InterPro:IPR045296|PANTHER:PTN000471017 is not part of respiratory chain but regulates

[hattrill]

InterPro:IPR045296
PANTHER:PTN000471017 ; GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED (PTHR21024)

This corresponds to ETF Regulatory Factor 1 (ETFRF1). Its interaction with the electron transferring flavoprotein (EFT) complex results in the removal of the flavin from the ETFA subunit and stops the transfer of electrons into the respiratory chain. PMID:27499296, PMID:36266680

I think that 'respiratory electron transport chain' is incorrect. 'negative regulation of oxidative phosphorylation' is a more accurate term as ETF is thought of as part of regulating oxidative phosphorylation.

(For PAINT, I have just added this to FBgn0040985, replacing 'negative regulation of cellular respiration'....might be a while coming, but could be used for propagation when it does)

[sarach06]

Hi,
Thank you very much for this. I have updated the term and added the latest reference to the abstract. These changes will be available in the next InterPro release (104.0).
Best regards,
Sara

[ValWood]

'negative regulation of oxidative phosphorylation' is a more accurate term as ETF is thought of as part of oxidative phosphorylation.

should that be NOT part of?

[hattrill]

@ValWood Do you mean that it should be higher up such as 'negative regulation of cellular respiration'?

[ValWood]

it was a pedantic comment but I just edited 'part of' to regulating to make it clearer that these are distinct.
What you have changed to seems correct to me.
v