diff --git a/.github/workflows/publish_docker_image.yml b/.github/workflows/publish_docker_image.yml
new file mode 100644
index 0000000..447d62a
--- /dev/null
+++ b/.github/workflows/publish_docker_image.yml
@@ -0,0 +1,50 @@
+name: Docker Image CI
+on:
+  push:
+    branches: 
+      - master
+      - demo-*
+    tags: '*'
+
+jobs:
+  build_and_publish:
+    if: github.repository == 'genome-nexus/annotation-tools'
+    runs-on: ubuntu-latest
+    steps:
+      - name: Checkout git repo
+        uses: actions/checkout@v3
+
+      - name: Extract metadata
+        id: meta
+        uses: docker/metadata-action@v4
+        with:
+          images: |
+            genomenexus/annotation-tools
+          # The latest tag will also be generated on tag event with a valid semver tag
+          tags: |
+            type=ref,event=branch
+            type=semver,pattern={{version}}
+
+      # The following two actions are required to build multi-platform images
+      # buildx is an extension of docker build, QUEM is used to convert the binary to varies architecture
+      - name: Set up QEMU
+        uses: docker/setup-qemu-action@v2
+      - name: Set up Docker Buildx
+        uses: docker/setup-buildx-action@v2
+
+      - name: Login to DockerHub
+        uses: docker/login-action@v2
+        with:
+          username: ${{ secrets.DOCKER_USERNAME }}
+          password: ${{ secrets.DOCKER_PASSWORD }}
+
+      - name: Publish Docker Image on Tag
+        uses: docker/build-push-action@v3
+        with:
+          context: .
+          push: true
+          tags: ${{ steps.meta.outputs.tags }}
+          platforms: linux/amd64,linux/arm64
+          file: Dockerfile
+          cache-from: type=gha
+          cache-to: type=gha