From be8f4ffaa545ac2830721ab21215e51331776023 Mon Sep 17 00:00:00 2001 From: Christina Conrad <114612268+cconrad8@users.noreply.github.com> Date: Wed, 16 Aug 2023 10:26:02 -0400 Subject: [PATCH 1/2] Delete awardees.mdx --- pages/awardees.mdx | 47 ---------------------------------------------- 1 file changed, 47 deletions(-) delete mode 100644 pages/awardees.mdx diff --git a/pages/awardees.mdx b/pages/awardees.mdx deleted file mode 100644 index 4d9d723..0000000 --- a/pages/awardees.mdx +++ /dev/null @@ -1,47 +0,0 @@ -**Devising new strategies to track and prevent breast cancer development in BRCA mutation carriers** -**Joan Brugge** | _Harvard Ludwig Cancer Center and Harvard Medical School_ -* How do basal and luminal breast cells contribute to BRCA-related cancers? -* How do BRCA tumor cells evolve? -* What are the molecular defects during tumor evolution? -* How do we detection cancer evolution in carriers? -* How do we intercept and eradicate tumor development? - ---- - -**Dissecting early pathogenesis of BRCA1/2-associated cancer for risk prediction and prevention** -**Leif Ellisen** | _Harvard Medical School, Massachusetts General Hospital Cancer Center_ -* What are the early changes in cells of BRCA carrier breast tissue? -* What are the BRCA cellular vulnerabilities? -* What are tissue-based markers for prevention approaches? - ---- - -**Interplay and perturbations of the local microbiome and host immune system in breast cancer** -**Charis Eng** | _Cleveland Clinic_ -* What are the differences in microbes found with normal versus BRCA breast cancers? -* How do microbes contribute to immune changes -and cancer? -* Could microbiome engineering prevent cancer? - ---- - -**Determinants of immune activity and molecular features in BRCA1/2 mutation carriers** -**Katherine Nathanson** | _University of Pennsylvania_ -* What are the immune functional status in BRCA carriers? -* Are there associations between molecular and immune status with therapeutic response and survival? - ---- - -**Dissection of BRCA-mediated Tumor Suppression Pathways** -**Patrick Sung** | _Univ. of Texas Health Science Center at San Antonio_ -* What are the regulators of BRCA function? -* What are BRCA-independent DNA repair pathways? -* What are the DNA repair mechanisms? -* What are the drug vulnerabilities of BRCA deficient cells? - ---- - -**Early detection of cancer in high-risk BRCA mutation carriers using liquid biopsies** -**Victor Velculescu** | _Johns Hopkins University_ -* What are the molecular characteristics of circulation free DNA in BRCA carriers with and without cancer? -* What is the strategy for screening? From ba096b94275115d4d78f4f38aca5956e70648cd0 Mon Sep 17 00:00:00 2001 From: Christina Conrad <114612268+cconrad8@users.noreply.github.com> Date: Wed, 16 Aug 2023 10:26:15 -0400 Subject: [PATCH 2/2] Update _meta.json --- pages/_meta.json | 3 +-- 1 file changed, 1 insertion(+), 2 deletions(-) diff --git a/pages/_meta.json b/pages/_meta.json index 22c8ed5..3313374 100644 --- a/pages/_meta.json +++ b/pages/_meta.json @@ -1,9 +1,8 @@ { "index": "Home", "governance": "Governance", - "awardees": "Awardees", "onboarding": "Onboarding", "data-model": "Data Model", "data-portal": "Data Portal", "faq": "Frequently Asked Questions" -} \ No newline at end of file +}