diff --git a/manual/deploy/start_seafile_at_system_bootup.md b/manual/deploy/start_seafile_at_system_bootup.md
index 5801c5f9b..a03c52699 100644
--- a/manual/deploy/start_seafile_at_system_bootup.md
+++ b/manual/deploy/start_seafile_at_system_bootup.md
@@ -1,8 +1,116 @@
 # Start Seafile at System Bootup
 
-## Seafile component
+## For systems running systemd and python virtual environments
 
-Create systemd service file /etc/systemd/system/seafile.service
+* For example Debian 12
+Create systemd service files, change **${seafile_dir}** to your
+**seafile** installation location and **seafile** to user, who runs
+**seafile** (if appropriate). Then you need to reload systemd's daemons:
+**systemctl daemon-reload**.
+
+Firstly, you should create a script to activate the python virtual environment, which goes in the **${seafile_dir}** directory.  Put another way, it does not go in "seafile-server-latest", but the directory above that.  Throughout this manual the examples use /opt/seafile for this directory, but you might have chosen to use a different directory.
+
+```
+sudo vim /opt/seafile/run_with_venv.sh
+```
+
+The content of the file is:
+
+```
+#!/bin/bash
+# Activate the python virtual environment (venv) before starting one of the seafile scripts
+
+dir_name="$(dirname $0)"
+source "${dir_name}/python-venv/bin/activate"
+script="$1"
+shift 1
+
+echo "${dir_name}/seafile-server-latest/${script}" "$@"
+"${dir_name}/seafile-server-latest/${script}" "$@"
+```
+make this script executable
+```
+sudo chmod 755 /opt/seafile/run_with_venv.sh
+```
+
+### Seafile component
+
+```
+sudo vim /etc/systemd/system/seafile.service
+
+```
+
+The content of the file is:
+
+```
+[Unit]
+Description=Seafile
+# add mysql.service or postgresql.service depending on your database to the line below
+After=network.target
+
+[Service]
+Type=forking
+ExecStart=bash ${seafile_dir}/run_with_venv.sh seafile.sh start
+ExecStop=bash ${seafile_dir}/seafile-server-latest/seafile.sh stop
+LimitNOFILE=infinity
+User=seafile
+Group=seafile
+
+[Install]
+WantedBy=multi-user.target
+
+```
+
+### Seahub component
+
+```
+sudo vim /etc/systemd/system/seahub.service
+
+```
+
+The content of the file is (please dont forget to change it if you want to run fastcgi):
+
+```
+[Unit]
+Description=Seafile hub
+After=network.target seafile.service
+
+[Service]
+Type=forking
+# change start to start-fastcgi if you want to run fastcgi
+ExecStart=bash ${seafile_dir}/run_with_venv.sh seahub.sh start
+ExecStop=bash ${seafile_dir}/seafile-server-latest/seahub.sh stop
+User=seafile
+Group=seafile
+
+[Install]
+WantedBy=multi-user.target
+
+```
+
+### Seafile cli client (optional)
+
+The client doesn't require any packages from pip, so this is the same as for systems without pythong virtual environments.  See that section below.
+
+### Enable service start on system boot
+
+```
+sudo systemctl enable seafile.service
+sudo systemctl enable seahub.service
+sudo systemctl enable seafile-client.service   # optional
+```
+
+## For systems running systemd without python virtual environment
+
+* For example Debian 8 through Debian 11, Linux Ubuntu 15.04 and newer
+
+Create systemd service files, change **${seafile_dir}** to your
+**seafile** installation location and **seafile** to user, who runs
+**seafile** (if appropriate). Then you need to reload systemd's daemons:
+**systemctl daemon-reload**.
+
+
+### Seafile component
 
 ```
 sudo vim /etc/systemd/system/seafile.service
@@ -31,7 +139,7 @@ WantedBy=multi-user.target
 ```
 
 
-## Seahub component
+### Seahub component
 
 Create systemd service file /etc/systemd/system/seahub.service
 
@@ -61,7 +169,7 @@ WantedBy=multi-user.target
 ```
 
 
-## Seafile cli client (optional)
+### Seafile cli client (optional)
 
 Create systemd service file /etc/systemd/system/seafile-client.service 
 
@@ -96,7 +204,7 @@ WantedBy=multi-user.target
 
