diff --git a/bin/cli/run_processing_pipeline.py b/bin/cli/run_processing_pipeline.py
index 4adf60cb..7ab1d2cd 100644
--- a/bin/cli/run_processing_pipeline.py
+++ b/bin/cli/run_processing_pipeline.py
@@ -570,12 +570,12 @@ def stages(self) -> list[pypiper.Stage]:
                 func=compute_locus_pairwise_distances, 
                 f_kwargs=rounds_params,
             ),
-            # pypiper.Stage(
-            #     name="pairwise_distances__regional", 
-            #     func=compute_region_pairwise_distances, 
-            #     f_kwargs=rounds_params,
-            #     nofail=True,
-            # ),
+            pypiper.Stage(
+                name="pairwise_distances__regional", 
+                func=compute_region_pairwise_distances, 
+                f_kwargs=rounds_params,
+                nofail=True,
+            ),
             pypiper.Stage(
                 name="locus_specific_spots_visualisation_data_prep", 
                 func=prep_locus_specific_spots_visualisation, 
diff --git a/docs/pipeline-execution-control-and-rerun.md b/docs/pipeline-execution-control-and-rerun.md
index 454668a7..04e9f3c3 100644
--- a/docs/pipeline-execution-control-and-rerun.md
+++ b/docs/pipeline-execution-control-and-rerun.md
@@ -77,6 +77,7 @@ Below are the sequential pipeline stage names.
 * tracing_QC
 * spot_counts_visualisation__locus_specific
 * pairwise_distances__locus_specific
+* pairwise_distances__regional
 * locus_specific_spots_visualisation_data_prep
 * locus_spot_viewing_prep
 * cross_channel_signal_analysis
\ No newline at end of file