diff --git a/aism-base.json b/aism-base.json index fea9778..6cbfc63 100644 --- a/aism-base.json +++ b/aism-base.json @@ -40,9 +40,9 @@ "val" : "https://creativecommons.org/licenses/by/4.0/" }, { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-03-16" + "val" : "2024-05-11" } ], - "version" : "http://purl.obolibrary.org/obo/aism/releases/2024-03-16/aism-base.json" + "version" : "http://purl.obolibrary.org/obo/aism/releases/2024-05-11/aism-base.json" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/AISM_0000000", @@ -2795,11 +2795,11 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The anatomical space adjacent to two cuticular punctures." + "val" : "The distance between two cuticular punctures." }, "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000232", - "val" : "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" + "val" : "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" } ] } }, { diff --git a/aism-base.obo b/aism-base.obo index 43ba039..c662822 100644 --- a/aism-base.obo +++ b/aism-base.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: aism/releases/2024-03-16/aism-base.owl +data-version: aism/releases/2024-05-11/aism-base.owl ontology: aism/aism-base property_value: http://purl.org/dc/elements/1.1/contributor "Giulio Montanaro (gmontanaro) https://orcid.org/0000-0003-0836-1364" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "István Mikó (imiko) https://orcid.org/0000-0003-2938-9075" xsd:string @@ -13,7 +13,7 @@ property_value: http://purl.org/dc/terms/license https://creativecommons.org/lic property_value: IAO:0000700 "http://purl.obolibrary.org/obo/AISM_0000174" xsd:string property_value: IAO:0000700 "http://purl.obolibrary.org/obo/PATO_0000001" xsd:string property_value: IAO:0000700 "http://purl.obolibrary.org/obo/UBERON_0001062" xsd:string -property_value: owl:versionInfo "2024-03-16" xsd:string +property_value: owl:versionInfo "2024-05-11" xsd:string [Term] id: AISM:0000000 @@ -2266,8 +2266,8 @@ relationship: parallel_to AISM:0000377 {http://purl.org/dc/elements/1.1/contribu [Term] id: AISM:0000376 name: interpunctural distance {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} -def: "The anatomical space adjacent to two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} -property_value: IAO:0000232 "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} +def: "The distance between two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} +property_value: IAO:0000232 "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} [Term] id: AISM:0000377 diff --git a/aism-base.owl b/aism-base.owl index 8662092..5c36acb 100644 --- a/aism-base.owl +++ b/aism-base.owl @@ -38,7 +38,7 @@ xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#" xmlns:caloha-reqs-vetted="http://purl.obolibrary.org/obo/caloha-reqs-vetted#"> - + http://purl.obolibrary.org/obo/AISM_0000174 http://purl.obolibrary.org/obo/PATO_0000001 http://purl.obolibrary.org/obo/UBERON_0001062 @@ -51,7 +51,7 @@ Ontology for the Anatomy of the Insect SkeletoMuscular system - 2024-03-16 + 2024-05-11 @@ -17943,15 +17943,20 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 - The anatomical space adjacent to two cuticular punctures. - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + The distance between two cuticular punctures. + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 interpunctural distance - + - + @@ -17966,14 +17971,19 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 - The anatomical space adjacent to two cuticular punctures. + The distance between two cuticular punctures. gmontanaro https://orcid.org/0000-0003-0836-1364 2023-06-04 - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 jgiron https://orcid.org/0000-0002-0851-6883 2024-02-14 @@ -45927,6 +45937,12 @@ starasov https://orcid.org/0000-0001-5237-2330 + + + + + + @@ -46137,12 +46153,6 @@ starasov https://orcid.org/0000-0001-5237-2330 - - - - - - diff --git a/aism-full.json b/aism-full.json index 3d25b29..02f9145 100644 --- a/aism-full.json +++ b/aism-full.json @@ -37,9 +37,9 @@ "val" : "https://creativecommons.org/licenses/by/4.0/" }, { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-03-16" + "val" : "2024-05-11" } ], - "version" : "http://purl.obolibrary.org/obo/aism/releases/2024-03-16/aism-full.json" + "version" : "http://purl.obolibrary.org/obo/aism/releases/2024-05-11/aism-full.json" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/IAO_0000002", @@ -3161,11 +3161,11 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The anatomical space adjacent to two cuticular punctures." + "val" : "The distance between two cuticular punctures." }, "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000232", - "val" : "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" + "val" : "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" } ] } }, { @@ -158479,9 +158479,6 @@ }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "has_characteristic" - }, { - "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://github.com/oborel/obo-relations/pull/284" } ] } }, { @@ -164349,6 +164346,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000232", "val" : "See github ticket https://github.com/oborel/obo-relations/issues/497" + }, { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0001-9625-1899" + }, { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0003-2620-0345" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2021-11-08T12:00:00Z" @@ -305123,10 +305126,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008150", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000015" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0008150", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -315350,7 +315349,7 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0042391", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/BFO_0000015" + "obj" : "http://purl.obolibrary.org/obo/BFO_0000003" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0042391", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", @@ -332731,6 +332730,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0099738", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/GO_0005938" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0100001", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/BFO_0000015" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0100001", "pred" : "is_a", @@ -426416,10 +426419,6 @@ "sub" : "http://purl.obolibrary.org/obo/BFO_0000004", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000004" - }, { - "sub" : "http://purl.obolibrary.org/obo/BFO_0000015", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", - "obj" : "http://purl.obolibrary.org/obo/BFO_0000015" }, { "sub" : "http://purl.obolibrary.org/obo/BFO_0000017", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", @@ -426437,13 +426436,6 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000031" } ] - }, { - "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "allValuesFromEdges" : [ { - "sub" : "http://purl.obolibrary.org/obo/BFO_0000020", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" - } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", "allValuesFromEdges" : [ { @@ -426883,7 +426875,7 @@ "rangeClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ] }, { "predicateId" : "http://purl.obolibrary.org/obo/RO_0000057", - "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003", "http://purl.obolibrary.org/obo/BFO_0000015" ], + "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], "rangeClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000002" ] }, { "predicateId" : "http://purl.obolibrary.org/obo/RO_0000079", diff --git a/aism-full.obo b/aism-full.obo index 53cc1b9..0a698fe 100644 --- a/aism-full.obo +++ b/aism-full.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: aism/releases/2024-03-16/aism-full.owl +data-version: aism/releases/2024-05-11/aism-full.owl subsetdef: 1_STAR "" subsetdef: 2_STAR "" subsetdef: 3_STAR "" @@ -100,7 +100,7 @@ property_value: http://purl.org/dc/elements/1.1/contributor "István Mikó (imik property_value: http://purl.org/dc/elements/1.1/contributor "Jennifer C. Girón (jgiron) https://orcid.org/0000-0002-0851-6883" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "Luis A. González Montaña (lagonzalezmo) https://orcid.org/0000-0002-9136-9932" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "Sergei Tarasov (starasov) https://orcid.org/0000-0001-5237-2330" xsd:string -property_value: owl:versionInfo "2024-03-16" xsd:string +property_value: owl:versionInfo "2024-05-11" xsd:string [Term] id: AISM:0000000 @@ -2353,8 +2353,8 @@ relationship: parallel_to AISM:0000377 {http://purl.org/dc/elements/1.1/contribu [Term] id: AISM:0000376 name: interpunctural distance {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} -def: "The anatomical space adjacent to two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} -property_value: curator_notes "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} +def: "The distance between two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} +property_value: curator_notes "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} [Term] id: AISM:0000377 @@ -6014,7 +6014,6 @@ def: "An occurrent that has temporal proper parts and for some time t, p s-depen def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. is_a: BFO:0000003 ! occurrent -relationship: part_of BFO:0000015 {all_only="true"} ! process property_value: BFO:0000179 "process" xsd:string property_value: BFO:0000180 "Process" xsd:string property_value: editor_note "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string @@ -6096,7 +6095,6 @@ def: "b is a specifically dependent continuant = Def. b is a continuant & there comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000031 ! generically dependent continuant -relationship: has_part BFO:0000020 {all_only="true"} ! characteristic relationship: part_of BFO:0000020 {all_only="true"} ! characteristic property_value: BFO:0000179 "sdc" xsd:string property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string @@ -29154,7 +29152,6 @@ synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process is_a: BFO:0000015 ! process -relationship: has_part GO:0003674 ! molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI created_by: jl creation_date: 2012-09-19T15:05:24Z @@ -41513,7 +41510,7 @@ id: GO:0042391 name: regulation of membrane potential namespace: biological_process def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732] -is_a: BFO:0000015 ! process +is_a: BFO:0000003 ! occurrent relationship: has_part GO:0034220 ! monoatomic ion transmembrane transport [Term] @@ -62501,6 +62498,7 @@ id: GO:0100001 name: regulation of skeletal muscle contraction by action potential namespace: biological_process def: "Any action potential process that regulates skeletal muscle contraction." [GOC:cjm, GOC:obol] +is_a: BFO:0000015 ! process is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: regulates GO:0003009 ! skeletal muscle contraction @@ -136246,6 +136244,8 @@ synonym: "utilizes" BROAD [] xref: RO:0017001 property_value: curator_notes "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input." xsd:string property_value: curator_notes "See github ticket https://github.com/oborel/obo-relations/issues/497" xsd:string +property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9625-1899 +property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2620-0345 property_value: IAO:0000112 "A diagnostic testing device utilizes a specimen." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0001-9625-1899 property_value: IAO:0000117 https://orcid.org/0000-0003-2620-0345 @@ -136764,7 +136764,6 @@ property_value: IAO:0000112 "this vase is bearer of this fragility" xsd:string property_value: IAO:0000118 "bearer_of" xsd:string property_value: IAO:0000118 "is bearer of" xsd:string property_value: RO:0001900 RO:0001901 -property_value: seeAlso "https://github.com/oborel/obo-relations/pull/284" xsd:string range: BFO:0000020 ! characteristic is_inverse_functional: true @@ -137081,7 +137080,6 @@ property_value: IAO:0000112 "this investigation has participant this investigato property_value: IAO:0000112 "this process has participant this input material (or this output material)" xsd:string property_value: IAO:0000118 "has_participant" xsd:string domain: BFO:0000003 ! occurrent -domain: BFO:0000015 ! process range: BFO:0000002 ! continuant holds_over_chain: has_part has_participant diff --git a/aism-full.owl b/aism-full.owl index b6bd4ed..0a2d557 100644 --- a/aism-full.owl +++ b/aism-full.owl @@ -42,7 +42,7 @@ xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#" xmlns:caloha-reqs-vetted="http://purl.obolibrary.org/obo/caloha-reqs-vetted#"> - + http://purl.obolibrary.org/obo/AISM_0000174 http://purl.obolibrary.org/obo/PATO_0000001 http://purl.obolibrary.org/obo/UBERON_0001062 @@ -54,7 +54,7 @@ The ontology for the Anatomy of the Insect SkeletoMuscular system (AISM) contains terms used to describe the cuticle - as a single anatomical structure - and the skeletal muscle system, to be used in insect biodiversity research. Ontology for the Anatomy of the Insect SkeletoMuscular system - 2024-03-16 + 2024-05-11 @@ -3148,9 +3148,7 @@ every c that is a concretization of g specifically denotes r RO:0000053 has_characteristic - has characteristic has characteristic - https://github.com/oborel/obo-relations/pull/284 @@ -3181,7 +3179,6 @@ every c that is a concretization of g specifically denotes r - @@ -3198,7 +3195,6 @@ every c that is a concretization of g specifically denotes r http://www.obofoundry.org/ro/#OBO_REL:has_participant RO:0000057 has_participant - has participant has participant @@ -5628,7 +5624,6 @@ Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.RO:0002333 enabled_by - enabled by enabled by https://wiki.geneontology.org/Enabled_by @@ -7853,6 +7848,8 @@ For example, A and B may be gene products and binding of B by A positively regul A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input. See github ticket https://github.com/oborel/obo-relations/issues/497 + + 2021-11-08T12:00:00Z 2021-11-08T12:00:00Z utilizes @@ -25810,15 +25807,20 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 - The anatomical space adjacent to two cuticular punctures. - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + The distance between two cuticular punctures. + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 interpunctural distance - + - + @@ -25833,14 +25835,19 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 - The anatomical space adjacent to two cuticular punctures. + The distance between two cuticular punctures. gmontanaro https://orcid.org/0000-0003-0836-1364 2023-06-04 - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 jgiron https://orcid.org/0000-0002-0851-6883 2024-02-14 @@ -53910,12 +53917,6 @@ starasov https://orcid.org/0000-0001-5237-2330 - - - - - - process Process a process of cell-division, \ a beating of the heart @@ -54113,12 +54114,6 @@ starasov https://orcid.org/0000-0001-5237-2330 - - - - - - sdc SpecificallyDependentContinuant @@ -98895,21 +98890,21 @@ The modern definition of neurosecretion has evolved to include the release of an - + An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion. https://orcid.org/0000-0002-1425-877X 2023-10-13T11:22:42Z UB cell ureteric bud cell - + - + PMID:9374839 @@ -114880,7 +114875,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -114905,14 +114900,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0005319 lipid transporter activity - + - + GO_REF:0000090 @@ -114993,7 +114988,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -115014,14 +115009,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0005326 neurotransmitter transmembrane transporter activity - + - + GO_REF:0000090 @@ -115250,32 +115245,32 @@ The modern definition of neurosecretion has evolved to include the release of an + - A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -124820,12 +124815,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. A process that emerges from two or more causally-connected macromolecular activities and has evolved to achieve a biological objective. @@ -125336,7 +125325,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + Enables the transfer of a protein from one side of a membrane to the other. GO:0015266 GO:0015463 @@ -125365,14 +125354,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0008320 protein transmembrane transporter activity - + - + GO_REF:0000090 @@ -136630,7 +136619,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -136645,14 +136634,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015075 monoatomic ion transmembrane transporter activity - + - + GO_REF:0000090 @@ -136943,7 +136932,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -136966,14 +136955,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015114 phosphate ion transmembrane transporter activity - + - + GO_REF:0000090 @@ -137007,7 +136996,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137031,14 +137020,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015116 sulfate transmembrane transporter activity - + - + GO_REF:0000090 @@ -137083,7 +137072,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137095,14 +137084,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015123 acetate transmembrane transporter activity - + - + GO_REF:0000090 @@ -137277,7 +137266,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137292,14 +137281,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015144 carbohydrate transmembrane transporter activity - + - + GO_REF:0000090 @@ -137371,7 +137360,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137385,14 +137374,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015149 hexose transmembrane transporter activity - + - + GO_REF:0000090 @@ -137477,7 +137466,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137541,14 +137530,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015171 amino acid transmembrane transporter activity - + - + GO_REF:0000090 @@ -164542,7 +164531,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -229702,6 +229691,7 @@ The modern definition of neurosecretion has evolved to include the release of an + @@ -243635,7 +243625,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -243650,14 +243640,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:1901505 carbohydrate derivative transmembrane transporter activity - + - + GO_REF:0000090 @@ -313393,9 +313383,9 @@ When there is no such string, it is almost always because the entities take the - - - + + + @@ -313439,34 +313429,34 @@ When there is no such string, it is almost always because the entities take the islet of Langerhans http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png - + - + - + - + PMID:16417468 - + PMID:16417468 - + PMID:16417468 @@ -313774,7 +313764,7 @@ When there is no such string, it is almost always because the entities take the - + @@ -313820,7 +313810,7 @@ When there is no such string, it is almost always because the entities take the sympathetic nervous system http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png - + @@ -313833,7 +313823,7 @@ When there is no such string, it is almost always because the entities take the - + FMA MA ZFA-modified-from-isa @@ -314039,7 +314029,7 @@ When there is no such string, it is almost always because the entities take the - + @@ -314052,9 +314042,9 @@ When there is no such string, it is almost always because the entities take the - - - + + + @@ -314102,19 +314092,19 @@ When there is no such string, it is almost always because the entities take the endocrine pancreas - + - + - + - + @@ -314127,7 +314117,7 @@ When there is no such string, it is almost always because the entities take the - + AAO FMA XAO @@ -314135,19 +314125,19 @@ When there is no such string, it is almost always because the entities take the - + GO - + GO - + GO @@ -314358,7 +314348,7 @@ When there is no such string, it is almost always because the entities take the - + @@ -314386,14 +314376,14 @@ When there is no such string, it is almost always because the entities take the compound eye https://github.com/obophenotype/uberon/issues/457 - + - + PMID:21062451 @@ -314475,7 +314465,7 @@ When there is no such string, it is almost always because the entities take the - + @@ -314516,14 +314506,14 @@ When there is no such string, it is almost always because the entities take the camera-type eye - + - + definitional @@ -314961,7 +314951,7 @@ When there is no such string, it is almost always because the entities take the - + A lamina propria that is part of a respiratory airway. EMAPA:35877 FMA:265157 @@ -314984,14 +314974,14 @@ When there is no such string, it is almost always because the entities take the UBERON:0000031 lamina propria of trachea - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -315302,8 +315292,8 @@ When there is no such string, it is almost always because the entities take the - - + + @@ -315354,11 +315344,11 @@ When there is no such string, it is almost always because the entities take the tendon http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg - + - + @@ -315371,13 +315361,13 @@ When there is no such string, it is almost always because the entities take the - + OG - + AEO @@ -315452,8 +315442,8 @@ When there is no such string, it is almost always because the entities take the - - + + A biological tissue mass, most commonly a mass of nerve cell bodies. TODO - check vert vs invert. Other species: Any of a number of aggregations of neurons, glial cells and their processes, surrounded by a glial cell and connective tissue sheath (plural: ganglia). // Subdivision of neural tree (organ) which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord); together with a nucleus and its associated nerve, it constitutes a neural tree (organ). Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. // a cluster of nerve cells and associated glial cells (nuclear location) // Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system. @@ -315505,11 +315495,11 @@ When there is no such string, it is almost always because the entities take the ganglion - + - + @@ -315522,13 +315512,13 @@ When there is no such string, it is almost always because the entities take the - + EHDAA2 - + Bgee:AN @@ -315720,7 +315710,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -315780,14 +315770,14 @@ https://doi.org/10.1515/9783110264043 ureter https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + GO @@ -315859,8 +315849,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -315910,25 +315900,25 @@ https://doi.org/10.1515/9783110264043 urethra https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png - + - + - + pelvic part of UG sinus gives rise to prostatic and membranous parts of urethra Wikipedia - + Wikipedia @@ -316471,7 +316461,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -316492,14 +316482,14 @@ https://doi.org/10.1515/9783110264043 respiratory tract - + - + NCBIBook:NBK10107 @@ -317162,7 +317152,7 @@ https://doi.org/10.1515/9783110264043 - + The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube) @@ -317188,7 +317178,7 @@ https://doi.org/10.1515/9783110264043 external ectoderm http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png - + @@ -317201,7 +317191,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -317625,15 +317615,15 @@ https://doi.org/10.1515/9783110264043 - - + + - + @@ -317669,34 +317659,34 @@ https://doi.org/10.1515/9783110264043 metanephros - + - + - + - + definitional - + GO - + ISBN:9780878932504 @@ -317852,8 +317842,8 @@ https://doi.org/10.1515/9783110264043 - - + + An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]. Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG] Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts[VHOG:0000541]. @@ -317880,11 +317870,11 @@ https://doi.org/10.1515/9783110264043 ureteric bud - + - + @@ -317897,13 +317887,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + ISBN:9780878932504 @@ -317989,7 +317979,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -318032,14 +318022,14 @@ https://doi.org/10.1515/9783110264043 morula http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png - + - + EHDAA2 @@ -318196,8 +318186,8 @@ https://doi.org/10.1515/9783110264043 - - + + A mass of cells that develop into the body of the embryo and some extraembryonic tissues. A group of cells found in the mammalian blastocyst that give rise to the embryo. [Biology_Online][VHOG] A small sphere of cells known as the inner cell mass lies within the trophoblast (of all eutherian mammals).[well established][VHOG] @@ -318225,24 +318215,24 @@ https://doi.org/10.1515/9783110264043 inner cell mass https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg - + - + - + Wikipedia - + Wikipedia @@ -318309,7 +318299,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -318342,14 +318332,14 @@ https://doi.org/10.1515/9783110264043 trophoblast https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg - + - + MP-def PMID:19829370 @@ -318415,7 +318405,7 @@ https://doi.org/10.1515/9783110264043 - + A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc. embryonic disc embryonic shield @@ -318435,14 +318425,14 @@ https://doi.org/10.1515/9783110264043 bilaminar disc http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png - + - + Wikipedia @@ -318543,7 +318533,7 @@ https://doi.org/10.1515/9783110264043 - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -318554,14 +318544,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0000094 membrane organ - + - + FMA-def @@ -318584,7 +318574,7 @@ https://doi.org/10.1515/9783110264043 - + Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]. A subpopulation of the cephalic neural crest that emerges from the otic level to the anterior limit of somite 4. It migrates to the heart and is essential for the septation of the outflow track[DOI:10.1242/dev.091751]. ZFA treats this as a subtype of NC. @@ -318601,14 +318591,14 @@ https://doi.org/10.1515/9783110264043 cardiac neural crest - + - + Wikipedia @@ -319075,7 +319065,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -319111,14 +319101,14 @@ https://doi.org/10.1515/9783110264043 gastrula stage - + - + BILS @@ -319637,7 +319627,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -319665,7 +319655,7 @@ https://doi.org/10.1515/9783110264043 lung bud http://upload.wikimedia.org/wikipedia/commons/7/71/Gray948.png - + @@ -319678,7 +319668,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -319790,7 +319780,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -319816,14 +319806,14 @@ https://doi.org/10.1515/9783110264043 neural nucleus - + - + we limit this structure by definition to chordate and vertebrate nervous systems @@ -320040,7 +320030,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -320079,14 +320069,14 @@ https://doi.org/10.1515/9783110264043 anal canal https://upload.wikimedia.org/wikipedia/commons/0/01/Gray1078.png - + - + Wikipathways:WP2062 @@ -320269,8 +320259,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -320303,24 +320293,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0000162 cloaca - + - + - + ZFA - + AAO @@ -320402,8 +320392,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -320422,24 +320412,24 @@ https://doi.org/10.1515/9783110264043 embryonic cloaca - + - + - + EHDAA2 - + EHDAA2 @@ -320462,7 +320452,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -320504,14 +320494,14 @@ https://doi.org/10.1515/9783110264043 primitive urogenital sinus http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + - + MP-def @@ -321067,7 +321057,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -321113,14 +321103,14 @@ https://doi.org/10.1515/9783110264043 pair of lungs - + - + FMA-abduced @@ -321295,21 +321285,21 @@ https://doi.org/10.1515/9783110264043 - + - + - + A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. @@ -321353,34 +321343,34 @@ https://doi.org/10.1515/9783110264043 blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -321496,7 +321486,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -321531,7 +321521,7 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/9/97/Gray136.png https://upload.wikimedia.org/wikipedia/commons/5/5b/Frontal_bone.png - + @@ -321544,7 +321534,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -321747,7 +321737,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -321780,14 +321770,14 @@ https://doi.org/10.1515/9783110264043 atlanto-occipital joint http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png - + - + FMA-abduced-lr @@ -322243,7 +322233,7 @@ https://doi.org/10.1515/9783110264043 - + The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin. BTO:0000503 EMAPA:27181 @@ -322254,7 +322244,7 @@ https://doi.org/10.1515/9783110264043 gastric gland - + @@ -322267,7 +322257,7 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0073040584 @@ -323219,7 +323209,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -323246,7 +323236,7 @@ https://doi.org/10.1515/9783110264043 syncytiotrophoblast http://upload.wikimedia.org/wikipedia/commons/d/df/Gray36.png - + @@ -323259,7 +323249,7 @@ https://doi.org/10.1515/9783110264043 - + EMAPA @@ -324622,7 +324612,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -324664,14 +324654,14 @@ https://doi.org/10.1515/9783110264043 organism substance - + - + this relationship may be too strong and may be weakened in future @@ -325922,7 +325912,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -325966,14 +325956,14 @@ https://doi.org/10.1515/9783110264043 epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -326574,7 +326564,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -326611,14 +326601,14 @@ https://doi.org/10.1515/9783110264043 abdomen - + - + MA @@ -326881,7 +326871,7 @@ https://doi.org/10.1515/9783110264043 - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -326919,14 +326909,14 @@ https://doi.org/10.1515/9783110264043 ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -326991,7 +326981,7 @@ https://doi.org/10.1515/9783110264043 - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -327028,14 +327018,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -327102,7 +327092,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327153,7 +327143,7 @@ https://doi.org/10.1515/9783110264043 mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -327166,7 +327156,7 @@ https://doi.org/10.1515/9783110264043 - + Bgee:AN @@ -327377,7 +327367,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327427,7 +327417,7 @@ https://doi.org/10.1515/9783110264043 proctodeum https://github.com/obophenotype/uberon/issues/685 - + @@ -327440,7 +327430,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -327513,7 +327503,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327554,7 +327544,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327634,11 +327624,11 @@ https://doi.org/10.1515/9783110264043 stomach https://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg - + - + @@ -327657,14 +327647,14 @@ https://doi.org/10.1515/9783110264043 - + absent in lampreys and hagfishes ISBN:0073040584 - + ISBN:0486692132 @@ -327758,7 +327748,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327807,7 +327797,7 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb https://upload.wikimedia.org/wikipedia/commons/9/91/Aorta_scheme.jpg - + @@ -327820,7 +327810,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -327900,7 +327890,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -328009,14 +327999,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + MA @@ -328212,7 +328202,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -328243,7 +328233,7 @@ https://doi.org/10.1515/9783110264043 - + The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. requires review for applicability to invertebrate structures, e.g. synganglion @@ -328307,11 +328297,11 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb - + - + @@ -328324,13 +328314,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + Bgee:AN @@ -328583,9 +328573,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -328610,7 +328600,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -328666,44 +328656,44 @@ https://doi.org/10.1515/9783110264043 cornea http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + - + MA - + MA - + FMA-isa - + definitional @@ -328893,9 +328883,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -328906,7 +328896,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -328963,44 +328953,44 @@ https://doi.org/10.1515/9783110264043 retina http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png - + - + - + - + - + FMA - + FMA - + FMA - + EHDAA2 @@ -329074,8 +329064,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -329111,24 +329101,24 @@ https://doi.org/10.1515/9783110264043 eye - + - + - + PMID:21062451 - + PMID:21062451 @@ -329305,7 +329295,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -329319,7 +329309,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -329386,14 +329376,14 @@ https://doi.org/10.1515/9783110264043 pleura http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png - + - + https://github.com/obophenotype/uberon/issues/86 @@ -329568,7 +329558,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -329637,14 +329627,14 @@ https://doi.org/10.1515/9783110264043 pons http://upload.wikimedia.org/wikipedia/commons/3/36/Gray768.png - + - + neuronames @@ -329713,8 +329703,8 @@ https://doi.org/10.1515/9783110264043 - - + + An intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination. penile phallic @@ -329750,11 +329740,11 @@ https://doi.org/10.1515/9783110264043 penis http://upload.wikimedia.org/wikipedia/commons/8/87/Labelled_flaccid_penis.jpg - + - + @@ -329767,13 +329757,13 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia - + EHDAA2 @@ -331084,7 +331074,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -331154,14 +331144,14 @@ https://doi.org/10.1515/9783110264043 vas deferens http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg - + - + FMA @@ -331293,7 +331283,7 @@ https://doi.org/10.1515/9783110264043 - + Tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Cuticles are non-homologous, differing in their origin, structure and chemical composition[WP]. cuticular BTO:0001600 @@ -331308,14 +331298,14 @@ https://doi.org/10.1515/9783110264043 EDITOR_NOTE TODO - check cuticle vs exoskeleton. Note that GO has a very generic definition of cuticle. See also arthropod-anatomy ontology. Note in ncit Cuticle is a plant part cuticle - + - + Rieger - Evolution of the Cuticle in the Lower Eumetazoa @@ -332454,7 +332444,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -332521,14 +332511,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -332638,7 +332628,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -332693,7 +332683,7 @@ https://doi.org/10.1515/9783110264043 central nervous system - + @@ -332707,7 +332697,7 @@ https://doi.org/10.1515/9783110264043 - + Bgee:AN @@ -332934,7 +332924,7 @@ https://doi.org/10.1515/9783110264043 - + A nerve that transmits from sensory receptors on the surface of the body to the central nervous system. AEO:0000201 EHDAA2:0003200 @@ -332949,14 +332939,14 @@ https://doi.org/10.1515/9783110264043 sensory nerve - + - + AEO @@ -333112,8 +333102,8 @@ https://doi.org/10.1515/9783110264043 - - + + A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. consider splitting class One of the extraembryonic fetal membranes that balloons out from the fetal midgut. [TFD][VHOG] @@ -333144,11 +333134,11 @@ https://doi.org/10.1515/9783110264043 yolk sac http://upload.wikimedia.org/wikipedia/commons/1/17/Gray22.png - + - + @@ -333167,13 +333157,13 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0073040584 - + ISBN:0073040584 @@ -333332,7 +333322,7 @@ https://doi.org/10.1515/9783110264043 - + A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]. A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNYX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx)[MESH:A03.867]. Anatomical cavity bounded by the derivatives of the branchial arches.[AAO] @@ -333374,14 +333364,14 @@ https://doi.org/10.1515/9783110264043 Consider generalizing to deuterostome pharynx chordate pharynx - + - + EHDAA2 @@ -333700,7 +333690,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -333737,14 +333727,14 @@ https://doi.org/10.1515/9783110264043 hindgut http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png - + - + Wikipedia @@ -334000,15 +333990,15 @@ https://doi.org/10.1515/9783110264043 - + - - + + @@ -334062,15 +334052,15 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb - + - + - + @@ -334084,19 +334074,19 @@ https://doi.org/10.1515/9783110264043 - + MA - + EHDAA2 - + ISBN:0073040584 @@ -334196,7 +334186,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -334243,7 +334233,7 @@ https://doi.org/10.1515/9783110264043 ventral pancreatic duct http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png - + @@ -334256,7 +334246,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -334341,7 +334331,7 @@ https://doi.org/10.1515/9783110264043 - + A zone of skin that is part of a back [Automatically generated definition]. EMAPA:36392 FMA:10462 @@ -334358,7 +334348,7 @@ https://doi.org/10.1515/9783110264043 EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region skin of back - + @@ -334371,7 +334361,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -334405,9 +334395,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]. not homologous to the external carotid of zebrafish (Goodrich, 1958) - http://zfish.nichd.nih.gov/zfatlas/Intro%20Page/comparative.html; check XAO @@ -334440,15 +334430,15 @@ https://doi.org/10.1515/9783110264043 https://sourceforge.net/tracker/?func=detail&aid=3486863&group_id=76834&atid=1127722 http://upload.wikimedia.org/wikipedia/commons/1/13/External_carotid_a.gif - + - + - + @@ -334461,19 +334451,19 @@ https://doi.org/10.1515/9783110264043 - + FMA - + EHDAA2 - + FMA @@ -334790,14 +334780,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -334838,11 +334828,11 @@ https://doi.org/10.1515/9783110264043 pericardial cavity - + - + @@ -334855,13 +334845,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + Wikipedia @@ -334934,7 +334924,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -334966,14 +334956,14 @@ https://doi.org/10.1515/9783110264043 endocardium of ventricle - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -335111,7 +335101,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -335139,14 +335129,14 @@ https://doi.org/10.1515/9783110264043 myocardium of ventricle - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -335657,7 +335647,7 @@ https://doi.org/10.1515/9783110264043 - + The second vertebral bone in the vertebral column. Vertebra that is posteriorly adjacent to vertebra 1.[TAO] @@ -335693,14 +335683,14 @@ https://doi.org/10.1515/9783110264043 vertebral bone 2 - + - + FMA @@ -336001,7 +335991,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -336018,7 +336008,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -336064,24 +336054,24 @@ https://doi.org/10.1515/9783110264043 diaphragm - + - + - + PMID:23586979 - + definitional @@ -336380,7 +336370,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -336461,14 +336451,14 @@ https://doi.org/10.1515/9783110264043 vertebral column - + - + cjm @@ -337155,7 +337145,7 @@ https://doi.org/10.1515/9783110264043 - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -337180,14 +337170,14 @@ https://doi.org/10.1515/9783110264043 mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -337302,7 +337292,7 @@ https://doi.org/10.1515/9783110264043 - + In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. BTO:0002783 @@ -337325,14 +337315,14 @@ https://doi.org/10.1515/9783110264043 superior mesenteric vein http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png - + - + Wikipedia:Vitelline_vein @@ -337374,7 +337364,7 @@ https://doi.org/10.1515/9783110264043 - + A vein that drains the pelvis and lower limbs into the inferior vena cava. In human anatomy, the common iliac veins are formed by the external iliac veins and internal iliac veins and together, in the abdomen at the level of the fifth lumbar vertebrae, form the inferior vena cava. They drain blood from the pelvis and lower limbs. Both common iliac veins are accompanied along their course by common iliac arteries. @@ -337397,7 +337387,7 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb https://upload.wikimedia.org/wikipedia/commons/6/65/Iliac_veins.gif - + @@ -337410,7 +337400,7 @@ https://doi.org/10.1515/9783110264043 - + FMA-abduced-lr @@ -337719,7 +337709,7 @@ https://doi.org/10.1515/9783110264043 - + Vein that carries blood away from the liver[ZFA]. todo - add developmental relationships for other taxa @@ -337750,14 +337740,14 @@ https://doi.org/10.1515/9783110264043 hepatic vein http://upload.wikimedia.org/wikipedia/commons/6/61/Gray1121.png - + - + FMA-abduced-lr @@ -338141,7 +338131,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -338177,7 +338167,7 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png - + @@ -338190,7 +338180,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -338238,7 +338228,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -338293,7 +338283,7 @@ https://doi.org/10.1515/9783110264043 colon - + @@ -338307,7 +338297,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -338372,7 +338362,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity. BTO:0000645 @@ -338404,7 +338394,7 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb - + @@ -338417,7 +338407,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -338522,7 +338512,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -338576,7 +338566,7 @@ https://doi.org/10.1515/9783110264043 pyloric antrum http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg - + @@ -338589,7 +338579,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -339093,7 +339083,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -339110,7 +339100,7 @@ https://doi.org/10.1515/9783110264043 portal lobule - + @@ -339123,7 +339113,7 @@ https://doi.org/10.1515/9783110264043 - + MA MP @@ -339147,7 +339137,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -339173,14 +339163,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001172 hepatic acinus - + - + cjm @@ -339416,16 +339406,16 @@ https://doi.org/10.1515/9783110264043 - - - + + + - + @@ -339454,19 +339444,19 @@ https://doi.org/10.1515/9783110264043 common hepatic duct http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg - + - + - + - + @@ -339479,25 +339469,25 @@ https://doi.org/10.1515/9783110264043 - + MA - + Wikipedia - + Wikipedia - + definitional @@ -339760,7 +339750,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -339802,14 +339792,14 @@ https://doi.org/10.1515/9783110264043 peritoneal cavity - + - + Wikipedia @@ -341932,8 +341922,8 @@ https://doi.org/10.1515/9783110264043 - - + + A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]. currently defined as equivalent to any submucosal gland in the duodenum. Said to be absent outside mammlian (Andrew 1959) but Ziswiler and Farner (1972) noted similar glands at the gastroduodenal junction of some birds @@ -341959,11 +341949,11 @@ https://doi.org/10.1515/9783110264043 duodenal gland - + - + @@ -341976,13 +341966,13 @@ https://doi.org/10.1515/9783110264043 - + FMA, modified - + unclear for Aves ISBN:9780521617147 @@ -342038,7 +342028,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -342084,7 +342074,7 @@ https://doi.org/10.1515/9783110264043 intestinal villus http://upload.wikimedia.org/wikipedia/commons/3/38/Small_intestine_low_mag.jpg - + @@ -342097,7 +342087,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -342210,7 +342200,7 @@ https://doi.org/10.1515/9783110264043 - + A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. BTO:0002782 @@ -342234,14 +342224,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + FMA/obol @@ -342389,14 +342379,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -342448,24 +342438,24 @@ https://doi.org/10.1515/9783110264043 renal pelvis https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg - + - + - + MA - + FMA @@ -342511,7 +342501,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -342548,14 +342538,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg - + - + FMA @@ -342584,11 +342574,11 @@ https://doi.org/10.1515/9783110264043 - + - - + + @@ -342627,7 +342617,7 @@ https://doi.org/10.1515/9783110264043 nephron tubule - + @@ -342636,18 +342626,18 @@ https://doi.org/10.1515/9783110264043 - + - + - + GO MA ZFA @@ -342661,13 +342651,13 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + checkme @@ -342708,7 +342698,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -342756,14 +342746,14 @@ https://doi.org/10.1515/9783110264043 collecting duct of renal tubule - + - + checkme GO @@ -343493,7 +343483,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -343525,7 +343515,7 @@ https://doi.org/10.1515/9783110264043 interlobular bile duct - + @@ -343539,7 +343529,7 @@ https://doi.org/10.1515/9783110264043 - + FMA MA MP @@ -343581,7 +343571,7 @@ https://doi.org/10.1515/9783110264043 - + An adventitia that is part of a ureter. EMAPA:28114 FMA:15892 @@ -343597,14 +343587,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001252 adventitia of ureter - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -343648,7 +343638,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a ureter [Automatically generated definition]. EMAPA:28841 @@ -343665,14 +343655,14 @@ https://doi.org/10.1515/9783110264043 lamina propria of ureter - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -343715,7 +343705,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -343726,7 +343716,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -343779,11 +343769,11 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urinary_Bladder.glb https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + @@ -343796,13 +343786,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + upper part of UG sinus @@ -344110,7 +344100,7 @@ https://doi.org/10.1515/9783110264043 - + A serous membrane that is part of a urinary bladder [Automatically generated definition]. TODO - check serosa/peritoneum EMAPA:28661 @@ -344133,14 +344123,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001260 serosa of urinary bladder - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -344429,7 +344419,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -344461,14 +344451,14 @@ https://doi.org/10.1515/9783110264043 pancreatic acinus - + - + FMA @@ -344517,9 +344507,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]. Organ which secretes a fluid containing enzymes that aid in the digestion of food.[AAO] @@ -344565,34 +344555,34 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Pancreas.glb https://upload.wikimedia.org/wikipedia/commons/7/7e/Blausen_0699_PancreasAnatomy2.png - + - + - + - + PMID:16417468 - + Wikipedia - + Wikipedia @@ -344657,7 +344647,7 @@ https://doi.org/10.1515/9783110264043 - + A trabecula that is part of a spleen. EMAPA:35808 @@ -344675,14 +344665,14 @@ https://doi.org/10.1515/9783110264043 trabecula of spleen - + - + FMA @@ -345267,7 +345257,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -345297,14 +345287,14 @@ https://doi.org/10.1515/9783110264043 liver parenchyma - + - + XAO @@ -345379,7 +345369,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -345429,14 +345419,14 @@ https://doi.org/10.1515/9783110264043 hepatic sinusoid - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -345501,8 +345491,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -345545,11 +345535,11 @@ https://doi.org/10.1515/9783110264043 intralobular bile duct - + - + @@ -345562,13 +345552,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + FMA @@ -345630,7 +345620,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -345643,7 +345633,7 @@ https://doi.org/10.1515/9783110264043 - + The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]. kidney terms require review for cross-vertebrate compatibility and developmental relationships. @@ -345676,24 +345666,24 @@ https://doi.org/10.1515/9783110264043 nephron http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + - + FMA - + Bgee:AN @@ -345762,7 +345752,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -345812,14 +345802,14 @@ https://doi.org/10.1515/9783110264043 endometrium https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg - + - + FMA @@ -345906,7 +345896,7 @@ https://doi.org/10.1515/9783110264043 - + Outer serosa layer of the uterus. TODO - check for parallel structure with peritoneum EMAPA:37792 @@ -345930,14 +345920,14 @@ https://doi.org/10.1515/9783110264043 serosa of uterus https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -346026,7 +346016,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -346056,14 +346046,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/1/13/Anteriorglanspenis.jpg https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png - + - + Bgee:AN @@ -346107,14 +346097,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -346169,24 +346159,24 @@ https://doi.org/10.1515/9783110264043 epididymis http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_testis_surface.jpg - + - + - + FMA - + Wikipedia @@ -346559,7 +346549,7 @@ https://doi.org/10.1515/9783110264043 - + Muscle (organ) which is a part of the pelvis. Examples: levator ani,. @@ -346577,7 +346567,7 @@ https://doi.org/10.1515/9783110264043 muscle of pelvis - + @@ -346589,7 +346579,7 @@ https://doi.org/10.1515/9783110264043 - + FMAdef @@ -346985,7 +346975,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -347030,14 +347020,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/4/49/Seminiferous_tubule_and_sperm_low_mag.jpg http://upload.wikimedia.org/wikipedia/commons/6/6a/Gray1145.png - + - + Wikipedia @@ -347116,7 +347106,7 @@ https://doi.org/10.1515/9783110264043 - + The anus and surrounding regions. Encompasses both internal and external regions, where present. Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG] EFO:0000847 @@ -347142,14 +347132,14 @@ https://doi.org/10.1515/9783110264043 https://github.com/obophenotype/uberon/issues/507 http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png - + - + cjm @@ -348013,7 +348003,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348024,7 +348014,7 @@ https://doi.org/10.1515/9783110264043 - + Skeletal element that is composed of bone tissue. @@ -348074,14 +348064,14 @@ https://doi.org/10.1515/9783110264043 bone element - + - + VSAO-modified @@ -348279,7 +348269,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348323,14 +348313,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + EHDAA2 @@ -348385,7 +348375,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a pelvic girdle [Automatically generated definition]. Note that in MA, this is a subclass of pelvis muscle; in FMA this is a hindlimb muscle, but recall in FMA hindlimb includes the girdle. UBERON:0003271 @@ -348407,14 +348397,14 @@ https://doi.org/10.1515/9783110264043 muscle of pelvic girdle - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -348484,7 +348474,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348532,14 +348522,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + left arch 4 in human embryology.ch @@ -348603,7 +348593,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348639,7 +348629,7 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + @@ -348652,7 +348642,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -348791,7 +348781,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348840,14 +348830,14 @@ https://doi.org/10.1515/9783110264043 abdominal aorta http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png - + - + FMA @@ -349029,7 +349019,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -349067,7 +349057,7 @@ https://doi.org/10.1515/9783110264043 common carotid artery plus branches http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg - + @@ -349080,7 +349070,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -349158,8 +349148,8 @@ https://doi.org/10.1515/9783110264043 - - + + One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta. Developmental relationships should be added (intersegmental artery and right dorsal aorta in EHDAA2, occipitovertebral artery in XAO) @@ -349197,24 +349187,24 @@ https://doi.org/10.1515/9783110264043 subclavian artery http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg - + - + - + EHDAA2 - + EHDAA2 @@ -349403,7 +349393,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -349458,14 +349448,14 @@ https://doi.org/10.1515/9783110264043 digestive tract - + - + NCBIBook:NBK10107 @@ -349989,7 +349979,7 @@ https://doi.org/10.1515/9783110264043 - + The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. BTO:0000654 @@ -350012,7 +350002,7 @@ https://doi.org/10.1515/9783110264043 ciliary muscle http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png - + @@ -350031,7 +350021,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -350155,10 +350145,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + A sphincter muscle that is part of the iris. In humans, it functions to constrict the pupil in bright light or during accommodation. Its dimensions are about 0.75 mm wide by 0.15 mm thick. It is controlled by parasympathetic fibers that originate from the Edinger-Westphal nucleus, travel along the oculomotor nerve (CN III), synapse in the ciliary ganglion, and then enter the eye via the short ciliary nerves. Initially, all the myocytes are of the smooth muscle type, but much later in life, so that ultimately most cells are of the striated muscle type. [WP,unvetted] WP says: It is found in vertebrates and some cephalopods; this class refers to the vertebrate structure @@ -350193,19 +350183,19 @@ https://doi.org/10.1515/9783110264043 sphincter pupillae http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png - + - + - + - + @@ -350218,27 +350208,27 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0781772214 - + encircles iris dbpedia - + encircles iris dbpedia - + dbpedia @@ -350351,10 +350341,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]. It is innervated by the sympathetic system, which acts by releasing noradrenaline, which acts on alpha1-receptors. Thus, when presented with a threatening stimuli that activates the fight-or-flight response, this innervation dilates the iris, thus temporarily letting more light reach the retina @@ -350391,19 +350381,19 @@ https://doi.org/10.1515/9783110264043 dilatator pupillae http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png - + - + - + - + @@ -350416,27 +350406,27 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0781772214 - + outer margins of iris dbpedia - + inner margins of iris dbpedia - + dbpedia @@ -351130,10 +351120,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + The first major branch of the abdominal aorta. EHDAA2:0004519 @@ -351165,44 +351155,44 @@ https://doi.org/10.1515/9783110264043 celiac artery http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png - + - + - + - + - + ISBN:0073040584 - + ISBN:0073040584 - + ISBN:0073040584 - + ISBN:0073040584 @@ -351323,7 +351313,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -351385,14 +351375,14 @@ https://doi.org/10.1515/9783110264043 trigeminal nerve https://upload.wikimedia.org/wikipedia/commons/9/99/Gray778_Trigeminal.png - + - + Wikipedia @@ -351677,7 +351667,7 @@ https://doi.org/10.1515/9783110264043 - + The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]. Vein which collects blood from muscles of the head and drains into the external jugular vein.[AAO] @@ -351701,14 +351691,14 @@ https://doi.org/10.1515/9783110264043 facial vein http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png - + - + FMA @@ -351790,7 +351780,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -351851,7 +351841,7 @@ https://doi.org/10.1515/9783110264043 trigeminal ganglion http://upload.wikimedia.org/wikipedia/commons/6/69/Gray776.png - + @@ -351864,7 +351854,7 @@ https://doi.org/10.1515/9783110264043 - + Bgee:AN @@ -351988,11 +351978,11 @@ https://doi.org/10.1515/9783110264043 - - - - - + + + + + @@ -352023,23 +352013,23 @@ https://doi.org/10.1515/9783110264043 occipital bone http://upload.wikimedia.org/wikipedia/commons/2/27/Gray194.png - + - + - + - + - + @@ -352052,32 +352042,32 @@ https://doi.org/10.1515/9783110264043 - + FMA - + basi paired exo and supra occipital bones MA-modified - + interparietal (postparietal) - + WP - + PMID:11523816 @@ -352139,10 +352129,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended. part of viscerocranium (facial skeleton) in FMA @@ -352171,19 +352161,19 @@ https://doi.org/10.1515/9783110264043 sphenoid bone http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg - + - + - + - + @@ -352196,25 +352186,25 @@ https://doi.org/10.1515/9783110264043 - + orbito pre and basi sphenoid - + pterygoid process - + alisphenoid - + cjm @@ -352283,7 +352273,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -352319,7 +352309,7 @@ https://doi.org/10.1515/9783110264043 ethmoid bone http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg - + @@ -352332,7 +352322,7 @@ https://doi.org/10.1515/9783110264043 - + definitional @@ -352415,7 +352405,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -352448,14 +352438,14 @@ https://doi.org/10.1515/9783110264043 orbit of skull - + - + FMA-abduced-lr @@ -352632,7 +352622,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -352698,14 +352688,14 @@ https://doi.org/10.1515/9783110264043 jaw skeleton - + - + cjm @@ -352915,7 +352905,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -352950,14 +352940,14 @@ https://doi.org/10.1515/9783110264043 lower jaw region http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png - + - + Wikipedia:Mandibular_prominence @@ -353145,7 +353135,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -353170,14 +353160,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001731 cavity of pharynx - + - + XAO @@ -353456,7 +353446,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -353499,14 +353489,14 @@ https://doi.org/10.1515/9783110264043 iris - + - + XAO @@ -353585,7 +353575,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -353637,14 +353627,14 @@ https://doi.org/10.1515/9783110264043 corneal epithelium http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + ISBN:0781772214 @@ -353741,15 +353731,15 @@ https://doi.org/10.1515/9783110264043 - - + + - + @@ -353791,34 +353781,34 @@ https://doi.org/10.1515/9783110264043 sclera http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + FMA - + ZFA - + ISBN:0781772214 @@ -353869,7 +353859,7 @@ https://doi.org/10.1515/9783110264043 - + A skeletal muscle organ that is part of the trunk region. Note that this class excludes smooth muscle elements in the trunk region, such as the internal anal sphincter. This appears to be consistent with other ontologies such as FMA and ZFA which appear to only include skeletal muscles here. In fact the MA class 'trunk muscle' is classified as a 'set of skeletal muscles'. Many ontologies do not appear to have a coherent distinction between an individual muscle and the musculature (i.e. the set of muscles in a region), so we group all together here. @@ -353894,14 +353884,14 @@ https://doi.org/10.1515/9783110264043 skeletal muscle of trunk - + - + prolog @@ -353972,7 +353962,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -354011,14 +354001,14 @@ https://doi.org/10.1515/9783110264043 ciliary body http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + ISBN:0781772214 @@ -354066,14 +354056,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -354136,24 +354126,24 @@ https://doi.org/10.1515/9783110264043 optic choroid http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + MA - + Wikipedia @@ -354254,7 +354244,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -354303,14 +354293,14 @@ https://doi.org/10.1515/9783110264043 substantia propria of cornea http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + cjm ISBN:0781772214 Wikipedia @@ -354378,15 +354368,15 @@ https://doi.org/10.1515/9783110264043 - + - - - + + + A double layer covering the ciliary body that produces aqueous humor. BTO:0001770 @@ -354406,15 +354396,15 @@ https://doi.org/10.1515/9783110264043 ciliary epithelium - + - + - + @@ -354427,19 +354417,19 @@ https://doi.org/10.1515/9783110264043 - + MA - + MP - + Wikipedia @@ -354874,7 +354864,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -354910,14 +354900,14 @@ https://doi.org/10.1515/9783110264043 aqueous humor of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + FMA def states A and P located_in in EHDAA2 VHOG @@ -355047,8 +355037,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -355081,24 +355071,24 @@ https://doi.org/10.1515/9783110264043 anterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png - + - + - + FMA - + cjm @@ -355150,8 +355140,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -355181,24 +355171,24 @@ https://doi.org/10.1515/9783110264043 posterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + FMA - + cjm @@ -355386,7 +355376,7 @@ https://doi.org/10.1515/9783110264043 - + The elastic, clear, membrane-like structure, that is outer most layer of the lens. The transparent membrane which surrounds the lens of the eye. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG] (...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod. (...) A watery aqueous humor fills the spaces in the eye in front of the lens (...) (reference 2).[well established][VHOG] @@ -355412,14 +355402,14 @@ https://doi.org/10.1515/9783110264043 capsule of lens http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png - + - + EHDAA2 @@ -355595,7 +355585,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -355634,14 +355624,14 @@ https://doi.org/10.1515/9783110264043 sympathetic ganglion http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png - + - + DOI:10.1101/gr.157586.113 ISBN:0073040584 @@ -355705,7 +355695,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -355716,7 +355706,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -355759,11 +355749,11 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/9/90/Lips.JPG http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg - + - + @@ -355776,7 +355766,7 @@ https://doi.org/10.1515/9783110264043 - + BTO FMA-implicit VHOG @@ -355785,7 +355775,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -356169,14 +356159,14 @@ https://doi.org/10.1515/9783110264043 - + - + The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. developmental relationships need revised @@ -356229,24 +356219,24 @@ https://doi.org/10.1515/9783110264043 midbrain http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG - + - + - + definitional - + Bgee:AN @@ -356467,7 +356457,7 @@ https://doi.org/10.1515/9783110264043 - + Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]. Anterior part of the hindbrain ventral to the cerebellum[BIRNLEX:965]. @@ -356503,14 +356493,14 @@ https://doi.org/10.1515/9783110264043 metencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -356772,7 +356762,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of a small intestine [Automatically generated definition]. Intestinal epithelium which lines the lumen of the mid intestine.[TAO] BTO:0001258 @@ -356797,14 +356787,14 @@ https://doi.org/10.1515/9783110264043 epithelium of small intestine - + - + FMA @@ -357202,7 +357192,7 @@ https://doi.org/10.1515/9783110264043 - + Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. Together, our results reveal a shared basic organization in the tegmental domains of the diencephalon and midbrain of developing lamprey, indicating early appearance of the domain in vertebrate phylogeny.[well established][VHOG] @@ -357243,14 +357233,14 @@ https://doi.org/10.1515/9783110264043 midbrain tegmentum http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png - + - + ZFA @@ -357562,7 +357552,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -357621,14 +357611,14 @@ https://doi.org/10.1515/9783110264043 bile - + - + 0.3% in humans @@ -357839,7 +357829,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a esophagus [Automatically generated definition]. EMAPA:26987 FMA:63050 @@ -357868,14 +357858,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001974 lamina propria of esophagus - + - + FMA @@ -358107,7 +358097,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -358148,14 +358138,14 @@ https://doi.org/10.1515/9783110264043 epithelium of esophagus - + - + FMA @@ -358469,8 +358459,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -358483,7 +358473,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -358542,34 +358532,34 @@ https://doi.org/10.1515/9783110264043 blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -358936,10 +358926,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. Phylogenetic analyses of the concatenated data set using maximum parsimony, maximum likelihood and distance based (neighbour joining) methods all converged on a nearly identical, well supported topology defining four principal eutherian lineages. The results affirm monophyly of traditional placental orders (except Artiodactyla and Insectivora), and also support some previously proposed, as well as new, superordinal clades.[well established][VHOG] @@ -358976,44 +358966,44 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/f/f1/Placenta.svg https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb - + - + - + - + - + https://github.com/obophenotype/uberon/issues/1376 - + ISBN:0073040584 - + Wikipedia - + ISBN:0073040584 @@ -359238,9 +359228,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.. @@ -359282,35 +359272,35 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png - + - + - + - + Wikipedia - + EHDAA2 XAO - + EHDAA2 @@ -359809,7 +359799,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -359828,7 +359818,7 @@ https://doi.org/10.1515/9783110264043 - + The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. @@ -359879,25 +359869,25 @@ https://doi.org/10.1515/9783110264043 hindbrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + - + modified-source-relation ABA - + Bgee:AN @@ -360268,7 +360258,7 @@ https://doi.org/10.1515/9783110264043 - + The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]. @@ -360299,14 +360289,14 @@ https://doi.org/10.1515/9783110264043 pontine raphe nucleus - + - + Wikipedia @@ -360390,7 +360380,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -360493,14 +360483,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb - + - + some species only have a single lung @@ -360819,9 +360809,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles. assume spelling error for ncit EHDAA2:0004143 @@ -360839,15 +360829,15 @@ https://doi.org/10.1515/9783110264043 truncus arteriosus - + - + - + @@ -360866,19 +360856,19 @@ https://doi.org/10.1515/9783110264043 - + MA - + EHDAA2 - + EHDAA2 @@ -360909,7 +360899,7 @@ https://doi.org/10.1515/9783110264043 - + The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves.[TAO] relationship loss: develops_from endocardial ring (TAO:0005072)[TAO] @@ -360941,14 +360931,14 @@ https://doi.org/10.1515/9783110264043 endocardial cushion http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png - + - + ZFA @@ -361031,14 +361021,14 @@ https://doi.org/10.1515/9783110264043 - + - + The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart. Heart region collecting blood from the paired common cardinal veins and delivering to the atrium. One of four components of the heart. The sinus venosus also acts as a pacemaker and is the first to contract. Kimmel et al, 1995.[TAO] Part of the circulatory system which receives blood from the systemic veins and contracts to pump the blood into the atrium of the heart.[AAO] @@ -361073,24 +361063,24 @@ https://doi.org/10.1515/9783110264043 sinus venosus http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png - + - + - + VHOG - + Bgee:AN @@ -361193,7 +361183,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -361230,7 +361220,7 @@ https://doi.org/10.1515/9783110264043 - + The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. Consider adding a layer-of-skin grouping class for all skin layers @@ -361270,24 +361260,24 @@ https://doi.org/10.1515/9783110264043 dermis http://upload.wikimedia.org/wikipedia/commons/2/23/EpidermisPainted.svg - + - + - + FMA - + definitional @@ -361345,7 +361335,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -361364,7 +361354,7 @@ https://doi.org/10.1515/9783110264043 - + Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO] @@ -361400,24 +361390,24 @@ https://doi.org/10.1515/9783110264043 hypodermis http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg - + - + - + ZFA - + FMA-modified @@ -361867,8 +361857,8 @@ https://doi.org/10.1515/9783110264043 - - + + A cardiac ventricle that is in the right side of the heart. The muscular chamber on the right and in front of the left ventricle. It generally receives venous blood from the right atrium and conveys it into the pulmonary artery. [(1988)_Dorian_AF, Amsterdam, Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B._Anatomy, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier's_Encyclopaedic_Dictionary_of_Medicine][VHOG] @@ -361901,24 +361891,24 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + - + PMID:17276708 - + cjm @@ -362109,7 +362099,7 @@ https://doi.org/10.1515/9783110264043 - + Cardiac chamber through which blood leaves the heart. A chamber of the heart that receives blood from one or more atria and pumps it by muscular contraction into the arteries.[AAO] One of four heart chambers.[TAO] @@ -362148,14 +362138,14 @@ https://doi.org/10.1515/9783110264043 cardiac ventricle - + - + Bgee:AN @@ -362236,7 +362226,7 @@ https://doi.org/10.1515/9783110264043 - + A cardiac ventricle that is in the left side of the heart. Thick-walled muscular chamber constituting the left border and apex of the heart. It receives oxygenated blood from the left atrium through the mitral orifice and send it off into the aorta. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG] @@ -362270,14 +362260,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + GO @@ -362922,7 +362912,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -362968,14 +362958,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Skin.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.3/3d-vh-f-skin.glb - + - + Wikipathways:WP2062 @@ -363324,7 +363314,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -363376,14 +363366,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spleen.glb https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg - + - + multiple sources - true spleen appear in jawed vertebrates @@ -363441,22 +363431,22 @@ https://doi.org/10.1515/9783110264043 - + - + - - + + @@ -363536,19 +363526,19 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Liver.glb https://upload.wikimedia.org/wikipedia/commons/6/64/Leber_Schaf.jpg - + - + - + - + @@ -363563,25 +363553,25 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + ZFA-weakened - + EHDAA2 - + http://www.stembook.org/node/512 @@ -363813,7 +363803,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -363884,7 +363874,7 @@ https://doi.org/10.1515/9783110264043 https://upload.wikimedia.org/wikipedia/commons/b/b1/GallbladderAnatomy-en.svg https://upload.wikimedia.org/wikipedia/commons/f/f4/Abdomal_organs.svg - + @@ -363897,7 +363887,7 @@ https://doi.org/10.1515/9783110264043 - + definitional @@ -364264,7 +364254,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -364277,7 +364267,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -364328,24 +364318,24 @@ https://doi.org/10.1515/9783110264043 kidney - + - + - + FMA - + definitional @@ -364654,8 +364644,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -364699,11 +364689,11 @@ https://doi.org/10.1515/9783110264043 Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 pronephros - + - + @@ -364716,13 +364706,13 @@ https://doi.org/10.1515/9783110264043 - + OG - + ZFA @@ -364815,7 +364805,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -364854,14 +364844,14 @@ https://doi.org/10.1515/9783110264043 superior olivary complex http://upload.wikimedia.org/wikipedia/commons/4/46/Gray713.png - + - + NIFSTD @@ -364960,7 +364950,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -365018,14 +365008,14 @@ https://doi.org/10.1515/9783110264043 locus ceruleus http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png - + - + check ZFA NIFSTD @@ -365159,7 +365149,7 @@ https://doi.org/10.1515/9783110264043 - + Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703). @@ -365195,14 +365185,14 @@ https://doi.org/10.1515/9783110264043 superior salivatory nucleus http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray788.png - + - + definitional @@ -365337,7 +365327,7 @@ https://doi.org/10.1515/9783110264043 - + The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]. Layer that lines the lumen of the heart.[TAO] Part of the heart comprised of thin serous membrane, composed of endothelial tissue, that lines the interior of the heart.[AAO] @@ -365379,14 +365369,14 @@ https://doi.org/10.1515/9783110264043 endocardium http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png - + - + Bgee:AN @@ -365867,7 +365857,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -365927,7 +365917,7 @@ https://doi.org/10.1515/9783110264043 integument - + @@ -365940,7 +365930,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -366207,7 +366197,7 @@ https://doi.org/10.1515/9783110264043 - + Vasculature that is part of the eye region. not part of the eye in ZFA. Note this changed to a blood vessel in ZFA @@ -366230,14 +366220,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + ISBN:0781772214 @@ -366296,7 +366286,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -366337,14 +366327,14 @@ https://doi.org/10.1515/9783110264043 musculoskeletal system - + - + check ctenophore @@ -366634,7 +366624,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -366647,8 +366637,8 @@ https://doi.org/10.1515/9783110264043 - - + + Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). TODO - add superclass to unify with VNC? @@ -366707,34 +366697,34 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spinal_Cord.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spinal_Cord.glb - + - + - + - + ZFA - + definitional - + definitional @@ -366926,7 +366916,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -366977,14 +366967,14 @@ https://doi.org/10.1515/9783110264043 ventral horn of spinal cord - + - + FMA-abduced-lr @@ -367283,7 +367273,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -367313,14 +367303,14 @@ https://doi.org/10.1515/9783110264043 dorsal mesentery http://upload.wikimedia.org/wikipedia/commons/8/85/Gray985.png - + - + EHDAA2 @@ -367799,7 +367789,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -367840,14 +367830,14 @@ https://doi.org/10.1515/9783110264043 EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct coelemic cavity lumen - + - + definitional @@ -367953,7 +367943,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a back [Automatically generated definition]. EMAPA:35161 @@ -367967,14 +367957,14 @@ https://doi.org/10.1515/9783110264043 muscle of back - + - + prolog @@ -368190,9 +368180,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -368249,15 +368239,15 @@ https://doi.org/10.1515/9783110264043 notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -368276,19 +368266,19 @@ https://doi.org/10.1515/9783110264043 - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -368373,7 +368363,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -368384,7 +368374,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -368436,11 +368426,11 @@ https://doi.org/10.1515/9783110264043 somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -368453,13 +368443,13 @@ https://doi.org/10.1515/9783110264043 - + GOTAX:0000352 - + ZFA @@ -368904,12 +368894,12 @@ https://doi.org/10.1515/9783110264043 - - - - - - + + + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -368949,66 +368939,66 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -369381,15 +369371,15 @@ https://doi.org/10.1515/9783110264043 - - + + - + A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart. External layer of the heart.[TAO] @@ -369419,34 +369409,34 @@ https://doi.org/10.1515/9783110264043 EDITOR_NOTE TODO - check links with UBERON:0002425 visceral serous pericardium. develops from proepicardium. WP:Epicardium -- When considered as a part of the pericardium, it is the inner layer, or visceral pericardium, continuous with the serous layer. epicardium - + - + - + - + multiple - + FMA-inferred - + FMA @@ -369633,11 +369623,11 @@ https://doi.org/10.1515/9783110264043 - - - - - + + + + + @@ -369674,23 +369664,23 @@ https://doi.org/10.1515/9783110264043 conducting system of heart - + - + - + - + - + @@ -369703,31 +369693,31 @@ https://doi.org/10.1515/9783110264043 - + FMA - + FMA - + FMA - + FMA - + FMA @@ -369794,7 +369784,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -369858,7 +369848,7 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/d/d2/Sinoatrial_node_low_mag.jpg http://upload.wikimedia.org/wikipedia/commons/d/de/Sinoatrial_node_2_low_mag.jpg - + @@ -369871,7 +369861,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -370154,8 +370144,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -370185,11 +370175,11 @@ https://doi.org/10.1515/9783110264043 cardiac Purkinje fiber http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png - + - + @@ -370202,7 +370192,7 @@ https://doi.org/10.1515/9783110264043 - + https://github.com/obophenotype/uberon/issues/1785 https://orcid.org/0000-0001-5208-3432 https://orcid.org/0000-0002-9791-0064 @@ -370210,7 +370200,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -370357,7 +370347,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -370370,7 +370360,7 @@ https://doi.org/10.1515/9783110264043 - + Serous membrane which is divided into parietal and visceral serous pericardium. EMAPA:19030 FMA:9582 @@ -370384,24 +370374,24 @@ https://doi.org/10.1515/9783110264043 serous pericardium - + - + - + FMA - + FMA @@ -370442,7 +370432,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -370480,14 +370470,14 @@ https://doi.org/10.1515/9783110264043 peritoneum http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png - + - + MP @@ -370540,14 +370530,14 @@ https://doi.org/10.1515/9783110264043 - + - + Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]. most superficial part of pericardium; continuous with the outer adventitial layer of the neighboring great blood vessels. [Wikipedia:Pericardium] EMAPA:19029 @@ -370563,11 +370553,11 @@ https://doi.org/10.1515/9783110264043 fibrous pericardium - + - + @@ -370580,13 +370570,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + WP @@ -370798,7 +370788,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -370856,14 +370846,14 @@ https://doi.org/10.1515/9783110264043 bone marrow http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg - + - + FMA MA @@ -370935,8 +370925,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -370975,24 +370965,24 @@ https://doi.org/10.1515/9783110264043 defined generically so could in theory encompass FBbt:00003260 'skeletal muscle of head', or the muscle of a starfish Aristotle's lantern, but we restrict this to craniates. Skeletal muscles of the head originate from the non-segmented head mesoderm (Noden, 1983; Wachtler et al., 1984) cranial muscle - + - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships - + EHDAA2-abduced @@ -371067,7 +371057,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle that is part of the cervical (neck) region. EMAPA:36050 @@ -371089,14 +371079,14 @@ https://doi.org/10.1515/9783110264043 muscle of neck - + - + prolog @@ -371154,7 +371144,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -371186,14 +371176,14 @@ https://doi.org/10.1515/9783110264043 muscle of abdomen - + - + prolog @@ -371451,14 +371441,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -371507,24 +371497,24 @@ https://doi.org/10.1515/9783110264043 hematopoietic system - + - + - + FMA - + definitional @@ -371580,15 +371570,15 @@ https://doi.org/10.1515/9783110264043 - + + - @@ -371635,25 +371625,25 @@ https://doi.org/10.1515/9783110264043 bile duct http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png - + - + - + EMAPA MA - + XAO @@ -371971,7 +371961,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -372016,14 +372006,14 @@ https://doi.org/10.1515/9783110264043 visceral pleura - + - + FMA @@ -372103,7 +372093,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -372149,14 +372139,14 @@ https://doi.org/10.1515/9783110264043 pleural cavity http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png - + - + Wikipedia @@ -372327,7 +372317,7 @@ https://doi.org/10.1515/9783110264043 - + A double-walled sac containing the heart and the roots of the great vessels. FMA:9868 RETIRED_EHDAA2:0001443 @@ -372341,14 +372331,14 @@ https://doi.org/10.1515/9783110264043 pericardial sac http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png - + - + FMA @@ -372372,7 +372362,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -372431,14 +372421,14 @@ https://doi.org/10.1515/9783110264043 pericardium http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png - + - + MA @@ -372631,7 +372621,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -372687,7 +372677,7 @@ https://doi.org/10.1515/9783110264043 autonomic nervous system http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png - + @@ -372700,7 +372690,7 @@ https://doi.org/10.1515/9783110264043 - + EMAPA MA NIFSTD @@ -372818,9 +372808,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -372851,15 +372841,15 @@ https://doi.org/10.1515/9783110264043 clitoris http://upload.wikimedia.org/wikipedia/commons/c/cf/Clitoris_anatomy_labeled-en.svg - + - + - + @@ -372872,19 +372862,19 @@ https://doi.org/10.1515/9783110264043 - + MA - + Wikipedia - + EHDAA2 Wikipedia @@ -373758,7 +373748,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues. consider including separate class for developmental structure (adult human is stratified; in EHDAA2 is unilaminar) The epithelium that lines the oral cavity. The oral epithelium epithelial cells with many short microvilli as well as mucous cells, rodlet cells and taste buds[ZFIN:ZDB-PUB-060921-12, ZFIN:ZDB-PUB-091204-24]. @@ -373785,14 +373775,14 @@ https://doi.org/10.1515/9783110264043 oral epithelium - + - + AAO-modified @@ -373855,8 +373845,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -373884,24 +373874,24 @@ https://doi.org/10.1515/9783110264043 visceral serous pericardium - + - + - + cjm - + FMA @@ -374057,7 +374047,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -374103,7 +374093,7 @@ https://doi.org/10.1515/9783110264043 decidua http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray33.png - + @@ -374116,7 +374106,7 @@ https://doi.org/10.1515/9783110264043 - + maternal MA @@ -374203,7 +374193,7 @@ https://doi.org/10.1515/9783110264043 - + The mucous secreting gland associated with the mucuous membrane lining the uterus. simple or branched tubular @@ -374231,7 +374221,7 @@ https://doi.org/10.1515/9783110264043 endometrial gland http://upload.wikimedia.org/wikipedia/commons/2/28/Gray1169.png - + @@ -374244,7 +374234,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia:Tubular_gland @@ -374822,14 +374812,14 @@ https://doi.org/10.1515/9783110264043 - + - - + + @@ -374855,11 +374845,11 @@ https://doi.org/10.1515/9783110264043 iris epithelium - + - + @@ -374872,13 +374862,13 @@ https://doi.org/10.1515/9783110264043 - + MA - + MP @@ -374945,7 +374935,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -374973,14 +374963,14 @@ https://doi.org/10.1515/9783110264043 trabecula carnea - + - + WP @@ -375065,7 +375055,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -375099,7 +375089,7 @@ https://doi.org/10.1515/9783110264043 https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg - + @@ -375112,7 +375102,7 @@ https://doi.org/10.1515/9783110264043 - + VSAO @@ -375384,8 +375374,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -375411,11 +375401,11 @@ https://doi.org/10.1515/9783110264043 tunica media https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg - + - + @@ -375428,13 +375418,13 @@ https://doi.org/10.1515/9783110264043 - + cjm - + cjm @@ -375471,8 +375461,8 @@ https://doi.org/10.1515/9783110264043 - - + + The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]. the FMA class represents a more generic layer which is the superclass of the layer found in both blood vessels and lymph vessels (and also endocardium) - we should probably follow this structure the FMA class represents a structure which may have both epithelium and fibroelastic connective tissue as parts @@ -375497,11 +375487,11 @@ https://doi.org/10.1515/9783110264043 tunica intima https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg - + - + @@ -375514,13 +375504,13 @@ https://doi.org/10.1515/9783110264043 - + check for exceptions, e.g. capillaries - + ISBN:0073040584 @@ -375990,9 +375980,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO] A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down.[well established][VHOG] @@ -376028,15 +376018,15 @@ https://doi.org/10.1515/9783110264043 pharyngeal arch http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray41.png - + - + - + @@ -376049,19 +376039,19 @@ https://doi.org/10.1515/9783110264043 - + PMID:16313389 - + http://tolweb.org/Chordata/2499 - + PMID:16313389 @@ -376130,7 +376120,7 @@ https://doi.org/10.1515/9783110264043 - + Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. Do not merge with neurogenic placode Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons @@ -376150,7 +376140,7 @@ https://doi.org/10.1515/9783110264043 cranial placode - + @@ -376163,7 +376153,7 @@ https://doi.org/10.1515/9783110264043 - + PMID:11523831 PMID:22512454 @@ -377158,7 +377148,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -377177,7 +377167,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. consider adding class for organizer. Consider adding separate class for isthmus as a structure Lampreys also have an MHB [midbrain hindbrain boundary], expressing a similar repertoire of regulatory gene cognates as in gnathostomes.[well established][VHOG] @@ -377207,11 +377197,11 @@ https://doi.org/10.1515/9783110264043 midbrain-hindbrain boundary - + - + @@ -377225,13 +377215,13 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + ZFA @@ -377277,8 +377267,8 @@ https://doi.org/10.1515/9783110264043 - - + + A temporary epithelium that derives from the outer layer of the ectdoerm and is shed once the inner layer differentiates to form a true epidermis. The outermost epidermal layer covering the fish at embryonic stages; derived from the EVL and thought to eventually be replaced by the superficial stratum of the epidermis. Sometimes used synonymously with EVL. Le Guellec et al, 2004.[TAO] relationship type change: OBO_REL:part_of ectoderm (TAO:0000016) CHANGED TO: develops_from ectoderm (UBERON:0000924)[TAO] @@ -377307,11 +377297,11 @@ https://doi.org/10.1515/9783110264043 periderm - + - + @@ -377324,13 +377314,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + ZFA @@ -377496,7 +377486,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -377519,7 +377509,7 @@ https://doi.org/10.1515/9783110264043 - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -377544,14 +377534,14 @@ https://doi.org/10.1515/9783110264043 presomitic mesoderm - + - + Bgee:AN @@ -377611,8 +377601,8 @@ https://doi.org/10.1515/9783110264043 - - + + In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. Duct of the embryonic kidney, present bilaterally ventral to the somites and leading to the anal region where it empties separately from, and just posterior to the anus. Kimmel et al, 1995.[TAO] The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG] @@ -377636,11 +377626,11 @@ https://doi.org/10.1515/9783110264043 The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] pronephric duct - + - + @@ -377653,13 +377643,13 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia - + XAO @@ -377848,14 +377838,14 @@ https://doi.org/10.1515/9783110264043 - + - + A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue. TODO - check; developmental relationship to anterior hypoblast in ZFA? Axial hypoblast located anterior to the chorda mesoderm; the polster is its most anterior region. Kimmel et al, 1995.[TAO] @@ -377880,24 +377870,24 @@ https://doi.org/10.1515/9783110264043 prechordal plate - + - + - + ZFA - + PMID:16313393 @@ -377954,9 +377944,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -377998,34 +377988,34 @@ https://doi.org/10.1515/9783110264043 intermediate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + - + AAO - + EMAPA - + XAO @@ -378337,7 +378327,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -378375,7 +378365,7 @@ https://doi.org/10.1515/9783110264043 eye primordium - + @@ -378388,7 +378378,7 @@ https://doi.org/10.1515/9783110264043 - + PMID:16496288 XAO @@ -378450,8 +378440,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -378480,24 +378470,24 @@ https://doi.org/10.1515/9783110264043 optic cup - + - + - + ZFA - + ZFA @@ -378563,7 +378553,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -378604,7 +378594,7 @@ https://doi.org/10.1515/9783110264043 lens placode http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png - + @@ -378617,7 +378607,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -378686,7 +378676,7 @@ https://doi.org/10.1515/9783110264043 - + Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. Consider adding subclasses for male and female specific variants TODO - mesonephric portion of the nephric duct @@ -378724,7 +378714,7 @@ https://doi.org/10.1515/9783110264043 mesonephric duct http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + @@ -378737,7 +378727,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -378827,15 +378817,15 @@ https://doi.org/10.1515/9783110264043 - + - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -378867,34 +378857,34 @@ https://doi.org/10.1515/9783110264043 neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -379019,7 +379009,7 @@ https://doi.org/10.1515/9783110264043 - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -379048,7 +379038,7 @@ https://doi.org/10.1515/9783110264043 paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -379061,7 +379051,7 @@ https://doi.org/10.1515/9783110264043 - + Bgee:AN @@ -379130,8 +379120,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -379157,11 +379147,11 @@ https://doi.org/10.1515/9783110264043 epibranchial placode - + - + @@ -379175,13 +379165,13 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + EHDAA2-abduced @@ -379284,7 +379274,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -379328,7 +379318,7 @@ https://doi.org/10.1515/9783110264043 lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -379341,7 +379331,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 VHOG @@ -379425,7 +379415,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -379468,7 +379458,7 @@ https://doi.org/10.1515/9783110264043 myotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + @@ -379481,7 +379471,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2-abduced @@ -379544,7 +379534,7 @@ https://doi.org/10.1515/9783110264043 - + Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]. Post-cranial portion of the neural crest. Exact anatomical derivations not experimentally resolved in amphibians.[AAO] We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG] @@ -379564,14 +379554,14 @@ https://doi.org/10.1515/9783110264043 trunk neural crest - + - + ZFA @@ -379614,15 +379604,15 @@ https://doi.org/10.1515/9783110264043 - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO] @@ -379642,15 +379632,15 @@ https://doi.org/10.1515/9783110264043 heart primordium - + - + - + @@ -379663,19 +379653,19 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + ZFA - + XAO @@ -379813,8 +379803,8 @@ https://doi.org/10.1515/9783110264043 - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. Skeletogenic portion of somites.[AAO] The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] @@ -379842,11 +379832,11 @@ https://doi.org/10.1515/9783110264043 sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -379865,13 +379855,13 @@ https://doi.org/10.1515/9783110264043 - + VHOG:0000680 - + ZFA @@ -381200,8 +381190,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -381249,24 +381239,24 @@ https://doi.org/10.1515/9783110264043 chorion membrane http://upload.wikimedia.org/wikipedia/commons/5/51/Gray24.png - + - + - + Hymans - + ISBN:0073040584 @@ -381889,7 +381879,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -381917,14 +381907,14 @@ https://doi.org/10.1515/9783110264043 Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] metanephric mesenchyme - + - + ISBN:9780878932504 @@ -381988,14 +381978,14 @@ https://doi.org/10.1515/9783110264043 - - + + - - + + An extraembryonic structure that develops_from a syncytiotrophoblast and is part of a chorion. TODO - check EHDAA2:0001973 @@ -382004,24 +381994,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0003224 chorion syncytiotrophoblast - + - + - + EHDAA2 - + polar trophectoderm syncytiotrophoblast EHDAA2 @@ -382427,7 +382417,7 @@ https://doi.org/10.1515/9783110264043 - + A mesenchyme that is part of a chorion. TODO - check UBERON:0003423 @@ -382446,7 +382436,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0003265 chorionic mesenchyme - + @@ -382465,7 +382455,7 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0073040584 @@ -382673,8 +382663,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -382706,24 +382696,24 @@ https://doi.org/10.1515/9783110264043 skeleton of lower jaw - + - + - + EHDAA2 - + VHOG-modified @@ -382799,12 +382789,12 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -382831,7 +382821,7 @@ https://doi.org/10.1515/9783110264043 mesentery of stomach - + @@ -382844,7 +382834,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -383156,13 +383146,13 @@ https://doi.org/10.1515/9783110264043 - + - + Racemose mucous glands beneath the mucous membrane of the pharynx. BTO:0004849 EHDAA2:0001461 @@ -383175,14 +383165,14 @@ https://doi.org/10.1515/9783110264043 pharyngeal gland - + - + BTO @@ -383291,7 +383281,7 @@ https://doi.org/10.1515/9783110264043 - + A blood island that is part of a mesoderm. in EHDAA2, gives rise to blood and dorsal aorta UBERON:0003305 @@ -383304,7 +383294,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0003304 mesoderm blood island - + @@ -383317,7 +383307,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -383416,7 +383406,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a developing camera-type eye. TODO - change mesenchyme relationships to precursor_of EHDAA2:0000485 @@ -383428,14 +383418,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003314 eye mesenchyme - + - + EHDAA2 @@ -383628,7 +383618,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a developing upper jaw [Automatically generated definition]. EHDAA2:0002124 EHDAA:8031 @@ -383641,14 +383631,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003323 mesenchyme of upper jaw - + - + EHDAA2 @@ -383699,7 +383689,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a developing lower jaw [Automatically generated definition]. EHDAA2:0001024 EHDAA:8003 @@ -383712,14 +383702,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003324 mesenchyme of lower jaw - + - + EHDAA2 @@ -385111,15 +385101,15 @@ https://doi.org/10.1515/9783110264043 - + + - An epithelium that is part of a pharynx [Automatically generated definition]. Epithelium lining the pharynx consisting largely of simple columnar epithelium with a short segment (1mm) of stratified squamous epithelium on the ventral side. Chen et al, 2007.[TAO] BSA:0000112 @@ -385139,24 +385129,24 @@ https://doi.org/10.1515/9783110264043 pharyngeal epithelium - + - + - + ZFA - + ZFA @@ -385208,12 +385198,12 @@ https://doi.org/10.1515/9783110264043 - + - + An epithelium that is part of a midgut. BTO:0005053 EHDAA2:0001195 @@ -385226,14 +385216,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003352 epithelium of midgut - + - + BTO @@ -385526,7 +385516,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -385539,7 +385529,7 @@ https://doi.org/10.1515/9783110264043 - + An unilaminar epithelium that surrounds a pelvic appendage bud. UBERON:0005232 EHDAA2:0001034 @@ -385555,24 +385545,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0003371 pelvic appendage bud ectoderm - + - + - + EHDAA2 - + EHDAA2 @@ -385640,7 +385630,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -385653,7 +385643,7 @@ https://doi.org/10.1515/9783110264043 - + An unilaminar epithelium that surrounds a pectoral appendage bud. UBERON:0005231 UBERON:0005663 @@ -385670,24 +385660,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0003372 pectoral appendage bud ectoderm - + - + - + EHDAA2 - + EHDAA2 @@ -385751,7 +385741,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -385762,7 +385752,7 @@ https://doi.org/10.1515/9783110264043 - + An extraembryonic structure that develops_from a ectoderm and is part of a chorion. BTO:0005145 EMAPA:16113 @@ -385773,14 +385763,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003374 chorionic ectoderm - + - + ISBN:0073040584 @@ -387229,7 +387219,7 @@ https://doi.org/10.1515/9783110264043 - + A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP]. TODO - check @@ -387244,14 +387234,14 @@ https://doi.org/10.1515/9783110264043 mesenchyme of umbilical cord - + - + Wikipedia @@ -388260,13 +388250,13 @@ https://doi.org/10.1515/9783110264043 - + - + A bone that is part of a facial skeleton [Automatically generated definition]. test whether 'facial bone' is an exact synonym EMAPA:19019 @@ -388287,14 +388277,14 @@ https://doi.org/10.1515/9783110264043 facial bone - + - + MA @@ -388447,14 +388437,14 @@ https://doi.org/10.1515/9783110264043 - + - + The ureteral branches of renal artery are small branches which supply the ureter. ureteric artery @@ -388468,24 +388458,24 @@ https://doi.org/10.1515/9783110264043 ureteric segment of renal artery - + - + - + FMA - + FMA @@ -388569,7 +388559,7 @@ https://doi.org/10.1515/9783110264043 - + The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose. EMAPA:37430 @@ -388586,14 +388576,14 @@ https://doi.org/10.1515/9783110264043 artery of upper lip - + - + FMA @@ -388659,7 +388649,7 @@ https://doi.org/10.1515/9783110264043 - + The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery. EMAPA:37429 @@ -388677,14 +388667,14 @@ https://doi.org/10.1515/9783110264043 artery of lower lip - + - + FMA @@ -389310,7 +389300,7 @@ https://doi.org/10.1515/9783110264043 - + An endothelium of capillary that is part of a respiratory system [Automatically generated definition]. EMAPA:37575 MA:0001808 @@ -389341,14 +389331,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003489 respiratory system capillary endothelium - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -389580,7 +389570,7 @@ https://doi.org/10.1515/9783110264043 - + An arteriole that is part of a respiratory system [Automatically generated definition]. EMAPA:37568 MA:0001803 @@ -389588,14 +389578,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003495 respiratory system arteriole - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -389629,7 +389619,7 @@ https://doi.org/10.1515/9783110264043 - + A blood vessel that is part of a head [Automatically generated definition]. EMAPA:36610 MA:0000575 @@ -389641,14 +389631,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003496 head blood vessel - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -393869,12 +393859,12 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -393901,7 +393891,7 @@ https://doi.org/10.1515/9783110264043 intrahepatic bile duct - + @@ -393914,7 +393904,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -394477,7 +394467,7 @@ https://doi.org/10.1515/9783110264043 - + The central part of the thoracic cavity enclosed by the left and right pleurae. mediastinal CALOHA:TS-2338 @@ -394499,14 +394489,14 @@ https://doi.org/10.1515/9783110264043 mediastinum http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png - + - + FMA @@ -395026,7 +395016,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a thorax [Automatically generated definition]. MA:0000561 muscle organ of thorax @@ -395036,14 +395026,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003830 thoracic segment muscle - + - + prolog @@ -395155,7 +395145,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a esophagus [Automatically generated definition]. merge muscle and muscle layer? EMAPA:26983 @@ -395172,14 +395162,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003832 esophagus muscle - + - + MA @@ -396044,12 +396034,12 @@ https://doi.org/10.1515/9783110264043 - + - + A neural plate that develops_from a future spinal cord. Neural plate that is part of the spinal cord. [Bgee_curator][VHOG] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...)[well established][VHOG] @@ -396062,14 +396052,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003854 spinal cord neural plate - + - + ZFA @@ -396322,7 +396312,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -396338,14 +396328,14 @@ https://doi.org/10.1515/9783110264043 intraembryonic coelom - + - + Wikipedia @@ -396413,7 +396403,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -396472,14 +396462,14 @@ https://doi.org/10.1515/9783110264043 fallopian tube http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg - + - + FMA-abduced-lr @@ -396554,7 +396544,7 @@ https://doi.org/10.1515/9783110264043 - + Paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]. Either of the paired embryonic ducts developing into the uterine tubes, uterus, and vagina in the female and becoming largely obliterated in the male. [TFD][VHOG] Transient developmental organ which gives rise to oviducts in female (documented to persist in some male frogs).[AAO] @@ -396584,14 +396574,14 @@ https://doi.org/10.1515/9783110264043 Mullerian duct http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + - + Wikipedia @@ -396713,8 +396703,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -396748,11 +396738,11 @@ https://doi.org/10.1515/9783110264043 liver primordium - + - + @@ -396771,13 +396761,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + ventral foregut endoderm Zaret 1996 @@ -396900,7 +396890,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -396920,14 +396910,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003898 skeletal muscle tissue of trunk - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -396988,7 +396978,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -397011,7 +397001,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the retina that contains neurons and photoreceptor cells[GO]. (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG] @@ -397043,14 +397033,14 @@ https://doi.org/10.1515/9783110264043 retinal neural layer - + - + Bgee:AN @@ -397370,7 +397360,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -397400,14 +397390,14 @@ https://doi.org/10.1515/9783110264043 pancreas primordium http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png - + - + Wikipedia @@ -397449,16 +397439,16 @@ https://doi.org/10.1515/9783110264043 - - + + - - + + The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]. EFO:0003470 EMAPA:35645 @@ -397479,19 +397469,19 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/4/49/Suckale08FBS_fig1_pancreas_development.jpeg http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png - + - + - + - + @@ -397504,26 +397494,26 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + Wikipedia:Pancreas#Embryological_development - + zebrafish Wikipedia:Pancreatic_bud - + EHDAA2-inferred @@ -397565,8 +397555,8 @@ https://doi.org/10.1515/9783110264043 - - + + Pancreatic bud that gives rise to the accessory pancreatic duct. The pancreatic bud that gives rise to the accessory pancreatic duct.[AAO] In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG] @@ -397594,24 +397584,24 @@ https://doi.org/10.1515/9783110264043 dorsal pancreatic bud http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png - + - + - + EHDAA2 - + XAO @@ -397658,8 +397648,8 @@ https://doi.org/10.1515/9783110264043 - - + + Pancreatic bud that gives rise to the major pancreatic duct. In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG] The ventral pancreatic bud becomes the head and uncinate process, and comes from the hepatic diverticulum[WP] @@ -397687,24 +397677,24 @@ https://doi.org/10.1515/9783110264043 ventral pancreatic bud http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png - + - + - + EHDAA2 - + PMID:16417468 WP @@ -398438,7 +398428,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -398475,14 +398465,14 @@ https://doi.org/10.1515/9783110264043 rete testis http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg - + - + Wikipedia @@ -398901,7 +398891,7 @@ https://doi.org/10.1515/9783110264043 - + A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. Not to be confused with 'dermatome segment of skin'. AAO:0011028 @@ -398928,7 +398918,7 @@ https://doi.org/10.1515/9783110264043 dermatome http://upload.wikimedia.org/wikipedia/commons/f/f3/Gray64.png - + @@ -398941,7 +398931,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2-abduced @@ -399260,7 +399250,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399287,14 +399277,14 @@ https://doi.org/10.1515/9783110264043 biliary ductule - + - + BTO @@ -399385,7 +399375,7 @@ https://doi.org/10.1515/9783110264043 - + The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. consider merging with 'ventricular zone'; note that the MA class probably does not belong here, as this is an embryonic structure The layer of undifferentiated, proliferating cells that line the neural tube lumen @@ -399403,7 +399393,7 @@ https://doi.org/10.1515/9783110264043 neural tube ventricular layer - + @@ -399416,7 +399406,7 @@ https://doi.org/10.1515/9783110264043 - + NCBIBook:NBK10047 @@ -399477,7 +399467,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399501,7 +399491,7 @@ https://doi.org/10.1515/9783110264043 neural tube mantle layer - + @@ -399514,7 +399504,7 @@ https://doi.org/10.1515/9783110264043 - + by division NCBIBook:NBK10047 @@ -399552,7 +399542,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399569,14 +399559,14 @@ https://doi.org/10.1515/9783110264043 neural tube marginal layer - + - + forms from axons @@ -399618,7 +399608,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399643,14 +399633,14 @@ https://doi.org/10.1515/9783110264043 neural tube basal plate - + - + Shh Swenson @@ -399765,7 +399755,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399778,7 +399768,7 @@ https://doi.org/10.1515/9783110264043 - + The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it. Fusion of right and left medial nasal processes forms a primary palate rostrally and the nasal septum caudally. The incisive bone, including upper incisor teeth and the rostral up- per lip, are derived from the primary palate. The nasal septum consists of bone, cartilage, and a patch of soft tissue membrane that separates right & left halves of the nasal cavity. EHDAA2:0001076 @@ -399799,24 +399789,24 @@ https://doi.org/10.1515/9783110264043 medial nasal prominence http://upload.wikimedia.org/wikipedia/commons/8/85/Gray45.png - + - + - + EHDAA2 - + Wikipedia @@ -400657,7 +400647,7 @@ https://doi.org/10.1515/9783110264043 - + A myocardium trabecular layer that is part of a cardiac ventricle. TODO - check FMA FMA:83511 @@ -400671,14 +400661,14 @@ https://doi.org/10.1515/9783110264043 trabecular layer of ventricle - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -400713,9 +400703,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -400748,34 +400738,34 @@ https://doi.org/10.1515/9783110264043 optic vesicle http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png - + - + - + - + ZFA - + GO-def - + ZFA @@ -400924,8 +400914,8 @@ https://doi.org/10.1515/9783110264043 - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] XAO:0004185 @@ -400938,24 +400928,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0004140 primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -401020,7 +401010,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelial tube that will give rise to the mature heart. the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube. AAO:0010411 @@ -401040,14 +401030,14 @@ https://doi.org/10.1515/9783110264043 heart tube - + - + ZFA-modified @@ -401192,8 +401182,8 @@ https://doi.org/10.1515/9783110264043 - - + + The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. the intraventricular conduction system from the bundle of His to the distal Purkinje fibers, which carries the impulse to the ventricles. HPS @@ -401204,11 +401194,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0004146 His-Purkinje system - + - + @@ -401221,13 +401211,13 @@ https://doi.org/10.1515/9783110264043 - + GO - + PMID:12626327 PMID:21234997 github:michaelerice @@ -401408,8 +401398,8 @@ https://doi.org/10.1515/9783110264043 - - + + An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium. propepicardial Proepicardial clusters in Zebrafish form on the pericardial wall, adjacent to the atrioventricular (AV) junction and near the venous pole[ZFA] @@ -401421,24 +401411,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0004160 proepicardium - + - + - + todo check other taxa - + ZFA @@ -402320,8 +402310,8 @@ https://doi.org/10.1515/9783110264043 - - + + A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]. MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa EMAPA:35469 @@ -402337,24 +402327,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0004220 large intestine smooth muscle - + - + - + MA - + consider merging @@ -402435,7 +402425,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -402472,14 +402462,14 @@ https://doi.org/10.1515/9783110264043 intestine smooth muscle - + - + consider merging @@ -403863,7 +403853,7 @@ https://doi.org/10.1515/9783110264043 - + A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]. MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa EMAPA:35783 @@ -403888,14 +403878,14 @@ https://doi.org/10.1515/9783110264043 small intestine smooth muscle - + - + consider merging @@ -404756,13 +404746,13 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -404778,14 +404768,14 @@ https://doi.org/10.1515/9783110264043 eye muscle - + - + MA @@ -404874,7 +404864,7 @@ https://doi.org/10.1515/9783110264043 - + The bilaminar epithelium formed from the myotome and dermatome. Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis. Within the dermomyotome there is also a medio-lateral difference. The central region makes dermis, the mesenchymal connective tissue of the back skin. The medial region (closest to neural tube) makes epaxial muscle, and the lateral region (furthest from neural tube) makes hypaxial muscle[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768]. Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis.[TAO] @@ -404897,7 +404887,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0004290 dermomyotome - + @@ -404916,7 +404906,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 ZFA @@ -405198,11 +405188,11 @@ https://doi.org/10.1515/9783110264043 - - - - - + + + + + A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]. A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals. [TFD][VHOG] Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG] @@ -405227,55 +405217,55 @@ https://doi.org/10.1515/9783110264043 allantois http://upload.wikimedia.org/wikipedia/commons/a/a5/Gray25.png - + - + - + - + - + - + EHDAA2-modified - + Hymans - + Hymans - + hindgut diverticulum endoderm ISBN:0073040584 - + ISBN:0073040584 @@ -405422,14 +405412,14 @@ https://doi.org/10.1515/9783110264043 - + - + Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition. distinction between trophectoderm and trophoblast unclear/inconsistent in many sources The outer cellular layer of the mammalian blastocyst. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.750, see_Kardong_KV][VHOG] @@ -405447,11 +405437,11 @@ https://doi.org/10.1515/9783110264043 trophectoderm - + - + @@ -405464,13 +405454,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -405873,7 +405863,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -405929,14 +405919,14 @@ https://doi.org/10.1515/9783110264043 pharyngeal arch artery http://upload.wikimedia.org/wikipedia/commons/8/84/Gray473.png - + - + ZFA @@ -406188,7 +406178,7 @@ https://doi.org/10.1515/9783110264043 - + A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. Acellular anatomical structure composed of collagen, Descemet's membrane is secreted as a basement membrane of the corneal endothelium. Located between the stroma and the corneal endothelium, it is approximately 0.15 micrometer thick at 6 months post-fertilization.[ZFIN] @@ -406220,14 +406210,14 @@ https://doi.org/10.1515/9783110264043 Descemet's membrane https://github.com/obophenotype/uberon/issues/15 - + - + Cline et al @@ -407645,12 +407635,12 @@ https://doi.org/10.1515/9783110264043 - + - + A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]. Note placement of MA class based on parthood relationship EMAPA:32688 @@ -407661,14 +407651,14 @@ https://doi.org/10.1515/9783110264043 cardiac muscle tissue of myocardium - + - + MA @@ -407855,21 +407845,21 @@ https://doi.org/10.1515/9783110264043 - + A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. FMA:84429 uberon UBERON:0004525 cardiac muscle tissue of trabecula carnea of right ventricle - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -407898,21 +407888,21 @@ https://doi.org/10.1515/9783110264043 - + A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. FMA:84430 uberon UBERON:0004526 cardiac muscle tissue of trabecula carnea of left ventricle - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -408898,7 +408888,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -408932,7 +408922,7 @@ https://doi.org/10.1515/9783110264043 liver lobule - + @@ -408945,7 +408935,7 @@ https://doi.org/10.1515/9783110264043 - + FMA MA @@ -409211,7 +409201,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -409243,14 +409233,14 @@ https://doi.org/10.1515/9783110264043 interventricular septum membranous part - + - + Wikipedia @@ -409457,8 +409447,8 @@ https://doi.org/10.1515/9783110264043 - - + + The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane. BAMS:RA EMAPA:35721 @@ -409487,25 +409477,25 @@ https://doi.org/10.1515/9783110264043 raphe nuclei http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png - + - + - + GO Wikipedia - + Wikipedia @@ -410062,7 +410052,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410074,7 +410064,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410105,7 +410095,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410128,11 +410118,11 @@ https://doi.org/10.1515/9783110264043 paired limb/fin - + - + @@ -410145,13 +410135,13 @@ https://doi.org/10.1515/9783110264043 - + VSAO - + definitional @@ -410233,7 +410223,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410255,14 +410245,14 @@ https://doi.org/10.1515/9783110264043 pelvic appendage - + - + definitional @@ -410331,7 +410321,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410355,14 +410345,14 @@ https://doi.org/10.1515/9783110264043 pectoral appendage - + - + definitional @@ -410904,8 +410894,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -410920,25 +410910,25 @@ https://doi.org/10.1515/9783110264043 UBERON:0004737 metanephric collecting duct - + - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships - + Wikipedia-abduced @@ -410966,7 +410956,7 @@ https://doi.org/10.1515/9783110264043 - + A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] EMAPA:37744 @@ -410980,7 +410970,7 @@ https://doi.org/10.1515/9783110264043 Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from skeletal tissue - + @@ -410993,7 +410983,7 @@ https://doi.org/10.1515/9783110264043 - + 2012-08-14 VSAO:0000015 VSAO @@ -411165,7 +411155,7 @@ https://doi.org/10.1515/9783110264043 - + The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]. in contrast to chondrocranium, this structure is entirely cartiliginous. In Chondricthyes this is the same as the neurocranium. FMA:76621 is an undefined fetal structure, so we assume the correct placement is here. Note that this is distinct from MA:0000317 which is the uberon:neurocranium (the part of the cranium that encloses the brain) AAO:0000094 @@ -411187,7 +411177,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0004761 cartilaginous neurocranium - + @@ -411200,7 +411190,7 @@ https://doi.org/10.1515/9783110264043 - + PMC1571569 @@ -411297,7 +411287,7 @@ https://doi.org/10.1515/9783110264043 - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -411313,14 +411303,14 @@ https://doi.org/10.1515/9783110264043 skeletal element - + - + VSAO @@ -411449,7 +411439,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -411488,14 +411478,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004770 articular system - + - + FMA @@ -411610,7 +411600,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a respiratory system [Automatically generated definition]. EMAPA:37576 MA:0001821 @@ -411625,14 +411615,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004779 respiratory system lamina propria - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -411708,7 +411698,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a gastrointestinal system. MA:0001899 NCIT:C49299 @@ -411717,14 +411707,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004780 gastrointestinal system lamina propria - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -411759,7 +411749,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a gallbladder [Automatically generated definition]. EMAPA:35371 FMA:278594 @@ -411778,14 +411768,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004781 gallbladder lamina propria - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -412380,10 +412370,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + A mucosa that is part of a gastrointestinal system. BTO:0000546 BTO:0005568 @@ -412399,44 +412389,44 @@ https://doi.org/10.1515/9783110264043 The gut mucosa of amphioxus has insulin-secreting cells. http://www.ncbi.nlm.nih.gov/pubmed/16417468 gastrointestinal system mucosa - + - + - + - + - + PMID:16417468 - + PMID:16417468 - + PMID:16417468 - + BTO-modified @@ -414762,7 +414752,7 @@ https://doi.org/10.1515/9783110264043 - + An endothelium of artery that is part of a respiratory system [Automatically generated definition]. EMAPA:37566 @@ -414783,14 +414773,14 @@ https://doi.org/10.1515/9783110264043 respiratory system arterial endothelium - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -415724,7 +415714,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -415747,14 +415737,14 @@ https://doi.org/10.1515/9783110264043 splanchnopleure http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png - + - + EHDAA2 @@ -415782,7 +415772,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -415805,14 +415795,14 @@ https://doi.org/10.1515/9783110264043 somatopleure http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png - + - + EHDAA2 @@ -415878,9 +415868,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -415901,34 +415891,34 @@ https://doi.org/10.1515/9783110264043 urogenital fold - + - + - + - + EHDAA2 - + Wikipedia - + EHDAA2 @@ -416118,7 +416108,7 @@ https://doi.org/10.1515/9783110264043 - + The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra. we follow EHDAA2 in dividing the UGS into epithelium and lumen EHDAA2:0004061 @@ -416129,14 +416119,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004902 urogenital sinus epithelium - + - + EHDAA2 @@ -416612,8 +416602,8 @@ https://doi.org/10.1515/9783110264043 - - + + EHDAA2:0000171 EMAPA:16561 EMAPA_RETIRED:16565 @@ -416624,11 +416614,11 @@ https://doi.org/10.1515/9783110264043 biliary bud http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png - + - + @@ -416641,13 +416631,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2-modified @@ -417818,7 +417808,7 @@ https://doi.org/10.1515/9783110264043 - + The submucous layer of the wall of the urinary bladder. BTO:0002117 @@ -417837,14 +417827,14 @@ https://doi.org/10.1515/9783110264043 submucosa of urinary bladder - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -417918,7 +417908,7 @@ https://doi.org/10.1515/9783110264043 - + A mucosa that is part of a ureter [Automatically generated definition]. FMA:15894 SCTID:40476001 @@ -417939,14 +417929,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004980 mucosa of ureter - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -419060,7 +419050,7 @@ https://doi.org/10.1515/9783110264043 - + A mucosa that is part of a pyloric antrum [Automatically generated definition]. BTO:0004107 FMA:17055 @@ -419093,14 +419083,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004997 mucosa of pyloric antrum - + - + BTO @@ -422043,20 +422033,20 @@ https://doi.org/10.1515/9783110264043 - + Missing definition for term UBERON:0005064. Please replace it using linked reference. uberon UBERON:0005064 left ventricular trabecular myocardium - + - + GO @@ -422083,20 +422073,20 @@ https://doi.org/10.1515/9783110264043 - + Missing definition for term UBERON:0005066. Please replace it using linked reference. uberon UBERON:0005066 right ventricular trabecular myocardium - + - + GO @@ -422456,7 +422446,7 @@ https://doi.org/10.1515/9783110264043 - + Missing definition for term UBERON:0005095. Please replace it using linked reference. class added for consistency with GO - consider merging with kidney mesenchyme. uberon @@ -422464,14 +422454,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005095 kidney rudiment - + - + GO @@ -422662,14 +422652,14 @@ https://doi.org/10.1515/9783110264043 - + - + A metanephric nephron is the functional unit of the metanephros[GO]. The primitive form of the vertebrate nephron consists of a vascular filtration surface overlain with podocytes, a specialized coelomic cavity to receive the ultrafiltrate, and a tubule for modification to final urine. Although previously thought to be unique to the vertebrates, this design is now known to be widespread among invertebrates, including most of the protochordates, and especially their larvae.