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It's been a long time and I'm not working with the tool anymore but as far as I remember I solved the issue by filtering out the shorter reads ( like shorter than 50 bp or so depending on your data ). I'm not sure why they are related or why this problem happens.
For some samples I have this error. I don't know the reason and how to fix it. Here is the error message:
terminate called after throwing an instance of 'std::out_of_range'
what(): basic_string::substr: __pos (which is 145) > this->size() (which is 105)
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