scaffold from blastn or tblastx alignments of Contigs To update http://artbio.fr RNA, Sequence Analysis, Assembly blast_to_scaffold artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/blast_to_scaffold 1.1.0 python (0/1) (0/1) (0/1) True False +blastparser_and_hits BlastParser_and_hits Parse blast outputs and compile hits To update http://artbio.fr Assembly, RNA blastparser_and_hits artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/blastparser_and_hits 2.7.1 python (0/1) (0/1) (0/1) True False +blastx_to_scaffold blastx2scaffold Generate DNA scaffold from blastx alignment of Contigs To update http://artbio.fr RNA, Sequence Analysis, Assembly blastx_to_scaffold artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/blastx_to_scaffold 1.1.1 python (0/1) (0/1) (0/1) True False +cap3 7766.0 101.0 cap3 cap3 wrapper To update http://artbio.fr Assembly cap3 artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/cap3 2.0.1 cap3 10.2011 (0/1) (1/1) (1/1) True False +deseq2_normalization deseq2_normalization Normalizes gene hitlists To update http://artbio.fr RNA, Transcriptomics, Sequence Analysis, Statistics deseq2_normalization artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/deseq2_normalization 1.40.2+galaxy0 bioconductor-deseq2 1.42.0 (0/1) (0/1) (0/1) True False +ez_histograms ez_histograms ggplot2 histograms and density plots To update https://github.com/tidyverse/ggplot2 Visualization, Statistics ez_histograms artbio https://github.com/artbio/tools-artbio/tree/main/tools/ez_histograms 3.4.4 r-ggplot2 2.2.1 (0/1) (0/1) (0/1) False +fisher_test fishertest Fisher's exact test on two-column hit lists. To update http://artbio.fr RNA, Statistics fishertest artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/fisher_test 2.32.0+galaxy0 bioconductor-qvalue 2.34.0 (0/1) (0/1) (0/1) True False +gsc_high_dimensions_visualisation high_dimensions_visualisation Generates PCA, t-SNE and HCPC visualisation To update http://artbio.fr Transcriptomics, Visualization gsc_high_dimensions_visualisation artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/gsc_high_dimension_visualization 4.3+galaxy0 r-optparse 1.3.2 (0/1) (0/1) (0/1) True False +guppy guppy-basecaller A wrapper for the guppy basecaller tool from Oxford Nanopore Technologies To update http://artbio.fr Nanopore guppy_basecaller artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/guppy 0.2.2 (0/1) (0/1) (0/1) True False +high_dim_heatmap high_dim_heatmap gplot heatmap.2 function adapted for plotting large heatmaps To update https://github.com/cran/gplots Visualization high_dim_heatmap artbio https://github.com/artbio/tools-artbio/tree/main/tools/high_dim_heatmap 3.1.3+galaxy0 r-gplots 2.17.0 (0/1) (0/1) (0/1) True False +mapping_quality_stats mapqstatistics Collects and shows the distribution of MAPQ values in a BAM alignment file To update http://artbio.fr Sequence Analysis, Statistics mapping_quality_stats artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/mapping_quality_stats 0.22.0 r-optparse 1.3.2 (0/1) (0/1) (0/1) True False +mircounts mircounts Generates miRNA count lists from read alignments to mirBase. To update http://artbio.fr RNA, Transcriptomics mircounts artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/mircounts 1.6 tar (0/1) (1/1) (0/1) True False +oases oasesoptimiserv Short read assembler To update http://artbio.fr Assembly, RNA oases artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/oases 1.4.0 oases 0.2.09 (0/1) (0/1) (0/1) True False +probecoverage probecoverage computes and plots read coverage of genomic regions by sequencing datasets Up-to-date http://artbio.fr Sequence Analysis, Genomic Interval Operations, Graphics, Statistics probecoverage artbio https://github.com/ARTbio/tools-artbio/tree/main/tools/probecoverage 0.22.0 pysam 0.22.0 (0/1) (0/1) (0/1) True False +rsem 2273.0 199.0 extract_transcript_to_gene_map_from_trinity, purgegtffrommultichromgenes, rsembowtie2, rsembowtie transcript quantification from RNA-Seq data To update https://github.com/deweylab/RSEM Transcriptomics, RNA rsem artbio https://github.com/artbio/tools-artbio/tree/master/tools/rsem rsem 1.3.3 (0/4) (0/4) (1/4) True False +sashimi_plot sashimi_plot Generates a sashimi plot