[well established][VHOG] UBERON:0005142 @@ -422678,25 +422668,25 @@ https://doi.org/10.1515/9783110264043 UBERON:0005110 metanephric nephron - + - + - + Wikipedia Wikipedia:Nephron - + Bgee:AN @@ -422723,20 +422713,20 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0001140 uberon UBERON:0005113 metanephric cortex mesenchyme - + - + EHDAA2 @@ -422758,32 +422748,32 @@ https://doi.org/10.1515/9783110264043 - - + + The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]. uberon UBERON:0005115 metanephric cortical collecting duct - + - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -422812,20 +422802,20 @@ https://doi.org/10.1515/9783110264043 - + The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]. uberon UBERON:0005134 metanephric nephron epithelium - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -422892,7 +422882,7 @@ https://doi.org/10.1515/9783110264043 - + A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]. UBERON:0005128 UBERON:0005152 @@ -422900,14 +422890,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005146 metanephric nephron tubule - + - + ISBN:9780878932504 @@ -422935,7 +422925,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -422951,14 +422941,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005147 metanephric renal vesicle - + - + EHDAA2 @@ -423698,7 +423688,7 @@ https://doi.org/10.1515/9783110264043 - + An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]. EMAPA:37513 @@ -423715,14 +423705,14 @@ https://doi.org/10.1515/9783110264043 deferent duct artery - + - + Wikipedia @@ -424498,7 +424488,7 @@ https://doi.org/10.1515/9783110264043 - + Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head. (Source: BioGlossary, www.Biology-Text.com)[TAO] EFO:0003492 @@ -424520,14 +424510,14 @@ https://doi.org/10.1515/9783110264043 head mesenchyme - + - + EHDAA2 @@ -424594,7 +424584,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -424610,14 +424600,14 @@ https://doi.org/10.1515/9783110264043 trunk mesenchyme - + - + EHDAA2 @@ -424657,7 +424647,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -424681,14 +424671,14 @@ https://doi.org/10.1515/9783110264043 renal cortex artery - + - + MA @@ -424740,7 +424730,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -424763,14 +424753,14 @@ https://doi.org/10.1515/9783110264043 renal cortex vein - + - + MA @@ -424801,14 +424791,14 @@ https://doi.org/10.1515/9783110264043 - + + - @@ -424834,24 +424824,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0005270 renal cortex interstitium - + - + - + MA - + MA @@ -424891,7 +424881,7 @@ https://doi.org/10.1515/9783110264043 - + The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. The posterior of the two brain vesicles formed by specialization of the rhombencephalon in the developing embryo, it comprises the medulla oblongata. [TFD][VHOG] @@ -424916,14 +424906,14 @@ https://doi.org/10.1515/9783110264043 myelencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -425291,7 +425281,7 @@ https://doi.org/10.1515/9783110264043 - + The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals[WP]. TODO - check primary vs testis EHDAA2:0002011 @@ -425308,14 +425298,14 @@ https://doi.org/10.1515/9783110264043 testis sex cord - + - + Bgee:AN @@ -425433,13 +425423,13 @@ https://doi.org/10.1515/9783110264043 - + - + The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]. Bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts. In zebrafish and other teleosts, the pronephric nephron and tubules form after the pronephric duct, connecting to the anterior-most tip of the pronephric ducts. Drummond, 2000.[TAO] @@ -425452,14 +425442,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005310 pronephric nephron tubule - + - + GO @@ -425607,7 +425597,7 @@ https://doi.org/10.1515/9783110264043 - + The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]. AAO:0010390 XAO:0000151 @@ -425615,14 +425605,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005319 mesonephric collecting duct - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -425692,7 +425682,7 @@ https://doi.org/10.1515/9783110264043 - + A nephron that is part of a mesonephros. The structure that is the basic functional unit of the kidney.[AAO] AAO:0010387 @@ -425704,14 +425694,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005322 mesonephric nephron - + - + XAO @@ -425795,20 +425785,20 @@ https://doi.org/10.1515/9783110264043 - + The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]. uberon UBERON:0005330 mesonephric nephron epithelium - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -425837,7 +425827,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -425852,14 +425842,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005331 mesonephric renal vesicle - + - + ZFA @@ -426730,7 +426720,7 @@ https://doi.org/10.1515/9783110264043 - + An apical ectodermal ridge that is part of a pectoral appendage bud. An ectodermal thickening at the end of the forelimb bud in the developing embryo. [TFD][VHOG] Apical ectodermal ridge that is part of the pectoral fin bud.[TAO] @@ -426757,14 +426747,14 @@ https://doi.org/10.1515/9783110264043 pectoral appendage apical ectodermal ridge - + - + EHDAA2 @@ -426881,7 +426871,7 @@ https://doi.org/10.1515/9783110264043 - + An apical ectodermal ridge that is part of a pelvic appendage bud. An ectodermal thickening at the end of the hindlimb bud in the developing embryo. [TFD][VHOG] Apical ectodermal ridge that is part of the pelvic fin bud.[TAO] @@ -426904,14 +426894,14 @@ https://doi.org/10.1515/9783110264043 pelvic appendage apical ectodermal ridge - + - + EHDAA2 @@ -427237,7 +427227,7 @@ https://doi.org/10.1515/9783110264043 - + Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. TAO:0002188 ZFA:0001688 @@ -427245,7 +427235,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005427 corneal primordium - + @@ -427264,7 +427254,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -427364,7 +427354,7 @@ https://doi.org/10.1515/9783110264043 - + The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates. the merged ventral aortae of the embryo which supplies blood to the aortic arches[TMD][http://medical-dictionary.thefreedictionary.com/aortic+sac]. EHDAA2:0004145 @@ -427379,7 +427369,7 @@ https://doi.org/10.1515/9783110264043 aortic sac - + @@ -427392,7 +427382,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -427726,7 +427716,7 @@ https://doi.org/10.1515/9783110264043 - + A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]. sulcus limitans BAMS:slim @@ -427737,14 +427727,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005478 sulcus limitans of neural tube - + - + EHDAA2 @@ -428018,7 +428008,7 @@ https://doi.org/10.1515/9783110264043 - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. BTO:0006179 EHDAA2:0001512 @@ -428037,14 +428027,14 @@ https://doi.org/10.1515/9783110264043 primitive heart tube - + - + ZFA @@ -428126,7 +428116,7 @@ https://doi.org/10.1515/9783110264043 - + Cranial neural crest which gives rise to the trigeminal ganglion. todo - compare ZFA and EHDAA2 representation We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG] @@ -428143,7 +428133,7 @@ https://doi.org/10.1515/9783110264043 trigeminal neural crest - + @@ -428162,7 +428152,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -428188,7 +428178,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -428217,7 +428207,7 @@ https://doi.org/10.1515/9783110264043 gonad primordium - + @@ -428230,7 +428220,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -428288,15 +428278,15 @@ https://doi.org/10.1515/9783110264043 - + - - + + Somite located in the head region, caudal to the otic vesicle. in humans this includes somites 1-4 They provide the epaxial and hypaxial muscles of the neck, the pharyngeal and laryngeal muscles that develop in the caudal branchial arches and the musculature of the tongue. Despite their localisation in the head, myogenic precursors from occipital somites essentially follow the trunk programmes (E. H. Walters and S. D., unpublished). during evolution, have been secondarily incorporated into the head (Gans and Northcutt, 1983) @@ -428310,24 +428300,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0005594 head somite - + - + - + EHDAA2 - + EHDAA2 @@ -428374,7 +428364,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -428394,7 +428384,7 @@ https://doi.org/10.1515/9783110264043 lung primordium - + @@ -428407,7 +428397,7 @@ https://doi.org/10.1515/9783110264043 - + XAO @@ -428480,8 +428470,8 @@ https://doi.org/10.1515/9783110264043 - - + + The portion of mesentery attached to the greater curvature of the stomach is named the dorsal mesentery (or dorsal mesogastrium, when referring to the portion at the stomach), and the part which suspends the colon is termed the mesocolon. The dorsal mesogastrium develops into the greater omentum. The dorsal sheet of the primitive mesentery that encloses the stomach. The greater omentum develops from the dorsal mesogastrium. [TFD][VHOG] EHDAA2:0000416 @@ -428497,11 +428487,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0005602 dorsal mesogastrium - + - + @@ -428514,13 +428504,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -428558,8 +428548,8 @@ https://doi.org/10.1515/9783110264043 - - + + EMAPA:16844 MA:0001636 VHOG:0000215 @@ -428569,24 +428559,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0005604 extrahepatic part of hepatic duct - + - + - + MA - + MA @@ -429275,13 +429265,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0000314 uberon UBERON:0005667 connecting stalk mesoderm - + @@ -429294,7 +429284,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -429802,7 +429792,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -429815,7 +429805,7 @@ https://doi.org/10.1515/9783110264043 - + A mesoderm that has the potential to develop into a pronephros. Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.[AAO] AAO:0011090 @@ -429834,24 +429824,24 @@ https://doi.org/10.1515/9783110264043 the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney pronephric mesoderm - + - + - + ZFA - + Bgee:AN @@ -429938,7 +429928,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0000474 EMAPA:31862 EMAPA:31863 @@ -429950,7 +429940,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005728 extraembryonic mesoderm - + @@ -429963,7 +429953,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -430101,7 +430091,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -430117,14 +430107,14 @@ https://doi.org/10.1515/9783110264043 paired limb/fin field - + - + ISBN:9780878932504 ZFA-inferred @@ -431060,7 +431050,7 @@ https://doi.org/10.1515/9783110264043 - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -431070,7 +431060,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005856 developing mesenchymal condensation - + @@ -431089,7 +431079,7 @@ https://doi.org/10.1515/9783110264043 - + AEO-modified-relation @@ -431111,7 +431101,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -431132,7 +431122,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005863 cartilaginous condensation - + @@ -431145,7 +431135,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -431196,7 +431186,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -431218,14 +431208,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005865 pre-muscle condensation - + - + AEO @@ -431236,7 +431226,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -431256,7 +431246,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005866 pre-cartilage condensation - + @@ -431269,7 +431259,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -431418,8 +431408,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -431458,24 +431448,24 @@ https://doi.org/10.1515/9783110264043 undifferentiated genital tubercle http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png - + - + - + EHDAA2 - + https://github.com/obophenotype/uberon/issues/1230 @@ -431563,8 +431553,8 @@ https://doi.org/10.1515/9783110264043 - - + + The epithelial lining of the surface of the coelom. EHDAA2:0004049 used to be called 'coelomic epithelium' but is now 'gonadal ridge mesothelium' Wikipedia:Coelomic_epithelium @@ -431575,24 +431565,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0005891 coelomic epithelium - + - + - + XAO - + XAO @@ -432029,7 +432019,7 @@ https://doi.org/10.1515/9783110264043 - + trabecula trabecular cartilage EFO:0003677 @@ -432041,7 +432031,7 @@ https://doi.org/10.1515/9783110264043 neurocranial trabecula - + @@ -432054,7 +432044,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -432156,7 +432146,7 @@ https://doi.org/10.1515/9783110264043 - + Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk. infundibulum EMAPA:37926 @@ -432179,14 +432169,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005953 outflow part of right ventricle - + - + PMID:17276708 @@ -432501,7 +432491,7 @@ https://doi.org/10.1515/9783110264043 - + A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]. EMAPA:16076 amnionic fold @@ -432510,14 +432500,14 @@ https://doi.org/10.1515/9783110264043 amniotic fold - + - + ISBN:0073040584 @@ -432712,7 +432702,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -432732,14 +432722,14 @@ https://doi.org/10.1515/9783110264043 atrium myocardial trabecula - + - + ZFA @@ -432791,7 +432781,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -432815,14 +432805,14 @@ https://doi.org/10.1515/9783110264043 atrioventricular septum - + - + PMID:15797462 Wikipedia @@ -432869,7 +432859,7 @@ https://doi.org/10.1515/9783110264043 - + The paired arteries that carry blood to the yolk sac from the dorsal aorta. EHDAA2:0002208 EMAPA:16207 @@ -432881,14 +432871,14 @@ https://doi.org/10.1515/9783110264043 vitelline artery http://upload.wikimedia.org/wikipedia/commons/5/55/Gray31.png - + - + ventral branch @@ -433160,7 +433150,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433191,14 +433181,14 @@ https://doi.org/10.1515/9783110264043 cervical region of vertebral column - + - + FMA @@ -433276,7 +433266,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433310,14 +433300,14 @@ https://doi.org/10.1515/9783110264043 thoracic region of vertebral column - + - + FMA @@ -433498,7 +433488,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433518,14 +433508,14 @@ https://doi.org/10.1515/9783110264043 subdivision of vertebral column - + - + FMA @@ -433607,7 +433597,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433640,14 +433630,14 @@ https://doi.org/10.1515/9783110264043 aortico-pulmonary spiral septum http://upload.wikimedia.org/wikipedia/commons/b/b9/Gray470.png - + - + PMID:6844926 Wikipedia @@ -433702,7 +433692,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433746,14 +433736,14 @@ https://doi.org/10.1515/9783110264043 buccopharyngeal membrane http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png - + - + EHDAA2 @@ -433800,7 +433790,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433841,14 +433831,14 @@ https://doi.org/10.1515/9783110264043 cloacal membrane http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png - + - + Wikipedia @@ -433930,9 +433920,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -433949,34 +433939,34 @@ https://doi.org/10.1515/9783110264043 ethmoid bone primordium - + - + - + - + FMA - + AAO - + EHDAA2 @@ -433997,7 +433987,7 @@ https://doi.org/10.1515/9783110264043 - + A differentiated genital tubercle that is part of a female reproductive system. EHDAA:8118 EMAPA:18680 @@ -434009,14 +433999,14 @@ https://doi.org/10.1515/9783110264043 female genital tubercle - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -434238,8 +434228,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -434258,24 +434248,24 @@ https://doi.org/10.1515/9783110264043 future central tendon - + - + - + EHDAA2 - + mesenchyme cranial part Wikipedia @@ -434311,7 +434301,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -434335,14 +434325,14 @@ https://doi.org/10.1515/9783110264043 future spinal cord - + - + EHDAA2 @@ -434388,8 +434378,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -434407,24 +434397,24 @@ https://doi.org/10.1515/9783110264043 gallbladder primordium - + - + - + EMAPA - + EHDAA2 @@ -434452,7 +434442,7 @@ https://doi.org/10.1515/9783110264043 - + A differentiated genital tubercle that is part of a male reproductive system. EHDAA:8138 EMAPA:17969 @@ -434465,14 +434455,14 @@ https://doi.org/10.1515/9783110264043 male genital tubercle - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -434560,7 +434550,7 @@ https://doi.org/10.1515/9783110264043 - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -434575,7 +434565,7 @@ https://doi.org/10.1515/9783110264043 notochordal plate - + @@ -434588,7 +434578,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -434625,7 +434615,7 @@ https://doi.org/10.1515/9783110264043 - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -434642,14 +434632,14 @@ https://doi.org/10.1515/9783110264043 The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -434728,7 +434718,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -434761,7 +434751,7 @@ https://doi.org/10.1515/9783110264043 pleuroperitoneal canal - + @@ -434774,7 +434764,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -434806,8 +434796,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -434838,24 +434828,24 @@ https://doi.org/10.1515/9783110264043 The embryonic ventricle or primitive ventricle of the developing heart gives rise to the trabeculated parts of the left and right ventricles. In contrast, the smooth parts of the left and right ventricles originate from the embryological bulbus cordis. The primitive ventricle becomes divided by a septum, the septum inferius or ventricular septum, which grows upward from the lower part of the ventricle, its position being indicated on the surface of the heart by a furrow. Its dorsal part increases more rapidly than its ventral portion, and fuses with the dorsal part of the septum intermedium. For a time an interventricular foramen exists above its ventral portion, but this foramen is ultimately closed by the fusion of the aortic septum with the ventricular septum[WP] future cardiac ventricle - + - + - + ZFA - + EMAPA @@ -434905,8 +434895,8 @@ https://doi.org/10.1515/9783110264043 - - + + A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]. check difference between splenic and spleen in EMAPA; note that in EHDAA2 the class 'spleen' refers to the mesenchyme UBERON:0009750 @@ -434923,11 +434913,11 @@ https://doi.org/10.1515/9783110264043 spleen primordium - + - + @@ -434940,13 +434930,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2-modified - + XAO @@ -435011,7 +435001,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA:924 EMAPA:16663 RETIRED_EHDAA2:0002089 @@ -435023,14 +435013,14 @@ https://doi.org/10.1515/9783110264043 See: https://github.com/obophenotype/mouse-anatomy-ontology/issues/13 and https://github.com/obophenotype/uberon/issues/693 -- consider merging into trigeminal ganglion, as this complicates the model future trigeminal ganglion - + - + EHDAA2 @@ -435371,7 +435361,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -435404,14 +435394,14 @@ https://doi.org/10.1515/9783110264043 os penis - + - + Wikipedia @@ -435465,7 +435455,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -435513,14 +435503,14 @@ https://doi.org/10.1515/9783110264043 os clitoris - + - + Wikipedia @@ -437157,7 +437147,7 @@ https://doi.org/10.1515/9783110264043 - + Erectile tissue at the end of the clitoris, which is continuous with the intermediate part of the vestibulovaginal bulbs[BTO]. The clitoral glans (glans clitoridis) is an external portion of the clitoris[WP]. BTO:0003117 EMAPA:19170 @@ -437176,14 +437166,14 @@ https://doi.org/10.1515/9783110264043 glans clitoris http://upload.wikimedia.org/wikipedia/commons/8/8c/Clitoris_inner_anatomy.gif - + - + cjm @@ -437348,7 +437338,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -437361,7 +437351,7 @@ https://doi.org/10.1515/9783110264043 - + The three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers. In mammals, the diaphragm muscle divides the thoracoabdominal cavity into thorax and abdomen. In most mammals, the diaphragm is a flat sheet with muscle fibers radiating outward from a central tendon, and the diaphragm's apposition to the cranial surface of the liver gives it a dome-shape. Muscle fiber contraction reduces the curvature of the dome, thereby expanding the thoracic cavity and aspirating air into the lungs.[well established][VHOG] EMAPA:17702 @@ -437379,24 +437369,24 @@ https://doi.org/10.1515/9783110264043 central tendon of diaphragm - + - + - + VHOG - + definitional @@ -437935,7 +437925,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -437956,7 +437946,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0006815 areolar connective tissue - + @@ -437969,7 +437959,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -438234,7 +438224,7 @@ https://doi.org/10.1515/9783110264043 - + A muscular coat that is part of a ureter. EMAPA:28811 FMA:15893 @@ -438250,14 +438240,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0006855 muscular coat of ureter - + - + FMA @@ -438548,7 +438538,7 @@ https://doi.org/10.1515/9783110264043 - + A head mesenchyme that develops_from a mesoderm. merged in 'head mesoderm' from XAO/AAO and EFO here. Partially implements https://github.com/obophenotype/uberon/wiki/The-neural-crest NC meeting scheme AAO:0011051 @@ -438576,7 +438566,7 @@ https://doi.org/10.1515/9783110264043 head mesenchyme from mesoderm - + @@ -438589,7 +438579,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 XAO @@ -439299,7 +439289,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -439345,14 +439335,14 @@ https://doi.org/10.1515/9783110264043 efferent duct http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg - + - + FMA @@ -439418,7 +439408,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -439446,14 +439436,14 @@ https://doi.org/10.1515/9783110264043 male genital duct https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb - + - + FMA-abduced-lr @@ -439634,7 +439624,7 @@ https://doi.org/10.1515/9783110264043 - + The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis. CALOHA:TS-1246 @@ -439656,14 +439646,14 @@ https://doi.org/10.1515/9783110264043 ovary stroma - + - + FMA @@ -440260,7 +440250,7 @@ https://doi.org/10.1515/9783110264043 - + Cranial neural crest that migrates into the mandibular arch. TAO:0007064 XAO:0000024 @@ -440269,7 +440259,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007098 mandibular neural crest - + @@ -440282,7 +440272,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -440301,7 +440291,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -440312,7 +440302,7 @@ https://doi.org/10.1515/9783110264043 - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -440327,14 +440317,14 @@ https://doi.org/10.1515/9783110264043 Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -440369,8 +440359,8 @@ https://doi.org/10.1515/9783110264043 - - + + One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta. The mouse and human placentas have labyrinthine and villous types of interdigitation between maternal and fetal tissues, respectively The bulk of the villi consist of connective tissues in which blood vessels are found. Most of the cells in the connective tissue core of the villi are fibroblasts. Macrophages known as Hofbauer cells are also present. @@ -440398,24 +440388,24 @@ https://doi.org/10.1515/9783110264043 chorionic villus http://upload.wikimedia.org/wikipedia/commons/1/1e/Gray29.png - + - + - + BTO - + MP-def @@ -441475,7 +441465,7 @@ https://doi.org/10.1515/9783110264043 - + relationship to Meckel's cartilage to be added Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG] EHDAA2:0000031 @@ -441489,14 +441479,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007237 1st arch mandibular component - + - + EHDAA2 @@ -441534,7 +441524,7 @@ https://doi.org/10.1515/9783110264043 - + relationship to palatoquadrate to be added Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG] EHDAA2:0000038 @@ -441545,14 +441535,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007238 1st arch maxillary component - + - + EHDAA2 @@ -441650,7 +441640,7 @@ https://doi.org/10.1515/9783110264043 - + A tunica adventitia that is part of a artery. EMAPA:36295 EV:0100030 @@ -441662,14 +441652,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007240 tunica adventitia of artery - + - + FMA @@ -442115,7 +442105,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442136,14 +442126,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007272 pectoral appendage skeleton - + - + VSAO @@ -442178,7 +442168,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442196,14 +442186,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007273 pelvic appendage skeleton - + - + VSAO @@ -442236,8 +442226,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -442264,24 +442254,24 @@ https://doi.org/10.1515/9783110264043 presumptive hindbrain - + - + - + XAO-abduced - + cjm @@ -442338,7 +442328,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442352,14 +442342,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007278 presumptive sinus venosus - + - + ZFA @@ -442445,7 +442435,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442464,14 +442454,14 @@ https://doi.org/10.1515/9783110264043 presumptive midbrain hindbrain boundary - + - + ZFA @@ -442510,7 +442500,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442527,14 +442517,14 @@ https://doi.org/10.1515/9783110264043 presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -442633,7 +442623,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442659,7 +442649,7 @@ https://doi.org/10.1515/9783110264043 presumptive paraxial mesoderm - + @@ -442675,7 +442665,7 @@ https://doi.org/10.1515/9783110264043 - + https://github.com/obophenotype/uberon/issues/1277 @@ -443069,7 +443059,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -443115,7 +443105,7 @@ https://doi.org/10.1515/9783110264043 pancreatic duct http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png - + @@ -443128,7 +443118,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -443269,7 +443259,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -443296,14 +443286,14 @@ https://doi.org/10.1515/9783110264043 outer epithelium - + - + Wikipedia:Epidermis_(zoology) @@ -443834,7 +443824,7 @@ https://doi.org/10.1515/9783110264043 - + A collection of connected epithelial tubes with a single portal. AEO:0000117 EHDAA2:0003117 @@ -443843,7 +443833,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007501 arborizing epithelial duct system - + @@ -443856,7 +443846,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -443992,7 +443982,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -444000,7 +443990,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007524 dense mesenchyme tissue - + @@ -444013,7 +444003,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -444258,7 +444248,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -444278,14 +444268,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007616 layer of synovial tissue - + - + BTO @@ -444498,7 +444488,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -444524,7 +444514,7 @@ https://doi.org/10.1515/9783110264043 trigeminal nuclear complex http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png - + @@ -444537,7 +444527,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -444786,7 +444776,7 @@ https://doi.org/10.1515/9783110264043 - + EFO:0003626 EHDAA2:0001457 EHDAA:962 @@ -444805,14 +444795,14 @@ https://doi.org/10.1515/9783110264043 early pharyngeal endoderm http://dev.biologists.org/content/128/22/4573.full - + - + cjm @@ -444950,26 +444940,26 @@ https://doi.org/10.1515/9783110264043 - + - + An endothelium that is part of a umbilical artery. BTO:0000857 uberon UBERON:0007778 umbilical artery endothelium - + - + BTO @@ -445099,7 +445089,7 @@ https://doi.org/10.1515/9783110264043 - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -445118,14 +445108,14 @@ https://doi.org/10.1515/9783110264043 vascular system - + - + MA @@ -445159,7 +445149,7 @@ https://doi.org/10.1515/9783110264043 - + A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord. TODO - this is currently defined as a bridge of mesoderm, but in EHDAA2 is extraembryonic structure split into mesoderm and blood vessels BTO:0004705 @@ -445169,7 +445159,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007806 connecting stalk - + @@ -445182,7 +445172,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -445221,7 +445211,7 @@ https://doi.org/10.1515/9783110264043 - + A vasculature that is part of a connecting stalk. EHDAA2:0000313 connecting stalk blood vessels @@ -445231,14 +445221,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007807 connecting stalk vasculature - + - + EHDAA2 @@ -445430,7 +445420,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -445488,14 +445478,14 @@ https://doi.org/10.1515/9783110264043 post-anal tail - + - + possible exception in hemichordates cjm @@ -445660,7 +445650,7 @@ https://doi.org/10.1515/9783110264043 - + Mesentery that is located in the peritoneum. FMA:20570 TAO:0005129 @@ -445670,14 +445660,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007826 peritoneal mesentery - + - + FMA @@ -446044,7 +446034,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -446087,14 +446077,14 @@ https://doi.org/10.1515/9783110264043 pelvic girdle skeleton http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray242.png - + - + PMID:21455939 @@ -446258,8 +446248,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -446285,11 +446275,11 @@ https://doi.org/10.1515/9783110264043 cartilage element - + - + @@ -446302,13 +446292,13 @@ https://doi.org/10.1515/9783110264043 - + VSAO - + VSAO @@ -446517,12 +446507,12 @@ https://doi.org/10.1515/9783110264043 - + - + A bone that is part of a craniocervical region. EMAPA:37245 MA:0000569 @@ -446532,7 +446522,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007914 bone of craniocervical region - + @@ -446545,7 +446535,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -446924,12 +446914,12 @@ https://doi.org/10.1515/9783110264043 - + - + Musculature system of the pharyngeal and head regions. in MA this is restricted to skeletal muscles EMAPA:37259 @@ -446943,7 +446933,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008229 craniocervical region musculature - + @@ -446956,7 +446946,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -447003,8 +446993,8 @@ https://doi.org/10.1515/9783110264043 - - + + Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax. EMAPA:37234 FMA:24217 @@ -447020,25 +447010,25 @@ https://doi.org/10.1515/9783110264043 UBERON:0008231 dorsal thoracic segment of trunk - + - + - + FMA MA - + FMA @@ -447099,13 +447089,13 @@ https://doi.org/10.1515/9783110264043 - + - + A muscle of back that is part of a dorsal thoracic segment of trunk. EMAPA:37261 MA:0000508 @@ -447114,7 +447104,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008243 upper back muscle - + @@ -447127,7 +447117,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -447340,7 +447330,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of a duodenum. CALOHA:TS-2087 @@ -447354,14 +447344,14 @@ https://doi.org/10.1515/9783110264043 duodenal epithelium - + - + FMA @@ -447462,7 +447452,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -447473,7 +447463,7 @@ https://doi.org/10.1515/9783110264043 - + An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers. EHDAA2:0000444 EHDAA:42 @@ -447489,14 +447479,14 @@ https://doi.org/10.1515/9783110264043 The epiblast cells (appearing on day 8 of human embryonic development) make up a columnar epithelium with dense microvilli on the apical surface. During gastrulation, the epiblast cells undergo epithelial-to-mesenchymal transition and delaminate to become the loose mesenchyme of the primitive streak. The epiblast is present in postimplantation mouse embryos between E5.5-E7.5. inner cell mass derived epiblast - + - + Wikipedia @@ -447713,7 +447703,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -447728,7 +447718,7 @@ https://doi.org/10.1515/9783110264043 neural tube derived brain https://github.com/obophenotype/uberon/issues/338 - + @@ -447741,7 +447731,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -447770,7 +447760,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -447790,14 +447780,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0008824 duct of epididymis - + - + FMA @@ -447835,8 +447825,8 @@ https://doi.org/10.1515/9783110264043 - - + + An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts. in mice, the hepatic diverticulum forms by E9 and expands into an obvious liver bud by E10 The caudal part of the septum transversum is invaded by the hepatic diverticulum which divides within it to form the liver and thus gives rise to the ventral mesentery of the foregut. @@ -447855,11 +447845,11 @@ https://doi.org/10.1515/9783110264043 hepatic diverticulum http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png - + - + @@ -447872,14 +447862,14 @@ https://doi.org/10.1515/9783110264043 - + caudal part EHDAA2 - + EHDAA2 @@ -447918,13 +447908,13 @@ https://doi.org/10.1515/9783110264043 - + BTO:0001642 uberon UBERON:0008836 liver bud - + @@ -447937,7 +447927,7 @@ https://doi.org/10.1515/9783110264043 - + http://www.stembook.org/node/512 @@ -447954,7 +447944,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -447966,10 +447956,10 @@ https://doi.org/10.1515/9783110264043 - + + + - - Dense regular connective tissue connecting two or more adjacent skeletal elements[VSAO,modified]. logical definition deliberately made strict to avoid classifying MA:spiral ligament as both nonskeletal and skeletal. see https://github.com/obophenotype/mouse-anatomy-ontology/issues/71 Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ.[VSAO] @@ -447994,44 +447984,44 @@ https://doi.org/10.1515/9783110264043 skeletal ligament https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg - + - + - + - + - + AEO - + AEO - + bones or cartilage organs - + VSAO @@ -448160,7 +448150,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -448187,14 +448177,14 @@ https://doi.org/10.1515/9783110264043 stomach muscularis externa - + - + MA-abduced @@ -448240,7 +448230,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -448272,7 +448262,7 @@ https://doi.org/10.1515/9783110264043 pyloric canal https://upload.wikimedia.org/wikipedia/commons/3/33/Illu_stomach.jpg - + @@ -448285,7 +448275,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -448339,7 +448329,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -448364,7 +448354,7 @@ https://doi.org/10.1515/9783110264043 pyloric gastric gland http://upload.wikimedia.org/wikipedia/commons/b/bf/Gray1054.png - + @@ -448377,7 +448367,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia:Tubular_gland @@ -448437,7 +448427,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -448470,14 +448460,14 @@ https://doi.org/10.1515/9783110264043 hypodermis skeletal muscle layer - + - + MP-def @@ -448659,8 +448649,8 @@ https://doi.org/10.1515/9783110264043 - - + + Subdivision of endoskeleton derived from pharyngeal arches. @@ -448693,24 +448683,24 @@ https://doi.org/10.1515/9783110264043 splanchnocranium http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg - + - + - + https://github.com/obophenotype/uberon/issues/83 - + redundant Grays PMID:11237469 @@ -448828,13 +448818,13 @@ https://doi.org/10.1515/9783110264043 - + - + Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]. Intramembranous bone that forms superficially in the organism.[TAO] other AOs are not yet in sync with this classification @@ -448849,7 +448839,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008907 dermal bone - + @@ -448868,7 +448858,7 @@ https://doi.org/10.1515/9783110264043 - + VSAO @@ -448980,13 +448970,13 @@ https://doi.org/10.1515/9783110264043 - + - + A parenchyma that is part of a lung. EMAPA:35522 FMA:27360 @@ -448999,7 +448989,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008946 lung parenchyma - + @@ -449012,7 +449002,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -449141,12 +449131,12 @@ https://doi.org/10.1515/9783110264043 - + - + The functional tissue of the kidney, consisting of the nephrons. BTO:0003604 FMA:15574 @@ -449157,7 +449147,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008987 renal parenchyma - + @@ -449170,7 +449160,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -449837,13 +449827,13 @@ https://doi.org/10.1515/9783110264043 - + - + Cranial ganglion which develops from an epibranchial placode. BTO:0006250 TAO:0001555 @@ -449854,7 +449844,7 @@ https://doi.org/10.1515/9783110264043 Epibranchial ganglia orchestrate the development of the cranial neurogenic crest epibranchial ganglion - + @@ -449867,7 +449857,7 @@ https://doi.org/10.1515/9783110264043 - + NCBIBook:NBK53175 @@ -449919,8 +449909,8 @@ https://doi.org/10.1515/9783110264043 - - + + Endocardium that is part of the right atrium. EHDAA2:0000274 FMA:7281 @@ -449934,24 +449924,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009129 right atrium endocardium - + - + - + EHDAA2 - + EHDAA2 @@ -450115,7 +450105,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -450132,14 +450122,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -450155,7 +450145,7 @@ https://doi.org/10.1515/9783110264043 - + EMAPA:16549 RETIRED_EHDAA2:0001454 pharyngeal region @@ -450163,14 +450153,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009145 pharyngeal region of foregut - + - + EHDAA2 @@ -450207,8 +450197,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -450222,11 +450212,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0009191 sphenoid bone pre-cartilage condensation - + - + @@ -450245,13 +450235,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -450386,12 +450376,12 @@ https://doi.org/10.1515/9783110264043 - + - + Mesenchyme that is part of a medial nasal prominence. EHDAA2:0001077 EMAPA:16810 @@ -450400,14 +450390,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009204 medial nasal process mesenchyme - + - + EHDAA2 @@ -450642,7 +450632,7 @@ https://doi.org/10.1515/9783110264043 - + A portion of mesenchymal tissue associated with an individual pharyngeal arch. this represents a part of the entire arch mesenchyme (UBERON:0010046), and is therefore a superclass of the individual arch mesenchyme classes. Alternate definition: primordial embryonic connective tissue associated with the branchial arches, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to facial and cranial nerve-associated structures. EMAPA:32755 @@ -450654,7 +450644,7 @@ https://doi.org/10.1515/9783110264043 pharyngeal arch mesenchymal region - + @@ -450667,7 +450657,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -450714,14 +450704,14 @@ https://doi.org/10.1515/9783110264043 - + - + An epithelium that is part of a foregut-midgut junction. EHDAA2:0000573 EMAPA:16564 @@ -450730,24 +450720,24 @@ https://doi.org/10.1515/9783110264043 epithelium of foregut-midgut junction - + - + - + EHDAA2 - + EHDAA2 @@ -451196,7 +451186,7 @@ https://doi.org/10.1515/9783110264043 - + A submucosa that is part of a intestine. FMA:15696 submucosa of intestine @@ -451204,14 +451194,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009566 intestinal submucosa - + - + FMA @@ -451424,7 +451414,7 @@ https://doi.org/10.1515/9783110264043 - + A sulcus limitans of neural tube that is part of a future medulla oblongata. EHDAA2:0001100 EMAPA:17561 @@ -451432,14 +451422,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009576 medulla oblongata sulcus limitans - + - + EHDAA2 @@ -451615,12 +451605,12 @@ https://doi.org/10.1515/9783110264043 - + - + Mesenchyme that is part of a 1st arch mandibular component. UBERON:0010043 EHDAA2:0000034 @@ -451633,14 +451623,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009584 1st arch mandibular mesenchyme - + - + EMAPA @@ -451756,9 +451746,9 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -451772,7 +451762,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0009611 midbrain neural plate - + @@ -451781,20 +451771,20 @@ https://doi.org/10.1515/9783110264043 - + - + ZFA - + ZFA @@ -451809,9 +451799,9 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -451825,7 +451815,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0009614 hindbrain neural plate - + @@ -451834,20 +451824,20 @@ https://doi.org/10.1515/9783110264043 - + - + ZFA - + ZFA @@ -451863,14 +451853,14 @@ https://doi.org/10.1515/9783110264043 - + - + TODO - developmental relationships for lines TAO:0007044 ZFA:0007044 @@ -451880,24 +451870,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009615 midbrain hindbrain boundary neural plate - + - + - + ZFA - + https://github.com/obophenotype/uberon/issues/438 Bgee:AN @@ -451931,14 +451921,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -451963,24 +451953,24 @@ https://doi.org/10.1515/9783110264043 presumptive midbrain - + - + - + ZFA - + ZFA @@ -452026,7 +452016,7 @@ https://doi.org/10.1515/9783110264043 - + Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles. A major contributor to neurocranium [PMID:16313393] EHDAA2:0000736 @@ -452043,14 +452033,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009617 head paraxial mesoderm - + - + EHDAA2 @@ -452103,7 +452093,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -452111,14 +452101,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -452189,7 +452179,7 @@ https://doi.org/10.1515/9783110264043 - + A basement membrane that is part of a nephron tubule. EMAPA:37490 MA:0001680 @@ -452203,14 +452193,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009651 nephron tubule basement membrane - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -452383,7 +452373,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004566 EMAPA:32911 MA:0003203 @@ -452394,14 +452384,14 @@ https://doi.org/10.1515/9783110264043 gut mesentery https://github.com/obophenotype/uberon/issues/509 - + - + EHDAA2 @@ -452488,8 +452478,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -452506,24 +452496,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009670 rectal lumen - + - + - + cjm - + EHDAA2 @@ -452547,9 +452537,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + EHDAA2:0001371 uberon @@ -452559,15 +452549,15 @@ https://doi.org/10.1515/9783110264043 dorsal pancreas - + - + - + @@ -452580,19 +452570,19 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 - + cjm @@ -452604,9 +452594,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + EHDAA2:0001393 uberon @@ -452616,15 +452606,15 @@ https://doi.org/10.1515/9783110264043 ventral pancreas - + - + - + @@ -452637,19 +452627,19 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 - + cjm @@ -452676,8 +452666,8 @@ https://doi.org/10.1515/9783110264043 - - + + Any endocardium that is part of the right ventricle of the heart. Endocardium of ventricle which is continuous tricuspid valve, pulmonary valve and with the tunica intima of the pulmonary trunk. EHDAA2:0002188 @@ -452694,24 +452684,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009712 endocardium of right ventricle - + - + - + EHDAA2 - + FMA @@ -452774,7 +452764,7 @@ https://doi.org/10.1515/9783110264043 - + Any endocardium that is part of the left ventricle of the heart. Endocardium of ventricle which is continuous with mitral valve, aortic valve, atrioventricular septum and the tunica intima of the aorta. EHDAA2:0002182 @@ -452790,14 +452780,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009713 endocardium of left ventricle - + - + FMA @@ -452889,7 +452879,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -452904,14 +452894,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009722 entire pharyngeal arch endoderm - + - + EHDAA2 @@ -453114,7 +453104,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -453127,7 +453117,7 @@ https://doi.org/10.1515/9783110264043 - + A serous sac that has the pleura and the pleural cavity as parts. despite its name the class EHDAA2:0004737 is not a true cavity, it corresponds to what we call the sac EHDAA2:0004737 @@ -453138,24 +453128,24 @@ https://doi.org/10.1515/9783110264043 pleural sac - + - + - + FMA - + FMA-abduced-lr @@ -453268,7 +453258,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -453287,14 +453277,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009844 urogenital sinus lumen - + - + EHDAA2 @@ -453309,7 +453299,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -453325,7 +453315,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0009845 urogenital sinus mesenchyme - + @@ -453337,7 +453327,7 @@ https://doi.org/10.1515/9783110264043 - + PMID:18977204 @@ -453379,8 +453369,8 @@ https://doi.org/10.1515/9783110264043 - - + + An epithelium that is part of a embryonic cloaca. cloacal epithelium EHDAA2:0004585 @@ -453388,24 +453378,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009846 embryonic cloacal epithelium - + - + - + EHDAA2 - + EHDAA2 @@ -453638,7 +453628,7 @@ https://doi.org/10.1515/9783110264043 - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -453648,14 +453638,14 @@ https://doi.org/10.1515/9783110264043 anterior lateral plate mesoderm - + - + ZFA @@ -453671,7 +453661,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -453701,7 +453691,7 @@ https://doi.org/10.1515/9783110264043 medullary ray - + @@ -453714,7 +453704,7 @@ https://doi.org/10.1515/9783110264043 - + MP @@ -453968,9 +453958,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -453990,34 +453980,34 @@ https://doi.org/10.1515/9783110264043 UBERON:0009889 secondary heart field - + - + - + - + GO:0003129 - + PMID:17276708 - + PMID:17276708 @@ -454288,7 +454278,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -454327,14 +454317,14 @@ https://doi.org/10.1515/9783110264043 Alternate definition: One of the subdivisions of the kidney, consisting of a medullary ray and that portion of the convoluted port (renal corpuscles and convoluted tubules) associated with its collecting duct. -http://www.mondofacto.com/facts/dictionary?lobulus+corticalis+renalis renal lobule - + - + FMA @@ -454524,14 +454514,14 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0001315 EHDAA:1122 uberon UBERON:0009920 optic neural crest - + @@ -454544,7 +454534,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -454718,10 +454708,10 @@ https://doi.org/10.1515/9783110264043 - + - - + + @@ -454741,7 +454731,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0009958 bladder lumen - + @@ -454750,30 +454740,30 @@ https://doi.org/10.1515/9783110264043 - + - + - + FMA - + FMA - + EHDAA2 @@ -454883,7 +454873,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -454915,14 +454905,14 @@ https://doi.org/10.1515/9783110264043 ureteropelvic junction - + - + MP @@ -454966,7 +454956,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -454999,14 +454989,14 @@ https://doi.org/10.1515/9783110264043 ureterovesical junction - + - + MP @@ -455318,8 +455308,8 @@ https://doi.org/10.1515/9783110264043 - - + + The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells. EHDAA2:0001459 EMAPA:16550 @@ -455331,11 +455321,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0010046 entire pharyngeal arch associated mesenchyme - + - + @@ -455348,13 +455338,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + cjm @@ -455535,9 +455525,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -455551,34 +455541,34 @@ https://doi.org/10.1515/9783110264043 UBERON:0010083 future dermis - + - + - + - + EHDAA2 - + EHDAA2 - + XAO @@ -455605,9 +455595,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -455620,34 +455610,34 @@ https://doi.org/10.1515/9783110264043 UBERON:0010084 future diaphragm - + - + - + - + EHDAA2 - + PMID:23586979 - + PMID:23586979 @@ -455834,7 +455824,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -455843,7 +455833,7 @@ https://doi.org/10.1515/9783110264043 - + A sex cord that is part of a indifferent gonad. note that this represents the indifferent structure. EHDAA2:0004051 @@ -455853,7 +455843,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010141 primitive sex cord of indifferent gonad - + @@ -455862,20 +455852,20 @@ https://doi.org/10.1515/9783110264043 - + - + EHDAA2 - + EHDAA2 @@ -456086,7 +456076,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456104,14 +456094,14 @@ https://doi.org/10.1515/9783110264043 post-anal tail tip - + - + MA @@ -456387,7 +456377,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456404,7 +456394,7 @@ https://doi.org/10.1515/9783110264043 pair of dorsal aortae - + @@ -456417,7 +456407,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -456440,7 +456430,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456452,14 +456442,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010191 aortic system - + - + Wikipedia @@ -456642,7 +456632,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456660,14 +456650,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010227 future cardiac atrium - + - + ZFA @@ -456702,7 +456692,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456727,14 +456717,14 @@ https://doi.org/10.1515/9783110264043 eyeball of camera-type eye - + - + FMA @@ -456820,7 +456810,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456830,8 +456820,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -456844,11 +456834,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0010252 1st arch mandibular mesenchyme from neural crest - + - + @@ -456861,13 +456851,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -456886,7 +456876,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456896,32 +456886,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme. EHDAA2:0000044 uberon UBERON:0010253 1st arch maxillary mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -456940,7 +456930,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456951,8 +456941,8 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme. In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG] EHDAA2:0000098 @@ -456967,24 +456957,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0010256 4th arch mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -457025,7 +457015,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -457036,8 +457026,8 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme. EHDAA2:0004077 neural crest derived arch 6 mesenchyme @@ -457047,24 +457037,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0010257 6th arch mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -457091,7 +457081,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -457104,14 +457094,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010258 mesenchyme from rhombencephalic neural crest - + - + EHDAA2 @@ -457284,8 +457274,8 @@ https://doi.org/10.1515/9783110264043 - - + + Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. DHBA:12322 EFO:0003567 @@ -457299,11 +457289,11 @@ https://doi.org/10.1515/9783110264043 midbrain basal plate - + - + @@ -457316,13 +457306,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + ZFA @@ -457351,7 +457341,7 @@ https://doi.org/10.1515/9783110264043 - + Portion of neural tube that gives rise to the midbrain. we follow ZFA in temporally dividing midbrain NT from presumptive midbrain, but in future this may be collapsed TAO:0007039 @@ -457360,14 +457350,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010286 midbrain neural tube - + - + ZFA @@ -457384,20 +457374,20 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia:Sclera#Histology uberon UBERON:0010291 layer of sclera - + - + cjm @@ -457667,7 +457657,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -457683,14 +457673,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010312 immature eye - + - + definitional @@ -457942,20 +457932,20 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a limb/fin bud. uberon UBERON:0010329 paired limb/fin bud mesenchyme - + - + EHDAA2-abduced @@ -457990,20 +457980,20 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a extraembryonic membrane. uberon UBERON:0010333 extraembryonic membrane mesenchyme - + - + EHDAA2-abduced @@ -458022,7 +458012,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458032,32 +458022,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme. EHDAA2:0004601 uberon UBERON:0010334 maxillary process mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -458076,7 +458066,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458086,32 +458076,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme. EHDAA2:0004602 uberon UBERON:0010335 maxillary process mesenchyme from head mesenchyme - + - + - + EHDAA2 - + EHDAA2 @@ -458130,7 +458120,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458140,32 +458130,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme. EHDAA2:0004603 uberon UBERON:0010336 mandibular process mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -458184,7 +458174,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458194,32 +458184,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme. EHDAA2:0004604 uberon UBERON:0010337 mandibular process mesenchyme from head mesenchyme - + - + - + EHDAA2 - + EHDAA2 @@ -458238,7 +458228,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458248,21 +458238,21 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme. EHDAA2:0000043 uberon UBERON:0010338 1st arch maxillary mesenchyme from head mesenchyme - + - + EHDAA2 @@ -458281,7 +458271,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458291,21 +458281,21 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme. EHDAA2:0000036 uberon UBERON:0010339 1st arch mandibular mesenchyme from head mesenchyme - + - + EHDAA2 @@ -458324,7 +458314,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458335,7 +458325,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme. EMAPA:16130 mesenchyme derived from head mesoderm of mesenchyme of 1st arch @@ -458343,14 +458333,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010341 1st arch mesenchyme from head mesenchyme - + - + EMAPA @@ -458375,7 +458365,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458386,7 +458376,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme. EHDAA2:0000097 EMAPA:16771 @@ -458398,14 +458388,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010345 4th arch mesenchyme from head mesenchyme - + - + EHDAA2 @@ -458430,7 +458420,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458441,7 +458431,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme. EHDAA2:0004078 head mesenchyme derived arch 6 mesenchyme @@ -458451,14 +458441,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010347 6th arch mesenchyme from head mesenchyme - + - + EHDAA2 @@ -458825,7 +458815,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458840,14 +458830,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010375 pancreas dorsal primordium - + - + EHDAA2 @@ -458876,7 +458866,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458891,14 +458881,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010376 pancreas ventral primordium - + - + EHDAA2 @@ -458932,7 +458922,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458946,7 +458936,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010377 mesenchyme from somatopleure - + @@ -458959,7 +458949,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -458992,7 +458982,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -459005,7 +458995,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010378 mesenchyme from splanchnopleure - + @@ -459018,7 +459008,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -459108,7 +459098,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -459129,14 +459119,14 @@ https://doi.org/10.1515/9783110264043 spleen trabecular artery - + - + MP @@ -459600,7 +459590,7 @@ https://doi.org/10.1515/9783110264043 - + Skeletal element that forms as a replacement or substitution of another element or tissue. VSAO:0000135 XAO:0004016 @@ -459609,7 +459599,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010522 replacement element - + @@ -459622,7 +459612,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -459641,7 +459631,7 @@ https://doi.org/10.1515/9783110264043 - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -459651,14 +459641,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010523 microcirculatory vessel - + - + ZFA @@ -459769,7 +459759,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -459793,14 +459783,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010531 metanephros induced blastemal cells - + - + EHDAA2 @@ -459848,7 +459838,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -459865,7 +459855,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010532 primitive nephron - + @@ -459878,7 +459868,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -459903,13 +459893,13 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -459922,14 +459912,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010533 metanephros cortex - + - + VHOG @@ -459998,7 +459988,7 @@ https://doi.org/10.1515/9783110264043 - + A primitive nephron that is part of a metanephros. primitive nephron EHDAA2:0001516 @@ -460008,14 +459998,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010535 primitive metanephric nephron - + - + EHDAA2 @@ -460037,7 +460027,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -460048,7 +460038,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010536 nephron progenitor - + @@ -460061,7 +460051,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -460550,7 +460540,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -460573,14 +460563,14 @@ https://doi.org/10.1515/9783110264043 bone of appendage girdle complex - + - + UBERONREF:0000003 @@ -460755,7 +460745,7 @@ https://doi.org/10.1515/9783110264043 - + Muscles of the pelvic girdle, hindlimb or pelvic fin. Muscles of the pelvic girdle, thigh, leg (crus), and foot (pes).[AAO] AAO:0000218 @@ -460773,14 +460763,14 @@ https://doi.org/10.1515/9783110264043 pelvic complex muscle - + - + prolog @@ -460848,7 +460838,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle of a pectoral girdle, pectoral fin or anterior limb. the MA class belongs here, based on its current child classes Muscles of the pectoral girdle, arm, forearm, and hand (brachium, antebrachium, manus respectively).