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Incorrect UniProt KW mapping: UniProt:KW-0418 #5579

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vanaukenk opened this issue Dec 10, 2024 · 2 comments
Open

Incorrect UniProt KW mapping: UniProt:KW-0418 #5579

vanaukenk opened this issue Dec 10, 2024 · 2 comments

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@vanaukenk
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  • UniProt KeyWord (ID and label):UniProt:KW-0418

  • Sequences with problematic annotation (ID + gene/protein name):UniProtKB:O62231, TRY-16

  • Description of issue: TRY-16 has been assigned the keyword mapping for kinase activity, but doesn't appear to have a kinase domain. I ran the protein sequence through InterPro scan and it instead appears to be a member of the Chymotrypsin family Peptidase-S1 (IPR005514).

  • This issue was originally reported by a WormBase user.

Thanks,
--Kimberly

@Antonialock
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Hi Kimberly, @PedroRaposo is investigating this but I think we are waiting to hear from someone who is away.
Unfortunately there are no papers on this protein or I could have manually annotated the protein.

@vanaukenk
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Hi @Antonialock - thank you very much for your reply. I'll look for an update here whenever everyone is back.

I could only find one mention of F35E2.9 after a Textpresso search and unfortunately that paper doesn't shed any additional light on function for F35E2.9.

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