 ```
 
-## Enable service start on system boot
+### Enable service start on system boot
 
 ```
 sudo systemctl enable seafile.service
diff --git a/manual/deploy/using_mysql.md b/manual/deploy/using_mysql.md
index c83fb7414..8f6c9869b 100644
--- a/manual/deploy/using_mysql.md
+++ b/manual/deploy/using_mysql.md
@@ -97,7 +97,7 @@ sudo pip3 install --timeout=3600 django==3.2.* future==0.18.* mysqlclient==2.1.*
 
 ```
 
-**For Seafile 11.0.x**
+**For Seafile 11.0.x (Debian 11, Ubuntu 22.04, etc.)**
 
 ```
 # Ubuntu 22.04 (almost the same for Ubuntu 20.04 and Debian 11, Debian 10)
@@ -123,12 +123,35 @@ sudo pip3 install --timeout=3600 django==4.2.* future==0.18.* mysqlclient==2.1.*
 
 ```
 
+**For Seafile 11.0.x on Debian 12**
+
+Debian 12 (and most newer distributions) are now discouraging system-wide installation of python modules with pip.  It is preferred now to install modules into a virtual environment which keeps them separate from the files installed by the system package manager, and enables diffeerent versions to be installed for different applications.  With these python virtual environments (venv for short) to work, you have to activate the venv to make the packages installed in it available to the programs you run.  That is done here with "source python-venv/bin/activate".  Also be aware of the changes in [Start Seafile at System Bootup](./start_seafile_at_system_bootup.md) in this manual.
+
+```
+# Debian 12 (almost the same as Debian 11, but with python virtual environments to keep pip installs from conflicting with apt-get installs)
+sudo apt-get update
+sudo apt-get install -y python3 python3-dev python3-setuptools python3-pip libmariadb-dev-compat ldap-utils libldap2-dev python3.11-venv
+sudo apt-get install -y memcached libmemcached-dev
+
+cd /opt/seafile
+
+# create the vitual environment in the python-venv directory
+python3 -m venv python-venv
+
+# activate the venv
+source python-venv/bin/activate
+# Notice that this will usually change your prompt so you know the venv is active
+
+# install packages into the active venv with pip (sudo isn't needed because this is installing in the venv, not system-wide).
+pip3 install --timeout=3600  django==4.2.* future==0.18.* mysqlclient==2.1.* pymysql pillow==10.0.* pylibmc captcha==0.4 markupsafe==2.0.1 jinja2 sqlalchemy==2.0.18 psd-tools django-pylibmc django_simple_captcha==0.5.* djangosaml2==1.5.* pysaml2==7.2.* pycryptodome==3.16.* cffi==1.15.1 lxml python-ldap==3.4.3
+```
+
 ### Creating the program directory
 
 The standard directory for Seafile's program files is `/opt/seafile`. Create this directory and change into it:
 
 ```
-mkdir /opt/seafile
+sudo mkdir /opt/seafile
 cd /opt/seafile
 ```
 
@@ -141,13 +164,13 @@ It is good practice not to run applications as root.
 Create a new user and follow the instructions on the screen:
 
 ```
-adduser seafile
+sudo adduser seafile
 ```
 
 Change ownership of the created directory to the new user:
 
 ```
-chown -R seafile: /opt/seafile
+sudo chown -R seafile: /opt/seafile
 ```
 
 All the following steps are done as user seafile.
@@ -212,6 +235,9 @@ Note: While ccnet server was merged into the seafile-server in Seafile 8.0, the
 Run the script as user seafile:
 
 ```
+# For installations using python virtual environment, activate it if it isn't already active
+source python-venv/bin/activate
+
 cd seafile-server-8.0.4
 ./setup-seafile-mysql.sh
 
@@ -362,9 +388,12 @@ To access Seafile's web interface and to create working sharing links without a
 
 ## Starting Seafile Server
 
-Run the following commands in `/opt/seafile-server-latest`:
+Run the following commands in `/opt/seafile/seafile-server-latest`:
 