[AAO] @@ -460865,14 +460855,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010891 pectoral complex muscle - + - + prolog @@ -460994,8 +460984,8 @@ https://doi.org/10.1515/9783110264043 - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO] FMA:23879 @@ -461008,11 +460998,11 @@ https://doi.org/10.1515/9783110264043 subdivision of skeleton - + - + @@ -461025,13 +461015,13 @@ https://doi.org/10.1515/9783110264043 - + UBERONREF:0000003 - + VSAO @@ -461070,7 +461060,7 @@ https://doi.org/10.1515/9783110264043 - + Skeletal element that forms around the notochord and is part of the vertebral column. we include a distinct subclass for bony vertebra In contrast to lampreys and jawed vertebrates, hagfishes were thought to lack vertebrae. Now, long overlooked vertebral rudiments have been analysed in hagfish, suggesting that vertebrae existed in the last common ancestor of all vertebrates.[well established][VHOG] @@ -461087,7 +461077,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010913 vertebral element - + @@ -461101,7 +461091,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -461165,7 +461155,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of either the head or the neck. NCIT:C32716 UMLS:C0448281 @@ -461175,14 +461165,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010959 craniocervical muscle - + - + prolog @@ -461207,12 +461197,12 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -461231,7 +461221,7 @@ https://doi.org/10.1515/9783110264043 pharyngeal arch cartilage - + @@ -461244,7 +461234,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -461288,7 +461278,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -461316,7 +461306,7 @@ https://doi.org/10.1515/9783110264043 palatoquadrate arch - + @@ -461329,7 +461319,7 @@ https://doi.org/10.1515/9783110264043 - + VHOG @@ -461882,7 +461872,7 @@ https://doi.org/10.1515/9783110264043 - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -461893,7 +461883,7 @@ https://doi.org/10.1515/9783110264043 postcranial axial skeletal system http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton - + @@ -461906,7 +461896,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -461930,7 +461920,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -461943,7 +461933,7 @@ https://doi.org/10.1515/9783110264043 - + Subdivision of urinary system which consists of the kidney and the ureters. FMA:45658 @@ -461956,24 +461946,24 @@ https://doi.org/10.1515/9783110264043 upper urinary tract - + - + - + FMA - + FMA-abduced-lr @@ -462006,7 +461996,7 @@ https://doi.org/10.1515/9783110264043 - + Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue. BTO:0003751 EMAPA:37970 @@ -462015,14 +462005,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011148 submucosal gland - + - + perforates @@ -462046,7 +462036,7 @@ https://doi.org/10.1515/9783110264043 - + Subdivision of skull that consists of the facial bones. EHDAA2:0002206 EHDAA:8361 @@ -462065,7 +462055,7 @@ https://doi.org/10.1515/9783110264043 facial skeleton http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg - + @@ -462078,7 +462068,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -462363,7 +462353,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a large intestine. FMA:15654 @@ -462377,14 +462367,14 @@ https://doi.org/10.1515/9783110264043 lamina propria of large intestine - + - + FMA @@ -462429,7 +462419,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle layer that is part of a large intestine. FMA:14971 NCIT:C32927 @@ -462442,14 +462432,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011198 muscle layer of large intestine - + - + FMA @@ -462507,7 +462497,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle layer that is part of a small intestine. FMA:14932 NCIT:C33569 @@ -462523,14 +462513,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011201 muscle layer of small intestine - + - + FMA @@ -462688,7 +462678,7 @@ https://doi.org/10.1515/9783110264043 - + Muscles within the eye (bulbus oculi).[AAO] AAO:0010038 EMAPA:18808 @@ -462699,14 +462689,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011222 intra-ocular muscle - + - + EMAPA @@ -462907,7 +462897,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the trunk that is in the dorsum[cjm]. In humans, the subdivision of trunk which is demarcated from the trunk proper by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines, the external surface of the posterior abdominal wall; together with the trunk proper, it constitutes the trunk[FMA] EMAPA:35162 @@ -462922,7 +462912,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0011270 dorsal trunk - + @@ -462935,7 +462925,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -462971,8 +462961,8 @@ https://doi.org/10.1515/9783110264043 - - + + compare with 'stratum basale of epidermis'. This class is the source for many adult structures - see WP2062. See also: 'enveloping layer of ectoderm' EHDAA2:0001845 uberon @@ -462981,11 +462971,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0011272 embryonic skin basal layer - + - + @@ -462998,13 +462988,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -463186,7 +463176,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -463210,14 +463200,14 @@ https://doi.org/10.1515/9783110264043 lumen of esophagus - + - + FMA @@ -463331,7 +463321,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -463349,14 +463339,14 @@ https://doi.org/10.1515/9783110264043 paired limb/fin skeleton - + - + ISBN:9780878932504 @@ -463418,19 +463408,19 @@ https://doi.org/10.1515/9783110264043 - - + + EHDAA2:0002120 upper jaw future lip uberon UBERON:0011592 future upper lip - + - + @@ -463443,13 +463433,13 @@ https://doi.org/10.1515/9783110264043 - + fusion - + fusion @@ -463477,7 +463467,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -463498,14 +463488,14 @@ https://doi.org/10.1515/9783110264043 jaw region http://eol.org/collections/11578 - + - + EMAPA FMA-abduced ZFA-abduced @@ -463524,14 +463514,14 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0001020 lower jaw future lip uberon UBERON:0011596 future lower lip - + @@ -463544,7 +463534,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia:Mandibular_prominence @@ -463621,14 +463611,14 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that develops_from a ectoderm and is part of a oral epithelium. EHDAA2:0004137 uberon UBERON:0011642 oral epithelium from ectoderm - + @@ -463641,7 +463631,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -464697,7 +464687,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle layer that is part of a wall of esophagus. In the upper esophagus, part of the externa is skeletal muscle, rather than smooth muscle FMA:62998 @@ -464711,14 +464701,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011878 muscle layer of esophagus - + - + upper part Wikipedia:Muscular_layer @@ -464787,7 +464777,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -464829,7 +464819,7 @@ https://doi.org/10.1515/9783110264043 anterior uvea - + @@ -464842,7 +464832,7 @@ https://doi.org/10.1515/9783110264043 - + MP @@ -464883,7 +464873,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -464908,7 +464898,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0011899 epimysium - + @@ -464921,7 +464911,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -464974,7 +464964,7 @@ https://doi.org/10.1515/9783110264043 - + Masses of developing blood cells attached to endothelium in the yolk sac. EHDAA2:0000177 EMAPA:16115 @@ -464985,14 +464975,14 @@ https://doi.org/10.1515/9783110264043 yolk sac blood island - + - + EHDAA2 @@ -465022,8 +465012,8 @@ https://doi.org/10.1515/9783110264043 - - + + in EHDAA2 gives rise to connecting stalk blood vessels and extraembryonic umbilical vessels EHDAA2:0003242 blood island of umbilical vesicle @@ -465032,11 +465022,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0011921 connecting stalk blood islands - + - + @@ -465049,13 +465039,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -465747,7 +465737,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -465775,7 +465765,7 @@ https://doi.org/10.1515/9783110264043 urinary bladder vasculature - + @@ -465787,7 +465777,7 @@ https://doi.org/10.1515/9783110264043 - + EMAPA @@ -466325,7 +466315,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -466340,14 +466330,14 @@ https://doi.org/10.1515/9783110264043 We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts embryonic cloacal fold - + - + EHDAA2 @@ -466533,7 +466523,7 @@ https://doi.org/10.1515/9783110264043 - + The deep cervical artery (Profunda cervicalis) is an artery of the neck. FMA:10659 @@ -466545,14 +466535,14 @@ https://doi.org/10.1515/9783110264043 deep cervical artery - + - + FMA @@ -466781,20 +466771,20 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004588 uberon UBERON:0012361 internal anal region - + - + EHDAA2 @@ -466815,7 +466805,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle layer that is part of an intestine. FMA:15697 intestinal muscularis propria @@ -466825,14 +466815,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0012367 muscle layer of intestine - + - + FMA @@ -466937,7 +466927,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -466962,14 +466952,14 @@ https://doi.org/10.1515/9783110264043 muscle layer of urinary bladder - + - + FMA @@ -467229,7 +467219,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -467251,7 +467241,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0012429 hematopoietic tissue - + @@ -467264,7 +467254,7 @@ https://doi.org/10.1515/9783110264043 - + defitional @@ -467410,7 +467400,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -467427,14 +467417,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0012463 cloacal lumen - + - + cjm @@ -467630,20 +467620,20 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004589 uberon UBERON:0012469 external anal region - + - + EHDAA2 @@ -467670,7 +467660,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -467690,14 +467680,14 @@ https://doi.org/10.1515/9783110264043 skeleton of pectoral complex - + - + FMA @@ -467766,7 +467756,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -467786,14 +467776,14 @@ https://doi.org/10.1515/9783110264043 skeleton of pelvic complex - + - + FMA @@ -467845,8 +467835,8 @@ https://doi.org/10.1515/9783110264043 - - + + The posterior region of the neck, including the suboccipital region. nuchal nape @@ -467869,11 +467859,11 @@ https://doi.org/10.1515/9783110264043 dorsal part of neck - + - + @@ -467886,13 +467876,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + FMA @@ -468851,7 +468841,7 @@ https://doi.org/10.1515/9783110264043 - + A vein that drains a lip. SCTID:367664002 labial vein of face @@ -468862,14 +468852,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013136 vein of lip - + - + FMA @@ -469212,12 +469202,12 @@ https://doi.org/10.1515/9783110264043 - + - + A future glans that is part of a male genital tubercle. EMAPA:29252 glans of male genital tubercle @@ -469225,14 +469215,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013239 future glans penis - + - + EMAPA @@ -469251,12 +469241,12 @@ https://doi.org/10.1515/9783110264043 - + - + A future glans that is part of a female genital tubercle. EMAPA:19170 glans of female genital tubercle @@ -469264,14 +469254,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013240 future glans clitoris - + - + EMAPA @@ -469287,7 +469277,7 @@ https://doi.org/10.1515/9783110264043 - + The precursor of the urethra. In humans, the urethral groove is a temporary linear indentation on the underside (ventral side) of the male penis during embryonic development. It typically appears around 8 weeks of gestation and becomes closed into a normal male urethra by the 12th week SCTID:361531004 @@ -469299,14 +469289,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013241 embryonic urethral groove - + - + Wikipedia @@ -469338,16 +469328,16 @@ https://doi.org/10.1515/9783110264043 - - + + - - + + An epithelial tube that develops from a Mullerian duct in a male. Later degenerates. consider separating the duct from the degenerating portion, as in EMAPA EHDAA2:0001052 @@ -469358,24 +469348,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0013247 male paramesonephric duct - + - + - + EHDAA2 - + EHDAA2 @@ -469408,7 +469398,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -469432,14 +469422,14 @@ https://doi.org/10.1515/9783110264043 cranial cavity http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg - + - + Wikipedia @@ -470018,7 +470008,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -470035,14 +470025,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013525 stomach lumen - + - + FMA @@ -470093,7 +470083,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of a intestinal villus. FMA:63587 intestinal villus epithelium @@ -470103,14 +470093,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013636 epithelium of intestinal villus - + - + FMA @@ -471970,7 +471960,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of a frontonasal prominence. EHDAA2:0004108 EMAPA:32918 @@ -471978,7 +471968,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0014702 frontonasal process epithelium - + @@ -471991,7 +471981,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -472066,7 +472056,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -472081,14 +472071,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0014704 pleuroperitoneal canal lumen - + - + EHDAA2 @@ -472111,7 +472101,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0001147 EMAPA:17646 metanephros primitive collecting ducts @@ -472120,7 +472110,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0014706 primitive renal collecting duct system - + @@ -472133,7 +472123,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -472635,20 +472625,20 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin). uberon UBERON:0014794 pectoral appendage muscle - + - + prolog @@ -472675,20 +472665,20 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a pelvic appendage (hindlimb or pelvic fin). uberon UBERON:0014795 pelvic appendage muscle - + - + prolog @@ -472925,7 +472915,7 @@ https://doi.org/10.1515/9783110264043 - + One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites. Blood vessels that connect the dorsal aorta or the posterior cardinal vein and the dorsal longitudinal anastomotic vessel. They run along the vertical myotomal boundaries. At early stages these don't have venous or arterial markers[ZFA:0001285, ZFIN:ZDB-PUB-030908-4]. EFO:0003664 @@ -472943,7 +472933,7 @@ https://doi.org/10.1515/9783110264043 intersomitic vessel - + @@ -472956,7 +472946,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -473183,7 +473173,7 @@ https://doi.org/10.1515/9783110264043 - + consider merging into myocardial compact layer FMA:83105 perimysial connective tissue of subepicardium @@ -473192,14 +473182,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0015128 subepicardial layer of epicardium - + - + FMA @@ -473299,7 +473289,7 @@ https://doi.org/10.1515/9783110264043 - + A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands. the only orbital gland found in anuran amphibians is either the Harderian or the lacrimal; if it is a lacrimal, then a progressive lateral migration of the lacrimal glands must occur through the amniotes[PMID:7559104] the only orbital gland found in anuran amphibians is the Harderian[PMID:8843648] @@ -473310,14 +473300,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0015152 gland of ocular region - + - + inferred @@ -473858,7 +473848,7 @@ https://doi.org/10.1515/9783110264043 - + A basement membrane of epithelium that is part of a respiratory system. EMAPA:37570 MA:0001815 @@ -473866,14 +473856,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0015329 respiratory system basement membrane - + - + MA @@ -474037,7 +474027,7 @@ https://doi.org/10.1515/9783110264043 - + The hepatic artery proper (also proper hepatic artery), arises from the common hepatic artery and runs alongside the portal vein and the common bile duct to form the portal triad. The hepatic artery proper gives off a small supraduodenal artery to the duodenal bulb. Then the right gastric artery comes off and runs to the left along the lesser curvature of the stomach to meet the left gastric artery, which is a branch of the celiac trunk. It subsequently gives off the cystic artery, which feeds the gallbladder, before bifurcating into the right and left hepatic arteries. Of note, the right and left hepatic arteries may demonstrate variant anatomy. A replaced right hepatic artery may arise from the superior mesenteric artery (SMA) and a replaced left hepatic artery may arise from the left gastric artery. EMAPA:37217 @@ -474052,7 +474042,7 @@ https://doi.org/10.1515/9783110264043 proper hepatic artery - + @@ -474065,7 +474055,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -474102,13 +474092,13 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -474128,14 +474118,14 @@ https://doi.org/10.1515/9783110264043 left hepatic artery - + - + FMA @@ -474180,13 +474170,13 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -474206,14 +474196,14 @@ https://doi.org/10.1515/9783110264043 right hepatic artery - + - + FMA @@ -474622,7 +474612,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a duodenum. EMAPA:27255 @@ -474636,14 +474626,14 @@ https://doi.org/10.1515/9783110264043 duodenum lamina propria - + - + FMA @@ -475747,7 +475737,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -475770,7 +475760,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0016887 entire extraembryonic component - + @@ -475783,7 +475773,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -476609,7 +476599,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -476627,14 +476617,14 @@ https://doi.org/10.1515/9783110264043 skeletal musculature - + - + MA @@ -478109,7 +478099,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -478123,14 +478113,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0034710 spinal cord ventricular layer - + - + EHDAA2 @@ -479466,8 +479456,8 @@ https://doi.org/10.1515/9783110264043 - - + + The parietal pleura that lines the mediastinum. FMA:9736 NCIT:C94820 @@ -479481,24 +479471,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0035431 mediastinal pleura - + - + - + FMA - + FMA @@ -479628,7 +479618,7 @@ https://doi.org/10.1515/9783110264043 - + Any of several arteries that arise from the aorta and supply blood to the esophagus. FMA:4149 @@ -479642,7 +479632,7 @@ https://doi.org/10.1515/9783110264043 esophageal artery - + @@ -479655,7 +479645,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -480263,7 +480253,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -480279,14 +480269,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0035763 cavity of cardiac chamber - + - + FMA @@ -480684,7 +480674,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -480700,14 +480690,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0035956 epididymal lumen - + - + FMA @@ -480815,20 +480805,20 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004070 uberon UBERON:0036072 respiratory primordium epithelium - + - + EHDAA2 @@ -480856,21 +480846,21 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004071 respiratory primordium associated mesenchyme uberon UBERON:0036073 respiratory primordium mesenchyme - + - + EHDAA2 @@ -481433,12 +481423,12 @@ https://doi.org/10.1515/9783110264043 - + - + Wall of ventricle which is continuous with the wall of aorta. FMA:9556 left ventricular wall @@ -481446,7 +481436,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0036285 wall of left ventricle - + @@ -481459,7 +481449,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -481484,12 +481474,12 @@ https://doi.org/10.1515/9783110264043 - + - + Wall of ventricle which is continuous with the wall of pulmonary trunk. FMA:9533 right ventricular wall @@ -481497,7 +481487,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0036286 wall of right ventricle - + @@ -481510,7 +481500,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -481543,7 +481533,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -481555,14 +481545,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0036288 anterior wall of left ventricle - + - + FMA @@ -481709,7 +481699,7 @@ https://doi.org/10.1515/9783110264043 - + The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. NCIT:C54419 @@ -481720,14 +481710,14 @@ https://doi.org/10.1515/9783110264043 renal pelvis/ureter - + - + NCIT @@ -481831,27 +481821,27 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:14657 gallbladder wall uberon UBERON:0036343 wall of gallbladder - + - + FMA @@ -481870,19 +481860,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:15089 brachiocephalic arterial wall uberon UBERON:0036351 wall of brachiocephalic artery - + @@ -481895,7 +481885,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -481914,19 +481904,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:15090 subclavian arterial wall uberon UBERON:0036352 wall of subclavian artery - + @@ -481939,7 +481929,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -481958,7 +481948,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -481968,21 +481958,21 @@ https://doi.org/10.1515/9783110264043 - + FMA:15704 anal canal wall uberon UBERON:0036362 wall of anal canal - + - + FMA @@ -482001,19 +481991,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:15889 right ureteral wall uberon UBERON:0036375 wall of right ureter - + @@ -482026,7 +482016,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482045,12 +482035,12 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:15890 left ureteral wall @@ -482059,7 +482049,7 @@ https://doi.org/10.1515/9783110264043 wall of left ureter - + @@ -482072,7 +482062,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482091,19 +482081,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:18211 pulmonary arterial wall uberon UBERON:0036422 wall of pulmonary artery - + @@ -482116,7 +482106,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482135,14 +482125,14 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:18303 uterine tube wall wall of fallopian tube @@ -482151,7 +482141,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0036441 wall of uterine tube - + @@ -482164,7 +482154,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482195,20 +482185,20 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:19779 urethral wall uberon UBERON:0036521 wall of urethra - + @@ -482221,7 +482211,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482240,19 +482230,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:231590 uberon UBERON:0036553 wall of synovial tendon sheath - + @@ -482265,7 +482255,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482278,20 +482268,20 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:58098 eyeball wall uberon UBERON:0036925 wall of eyeball - + @@ -482304,7 +482294,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482323,21 +482313,21 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:63144 orbit wall uberon UBERON:0037089 wall of orbit - + @@ -482350,7 +482340,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482369,19 +482359,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:66284 common carotid arterial wall uberon UBERON:0037094 wall of common carotid artery - + @@ -482394,7 +482384,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482413,7 +482403,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -482425,9 +482415,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees. FMA:7274 cardiac wall @@ -482435,15 +482425,15 @@ https://doi.org/10.1515/9783110264043 UBERON:0037144 wall of heart - + - + - + @@ -482456,19 +482446,19 @@ https://doi.org/10.1515/9783110264043 - + FMA - + FMA - + FMA @@ -482493,19 +482483,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:19676 male urethral wall uberon UBERON:0037447 wall of male urethra - + @@ -482518,7 +482508,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482537,19 +482527,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:19780 female urethral wall uberon UBERON:0037455 wall of female urethra - + @@ -482562,7 +482552,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482590,7 +482580,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -482606,14 +482596,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + FMA Wikipedia @@ -482660,20 +482650,20 @@ https://doi.org/10.1515/9783110264043 - + FMA:15395 uberon UBERON:0039228 sigmoid vein - + - + FMA @@ -482790,21 +482780,21 @@ https://doi.org/10.1515/9783110264043 - + A vein that drains the urethra. FMA:21270 uberon UBERON:0039377 urethral vein - + - + FMA @@ -482837,14 +482827,14 @@ https://doi.org/10.1515/9783110264043 - + Ovarian vein, each instance of which is a tributary of some inferior vena cava that drains the right pampiniform plexus of some broad ligament. FMA:14342 uberon UBERON:0039856 right ovarian vein - + @@ -482857,7 +482847,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -484072,8 +484062,8 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - - + + A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles. Purkinje fibre network @@ -484081,11 +484071,11 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 UBERON:8000009 Purkinje fiber network - + - + @@ -484100,7 +484090,7 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + https://github.com/obophenotype/uberon/issues/1785 https://orcid.org/0000-0001-5208-3432 https://orcid.org/0000-0002-9791-0064 @@ -484108,7 +484098,7 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + https://github.com/obophenotype/uberon/issues/1785 https://orcid.org/0000-0001-5208-3432 https://orcid.org/0000-0002-9791-0064 @@ -486264,14 +486254,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + - + @@ -486285,14 +486275,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + PMID:16417468 - + @@ -486396,14 +486386,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + ZFS - + @@ -486432,14 +486422,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -486453,14 +486443,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -486489,14 +486479,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + vertebrates - + @@ -486675,14 +486665,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA-abduced-lr - + @@ -486696,14 +486686,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + definitional - + @@ -486717,14 +486707,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest - + @@ -486783,14 +486773,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + only in species that have a stomach - + @@ -486834,14 +486824,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Wikipedia:Vitelline_vein - + @@ -486900,14 +486890,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -486936,14 +486926,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Wikipedia:Vitelline_vein - + @@ -486957,15 +486947,15 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + may be present in other parts in other species FMA - + @@ -487054,15 +487044,15 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + right arch 4 in human embryology.ch - + @@ -487076,14 +487066,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487097,14 +487087,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Wikipedia:Vitelline_vein - + @@ -487118,14 +487108,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Wikipedia - + @@ -487139,14 +487129,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + PMID:22179203 - + @@ -487160,14 +487150,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487181,14 +487171,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487202,14 +487192,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487223,14 +487213,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487244,14 +487234,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487265,14 +487255,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487286,14 +487276,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487307,14 +487297,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487328,14 +487318,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487376,14 +487366,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487457,14 +487447,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest - + @@ -487478,14 +487468,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487499,14 +487489,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487520,14 +487510,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487558,14 +487548,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + cjm - + @@ -487611,14 +487601,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + PMID:16417468 - + @@ -487632,14 +487622,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + PMID:16417468 - + @@ -487653,14 +487643,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487674,15 +487664,15 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + AAO https://github.com/geneontology/go-ontology/issues/16143 - + @@ -487696,14 +487686,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + ISBN:9780878932504 - + @@ -487732,14 +487722,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + teleosts - + @@ -487753,14 +487743,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Mammals - + @@ -487774,14 +487764,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + conservatively place at deuterostome, excluding acoelomates - + @@ -487870,14 +487860,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -492036,13 +492026,13 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + - + @@ -493500,9 +493490,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -493511,9 +493501,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -493545,9 +493535,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493556,9 +493546,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493590,9 +493580,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493601,9 +493591,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493635,9 +493625,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493646,9 +493636,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493680,9 +493670,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493691,9 +493681,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493837,7 +493827,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493848,7 +493838,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493865,7 +493855,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493875,7 +493865,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493893,7 +493883,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493904,7 +493894,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493921,7 +493911,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493931,7 +493921,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -494080,9 +494070,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -494091,9 +494081,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -494168,9 +494158,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -494179,9 +494169,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + diff --git a/aism-simple.json b/aism-simple.json index 42b2db9..00998d0 100644 --- a/aism-simple.json +++ b/aism-simple.json @@ -37,9 +37,9 @@ "val" : "https://creativecommons.org/licenses/by/4.0/" }, { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-03-16" + "val" : "2024-05-11" } ], - "version" : "http://purl.obolibrary.org/obo/aism/releases/2024-03-16/aism-simple.json" + "version" : "http://purl.obolibrary.org/obo/aism/releases/2024-05-11/aism-simple.json" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/AISM_0000000", @@ -2792,11 +2792,11 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The anatomical space adjacent to two cuticular punctures." + "val" : "The distance between two cuticular punctures." }, "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000232", - "val" : "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" + "val" : "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" } ] } }, { @@ -7823,9 +7823,6 @@ }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "has_characteristic" - }, { - "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://github.com/oborel/obo-relations/pull/284" } ] } }, { diff --git a/aism-simple.obo b/aism-simple.obo index 14fb7d6..efd3a1b 100644 --- a/aism-simple.obo +++ b/aism-simple.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: aism/releases/2024-03-16/aism-simple.owl +data-version: aism/releases/2024-05-11/aism-simple.owl subsetdef: AISM:0000171 "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_gp2term "" @@ -20,7 +20,7 @@ property_value: http://purl.org/dc/elements/1.1/contributor "István Mikó (imik property_value: http://purl.org/dc/elements/1.1/contributor "Jennifer C. Girón (jgiron) https://orcid.org/0000-0002-0851-6883" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "Luis A. González Montaña (lagonzalezmo) https://orcid.org/0000-0002-9136-9932" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "Sergei Tarasov (starasov) https://orcid.org/0000-0001-5237-2330" xsd:string -property_value: owl:versionInfo "2024-03-16" xsd:string +property_value: owl:versionInfo "2024-05-11" xsd:string [Term] id: AISM:0000000 @@ -2176,8 +2176,8 @@ relationship: parallel_to AISM:0000377 {http://purl.org/dc/elements/1.1/contribu [Term] id: AISM:0000376 name: interpunctural distance {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} -def: "The anatomical space adjacent to two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} -property_value: curator_notes "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} +def: "The distance between two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} +property_value: curator_notes "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} [Term] id: AISM:0000377 @@ -5932,7 +5932,6 @@ property_value: IAO:0000116 "A bearer can have many dependents, and its dependen property_value: IAO:0000118 "bearer_of" xsd:string property_value: IAO:0000118 "is bearer of" xsd:string property_value: RO:0001900 RO:0001901 -property_value: seeAlso "https://github.com/oborel/obo-relations/pull/284" xsd:string is_inverse_functional: true [Typedef] diff --git a/aism-simple.owl b/aism-simple.owl index 34e2522..3e730c5 100644 --- a/aism-simple.owl +++ b/aism-simple.owl @@ -15,7 +15,7 @@ xmlns:subsets="http://purl.obolibrary.org/obo/ro/subsets#" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - + http://purl.obolibrary.org/obo/AISM_0000174 http://purl.obolibrary.org/obo/PATO_0000001 http://purl.obolibrary.org/obo/UBERON_0001062 @@ -27,7 +27,7 @@ The ontology for the Anatomy of the Insect SkeletoMuscular system (AISM) contains terms used to describe the cuticle - as a single anatomical structure - and the skeletal muscle system, to be used in insect biodiversity research. Ontology for the Anatomy of the Insect SkeletoMuscular system - 2024-03-16 + 2024-05-11 @@ -1042,8 +1042,6 @@ A continuant cannot have an occurrent as part: use 'participates in'. RO:0000053 has_characteristic has characteristic - has characteristic - https://github.com/oborel/obo-relations/pull/284 @@ -16140,21 +16138,31 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 - The anatomical space adjacent to two cuticular punctures. - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + The distance between two cuticular punctures. + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 interpunctural distance - The anatomical space adjacent to two cuticular punctures. + The distance between two cuticular punctures. gmontanaro https://orcid.org/0000-0003-0836-1364 2023-06-04 - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 jgiron https://orcid.org/0000-0002-0851-6883 2024-02-14 diff --git a/aism.json b/aism.json index da30582..2855fcd 100644 --- a/aism.json +++ b/aism.json @@ -37,9 +37,9 @@ "val" : "https://creativecommons.org/licenses/by/4.0/" }, { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-03-16" + "val" : "2024-05-11" } ], - "version" : "http://purl.obolibrary.org/obo/aism/releases/2024-03-16/aism.json" + "version" : "http://purl.obolibrary.org/obo/aism/releases/2024-05-11/aism.json" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/IAO_0000002", @@ -3161,11 +3161,11 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The anatomical space adjacent to two cuticular punctures." + "val" : "The distance between two cuticular punctures." }, "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000232", - "val" : "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" + "val" : "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" } ] } }, { @@ -158479,9 +158479,6 @@ }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "has_characteristic" - }, { - "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", - "val" : "https://github.com/oborel/obo-relations/pull/284" } ] } }, { @@ -164349,6 +164346,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000232", "val" : "See github ticket https://github.com/oborel/obo-relations/issues/497" + }, { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0001-9625-1899" + }, { + "pred" : "http://purl.org/dc/terms/contributor", + "val" : "https://orcid.org/0000-0003-2620-0345" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2021-11-08T12:00:00Z" @@ -305123,10 +305126,6 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0008150", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/BFO_0000015" - }, { - "sub" : "http://purl.obolibrary.org/obo/GO_0008150", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/GO_0003674" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0008152", "pred" : "is_a", @@ -315350,7 +315349,7 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0042391", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/BFO_0000015" + "obj" : "http://purl.obolibrary.org/obo/BFO_0000003" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0042391", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", @@ -332731,6 +332730,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0099738", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/GO_0005938" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0100001", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/BFO_0000015" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0100001", "pred" : "is_a", @@ -426416,10 +426419,6 @@ "sub" : "http://purl.obolibrary.org/obo/BFO_0000004", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000004" - }, { - "sub" : "http://purl.obolibrary.org/obo/BFO_0000015", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", - "obj" : "http://purl.obolibrary.org/obo/BFO_0000015" }, { "sub" : "http://purl.obolibrary.org/obo/BFO_0000017", "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", @@ -426437,13 +426436,6 @@ "pred" : "http://purl.obolibrary.org/obo/BFO_0000050", "obj" : "http://purl.obolibrary.org/obo/BFO_0000031" } ] - }, { - "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "allValuesFromEdges" : [ { - "sub" : "http://purl.obolibrary.org/obo/BFO_0000020", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/BFO_0000020" - } ] }, { "predicateId" : "http://purl.obolibrary.org/obo/RO_0002162", "allValuesFromEdges" : [ { @@ -426883,7 +426875,7 @@ "rangeClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ] }, { "predicateId" : "http://purl.obolibrary.org/obo/RO_0000057", - "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003", "http://purl.obolibrary.org/obo/BFO_0000015" ], + "domainClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000003" ], "rangeClassIds" : [ "http://purl.obolibrary.org/obo/BFO_0000002" ] }, { "predicateId" : "http://purl.obolibrary.org/obo/RO_0000079", diff --git a/aism.obo b/aism.obo index 009bdb4..d52a816 100644 --- a/aism.obo +++ b/aism.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: releases/2024-03-16 +data-version: releases/2024-05-11 subsetdef: 1_STAR "" subsetdef: 2_STAR "" subsetdef: 3_STAR "" @@ -100,7 +100,7 @@ property_value: http://purl.org/dc/elements/1.1/contributor "István Mikó (imik property_value: http://purl.org/dc/elements/1.1/contributor "Jennifer C. Girón (jgiron) https://orcid.org/0000-0002-0851-6883" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "Luis A. González Montaña (lagonzalezmo) https://orcid.org/0000-0002-9136-9932" xsd:string property_value: http://purl.org/dc/elements/1.1/contributor "Sergei Tarasov (starasov) https://orcid.org/0000-0001-5237-2330" xsd:string -property_value: owl:versionInfo "2024-03-16" xsd:string +property_value: owl:versionInfo "2024-05-11" xsd:string [Term] id: AISM:0000000 @@ -2353,8 +2353,8 @@ relationship: parallel_to AISM:0000377 {http://purl.org/dc/elements/1.1/contribu [Term] id: AISM:0000376 name: interpunctural distance {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} -def: "The anatomical space adjacent to two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} -property_value: curator_notes "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} +def: "The distance between two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"} +property_value: curator_notes "Edited by jgiron https://orcid.org/0000-0002-0851-6883 \n2024-05-11\nTo make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of'\nMatching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318\n\nFormer definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} [Term] id: AISM:0000377 @@ -6014,7 +6014,6 @@ def: "An occurrent that has temporal proper parts and for some time t, p s-depen def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. is_a: BFO:0000003 ! occurrent -relationship: part_of BFO:0000015 {all_only="true"} ! process property_value: BFO:0000179 "process" xsd:string property_value: BFO:0000180 "Process" xsd:string property_value: editor_note "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string @@ -6096,7 +6095,6 @@ def: "b is a specifically dependent continuant = Def. b is a continuant & there comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000031 ! generically dependent continuant -relationship: has_part BFO:0000020 {all_only="true"} ! characteristic relationship: part_of BFO:0000020 {all_only="true"} ! characteristic property_value: BFO:0000179 "sdc" xsd:string property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string @@ -29154,7 +29152,6 @@ synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process is_a: BFO:0000015 ! process -relationship: has_part GO:0003674 ! molecular_function property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI created_by: jl creation_date: 2012-09-19T15:05:24Z @@ -41513,7 +41510,7 @@ id: GO:0042391 name: regulation of membrane potential namespace: biological_process def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732] -is_a: BFO:0000015 ! process +is_a: BFO:0000003 ! occurrent relationship: has_part GO:0034220 ! monoatomic ion transmembrane transport [Term] @@ -62501,6 +62498,7 @@ id: GO:0100001 name: regulation of skeletal muscle contraction by action potential namespace: biological_process def: "Any action potential process that regulates skeletal muscle contraction." [GOC:cjm, GOC:obol] +is_a: BFO:0000015 ! process is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: regulates GO:0003009 ! skeletal muscle contraction @@ -136246,6 +136244,8 @@ synonym: "utilizes" BROAD [] xref: RO:0017001 property_value: curator_notes "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input." xsd:string property_value: curator_notes "See github ticket https://github.com/oborel/obo-relations/issues/497" xsd:string +property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9625-1899 +property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2620-0345 property_value: IAO:0000112 "A diagnostic testing device utilizes a specimen." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0001-9625-1899 property_value: IAO:0000117 https://orcid.org/0000-0003-2620-0345 @@ -136764,7 +136764,6 @@ property_value: IAO:0000112 "this vase is bearer of this fragility" xsd:string property_value: IAO:0000118 "bearer_of" xsd:string property_value: IAO:0000118 "is bearer of" xsd:string property_value: RO:0001900 RO:0001901 -property_value: seeAlso "https://github.com/oborel/obo-relations/pull/284" xsd:string range: BFO:0000020 ! characteristic is_inverse_functional: true @@ -137081,7 +137080,6 @@ property_value: IAO:0000112 "this investigation has participant this investigato property_value: IAO:0000112 "this process has participant this input material (or this output material)" xsd:string property_value: IAO:0000118 "has_participant" xsd:string domain: BFO:0000003 ! occurrent -domain: BFO:0000015 ! process range: BFO:0000002 ! continuant holds_over_chain: has_part has_participant diff --git a/aism.owl b/aism.owl index 16b338b..0d05a14 100644 --- a/aism.owl +++ b/aism.owl @@ -42,7 +42,7 @@ xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#" xmlns:caloha-reqs-vetted="http://purl.obolibrary.org/obo/caloha-reqs-vetted#"> - + http://purl.obolibrary.org/obo/AISM_0000174 http://purl.obolibrary.org/obo/PATO_0000001 http://purl.obolibrary.org/obo/UBERON_0001062 @@ -54,7 +54,7 @@ The ontology for the Anatomy of the Insect SkeletoMuscular system (AISM) contains terms used to describe the cuticle - as a single anatomical structure - and the skeletal muscle system, to be used in insect biodiversity research. Ontology for the Anatomy of the Insect SkeletoMuscular system - 2024-03-16 + 2024-05-11 @@ -3148,9 +3148,7 @@ every c that is a concretization of g specifically denotes r RO:0000053 has_characteristic - has characteristic has characteristic - https://github.com/oborel/obo-relations/pull/284 @@ -3181,7 +3179,6 @@ every c that is a concretization of g specifically denotes r - @@ -3198,7 +3195,6 @@ every c that is a concretization of g specifically denotes r http://www.obofoundry.org/ro/#OBO_REL:has_participant RO:0000057 has_participant - has participant has participant @@ -5628,7 +5624,6 @@ Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.RO:0002333 enabled_by - enabled by enabled by https://wiki.geneontology.org/Enabled_by @@ -7853,6 +7848,8 @@ For example, A and B may be gene products and binding of B by A positively regul A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input. See github ticket https://github.com/oborel/obo-relations/issues/497 + + 2021-11-08T12:00:00Z 2021-11-08T12:00:00Z utilizes @@ -25810,15 +25807,20 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 - The anatomical space adjacent to two cuticular punctures. - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + The distance between two cuticular punctures. + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 interpunctural distance - + - + @@ -25833,14 +25835,19 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 - The anatomical space adjacent to two cuticular punctures. + The distance between two cuticular punctures. gmontanaro https://orcid.org/0000-0003-0836-1364 2023-06-04 - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 jgiron https://orcid.org/0000-0002-0851-6883 2024-02-14 @@ -53910,12 +53917,6 @@ starasov https://orcid.org/0000-0001-5237-2330 - - - - - - process Process a process of cell-division, \ a beating of the heart @@ -54113,12 +54114,6 @@ starasov https://orcid.org/0000-0001-5237-2330 - - - - - - sdc SpecificallyDependentContinuant @@ -98895,21 +98890,21 @@ The modern definition of neurosecretion has evolved to include the release of an - + An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion. https://orcid.org/0000-0002-1425-877X 2023-10-13T11:22:42Z UB cell ureteric bud cell - + - + PMID:9374839 @@ -114880,7 +114875,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -114905,14 +114900,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0005319 lipid transporter activity - + - + GO_REF:0000090 @@ -114993,7 +114988,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -115014,14 +115009,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0005326 neurotransmitter transmembrane transporter activity - + - + GO_REF:0000090 @@ -115250,32 +115245,32 @@ The modern definition of neurosecretion has evolved to include the release of an + - A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -124820,12 +124815,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - - - A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. A process that emerges from two or more causally-connected macromolecular activities and has evolved to achieve a biological objective. @@ -125336,7 +125325,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + Enables the transfer of a protein from one side of a membrane to the other. GO:0015266 GO:0015463 @@ -125365,14 +125354,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0008320 protein transmembrane transporter activity - + - + GO_REF:0000090 @@ -136630,7 +136619,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -136645,14 +136634,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015075 monoatomic ion transmembrane transporter activity - + - + GO_REF:0000090 @@ -136943,7 +136932,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -136966,14 +136955,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015114 phosphate ion transmembrane transporter activity - + - + GO_REF:0000090 @@ -137007,7 +136996,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137031,14 +137020,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015116 sulfate transmembrane transporter activity - + - + GO_REF:0000090 @@ -137083,7 +137072,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137095,14 +137084,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015123 acetate transmembrane transporter activity - + - + GO_REF:0000090 @@ -137277,7 +137266,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137292,14 +137281,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015144 carbohydrate transmembrane transporter activity - + - + GO_REF:0000090 @@ -137371,7 +137360,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137385,14 +137374,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015149 hexose transmembrane transporter activity - + - + GO_REF:0000090 @@ -137477,7 +137466,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -137541,14 +137530,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:0015171 amino acid transmembrane transporter activity - + - + GO_REF:0000090 @@ -164542,7 +164531,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -229702,6 +229691,7 @@ The modern definition of neurosecretion has evolved to include the release of an + @@ -243635,7 +243625,7 @@ The modern definition of neurosecretion has evolved to include the release of an - + @@ -243650,14 +243640,14 @@ The modern definition of neurosecretion has evolved to include the release of an GO:1901505 carbohydrate derivative transmembrane transporter activity - + - + GO_REF:0000090 @@ -313393,9 +313383,9 @@ When there is no such string, it is almost always because the entities take the - - - + + + @@ -313439,34 +313429,34 @@ When there is no such string, it is almost always because the entities take the islet of Langerhans http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png - + - + - + - + PMID:16417468 - + PMID:16417468 - + PMID:16417468 @@ -313774,7 +313764,7 @@ When there is no such string, it is almost always because the entities take the - + @@ -313820,7 +313810,7 @@ When there is no such string, it is almost always because the entities take the sympathetic nervous system http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png - + @@ -313833,7 +313823,7 @@ When there is no such string, it is almost always because the entities take the - + FMA MA ZFA-modified-from-isa @@ -314039,7 +314029,7 @@ When there is no such string, it is almost always because the entities take the - + @@ -314052,9 +314042,9 @@ When there is no such string, it is almost always because the entities take the - - - + + + @@ -314102,19 +314092,19 @@ When there is no such string, it is almost always because the entities take the endocrine pancreas - + - + - + - + @@ -314127,7 +314117,7 @@ When there is no such string, it is almost always because the entities take the - + AAO FMA XAO @@ -314135,19 +314125,19 @@ When there is no such string, it is almost always because the entities take the - + GO - + GO - + GO @@ -314358,7 +314348,7 @@ When there is no such string, it is almost always because the entities take the - + @@ -314386,14 +314376,14 @@ When there is no such string, it is almost always because the entities take the compound eye https://github.com/obophenotype/uberon/issues/457 - + - + PMID:21062451 @@ -314475,7 +314465,7 @@ When there is no such string, it is almost always because the entities take the - + @@ -314516,14 +314506,14 @@ When there is no such string, it is almost always because the entities take the camera-type eye - + - + definitional @@ -314961,7 +314951,7 @@ When there is no such string, it is almost always because the entities take the - + A lamina propria that is part of a respiratory airway. EMAPA:35877 FMA:265157 @@ -314984,14 +314974,14 @@ When there is no such string, it is almost always because the entities take the UBERON:0000031 lamina propria of trachea - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -315302,8 +315292,8 @@ When there is no such string, it is almost always because the entities take the - - + + @@ -315354,11 +315344,11 @@ When there is no such string, it is almost always because the entities take the tendon http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg - + - + @@ -315371,13 +315361,13 @@ When there is no such string, it is almost always because the entities take the - + OG - + AEO @@ -315452,8 +315442,8 @@ When there is no such string, it is almost always because the entities take the - - + + A biological tissue mass, most commonly a mass of nerve cell bodies. TODO - check vert vs invert. Other species: Any of a number of aggregations of neurons, glial cells and their processes, surrounded by a glial cell and connective tissue sheath (plural: ganglia). // Subdivision of neural tree (organ) which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord); together with a nucleus and its associated nerve, it constitutes a neural tree (organ). Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. // a cluster of nerve cells and associated glial cells (nuclear location) // Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system. @@ -315505,11 +315495,11 @@ When there is no such string, it is almost always because the entities take the ganglion - + - + @@ -315522,13 +315512,13 @@ When there is no such string, it is almost always because the entities take the - + EHDAA2 - + Bgee:AN @@ -315720,7 +315710,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -315780,14 +315770,14 @@ https://doi.org/10.1515/9783110264043 ureter https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + GO @@ -315859,8 +315849,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -315910,25 +315900,25 @@ https://doi.org/10.1515/9783110264043 urethra https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png - + - + - + pelvic part of UG sinus gives rise to prostatic and membranous parts of urethra Wikipedia - + Wikipedia @@ -316471,7 +316461,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -316492,14 +316482,14 @@ https://doi.org/10.1515/9783110264043 respiratory tract - + - + NCBIBook:NBK10107 @@ -317162,7 +317152,7 @@ https://doi.org/10.1515/9783110264043 - + The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube) @@ -317188,7 +317178,7 @@ https://doi.org/10.1515/9783110264043 external ectoderm http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png - + @@ -317201,7 +317191,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -317625,15 +317615,15 @@ https://doi.org/10.1515/9783110264043 - - + + - + @@ -317669,34 +317659,34 @@ https://doi.org/10.1515/9783110264043 metanephros - + - + - + - + definitional - + GO - + ISBN:9780878932504 @@ -317852,8 +317842,8 @@ https://doi.org/10.1515/9783110264043 - - + + An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]. Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG] Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts[VHOG:0000541]. @@ -317880,11 +317870,11 @@ https://doi.org/10.1515/9783110264043 ureteric bud - + - + @@ -317897,13 +317887,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + ISBN:9780878932504 @@ -317989,7 +317979,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -318032,14 +318022,14 @@ https://doi.org/10.1515/9783110264043 morula http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png - + - + EHDAA2 @@ -318196,8 +318186,8 @@ https://doi.org/10.1515/9783110264043 - - + + A mass of cells that develop into the body of the embryo and some extraembryonic tissues. A group of cells found in the mammalian blastocyst that give rise to the embryo. [Biology_Online][VHOG] A small sphere of cells known as the inner cell mass lies within the trophoblast (of all eutherian mammals).[well established][VHOG] @@ -318225,24 +318215,24 @@ https://doi.org/10.1515/9783110264043 inner cell mass https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg - + - + - + Wikipedia - + Wikipedia @@ -318309,7 +318299,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -318342,14 +318332,14 @@ https://doi.org/10.1515/9783110264043 trophoblast https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg - + - + MP-def PMID:19829370 @@ -318415,7 +318405,7 @@ https://doi.org/10.1515/9783110264043 - + A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc. embryonic disc embryonic shield @@ -318435,14 +318425,14 @@ https://doi.org/10.1515/9783110264043 bilaminar disc http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png - + - + Wikipedia @@ -318543,7 +318533,7 @@ https://doi.org/10.1515/9783110264043 - + Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. 