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GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity with no cross reference #29086

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raymond91125 opened this issue Oct 22, 2024 · 0 comments

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raymond91125 commented Oct 22, 2024

GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity lacks EC/RHEA cross references.
The definition reference PMID:16980563 is about Arabidopsis CER4 (FAR3).
Although UniProt annotates it with EC:1.2.1.84 and RHEA:52716 (primary input = a long-chain fatty acyl-CoA), it also states that "The preferred substrates are C24:0 and C26:0. May be unable to use saturated and monounsaturated C16 and C18 acyl-CoA as substrates.". Therefore perhaps this is an activity that requires a new RHEA.

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