 ```
+# For installations using python virtual environment, activate it if it isn't already active
+source python-venv/bin/activate
+
 ./seafile.sh start # starts seaf-server
 ./seahub.sh start  # starts seahub
 
@@ -410,6 +439,9 @@ pkill -f "seahub"
 ### Restarting
 
 ```
+# For installations using python virtual environment, activate it if it isn't already active
+source python-venv/bin/activate
+
 ./seafile.sh restart
 ./seahub.sh restart
 
diff --git a/manual/deploy_pro/download_and_setup_seafile_professional_server.md b/manual/deploy_pro/download_and_setup_seafile_professional_server.md
index b100bf52b..6aa14cd68 100644
--- a/manual/deploy_pro/download_and_setup_seafile_professional_server.md
+++ b/manual/deploy_pro/download_and_setup_seafile_professional_server.md
@@ -87,7 +87,7 @@ sudo pip3 install --timeout=3600 django==3.2.* future==0.18.* mysqlclient==2.1.*
     psd-tools django-pylibmc django_simple_captcha==0.5.20 pycryptodome==3.16.* cffi==1.15.1 lxml
 ```
 
-**For Seafile 11.0.x**
+**For Seafile 11.0.x (Debian 11, Ubuntu 20.04, Centos 8, etc.)**
 
 ```
 # on Ubuntu 22.04 (on Ubuntu 20.04/Debian 11/Debian 10, it is almost the same)
@@ -125,6 +125,32 @@ sudo pip3 install --timeout=3600 django==4.2.* future==0.18.* mysqlclient==2.1.*
 
 **Note**: The recommended deployment option for Seafile PE on CentOS/Redhat is [Docker](https://manual.seafile.com/docker/pro-edition/deploy_seafile_pro_with_docker/).
 
+**For Seafile 11.0.x on Debian 12**
+
+Debian 12 (and most newer distributions) are now discouraging system-wide installation of python modules with pip.  It is preferred now to install modules into a virtual environment which keeps them separate from the files installed by the system package manager, and enables diffeerent versions to be installed for different applications.  With these python virtual environments (venv for short) to work, you have to activate the venv to make the packages installed in it available to the programs you run.  That is done here with "source python-venv/bin/activate".  Also be aware of the changes in [Start Seafile at System Bootup](../deploy/start_seafile_at_system_bootup.md) in this manual.
+
+```
+# Debian 12 (almost the same as Debian 11, but with python virtual environments to keep pip installs from conflicting with apt-get installs)
+sudo apt-get update
+sudo apt-get install -y python3 python3-dev python3-setuptools python3-pip python3-ldap libmysqlclient-dev ldap-utils libldap2-dev dnsutils
+sudo apt-get install -y memcached libmemcached-dev
+sudo apt-get install -y poppler-utils
+
+cd /opt/seafile
+
+# create the vitual environment in the python-venv directory
+python3 -m venv python-venv
+
+# activate the venv
+source python-venv/bin/activate
+# Notice that this will usually change your prompt so you know the venv is active
+
+# install packages into the active venv with pip (sudo isn't needed because this is installing in the venv, not system-wide).
+pip3 install --timeout=3600 django==4.2.* future==0.18.* mysqlclient==2.1.* \
+    pymysql pillow==10.0.* pylibmc captcha==0.4 markupsafe==2.0.1 jinja2 sqlalchemy==2.0.18 \
+    psd-tools django-pylibmc django_simple_captcha==0.5.* djangosaml2==1.5.* pysaml2==7.2.* pycryptodome==3.16.* cffi==1.15.1 python-ldap==3.4.3 lxml
+```
+
 ### Installing Java Runtime Environment
 
 
@@ -385,9 +411,12 @@ You need at least setup HTTP to make Seafile's web interface work. This manual p
 
 ## Starting Seafile Server
 
-Run the following commands in `/opt/seafile-server-latest`:
+Run the following commands in `/opt/seafile/seafile-server-latest`:
 
 ```
+# For installations using python virtual environment, activate it if it isn't already active
+source python-venv/bin/activate
+
 ./seafile.sh start # Start Seafile service
 ./seahub.sh start  # Start seahub website, port defaults to 127.0.0.1:8000
 ```