from bam files. To update http://artbio.fr RNA, Transcriptomics, Graphics, Visualization sashimi_plot artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/sashimi_plot 0.1.1 python (0/1) (0/1) (0/1) True False +small_rna_clusters small_rna_clusters clusters small rna reads in alignment BAM files To update http://artbio.fr RNA, SAM, Graphics, Next Gen Mappers small_rna_clusters artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/small_rna_clusters 1.3.0 pysam 0.22.0 (0/1) (0/1) (0/1) True False +small_rna_maps small_rna_maps Generates small read maps from alignment BAM files To update http://artbio.fr RNA, SAM, Graphics, Next Gen Mappers small_rna_maps artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/small_rna_maps 3.1.1 numpy (0/1) (0/1) (0/1) True False +small_rna_signatures overlapping_reads, signature Computes the tendency of small RNAs to overlap with each other. To update http://artbio.fr RNA small_rna_signatures artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/small_rna_signatures 3.4.2 pysam 0.22.0 (0/2) (0/2) (0/2) True False +sr_bowtie bowtieForSmallRNA bowtie wrapper tool to align small RNA sequencing reads To update http://artbio.fr RNA, Next Gen Mappers sr_bowtie artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/sr_bowtie 2.3.0 bowtie 1.3.1 (0/1) (0/1) (0/1) True False +sr_bowtie_dataset_annotation sr_bowtie_dataset_annotation Maps iteratively small RNA sequencing datasets to reference sequences. To update http://artbio.fr RNA sr_bowtie_dataset_annotation artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/sr_bowtie_dataset_annotation 2.8 bowtie 1.3.1 (0/1) (0/1) (0/1) True False +tarfast5 tarfast5 produces a tar.gz archive of fast5 sequence files To update http://artbio.fr Nanopore tarfast5 artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/tarfast5 0.6.1 pigz (0/1) (0/1) (0/1) True False +xpore xpore_dataprep, xpore_diffmod Identification and quantification of differential RNA modifications from direct RNA sequencing To update https://github.com/GoekeLab/xpore Nanopore xpore artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/xpore 2.1+galaxy0 xpore 2.1 (0/2) (0/2) (0/2) True False +yac_clipper yac Clips 3' adapters for small RNA sequencing reads. To update http://artbio.fr RNA, Fastq Manipulation yac_clipper artbio https://github.com/ARTbio/tools-artbio/tree/master/tools/yac_clipper 2.5.1 python (0/1) (0/1) (0/1) True False +EMLassemblyline eal_table_template, eal_templates, eml2eal, entities_template, geo_cov_template, makeeml, raster_template, taxo_cov_template, vector_template Tools using EML Assembly Line R package to generate EML metadata from template metadata files and vice versa To update https://github.com/EDIorg/EMLassemblyline Ecology emlassemblyline ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/EMLassemblyline 0.1.1+galaxy0 r-emlassemblyline (0/9) (0/9) (9/9) True False +Ecoregionalization_workflow ecoregion_brt_analysis, ecoregion_cluster_estimate, ecoregion_clara_cluster, ecoregion_eco_map, ecoregion_taxa_seeker Tools to compute ecoregionalization with BRT model predictions and clustering. To update https://github.com/PaulineSGN/Workflow_Galaxy Ecology ecoregionalization ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/Ecoregionalization_workflow 0.1.0+galaxy0 r-base (0/5) (0/5) (5/5) True False +Geom_mean_workflow Map_shp, Mean_geom, bar_plot Tools to compute The evolution of the total volume of very large trees, standing dead wood and dead wood on the ground on an area and the rate of devolution of the volume of wood favorable to biodiversity by large ecological regions (France). To update https://github.com/PaulineSGN/Galaxy_tool_moyenne_geom Ecology Geometric means (Dead wood) ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/Geom_mean_workflow 0.1.0+galaxy0 r-base (0/3) (0/3) (3/3) False +PAMPA pampa_communitymetrics, pampa_presabs, pampa_glmcomm, pampa_glmsp, pampa_plotglm Tools to compute and analyse biodiversity metrics To update Ecology pampa ecology https://github.com/ColineRoyaux/PAMPA-Galaxy 0.0.2 (0/5) (5/5) (5/5) True True +champ_blocs cb_dissim, cb_ivr, cb_div Compute indicators for turnover boulders fields To update Ecology ecology https://github.com/Marie59/champ_blocs 