2009-07-30T05:19:13Z @@ -318554,14 +318544,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0000094 membrane organ - + - + FMA-def @@ -318584,7 +318574,7 @@ https://doi.org/10.1515/9783110264043 - + Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]. A subpopulation of the cephalic neural crest that emerges from the otic level to the anterior limit of somite 4. It migrates to the heart and is essential for the septation of the outflow track[DOI:10.1242/dev.091751]. ZFA treats this as a subtype of NC. @@ -318601,14 +318591,14 @@ https://doi.org/10.1515/9783110264043 cardiac neural crest - + - + Wikipedia @@ -319075,7 +319065,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -319111,14 +319101,14 @@ https://doi.org/10.1515/9783110264043 gastrula stage - + - + BILS @@ -319637,7 +319627,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -319665,7 +319655,7 @@ https://doi.org/10.1515/9783110264043 lung bud http://upload.wikimedia.org/wikipedia/commons/7/71/Gray948.png - + @@ -319678,7 +319668,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -319790,7 +319780,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -319816,14 +319806,14 @@ https://doi.org/10.1515/9783110264043 neural nucleus - + - + we limit this structure by definition to chordate and vertebrate nervous systems @@ -320040,7 +320030,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -320079,14 +320069,14 @@ https://doi.org/10.1515/9783110264043 anal canal https://upload.wikimedia.org/wikipedia/commons/0/01/Gray1078.png - + - + Wikipathways:WP2062 @@ -320269,8 +320259,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -320303,24 +320293,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0000162 cloaca - + - + - + ZFA - + AAO @@ -320402,8 +320392,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -320422,24 +320412,24 @@ https://doi.org/10.1515/9783110264043 embryonic cloaca - + - + - + EHDAA2 - + EHDAA2 @@ -320462,7 +320452,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -320504,14 +320494,14 @@ https://doi.org/10.1515/9783110264043 primitive urogenital sinus http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + - + MP-def @@ -321067,7 +321057,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -321113,14 +321103,14 @@ https://doi.org/10.1515/9783110264043 pair of lungs - + - + FMA-abduced @@ -321295,21 +321285,21 @@ https://doi.org/10.1515/9783110264043 - + - + - + A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. @@ -321353,34 +321343,34 @@ https://doi.org/10.1515/9783110264043 blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -321496,7 +321486,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -321531,7 +321521,7 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/9/97/Gray136.png https://upload.wikimedia.org/wikipedia/commons/5/5b/Frontal_bone.png - + @@ -321544,7 +321534,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -321747,7 +321737,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -321780,14 +321770,14 @@ https://doi.org/10.1515/9783110264043 atlanto-occipital joint http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png - + - + FMA-abduced-lr @@ -322243,7 +322233,7 @@ https://doi.org/10.1515/9783110264043 - + The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin. BTO:0000503 EMAPA:27181 @@ -322254,7 +322244,7 @@ https://doi.org/10.1515/9783110264043 gastric gland - + @@ -322267,7 +322257,7 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0073040584 @@ -323219,7 +323209,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -323246,7 +323236,7 @@ https://doi.org/10.1515/9783110264043 syncytiotrophoblast http://upload.wikimedia.org/wikipedia/commons/d/df/Gray36.png - + @@ -323259,7 +323249,7 @@ https://doi.org/10.1515/9783110264043 - + EMAPA @@ -324622,7 +324612,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -324664,14 +324654,14 @@ https://doi.org/10.1515/9783110264043 organism substance - + - + this relationship may be too strong and may be weakened in future @@ -325922,7 +325912,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -325966,14 +325956,14 @@ https://doi.org/10.1515/9783110264043 epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -326574,7 +326564,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -326611,14 +326601,14 @@ https://doi.org/10.1515/9783110264043 abdomen - + - + MA @@ -326881,7 +326871,7 @@ https://doi.org/10.1515/9783110264043 - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -326919,14 +326909,14 @@ https://doi.org/10.1515/9783110264043 ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -326991,7 +326981,7 @@ https://doi.org/10.1515/9783110264043 - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -327028,14 +327018,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -327102,7 +327092,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327153,7 +327143,7 @@ https://doi.org/10.1515/9783110264043 mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -327166,7 +327156,7 @@ https://doi.org/10.1515/9783110264043 - + Bgee:AN @@ -327377,7 +327367,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327427,7 +327417,7 @@ https://doi.org/10.1515/9783110264043 proctodeum https://github.com/obophenotype/uberon/issues/685 - + @@ -327440,7 +327430,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -327513,7 +327503,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327554,7 +327544,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327634,11 +327624,11 @@ https://doi.org/10.1515/9783110264043 stomach https://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg - + - + @@ -327657,14 +327647,14 @@ https://doi.org/10.1515/9783110264043 - + absent in lampreys and hagfishes ISBN:0073040584 - + ISBN:0486692132 @@ -327758,7 +327748,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -327807,7 +327797,7 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb https://upload.wikimedia.org/wikipedia/commons/9/91/Aorta_scheme.jpg - + @@ -327820,7 +327810,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -327900,7 +327890,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -328009,14 +327999,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + MA @@ -328212,7 +328202,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -328243,7 +328233,7 @@ https://doi.org/10.1515/9783110264043 - + The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. requires review for applicability to invertebrate structures, e.g. synganglion @@ -328307,11 +328297,11 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb - + - + @@ -328324,13 +328314,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + Bgee:AN @@ -328583,9 +328573,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -328610,7 +328600,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -328666,44 +328656,44 @@ https://doi.org/10.1515/9783110264043 cornea http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + - + MA - + MA - + FMA-isa - + definitional @@ -328893,9 +328883,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -328906,7 +328896,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -328963,44 +328953,44 @@ https://doi.org/10.1515/9783110264043 retina http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png - + - + - + - + - + FMA - + FMA - + FMA - + EHDAA2 @@ -329074,8 +329064,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -329111,24 +329101,24 @@ https://doi.org/10.1515/9783110264043 eye - + - + - + PMID:21062451 - + PMID:21062451 @@ -329305,7 +329295,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -329319,7 +329309,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -329386,14 +329376,14 @@ https://doi.org/10.1515/9783110264043 pleura http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png - + - + https://github.com/obophenotype/uberon/issues/86 @@ -329568,7 +329558,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -329637,14 +329627,14 @@ https://doi.org/10.1515/9783110264043 pons http://upload.wikimedia.org/wikipedia/commons/3/36/Gray768.png - + - + neuronames @@ -329713,8 +329703,8 @@ https://doi.org/10.1515/9783110264043 - - + + An intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination. penile phallic @@ -329750,11 +329740,11 @@ https://doi.org/10.1515/9783110264043 penis http://upload.wikimedia.org/wikipedia/commons/8/87/Labelled_flaccid_penis.jpg - + - + @@ -329767,13 +329757,13 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia - + EHDAA2 @@ -331084,7 +331074,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -331154,14 +331144,14 @@ https://doi.org/10.1515/9783110264043 vas deferens http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg - + - + FMA @@ -331293,7 +331283,7 @@ https://doi.org/10.1515/9783110264043 - + Tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Cuticles are non-homologous, differing in their origin, structure and chemical composition[WP]. cuticular BTO:0001600 @@ -331308,14 +331298,14 @@ https://doi.org/10.1515/9783110264043 EDITOR_NOTE TODO - check cuticle vs exoskeleton. Note that GO has a very generic definition of cuticle. See also arthropod-anatomy ontology. Note in ncit Cuticle is a plant part cuticle - + - + Rieger - Evolution of the Cuticle in the Lower Eumetazoa @@ -332454,7 +332444,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -332521,14 +332511,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -332638,7 +332628,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -332693,7 +332683,7 @@ https://doi.org/10.1515/9783110264043 central nervous system - + @@ -332707,7 +332697,7 @@ https://doi.org/10.1515/9783110264043 - + Bgee:AN @@ -332934,7 +332924,7 @@ https://doi.org/10.1515/9783110264043 - + A nerve that transmits from sensory receptors on the surface of the body to the central nervous system. AEO:0000201 EHDAA2:0003200 @@ -332949,14 +332939,14 @@ https://doi.org/10.1515/9783110264043 sensory nerve - + - + AEO @@ -333112,8 +333102,8 @@ https://doi.org/10.1515/9783110264043 - - + + A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. consider splitting class One of the extraembryonic fetal membranes that balloons out from the fetal midgut. [TFD][VHOG] @@ -333144,11 +333134,11 @@ https://doi.org/10.1515/9783110264043 yolk sac http://upload.wikimedia.org/wikipedia/commons/1/17/Gray22.png - + - + @@ -333167,13 +333157,13 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0073040584 - + ISBN:0073040584 @@ -333332,7 +333322,7 @@ https://doi.org/10.1515/9783110264043 - + A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]. A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNYX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx)[MESH:A03.867]. Anatomical cavity bounded by the derivatives of the branchial arches.[AAO] @@ -333374,14 +333364,14 @@ https://doi.org/10.1515/9783110264043 Consider generalizing to deuterostome pharynx chordate pharynx - + - + EHDAA2 @@ -333700,7 +333690,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -333737,14 +333727,14 @@ https://doi.org/10.1515/9783110264043 hindgut http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png - + - + Wikipedia @@ -334000,15 +333990,15 @@ https://doi.org/10.1515/9783110264043 - + - - + + @@ -334062,15 +334052,15 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb - + - + - + @@ -334084,19 +334074,19 @@ https://doi.org/10.1515/9783110264043 - + MA - + EHDAA2 - + ISBN:0073040584 @@ -334196,7 +334186,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -334243,7 +334233,7 @@ https://doi.org/10.1515/9783110264043 ventral pancreatic duct http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png - + @@ -334256,7 +334246,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -334341,7 +334331,7 @@ https://doi.org/10.1515/9783110264043 - + A zone of skin that is part of a back [Automatically generated definition]. EMAPA:36392 FMA:10462 @@ -334358,7 +334348,7 @@ https://doi.org/10.1515/9783110264043 EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region skin of back - + @@ -334371,7 +334361,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -334405,9 +334395,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]. not homologous to the external carotid of zebrafish (Goodrich, 1958) - http://zfish.nichd.nih.gov/zfatlas/Intro%20Page/comparative.html; check XAO @@ -334440,15 +334430,15 @@ https://doi.org/10.1515/9783110264043 https://sourceforge.net/tracker/?func=detail&aid=3486863&group_id=76834&atid=1127722 http://upload.wikimedia.org/wikipedia/commons/1/13/External_carotid_a.gif - + - + - + @@ -334461,19 +334451,19 @@ https://doi.org/10.1515/9783110264043 - + FMA - + EHDAA2 - + FMA @@ -334790,14 +334780,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -334838,11 +334828,11 @@ https://doi.org/10.1515/9783110264043 pericardial cavity - + - + @@ -334855,13 +334845,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + Wikipedia @@ -334934,7 +334924,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -334966,14 +334956,14 @@ https://doi.org/10.1515/9783110264043 endocardium of ventricle - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -335111,7 +335101,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -335139,14 +335129,14 @@ https://doi.org/10.1515/9783110264043 myocardium of ventricle - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -335657,7 +335647,7 @@ https://doi.org/10.1515/9783110264043 - + The second vertebral bone in the vertebral column. Vertebra that is posteriorly adjacent to vertebra 1.[TAO] @@ -335693,14 +335683,14 @@ https://doi.org/10.1515/9783110264043 vertebral bone 2 - + - + FMA @@ -336001,7 +335991,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -336018,7 +336008,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -336064,24 +336054,24 @@ https://doi.org/10.1515/9783110264043 diaphragm - + - + - + PMID:23586979 - + definitional @@ -336380,7 +336370,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -336461,14 +336451,14 @@ https://doi.org/10.1515/9783110264043 vertebral column - + - + cjm @@ -337155,7 +337145,7 @@ https://doi.org/10.1515/9783110264043 - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -337180,14 +337170,14 @@ https://doi.org/10.1515/9783110264043 mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -337302,7 +337292,7 @@ https://doi.org/10.1515/9783110264043 - + In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. BTO:0002783 @@ -337325,14 +337315,14 @@ https://doi.org/10.1515/9783110264043 superior mesenteric vein http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png - + - + Wikipedia:Vitelline_vein @@ -337374,7 +337364,7 @@ https://doi.org/10.1515/9783110264043 - + A vein that drains the pelvis and lower limbs into the inferior vena cava. In human anatomy, the common iliac veins are formed by the external iliac veins and internal iliac veins and together, in the abdomen at the level of the fifth lumbar vertebrae, form the inferior vena cava. They drain blood from the pelvis and lower limbs. Both common iliac veins are accompanied along their course by common iliac arteries. @@ -337397,7 +337387,7 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb https://upload.wikimedia.org/wikipedia/commons/6/65/Iliac_veins.gif - + @@ -337410,7 +337400,7 @@ https://doi.org/10.1515/9783110264043 - + FMA-abduced-lr @@ -337719,7 +337709,7 @@ https://doi.org/10.1515/9783110264043 - + Vein that carries blood away from the liver[ZFA]. todo - add developmental relationships for other taxa @@ -337750,14 +337740,14 @@ https://doi.org/10.1515/9783110264043 hepatic vein http://upload.wikimedia.org/wikipedia/commons/6/61/Gray1121.png - + - + FMA-abduced-lr @@ -338141,7 +338131,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -338177,7 +338167,7 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png - + @@ -338190,7 +338180,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -338238,7 +338228,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -338293,7 +338283,7 @@ https://doi.org/10.1515/9783110264043 colon - + @@ -338307,7 +338297,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -338372,7 +338362,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity. BTO:0000645 @@ -338404,7 +338394,7 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb - + @@ -338417,7 +338407,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -338522,7 +338512,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -338576,7 +338566,7 @@ https://doi.org/10.1515/9783110264043 pyloric antrum http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg - + @@ -338589,7 +338579,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -339093,7 +339083,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -339110,7 +339100,7 @@ https://doi.org/10.1515/9783110264043 portal lobule - + @@ -339123,7 +339113,7 @@ https://doi.org/10.1515/9783110264043 - + MA MP @@ -339147,7 +339137,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -339173,14 +339163,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001172 hepatic acinus - + - + cjm @@ -339416,16 +339406,16 @@ https://doi.org/10.1515/9783110264043 - - - + + + - + @@ -339454,19 +339444,19 @@ https://doi.org/10.1515/9783110264043 common hepatic duct http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg - + - + - + - + @@ -339479,25 +339469,25 @@ https://doi.org/10.1515/9783110264043 - + MA - + Wikipedia - + Wikipedia - + definitional @@ -339760,7 +339750,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -339802,14 +339792,14 @@ https://doi.org/10.1515/9783110264043 peritoneal cavity - + - + Wikipedia @@ -341932,8 +341922,8 @@ https://doi.org/10.1515/9783110264043 - - + + A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]. currently defined as equivalent to any submucosal gland in the duodenum. Said to be absent outside mammlian (Andrew 1959) but Ziswiler and Farner (1972) noted similar glands at the gastroduodenal junction of some birds @@ -341959,11 +341949,11 @@ https://doi.org/10.1515/9783110264043 duodenal gland - + - + @@ -341976,13 +341966,13 @@ https://doi.org/10.1515/9783110264043 - + FMA, modified - + unclear for Aves ISBN:9780521617147 @@ -342038,7 +342028,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -342084,7 +342074,7 @@ https://doi.org/10.1515/9783110264043 intestinal villus http://upload.wikimedia.org/wikipedia/commons/3/38/Small_intestine_low_mag.jpg - + @@ -342097,7 +342087,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -342210,7 +342200,7 @@ https://doi.org/10.1515/9783110264043 - + A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. BTO:0002782 @@ -342234,14 +342224,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + FMA/obol @@ -342389,14 +342379,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -342448,24 +342438,24 @@ https://doi.org/10.1515/9783110264043 renal pelvis https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg - + - + - + MA - + FMA @@ -342511,7 +342501,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -342548,14 +342538,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg - + - + FMA @@ -342584,11 +342574,11 @@ https://doi.org/10.1515/9783110264043 - + - - + + @@ -342627,7 +342617,7 @@ https://doi.org/10.1515/9783110264043 nephron tubule - + @@ -342636,18 +342626,18 @@ https://doi.org/10.1515/9783110264043 - + - + - + GO MA ZFA @@ -342661,13 +342651,13 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + checkme @@ -342708,7 +342698,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -342756,14 +342746,14 @@ https://doi.org/10.1515/9783110264043 collecting duct of renal tubule - + - + checkme GO @@ -343493,7 +343483,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -343525,7 +343515,7 @@ https://doi.org/10.1515/9783110264043 interlobular bile duct - + @@ -343539,7 +343529,7 @@ https://doi.org/10.1515/9783110264043 - + FMA MA MP @@ -343581,7 +343571,7 @@ https://doi.org/10.1515/9783110264043 - + An adventitia that is part of a ureter. EMAPA:28114 FMA:15892 @@ -343597,14 +343587,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001252 adventitia of ureter - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -343648,7 +343638,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a ureter [Automatically generated definition]. EMAPA:28841 @@ -343665,14 +343655,14 @@ https://doi.org/10.1515/9783110264043 lamina propria of ureter - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -343715,7 +343705,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -343726,7 +343716,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -343779,11 +343769,11 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urinary_Bladder.glb https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + @@ -343796,13 +343786,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + upper part of UG sinus @@ -344110,7 +344100,7 @@ https://doi.org/10.1515/9783110264043 - + A serous membrane that is part of a urinary bladder [Automatically generated definition]. TODO - check serosa/peritoneum EMAPA:28661 @@ -344133,14 +344123,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001260 serosa of urinary bladder - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -344429,7 +344419,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -344461,14 +344451,14 @@ https://doi.org/10.1515/9783110264043 pancreatic acinus - + - + FMA @@ -344517,9 +344507,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]. Organ which secretes a fluid containing enzymes that aid in the digestion of food.[AAO] @@ -344565,34 +344555,34 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Pancreas.glb https://upload.wikimedia.org/wikipedia/commons/7/7e/Blausen_0699_PancreasAnatomy2.png - + - + - + - + PMID:16417468 - + Wikipedia - + Wikipedia @@ -344657,7 +344647,7 @@ https://doi.org/10.1515/9783110264043 - + A trabecula that is part of a spleen. EMAPA:35808 @@ -344675,14 +344665,14 @@ https://doi.org/10.1515/9783110264043 trabecula of spleen - + - + FMA @@ -345267,7 +345257,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -345297,14 +345287,14 @@ https://doi.org/10.1515/9783110264043 liver parenchyma - + - + XAO @@ -345379,7 +345369,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -345429,14 +345419,14 @@ https://doi.org/10.1515/9783110264043 hepatic sinusoid - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -345501,8 +345491,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -345545,11 +345535,11 @@ https://doi.org/10.1515/9783110264043 intralobular bile duct - + - + @@ -345562,13 +345552,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + FMA @@ -345630,7 +345620,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -345643,7 +345633,7 @@ https://doi.org/10.1515/9783110264043 - + The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]. kidney terms require review for cross-vertebrate compatibility and developmental relationships. @@ -345676,24 +345666,24 @@ https://doi.org/10.1515/9783110264043 nephron http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + - + FMA - + Bgee:AN @@ -345762,7 +345752,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -345812,14 +345802,14 @@ https://doi.org/10.1515/9783110264043 endometrium https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg - + - + FMA @@ -345906,7 +345896,7 @@ https://doi.org/10.1515/9783110264043 - + Outer serosa layer of the uterus. TODO - check for parallel structure with peritoneum EMAPA:37792 @@ -345930,14 +345920,14 @@ https://doi.org/10.1515/9783110264043 serosa of uterus https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -346026,7 +346016,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -346056,14 +346046,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/1/13/Anteriorglanspenis.jpg https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png - + - + Bgee:AN @@ -346107,14 +346097,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -346169,24 +346159,24 @@ https://doi.org/10.1515/9783110264043 epididymis http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_testis_surface.jpg - + - + - + FMA - + Wikipedia @@ -346559,7 +346549,7 @@ https://doi.org/10.1515/9783110264043 - + Muscle (organ) which is a part of the pelvis. Examples: levator ani,. @@ -346577,7 +346567,7 @@ https://doi.org/10.1515/9783110264043 muscle of pelvis - + @@ -346589,7 +346579,7 @@ https://doi.org/10.1515/9783110264043 - + FMAdef @@ -346985,7 +346975,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -347030,14 +347020,14 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/4/49/Seminiferous_tubule_and_sperm_low_mag.jpg http://upload.wikimedia.org/wikipedia/commons/6/6a/Gray1145.png - + - + Wikipedia @@ -347116,7 +347106,7 @@ https://doi.org/10.1515/9783110264043 - + The anus and surrounding regions. Encompasses both internal and external regions, where present. Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG] EFO:0000847 @@ -347142,14 +347132,14 @@ https://doi.org/10.1515/9783110264043 https://github.com/obophenotype/uberon/issues/507 http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png - + - + cjm @@ -348013,7 +348003,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348024,7 +348014,7 @@ https://doi.org/10.1515/9783110264043 - + Skeletal element that is composed of bone tissue. @@ -348074,14 +348064,14 @@ https://doi.org/10.1515/9783110264043 bone element - + - + VSAO-modified @@ -348279,7 +348269,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348323,14 +348313,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + EHDAA2 @@ -348385,7 +348375,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a pelvic girdle [Automatically generated definition]. Note that in MA, this is a subclass of pelvis muscle; in FMA this is a hindlimb muscle, but recall in FMA hindlimb includes the girdle. UBERON:0003271 @@ -348407,14 +348397,14 @@ https://doi.org/10.1515/9783110264043 muscle of pelvic girdle - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -348484,7 +348474,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348532,14 +348522,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + left arch 4 in human embryology.ch @@ -348603,7 +348593,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348639,7 +348629,7 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + @@ -348652,7 +348642,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -348791,7 +348781,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -348840,14 +348830,14 @@ https://doi.org/10.1515/9783110264043 abdominal aorta http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png - + - + FMA @@ -349029,7 +349019,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -349067,7 +349057,7 @@ https://doi.org/10.1515/9783110264043 common carotid artery plus branches http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg - + @@ -349080,7 +349070,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -349158,8 +349148,8 @@ https://doi.org/10.1515/9783110264043 - - + + One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta. Developmental relationships should be added (intersegmental artery and right dorsal aorta in EHDAA2, occipitovertebral artery in XAO) @@ -349197,24 +349187,24 @@ https://doi.org/10.1515/9783110264043 subclavian artery http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg - + - + - + EHDAA2 - + EHDAA2 @@ -349403,7 +349393,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -349458,14 +349448,14 @@ https://doi.org/10.1515/9783110264043 digestive tract - + - + NCBIBook:NBK10107 @@ -349989,7 +349979,7 @@ https://doi.org/10.1515/9783110264043 - + The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. BTO:0000654 @@ -350012,7 +350002,7 @@ https://doi.org/10.1515/9783110264043 ciliary muscle http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png - + @@ -350031,7 +350021,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -350155,10 +350145,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + A sphincter muscle that is part of the iris. In humans, it functions to constrict the pupil in bright light or during accommodation. Its dimensions are about 0.75 mm wide by 0.15 mm thick. It is controlled by parasympathetic fibers that originate from the Edinger-Westphal nucleus, travel along the oculomotor nerve (CN III), synapse in the ciliary ganglion, and then enter the eye via the short ciliary nerves. Initially, all the myocytes are of the smooth muscle type, but much later in life, so that ultimately most cells are of the striated muscle type. [WP,unvetted] WP says: It is found in vertebrates and some cephalopods; this class refers to the vertebrate structure @@ -350193,19 +350183,19 @@ https://doi.org/10.1515/9783110264043 sphincter pupillae http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png - + - + - + - + @@ -350218,27 +350208,27 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0781772214 - + encircles iris dbpedia - + encircles iris dbpedia - + dbpedia @@ -350351,10 +350341,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]. It is innervated by the sympathetic system, which acts by releasing noradrenaline, which acts on alpha1-receptors. Thus, when presented with a threatening stimuli that activates the fight-or-flight response, this innervation dilates the iris, thus temporarily letting more light reach the retina @@ -350391,19 +350381,19 @@ https://doi.org/10.1515/9783110264043 dilatator pupillae http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png - + - + - + - + @@ -350416,27 +350406,27 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0781772214 - + outer margins of iris dbpedia - + inner margins of iris dbpedia - + dbpedia @@ -351130,10 +351120,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + The first major branch of the abdominal aorta. EHDAA2:0004519 @@ -351165,44 +351155,44 @@ https://doi.org/10.1515/9783110264043 celiac artery http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png - + - + - + - + - + ISBN:0073040584 - + ISBN:0073040584 - + ISBN:0073040584 - + ISBN:0073040584 @@ -351323,7 +351313,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -351385,14 +351375,14 @@ https://doi.org/10.1515/9783110264043 trigeminal nerve https://upload.wikimedia.org/wikipedia/commons/9/99/Gray778_Trigeminal.png - + - + Wikipedia @@ -351677,7 +351667,7 @@ https://doi.org/10.1515/9783110264043 - + The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]. Vein which collects blood from muscles of the head and drains into the external jugular vein.[AAO] @@ -351701,14 +351691,14 @@ https://doi.org/10.1515/9783110264043 facial vein http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png - + - + FMA @@ -351790,7 +351780,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -351851,7 +351841,7 @@ https://doi.org/10.1515/9783110264043 trigeminal ganglion http://upload.wikimedia.org/wikipedia/commons/6/69/Gray776.png - + @@ -351864,7 +351854,7 @@ https://doi.org/10.1515/9783110264043 - + Bgee:AN @@ -351988,11 +351978,11 @@ https://doi.org/10.1515/9783110264043 - - - - - + + + + + @@ -352023,23 +352013,23 @@ https://doi.org/10.1515/9783110264043 occipital bone http://upload.wikimedia.org/wikipedia/commons/2/27/Gray194.png - + - + - + - + - + @@ -352052,32 +352042,32 @@ https://doi.org/10.1515/9783110264043 - + FMA - + basi paired exo and supra occipital bones MA-modified - + interparietal (postparietal) - + WP - + PMID:11523816 @@ -352139,10 +352129,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended. part of viscerocranium (facial skeleton) in FMA @@ -352171,19 +352161,19 @@ https://doi.org/10.1515/9783110264043 sphenoid bone http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg - + - + - + - + @@ -352196,25 +352186,25 @@ https://doi.org/10.1515/9783110264043 - + orbito pre and basi sphenoid - + pterygoid process - + alisphenoid - + cjm @@ -352283,7 +352273,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -352319,7 +352309,7 @@ https://doi.org/10.1515/9783110264043 ethmoid bone http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg - + @@ -352332,7 +352322,7 @@ https://doi.org/10.1515/9783110264043 - + definitional @@ -352415,7 +352405,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -352448,14 +352438,14 @@ https://doi.org/10.1515/9783110264043 orbit of skull - + - + FMA-abduced-lr @@ -352632,7 +352622,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -352698,14 +352688,14 @@ https://doi.org/10.1515/9783110264043 jaw skeleton - + - + cjm @@ -352915,7 +352905,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -352950,14 +352940,14 @@ https://doi.org/10.1515/9783110264043 lower jaw region http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png - + - + Wikipedia:Mandibular_prominence @@ -353145,7 +353135,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -353170,14 +353160,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001731 cavity of pharynx - + - + XAO @@ -353456,7 +353446,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -353499,14 +353489,14 @@ https://doi.org/10.1515/9783110264043 iris - + - + XAO @@ -353585,7 +353575,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -353637,14 +353627,14 @@ https://doi.org/10.1515/9783110264043 corneal epithelium http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + ISBN:0781772214 @@ -353741,15 +353731,15 @@ https://doi.org/10.1515/9783110264043 - - + + - + @@ -353791,34 +353781,34 @@ https://doi.org/10.1515/9783110264043 sclera http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + FMA - + ZFA - + ISBN:0781772214 @@ -353869,7 +353859,7 @@ https://doi.org/10.1515/9783110264043 - + A skeletal muscle organ that is part of the trunk region. Note that this class excludes smooth muscle elements in the trunk region, such as the internal anal sphincter. This appears to be consistent with other ontologies such as FMA and ZFA which appear to only include skeletal muscles here. In fact the MA class 'trunk muscle' is classified as a 'set of skeletal muscles'. Many ontologies do not appear to have a coherent distinction between an individual muscle and the musculature (i.e. the set of muscles in a region), so we group all together here. @@ -353894,14 +353884,14 @@ https://doi.org/10.1515/9783110264043 skeletal muscle of trunk - + - + prolog @@ -353972,7 +353962,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -354011,14 +354001,14 @@ https://doi.org/10.1515/9783110264043 ciliary body http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + ISBN:0781772214 @@ -354066,14 +354056,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -354136,24 +354126,24 @@ https://doi.org/10.1515/9783110264043 optic choroid http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + MA - + Wikipedia @@ -354254,7 +354244,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -354303,14 +354293,14 @@ https://doi.org/10.1515/9783110264043 substantia propria of cornea http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + cjm ISBN:0781772214 Wikipedia @@ -354378,15 +354368,15 @@ https://doi.org/10.1515/9783110264043 - + - - - + + + A double layer covering the ciliary body that produces aqueous humor. BTO:0001770 @@ -354406,15 +354396,15 @@ https://doi.org/10.1515/9783110264043 ciliary epithelium - + - + - + @@ -354427,19 +354417,19 @@ https://doi.org/10.1515/9783110264043 - + MA - + MP - + Wikipedia @@ -354874,7 +354864,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -354910,14 +354900,14 @@ https://doi.org/10.1515/9783110264043 aqueous humor of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + FMA def states A and P located_in in EHDAA2 VHOG @@ -355047,8 +355037,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -355081,24 +355071,24 @@ https://doi.org/10.1515/9783110264043 anterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png - + - + - + FMA - + cjm @@ -355150,8 +355140,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -355181,24 +355171,24 @@ https://doi.org/10.1515/9783110264043 posterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + FMA - + cjm @@ -355386,7 +355376,7 @@ https://doi.org/10.1515/9783110264043 - + The elastic, clear, membrane-like structure, that is outer most layer of the lens. The transparent membrane which surrounds the lens of the eye. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG] (...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod. (...) A watery aqueous humor fills the spaces in the eye in front of the lens (...) (reference 2).[well established][VHOG] @@ -355412,14 +355402,14 @@ https://doi.org/10.1515/9783110264043 capsule of lens http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png - + - + EHDAA2 @@ -355595,7 +355585,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -355634,14 +355624,14 @@ https://doi.org/10.1515/9783110264043 sympathetic ganglion http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png - + - + DOI:10.1101/gr.157586.113 ISBN:0073040584 @@ -355705,7 +355695,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -355716,7 +355706,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -355759,11 +355749,11 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/9/90/Lips.JPG http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg - + - + @@ -355776,7 +355766,7 @@ https://doi.org/10.1515/9783110264043 - + BTO FMA-implicit VHOG @@ -355785,7 +355775,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -356169,14 +356159,14 @@ https://doi.org/10.1515/9783110264043 - + - + The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. developmental relationships need revised @@ -356229,24 +356219,24 @@ https://doi.org/10.1515/9783110264043 midbrain http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG - + - + - + definitional - + Bgee:AN @@ -356467,7 +356457,7 @@ https://doi.org/10.1515/9783110264043 - + Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]. Anterior part of the hindbrain ventral to the cerebellum[BIRNLEX:965]. @@ -356503,14 +356493,14 @@ https://doi.org/10.1515/9783110264043 metencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -356772,7 +356762,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of a small intestine [Automatically generated definition]. Intestinal epithelium which lines the lumen of the mid intestine.[TAO] BTO:0001258 @@ -356797,14 +356787,14 @@ https://doi.org/10.1515/9783110264043 epithelium of small intestine - + - + FMA @@ -357202,7 +357192,7 @@ https://doi.org/10.1515/9783110264043 - + Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. Together, our results reveal a shared basic organization in the tegmental domains of the diencephalon and midbrain of developing lamprey, indicating early appearance of the domain in vertebrate phylogeny.[well established][VHOG] @@ -357243,14 +357233,14 @@ https://doi.org/10.1515/9783110264043 midbrain tegmentum http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png - + - + ZFA @@ -357562,7 +357552,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -357621,14 +357611,14 @@ https://doi.org/10.1515/9783110264043 bile - + - + 0.3% in humans @@ -357839,7 +357829,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a esophagus [Automatically generated definition]. EMAPA:26987 FMA:63050 @@ -357868,14 +357858,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0001974 lamina propria of esophagus - + - + FMA @@ -358107,7 +358097,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -358148,14 +358138,14 @@ https://doi.org/10.1515/9783110264043 epithelium of esophagus - + - + FMA @@ -358469,8 +358459,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -358483,7 +358473,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -358542,34 +358532,34 @@ https://doi.org/10.1515/9783110264043 blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -358936,10 +358926,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. Phylogenetic analyses of the concatenated data set using maximum parsimony, maximum likelihood and distance based (neighbour joining) methods all converged on a nearly identical, well supported topology defining four principal eutherian lineages. The results affirm monophyly of traditional placental orders (except Artiodactyla and Insectivora), and also support some previously proposed, as well as new, superordinal clades.[well established][VHOG] @@ -358976,44 +358966,44 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/f/f1/Placenta.svg https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb - + - + - + - + - + https://github.com/obophenotype/uberon/issues/1376 - + ISBN:0073040584 - + Wikipedia - + ISBN:0073040584 @@ -359238,9 +359228,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.. @@ -359282,35 +359272,35 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png - + - + - + - + Wikipedia - + EHDAA2 XAO - + EHDAA2 @@ -359809,7 +359799,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -359828,7 +359818,7 @@ https://doi.org/10.1515/9783110264043 - + The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. @@ -359879,25 +359869,25 @@ https://doi.org/10.1515/9783110264043 hindbrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + - + modified-source-relation ABA - + Bgee:AN @@ -360268,7 +360258,7 @@ https://doi.org/10.1515/9783110264043 - + The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]. @@ -360299,14 +360289,14 @@ https://doi.org/10.1515/9783110264043 pontine raphe nucleus - + - + Wikipedia @@ -360390,7 +360380,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -360493,14 +360483,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb - + - + some species only have a single lung @@ -360819,9 +360809,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles. assume spelling error for ncit EHDAA2:0004143 @@ -360839,15 +360829,15 @@ https://doi.org/10.1515/9783110264043 truncus arteriosus - + - + - + @@ -360866,19 +360856,19 @@ https://doi.org/10.1515/9783110264043 - + MA - + EHDAA2 - + EHDAA2 @@ -360909,7 +360899,7 @@ https://doi.org/10.1515/9783110264043 - + The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves.[TAO] relationship loss: develops_from endocardial ring (TAO:0005072)[TAO] @@ -360941,14 +360931,14 @@ https://doi.org/10.1515/9783110264043 endocardial cushion http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png - + - + ZFA @@ -361031,14 +361021,14 @@ https://doi.org/10.1515/9783110264043 - + - + The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart. Heart region collecting blood from the paired common cardinal veins and delivering to the atrium. One of four components of the heart. The sinus venosus also acts as a pacemaker and is the first to contract. Kimmel et al, 1995.[TAO] Part of the circulatory system which receives blood from the systemic veins and contracts to pump the blood into the atrium of the heart.[AAO] @@ -361073,24 +361063,24 @@ https://doi.org/10.1515/9783110264043 sinus venosus http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png - + - + - + VHOG - + Bgee:AN @@ -361193,7 +361183,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -361230,7 +361220,7 @@ https://doi.org/10.1515/9783110264043 - + The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. Consider adding a layer-of-skin grouping class for all skin layers @@ -361270,24 +361260,24 @@ https://doi.org/10.1515/9783110264043 dermis http://upload.wikimedia.org/wikipedia/commons/2/23/EpidermisPainted.svg - + - + - + FMA - + definitional @@ -361345,7 +361335,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -361364,7 +361354,7 @@ https://doi.org/10.1515/9783110264043 - + Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO] @@ -361400,24 +361390,24 @@ https://doi.org/10.1515/9783110264043 hypodermis http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg - + - + - + ZFA - + FMA-modified @@ -361867,8 +361857,8 @@ https://doi.org/10.1515/9783110264043 - - + + A cardiac ventricle that is in the right side of the heart. The muscular chamber on the right and in front of the left ventricle. It generally receives venous blood from the right atrium and conveys it into the pulmonary artery. [(1988)_Dorian_AF, Amsterdam, Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B._Anatomy, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier's_Encyclopaedic_Dictionary_of_Medicine][VHOG] @@ -361901,24 +361891,24 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + - + PMID:17276708 - + cjm @@ -362109,7 +362099,7 @@ https://doi.org/10.1515/9783110264043 - + Cardiac chamber through which blood leaves the heart. A chamber of the heart that receives blood from one or more atria and pumps it by muscular contraction into the arteries.[AAO] One of four heart chambers.[TAO] @@ -362148,14 +362138,14 @@ https://doi.org/10.1515/9783110264043 cardiac ventricle - + - + Bgee:AN @@ -362236,7 +362226,7 @@ https://doi.org/10.1515/9783110264043 - + A cardiac ventricle that is in the left side of the heart. Thick-walled muscular chamber constituting the left border and apex of the heart. It receives oxygenated blood from the left atrium through the mitral orifice and send it off into the aorta. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG] @@ -362270,14 +362260,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + GO @@ -362922,7 +362912,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -362968,14 +362958,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Skin.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.3/3d-vh-f-skin.glb - + - + Wikipathways:WP2062 @@ -363324,7 +363314,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -363376,14 +363366,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spleen.glb https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg - + - + multiple sources - true spleen appear in jawed vertebrates @@ -363441,22 +363431,22 @@ https://doi.org/10.1515/9783110264043 - + - + - - + + @@ -363536,19 +363526,19 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Liver.glb https://upload.wikimedia.org/wikipedia/commons/6/64/Leber_Schaf.jpg - + - + - + - + @@ -363563,25 +363553,25 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + ZFA-weakened - + EHDAA2 - + http://www.stembook.org/node/512 @@ -363813,7 +363803,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -363884,7 +363874,7 @@ https://doi.org/10.1515/9783110264043 https://upload.wikimedia.org/wikipedia/commons/b/b1/GallbladderAnatomy-en.svg https://upload.wikimedia.org/wikipedia/commons/f/f4/Abdomal_organs.svg - + @@ -363897,7 +363887,7 @@ https://doi.org/10.1515/9783110264043 - + definitional @@ -364264,7 +364254,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -364277,7 +364267,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -364328,24 +364318,24 @@ https://doi.org/10.1515/9783110264043 kidney - + - + - + FMA - + definitional @@ -364654,8 +364644,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -364699,11 +364689,11 @@ https://doi.org/10.1515/9783110264043 Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 pronephros - + - + @@ -364716,13 +364706,13 @@ https://doi.org/10.1515/9783110264043 - + OG - + ZFA @@ -364815,7 +364805,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -364854,14 +364844,14 @@ https://doi.org/10.1515/9783110264043 superior olivary complex http://upload.wikimedia.org/wikipedia/commons/4/46/Gray713.png - + - + NIFSTD @@ -364960,7 +364950,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -365018,14 +365008,14 @@ https://doi.org/10.1515/9783110264043 locus ceruleus http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png - + - + check ZFA NIFSTD @@ -365159,7 +365149,7 @@ https://doi.org/10.1515/9783110264043 - + Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703). @@ -365195,14 +365185,14 @@ https://doi.org/10.1515/9783110264043 superior salivatory nucleus http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray788.png - + - + definitional @@ -365337,7 +365327,7 @@ https://doi.org/10.1515/9783110264043 - + The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]. Layer that lines the lumen of the heart.[TAO] Part of the heart comprised of thin serous membrane, composed of endothelial tissue, that lines the interior of the heart.[AAO] @@ -365379,14 +365369,14 @@ https://doi.org/10.1515/9783110264043 endocardium http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png - + - + Bgee:AN @@ -365867,7 +365857,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -365927,7 +365917,7 @@ https://doi.org/10.1515/9783110264043 integument - + @@ -365940,7 +365930,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -366207,7 +366197,7 @@ https://doi.org/10.1515/9783110264043 - + Vasculature that is part of the eye region. not part of the eye in ZFA. Note this changed to a blood vessel in ZFA @@ -366230,14 +366220,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + ISBN:0781772214 @@ -366296,7 +366286,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -366337,14 +366327,14 @@ https://doi.org/10.1515/9783110264043 musculoskeletal system - + - + check ctenophore @@ -366634,7 +366624,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -366647,8 +366637,8 @@ https://doi.org/10.1515/9783110264043 - - + + Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). TODO - add superclass to unify with VNC? @@ -366707,34 +366697,34 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spinal_Cord.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spinal_Cord.glb - + - + - + - + ZFA - + definitional - + definitional @@ -366926,7 +366916,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -366977,14 +366967,14 @@ https://doi.org/10.1515/9783110264043 ventral horn of spinal cord - + - + FMA-abduced-lr @@ -367283,7 +367273,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -367313,14 +367303,14 @@ https://doi.org/10.1515/9783110264043 dorsal mesentery http://upload.wikimedia.org/wikipedia/commons/8/85/Gray985.png - + - + EHDAA2 @@ -367799,7 +367789,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -367840,14 +367830,14 @@ https://doi.org/10.1515/9783110264043 EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct coelemic cavity lumen - + - + definitional @@ -367953,7 +367943,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a back [Automatically generated definition]. EMAPA:35161 @@ -367967,14 +367957,14 @@ https://doi.org/10.1515/9783110264043 muscle of back - + - + prolog @@ -368190,9 +368180,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -368249,15 +368239,15 @@ https://doi.org/10.1515/9783110264043 notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -368276,19 +368266,19 @@ https://doi.org/10.1515/9783110264043 - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -368373,7 +368363,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -368384,7 +368374,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -368436,11 +368426,11 @@ https://doi.org/10.1515/9783110264043 somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -368453,13 +368443,13 @@ https://doi.org/10.1515/9783110264043 - + GOTAX:0000352 - + ZFA @@ -368904,12 +368894,12 @@ https://doi.org/10.1515/9783110264043 - - - - - - + + + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -368949,66 +368939,66 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -369381,15 +369371,15 @@ https://doi.org/10.1515/9783110264043 - - + + - + A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart. External layer of the heart.[TAO] @@ -369419,34 +369409,34 @@ https://doi.org/10.1515/9783110264043 EDITOR_NOTE TODO - check links with UBERON:0002425 visceral serous pericardium. develops from proepicardium. WP:Epicardium -- When considered as a part of the pericardium, it is the inner layer, or visceral pericardium, continuous with the serous layer. epicardium - + - + - + - + multiple - + FMA-inferred - + FMA @@ -369633,11 +369623,11 @@ https://doi.org/10.1515/9783110264043 - - - - - + + + + + @@ -369674,23 +369664,23 @@ https://doi.org/10.1515/9783110264043 conducting system of heart - + - + - + - + - + @@ -369703,31 +369693,31 @@ https://doi.org/10.1515/9783110264043 - + FMA - + FMA - + FMA - + FMA - + FMA @@ -369794,7 +369784,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -369858,7 +369848,7 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/d/d2/Sinoatrial_node_low_mag.jpg http://upload.wikimedia.org/wikipedia/commons/d/de/Sinoatrial_node_2_low_mag.jpg - + @@ -369871,7 +369861,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -370154,8 +370144,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -370185,11 +370175,11 @@ https://doi.org/10.1515/9783110264043 cardiac Purkinje fiber http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png - + - + @@ -370202,7 +370192,7 @@ https://doi.org/10.1515/9783110264043 - + https://github.com/obophenotype/uberon/issues/1785 https://orcid.org/0000-0001-5208-3432 https://orcid.org/0000-0002-9791-0064 @@ -370210,7 +370200,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -370357,7 +370347,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -370370,7 +370360,7 @@ https://doi.org/10.1515/9783110264043 - + Serous membrane which is divided into parietal and visceral serous pericardium. EMAPA:19030 FMA:9582 @@ -370384,24 +370374,24 @@ https://doi.org/10.1515/9783110264043 serous pericardium - + - + - + FMA - + FMA @@ -370442,7 +370432,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -370480,14 +370470,14 @@ https://doi.org/10.1515/9783110264043 peritoneum http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png - + - + MP @@ -370540,14 +370530,14 @@ https://doi.org/10.1515/9783110264043 - + - + Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]. most superficial part of pericardium; continuous with the outer adventitial layer of the neighboring great blood vessels. [Wikipedia:Pericardium] EMAPA:19029 @@ -370563,11 +370553,11 @@ https://doi.org/10.1515/9783110264043 fibrous pericardium - + - + @@ -370580,13 +370570,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + WP @@ -370798,7 +370788,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -370856,14 +370846,14 @@ https://doi.org/10.1515/9783110264043 bone marrow http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg - + - + FMA MA @@ -370935,8 +370925,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -370975,24 +370965,24 @@ https://doi.org/10.1515/9783110264043 defined generically so could in theory encompass FBbt:00003260 'skeletal muscle of head', or the muscle of a starfish Aristotle's lantern, but we restrict this to craniates. Skeletal muscles of the head originate from the non-segmented head mesoderm (Noden, 1983; Wachtler et al., 1984) cranial muscle - + - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships - + EHDAA2-abduced @@ -371067,7 +371057,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle that is part of the cervical (neck) region. EMAPA:36050 @@ -371089,14 +371079,14 @@ https://doi.org/10.1515/9783110264043 muscle of neck - + - + prolog @@ -371154,7 +371144,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -371186,14 +371176,14 @@ https://doi.org/10.1515/9783110264043 muscle of abdomen - + - + prolog @@ -371451,14 +371441,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -371507,24 +371497,24 @@ https://doi.org/10.1515/9783110264043 hematopoietic system - + - + - + FMA - + definitional @@ -371580,15 +371570,15 @@ https://doi.org/10.1515/9783110264043 - + + - @@ -371635,25 +371625,25 @@ https://doi.org/10.1515/9783110264043 bile duct http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png - + - + - + EMAPA MA - + XAO @@ -371971,7 +371961,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -372016,14 +372006,14 @@ https://doi.org/10.1515/9783110264043 visceral pleura - + - + FMA @@ -372103,7 +372093,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -372149,14 +372139,14 @@ https://doi.org/10.1515/9783110264043 pleural cavity http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png - + - + Wikipedia @@ -372327,7 +372317,7 @@ https://doi.org/10.1515/9783110264043 - + A double-walled sac containing the heart and the roots of the great vessels. FMA:9868 RETIRED_EHDAA2:0001443 @@ -372341,14 +372331,14 @@ https://doi.org/10.1515/9783110264043 pericardial sac http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png - + - + FMA @@ -372372,7 +372362,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -372431,14 +372421,14 @@ https://doi.org/10.1515/9783110264043 pericardium http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png - + - + MA @@ -372631,7 +372621,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -372687,7 +372677,7 @@ https://doi.org/10.1515/9783110264043 autonomic nervous system http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png - + @@ -372700,7 +372690,7 @@ https://doi.org/10.1515/9783110264043 - + EMAPA MA NIFSTD @@ -372818,9 +372808,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -372851,15 +372841,15 @@ https://doi.org/10.1515/9783110264043 clitoris http://upload.wikimedia.org/wikipedia/commons/c/cf/Clitoris_anatomy_labeled-en.svg - + - + - + @@ -372872,19 +372862,19 @@ https://doi.org/10.1515/9783110264043 - + MA - + Wikipedia - + EHDAA2 Wikipedia @@ -373758,7 +373748,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues. consider including separate class for developmental structure (adult human is stratified; in EHDAA2 is unilaminar) The epithelium that lines the oral cavity. The oral epithelium epithelial cells with many short microvilli as well as mucous cells, rodlet cells and taste buds[ZFIN:ZDB-PUB-060921-12, ZFIN:ZDB-PUB-091204-24]. @@ -373785,14 +373775,14 @@ https://doi.org/10.1515/9783110264043 oral epithelium - + - + AAO-modified @@ -373855,8 +373845,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -373884,24 +373874,24 @@ https://doi.org/10.1515/9783110264043 visceral serous pericardium - + - + - + cjm - + FMA @@ -374057,7 +374047,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -374103,7 +374093,7 @@ https://doi.org/10.1515/9783110264043 decidua http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray33.png - + @@ -374116,7 +374106,7 @@ https://doi.org/10.1515/9783110264043 - + maternal MA @@ -374203,7 +374193,7 @@ https://doi.org/10.1515/9783110264043 - + The mucous secreting gland associated with the mucuous membrane lining the uterus. simple or branched tubular @@ -374231,7 +374221,7 @@ https://doi.org/10.1515/9783110264043 endometrial gland http://upload.wikimedia.org/wikipedia/commons/2/28/Gray1169.png - + @@ -374244,7 +374234,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia:Tubular_gland @@ -374822,14 +374812,14 @@ https://doi.org/10.1515/9783110264043 - + - - + + @@ -374855,11 +374845,11 @@ https://doi.org/10.1515/9783110264043 iris epithelium - + - + @@ -374872,13 +374862,13 @@ https://doi.org/10.1515/9783110264043 - + MA - + MP @@ -374945,7 +374935,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -374973,14 +374963,14 @@ https://doi.org/10.1515/9783110264043 trabecula carnea - + - + WP @@ -375065,7 +375055,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -375099,7 +375089,7 @@ https://doi.org/10.1515/9783110264043 https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg - + @@ -375112,7 +375102,7 @@ https://doi.org/10.1515/9783110264043 - + VSAO @@ -375384,8 +375374,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -375411,11 +375401,11 @@ https://doi.org/10.1515/9783110264043 tunica media https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg - + - + @@ -375428,13 +375418,13 @@ https://doi.org/10.1515/9783110264043 - + cjm - + cjm @@ -375471,8 +375461,8 @@ https://doi.org/10.1515/9783110264043 - - + + The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]. the FMA class represents a more generic layer which is the superclass of the layer found in both blood vessels and lymph vessels (and also endocardium) - we should probably follow this structure the FMA class represents a structure which may have both epithelium and fibroelastic connective tissue as parts @@ -375497,11 +375487,11 @@ https://doi.org/10.1515/9783110264043 tunica intima https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg - + - + @@ -375514,13 +375504,13 @@ https://doi.org/10.1515/9783110264043 - + check for exceptions, e.g. capillaries - + ISBN:0073040584 @@ -375990,9 +375980,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO] A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down.[well established][VHOG] @@ -376028,15 +376018,15 @@ https://doi.org/10.1515/9783110264043 pharyngeal arch http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray41.png - + - + - + @@ -376049,19 +376039,19 @@ https://doi.org/10.1515/9783110264043 - + PMID:16313389 - + http://tolweb.org/Chordata/2499 - + PMID:16313389 @@ -376130,7 +376120,7 @@ https://doi.org/10.1515/9783110264043 - + Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. Do not merge with neurogenic placode Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons @@ -376150,7 +376140,7 @@ https://doi.org/10.1515/9783110264043 cranial placode - + @@ -376163,7 +376153,7 @@ https://doi.org/10.1515/9783110264043 - + PMID:11523831 PMID:22512454 @@ -377158,7 +377148,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -377177,7 +377167,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. consider adding class for organizer. Consider adding separate class for isthmus as a structure Lampreys also have an MHB [midbrain hindbrain boundary], expressing a similar repertoire of regulatory gene cognates as in gnathostomes.[well established][VHOG] @@ -377207,11 +377197,11 @@ https://doi.org/10.1515/9783110264043 midbrain-hindbrain boundary - + - + @@ -377225,13 +377215,13 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + ZFA @@ -377277,8 +377267,8 @@ https://doi.org/10.1515/9783110264043 - - + + A temporary epithelium that derives from the outer layer of the ectdoerm and is shed once the inner layer differentiates to form a true epidermis. The outermost epidermal layer covering the fish at embryonic stages; derived from the EVL and thought to eventually be replaced by the superficial stratum of the epidermis. Sometimes used synonymously with EVL. Le Guellec et al, 2004.[TAO] relationship type change: OBO_REL:part_of ectoderm (TAO:0000016) CHANGED TO: develops_from ectoderm (UBERON:0000924)[TAO] @@ -377307,11 +377297,11 @@ https://doi.org/10.1515/9783110264043 periderm - + - + @@ -377324,13 +377314,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + ZFA @@ -377496,7 +377486,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -377519,7 +377509,7 @@ https://doi.org/10.1515/9783110264043 - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -377544,14 +377534,14 @@ https://doi.org/10.1515/9783110264043 presomitic mesoderm - + - + Bgee:AN @@ -377611,8 +377601,8 @@ https://doi.org/10.1515/9783110264043 - - + + In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. Duct of the embryonic kidney, present bilaterally ventral to the somites and leading to the anal region where it empties separately from, and just posterior to the anus. Kimmel et al, 1995.[TAO] The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG] @@ -377636,11 +377626,11 @@ https://doi.org/10.1515/9783110264043 The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] pronephric duct - + - + @@ -377653,13 +377643,13 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia - + XAO @@ -377848,14 +377838,14 @@ https://doi.org/10.1515/9783110264043 - + - + A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue. TODO - check; developmental relationship to anterior hypoblast in ZFA? Axial hypoblast located anterior to the chorda mesoderm; the polster is its most anterior region. Kimmel et al, 1995.