0.0.0 r-base (0/3) (0/3) (3/3) True False +consensus_from_alignments aligned_to_consensus Tool to compute a consensus sequence from several aligned fasta sequences To update Sequence Analysis consalign ecology https://github.com/ColineRoyaux/Galaxy_tool_projects/tree/main/consensus_from_alignments 1.0.0 r-bioseq (0/1) (0/1) (1/1) True False +data_exploration tool_anonymization, ecology_homogeneity_normality, ecology_beta_diversity, ecology_link_between_var, ecology_presence_abs_abund, ecology_stat_presence_abs Explore data through multiple statistical tools To update Ecology ecology https://github.com/Marie59/Data_explo_tools 0.0.0 r-tangles (0/6) (0/6) (6/6) True False +xarray timeseries_extraction, xarray_coords_info, xarray_mapplot, xarray_metadata_info, xarray_netcdf2netcdf, xarray_select xarray (formerly xray) is an open source project and Python package that makes working withlabelled multi-dimensional arrays simple, efficient, and fun!xarray integrates with Dask to support parallel computations and streaming computation on datasetsthat don’t fit into memory. To update http://xarray.pydata.org Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/data_manipulation/xarray/ 2022.3.0 xarray (5/6) (2/6) (6/6) True False +gdal gdal_gdal_merge, gdal_gdal_translate, gdal_gdaladdo, gdal_gdalbuildvrt, gdal_gdalinfo, gdal_gdalwarp, gdal_ogr2ogr, gdal_ogrinfo Geospatial Data Abstraction Library tools are all dedicated to manipulate raster and vector geospatial data formats. To update https://www.gdal.org Ecology gdal ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/gdal 3.0.0 (0/8) (0/8) (8/8) True False +interpolation interpolation_run_idw_interpolation Run IDW interpolation based on a .csv and .geojson file To update https://github.com/AquaINFRA/galaxy Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/interpolation 1.0 r-getopt (0/1) (0/1) (1/1) False +medenv iabiodiv_smartbiodiv_med_environ Retrieve environmental data from etopo, cmems and woa To update https://github.com/jeremyfix/medenv Ecology, Data Source ecology https://github.com/jeremyfix/medenv 0.0.1 pandas (0/1) (0/1) (1/1) False +obisindicators 45.0 4.0 obisindicators, obis_data Compute biodiveristy indicators for marine data from obis To update https://github.com/Marie59/obisindicators Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/obisindicators 0.0.2 r-base (1/2) (0/2) (2/2) True True +ocean argo_getdata Access, process, visualise oceanographic data for the Earth System To update https://github.com/Marie59/FE-ft-ESG/tree/main/argo Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/ocean 0.1.15 (0/1) (0/1) (1/1) False +regionalgam regionalgam_ab_index, regionalgam_autocor_acf, regionalgam_flight_curve, regionalgam_glmmpql, regionalgam_gls_adjusted, regionalgam_gls, regionalgam_plot_trend To update https://github.com/RetoSchmucki/regionalGAM Ecology ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/regionalgam 1.5 r-mgcv (0/7) (0/7) (7/7) True False +spocc spocc_occ Get species occurences data To update https://cran.r-project.org/web/packages/spocc/index.html Ecology spocc_occ ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/spocc 1.2.2 (0/1) (0/1) (1/1) True False +srs_tools srs_diversity_maps, srs_global_indices, srs_process_data, srs_spectral_indices, srs_pca, srs_preprocess_s2, srs_metadata Compute biodiversity indicators for remote sensing data from Sentinel 2 To update Ecology ecology https://github.com/Marie59/Sentinel_2A/srs_tools 0.0.1 r-base (4/7) (0/7) (7/7) True False +stoc stoceps_filteringsp, stoceps_glm, stoceps_glm_group, stoceps_maketablecarrer, stoceps_trend_indic Tools to analyse STOC data. To update Ecology stoceps ecology https://github.com/Alanamosse/Galaxy-E/tree/stoctool/tools/stoc 0.0.2 (0/5) (0/5) (5/5) True False +vigiechiro vigiechiro_bilanenrichipf, vigiechiro_bilanenrichirp, vigiechiro_idcorrect_2ndlayer, vigiechiro_idvalid Tools created by the vigiechiro team to analyses and identify chiro sounds files. To update https://www.vigienature-ecole.fr/les-observatoires/le-protocole-vigie-chiro Ecology vigiechiro ecology https://github.com/galaxyecology/tools-ecology/tree/master/tools/vigiechiro 0.1.1 (0/4) (0/4) (4/4) True False +climate-stripes climate_stripes