[TAO] @@ -377880,24 +377870,24 @@ https://doi.org/10.1515/9783110264043 prechordal plate - + - + - + ZFA - + PMID:16313393 @@ -377954,9 +377944,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -377998,34 +377988,34 @@ https://doi.org/10.1515/9783110264043 intermediate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + - + AAO - + EMAPA - + XAO @@ -378337,7 +378327,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -378375,7 +378365,7 @@ https://doi.org/10.1515/9783110264043 eye primordium - + @@ -378388,7 +378378,7 @@ https://doi.org/10.1515/9783110264043 - + PMID:16496288 XAO @@ -378450,8 +378440,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -378480,24 +378470,24 @@ https://doi.org/10.1515/9783110264043 optic cup - + - + - + ZFA - + ZFA @@ -378563,7 +378553,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -378604,7 +378594,7 @@ https://doi.org/10.1515/9783110264043 lens placode http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png - + @@ -378617,7 +378607,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -378686,7 +378676,7 @@ https://doi.org/10.1515/9783110264043 - + Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. Consider adding subclasses for male and female specific variants TODO - mesonephric portion of the nephric duct @@ -378724,7 +378714,7 @@ https://doi.org/10.1515/9783110264043 mesonephric duct http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + @@ -378737,7 +378727,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -378827,15 +378817,15 @@ https://doi.org/10.1515/9783110264043 - + - - + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -378867,34 +378857,34 @@ https://doi.org/10.1515/9783110264043 neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -379019,7 +379009,7 @@ https://doi.org/10.1515/9783110264043 - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -379048,7 +379038,7 @@ https://doi.org/10.1515/9783110264043 paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -379061,7 +379051,7 @@ https://doi.org/10.1515/9783110264043 - + Bgee:AN @@ -379130,8 +379120,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -379157,11 +379147,11 @@ https://doi.org/10.1515/9783110264043 epibranchial placode - + - + @@ -379175,13 +379165,13 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + EHDAA2-abduced @@ -379284,7 +379274,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -379328,7 +379318,7 @@ https://doi.org/10.1515/9783110264043 lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -379341,7 +379331,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 VHOG @@ -379425,7 +379415,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -379468,7 +379458,7 @@ https://doi.org/10.1515/9783110264043 myotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + @@ -379481,7 +379471,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2-abduced @@ -379544,7 +379534,7 @@ https://doi.org/10.1515/9783110264043 - + Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]. Post-cranial portion of the neural crest. Exact anatomical derivations not experimentally resolved in amphibians.[AAO] We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG] @@ -379564,14 +379554,14 @@ https://doi.org/10.1515/9783110264043 trunk neural crest - + - + ZFA @@ -379614,15 +379604,15 @@ https://doi.org/10.1515/9783110264043 - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO] @@ -379642,15 +379632,15 @@ https://doi.org/10.1515/9783110264043 heart primordium - + - + - + @@ -379663,19 +379653,19 @@ https://doi.org/10.1515/9783110264043 - + ZFA - + ZFA - + XAO @@ -379813,8 +379803,8 @@ https://doi.org/10.1515/9783110264043 - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. Skeletogenic portion of somites.[AAO] The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] @@ -379842,11 +379832,11 @@ https://doi.org/10.1515/9783110264043 sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -379865,13 +379855,13 @@ https://doi.org/10.1515/9783110264043 - + VHOG:0000680 - + ZFA @@ -381200,8 +381190,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -381249,24 +381239,24 @@ https://doi.org/10.1515/9783110264043 chorion membrane http://upload.wikimedia.org/wikipedia/commons/5/51/Gray24.png - + - + - + Hymans - + ISBN:0073040584 @@ -381889,7 +381879,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -381917,14 +381907,14 @@ https://doi.org/10.1515/9783110264043 Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] metanephric mesenchyme - + - + ISBN:9780878932504 @@ -381988,14 +381978,14 @@ https://doi.org/10.1515/9783110264043 - - + + - - + + An extraembryonic structure that develops_from a syncytiotrophoblast and is part of a chorion. TODO - check EHDAA2:0001973 @@ -382004,24 +381994,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0003224 chorion syncytiotrophoblast - + - + - + EHDAA2 - + polar trophectoderm syncytiotrophoblast EHDAA2 @@ -382427,7 +382417,7 @@ https://doi.org/10.1515/9783110264043 - + A mesenchyme that is part of a chorion. TODO - check UBERON:0003423 @@ -382446,7 +382436,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0003265 chorionic mesenchyme - + @@ -382465,7 +382455,7 @@ https://doi.org/10.1515/9783110264043 - + ISBN:0073040584 @@ -382673,8 +382663,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -382706,24 +382696,24 @@ https://doi.org/10.1515/9783110264043 skeleton of lower jaw - + - + - + EHDAA2 - + VHOG-modified @@ -382799,12 +382789,12 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -382831,7 +382821,7 @@ https://doi.org/10.1515/9783110264043 mesentery of stomach - + @@ -382844,7 +382834,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -383156,13 +383146,13 @@ https://doi.org/10.1515/9783110264043 - + - + Racemose mucous glands beneath the mucous membrane of the pharynx. BTO:0004849 EHDAA2:0001461 @@ -383175,14 +383165,14 @@ https://doi.org/10.1515/9783110264043 pharyngeal gland - + - + BTO @@ -383291,7 +383281,7 @@ https://doi.org/10.1515/9783110264043 - + A blood island that is part of a mesoderm. in EHDAA2, gives rise to blood and dorsal aorta UBERON:0003305 @@ -383304,7 +383294,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0003304 mesoderm blood island - + @@ -383317,7 +383307,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -383416,7 +383406,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a developing camera-type eye. TODO - change mesenchyme relationships to precursor_of EHDAA2:0000485 @@ -383428,14 +383418,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003314 eye mesenchyme - + - + EHDAA2 @@ -383628,7 +383618,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a developing upper jaw [Automatically generated definition]. EHDAA2:0002124 EHDAA:8031 @@ -383641,14 +383631,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003323 mesenchyme of upper jaw - + - + EHDAA2 @@ -383699,7 +383689,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a developing lower jaw [Automatically generated definition]. EHDAA2:0001024 EHDAA:8003 @@ -383712,14 +383702,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003324 mesenchyme of lower jaw - + - + EHDAA2 @@ -385111,15 +385101,15 @@ https://doi.org/10.1515/9783110264043 - + + - An epithelium that is part of a pharynx [Automatically generated definition]. Epithelium lining the pharynx consisting largely of simple columnar epithelium with a short segment (1mm) of stratified squamous epithelium on the ventral side. Chen et al, 2007.[TAO] BSA:0000112 @@ -385139,24 +385129,24 @@ https://doi.org/10.1515/9783110264043 pharyngeal epithelium - + - + - + ZFA - + ZFA @@ -385208,12 +385198,12 @@ https://doi.org/10.1515/9783110264043 - + - + An epithelium that is part of a midgut. BTO:0005053 EHDAA2:0001195 @@ -385226,14 +385216,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003352 epithelium of midgut - + - + BTO @@ -385526,7 +385516,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -385539,7 +385529,7 @@ https://doi.org/10.1515/9783110264043 - + An unilaminar epithelium that surrounds a pelvic appendage bud. UBERON:0005232 EHDAA2:0001034 @@ -385555,24 +385545,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0003371 pelvic appendage bud ectoderm - + - + - + EHDAA2 - + EHDAA2 @@ -385640,7 +385630,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -385653,7 +385643,7 @@ https://doi.org/10.1515/9783110264043 - + An unilaminar epithelium that surrounds a pectoral appendage bud. UBERON:0005231 UBERON:0005663 @@ -385670,24 +385660,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0003372 pectoral appendage bud ectoderm - + - + - + EHDAA2 - + EHDAA2 @@ -385751,7 +385741,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -385762,7 +385752,7 @@ https://doi.org/10.1515/9783110264043 - + An extraembryonic structure that develops_from a ectoderm and is part of a chorion. BTO:0005145 EMAPA:16113 @@ -385773,14 +385763,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003374 chorionic ectoderm - + - + ISBN:0073040584 @@ -387229,7 +387219,7 @@ https://doi.org/10.1515/9783110264043 - + A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP]. TODO - check @@ -387244,14 +387234,14 @@ https://doi.org/10.1515/9783110264043 mesenchyme of umbilical cord - + - + Wikipedia @@ -388260,13 +388250,13 @@ https://doi.org/10.1515/9783110264043 - + - + A bone that is part of a facial skeleton [Automatically generated definition]. test whether 'facial bone' is an exact synonym EMAPA:19019 @@ -388287,14 +388277,14 @@ https://doi.org/10.1515/9783110264043 facial bone - + - + MA @@ -388447,14 +388437,14 @@ https://doi.org/10.1515/9783110264043 - + - + The ureteral branches of renal artery are small branches which supply the ureter. ureteric artery @@ -388468,24 +388458,24 @@ https://doi.org/10.1515/9783110264043 ureteric segment of renal artery - + - + - + FMA - + FMA @@ -388569,7 +388559,7 @@ https://doi.org/10.1515/9783110264043 - + The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose. EMAPA:37430 @@ -388586,14 +388576,14 @@ https://doi.org/10.1515/9783110264043 artery of upper lip - + - + FMA @@ -388659,7 +388649,7 @@ https://doi.org/10.1515/9783110264043 - + The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery. EMAPA:37429 @@ -388677,14 +388667,14 @@ https://doi.org/10.1515/9783110264043 artery of lower lip - + - + FMA @@ -389310,7 +389300,7 @@ https://doi.org/10.1515/9783110264043 - + An endothelium of capillary that is part of a respiratory system [Automatically generated definition]. EMAPA:37575 MA:0001808 @@ -389341,14 +389331,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003489 respiratory system capillary endothelium - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -389580,7 +389570,7 @@ https://doi.org/10.1515/9783110264043 - + An arteriole that is part of a respiratory system [Automatically generated definition]. EMAPA:37568 MA:0001803 @@ -389588,14 +389578,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003495 respiratory system arteriole - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -389629,7 +389619,7 @@ https://doi.org/10.1515/9783110264043 - + A blood vessel that is part of a head [Automatically generated definition]. EMAPA:36610 MA:0000575 @@ -389641,14 +389631,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003496 head blood vessel - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -393869,12 +393859,12 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -393901,7 +393891,7 @@ https://doi.org/10.1515/9783110264043 intrahepatic bile duct - + @@ -393914,7 +393904,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -394477,7 +394467,7 @@ https://doi.org/10.1515/9783110264043 - + The central part of the thoracic cavity enclosed by the left and right pleurae. mediastinal CALOHA:TS-2338 @@ -394499,14 +394489,14 @@ https://doi.org/10.1515/9783110264043 mediastinum http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png - + - + FMA @@ -395026,7 +395016,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a thorax [Automatically generated definition]. MA:0000561 muscle organ of thorax @@ -395036,14 +395026,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003830 thoracic segment muscle - + - + prolog @@ -395155,7 +395145,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a esophagus [Automatically generated definition]. merge muscle and muscle layer? EMAPA:26983 @@ -395172,14 +395162,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003832 esophagus muscle - + - + MA @@ -396044,12 +396034,12 @@ https://doi.org/10.1515/9783110264043 - + - + A neural plate that develops_from a future spinal cord. Neural plate that is part of the spinal cord. [Bgee_curator][VHOG] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...)[well established][VHOG] @@ -396062,14 +396052,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003854 spinal cord neural plate - + - + ZFA @@ -396322,7 +396312,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -396338,14 +396328,14 @@ https://doi.org/10.1515/9783110264043 intraembryonic coelom - + - + Wikipedia @@ -396413,7 +396403,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -396472,14 +396462,14 @@ https://doi.org/10.1515/9783110264043 fallopian tube http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg - + - + FMA-abduced-lr @@ -396554,7 +396544,7 @@ https://doi.org/10.1515/9783110264043 - + Paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]. Either of the paired embryonic ducts developing into the uterine tubes, uterus, and vagina in the female and becoming largely obliterated in the male. [TFD][VHOG] Transient developmental organ which gives rise to oviducts in female (documented to persist in some male frogs).[AAO] @@ -396584,14 +396574,14 @@ https://doi.org/10.1515/9783110264043 Mullerian duct http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + - + Wikipedia @@ -396713,8 +396703,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -396748,11 +396738,11 @@ https://doi.org/10.1515/9783110264043 liver primordium - + - + @@ -396771,13 +396761,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + ventral foregut endoderm Zaret 1996 @@ -396900,7 +396890,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -396920,14 +396910,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0003898 skeletal muscle tissue of trunk - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -396988,7 +396978,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -397011,7 +397001,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the retina that contains neurons and photoreceptor cells[GO]. (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG] @@ -397043,14 +397033,14 @@ https://doi.org/10.1515/9783110264043 retinal neural layer - + - + Bgee:AN @@ -397370,7 +397360,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -397400,14 +397390,14 @@ https://doi.org/10.1515/9783110264043 pancreas primordium http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png - + - + Wikipedia @@ -397449,16 +397439,16 @@ https://doi.org/10.1515/9783110264043 - - + + - - + + The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]. EFO:0003470 EMAPA:35645 @@ -397479,19 +397469,19 @@ https://doi.org/10.1515/9783110264043 http://upload.wikimedia.org/wikipedia/commons/4/49/Suckale08FBS_fig1_pancreas_development.jpeg http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png - + - + - + - + @@ -397504,26 +397494,26 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + Wikipedia:Pancreas#Embryological_development - + zebrafish Wikipedia:Pancreatic_bud - + EHDAA2-inferred @@ -397565,8 +397555,8 @@ https://doi.org/10.1515/9783110264043 - - + + Pancreatic bud that gives rise to the accessory pancreatic duct. The pancreatic bud that gives rise to the accessory pancreatic duct.[AAO] In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG] @@ -397594,24 +397584,24 @@ https://doi.org/10.1515/9783110264043 dorsal pancreatic bud http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png - + - + - + EHDAA2 - + XAO @@ -397658,8 +397648,8 @@ https://doi.org/10.1515/9783110264043 - - + + Pancreatic bud that gives rise to the major pancreatic duct. In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG] The ventral pancreatic bud becomes the head and uncinate process, and comes from the hepatic diverticulum[WP] @@ -397687,24 +397677,24 @@ https://doi.org/10.1515/9783110264043 ventral pancreatic bud http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png - + - + - + EHDAA2 - + PMID:16417468 WP @@ -398438,7 +398428,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -398475,14 +398465,14 @@ https://doi.org/10.1515/9783110264043 rete testis http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg - + - + Wikipedia @@ -398901,7 +398891,7 @@ https://doi.org/10.1515/9783110264043 - + A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. Not to be confused with 'dermatome segment of skin'. AAO:0011028 @@ -398928,7 +398918,7 @@ https://doi.org/10.1515/9783110264043 dermatome http://upload.wikimedia.org/wikipedia/commons/f/f3/Gray64.png - + @@ -398941,7 +398931,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2-abduced @@ -399260,7 +399250,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399287,14 +399277,14 @@ https://doi.org/10.1515/9783110264043 biliary ductule - + - + BTO @@ -399385,7 +399375,7 @@ https://doi.org/10.1515/9783110264043 - + The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. consider merging with 'ventricular zone'; note that the MA class probably does not belong here, as this is an embryonic structure The layer of undifferentiated, proliferating cells that line the neural tube lumen @@ -399403,7 +399393,7 @@ https://doi.org/10.1515/9783110264043 neural tube ventricular layer - + @@ -399416,7 +399406,7 @@ https://doi.org/10.1515/9783110264043 - + NCBIBook:NBK10047 @@ -399477,7 +399467,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399501,7 +399491,7 @@ https://doi.org/10.1515/9783110264043 neural tube mantle layer - + @@ -399514,7 +399504,7 @@ https://doi.org/10.1515/9783110264043 - + by division NCBIBook:NBK10047 @@ -399552,7 +399542,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399569,14 +399559,14 @@ https://doi.org/10.1515/9783110264043 neural tube marginal layer - + - + forms from axons @@ -399618,7 +399608,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399643,14 +399633,14 @@ https://doi.org/10.1515/9783110264043 neural tube basal plate - + - + Shh Swenson @@ -399765,7 +399755,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -399778,7 +399768,7 @@ https://doi.org/10.1515/9783110264043 - + The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it. Fusion of right and left medial nasal processes forms a primary palate rostrally and the nasal septum caudally. The incisive bone, including upper incisor teeth and the rostral up- per lip, are derived from the primary palate. The nasal septum consists of bone, cartilage, and a patch of soft tissue membrane that separates right & left halves of the nasal cavity. EHDAA2:0001076 @@ -399799,24 +399789,24 @@ https://doi.org/10.1515/9783110264043 medial nasal prominence http://upload.wikimedia.org/wikipedia/commons/8/85/Gray45.png - + - + - + EHDAA2 - + Wikipedia @@ -400657,7 +400647,7 @@ https://doi.org/10.1515/9783110264043 - + A myocardium trabecular layer that is part of a cardiac ventricle. TODO - check FMA FMA:83511 @@ -400671,14 +400661,14 @@ https://doi.org/10.1515/9783110264043 trabecular layer of ventricle - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -400713,9 +400703,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -400748,34 +400738,34 @@ https://doi.org/10.1515/9783110264043 optic vesicle http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png - + - + - + - + ZFA - + GO-def - + ZFA @@ -400924,8 +400914,8 @@ https://doi.org/10.1515/9783110264043 - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] XAO:0004185 @@ -400938,24 +400928,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0004140 primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -401020,7 +401010,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelial tube that will give rise to the mature heart. the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube. AAO:0010411 @@ -401040,14 +401030,14 @@ https://doi.org/10.1515/9783110264043 heart tube - + - + ZFA-modified @@ -401192,8 +401182,8 @@ https://doi.org/10.1515/9783110264043 - - + + The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. the intraventricular conduction system from the bundle of His to the distal Purkinje fibers, which carries the impulse to the ventricles. HPS @@ -401204,11 +401194,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0004146 His-Purkinje system - + - + @@ -401221,13 +401211,13 @@ https://doi.org/10.1515/9783110264043 - + GO - + PMID:12626327 PMID:21234997 github:michaelerice @@ -401408,8 +401398,8 @@ https://doi.org/10.1515/9783110264043 - - + + An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium. propepicardial Proepicardial clusters in Zebrafish form on the pericardial wall, adjacent to the atrioventricular (AV) junction and near the venous pole[ZFA] @@ -401421,24 +401411,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0004160 proepicardium - + - + - + todo check other taxa - + ZFA @@ -402320,8 +402310,8 @@ https://doi.org/10.1515/9783110264043 - - + + A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]. MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa EMAPA:35469 @@ -402337,24 +402327,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0004220 large intestine smooth muscle - + - + - + MA - + consider merging @@ -402435,7 +402425,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -402472,14 +402462,14 @@ https://doi.org/10.1515/9783110264043 intestine smooth muscle - + - + consider merging @@ -403863,7 +403853,7 @@ https://doi.org/10.1515/9783110264043 - + A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]. MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa EMAPA:35783 @@ -403888,14 +403878,14 @@ https://doi.org/10.1515/9783110264043 small intestine smooth muscle - + - + consider merging @@ -404756,13 +404746,13 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -404778,14 +404768,14 @@ https://doi.org/10.1515/9783110264043 eye muscle - + - + MA @@ -404874,7 +404864,7 @@ https://doi.org/10.1515/9783110264043 - + The bilaminar epithelium formed from the myotome and dermatome. Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis. Within the dermomyotome there is also a medio-lateral difference. The central region makes dermis, the mesenchymal connective tissue of the back skin. The medial region (closest to neural tube) makes epaxial muscle, and the lateral region (furthest from neural tube) makes hypaxial muscle[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768]. Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis.[TAO] @@ -404897,7 +404887,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0004290 dermomyotome - + @@ -404916,7 +404906,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 ZFA @@ -405198,11 +405188,11 @@ https://doi.org/10.1515/9783110264043 - - - - - + + + + + A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]. A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals. [TFD][VHOG] Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG] @@ -405227,55 +405217,55 @@ https://doi.org/10.1515/9783110264043 allantois http://upload.wikimedia.org/wikipedia/commons/a/a5/Gray25.png - + - + - + - + - + - + EHDAA2-modified - + Hymans - + Hymans - + hindgut diverticulum endoderm ISBN:0073040584 - + ISBN:0073040584 @@ -405422,14 +405412,14 @@ https://doi.org/10.1515/9783110264043 - + - + Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition. distinction between trophectoderm and trophoblast unclear/inconsistent in many sources The outer cellular layer of the mammalian blastocyst. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.750, see_Kardong_KV][VHOG] @@ -405447,11 +405437,11 @@ https://doi.org/10.1515/9783110264043 trophectoderm - + - + @@ -405464,13 +405454,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -405873,7 +405863,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -405929,14 +405919,14 @@ https://doi.org/10.1515/9783110264043 pharyngeal arch artery http://upload.wikimedia.org/wikipedia/commons/8/84/Gray473.png - + - + ZFA @@ -406188,7 +406178,7 @@ https://doi.org/10.1515/9783110264043 - + A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. Acellular anatomical structure composed of collagen, Descemet's membrane is secreted as a basement membrane of the corneal endothelium. Located between the stroma and the corneal endothelium, it is approximately 0.15 micrometer thick at 6 months post-fertilization.[ZFIN] @@ -406220,14 +406210,14 @@ https://doi.org/10.1515/9783110264043 Descemet's membrane https://github.com/obophenotype/uberon/issues/15 - + - + Cline et al @@ -407645,12 +407635,12 @@ https://doi.org/10.1515/9783110264043 - + - + A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]. Note placement of MA class based on parthood relationship EMAPA:32688 @@ -407661,14 +407651,14 @@ https://doi.org/10.1515/9783110264043 cardiac muscle tissue of myocardium - + - + MA @@ -407855,21 +407845,21 @@ https://doi.org/10.1515/9783110264043 - + A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. FMA:84429 uberon UBERON:0004525 cardiac muscle tissue of trabecula carnea of right ventricle - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -407898,21 +407888,21 @@ https://doi.org/10.1515/9783110264043 - + A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. FMA:84430 uberon UBERON:0004526 cardiac muscle tissue of trabecula carnea of left ventricle - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -408898,7 +408888,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -408932,7 +408922,7 @@ https://doi.org/10.1515/9783110264043 liver lobule - + @@ -408945,7 +408935,7 @@ https://doi.org/10.1515/9783110264043 - + FMA MA @@ -409211,7 +409201,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -409243,14 +409233,14 @@ https://doi.org/10.1515/9783110264043 interventricular septum membranous part - + - + Wikipedia @@ -409457,8 +409447,8 @@ https://doi.org/10.1515/9783110264043 - - + + The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane. BAMS:RA EMAPA:35721 @@ -409487,25 +409477,25 @@ https://doi.org/10.1515/9783110264043 raphe nuclei http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png - + - + - + GO Wikipedia - + Wikipedia @@ -410062,7 +410052,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410074,7 +410064,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410105,7 +410095,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410128,11 +410118,11 @@ https://doi.org/10.1515/9783110264043 paired limb/fin - + - + @@ -410145,13 +410135,13 @@ https://doi.org/10.1515/9783110264043 - + VSAO - + definitional @@ -410233,7 +410223,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410255,14 +410245,14 @@ https://doi.org/10.1515/9783110264043 pelvic appendage - + - + definitional @@ -410331,7 +410321,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -410355,14 +410345,14 @@ https://doi.org/10.1515/9783110264043 pectoral appendage - + - + definitional @@ -410904,8 +410894,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -410920,25 +410910,25 @@ https://doi.org/10.1515/9783110264043 UBERON:0004737 metanephric collecting duct - + - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships - + Wikipedia-abduced @@ -410966,7 +410956,7 @@ https://doi.org/10.1515/9783110264043 - + A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] EMAPA:37744 @@ -410980,7 +410970,7 @@ https://doi.org/10.1515/9783110264043 Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from skeletal tissue - + @@ -410993,7 +410983,7 @@ https://doi.org/10.1515/9783110264043 - + 2012-08-14 VSAO:0000015 VSAO @@ -411165,7 +411155,7 @@ https://doi.org/10.1515/9783110264043 - + The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]. in contrast to chondrocranium, this structure is entirely cartiliginous. In Chondricthyes this is the same as the neurocranium. FMA:76621 is an undefined fetal structure, so we assume the correct placement is here. Note that this is distinct from MA:0000317 which is the uberon:neurocranium (the part of the cranium that encloses the brain) AAO:0000094 @@ -411187,7 +411177,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0004761 cartilaginous neurocranium - + @@ -411200,7 +411190,7 @@ https://doi.org/10.1515/9783110264043 - + PMC1571569 @@ -411297,7 +411287,7 @@ https://doi.org/10.1515/9783110264043 - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -411313,14 +411303,14 @@ https://doi.org/10.1515/9783110264043 skeletal element - + - + VSAO @@ -411449,7 +411439,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -411488,14 +411478,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004770 articular system - + - + FMA @@ -411610,7 +411600,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a respiratory system [Automatically generated definition]. EMAPA:37576 MA:0001821 @@ -411625,14 +411615,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004779 respiratory system lamina propria - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -411708,7 +411698,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a gastrointestinal system. MA:0001899 NCIT:C49299 @@ -411717,14 +411707,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004780 gastrointestinal system lamina propria - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -411759,7 +411749,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a gallbladder [Automatically generated definition]. EMAPA:35371 FMA:278594 @@ -411778,14 +411768,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004781 gallbladder lamina propria - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -412380,10 +412370,10 @@ https://doi.org/10.1515/9783110264043 - - - - + + + + A mucosa that is part of a gastrointestinal system. BTO:0000546 BTO:0005568 @@ -412399,44 +412389,44 @@ https://doi.org/10.1515/9783110264043 The gut mucosa of amphioxus has insulin-secreting cells. http://www.ncbi.nlm.nih.gov/pubmed/16417468 gastrointestinal system mucosa - + - + - + - + - + PMID:16417468 - + PMID:16417468 - + PMID:16417468 - + BTO-modified @@ -414762,7 +414752,7 @@ https://doi.org/10.1515/9783110264043 - + An endothelium of artery that is part of a respiratory system [Automatically generated definition]. EMAPA:37566 @@ -414783,14 +414773,14 @@ https://doi.org/10.1515/9783110264043 respiratory system arterial endothelium - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -415724,7 +415714,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -415747,14 +415737,14 @@ https://doi.org/10.1515/9783110264043 splanchnopleure http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png - + - + EHDAA2 @@ -415782,7 +415772,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -415805,14 +415795,14 @@ https://doi.org/10.1515/9783110264043 somatopleure http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png - + - + EHDAA2 @@ -415878,9 +415868,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -415901,34 +415891,34 @@ https://doi.org/10.1515/9783110264043 urogenital fold - + - + - + - + EHDAA2 - + Wikipedia - + EHDAA2 @@ -416118,7 +416108,7 @@ https://doi.org/10.1515/9783110264043 - + The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra. we follow EHDAA2 in dividing the UGS into epithelium and lumen EHDAA2:0004061 @@ -416129,14 +416119,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004902 urogenital sinus epithelium - + - + EHDAA2 @@ -416612,8 +416602,8 @@ https://doi.org/10.1515/9783110264043 - - + + EHDAA2:0000171 EMAPA:16561 EMAPA_RETIRED:16565 @@ -416624,11 +416614,11 @@ https://doi.org/10.1515/9783110264043 biliary bud http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png - + - + @@ -416641,13 +416631,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2-modified @@ -417818,7 +417808,7 @@ https://doi.org/10.1515/9783110264043 - + The submucous layer of the wall of the urinary bladder. BTO:0002117 @@ -417837,14 +417827,14 @@ https://doi.org/10.1515/9783110264043 submucosa of urinary bladder - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -417918,7 +417908,7 @@ https://doi.org/10.1515/9783110264043 - + A mucosa that is part of a ureter [Automatically generated definition]. FMA:15894 SCTID:40476001 @@ -417939,14 +417929,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004980 mucosa of ureter - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -419060,7 +419050,7 @@ https://doi.org/10.1515/9783110264043 - + A mucosa that is part of a pyloric antrum [Automatically generated definition]. BTO:0004107 FMA:17055 @@ -419093,14 +419083,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0004997 mucosa of pyloric antrum - + - + BTO @@ -422043,20 +422033,20 @@ https://doi.org/10.1515/9783110264043 - + Missing definition for term UBERON:0005064. Please replace it using linked reference. uberon UBERON:0005064 left ventricular trabecular myocardium - + - + GO @@ -422083,20 +422073,20 @@ https://doi.org/10.1515/9783110264043 - + Missing definition for term UBERON:0005066. Please replace it using linked reference. uberon UBERON:0005066 right ventricular trabecular myocardium - + - + GO @@ -422456,7 +422446,7 @@ https://doi.org/10.1515/9783110264043 - + Missing definition for term UBERON:0005095. Please replace it using linked reference. class added for consistency with GO - consider merging with kidney mesenchyme. uberon @@ -422464,14 +422454,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005095 kidney rudiment - + - + GO @@ -422662,14 +422652,14 @@ https://doi.org/10.1515/9783110264043 - + - + A metanephric nephron is the functional unit of the metanephros[GO]. The primitive form of the vertebrate nephron consists of a vascular filtration surface overlain with podocytes, a specialized coelomic cavity to receive the ultrafiltrate, and a tubule for modification to final urine. Although previously thought to be unique to the vertebrates, this design is now known to be widespread among invertebrates, including most of the protochordates, and especially their larvae.[well established][VHOG] UBERON:0005142 @@ -422678,25 +422668,25 @@ https://doi.org/10.1515/9783110264043 UBERON:0005110 metanephric nephron - + - + - + Wikipedia Wikipedia:Nephron - + Bgee:AN @@ -422723,20 +422713,20 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0001140 uberon UBERON:0005113 metanephric cortex mesenchyme - + - + EHDAA2 @@ -422758,32 +422748,32 @@ https://doi.org/10.1515/9783110264043 - - + + The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]. uberon UBERON:0005115 metanephric cortical collecting duct - + - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -422812,20 +422802,20 @@ https://doi.org/10.1515/9783110264043 - + The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]. uberon UBERON:0005134 metanephric nephron epithelium - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -422892,7 +422882,7 @@ https://doi.org/10.1515/9783110264043 - + A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]. UBERON:0005128 UBERON:0005152 @@ -422900,14 +422890,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005146 metanephric nephron tubule - + - + ISBN:9780878932504 @@ -422935,7 +422925,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -422951,14 +422941,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005147 metanephric renal vesicle - + - + EHDAA2 @@ -423698,7 +423688,7 @@ https://doi.org/10.1515/9783110264043 - + An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]. EMAPA:37513 @@ -423715,14 +423705,14 @@ https://doi.org/10.1515/9783110264043 deferent duct artery - + - + Wikipedia @@ -424498,7 +424488,7 @@ https://doi.org/10.1515/9783110264043 - + Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head. (Source: BioGlossary, www.Biology-Text.com)[TAO] EFO:0003492 @@ -424520,14 +424510,14 @@ https://doi.org/10.1515/9783110264043 head mesenchyme - + - + EHDAA2 @@ -424594,7 +424584,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -424610,14 +424600,14 @@ https://doi.org/10.1515/9783110264043 trunk mesenchyme - + - + EHDAA2 @@ -424657,7 +424647,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -424681,14 +424671,14 @@ https://doi.org/10.1515/9783110264043 renal cortex artery - + - + MA @@ -424740,7 +424730,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -424763,14 +424753,14 @@ https://doi.org/10.1515/9783110264043 renal cortex vein - + - + MA @@ -424801,14 +424791,14 @@ https://doi.org/10.1515/9783110264043 - + + - @@ -424834,24 +424824,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0005270 renal cortex interstitium - + - + - + MA - + MA @@ -424891,7 +424881,7 @@ https://doi.org/10.1515/9783110264043 - + The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. The posterior of the two brain vesicles formed by specialization of the rhombencephalon in the developing embryo, it comprises the medulla oblongata. [TFD][VHOG] @@ -424916,14 +424906,14 @@ https://doi.org/10.1515/9783110264043 myelencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -425291,7 +425281,7 @@ https://doi.org/10.1515/9783110264043 - + The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals[WP]. TODO - check primary vs testis EHDAA2:0002011 @@ -425308,14 +425298,14 @@ https://doi.org/10.1515/9783110264043 testis sex cord - + - + Bgee:AN @@ -425433,13 +425423,13 @@ https://doi.org/10.1515/9783110264043 - + - + The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]. Bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts. In zebrafish and other teleosts, the pronephric nephron and tubules form after the pronephric duct, connecting to the anterior-most tip of the pronephric ducts. Drummond, 2000.[TAO] @@ -425452,14 +425442,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005310 pronephric nephron tubule - + - + GO @@ -425607,7 +425597,7 @@ https://doi.org/10.1515/9783110264043 - + The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]. AAO:0010390 XAO:0000151 @@ -425615,14 +425605,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005319 mesonephric collecting duct - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -425692,7 +425682,7 @@ https://doi.org/10.1515/9783110264043 - + A nephron that is part of a mesonephros. The structure that is the basic functional unit of the kidney.[AAO] AAO:0010387 @@ -425704,14 +425694,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005322 mesonephric nephron - + - + XAO @@ -425795,20 +425785,20 @@ https://doi.org/10.1515/9783110264043 - + The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]. uberon UBERON:0005330 mesonephric nephron epithelium - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -425837,7 +425827,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -425852,14 +425842,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005331 mesonephric renal vesicle - + - + ZFA @@ -426730,7 +426720,7 @@ https://doi.org/10.1515/9783110264043 - + An apical ectodermal ridge that is part of a pectoral appendage bud. An ectodermal thickening at the end of the forelimb bud in the developing embryo. [TFD][VHOG] Apical ectodermal ridge that is part of the pectoral fin bud.[TAO] @@ -426757,14 +426747,14 @@ https://doi.org/10.1515/9783110264043 pectoral appendage apical ectodermal ridge - + - + EHDAA2 @@ -426881,7 +426871,7 @@ https://doi.org/10.1515/9783110264043 - + An apical ectodermal ridge that is part of a pelvic appendage bud. An ectodermal thickening at the end of the hindlimb bud in the developing embryo. [TFD][VHOG] Apical ectodermal ridge that is part of the pelvic fin bud.[TAO] @@ -426904,14 +426894,14 @@ https://doi.org/10.1515/9783110264043 pelvic appendage apical ectodermal ridge - + - + EHDAA2 @@ -427237,7 +427227,7 @@ https://doi.org/10.1515/9783110264043 - + Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. TAO:0002188 ZFA:0001688 @@ -427245,7 +427235,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005427 corneal primordium - + @@ -427264,7 +427254,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -427364,7 +427354,7 @@ https://doi.org/10.1515/9783110264043 - + The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates. the merged ventral aortae of the embryo which supplies blood to the aortic arches[TMD][http://medical-dictionary.thefreedictionary.com/aortic+sac]. EHDAA2:0004145 @@ -427379,7 +427369,7 @@ https://doi.org/10.1515/9783110264043 aortic sac - + @@ -427392,7 +427382,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -427726,7 +427716,7 @@ https://doi.org/10.1515/9783110264043 - + A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]. sulcus limitans BAMS:slim @@ -427737,14 +427727,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005478 sulcus limitans of neural tube - + - + EHDAA2 @@ -428018,7 +428008,7 @@ https://doi.org/10.1515/9783110264043 - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. BTO:0006179 EHDAA2:0001512 @@ -428037,14 +428027,14 @@ https://doi.org/10.1515/9783110264043 primitive heart tube - + - + ZFA @@ -428126,7 +428116,7 @@ https://doi.org/10.1515/9783110264043 - + Cranial neural crest which gives rise to the trigeminal ganglion. todo - compare ZFA and EHDAA2 representation We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG] @@ -428143,7 +428133,7 @@ https://doi.org/10.1515/9783110264043 trigeminal neural crest - + @@ -428162,7 +428152,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -428188,7 +428178,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -428217,7 +428207,7 @@ https://doi.org/10.1515/9783110264043 gonad primordium - + @@ -428230,7 +428220,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -428288,15 +428278,15 @@ https://doi.org/10.1515/9783110264043 - + - - + + Somite located in the head region, caudal to the otic vesicle. in humans this includes somites 1-4 They provide the epaxial and hypaxial muscles of the neck, the pharyngeal and laryngeal muscles that develop in the caudal branchial arches and the musculature of the tongue. Despite their localisation in the head, myogenic precursors from occipital somites essentially follow the trunk programmes (E. H. Walters and S. D., unpublished). during evolution, have been secondarily incorporated into the head (Gans and Northcutt, 1983) @@ -428310,24 +428300,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0005594 head somite - + - + - + EHDAA2 - + EHDAA2 @@ -428374,7 +428364,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -428394,7 +428384,7 @@ https://doi.org/10.1515/9783110264043 lung primordium - + @@ -428407,7 +428397,7 @@ https://doi.org/10.1515/9783110264043 - + XAO @@ -428480,8 +428470,8 @@ https://doi.org/10.1515/9783110264043 - - + + The portion of mesentery attached to the greater curvature of the stomach is named the dorsal mesentery (or dorsal mesogastrium, when referring to the portion at the stomach), and the part which suspends the colon is termed the mesocolon. The dorsal mesogastrium develops into the greater omentum. The dorsal sheet of the primitive mesentery that encloses the stomach. The greater omentum develops from the dorsal mesogastrium. [TFD][VHOG] EHDAA2:0000416 @@ -428497,11 +428487,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0005602 dorsal mesogastrium - + - + @@ -428514,13 +428504,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -428558,8 +428548,8 @@ https://doi.org/10.1515/9783110264043 - - + + EMAPA:16844 MA:0001636 VHOG:0000215 @@ -428569,24 +428559,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0005604 extrahepatic part of hepatic duct - + - + - + MA - + MA @@ -429275,13 +429265,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0000314 uberon UBERON:0005667 connecting stalk mesoderm - + @@ -429294,7 +429284,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -429802,7 +429792,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -429815,7 +429805,7 @@ https://doi.org/10.1515/9783110264043 - + A mesoderm that has the potential to develop into a pronephros. Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.[AAO] AAO:0011090 @@ -429834,24 +429824,24 @@ https://doi.org/10.1515/9783110264043 the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney pronephric mesoderm - + - + - + ZFA - + Bgee:AN @@ -429938,7 +429928,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0000474 EMAPA:31862 EMAPA:31863 @@ -429950,7 +429940,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005728 extraembryonic mesoderm - + @@ -429963,7 +429953,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -430101,7 +430091,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -430117,14 +430107,14 @@ https://doi.org/10.1515/9783110264043 paired limb/fin field - + - + ISBN:9780878932504 ZFA-inferred @@ -431060,7 +431050,7 @@ https://doi.org/10.1515/9783110264043 - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -431070,7 +431060,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005856 developing mesenchymal condensation - + @@ -431089,7 +431079,7 @@ https://doi.org/10.1515/9783110264043 - + AEO-modified-relation @@ -431111,7 +431101,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -431132,7 +431122,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005863 cartilaginous condensation - + @@ -431145,7 +431135,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -431196,7 +431186,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -431218,14 +431208,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005865 pre-muscle condensation - + - + AEO @@ -431236,7 +431226,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -431256,7 +431246,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0005866 pre-cartilage condensation - + @@ -431269,7 +431259,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -431418,8 +431408,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -431458,24 +431448,24 @@ https://doi.org/10.1515/9783110264043 undifferentiated genital tubercle http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png - + - + - + EHDAA2 - + https://github.com/obophenotype/uberon/issues/1230 @@ -431563,8 +431553,8 @@ https://doi.org/10.1515/9783110264043 - - + + The epithelial lining of the surface of the coelom. EHDAA2:0004049 used to be called 'coelomic epithelium' but is now 'gonadal ridge mesothelium' Wikipedia:Coelomic_epithelium @@ -431575,24 +431565,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0005891 coelomic epithelium - + - + - + XAO - + XAO @@ -432029,7 +432019,7 @@ https://doi.org/10.1515/9783110264043 - + trabecula trabecular cartilage EFO:0003677 @@ -432041,7 +432031,7 @@ https://doi.org/10.1515/9783110264043 neurocranial trabecula - + @@ -432054,7 +432044,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -432156,7 +432146,7 @@ https://doi.org/10.1515/9783110264043 - + Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk. infundibulum EMAPA:37926 @@ -432179,14 +432169,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0005953 outflow part of right ventricle - + - + PMID:17276708 @@ -432501,7 +432491,7 @@ https://doi.org/10.1515/9783110264043 - + A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]. EMAPA:16076 amnionic fold @@ -432510,14 +432500,14 @@ https://doi.org/10.1515/9783110264043 amniotic fold - + - + ISBN:0073040584 @@ -432712,7 +432702,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -432732,14 +432722,14 @@ https://doi.org/10.1515/9783110264043 atrium myocardial trabecula - + - + ZFA @@ -432791,7 +432781,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -432815,14 +432805,14 @@ https://doi.org/10.1515/9783110264043 atrioventricular septum - + - + PMID:15797462 Wikipedia @@ -432869,7 +432859,7 @@ https://doi.org/10.1515/9783110264043 - + The paired arteries that carry blood to the yolk sac from the dorsal aorta. EHDAA2:0002208 EMAPA:16207 @@ -432881,14 +432871,14 @@ https://doi.org/10.1515/9783110264043 vitelline artery http://upload.wikimedia.org/wikipedia/commons/5/55/Gray31.png - + - + ventral branch @@ -433160,7 +433150,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433191,14 +433181,14 @@ https://doi.org/10.1515/9783110264043 cervical region of vertebral column - + - + FMA @@ -433276,7 +433266,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433310,14 +433300,14 @@ https://doi.org/10.1515/9783110264043 thoracic region of vertebral column - + - + FMA @@ -433498,7 +433488,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433518,14 +433508,14 @@ https://doi.org/10.1515/9783110264043 subdivision of vertebral column - + - + FMA @@ -433607,7 +433597,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433640,14 +433630,14 @@ https://doi.org/10.1515/9783110264043 aortico-pulmonary spiral septum http://upload.wikimedia.org/wikipedia/commons/b/b9/Gray470.png - + - + PMID:6844926 Wikipedia @@ -433702,7 +433692,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433746,14 +433736,14 @@ https://doi.org/10.1515/9783110264043 buccopharyngeal membrane http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png - + - + EHDAA2 @@ -433800,7 +433790,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -433841,14 +433831,14 @@ https://doi.org/10.1515/9783110264043 cloacal membrane http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png - + - + Wikipedia @@ -433930,9 +433920,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -433949,34 +433939,34 @@ https://doi.org/10.1515/9783110264043 ethmoid bone primordium - + - + - + - + FMA - + AAO - + EHDAA2 @@ -433997,7 +433987,7 @@ https://doi.org/10.1515/9783110264043 - + A differentiated genital tubercle that is part of a female reproductive system. EHDAA:8118 EMAPA:18680 @@ -434009,14 +433999,14 @@ https://doi.org/10.1515/9783110264043 female genital tubercle - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -434238,8 +434228,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -434258,24 +434248,24 @@ https://doi.org/10.1515/9783110264043 future central tendon - + - + - + EHDAA2 - + mesenchyme cranial part Wikipedia @@ -434311,7 +434301,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -434335,14 +434325,14 @@ https://doi.org/10.1515/9783110264043 future spinal cord - + - + EHDAA2 @@ -434388,8 +434378,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -434407,24 +434397,24 @@ https://doi.org/10.1515/9783110264043 gallbladder primordium - + - + - + EMAPA - + EHDAA2 @@ -434452,7 +434442,7 @@ https://doi.org/10.1515/9783110264043 - + A differentiated genital tubercle that is part of a male reproductive system. EHDAA:8138 EMAPA:17969 @@ -434465,14 +434455,14 @@ https://doi.org/10.1515/9783110264043 male genital tubercle - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -434560,7 +434550,7 @@ https://doi.org/10.1515/9783110264043 - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -434575,7 +434565,7 @@ https://doi.org/10.1515/9783110264043 notochordal plate - + @@ -434588,7 +434578,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -434625,7 +434615,7 @@ https://doi.org/10.1515/9783110264043 - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -434642,14 +434632,14 @@ https://doi.org/10.1515/9783110264043 The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -434728,7 +434718,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -434761,7 +434751,7 @@ https://doi.org/10.1515/9783110264043 pleuroperitoneal canal - + @@ -434774,7 +434764,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -434806,8 +434796,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -434838,24 +434828,24 @@ https://doi.org/10.1515/9783110264043 The embryonic ventricle or primitive ventricle of the developing heart gives rise to the trabeculated parts of the left and right ventricles. In contrast, the smooth parts of the left and right ventricles originate from the embryological bulbus cordis. The primitive ventricle becomes divided by a septum, the septum inferius or ventricular septum, which grows upward from the lower part of the ventricle, its position being indicated on the surface of the heart by a furrow. Its dorsal part increases more rapidly than its ventral portion, and fuses with the dorsal part of the septum intermedium. For a time an interventricular foramen exists above its ventral portion, but this foramen is ultimately closed by the fusion of the aortic septum with the ventricular septum[WP] future cardiac ventricle - + - + - + ZFA - + EMAPA @@ -434905,8 +434895,8 @@ https://doi.org/10.1515/9783110264043 - - + + A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]. check difference between splenic and spleen in EMAPA; note that in EHDAA2 the class 'spleen' refers to the mesenchyme UBERON:0009750 @@ -434923,11 +434913,11 @@ https://doi.org/10.1515/9783110264043 spleen primordium - + - + @@ -434940,13 +434930,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2-modified - + XAO @@ -435011,7 +435001,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA:924 EMAPA:16663 RETIRED_EHDAA2:0002089 @@ -435023,14 +435013,14 @@ https://doi.org/10.1515/9783110264043 See: https://github.com/obophenotype/mouse-anatomy-ontology/issues/13 and https://github.com/obophenotype/uberon/issues/693 -- consider merging into trigeminal ganglion, as this complicates the model future trigeminal ganglion - + - + EHDAA2 @@ -435371,7 +435361,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -435404,14 +435394,14 @@ https://doi.org/10.1515/9783110264043 os penis - + - + Wikipedia @@ -435465,7 +435455,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -435513,14 +435503,14 @@ https://doi.org/10.1515/9783110264043 os clitoris - + - + Wikipedia @@ -437157,7 +437147,7 @@ https://doi.org/10.1515/9783110264043 - + Erectile tissue at the end of the clitoris, which is continuous with the intermediate part of the vestibulovaginal bulbs[BTO]. The clitoral glans (glans clitoridis) is an external portion of the clitoris[WP]. BTO:0003117 EMAPA:19170 @@ -437176,14 +437166,14 @@ https://doi.org/10.1515/9783110264043 glans clitoris http://upload.wikimedia.org/wikipedia/commons/8/8c/Clitoris_inner_anatomy.gif - + - + cjm @@ -437348,7 +437338,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -437361,7 +437351,7 @@ https://doi.org/10.1515/9783110264043 - + The three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers. In mammals, the diaphragm muscle divides the thoracoabdominal cavity into thorax and abdomen. In most mammals, the diaphragm is a flat sheet with muscle fibers radiating outward from a central tendon, and the diaphragm's apposition to the cranial surface of the liver gives it a dome-shape. Muscle fiber contraction reduces the curvature of the dome, thereby expanding the thoracic cavity and aspirating air into the lungs.