Create climate stripes from a tabular input file To update https://www.climate-lab-book.ac.uk/2018/warming-stripes/ Climate Analysis, Visualization climate_stripes climate https://github.com/NordicESMhub/galaxy-tools/tree/master/tools/climate-stripes 1.0.2 python (1/1) (1/1) (1/1) True False +mean-per-zone mean_per_zone Creates a png image showing statistic over areas as defined in the vector file To update https://github.com/NordicESMhub/galaxy-tools/blob/master/tools/mean-per-zone/ Visualization, GIS, Climate Analysis mean_per_zone climate https://github.com/NordicESMhub/galaxy-tools/tree/master/tools/mean-per-zone 0.2.0 python (0/1) (0/1) (1/1) True False +psy-maps psy_maps Visualization of regular geographical data on a map with psyplot To update https://github.com/Chilipp/psy-maps Visualization, Climate Analysis psy_maps climate https://github.com/NordicESMhub/galaxy-tools/tree/master/tools/psy-maps 1.2.1 python (0/1) (0/1) (1/1) True False +droplet-barcode-plot _dropletBarcodePlot Make a cell barcode plot for droplet single-cell RNA-seq QC To update https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary Sequence Analysis droplet_barcode_plot ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/droplet-rank-plot/.shed.yml 1.6.1+galaxy2 scxa-plots 0.0.1 (1/1) (0/1) (1/1) True False +fastq_provider fastq_provider Retrieval and download of FASTQ files from ENA and other repositories such as HCA. To update https://github.com/ebi-gene-expression-group/atlas-fastq-provider Data Source, RNA, Transcriptomics atlas_fastq_provider ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/fastq_provider 0.4.4 atlas-fastq-provider 0.4.7 (0/1) (0/1) (0/1) True False +gtf-2-gene-list _ensembl_gtf2gene_list Utility to extract annotations from Ensembl GTF files. To update https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary Sequence Analysis gtf2gene_list ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/gtf-2-gene-list/.shed.yml 1.52.0+galaxy0 atlas-gene-annotation-manipulation 1.1.0 (1/1) (1/1) (1/1) True False +fastq_utils fastq_filter_n, fastq_trim_poly_at Set of tools for handling fastq files To update https://github.com/nunofonseca/fastq_utils Transcriptomics, RNA fastq_utils ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/qc/fastq_utils 0.25.1+galaxy0 fastq_utils 0.25.2 (0/2) (0/2) (0/2) True False +salmon-kallisto-mtx-to-10x _salmon_kallisto_mtx_to_10x Transforms .mtx matrix and associated labels into a format compatible with tools expecting old-style 10X data To update https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary Sequence Analysis salmon_kallisto_mtx_to_10x ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/salmon-kallisto-mtx-to-10x/.shed.yml 0.0.1+galaxy6 scipy (1/1) (1/1) (1/1) True False +cell-types-analysis ct_build_cell_ontology_dict, ct_check_labels, ct_combine_tool_outputs, ct_downsample_cells, ct_get_consensus_outputs, ct_get_empirical_dist, ct_get_tool_perf_table, ct_get_tool_pvals Tools for analysis of predictions from scRNAseq cell type classification tools, see https://github.com/ebi-gene-expression-group/cell-types-analysis To update Transcriptomics, RNA, Statistics suite_cell_types_analysis ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.1.1 cell-types-analysis 0.1.11 (0/8) (0/8) (6/8) True False +data-hca hca_matrix_downloader Tools for interacting with the Human Cell Atlas resource https://prod.data.humancellatlas.org/explore/projects To update Transcriptomics, Sequence Analysis suite_human_cell_atlas_tools ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ v0.0.4+galaxy0 hca-matrix-downloader 0.0.4 (0/1) (0/1) (1/1) True False +data-scxa retrieve_scxa Tools for interacting with the EMBL-EBI Expression Atlas resource https://www.ebi.ac.uk/gxa/home https://www.ebi.ac.uk/gxa/sc/home To update Transcriptomics, Sequence Analysis suite_ebi_expression_atlas ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ v0.0.2+galaxy2 wget (1/1) (1/1) (1/1) True False +dropletutils 3934.0 126.0 dropletutils_empty_drops, dropletutils_read_10x De-composed DropletUtils functionality tools, based on https://github.com/ebi-gene-expression-group/dropletutils-scripts and DropletUtils 1.0.3 To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_dropletutils ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.0.4 dropletutils-scripts 0.0.5 (2/2) (0/2) (2/2) True False +garnett garnett_check_markers, garnett_classify_cells, garnett_get_feature_genes, garnett_get_std_output, garnett_train_classifier, garnett_transform_markers, update_marker_file De-composed Garnett functionality tools, see https://github.com/ebi-gene-expression-group/garnett-cli and r-garnett 0.2.8 To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_garnett ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 0.2.8 garnett-cli 0.0.5 (0/7) (0/7) (7/7) True False +monocle3 monocle3_create, monocle3_diffExp, monocle3_learnGraph, monocle3_orderCells, monocle3_partition, monocle3_plotCells, monocle3_preprocess, monocle3_reduceDim, monocle3_topmarkers De-composed monocle3 functionality tools, based on https://github.com/ebi-gene-expression-group/monocle-scripts and monocle3 0.1.2. To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_monocle3 ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 0.1.4 monocle3-cli 0.0.9 (9/9) (0/9) (9/9) True False +sc3 sc3_calc_biology, sc3_calc_consens, sc3_calc_dists, sc3_calc_transfs, sc3_estimate_k, sc3_kmeans, sc3_prepare De-composed SC3 functionality tools, based on https://github.com/ebi-gene-expression-group/bioconductor-sc3-scripts and SC3 1.8.0. To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_sc3 ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.8.0 sc3-scripts 0.0.6 (0/7) (0/7) (7/7) True False +scanpy anndata_ops, scanpy_filter_cells, scanpy_filter_genes, scanpy_find_cluster, scanpy_find_markers, scanpy_find_variable_genes, scanpy_integrate_bbknn, scanpy_integrate_combat, scanpy_integrate_harmony, scanpy_integrate_mnn, scanpy_plot_scrublet, scanpy_multiplet_scrublet, scanpy_compute_graph, scanpy_normalise_data, scanpy_parameter_iterator, scanpy_plot_embed, scanpy_plot_trajectory, scanpy_read_10x, scanpy_regress_variable, scanpy_run_diffmap, scanpy_run_dpt, scanpy_run_fdg, scanpy_run_paga, scanpy_run_pca, scanpy_run_tsne, scanpy_run_umap, scanpy_scale_data scanpy-scripts, command-line wrapper scripts around Scanpy. To update https://scanpy.readthedocs.io Transcriptomics, Sequence Analysis, RNA scanpy_scripts ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/tree/develop/tools/tertiary-analysis/scanpy 1.8.1 scanpy-scripts 1.9.301 (17/27) (27/27) (27/27) True False +scater scater_calculate_cpm, scater_calculate_qc_metrics, scater_filter, scater_is_outlier, scater_normalize, scater_read_10x_results De-composed Scater functionality tools, based on https://github.com/ebi-gene-expression-group/bioconductor-scater-scripts and Scater 1.8.4. To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_scater ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.10.0 scater-scripts 0.0.5 (0/6) (1/6) (6/6) True False +scmap scmap_get_std_output, scmap_index_cell, scmap_index_cluster, scmap_preprocess_sce, scmap_scmap_cell, scmap_scmap_cluster, scmap_select_features De-composed scmap functionality tools, based on https://github.com/ebi-gene-expression-group/scmap-cli and scmap 1.6.0. To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_scmap ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.6.3 scmap-cli 0.1.0 (0/7) (0/7) (7/7) True False +scpred scpred_get_feature_space, scpred_get_std_output, scpred_predict_labels, scpred_train_model De-composed scPred functionality tools, see https://github.com/ebi-gene-expression-group/scpred-cli and r-scPred 1.0 To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_scpred ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 1.0.2 scpred-cli 0.1.0 (0/4) (0/4) (4/4) True False +seurat 1543.0 66.0 seurat_convert, seurat_dim_plot, seurat_export_cellbrowser, seurat_filter_cells, seurat_find_clusters, seurat_find_markers, seurat_find_neighbours, seurat_find_variable_genes, seurat_normalise_data, seurat_read10x, seurat_run_pca, seurat_run_tsne, seurat_scale_data De-composed Seurat functionality tools, based on https://github.com/ebi-gene-expression-group/r-seurat-scripts and Seurat 2.3.1 To update Transcriptomics, RNA, Statistics, Sequence Analysis suite_seurat ebi-gxa https://github.com/ebi-gene-expression-group/container-galaxy-sc-tertiary/ 0.3.0 seurat-scripts 4.0.0 (0/13) (0/13) (12/13) True False +mzml_validator mzml_validator mzML Validator checks if mzML file validates against XML Schema Definition of HUPO Proteomics Standard Initiative. To update https://github.com/RECETOX/galaxytools Metabolomics, Proteomics recetox https://github.com/RECETOX/galaxytools/tree/master/tools/mzml_validator 0.1.0+galaxy2 lxml (0/1) (0/1) (0/1) True False +consolidate_vcfs consolidate_vcfs Combines freebayes and mpileup files for use by vcf2snvalignment Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis consolidate_vcfs nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False +filter_density filterdensity Filter out position based on distance between SNVs Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis filter_density nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False +filter_stats filterstat SNVPhyl filter_stats Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis filter_stats nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False +filter_vcf filtervcf SNVPhyl filter_vcf Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis filter_vcf nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False +find_repeats findrepeat Find repetitive regions on a reference genome using MUMMer Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis find_repeats nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False +snv_matrix snvmatrix Generate matrix of SNV distances Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis snv_matrix nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False +vcf2snvalignment vcf2snvalignment Generates multiple alignment of variant calls Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis vcf2snvalignment nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False +verify_map verify_map Checks the mapping quality of all BAM(s) Up-to-date https://snvphyl.readthedocs.io/en/latest/ Sequence Analysis verify_map nml https://github.com/phac-nml/snvphyl-galaxy 1.8.2 snvphyl-tools 1.8.2 (0/1) (0/1) (0/1) True False +suite_snvphyl SNVPhyl suite defining all dependencies for SNVPhyl To update Sequence Analysis suite_snvphyl_1_2_3 nml https://github.com/phac-nml/snvphyl-galaxy (0/1) (0/1) (0/1) True False +blast2go 1232.0 101.0 blast2go Maps BLAST results to GO annotation terms To update https://github.com/peterjc/galaxy_blast/tree/master/tools/blast2go Ontology Manipulation, Sequence Analysis blast2go peterjc https://github.com/peterjc/galaxy_blast/tree/master/tools/blast2go 0.0.11 b2g4pipe (0/1) (0/1) (0/1) False +blast_rbh 22499.0 121.0 blast_reciprocal_best_hits BLAST Reciprocal Best Hits (RBH) from two FASTA files To update https://github.com/peterjc/galaxy_blast/tree/master/tools/blast_rbh Fasta Manipulation, Sequence Analysis blast_rbh peterjc https://github.com/peterjc/galaxy_blast/tree/master/tools/blast_rbh 0.3.0 biopython 1.70 (0/1) (0/1) (1/1) False +blastxml_to_top_descr 264558.0 159.0 blastxml_to_top_descr Make table of top BLAST match descriptions To update https://github.com/peterjc/galaxy_blast/tree/master/tools/blastxml_to_top_descr Convert Formats, Sequence Analysis, Text Manipulation blastxml_to_top_descr peterjc https://github.com/peterjc/galaxy_blast/tree/master/tools/blastxml_to_top_descr 0.1.2 python (0/1) (0/1) (1/1) False +make_nr make_nr Make a FASTA file non-redundant To update https://github.com/peterjc/galaxy_blast/tree/master/tools/make_nr Fasta Manipulation, Sequence Analysis make_nr peterjc https://github.com/peterjc/galaxy_blast/tree/master/tools/make_nr 0.0.2 biopython 1.70 (0/1) (0/1) (0/1) False +ncbi_blast_plus 365597.0 4066.0 blastxml_to_tabular, get_species_taxids, ncbi_blastdbcmd_info, ncbi_blastdbcmd_wrapper, ncbi_blastn_wrapper, ncbi_blastp_wrapper, ncbi_blastx_wrapper, ncbi_convert2blastmask_wrapper, ncbi_deltablast_wrapper, ncbi_dustmasker_wrapper, ncbi_makeblastdb, ncbi_makeprofiledb, ncbi_psiblast_wrapper, ncbi_rpsblast_wrapper, ncbi_rpstblastn_wrapper, ncbi_segmasker_wrapper, ncbi_tblastn_wrapper, ncbi_tblastx_wrapper NCBI BLAST+ To update https://blast.ncbi.nlm.nih.gov/ Sequence Analysis ncbi_blast_plus devteam https://github.com/peterjc/galaxy_blast/tree/master/tools/ncbi_blast_plus 2.14.1 python (16/18) (16/18) (16/18) False