[well established][VHOG] EMAPA:17702 @@ -437379,24 +437369,24 @@ https://doi.org/10.1515/9783110264043 central tendon of diaphragm - + - + - + VHOG - + definitional @@ -437935,7 +437925,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -437956,7 +437946,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0006815 areolar connective tissue - + @@ -437969,7 +437959,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -438234,7 +438224,7 @@ https://doi.org/10.1515/9783110264043 - + A muscular coat that is part of a ureter. EMAPA:28811 FMA:15893 @@ -438250,14 +438240,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0006855 muscular coat of ureter - + - + FMA @@ -438548,7 +438538,7 @@ https://doi.org/10.1515/9783110264043 - + A head mesenchyme that develops_from a mesoderm. merged in 'head mesoderm' from XAO/AAO and EFO here. Partially implements https://github.com/obophenotype/uberon/wiki/The-neural-crest NC meeting scheme AAO:0011051 @@ -438576,7 +438566,7 @@ https://doi.org/10.1515/9783110264043 head mesenchyme from mesoderm - + @@ -438589,7 +438579,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 XAO @@ -439299,7 +439289,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -439345,14 +439335,14 @@ https://doi.org/10.1515/9783110264043 efferent duct http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg - + - + FMA @@ -439418,7 +439408,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -439446,14 +439436,14 @@ https://doi.org/10.1515/9783110264043 male genital duct https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb - + - + FMA-abduced-lr @@ -439634,7 +439624,7 @@ https://doi.org/10.1515/9783110264043 - + The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis. CALOHA:TS-1246 @@ -439656,14 +439646,14 @@ https://doi.org/10.1515/9783110264043 ovary stroma - + - + FMA @@ -440260,7 +440250,7 @@ https://doi.org/10.1515/9783110264043 - + Cranial neural crest that migrates into the mandibular arch. TAO:0007064 XAO:0000024 @@ -440269,7 +440259,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007098 mandibular neural crest - + @@ -440282,7 +440272,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -440301,7 +440291,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -440312,7 +440302,7 @@ https://doi.org/10.1515/9783110264043 - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -440327,14 +440317,14 @@ https://doi.org/10.1515/9783110264043 Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -440369,8 +440359,8 @@ https://doi.org/10.1515/9783110264043 - - + + One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta. The mouse and human placentas have labyrinthine and villous types of interdigitation between maternal and fetal tissues, respectively The bulk of the villi consist of connective tissues in which blood vessels are found. Most of the cells in the connective tissue core of the villi are fibroblasts. Macrophages known as Hofbauer cells are also present. @@ -440398,24 +440388,24 @@ https://doi.org/10.1515/9783110264043 chorionic villus http://upload.wikimedia.org/wikipedia/commons/1/1e/Gray29.png - + - + - + BTO - + MP-def @@ -441475,7 +441465,7 @@ https://doi.org/10.1515/9783110264043 - + relationship to Meckel's cartilage to be added Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG] EHDAA2:0000031 @@ -441489,14 +441479,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007237 1st arch mandibular component - + - + EHDAA2 @@ -441534,7 +441524,7 @@ https://doi.org/10.1515/9783110264043 - + relationship to palatoquadrate to be added Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG] EHDAA2:0000038 @@ -441545,14 +441535,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007238 1st arch maxillary component - + - + EHDAA2 @@ -441650,7 +441640,7 @@ https://doi.org/10.1515/9783110264043 - + A tunica adventitia that is part of a artery. EMAPA:36295 EV:0100030 @@ -441662,14 +441652,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007240 tunica adventitia of artery - + - + FMA @@ -442115,7 +442105,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442136,14 +442126,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007272 pectoral appendage skeleton - + - + VSAO @@ -442178,7 +442168,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442196,14 +442186,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007273 pelvic appendage skeleton - + - + VSAO @@ -442236,8 +442226,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -442264,24 +442254,24 @@ https://doi.org/10.1515/9783110264043 presumptive hindbrain - + - + - + XAO-abduced - + cjm @@ -442338,7 +442328,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442352,14 +442342,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007278 presumptive sinus venosus - + - + ZFA @@ -442445,7 +442435,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442464,14 +442454,14 @@ https://doi.org/10.1515/9783110264043 presumptive midbrain hindbrain boundary - + - + ZFA @@ -442510,7 +442500,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442527,14 +442517,14 @@ https://doi.org/10.1515/9783110264043 presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -442633,7 +442623,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -442659,7 +442649,7 @@ https://doi.org/10.1515/9783110264043 presumptive paraxial mesoderm - + @@ -442675,7 +442665,7 @@ https://doi.org/10.1515/9783110264043 - + https://github.com/obophenotype/uberon/issues/1277 @@ -443069,7 +443059,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -443115,7 +443105,7 @@ https://doi.org/10.1515/9783110264043 pancreatic duct http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png - + @@ -443128,7 +443118,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -443269,7 +443259,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -443296,14 +443286,14 @@ https://doi.org/10.1515/9783110264043 outer epithelium - + - + Wikipedia:Epidermis_(zoology) @@ -443834,7 +443824,7 @@ https://doi.org/10.1515/9783110264043 - + A collection of connected epithelial tubes with a single portal. AEO:0000117 EHDAA2:0003117 @@ -443843,7 +443833,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007501 arborizing epithelial duct system - + @@ -443856,7 +443846,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -443992,7 +443982,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -444000,7 +443990,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007524 dense mesenchyme tissue - + @@ -444013,7 +444003,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -444258,7 +444248,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -444278,14 +444268,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007616 layer of synovial tissue - + - + BTO @@ -444498,7 +444488,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -444524,7 +444514,7 @@ https://doi.org/10.1515/9783110264043 trigeminal nuclear complex http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png - + @@ -444537,7 +444527,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -444786,7 +444776,7 @@ https://doi.org/10.1515/9783110264043 - + EFO:0003626 EHDAA2:0001457 EHDAA:962 @@ -444805,14 +444795,14 @@ https://doi.org/10.1515/9783110264043 early pharyngeal endoderm http://dev.biologists.org/content/128/22/4573.full - + - + cjm @@ -444950,26 +444940,26 @@ https://doi.org/10.1515/9783110264043 - + - + An endothelium that is part of a umbilical artery. BTO:0000857 uberon UBERON:0007778 umbilical artery endothelium - + - + BTO @@ -445099,7 +445089,7 @@ https://doi.org/10.1515/9783110264043 - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -445118,14 +445108,14 @@ https://doi.org/10.1515/9783110264043 vascular system - + - + MA @@ -445159,7 +445149,7 @@ https://doi.org/10.1515/9783110264043 - + A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord. TODO - this is currently defined as a bridge of mesoderm, but in EHDAA2 is extraembryonic structure split into mesoderm and blood vessels BTO:0004705 @@ -445169,7 +445159,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007806 connecting stalk - + @@ -445182,7 +445172,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -445221,7 +445211,7 @@ https://doi.org/10.1515/9783110264043 - + A vasculature that is part of a connecting stalk. EHDAA2:0000313 connecting stalk blood vessels @@ -445231,14 +445221,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007807 connecting stalk vasculature - + - + EHDAA2 @@ -445430,7 +445420,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -445488,14 +445478,14 @@ https://doi.org/10.1515/9783110264043 post-anal tail - + - + possible exception in hemichordates cjm @@ -445660,7 +445650,7 @@ https://doi.org/10.1515/9783110264043 - + Mesentery that is located in the peritoneum. FMA:20570 TAO:0005129 @@ -445670,14 +445660,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0007826 peritoneal mesentery - + - + FMA @@ -446044,7 +446034,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -446087,14 +446077,14 @@ https://doi.org/10.1515/9783110264043 pelvic girdle skeleton http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray242.png - + - + PMID:21455939 @@ -446258,8 +446248,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -446285,11 +446275,11 @@ https://doi.org/10.1515/9783110264043 cartilage element - + - + @@ -446302,13 +446292,13 @@ https://doi.org/10.1515/9783110264043 - + VSAO - + VSAO @@ -446517,12 +446507,12 @@ https://doi.org/10.1515/9783110264043 - + - + A bone that is part of a craniocervical region. EMAPA:37245 MA:0000569 @@ -446532,7 +446522,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0007914 bone of craniocervical region - + @@ -446545,7 +446535,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -446924,12 +446914,12 @@ https://doi.org/10.1515/9783110264043 - + - + Musculature system of the pharyngeal and head regions. in MA this is restricted to skeletal muscles EMAPA:37259 @@ -446943,7 +446933,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008229 craniocervical region musculature - + @@ -446956,7 +446946,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -447003,8 +446993,8 @@ https://doi.org/10.1515/9783110264043 - - + + Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax. EMAPA:37234 FMA:24217 @@ -447020,25 +447010,25 @@ https://doi.org/10.1515/9783110264043 UBERON:0008231 dorsal thoracic segment of trunk - + - + - + FMA MA - + FMA @@ -447099,13 +447089,13 @@ https://doi.org/10.1515/9783110264043 - + - + A muscle of back that is part of a dorsal thoracic segment of trunk. EMAPA:37261 MA:0000508 @@ -447114,7 +447104,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008243 upper back muscle - + @@ -447127,7 +447117,7 @@ https://doi.org/10.1515/9783110264043 - + MA @@ -447340,7 +447330,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of a duodenum. CALOHA:TS-2087 @@ -447354,14 +447344,14 @@ https://doi.org/10.1515/9783110264043 duodenal epithelium - + - + FMA @@ -447462,7 +447452,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -447473,7 +447463,7 @@ https://doi.org/10.1515/9783110264043 - + An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers. EHDAA2:0000444 EHDAA:42 @@ -447489,14 +447479,14 @@ https://doi.org/10.1515/9783110264043 The epiblast cells (appearing on day 8 of human embryonic development) make up a columnar epithelium with dense microvilli on the apical surface. During gastrulation, the epiblast cells undergo epithelial-to-mesenchymal transition and delaminate to become the loose mesenchyme of the primitive streak. The epiblast is present in postimplantation mouse embryos between E5.5-E7.5. inner cell mass derived epiblast - + - + Wikipedia @@ -447713,7 +447703,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -447728,7 +447718,7 @@ https://doi.org/10.1515/9783110264043 neural tube derived brain https://github.com/obophenotype/uberon/issues/338 - + @@ -447741,7 +447731,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -447770,7 +447760,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -447790,14 +447780,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0008824 duct of epididymis - + - + FMA @@ -447835,8 +447825,8 @@ https://doi.org/10.1515/9783110264043 - - + + An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts. in mice, the hepatic diverticulum forms by E9 and expands into an obvious liver bud by E10 The caudal part of the septum transversum is invaded by the hepatic diverticulum which divides within it to form the liver and thus gives rise to the ventral mesentery of the foregut. @@ -447855,11 +447845,11 @@ https://doi.org/10.1515/9783110264043 hepatic diverticulum http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png - + - + @@ -447872,14 +447862,14 @@ https://doi.org/10.1515/9783110264043 - + caudal part EHDAA2 - + EHDAA2 @@ -447918,13 +447908,13 @@ https://doi.org/10.1515/9783110264043 - + BTO:0001642 uberon UBERON:0008836 liver bud - + @@ -447937,7 +447927,7 @@ https://doi.org/10.1515/9783110264043 - + http://www.stembook.org/node/512 @@ -447954,7 +447944,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -447966,10 +447956,10 @@ https://doi.org/10.1515/9783110264043 - + + + - - Dense regular connective tissue connecting two or more adjacent skeletal elements[VSAO,modified]. logical definition deliberately made strict to avoid classifying MA:spiral ligament as both nonskeletal and skeletal. see https://github.com/obophenotype/mouse-anatomy-ontology/issues/71 Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ.[VSAO] @@ -447994,44 +447984,44 @@ https://doi.org/10.1515/9783110264043 skeletal ligament https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg - + - + - + - + - + AEO - + AEO - + bones or cartilage organs - + VSAO @@ -448160,7 +448150,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -448187,14 +448177,14 @@ https://doi.org/10.1515/9783110264043 stomach muscularis externa - + - + MA-abduced @@ -448240,7 +448230,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -448272,7 +448262,7 @@ https://doi.org/10.1515/9783110264043 pyloric canal https://upload.wikimedia.org/wikipedia/commons/3/33/Illu_stomach.jpg - + @@ -448285,7 +448275,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia @@ -448339,7 +448329,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -448364,7 +448354,7 @@ https://doi.org/10.1515/9783110264043 pyloric gastric gland http://upload.wikimedia.org/wikipedia/commons/b/bf/Gray1054.png - + @@ -448377,7 +448367,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia:Tubular_gland @@ -448437,7 +448427,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -448470,14 +448460,14 @@ https://doi.org/10.1515/9783110264043 hypodermis skeletal muscle layer - + - + MP-def @@ -448659,8 +448649,8 @@ https://doi.org/10.1515/9783110264043 - - + + Subdivision of endoskeleton derived from pharyngeal arches. @@ -448693,24 +448683,24 @@ https://doi.org/10.1515/9783110264043 splanchnocranium http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg - + - + - + https://github.com/obophenotype/uberon/issues/83 - + redundant Grays PMID:11237469 @@ -448828,13 +448818,13 @@ https://doi.org/10.1515/9783110264043 - + - + Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]. Intramembranous bone that forms superficially in the organism.[TAO] other AOs are not yet in sync with this classification @@ -448849,7 +448839,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008907 dermal bone - + @@ -448868,7 +448858,7 @@ https://doi.org/10.1515/9783110264043 - + VSAO @@ -448980,13 +448970,13 @@ https://doi.org/10.1515/9783110264043 - + - + A parenchyma that is part of a lung. EMAPA:35522 FMA:27360 @@ -448999,7 +448989,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008946 lung parenchyma - + @@ -449012,7 +449002,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -449141,12 +449131,12 @@ https://doi.org/10.1515/9783110264043 - + - + The functional tissue of the kidney, consisting of the nephrons. BTO:0003604 FMA:15574 @@ -449157,7 +449147,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0008987 renal parenchyma - + @@ -449170,7 +449160,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -449837,13 +449827,13 @@ https://doi.org/10.1515/9783110264043 - + - + Cranial ganglion which develops from an epibranchial placode. BTO:0006250 TAO:0001555 @@ -449854,7 +449844,7 @@ https://doi.org/10.1515/9783110264043 Epibranchial ganglia orchestrate the development of the cranial neurogenic crest epibranchial ganglion - + @@ -449867,7 +449857,7 @@ https://doi.org/10.1515/9783110264043 - + NCBIBook:NBK53175 @@ -449919,8 +449909,8 @@ https://doi.org/10.1515/9783110264043 - - + + Endocardium that is part of the right atrium. EHDAA2:0000274 FMA:7281 @@ -449934,24 +449924,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009129 right atrium endocardium - + - + - + EHDAA2 - + EHDAA2 @@ -450115,7 +450105,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -450132,14 +450122,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -450155,7 +450145,7 @@ https://doi.org/10.1515/9783110264043 - + EMAPA:16549 RETIRED_EHDAA2:0001454 pharyngeal region @@ -450163,14 +450153,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009145 pharyngeal region of foregut - + - + EHDAA2 @@ -450207,8 +450197,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -450222,11 +450212,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0009191 sphenoid bone pre-cartilage condensation - + - + @@ -450245,13 +450235,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -450386,12 +450376,12 @@ https://doi.org/10.1515/9783110264043 - + - + Mesenchyme that is part of a medial nasal prominence. EHDAA2:0001077 EMAPA:16810 @@ -450400,14 +450390,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009204 medial nasal process mesenchyme - + - + EHDAA2 @@ -450642,7 +450632,7 @@ https://doi.org/10.1515/9783110264043 - + A portion of mesenchymal tissue associated with an individual pharyngeal arch. this represents a part of the entire arch mesenchyme (UBERON:0010046), and is therefore a superclass of the individual arch mesenchyme classes. Alternate definition: primordial embryonic connective tissue associated with the branchial arches, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to facial and cranial nerve-associated structures. EMAPA:32755 @@ -450654,7 +450644,7 @@ https://doi.org/10.1515/9783110264043 pharyngeal arch mesenchymal region - + @@ -450667,7 +450657,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -450714,14 +450704,14 @@ https://doi.org/10.1515/9783110264043 - + - + An epithelium that is part of a foregut-midgut junction. EHDAA2:0000573 EMAPA:16564 @@ -450730,24 +450720,24 @@ https://doi.org/10.1515/9783110264043 epithelium of foregut-midgut junction - + - + - + EHDAA2 - + EHDAA2 @@ -451196,7 +451186,7 @@ https://doi.org/10.1515/9783110264043 - + A submucosa that is part of a intestine. FMA:15696 submucosa of intestine @@ -451204,14 +451194,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009566 intestinal submucosa - + - + FMA @@ -451424,7 +451414,7 @@ https://doi.org/10.1515/9783110264043 - + A sulcus limitans of neural tube that is part of a future medulla oblongata. EHDAA2:0001100 EMAPA:17561 @@ -451432,14 +451422,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009576 medulla oblongata sulcus limitans - + - + EHDAA2 @@ -451615,12 +451605,12 @@ https://doi.org/10.1515/9783110264043 - + - + Mesenchyme that is part of a 1st arch mandibular component. UBERON:0010043 EHDAA2:0000034 @@ -451633,14 +451623,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009584 1st arch mandibular mesenchyme - + - + EMAPA @@ -451756,9 +451746,9 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -451772,7 +451762,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0009611 midbrain neural plate - + @@ -451781,20 +451771,20 @@ https://doi.org/10.1515/9783110264043 - + - + ZFA - + ZFA @@ -451809,9 +451799,9 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -451825,7 +451815,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0009614 hindbrain neural plate - + @@ -451834,20 +451824,20 @@ https://doi.org/10.1515/9783110264043 - + - + ZFA - + ZFA @@ -451863,14 +451853,14 @@ https://doi.org/10.1515/9783110264043 - + - + TODO - developmental relationships for lines TAO:0007044 ZFA:0007044 @@ -451880,24 +451870,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009615 midbrain hindbrain boundary neural plate - + - + - + ZFA - + https://github.com/obophenotype/uberon/issues/438 Bgee:AN @@ -451931,14 +451921,14 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -451963,24 +451953,24 @@ https://doi.org/10.1515/9783110264043 presumptive midbrain - + - + - + ZFA - + ZFA @@ -452026,7 +452016,7 @@ https://doi.org/10.1515/9783110264043 - + Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles. A major contributor to neurocranium [PMID:16313393] EHDAA2:0000736 @@ -452043,14 +452033,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009617 head paraxial mesoderm - + - + EHDAA2 @@ -452103,7 +452093,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -452111,14 +452101,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -452189,7 +452179,7 @@ https://doi.org/10.1515/9783110264043 - + A basement membrane that is part of a nephron tubule. EMAPA:37490 MA:0001680 @@ -452203,14 +452193,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009651 nephron tubule basement membrane - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -452383,7 +452373,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004566 EMAPA:32911 MA:0003203 @@ -452394,14 +452384,14 @@ https://doi.org/10.1515/9783110264043 gut mesentery https://github.com/obophenotype/uberon/issues/509 - + - + EHDAA2 @@ -452488,8 +452478,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -452506,24 +452496,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009670 rectal lumen - + - + - + cjm - + EHDAA2 @@ -452547,9 +452537,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + EHDAA2:0001371 uberon @@ -452559,15 +452549,15 @@ https://doi.org/10.1515/9783110264043 dorsal pancreas - + - + - + @@ -452580,19 +452570,19 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 - + cjm @@ -452604,9 +452594,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + EHDAA2:0001393 uberon @@ -452616,15 +452606,15 @@ https://doi.org/10.1515/9783110264043 ventral pancreas - + - + - + @@ -452637,19 +452627,19 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 - + cjm @@ -452676,8 +452666,8 @@ https://doi.org/10.1515/9783110264043 - - + + Any endocardium that is part of the right ventricle of the heart. Endocardium of ventricle which is continuous tricuspid valve, pulmonary valve and with the tunica intima of the pulmonary trunk. EHDAA2:0002188 @@ -452694,24 +452684,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009712 endocardium of right ventricle - + - + - + EHDAA2 - + FMA @@ -452774,7 +452764,7 @@ https://doi.org/10.1515/9783110264043 - + Any endocardium that is part of the left ventricle of the heart. Endocardium of ventricle which is continuous with mitral valve, aortic valve, atrioventricular septum and the tunica intima of the aorta. EHDAA2:0002182 @@ -452790,14 +452780,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009713 endocardium of left ventricle - + - + FMA @@ -452889,7 +452879,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -452904,14 +452894,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009722 entire pharyngeal arch endoderm - + - + EHDAA2 @@ -453114,7 +453104,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -453127,7 +453117,7 @@ https://doi.org/10.1515/9783110264043 - + A serous sac that has the pleura and the pleural cavity as parts. despite its name the class EHDAA2:0004737 is not a true cavity, it corresponds to what we call the sac EHDAA2:0004737 @@ -453138,24 +453128,24 @@ https://doi.org/10.1515/9783110264043 pleural sac - + - + - + FMA - + FMA-abduced-lr @@ -453268,7 +453258,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -453287,14 +453277,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0009844 urogenital sinus lumen - + - + EHDAA2 @@ -453309,7 +453299,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -453325,7 +453315,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0009845 urogenital sinus mesenchyme - + @@ -453337,7 +453327,7 @@ https://doi.org/10.1515/9783110264043 - + PMID:18977204 @@ -453379,8 +453369,8 @@ https://doi.org/10.1515/9783110264043 - - + + An epithelium that is part of a embryonic cloaca. cloacal epithelium EHDAA2:0004585 @@ -453388,24 +453378,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0009846 embryonic cloacal epithelium - + - + - + EHDAA2 - + EHDAA2 @@ -453638,7 +453628,7 @@ https://doi.org/10.1515/9783110264043 - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -453648,14 +453638,14 @@ https://doi.org/10.1515/9783110264043 anterior lateral plate mesoderm - + - + ZFA @@ -453671,7 +453661,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -453701,7 +453691,7 @@ https://doi.org/10.1515/9783110264043 medullary ray - + @@ -453714,7 +453704,7 @@ https://doi.org/10.1515/9783110264043 - + MP @@ -453968,9 +453958,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -453990,34 +453980,34 @@ https://doi.org/10.1515/9783110264043 UBERON:0009889 secondary heart field - + - + - + - + GO:0003129 - + PMID:17276708 - + PMID:17276708 @@ -454288,7 +454278,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -454327,14 +454317,14 @@ https://doi.org/10.1515/9783110264043 Alternate definition: One of the subdivisions of the kidney, consisting of a medullary ray and that portion of the convoluted port (renal corpuscles and convoluted tubules) associated with its collecting duct. -http://www.mondofacto.com/facts/dictionary?lobulus+corticalis+renalis renal lobule - + - + FMA @@ -454524,14 +454514,14 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0001315 EHDAA:1122 uberon UBERON:0009920 optic neural crest - + @@ -454544,7 +454534,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -454718,10 +454708,10 @@ https://doi.org/10.1515/9783110264043 - + - - + + @@ -454741,7 +454731,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0009958 bladder lumen - + @@ -454750,30 +454740,30 @@ https://doi.org/10.1515/9783110264043 - + - + - + FMA - + FMA - + EHDAA2 @@ -454883,7 +454873,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -454915,14 +454905,14 @@ https://doi.org/10.1515/9783110264043 ureteropelvic junction - + - + MP @@ -454966,7 +454956,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -454999,14 +454989,14 @@ https://doi.org/10.1515/9783110264043 ureterovesical junction - + - + MP @@ -455318,8 +455308,8 @@ https://doi.org/10.1515/9783110264043 - - + + The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells. EHDAA2:0001459 EMAPA:16550 @@ -455331,11 +455321,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0010046 entire pharyngeal arch associated mesenchyme - + - + @@ -455348,13 +455338,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + cjm @@ -455535,9 +455525,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -455551,34 +455541,34 @@ https://doi.org/10.1515/9783110264043 UBERON:0010083 future dermis - + - + - + - + EHDAA2 - + EHDAA2 - + XAO @@ -455605,9 +455595,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + @@ -455620,34 +455610,34 @@ https://doi.org/10.1515/9783110264043 UBERON:0010084 future diaphragm - + - + - + - + EHDAA2 - + PMID:23586979 - + PMID:23586979 @@ -455834,7 +455824,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -455843,7 +455833,7 @@ https://doi.org/10.1515/9783110264043 - + A sex cord that is part of a indifferent gonad. note that this represents the indifferent structure. EHDAA2:0004051 @@ -455853,7 +455843,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010141 primitive sex cord of indifferent gonad - + @@ -455862,20 +455852,20 @@ https://doi.org/10.1515/9783110264043 - + - + EHDAA2 - + EHDAA2 @@ -456086,7 +456076,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456104,14 +456094,14 @@ https://doi.org/10.1515/9783110264043 post-anal tail tip - + - + MA @@ -456387,7 +456377,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456404,7 +456394,7 @@ https://doi.org/10.1515/9783110264043 pair of dorsal aortae - + @@ -456417,7 +456407,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -456440,7 +456430,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456452,14 +456442,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010191 aortic system - + - + Wikipedia @@ -456642,7 +456632,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456660,14 +456650,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010227 future cardiac atrium - + - + ZFA @@ -456702,7 +456692,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456727,14 +456717,14 @@ https://doi.org/10.1515/9783110264043 eyeball of camera-type eye - + - + FMA @@ -456820,7 +456810,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456830,8 +456820,8 @@ https://doi.org/10.1515/9783110264043 - - + + @@ -456844,11 +456834,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0010252 1st arch mandibular mesenchyme from neural crest - + - + @@ -456861,13 +456851,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -456886,7 +456876,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456896,32 +456886,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme. EHDAA2:0000044 uberon UBERON:0010253 1st arch maxillary mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -456940,7 +456930,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -456951,8 +456941,8 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme. In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG] EHDAA2:0000098 @@ -456967,24 +456957,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0010256 4th arch mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -457025,7 +457015,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -457036,8 +457026,8 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme. EHDAA2:0004077 neural crest derived arch 6 mesenchyme @@ -457047,24 +457037,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0010257 6th arch mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -457091,7 +457081,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -457104,14 +457094,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010258 mesenchyme from rhombencephalic neural crest - + - + EHDAA2 @@ -457284,8 +457274,8 @@ https://doi.org/10.1515/9783110264043 - - + + Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. DHBA:12322 EFO:0003567 @@ -457299,11 +457289,11 @@ https://doi.org/10.1515/9783110264043 midbrain basal plate - + - + @@ -457316,13 +457306,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + ZFA @@ -457351,7 +457341,7 @@ https://doi.org/10.1515/9783110264043 - + Portion of neural tube that gives rise to the midbrain. we follow ZFA in temporally dividing midbrain NT from presumptive midbrain, but in future this may be collapsed TAO:0007039 @@ -457360,14 +457350,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010286 midbrain neural tube - + - + ZFA @@ -457384,20 +457374,20 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia:Sclera#Histology uberon UBERON:0010291 layer of sclera - + - + cjm @@ -457667,7 +457657,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -457683,14 +457673,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010312 immature eye - + - + definitional @@ -457942,20 +457932,20 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a limb/fin bud. uberon UBERON:0010329 paired limb/fin bud mesenchyme - + - + EHDAA2-abduced @@ -457990,20 +457980,20 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that is part of a extraembryonic membrane. uberon UBERON:0010333 extraembryonic membrane mesenchyme - + - + EHDAA2-abduced @@ -458022,7 +458012,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458032,32 +458022,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme. EHDAA2:0004601 uberon UBERON:0010334 maxillary process mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -458076,7 +458066,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458086,32 +458076,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme. EHDAA2:0004602 uberon UBERON:0010335 maxillary process mesenchyme from head mesenchyme - + - + - + EHDAA2 - + EHDAA2 @@ -458130,7 +458120,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458140,32 +458130,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme. EHDAA2:0004603 uberon UBERON:0010336 mandibular process mesenchyme from neural crest - + - + - + EHDAA2 - + EHDAA2 @@ -458184,7 +458174,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458194,32 +458184,32 @@ https://doi.org/10.1515/9783110264043 + - Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme. EHDAA2:0004604 uberon UBERON:0010337 mandibular process mesenchyme from head mesenchyme - + - + - + EHDAA2 - + EHDAA2 @@ -458238,7 +458228,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458248,21 +458238,21 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme. EHDAA2:0000043 uberon UBERON:0010338 1st arch maxillary mesenchyme from head mesenchyme - + - + EHDAA2 @@ -458281,7 +458271,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458291,21 +458281,21 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme. EHDAA2:0000036 uberon UBERON:0010339 1st arch mandibular mesenchyme from head mesenchyme - + - + EHDAA2 @@ -458324,7 +458314,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458335,7 +458325,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme. EMAPA:16130 mesenchyme derived from head mesoderm of mesenchyme of 1st arch @@ -458343,14 +458333,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010341 1st arch mesenchyme from head mesenchyme - + - + EMAPA @@ -458375,7 +458365,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458386,7 +458376,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme. EHDAA2:0000097 EMAPA:16771 @@ -458398,14 +458388,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010345 4th arch mesenchyme from head mesenchyme - + - + EHDAA2 @@ -458430,7 +458420,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458441,7 +458431,7 @@ https://doi.org/10.1515/9783110264043 - + Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme. EHDAA2:0004078 head mesenchyme derived arch 6 mesenchyme @@ -458451,14 +458441,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010347 6th arch mesenchyme from head mesenchyme - + - + EHDAA2 @@ -458825,7 +458815,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458840,14 +458830,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010375 pancreas dorsal primordium - + - + EHDAA2 @@ -458876,7 +458866,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458891,14 +458881,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010376 pancreas ventral primordium - + - + EHDAA2 @@ -458932,7 +458922,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -458946,7 +458936,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010377 mesenchyme from somatopleure - + @@ -458959,7 +458949,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -458992,7 +458982,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -459005,7 +458995,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010378 mesenchyme from splanchnopleure - + @@ -459018,7 +459008,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -459108,7 +459098,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -459129,14 +459119,14 @@ https://doi.org/10.1515/9783110264043 spleen trabecular artery - + - + MP @@ -459600,7 +459590,7 @@ https://doi.org/10.1515/9783110264043 - + Skeletal element that forms as a replacement or substitution of another element or tissue. VSAO:0000135 XAO:0004016 @@ -459609,7 +459599,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010522 replacement element - + @@ -459622,7 +459612,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -459641,7 +459631,7 @@ https://doi.org/10.1515/9783110264043 - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -459651,14 +459641,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010523 microcirculatory vessel - + - + ZFA @@ -459769,7 +459759,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -459793,14 +459783,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010531 metanephros induced blastemal cells - + - + EHDAA2 @@ -459848,7 +459838,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -459865,7 +459855,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010532 primitive nephron - + @@ -459878,7 +459868,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -459903,13 +459893,13 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -459922,14 +459912,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010533 metanephros cortex - + - + VHOG @@ -459998,7 +459988,7 @@ https://doi.org/10.1515/9783110264043 - + A primitive nephron that is part of a metanephros. primitive nephron EHDAA2:0001516 @@ -460008,14 +459998,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010535 primitive metanephric nephron - + - + EHDAA2 @@ -460037,7 +460027,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -460048,7 +460038,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010536 nephron progenitor - + @@ -460061,7 +460051,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -460550,7 +460540,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -460573,14 +460563,14 @@ https://doi.org/10.1515/9783110264043 bone of appendage girdle complex - + - + UBERONREF:0000003 @@ -460755,7 +460745,7 @@ https://doi.org/10.1515/9783110264043 - + Muscles of the pelvic girdle, hindlimb or pelvic fin. Muscles of the pelvic girdle, thigh, leg (crus), and foot (pes).[AAO] AAO:0000218 @@ -460773,14 +460763,14 @@ https://doi.org/10.1515/9783110264043 pelvic complex muscle - + - + prolog @@ -460848,7 +460838,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle of a pectoral girdle, pectoral fin or anterior limb. the MA class belongs here, based on its current child classes Muscles of the pectoral girdle, arm, forearm, and hand (brachium, antebrachium, manus respectively).[AAO] @@ -460865,14 +460855,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010891 pectoral complex muscle - + - + prolog @@ -460994,8 +460984,8 @@ https://doi.org/10.1515/9783110264043 - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO] FMA:23879 @@ -461008,11 +460998,11 @@ https://doi.org/10.1515/9783110264043 subdivision of skeleton - + - + @@ -461025,13 +461015,13 @@ https://doi.org/10.1515/9783110264043 - + UBERONREF:0000003 - + VSAO @@ -461070,7 +461060,7 @@ https://doi.org/10.1515/9783110264043 - + Skeletal element that forms around the notochord and is part of the vertebral column. we include a distinct subclass for bony vertebra In contrast to lampreys and jawed vertebrates, hagfishes were thought to lack vertebrae. Now, long overlooked vertebral rudiments have been analysed in hagfish, suggesting that vertebrae existed in the last common ancestor of all vertebrates.[well established][VHOG] @@ -461087,7 +461077,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0010913 vertebral element - + @@ -461101,7 +461091,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -461165,7 +461155,7 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of either the head or the neck. NCIT:C32716 UMLS:C0448281 @@ -461175,14 +461165,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0010959 craniocervical muscle - + - + prolog @@ -461207,12 +461197,12 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -461231,7 +461221,7 @@ https://doi.org/10.1515/9783110264043 pharyngeal arch cartilage - + @@ -461244,7 +461234,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -461288,7 +461278,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -461316,7 +461306,7 @@ https://doi.org/10.1515/9783110264043 palatoquadrate arch - + @@ -461329,7 +461319,7 @@ https://doi.org/10.1515/9783110264043 - + VHOG @@ -461882,7 +461872,7 @@ https://doi.org/10.1515/9783110264043 - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system @@ -461893,7 +461883,7 @@ https://doi.org/10.1515/9783110264043 postcranial axial skeletal system http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton - + @@ -461906,7 +461896,7 @@ https://doi.org/10.1515/9783110264043 - + cjm @@ -461930,7 +461920,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -461943,7 +461933,7 @@ https://doi.org/10.1515/9783110264043 - + Subdivision of urinary system which consists of the kidney and the ureters. FMA:45658 @@ -461956,24 +461946,24 @@ https://doi.org/10.1515/9783110264043 upper urinary tract - + - + - + FMA - + FMA-abduced-lr @@ -462006,7 +461996,7 @@ https://doi.org/10.1515/9783110264043 - + Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue. BTO:0003751 EMAPA:37970 @@ -462015,14 +462005,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011148 submucosal gland - + - + perforates @@ -462046,7 +462036,7 @@ https://doi.org/10.1515/9783110264043 - + Subdivision of skull that consists of the facial bones. EHDAA2:0002206 EHDAA:8361 @@ -462065,7 +462055,7 @@ https://doi.org/10.1515/9783110264043 facial skeleton http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg - + @@ -462078,7 +462068,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -462363,7 +462353,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a large intestine. FMA:15654 @@ -462377,14 +462367,14 @@ https://doi.org/10.1515/9783110264043 lamina propria of large intestine - + - + FMA @@ -462429,7 +462419,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle layer that is part of a large intestine. FMA:14971 NCIT:C32927 @@ -462442,14 +462432,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011198 muscle layer of large intestine - + - + FMA @@ -462507,7 +462497,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle layer that is part of a small intestine. FMA:14932 NCIT:C33569 @@ -462523,14 +462513,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011201 muscle layer of small intestine - + - + FMA @@ -462688,7 +462678,7 @@ https://doi.org/10.1515/9783110264043 - + Muscles within the eye (bulbus oculi).[AAO] AAO:0010038 EMAPA:18808 @@ -462699,14 +462689,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011222 intra-ocular muscle - + - + EMAPA @@ -462907,7 +462897,7 @@ https://doi.org/10.1515/9783110264043 - + The part of the trunk that is in the dorsum[cjm]. In humans, the subdivision of trunk which is demarcated from the trunk proper by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines, the external surface of the posterior abdominal wall; together with the trunk proper, it constitutes the trunk[FMA] EMAPA:35162 @@ -462922,7 +462912,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0011270 dorsal trunk - + @@ -462935,7 +462925,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -462971,8 +462961,8 @@ https://doi.org/10.1515/9783110264043 - - + + compare with 'stratum basale of epidermis'. This class is the source for many adult structures - see WP2062. See also: 'enveloping layer of ectoderm' EHDAA2:0001845 uberon @@ -462981,11 +462971,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0011272 embryonic skin basal layer - + - + @@ -462998,13 +462988,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -463186,7 +463176,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -463210,14 +463200,14 @@ https://doi.org/10.1515/9783110264043 lumen of esophagus - + - + FMA @@ -463331,7 +463321,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -463349,14 +463339,14 @@ https://doi.org/10.1515/9783110264043 paired limb/fin skeleton - + - + ISBN:9780878932504 @@ -463418,19 +463408,19 @@ https://doi.org/10.1515/9783110264043 - - + + EHDAA2:0002120 upper jaw future lip uberon UBERON:0011592 future upper lip - + - + @@ -463443,13 +463433,13 @@ https://doi.org/10.1515/9783110264043 - + fusion - + fusion @@ -463477,7 +463467,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -463498,14 +463488,14 @@ https://doi.org/10.1515/9783110264043 jaw region http://eol.org/collections/11578 - + - + EMAPA FMA-abduced ZFA-abduced @@ -463524,14 +463514,14 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0001020 lower jaw future lip uberon UBERON:0011596 future lower lip - + @@ -463544,7 +463534,7 @@ https://doi.org/10.1515/9783110264043 - + Wikipedia:Mandibular_prominence @@ -463621,14 +463611,14 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that develops_from a ectoderm and is part of a oral epithelium. EHDAA2:0004137 uberon UBERON:0011642 oral epithelium from ectoderm - + @@ -463641,7 +463631,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -464697,7 +464687,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle layer that is part of a wall of esophagus. In the upper esophagus, part of the externa is skeletal muscle, rather than smooth muscle FMA:62998 @@ -464711,14 +464701,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0011878 muscle layer of esophagus - + - + upper part Wikipedia:Muscular_layer @@ -464787,7 +464777,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -464829,7 +464819,7 @@ https://doi.org/10.1515/9783110264043 anterior uvea - + @@ -464842,7 +464832,7 @@ https://doi.org/10.1515/9783110264043 - + MP @@ -464883,7 +464873,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -464908,7 +464898,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0011899 epimysium - + @@ -464921,7 +464911,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -464974,7 +464964,7 @@ https://doi.org/10.1515/9783110264043 - + Masses of developing blood cells attached to endothelium in the yolk sac. EHDAA2:0000177 EMAPA:16115 @@ -464985,14 +464975,14 @@ https://doi.org/10.1515/9783110264043 yolk sac blood island - + - + EHDAA2 @@ -465022,8 +465012,8 @@ https://doi.org/10.1515/9783110264043 - - + + in EHDAA2 gives rise to connecting stalk blood vessels and extraembryonic umbilical vessels EHDAA2:0003242 blood island of umbilical vesicle @@ -465032,11 +465022,11 @@ https://doi.org/10.1515/9783110264043 UBERON:0011921 connecting stalk blood islands - + - + @@ -465049,13 +465039,13 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 - + EHDAA2 @@ -465747,7 +465737,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -465775,7 +465765,7 @@ https://doi.org/10.1515/9783110264043 urinary bladder vasculature - + @@ -465787,7 +465777,7 @@ https://doi.org/10.1515/9783110264043 - + EMAPA @@ -466325,7 +466315,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -466340,14 +466330,14 @@ https://doi.org/10.1515/9783110264043 We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts embryonic cloacal fold - + - + EHDAA2 @@ -466533,7 +466523,7 @@ https://doi.org/10.1515/9783110264043 - + The deep cervical artery (Profunda cervicalis) is an artery of the neck. FMA:10659 @@ -466545,14 +466535,14 @@ https://doi.org/10.1515/9783110264043 deep cervical artery - + - + FMA @@ -466781,20 +466771,20 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004588 uberon UBERON:0012361 internal anal region - + - + EHDAA2 @@ -466815,7 +466805,7 @@ https://doi.org/10.1515/9783110264043 - + A muscle layer that is part of an intestine. FMA:15697 intestinal muscularis propria @@ -466825,14 +466815,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0012367 muscle layer of intestine - + - + FMA @@ -466937,7 +466927,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -466962,14 +466952,14 @@ https://doi.org/10.1515/9783110264043 muscle layer of urinary bladder - + - + FMA @@ -467229,7 +467219,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -467251,7 +467241,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0012429 hematopoietic tissue - + @@ -467264,7 +467254,7 @@ https://doi.org/10.1515/9783110264043 - + defitional @@ -467410,7 +467400,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -467427,14 +467417,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0012463 cloacal lumen - + - + cjm @@ -467630,20 +467620,20 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004589 uberon UBERON:0012469 external anal region - + - + EHDAA2 @@ -467670,7 +467660,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -467690,14 +467680,14 @@ https://doi.org/10.1515/9783110264043 skeleton of pectoral complex - + - + FMA @@ -467766,7 +467756,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -467786,14 +467776,14 @@ https://doi.org/10.1515/9783110264043 skeleton of pelvic complex - + - + FMA @@ -467845,8 +467835,8 @@ https://doi.org/10.1515/9783110264043 - - + + The posterior region of the neck, including the suboccipital region. nuchal nape @@ -467869,11 +467859,11 @@ https://doi.org/10.1515/9783110264043 dorsal part of neck - + - + @@ -467886,13 +467876,13 @@ https://doi.org/10.1515/9783110264043 - + FMA - + FMA @@ -468851,7 +468841,7 @@ https://doi.org/10.1515/9783110264043 - + A vein that drains a lip. SCTID:367664002 labial vein of face @@ -468862,14 +468852,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013136 vein of lip - + - + FMA @@ -469212,12 +469202,12 @@ https://doi.org/10.1515/9783110264043 - + - + A future glans that is part of a male genital tubercle. EMAPA:29252 glans of male genital tubercle @@ -469225,14 +469215,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013239 future glans penis - + - + EMAPA @@ -469251,12 +469241,12 @@ https://doi.org/10.1515/9783110264043 - + - + A future glans that is part of a female genital tubercle. EMAPA:19170 glans of female genital tubercle @@ -469264,14 +469254,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013240 future glans clitoris - + - + EMAPA @@ -469287,7 +469277,7 @@ https://doi.org/10.1515/9783110264043 - + The precursor of the urethra. In humans, the urethral groove is a temporary linear indentation on the underside (ventral side) of the male penis during embryonic development. It typically appears around 8 weeks of gestation and becomes closed into a normal male urethra by the 12th week SCTID:361531004 @@ -469299,14 +469289,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013241 embryonic urethral groove - + - + Wikipedia @@ -469338,16 +469328,16 @@ https://doi.org/10.1515/9783110264043 - - + + - - + + An epithelial tube that develops from a Mullerian duct in a male. Later degenerates. consider separating the duct from the degenerating portion, as in EMAPA EHDAA2:0001052 @@ -469358,24 +469348,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0013247 male paramesonephric duct - + - + - + EHDAA2 - + EHDAA2 @@ -469408,7 +469398,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -469432,14 +469422,14 @@ https://doi.org/10.1515/9783110264043 cranial cavity http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg - + - + Wikipedia @@ -470018,7 +470008,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -470035,14 +470025,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013525 stomach lumen - + - + FMA @@ -470093,7 +470083,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of a intestinal villus. FMA:63587 intestinal villus epithelium @@ -470103,14 +470093,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0013636 epithelium of intestinal villus - + - + FMA @@ -471970,7 +471960,7 @@ https://doi.org/10.1515/9783110264043 - + An epithelium that is part of a frontonasal prominence. EHDAA2:0004108 EMAPA:32918 @@ -471978,7 +471968,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0014702 frontonasal process epithelium - + @@ -471991,7 +471981,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -472066,7 +472056,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -472081,14 +472071,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0014704 pleuroperitoneal canal lumen - + - + EHDAA2 @@ -472111,7 +472101,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0001147 EMAPA:17646 metanephros primitive collecting ducts @@ -472120,7 +472110,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0014706 primitive renal collecting duct system - + @@ -472133,7 +472123,7 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2 @@ -472635,20 +472625,20 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin). uberon UBERON:0014794 pectoral appendage muscle - + - + prolog @@ -472675,20 +472665,20 @@ https://doi.org/10.1515/9783110264043 - + Any muscle organ that is part of a pelvic appendage (hindlimb or pelvic fin). uberon UBERON:0014795 pelvic appendage muscle - + - + prolog @@ -472925,7 +472915,7 @@ https://doi.org/10.1515/9783110264043 - + One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites. Blood vessels that connect the dorsal aorta or the posterior cardinal vein and the dorsal longitudinal anastomotic vessel. They run along the vertical myotomal boundaries. At early stages these don't have venous or arterial markers[ZFA:0001285, ZFIN:ZDB-PUB-030908-4]. EFO:0003664 @@ -472943,7 +472933,7 @@ https://doi.org/10.1515/9783110264043 intersomitic vessel - + @@ -472956,7 +472946,7 @@ https://doi.org/10.1515/9783110264043 - + ZFA @@ -473183,7 +473173,7 @@ https://doi.org/10.1515/9783110264043 - + consider merging into myocardial compact layer FMA:83105 perimysial connective tissue of subepicardium @@ -473192,14 +473182,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0015128 subepicardial layer of epicardium - + - + FMA @@ -473299,7 +473289,7 @@ https://doi.org/10.1515/9783110264043 - + A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands. the only orbital gland found in anuran amphibians is either the Harderian or the lacrimal; if it is a lacrimal, then a progressive lateral migration of the lacrimal glands must occur through the amniotes[PMID:7559104] the only orbital gland found in anuran amphibians is the Harderian[PMID:8843648] @@ -473310,14 +473300,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0015152 gland of ocular region - + - + inferred @@ -473858,7 +473848,7 @@ https://doi.org/10.1515/9783110264043 - + A basement membrane of epithelium that is part of a respiratory system. EMAPA:37570 MA:0001815 @@ -473866,14 +473856,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0015329 respiratory system basement membrane - + - + MA @@ -474037,7 +474027,7 @@ https://doi.org/10.1515/9783110264043 - + The hepatic artery proper (also proper hepatic artery), arises from the common hepatic artery and runs alongside the portal vein and the common bile duct to form the portal triad. The hepatic artery proper gives off a small supraduodenal artery to the duodenal bulb. Then the right gastric artery comes off and runs to the left along the lesser curvature of the stomach to meet the left gastric artery, which is a branch of the celiac trunk. It subsequently gives off the cystic artery, which feeds the gallbladder, before bifurcating into the right and left hepatic arteries. Of note, the right and left hepatic arteries may demonstrate variant anatomy. A replaced right hepatic artery may arise from the superior mesenteric artery (SMA) and a replaced left hepatic artery may arise from the left gastric artery. EMAPA:37217 @@ -474052,7 +474042,7 @@ https://doi.org/10.1515/9783110264043 proper hepatic artery - + @@ -474065,7 +474055,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -474102,13 +474092,13 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -474128,14 +474118,14 @@ https://doi.org/10.1515/9783110264043 left hepatic artery - + - + FMA @@ -474180,13 +474170,13 @@ https://doi.org/10.1515/9783110264043 - + - + @@ -474206,14 +474196,14 @@ https://doi.org/10.1515/9783110264043 right hepatic artery - + - + FMA @@ -474622,7 +474612,7 @@ https://doi.org/10.1515/9783110264043 - + A lamina propria that is part of a duodenum. EMAPA:27255 @@ -474636,14 +474626,14 @@ https://doi.org/10.1515/9783110264043 duodenum lamina propria - + - + FMA @@ -475747,7 +475737,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -475770,7 +475760,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0016887 entire extraembryonic component - + @@ -475783,7 +475773,7 @@ https://doi.org/10.1515/9783110264043 - + AEO @@ -476609,7 +476599,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -476627,14 +476617,14 @@ https://doi.org/10.1515/9783110264043 skeletal musculature - + - + MA @@ -478109,7 +478099,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -478123,14 +478113,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0034710 spinal cord ventricular layer - + - + EHDAA2 @@ -479466,8 +479456,8 @@ https://doi.org/10.1515/9783110264043 - - + + The parietal pleura that lines the mediastinum. FMA:9736 NCIT:C94820 @@ -479481,24 +479471,24 @@ https://doi.org/10.1515/9783110264043 UBERON:0035431 mediastinal pleura - + - + - + FMA - + FMA @@ -479628,7 +479618,7 @@ https://doi.org/10.1515/9783110264043 - + Any of several arteries that arise from the aorta and supply blood to the esophagus. FMA:4149 @@ -479642,7 +479632,7 @@ https://doi.org/10.1515/9783110264043 esophageal artery - + @@ -479655,7 +479645,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -480263,7 +480253,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -480279,14 +480269,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0035763 cavity of cardiac chamber - + - + FMA @@ -480684,7 +480674,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -480700,14 +480690,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0035956 epididymal lumen - + - + FMA @@ -480815,20 +480805,20 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004070 uberon UBERON:0036072 respiratory primordium epithelium - + - + EHDAA2 @@ -480856,21 +480846,21 @@ https://doi.org/10.1515/9783110264043 - + EHDAA2:0004071 respiratory primordium associated mesenchyme uberon UBERON:0036073 respiratory primordium mesenchyme - + - + EHDAA2 @@ -481433,12 +481423,12 @@ https://doi.org/10.1515/9783110264043 - + - + Wall of ventricle which is continuous with the wall of aorta. FMA:9556 left ventricular wall @@ -481446,7 +481436,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0036285 wall of left ventricle - + @@ -481459,7 +481449,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -481484,12 +481474,12 @@ https://doi.org/10.1515/9783110264043 - + - + Wall of ventricle which is continuous with the wall of pulmonary trunk. FMA:9533 right ventricular wall @@ -481497,7 +481487,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0036286 wall of right ventricle - + @@ -481510,7 +481500,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -481543,7 +481533,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -481555,14 +481545,14 @@ https://doi.org/10.1515/9783110264043 UBERON:0036288 anterior wall of left ventricle - + - + FMA @@ -481709,7 +481699,7 @@ https://doi.org/10.1515/9783110264043 - + The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. NCIT:C54419 @@ -481720,14 +481710,14 @@ https://doi.org/10.1515/9783110264043 renal pelvis/ureter - + - + NCIT @@ -481831,27 +481821,27 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:14657 gallbladder wall uberon UBERON:0036343 wall of gallbladder - + - + FMA @@ -481870,19 +481860,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:15089 brachiocephalic arterial wall uberon UBERON:0036351 wall of brachiocephalic artery - + @@ -481895,7 +481885,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -481914,19 +481904,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:15090 subclavian arterial wall uberon UBERON:0036352 wall of subclavian artery - + @@ -481939,7 +481929,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -481958,7 +481948,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -481968,21 +481958,21 @@ https://doi.org/10.1515/9783110264043 - + FMA:15704 anal canal wall uberon UBERON:0036362 wall of anal canal - + - + FMA @@ -482001,19 +481991,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:15889 right ureteral wall uberon UBERON:0036375 wall of right ureter - + @@ -482026,7 +482016,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482045,12 +482035,12 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:15890 left ureteral wall @@ -482059,7 +482049,7 @@ https://doi.org/10.1515/9783110264043 wall of left ureter - + @@ -482072,7 +482062,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482091,19 +482081,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:18211 pulmonary arterial wall uberon UBERON:0036422 wall of pulmonary artery - + @@ -482116,7 +482106,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482135,14 +482125,14 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:18303 uterine tube wall wall of fallopian tube @@ -482151,7 +482141,7 @@ https://doi.org/10.1515/9783110264043 UBERON:0036441 wall of uterine tube - + @@ -482164,7 +482154,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482195,20 +482185,20 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:19779 urethral wall uberon UBERON:0036521 wall of urethra - + @@ -482221,7 +482211,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482240,19 +482230,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:231590 uberon UBERON:0036553 wall of synovial tendon sheath - + @@ -482265,7 +482255,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482278,20 +482268,20 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:58098 eyeball wall uberon UBERON:0036925 wall of eyeball - + @@ -482304,7 +482294,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482323,21 +482313,21 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:63144 orbit wall uberon UBERON:0037089 wall of orbit - + @@ -482350,7 +482340,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482369,19 +482359,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:66284 common carotid arterial wall uberon UBERON:0037094 wall of common carotid artery - + @@ -482394,7 +482384,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482413,7 +482403,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -482425,9 +482415,9 @@ https://doi.org/10.1515/9783110264043 - - - + + + Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees. FMA:7274 cardiac wall @@ -482435,15 +482425,15 @@ https://doi.org/10.1515/9783110264043 UBERON:0037144 wall of heart - + - + - + @@ -482456,19 +482446,19 @@ https://doi.org/10.1515/9783110264043 - + FMA - + FMA - + FMA @@ -482493,19 +482483,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:19676 male urethral wall uberon UBERON:0037447 wall of male urethra - + @@ -482518,7 +482508,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482537,19 +482527,19 @@ https://doi.org/10.1515/9783110264043 - + - + FMA:19780 female urethral wall uberon UBERON:0037455 wall of female urethra - + @@ -482562,7 +482552,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -482590,7 +482580,7 @@ https://doi.org/10.1515/9783110264043 - + @@ -482606,14 +482596,14 @@ https://doi.org/10.1515/9783110264043 https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + FMA Wikipedia @@ -482660,20 +482650,20 @@ https://doi.org/10.1515/9783110264043 - + FMA:15395 uberon UBERON:0039228 sigmoid vein - + - + FMA @@ -482790,21 +482780,21 @@ https://doi.org/10.1515/9783110264043 - + A vein that drains the urethra. FMA:21270 uberon UBERON:0039377 urethral vein - + - + FMA @@ -482837,14 +482827,14 @@ https://doi.org/10.1515/9783110264043 - + Ovarian vein, each instance of which is a tributary of some inferior vena cava that drains the right pampiniform plexus of some broad ligament. FMA:14342 uberon UBERON:0039856 right ovarian vein - + @@ -482857,7 +482847,7 @@ https://doi.org/10.1515/9783110264043 - + FMA @@ -484072,8 +484062,8 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - - + + A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles. Purkinje fibre network @@ -484081,11 +484071,11 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 UBERON:8000009 Purkinje fiber network - + - + @@ -484100,7 +484090,7 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + https://github.com/obophenotype/uberon/issues/1785 https://orcid.org/0000-0001-5208-3432 https://orcid.org/0000-0002-9791-0064 @@ -484108,7 +484098,7 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + https://github.com/obophenotype/uberon/issues/1785 https://orcid.org/0000-0001-5208-3432 https://orcid.org/0000-0002-9791-0064 @@ -486264,14 +486254,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + - + @@ -486285,14 +486275,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + PMID:16417468 - + @@ -486396,14 +486386,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + ZFS - + @@ -486432,14 +486422,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -486453,14 +486443,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -486489,14 +486479,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + vertebrates - + @@ -486675,14 +486665,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA-abduced-lr - + @@ -486696,14 +486686,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + definitional - + @@ -486717,14 +486707,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest - + @@ -486783,14 +486773,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + only in species that have a stomach - + @@ -486834,14 +486824,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Wikipedia:Vitelline_vein - + @@ -486900,14 +486890,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -486936,14 +486926,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Wikipedia:Vitelline_vein - + @@ -486957,15 +486947,15 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + may be present in other parts in other species FMA - + @@ -487054,15 +487044,15 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + right arch 4 in human embryology.ch - + @@ -487076,14 +487066,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487097,14 +487087,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Wikipedia:Vitelline_vein - + @@ -487118,14 +487108,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Wikipedia - + @@ -487139,14 +487129,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + PMID:22179203 - + @@ -487160,14 +487150,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487181,14 +487171,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487202,14 +487192,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487223,14 +487213,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487244,14 +487234,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487265,14 +487255,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487286,14 +487276,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487307,14 +487297,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487328,14 +487318,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487376,14 +487366,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487457,14 +487447,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest - + @@ -487478,14 +487468,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487499,14 +487489,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487520,14 +487510,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487558,14 +487548,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + cjm - + @@ -487611,14 +487601,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + PMID:16417468 - + @@ -487632,14 +487622,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + PMID:16417468 - + @@ -487653,14 +487643,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -487674,15 +487664,15 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + AAO https://github.com/geneontology/go-ontology/issues/16143 - + @@ -487696,14 +487686,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + ISBN:9780878932504 - + @@ -487732,14 +487722,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + teleosts - + @@ -487753,14 +487743,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + Mammals - + @@ -487774,14 +487764,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + conservatively place at deuterostome, excluding acoelomates - + @@ -487870,14 +487860,14 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + FMA - + @@ -492036,13 +492026,13 @@ http://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289 - + - + - + @@ -493500,9 +493490,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -493511,9 +493501,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -493545,9 +493535,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493556,9 +493546,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493590,9 +493580,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493601,9 +493591,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493635,9 +493625,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493646,9 +493636,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493680,9 +493670,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493691,9 +493681,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + - + @@ -493837,7 +493827,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493848,7 +493838,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493865,7 +493855,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493875,7 +493865,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493893,7 +493883,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493904,7 +493894,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493921,7 +493911,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -493931,7 +493921,7 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - + @@ -494080,9 +494070,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -494091,9 +494081,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -494168,9 +494158,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + @@ -494179,9 +494169,9 @@ e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase - - - + + + diff --git a/src/ontology/aism-edit.owl b/src/ontology/aism-edit.owl index 32ae799..c45bf33 100644 --- a/src/ontology/aism-edit.owl +++ b/src/ontology/aism-edit.owl @@ -2521,6 +2521,9 @@ + + + @@ -14528,9 +14531,9 @@ jgiron https://orcid.org/0000-0002-0851-6883 - + - + @@ -39756,7 +39759,7 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 obo:AISM_0000376 - The anatomical space adjacent to two cuticular punctures. + The distance between two cuticular punctures. @@ -39769,7 +39772,12 @@ gmontanaro https://orcid.org/0000-0003-0836-1364 obo:AISM_0000376 - Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 + Edited by jgiron https://orcid.org/0000-0002-0851-6883 +2024-05-11 +To make it a distance as opposed to an anatomical space and change 'adjacent to' for 'characteristic of' +Matching existing definitions e.g. http://purl.obolibrary.org/obo/AGRO_00000318 + +Former definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188 diff --git a/src/ontology/imports/bspo_import.owl b/src/ontology/imports/bspo_import.owl index 0ceab16..df4c7b6 100644 --- a/src/ontology/imports/bspo_import.owl +++ b/src/ontology/imports/bspo_import.owl @@ -7,9 +7,9 @@ Prefix(rdfs:=) Ontology( - + Annotation( ) -Annotation(owl:versionInfo "2024-03-16") +Annotation(owl:versionInfo "2024-05-11") Declaration(Class()) Declaration(Class()) diff --git a/src/ontology/imports/cl_import.owl b/src/ontology/imports/cl_import.owl index 0c548a6..98c21f3 100644 --- a/src/ontology/imports/cl_import.owl +++ b/src/ontology/imports/cl_import.owl @@ -7,9 +7,9 @@ Prefix(rdfs:=) Ontology( - -Annotation( ) -Annotation(owl:versionInfo "2024-03-16") + +Annotation( ) +Annotation(owl:versionInfo "2024-05-11") Declaration(Class()) Declaration(Class()) @@ -57,8 +57,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -76,20 +74,11 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty(rdfs:label)) Declaration(AnnotationProperty()) ############################ # Annotation Properties ############################ -# Annotation Property: (definition) - -AnnotationAssertion(rdfs:label "definition") - -# Annotation Property: (preferred_root) - -AnnotationAssertion(rdfs:label "preferred_root") - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -106,18 +95,6 @@ SubAnnotationPropertyOf( ) -# Annotation Property: (subset_property) - -AnnotationAssertion(rdfs:label "subset_property") - -# Annotation Property: (database_cross_reference) - -AnnotationAssertion(rdfs:label "database_cross_reference") - -# Annotation Property: (has_exact_synonym) - -AnnotationAssertion(rdfs:label "has_exact_synonym") - @@ -182,6 +159,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "secretory cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (cell of skeletal muscle) @@ -196,6 +175,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell of skeletal muscle") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (ectodermal cell) @@ -228,6 +209,7 @@ AnnotationAssertion( "epidermal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (endo-epithelial cell) @@ -247,6 +229,8 @@ AnnotationAssertion( AnnotationAssertion( "FMA:69074") AnnotationAssertion(rdfs:label "ecto-epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (general ecto-epithelial cell) @@ -265,6 +249,7 @@ AnnotationAssertion( AnnotationAssertion(rdfs:label "epithelial cell of alimentary canal") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (embryonic cell (metazoa)) @@ -286,6 +271,7 @@ AnnotationAssertion(Annotation( "CALOHA:TS-1277") "uterine tube glandular cell") AnnotationAssertion(rdfs:label "oviduct glandular cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) diff --git a/src/ontology/imports/iao_import.owl b/src/ontology/imports/iao_import.owl index 0586dba..3dd6195 100644 --- a/src/ontology/imports/iao_import.owl +++ b/src/ontology/imports/iao_import.owl @@ -7,9 +7,9 @@ Prefix(rdfs:=) Ontology( - + Annotation( ) -Annotation(owl:versionInfo "2024-03-16") +Annotation(owl:versionInfo "2024-05-11") Declaration(Class()) Declaration(Class()) diff --git a/src/ontology/imports/pato_import.owl b/src/ontology/imports/pato_import.owl index fef7268..53fe6fc 100644 --- a/src/ontology/imports/pato_import.owl +++ b/src/ontology/imports/pato_import.owl @@ -7,9 +7,9 @@ Prefix(rdfs:=) Ontology( - -Annotation( ) -Annotation(owl:versionInfo "2024-03-16") + +Annotation( ) +Annotation(owl:versionInfo "2024-05-11") Declaration(Class()) Declaration(Class()) @@ -209,6 +209,10 @@ SubAnnotationPropertyOf( "subset_property") +# Annotation Property: (creation date) + +AnnotationAssertion(rdfs:label "creation date") + # Annotation Property: (database_cross_reference) AnnotationAssertion(rdfs:label "database_cross_reference") @@ -221,6 +225,10 @@ AnnotationAssertion(rdfs:label "has_obo_namespace") +# Annotation Property: (id) + +AnnotationAssertion(rdfs:label "id") + ############################ # Object Properties diff --git a/src/ontology/imports/ro_import.owl b/src/ontology/imports/ro_import.owl index ea9f2a7..759654c 100644 --- a/src/ontology/imports/ro_import.owl +++ b/src/ontology/imports/ro_import.owl @@ -7,9 +7,9 @@ Prefix(rdfs:=) Ontology( - -Annotation( ) -Annotation(owl:versionInfo "2024-03-16") + +Annotation( ) +Annotation(owl:versionInfo "2024-05-11") Declaration(Class()) Declaration(Class()) @@ -415,7 +415,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "part of"@en) -AnnotationAssertion(rdfs:label "part of") AnnotationAssertion(rdfs:seeAlso ) AnnotationAssertion(rdfs:seeAlso ) AnnotationAssertion(rdfs:seeAlso "https://wiki.geneontology.org/Part_of"^^xsd:anyURI) @@ -442,7 +441,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "has part"@en) -AnnotationAssertion(rdfs:label "has part") SubObjectPropertyOf( ) TransitiveObjectProperty() @@ -498,8 +496,6 @@ AnnotationAssertion( "is bearer of"@en) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "has characteristic"@en) -AnnotationAssertion(rdfs:label "has characteristic") -AnnotationAssertion(rdfs:seeAlso "https://github.com/oborel/obo-relations/pull/284") InverseFunctionalObjectProperty() ObjectPropertyRange( ) @@ -527,9 +523,7 @@ AnnotationAssertion( "has_participant"@en) AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:has_participant") AnnotationAssertion(rdfs:label "has participant"@en) -AnnotationAssertion(rdfs:label "has participant") ObjectPropertyDomain( ) -ObjectPropertyDomain( ) ObjectPropertyRange( ) # Object Property: (function of) @@ -1243,7 +1237,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "enabled by"@en) -AnnotationAssertion(rdfs:label "enabled by") AnnotationAssertion(rdfs:seeAlso "https://wiki.geneontology.org/Enabled_by"^^xsd:anyURI) SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -1913,10 +1906,10 @@ ObjectPropertyRange( "A diagnostic testing device utilizes a specimen.") AnnotationAssertion( "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.") -AnnotationAssertion( ) -AnnotationAssertion( ) AnnotationAssertion( "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input.") AnnotationAssertion( "See github ticket https://github.com/oborel/obo-relations/issues/497") +AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion( "2021-11-08T12:00:00Z"^^xsd:dateTime) AnnotationAssertion( "utilizes") AnnotationAssertion(rdfs:label "device utilizes material"@en) @@ -1985,7 +1978,6 @@ AnnotationAssertion( "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t."@en) AnnotationAssertion(rdfs:label "process"@en) SubClassOf( ) -SubClassOf( ObjectAllValuesFrom( )) # Class: (disposition) @@ -2018,7 +2010,6 @@ AnnotationAssertion(rdfs:seeAlso "h AnnotationAssertion(rdfs:seeAlso "https://github.com/oborel/obo-relations/pull/284") SubClassOf( ) SubClassOf( ObjectAllValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) # Class: (role) @@ -2094,7 +2085,6 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "biological process"@en) AnnotationAssertion(rdfs:label "biological_process") SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kinase activity) @@ -2375,17 +2365,17 @@ DLSafeRule(Body(ObjectPropertyAtom( V DLSafeRule(Annotation(rdfs:comment "If a molecular function (X) has a regulatory subfunction, then any gene product which is an input to that subfunction has an activity that directly_regulates X. Note: this is intended for cases where the regaultory subfunction is protein binding, so it could be tightened with an additional clause to specify this.") Annotation(rdfs:label "inferring direct reg edge from input to regulatory subfunction") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) DLSafeRule(Annotation(rdfs:label "inferring direct neg reg edge from input to regulatory subfunction") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) DLSafeRule(Annotation(rdfs:label "inferring direct positive reg edge from input to regulatory subfunction") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Annotation(rdfs:label "effector input is compound function input") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Annotation(rdfs:label "Input of effector is input of its parent MF") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Annotation(rdfs:comment "if effector directly regulates X, its parent MF directly regulates X") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Annotation(rdfs:comment "if effector directly positively regulates X, its parent MF directly positively regulates X") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Annotation(rdfs:label "if effector directly negatively regulates X, its parent MF directly negatively regulates X") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Annotation(rdfs:label "'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ClassAtom(owl:Nothing Variable()) ClassAtom(owl:Nothing Variable()))) -DLSafeRule(Annotation(rdfs:label "'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ClassAtom(owl:Nothing Variable()) ClassAtom(owl:Nothing Variable()))) -DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Annotation(rdfs:label "effector input is compound function input") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Annotation(rdfs:label "Input of effector is input of its parent MF") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Annotation(rdfs:comment "if effector directly regulates X, its parent MF directly regulates X") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Annotation(rdfs:comment "if effector directly positively regulates X, its parent MF directly positively regulates X") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Annotation(rdfs:label "if effector directly negatively regulates X, its parent MF directly negatively regulates X") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Annotation(rdfs:label "'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ClassAtom(owl:Nothing Variable()) ClassAtom(owl:Nothing Variable()))) +DLSafeRule(Annotation(rdfs:label "'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ClassAtom(owl:Nothing Variable()) ClassAtom(owl:Nothing Variable()))) +DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) ) \ No newline at end of file diff --git a/src/ontology/reports/basic-report.tsv b/src/ontology/reports/basic-report.tsv index 87043e0..2567450 100644 --- a/src/ontology/reports/basic-report.tsv +++ b/src/ontology/reports/basic-report.tsv @@ -174,7 +174,7 @@ "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." "An epithelial cell found in the lining of the stomach." "FMA:62948" "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." - "The elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros in which the primordial germ cells become embedded, establishing it as the primordium of the testis or ovary." "EHDAA2:0004044 NCIT:C34321 FMA:321917 Wikipedia:Gonadal_ridge EFO:0001414 SCTID:361399001 NCIT:C34184 AAO:0011047 EMAPA:35899 UMLS:C1512243 UMLS:C0231047 SCTID:308801004 XAO:0000018 BTO:0001402" + "The elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros in which the primordial germ cells become embedded, establishing it as the primordium of the testis or ovary." "NCIT:C34321 EHDAA2:0004044 FMA:321917 Wikipedia:Gonadal_ridge EFO:0001414 SCTID:361399001 NCIT:C34184 AAO:0011047 EMAPA:35899 UMLS:C1512243 UMLS:C0231047 SCTID:308801004 XAO:0000018 BTO:0001402" "A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]." "FMA:13225 XAO:0004140 Wikipedia:Ventricular_outflow_tract" "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state." "The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity)." "NCIT:C12664 MESH:D034841 GAID:17 EFO:0000213 UMLS:C0230168 Wikipedia:Abdominal_cavity FMA:12266 SCTID:361294009 MA:0003057 galen:AbdominalCavity EMAPA:36505" @@ -449,7 +449,7 @@ "Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein." "Cell-cell signaling in which the ligand is carried between cells by an exosome." - "An endothelium that is part of an artery [Automatically generated definition]." "EMAPA:35148 VHOG:0001215 NCIT:C49194 BTO:0004757 AAO:0011013 UMLS:C1179025 XAO:0000357 MA:0000707 FMA:62116" + "An endothelium that is part of an artery [Automatically generated definition]." "EMAPA:35148 VHOG:0001215 BTO:0004757 NCIT:C49194 AAO:0011013 UMLS:C1179025 XAO:0000357 MA:0000707 FMA:62116" "The insect abdominal segment that is posterior to the insect abdominal segment IX and composed of abdominal tergite X and abdominal sternite X."@en "http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt:00000031" "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules." @@ -497,7 +497,7 @@ "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros." "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." - "Lip that covers the upper portion of the mouth.[TAO]." "VHOG:0001750 Wikipedia:Upper_lip ZFA:0005226 TAO:0001970 MA:0000919 FMA:59817 EMAPA:17925 SCTID:245776003" + "Lip that covers the upper portion of the mouth.[TAO]." "Wikipedia:Upper_lip VHOG:0001750 ZFA:0005226 TAO:0001970 MA:0000919 FMA:59817 EMAPA:17925 SCTID:245776003" "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve." "GC_ID:1" "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." @@ -532,7 +532,7 @@ "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." "BTO:0000249 FMA:66782 CALOHA:TS-0138" "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." "FMA:62511 BTO:0003687" "The cuticle of the segment of a hind leg attached to the distal margin of the metacoxa by the metacoxal-metatrochanteral conjunctiva and to the proximal margin of the metafemur by the metatrochantero-metafemoral conjunctiva."@en - "The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings." "VHOG:0001198 EHDAA2:0000257 EHDAA:2933 Wikipedia:Cloacal_membrane NCIT:C34128 UMLS:C0231056 EMAPA:16832 SCTID:308826008 EHDAA:214 FMA:295525" + "The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings." "VHOG:0001198 EHDAA2:0000257 EHDAA:2933 Wikipedia:Cloacal_membrane NCIT:C34128 UMLS:C0231056 EMAPA:16832 SCTID:308826008 FMA:295525 EHDAA:214" "Any process that modulates the frequency, rate or extent of colon smooth muscle contraction." "CALOHA:TS-1249" "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." @@ -865,7 +865,7 @@ "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." "The tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule." "Wikipedia:Canals_of_Hering SCTID:269922006 SCTID:227002 UMLS:C0227517 FMA:17545 MA:0002669 NCIT:C32255" "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." "KEGG:C00241" - "The stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum." "MA:0002560 EMAPA:17631 BTO:0001146 EHDAA:4860 UMLS:C0034196 VHOG:0000420 SCTID:362143006 NCIT:C12260 MESH:D011708 Wikipedia:Pylorus galen:Pylorus EHDAA2:0001580 FMA:14581 GAID:333" + "The stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum." "MA:0002560 EMAPA:17631 BTO:0001146 EHDAA:4860 UMLS:C0034196 VHOG:0000420 SCTID:362143006 NCIT:C12260 MESH:D011708 Wikipedia:Pylorus galen:Pylorus EHDAA2:0001580 GAID:333 FMA:14581" "A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell." "Any process that activates or increases the frequency, rate or extent of T cell differentiation." "The chemical reactions and pathways by which individual cells transform chemical substances." @@ -953,7 +953,7 @@ "A membranous sac in animals that serves as the receptacle of a liquid or contains gas." "BTO:0000123" "A portion of organism substance that is produced by exocrine glands." "EMAPA:36535 BTO:0002977 BTO:0002979 FMA:9675 galen:Secretion AEO:0001005 UMLS:C1516992 MA:0002504 MESH:D012634 NCIT:C34062" "The peritoneum responsible for connecting the jejunum and ileum (parts of the small intestine) to the back wall of the abdomen. Between the two sheets of peritoneum are blood vessels, lymph vessels, and nerves. This allows these parts of the small intestine to move relatively freely within the abdominopelvic cavity. The brain, however, cannot map sensation accurately, so sensation is usually referred to the midline, an example of referred pain[WP]." "MA:0001555 EMAPA:37745 SCTID:245456008 FMA:14643 Wikipedia:Mesentery#Mesentery_.28proper.29" - "Embryonic structure that develops into pancreatic bud." "ZFA:0000254 FMA:79792 EHDAA2:0001382 EFO:0003434 EHDAA:2163 EFO:0002579 TAO:0000254 EMAPA:17066 XAO:0001101" + "Embryonic structure that develops into pancreatic bud." "FMA:79792 ZFA:0000254 EHDAA2:0001382 EFO:0003434 EHDAA:2163 EFO:0002579 TAO:0000254 EMAPA:17066 XAO:0001101" "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." "Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels." "A tube in the kidney that collect and transport urine." "TAO:0005289 ZFA:0005289" @@ -1059,7 +1059,7 @@ "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." "The initial renal anlage that develops from the most rostral part of the nephrogenic cord is termed the pronephros." "GC_ID:1" - "Outer serosa layer of the uterus." "EMAPA:37792 MA:0001729 NCIT:C33298 FMA:17744 Wikipedia:Perimetrium SCTID:253705006 UMLS:C0227824" + "Outer serosa layer of the uterus." "UMLS:C0227824 EMAPA:37792 MA:0001729 NCIT:C33298 FMA:17744 Wikipedia:Perimetrium SCTID:253705006" "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." "Wikipedia:Cell_signaling" "The pampiniform plexus is a network of many small veins found in the male spermatic cord. It is formed by the union of multiple spermatic veins from the back of the testis and tributaries from the epididymis. The veins of the plexus ascend along the cord in front of the ductus deferens. Below the subcutaneous inguinal ring they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins. These again unite to form a single vein, the testicular vein, which opens on the right side into the inferior vena cava, at an acute angle, and on the left side into the left renal vein, at a right angle. The pampinoform plexus forms the chief mass of the cord. In addition to its function in venous return from the testes, the pampiniform plexus also plays a role in the temperature regulation of the testes. It acts as a heat exchanger, cooling blood in adjacent arteries. An abnormal enlargement of the pampiniform plexus is a medical condition called varicocele. [WP,unvetted]." "EMAPA:37385 FMA:19607 SCTID:279661001 Wikipedia:Pampiniform_venous_plexus MA:0001866" @@ -1113,7 +1113,7 @@ "The cranio-mandibular muscle that is attached to the gena and the insect mandible."@en "Enables the transfer of a macromolecule from one side of a membrane to the other." "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." - "Organism substance that is composed of sperm cells suspended in seminal fluid." "UMLS:C2756969 EMAPA:31488 MESH:D012661 NCIT:C13277 MA:0002522 GAID:1169 CALOHA:TS-0917 UMLS:C1518159 NCIT:C13713 BTO:0001230 FMA:62966 Wikipedia:Semen" + "Organism substance that is composed of sperm cells suspended in seminal fluid." "Wikipedia:Semen UMLS:C2756969 EMAPA:31488 MESH:D012661 NCIT:C13277 MA:0002522 GAID:1169 CALOHA:TS-0917 UMLS:C1518159 NCIT:C13713 BTO:0001230 FMA:62966" "GC_ID:1" "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." "A presumptive structure that has the potential to develop into a presomitic mesoderm." "EFO:0003421 ZFA:0000053 TAO:0000053" @@ -1304,7 +1304,7 @@ "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." - "Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated)." "Wikipedia:Syncytiotrophoblast FMA:83040 SCTID:256965005 NCIT:C33918 BTO:0001335 EHDAA:129 UMLS:C1135936 EMAPA:16068 EHDAA:91" + "Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated)." "Wikipedia:Syncytiotrophoblast FMA:83040 NCIT:C33918 SCTID:256965005 BTO:0001335 EHDAA:129 UMLS:C1135936 EMAPA:16068 EHDAA:91" "A cell that secretes glycosaminoglycans." "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." "Any collection of muscles that is part of a pelvic appendage." "TAO:0000258 ZFA:0000258" @@ -1671,7 +1671,7 @@ "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." "A coiling which is relatively high." "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." - "A spinal cord segment that adjacent_to a cervical region." "MA:0003081 SCTID:180960003 MESH:D066193 FMA:71166 neuronames:1654 BIRNLEX:1499 UMLS:C1278837 UMLS:C0581619 NCIT:C12892" + "A spinal cord segment that adjacent_to a cervical region." "SCTID:180960003 MA:0003081 MESH:D066193 FMA:71166 neuronames:1654 BIRNLEX:1499 UMLS:C1278837 UMLS:C0581619 NCIT:C12892" "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis." "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." "Subdivision of the skeletal system which consists of the axial skeleton plus associated joints." "FMA:7483" @@ -1709,7 +1709,7 @@ "An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc)." "VSAO:0000303 EMAPA:37854 FMA:24874" "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." "An epithelial cell of the kidney cortex." "KUPO:0001016" - "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." "Wikipedia:Cleavage_(embryo) BilaDO:0000006 ZFS:0000046 OGES:000020 MESH:D002970 BILS:0000107 XAO:1000004 PdumDv:0000200 OGES:000015 MmusDv:0000004 EFO:0001290 FBdv:00000054" + "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." "Wikipedia:Cleavage_(embryo) BilaDO:0000006 ZFS:0000046 OGES:000020 MESH:D002970 BILS:0000107 XAO:1000004 OGES:000015 PdumDv:0000200 MmusDv:0000004 EFO:0001290 FBdv:00000054" "Mesenchyme that is part of a pharyngeal arch 6." "FMA:318209 EMAPA:32765 EHDAA2:0004076" "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." "FMA:70567" "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." @@ -1737,7 +1737,7 @@ "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." "Wikipedia:Egg_activation" "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." "CALOHA:TS-0866 BTO:0001036 FMA:67748" - "The part of the retina that contains neurons and photoreceptor cells[GO]." "EMAPA:17171 EHDAA:4763 EHDAA2:0001253 AAO:0011095 MA:0000277 TAO:0000046 VHOG:0000535 FMA:58628 CALOHA:TS-0685 XAO:0003216 NCIT:C33166 EMAPA:18590 BTO:0000929 ZFA:0000046 UMLS:C1518263" + "The part of the retina that contains neurons and photoreceptor cells[GO]." "UMLS:C1518263 EMAPA:17171 EHDAA:4763 EHDAA2:0001253 AAO:0011095 MA:0000277 TAO:0000046 VHOG:0000535 FMA:58628 CALOHA:TS-0685 XAO:0003216 NCIT:C33166 EMAPA:18590 BTO:0000929 ZFA:0000046" "The dorsoventral thoracic muscle that extends between the profurca and the mesonotum."@en "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." @@ -2155,7 +2155,7 @@ "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." - "Enables the transfer of a protein from one side of a membrane to the other." "Reactome:R-HSA-184269 Reactome:R-HSA-9698930 Reactome:R-HSA-1299475 Reactome:R-HSA-5244404 Reactome:R-HSA-9636375 Reactome:R-HSA-5244428 Reactome:R-HSA-5336420 Reactome:R-HSA-5250616 Reactome:R-HSA-5246514 Reactome:R-HSA-5205661 Reactome:R-HSA-5250884 Reactome:R-HSA-5250972 Reactome:R-HSA-5210943 Reactome:R-HSA-5210947 Reactome:R-HSA-5229111 Reactome:R-HSA-3149434 Reactome:R-HSA-5228406 Reactome:R-HSA-5244506 Reactome:R-HSA-9698933 Reactome:R-HSA-1268022" + "Enables the transfer of a protein from one side of a membrane to the other." "Reactome:R-HSA-184269 Reactome:R-HSA-9698930 Reactome:R-HSA-1299475 Reactome:R-HSA-5244404 Reactome:R-HSA-9636375 Reactome:R-HSA-5244428 Reactome:R-HSA-5336420 Reactome:R-HSA-5250616 Reactome:R-HSA-5246514 Reactome:R-HSA-5205661 Reactome:R-HSA-5250884 Reactome:R-HSA-5210943 Reactome:R-HSA-5250972 Reactome:R-HSA-5210947 Reactome:R-HSA-5229111 Reactome:R-HSA-3149434 Reactome:R-HSA-5228406 Reactome:R-HSA-5244506 Reactome:R-HSA-9698933 Reactome:R-HSA-1268022" "The cuticular puncture that has a cuticular granule on its anterior margin."@en "The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum." "SCTID:261623000 VHOG:0000358 EMAPA:17024 EHDAA2:0001922 EHDAA:2999 MA:0001617" "Primordium that develops into the nervous system." "AAO:0000477" @@ -2293,7 +2293,7 @@ "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." - "The middle germ layer of the embryo, between the endoderm and ectoderm." "GAID:522 BTO:0000839 FBbt:00000126 EHDAA:124 FMA:69072 SCTID:362854004 AAO:0000304 EV:0100006 EHDAA:183 Wikipedia:Mesoderm MAT:0000174 EMAPA:16083 NCIT:C12750 ZFA:0000041 EFO:0001981 EHDAA2:0001128 VHOG:0000152 XAO:0000050 MIAA:0000174 EHDAA:160 CALOHA:TS-0623 TAO:0000041 MESH:D008648 UMLS:C0025485 BILA:0000037" + "The middle germ layer of the embryo, between the endoderm and ectoderm." "GAID:522 BTO:0000839 FBbt:00000126 EHDAA:124 FMA:69072 SCTID:362854004 AAO:0000304 EV:0100006 EHDAA:183 Wikipedia:Mesoderm MAT:0000174 EMAPA:16083 NCIT:C12750 ZFA:0000041 EFO:0001981 EHDAA2:0001128 XAO:0000050 VHOG:0000152 MIAA:0000174 EHDAA:160 CALOHA:TS-0623 TAO:0000041 MESH:D008648 UMLS:C0025485 BILA:0000037" "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." "The movement of a dendritic cell within or between different tissues and organs of the body." "A muscle of a pectoral girdle, pectoral fin or anterior limb." "AAO:0010687 FMA:9621 MA:0000615 EMAPA:32624" @@ -2397,7 +2397,7 @@ "BIRNLEX:2665 FMA:62420 SCTID:278748001 MA:0003080" "Any process that activates or increases the frequency, rate or extent of striated muscle development." "Any process that activates or increases the frequency, rate or extent of defense response to bacterium." - "A vein that returns blood from the intestines." "EHDAA:4442 NCIT:C53055 BTO:0002781 UMLS:C0025473 RETIRED_EHDAA2:0001125 MA:0002177 EMAPA:17348 MESH:D008642 Wikipedia:Mesenteric_vein SCTID:304045008" + "A vein that returns blood from the intestines." "EHDAA:4442 NCIT:C53055 BTO:0002781 UMLS:C0025473 RETIRED_EHDAA2:0001125 MA:0002177 MESH:D008642 EMAPA:17348 Wikipedia:Mesenteric_vein SCTID:304045008" "A brain that develops_from a neural tube." "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." @@ -2445,7 +2445,7 @@ "The infolding of a membrane." "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." "The epithelial layer that lines the luminal space of the esophagus." "UMLS:C1179544 CALOHA:TS-0698 BTO:0001578 EMAPA:16835 FMA:63063 EHDAA2:0001287 TAO:0001499 EFO:0003041 MA:0001565 ZFA:0001499 NCIT:C49221" - "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]." "FBbt:00005383 EMAPA:16255 EHDAA2:0001185 NCIT:C34210 SCTID:361410004 TGMA:0001036 Wikipedia:Midgut EHDAA:983 XAO:0000103 MA:0001564 BILA:0000086 UMLS:C0231052 BTO:0000863 VHOG:0000290 EFO:0001950 FMA:45617" + "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]." "FBbt:00005383 EMAPA:16255 EHDAA2:0001185 NCIT:C34210 SCTID:361410004 TGMA:0001036 EHDAA:983 Wikipedia:Midgut XAO:0000103 MA:0001564 BILA:0000086 UMLS:C0231052 BTO:0000863 VHOG:0000290 EFO:0001950 FMA:45617" "The cranio-hypopharyngeal muscle that is attached to the anterior tentorial arm and the suspensorium."@en "A shape quality inhering in a bearer by virtue of the bearer's being narrow, with the two opposite margins parallel." "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." @@ -2507,7 +2507,7 @@ "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney." "The hypopharyngeal sclerite on the proximal region of the hypopharynx."@en "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." - "A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage." "MA:0001906 XAO:0003084 FMA:54398 EMAPA:17910 AAO:0000274 TAO:0001273 EMAPA:17906 EHDAA:8005 EHDAA2:0004606 VHOG:0000428 ZFA:0001273" + "A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage." "ZFA:0001273 MA:0001906 XAO:0003084 FMA:54398 EMAPA:17910 AAO:0000274 TAO:0001273 EMAPA:17906 EHDAA:8005 EHDAA2:0004606 VHOG:0000428" "Any process that activates or increases the frequency, rate or extent of translational termination." "A CD14 molecule that is encoded in the genome of human." "UniProtKB:P08571" "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." @@ -2524,7 +2524,7 @@ "The movement of a T cell within or between different tissues and organs of the body." "The umbilical artery is a paired artery (with one for each half of the body) that is found in the abdominal and pelvic regions. In the fetus, it extends into the umbilical cord. [WP,unvetted]." "UMLS:C0041632 BTO:0000841 NCIT:C33827 EMAPA:16331 FMA:18820 Wikipedia:Umbilical_artery SCTID:261404000 EMAPA:16372 GAID:516 EHDAA:1026 EHDAA:410 MESH:D014469 CALOHA:TS-1077 MA:0002072 RETIRED_EHDAA2:0002106" "A cell of the seminiferous tubule epithelium." - "A gland that is part of a hemolymphoid system [Automatically generated definition]." "MA:0002962 EMAPA:18766" + "A gland that is part of a hemolymphoid system [Automatically generated definition]." "EMAPA:18766 MA:0002962" "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation." "An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column." "FMA:7155 BTO:0000420 Wikipedia:Neck UMLS:C0027530 AEO:0000108 galen:Neck NCIT:C13063 EHDAA2:0003108 SCTID:302550007 EFO:0000967 CALOHA:TS-2045 EMAPA:35587 MAT:0000297 MESH:D009333 MIAA:0000297 GAID:86 MA:0000024" @@ -2935,7 +2935,7 @@ "An ectoderm that is part of a buccopharyngeal membrane." "EMAPA:16260 EHDAA2:0000190" "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity." "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." - "Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax." "EMAPA:37234 SCTID:362666008 MA:0000028 FMA:24217" + "Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax." "SCTID:362666008 EMAPA:37234 MA:0000028 FMA:24217" "An endocardium that is part of a interventricular septum [Automatically generated definition]." "EHDAA2:0000887 VHOG:0000615 EHDAA2:0000886 FMA:83584" "Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." @@ -3084,7 +3084,6 @@ "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." "A ribosome contained within a subcellular membrane-bounded organelle." "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." - "The anatomical space adjacent to two cuticular punctures."@en "Mesenchyme that is part of a foregut-midgut junction." "EHDAA2:0000570 EMAPA:16364" "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." "Wikipedia:Biological_process" "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." "EMAPA:36497 UMLS:C0230139 Wikipedia:Thoracic_cavity MA:0000032 NCIT:C12905 SCTID:243949006 MESH:D035423 FMA:7565 GAID:93" @@ -3406,7 +3405,7 @@ "A cylindrical shape that is hollow." "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." "The arthropod foramen that is part of the foramen occipitale and located below the tentorial bridge."@en - "A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.." "UMLS:C0004600 galen:Back GAID:30 NCIT:C13062 MESH:D001415 EFO:0001405 CALOHA:TS-2223 Wikipedia:Dorsum_(anatomy) SCTID:123961009 FMA:14181 BTO:0001713" + "A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.." "UMLS:C0004600 GAID:30 galen:Back NCIT:C13062 MESH:D001415 EFO:0001405 CALOHA:TS-2223 Wikipedia:Dorsum_(anatomy) SCTID:123961009 FMA:14181 BTO:0001713" "A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]." "MA:0001578 EMAPA:37642" "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." "Wikipedia:Sexual_reproduction" "A portion of connective tissue that is part of a back [Automatically generated definition]." "EMAPA:37256 MA:0000495" @@ -3466,7 +3465,7 @@ "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." "A portal vein that transports nutrients from the digestive tract to the liver[Kardong]." "MA:0002132 VHOG:0000642 FMA:50735 Wikipedia:Hepatic_portal_vein TAO:0005090 AAO:0010214 ZFA:0005090" "The apophysis that is located ventromedially on the thorax and is connected to the coxa via muscles."@en - "A life cycle stage that starts with fertilization and ends with the fully formed embryo." "HsapDv:0000002 WBls:0000092 OGES:000022 OGES:000000 WBls:0000102 WBls:0000003 SCTID:296280003 FBdv:00005289 EV:0300001 FMA:72652 BilaDO:0000002 XAO:1000012 MmusDv:0000002" + "A life cycle stage that starts with fertilization and ends with the fully formed embryo." "HsapDv:0000002 WBls:0000092 OGES:000022 OGES:000000 WBls:0000102 WBls:0000003 SCTID:296280003 FBdv:00005289 FMA:72652 EV:0300001 BilaDO:0000002 XAO:1000012 MmusDv:0000002" "The sclerite on the ventral region of the metathorax that bears the metafurca and is attached to the metapleuro-metasternal conjunctiva."@en "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." "GC_ID:1" @@ -4141,7 +4140,7 @@ "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." "Reaxys:13246008 Patent:JP2008069152 CAS:25312-65-6" "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis." - "Dense regular connective tissue that connects muscle to bone[VSAO]." "Wikipedia:Tendon EHDAA2:0003091 GAID:276 UMLS:C0039508 MESH:D013710 SCTID:256667004 BTO:0001356 CALOHA:TS-1021 AEO:0000091 NCIT:C13045 MA:0000115 FMA:9721 EV:0100149 EMAPA:35854 ZFA:0005647 XAO:0000173 galen:Tendon VHOG:0001286 VSAO:0000073" + "Dense regular connective tissue that connects muscle to bone[VSAO]." "EHDAA2:0003091 GAID:276 UMLS:C0039508 MESH:D013710 SCTID:256667004 BTO:0001356 CALOHA:TS-1021 AEO:0000091 NCIT:C13045 MA:0000115 FMA:9721 EV:0100149 EMAPA:35854 ZFA:0005647 XAO:0000173 galen:Tendon VHOG:0001286 VSAO:0000073 Wikipedia:Tendon" "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization." "A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels." "Wikipedia:Pseudostratified_columnar_epithelium NCIT:C33419 UMLS:C1514590 FMA:45572 NCIT:C49316 UMLS:C0836138" @@ -4324,7 +4323,7 @@ "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process." "A lamina propria that is part of a mucosa of oral region." "EMAPA:26947" "A bone that is part of a cranium." "SCTID:181792001" - "An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]." "FMA:18930 MA:0001940 Wikipedia:Artery_to_the_ductus_deferens EMAPA:37513 SCTID:279659005" + "An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]." "FMA:18930 MA:0001940 Wikipedia:Artery_to_the_ductus_deferens SCTID:279659005 EMAPA:37513" "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles." "BTO:0004675 FMA:49187 XAO:0003173 SCTID:362618001 ZFA:0001414 MESH:D009778 neuronames:2431 TAO:0001414 AAO:0010199" "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." "A mucosa that is part of a duodenum [Automatically generated definition]." "MA:0003207 SCTID:362146003 EMAPA:27235 BTO:0000367 FMA:14942 CALOHA:TS-0213" @@ -4551,7 +4550,7 @@ "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." - "Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball." "TAO:0001410 BTO:0004687 ZFA:0001410 galen:Orbit FMA:53074 Wikipedia:Orbit_(anatomy) MESH:D009915 NCIT:C12347 GAID:223 UMLS:C0029180 MA:0002482 XAO:0003171" + "Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball." "TAO:0001410 BTO:0004687 ZFA:0001410 FMA:53074 galen:Orbit Wikipedia:Orbit_(anatomy) MESH:D009915 NCIT:C12347 GAID:223 UMLS:C0029180 MA:0002482 XAO:0003171" "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." "A transitional myocyte that is part of the interventricular septum." "FMA:263154" "A molecular entity that contains no carbon." @@ -4807,7 +4806,7 @@ "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." "MESH:D018485" "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." - "One of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO]." "EHDAA:5021 EHDAA:5915 SCTID:361529008 VHOG:0000540 Wikipedia:Metanephric_blastema EHDAA:4041 EHDAA2:0004062 EMAPA:17375" + "One of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO]." "EHDAA:5021 EHDAA:5915 SCTID:361529008 VHOG:0000540 Wikipedia:Metanephric_blastema EHDAA2:0004062 EHDAA:4041 EMAPA:17375" "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis." "A sulcus limitans of neural tube that is part of a future myelencephalon." "EHDAA2:0001945" "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." @@ -4851,7 +4850,7 @@ "FMA:83521" "The process in which the vasculature of the retina is generated and organized." "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." - "A gonad with both testicular and ovarian aspects[WP]." "WBbt:0005178 Wikipedia:Ovotestis BTO:0000981 MIAA:0000165 EFO:0000971 MAT:0000165" + "A gonad with both testicular and ovarian aspects[WP]." "WBbt:0005178 Wikipedia:Ovotestis MIAA:0000165 BTO:0000981 EFO:0000971 MAT:0000165" "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation." "An endothelium that is part of a capillary [Automatically generated definition]." "FMA:62114 EMAPA:36292 BTO:0004954 CALOHA:TS-0112 UMLS:C0006904 MA:0000711 NCIT:C49215" "The process in which the anatomical structures of the lateral mesoderm are generated and organized." @@ -4928,7 +4927,7 @@ "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." - "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." "FBdv:00005317 BilaDO:0000008 XAO:1000005 EFO:0001296 HsapDv:0000010 BILS:0000109 WBls:0000010 OGES:000019 MmusDv:0000013 ZFS:0000047 OGES:000004" + "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." "OGES:000004 FBdv:00005317 BilaDO:0000008 XAO:1000005 EFO:0001296 HsapDv:0000010 BILS:0000109 WBls:0000010 OGES:000019 MmusDv:0000013 ZFS:0000047" "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." "A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands." "EMAPA:17623 MA:0002784 FMA:63458 EMAPA:35814" @@ -5007,7 +5006,7 @@ "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." "The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts." "BTO:0001513" "The region of cuticle on the lateral region of the insect thorax that is attached to the notum and the sternum and is attached to the coxae by skeletal muscle tissue and the basal coxal conjunctiva."@en - "That part of the spine comprising the thoracic vertebrae." "AAO:0000612 EHDAA:5063 SCTID:243931006 EMAPA:17396 MA:0003155 NCIT:C69315 UMLS:C0581269 BTO:0004150 FMA:9140" + "That part of the spine comprising the thoracic vertebrae." "AAO:0000612 SCTID:243931006 EHDAA:5063 EMAPA:17396 MA:0003155 NCIT:C69315 UMLS:C0581269 BTO:0004150 FMA:9140" "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process." "The region of cuticle of the postabdomen that is distal to the genital chamber."@en "Any process that activates or increases the frequency, rate or extent of oxygen metabolic process." @@ -5039,7 +5038,7 @@ "Any process that modulates the frequency, rate or extent of leukocyte differentiation." "A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]." "MA:0000704 EMAPA:36503" "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." "CAS:63231-63-0" - "A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]." "UMLS:C0014259 SCTID:368827009 NCIT:C12707 ZFA:0001687 FMA:63882 MA:0001242 EMAPA:35935 GAID:891 TAO:0002186 Wikipedia:Corneal_endothelium MESH:D004728 CALOHA:TS-0172" + "A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]." "UMLS:C0014259 NCIT:C12707 SCTID:368827009 ZFA:0001687 FMA:63882 MA:0001242 EMAPA:35935 GAID:891 TAO:0002186 Wikipedia:Corneal_endothelium MESH:D004728 CALOHA:TS-0172" "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." "Muscle contraction of cardiac muscle tissue." @@ -5240,7 +5239,7 @@ "The conjunctiva that is part of the antenna, is encircled by the flagellomere 8 and encircles the flagellomere 9."@en "The morphogenesis of trophectoderm cells." "A simple monocarboxylic acid containing two carbons." "PMID:16774200 MetaCyc:ACET PDBeChem:ACT PMID:22173419 Gmelin:1380 Wikipedia:Acetic_acid PMID:16630552 PMID:22153255 LIPID_MAPS_instance:LMFA01010002 PMID:19416101 KEGG:C00033 HMDB:HMDB0000042 KNApSAcK:C00001176 PMID:19469536 PMID:15107950 PMID:17190852 Drug_Central:4211 CAS:64-19-7 PMID:12005138 Beilstein:506007 Reaxys:506007 PDBeChem:ACY KEGG:D00010 PPDB:1333" - "Embryonic ectoderm that gives rise to nervous tissue." "ZFA:0001120 FMA:87657 EHDAA:1498 BILA:0000039 NCIT:C34228 CALOHA:TS-1212 EHDAA:255 EMAPA:16073 TAO:0001120 XAO:0000042 AAO:0011074 UMLS:C1518271 FBbt:00001057 MAT:0000176 MIAA:0000176 VHOG:0000150 EV:0100004 Wikipedia:Neuroectoderm EHDAA2:0001248" + "Embryonic ectoderm that gives rise to nervous tissue." "ZFA:0001120 FMA:87657 EHDAA:1498 BILA:0000039 NCIT:C34228 CALOHA:TS-1212 EHDAA:255 EMAPA:16073 TAO:0001120 XAO:0000042 UMLS:C1518271 AAO:0011074 FBbt:00001057 MAT:0000176 MIAA:0000176 VHOG:0000150 EV:0100004 Wikipedia:Neuroectoderm EHDAA2:0001248" "Any apoptotic process in a hepatocyte, the main structural component of the liver." "A CD4 molecule that is encoded in the genome of human." "UniProtKB:P01730" "Anatomical system that consists of all the joints of the body." "FMA:23878 VSAO:0000181 EMAPA:35150 MA:0003007 SCTID:361827000" @@ -5315,7 +5314,7 @@ "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." "BTO:0000725 CALOHA:TS-0448" "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." - "The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]." "UMLS:C1516496 FMA:76621 NCIT:C34121 AAO:0010153 XAO:0003059 Wikipedia:Chondrocranium SCTID:155540009 AAO:0000094 EHDAA:6031" + "The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]." "FMA:76621 UMLS:C1516496 NCIT:C34121 AAO:0010153 XAO:0003059 Wikipedia:Chondrocranium SCTID:155540009 AAO:0000094 EHDAA:6031" "The conjunctiva of the insect maxilla that connects the clypeus and the labrum."@en "KUPO:0001116" "GC_ID:1" @@ -5378,7 +5377,7 @@ "A sphincter muscle that is part of a cloaca." "NCIT:C34129 UMLS:C1516658" "The sclerite of the notum that is attached to the anterior margin of the scutum."@en "The insect abdomen that has abdominal sternites 1-8 and does not have abdominal sternite 9."@en - "Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle." "Wikipedia:Embryonic_ventricle SCTID:361524003 NCIT:C34160 EMAPA:16350 ZFA:0001719 FMA:71006 EHDAA2:0001531 TAO:0002231" + "Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle." "SCTID:361524003 Wikipedia:Embryonic_ventricle NCIT:C34160 EMAPA:16350 ZFA:0001719 FMA:71006 EHDAA2:0001531 TAO:0002231" "A mucosa that is part of a rectum [Automatically generated definition]." "FMA:15033 CALOHA:TS-2107 EMAPA:27081 MA:0003218 SCTID:362167003" "The part of the sternum that is attached to the anterior margin of the basisternum."@en "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." @@ -5662,7 +5661,7 @@ "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." "Any process that modulates the frequency, rate or extent of neuroinflammatory response." "A region of the stomach that is lined with glandular epithelium." "EMAPA:17623 UMLS:C0227197 NCIT:C77661 MA:0001613 SCTID:27633001" - "Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present." "EFO:0000966 ZFA:0001115 MA:0000004 galen:Trunk BTO:0001493 BILA:0000116 NCIT:C33816 CALOHA:TS-1071 XAO:0000054 SCTID:262225004 AAO:0010339 MIAA:0000296 Wikipedia:Torso XAO:0003025 FMA:7181 EMAPA:31857 TAO:0001115 MAT:0000296 UMLS:C0460005" + "Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present." "EFO:0000966 ZFA:0001115 MA:0000004 galen:Trunk BTO:0001493 BILA:0000116 NCIT:C33816 CALOHA:TS-1071 XAO:0000054 SCTID:262225004 AAO:0010339 MIAA:0000296 Wikipedia:Torso XAO:0003025 EMAPA:31857 FMA:7181 TAO:0001115 MAT:0000296 UMLS:C0460005" "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." @@ -5799,7 +5798,7 @@ "A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]." "EMAPA:17320 EHDAA2:0004154 FMA:7285 SCTID:189936008 VHOG:0001225" "A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]." "BTO:0001338 CALOHA:TS-0998 FMA:66762" "A muscular coat that is part of a colon." "FMA:14986 EMAPA:27383 SCTID:362158003 MA:0003198" - "A head mesenchyme that develops_from a mesoderm." "AAO:0011051 VHOG:0000185 EHDAA2:0001118 EFO:0003337 EMAPA_RETIRED:16270 TAO:0000998 FMA:293859 XAO:0000053 EFO:0003603 ZFA:0000998 EHDAA:655 EMAPA:16099" + "A head mesenchyme that develops_from a mesoderm." "AAO:0011051 VHOG:0000185 EHDAA2:0001118 EFO:0003337 EMAPA_RETIRED:16270 TAO:0000998 FMA:293859 XAO:0000053 ZFA:0000998 EFO:0003603 EHDAA:655 EMAPA:16099" "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." @@ -5842,7 +5841,7 @@ "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." "The sclerite attached to the spinasternum."@en "The sclerite of the labium that is anteriorly attached to the mentum by the submental-mental conjunctiva."@en - "An epithelial tube that is part of the nephron, the functional part of the kidney." "NCIT:C49274 CALOHA:TS-1262 FMA:15627 EMAPA:27782 TAO:0001287 UMLS:C0022674 EV:0100387 MA:0000377 MESH:D007684 GAID:433 ZFA:0001287 BTO:0000343 Wikipedia:Renal_tubule SCTID:361332007 EFO:0003666" + "An epithelial tube that is part of the nephron, the functional part of the kidney." "NCIT:C49274 FMA:15627 CALOHA:TS-1262 EMAPA:27782 TAO:0001287 UMLS:C0022674 EV:0100387 MA:0000377 MESH:D007684 GAID:433 ZFA:0001287 BTO:0000343 Wikipedia:Renal_tubule SCTID:361332007 EFO:0003666" "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." "A one dimensional, immaterial anatomical entity." "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." @@ -6313,7 +6312,7 @@ "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." "The process in which the anatomical structures of the liver are generated and organized." - "The outermost layer of a blood vessel, composed mainly of fibrous tissue." "EMAPA:36299 NCIT:C33818 UMLS:C0225342 SCTID:61066005 Wikipedia:Tunica_externa_(vessels) BTO:0002010" + "The outermost layer of a blood vessel, composed mainly of fibrous tissue." "EMAPA:36299 UMLS:C0225342 NCIT:C33818 SCTID:61066005 Wikipedia:Tunica_externa_(vessels) BTO:0002010" "One of the three blood vessels, usually one large umbilical vein and two small umbilical arteries, buried within Wharton's jelly, that transport blood to and from the placenta, where exchange between the mother and fetus takes place; the umbilical vein carries oxygenated, nutrient-rich blood from the placenta to the fetus, and the umbilical arteries carry deoxygenated, nutrient-depleted blood from the fetus to the placenta." "EMAPA:36493 SCTID:408728001" "A neural crest that has_potential_to_developmentally_contribute_to a spinal cord." "VHOG:0001006 EMAPA:16881 EHDAA:696 EMAPA:16163" "The cuticle of the flagellomere that is distal to the flagellomere 1 and is encircled by the flagellomere 1-flagellomere 2 conjunctiva."@en @@ -6481,11 +6480,11 @@ "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus." "A mucosa that is part of a lower lip [Automatically generated definition]." "NCIT:C12225 UMLS:C0226939 SCTID:362089001 FMA:59833" "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." - "Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells." "TAO:0000113 FMA:76622 EHDAA2:0000732 EMAPA_RETIRED:16269 ZFA:0000113 EHDAA:179 EMAPA:16098 EFO:0003492 VHOG:0000332" + "Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells." "FMA:76622 EHDAA2:0000732 EMAPA_RETIRED:16269 ZFA:0000113 EHDAA:179 EMAPA:16098 EFO:0003492 VHOG:0000332 TAO:0000113" "An extraembryonic structure that develops_from a syncytiotrophoblast and is part of a chorion." "EHDAA:156 EHDAA2:0001973" "A muscular coat that is part of a seminal vesicle [Automatically generated definition]." "MA:0002913 FMA:19404 EMAPA:29773" "An integrin alpha-M that is encoded in the genome of human." "UniProtKB:P11215" - "A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]." "FMA:72025 EMAPA:35323 MA:0001573" + "A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]." "FMA:72025 MA:0001573 EMAPA:35323" "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." "FMA:15889" "The conjunctiva of the postabdomen that joins the abdominal tergite X and each paraproct."@en @@ -6718,6 +6717,7 @@ "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." "The process in which the anatomical structures of the right ventricular myocardium are generated and organized." "GC_ID:1" + "The distance between two cuticular punctures."@en "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." "A protein coding gene resilin in fruit fly." @@ -6728,7 +6728,7 @@ "Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]." "VHOG:0000118 UMLS:C1517749 EHDAA2:0000919 AAO:0010574 ZFA:0000121 SCTID:361477005 FMA:293149 EHDAA:379 XAO:0000311 TAO:0000121 EMAPA:16179 NCIT:C34199 Wikipedia:Lateral_plate_mesoderm" "A zone of skin that is part of a craniocervical region." "NCIT:C12294 UMLS:C1522650 MA:0000574 EMAPA:37276" "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." - "A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]." "BTO:0001660 EMAPA:35734 MA:0001830" + "A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]." "MA:0001830 BTO:0001660 EMAPA:35734" "The portion of the plasma membrane surrounding a cilium." "The conjunctiva of the labium that connects the prementum and the glossa."@en "Any organ component layer that consists of smooth muscle tissue." @@ -6758,7 +6758,7 @@ "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." "A myocardial endocrine cell that is part of the atrium." "FMA:83389" - "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." "EHDAA:5029 EHDAA2:0004060 SCTID:50961009 VHOG:0000414 EHDAA:5919 UMLS:C0231057 Wikipedia:Definitive_urogenital_sinus NCIT:C34322 EMAPA:17379" + "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." "EHDAA:5029 EHDAA2:0004060 SCTID:50961009 VHOG:0000414 EHDAA:5919 UMLS:C0231057 Wikipedia:Definitive_urogenital_sinus EMAPA:17379 NCIT:C34322" "The disaggregation of an organelle into its constituent components." "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." "Reactome:R-HSA-374896 Reactome:R-HSA-374919" "GC_ID:1" @@ -6826,7 +6826,7 @@ "The conjunctiva of the insect abdomen that connects the abdominal sternite III and the abdominal sternite IV."@en "Any process that activates or increases the frequency, rate or extent of lipid localization." "A membrane that is a (regional) part of the plasma membrane." - "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm." "UMLS:C1708239 VHOG:0001223 Wikipedia:Germ_layer NCIT:C12950 GAID:1303 BTO:0000556 FMA:69069 UMLS:C0920502 XAO:0003011 FBbt:00000110 MESH:D005855 EMAPA:36033 AAO:0000480 ZFA:0001122 TAO:0001122 NCIT:C54105 BILA:0000035" + "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm." "UMLS:C1708239 VHOG:0001223 Wikipedia:Germ_layer NCIT:C12950 GAID:1303 BTO:0000556 FMA:69069 UMLS:C0920502 FBbt:00000110 XAO:0003011 MESH:D005855 EMAPA:36033 AAO:0000480 ZFA:0001122 TAO:0001122 NCIT:C54105 BILA:0000035" "A neural cell adhesion molecule 1 that is encoded in the genome of mouse." "UniProtKB:P13595" "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere I and encircles mesotarsomere II."@en @@ -6937,7 +6937,7 @@ "SCTID:255782009 FMA:72173" "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage." - "Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree)." "Wikipedia:Biliary_system SCTID:361354009 GAID:279 NCIT:C12678 FMA:79646 MESH:D001659 MA:0001273" + "Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree)." "Wikipedia:Biliary_system SCTID:361354009 NCIT:C12678 GAID:279 FMA:79646 MESH:D001659 MA:0001273" "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." "A mesentery that is part of a uterus [Automatically generated definition]." "FMA:19816 EMAPA:35562 Wikipedia:Mesometrium MA:0002931 SCTID:250172001" "A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]." "BTO:0002501 FMA:85273 Wikipedia:Trabecula" @@ -6956,7 +6956,7 @@ "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." "The cuticular depression that corresponds to an apophysis."@en - "The tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct." "EMAPA:16841 SCTID:245398005 UMLS:C0010672 MA:0000355 EHDAA2:0000333 TAO:0005166 NCIT:C32421 EHDAA:3045 Wikipedia:Cystic_duct MESH:D003549 GAID:290 VHOG:0000213 galen:CysticDuct ZFA:0005166 FMA:14539" + "The tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct." "EMAPA:16841 SCTID:245398005 MA:0000355 EHDAA2:0000333 UMLS:C0010672 TAO:0005166 NCIT:C32421 EHDAA:3045 Wikipedia:Cystic_duct MESH:D003549 GAID:290 VHOG:0000213 galen:CysticDuct ZFA:0005166 FMA:14539" "The convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery." "GAID:471 EHDAA2:0000132 MA:0000475 Wikipedia:Arch_of_aorta EFO:0002526 SCTID:181300001 FMA:3768 EMAPA:17613 BTO:0000157 VHOG:0001196" "The conjunctiva of the insect abdomen that connects the abdominal sternite I and the abdominal sternite II."@en "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." @@ -7250,7 +7250,7 @@ "GC_ID:1" "GC_ID:1" "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." - "The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm." "EHDAA2:0001968 EHDAA:7860 EHDAA:4790 FMA:87656 EHDAA:1494 Wikipedia:External_ectoderm NCIT:C34309 EHDAA:4796 BTO:0006242 EHDAA:4784 UMLS:C1515087 EMAPA:16096 EHDAA:350" + "The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm." "EHDAA:350 EHDAA2:0001968 EHDAA:7860 EHDAA:4790 FMA:87656 EHDAA:1494 Wikipedia:External_ectoderm NCIT:C34309 EHDAA:4796 BTO:0006242 EHDAA:4784 UMLS:C1515087 EMAPA:16096" "An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions." "VSAO:0000305 galen:ShoulderGirdle FMA:23217 SCTID:229759004 EMAPA:37856" "The vessels formed within the sixth pair of branchial arches in embryogenesis." "AAO:0010422 EHDAA2:0000102 ZFA:0005016 SCTID:308779008 XAO:0000353 Wikipedia:Aortic_arches#Arch_6 TAO:0005016 VHOG:0000144 EMAPA:17005" "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." @@ -7498,7 +7498,7 @@ "A portal system that begins in capillaries in the wall of the digestive tract and and runs as the hepatic portal vein to the liver." "AAO:0010225" "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." "FMA:83673" - "The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." "ZFA:0000014 Wikipedia:Dorsal_aorta EHDAA:402 XAO:0000051 EMAPA:18606 VHOG:0000264 TAO:0000014 BTO:0004673 SCTID:338637006 AAO:0011029" + "The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." "Wikipedia:Dorsal_aorta EHDAA:402 XAO:0000051 EMAPA:18606 VHOG:0000264 TAO:0000014 BTO:0004673 SCTID:338637006 AAO:0011029 ZFA:0000014" "Any process that modulates the frequency, rate or extent of angiogenesis." "A cell specialized to detect and transduce light." "CALOHA:TS-0868 FMA:86740 BTO:0001060" @@ -7923,7 +7923,7 @@ "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." "An apical ectodermal ridge that is part of a pelvic appendage bud." "VHOG:0001066 ZFA:0001385 EMAPA:16892 EHDAA2:0003194 EFO:0003681 TAO:0001385" "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." - "Major subdivision of an organism that protrudes from the body[DOS, CARO]." "EFO:0000799 BTO:0001492 VSAO:0000075 FBbt:00007000 EHDAA2:0003193 EMAPA:37283 UMLS:C0598782 NCIT:C61460 XAO:0000218 MESH:D005121 Wikipedia:Appendage EV:0100155 HAO:0000144 AEO:0000193 MIAA:0000023 BILA:0000018 MAT:0000023 CARO:0010003" + "Major subdivision of an organism that protrudes from the body[DOS, CARO]." "EFO:0000799 BTO:0001492 VSAO:0000075 FBbt:00007000 EHDAA2:0003193 EMAPA:37283 UMLS:C0598782 NCIT:C61460 MESH:D005121 XAO:0000218 Wikipedia:Appendage EV:0100155 HAO:0000144 AEO:0000193 MIAA:0000023 BILA:0000018 MAT:0000023 CARO:0010003" "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." "GC_ID:1" "A stroma that is part of a liver." "FMA:17553" @@ -7931,7 +7931,7 @@ "Any process that modulates the occurrence or rate of T cell death by apoptotic process." "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." "The cuticle of the paired appendage of the prothorax that is anterior to the cuticle of a mid leg and composed of cuticle of procoxa, cuticle of protrochanter, cuticle of profemur, cuticle of protibia, cuticle of protarsus, and cuticle of propretarsus."@en - "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." "NCIT:C13236 HAO:0000004 XAO:0004001 AEO:0000004 TAO:0001487 BILA:0000004 FBbt:00007019 ZFA:0001487 AAO:0010839 CALOHA:TS-2101 VHOG:0001726 TGMA:0001824 SPD:0000008 MA:0002450 CARO:0000004 galen:BodySubstance FMA:9669 EHDAA2:0003004 EMAPA:35178" + "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." "NCIT:C13236 HAO:0000004 XAO:0004001 TAO:0001487 AEO:0000004 BILA:0000004 FBbt:00007019 ZFA:0001487 AAO:0010839 CALOHA:TS-2101 VHOG:0001726 TGMA:0001824 SPD:0000008 MA:0002450 CARO:0000004 galen:BodySubstance FMA:9669 EHDAA2:0003004 EMAPA:35178" "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." "Reactome:R-HSA-9794270 Reactome:R-HSA-2161500 Reactome:R-HSA-9794523 Reactome:R-HSA-549304 Reactome:R-HSA-549279 Reactome:R-HSA-561054 Reactome:R-HSA-9795207 Reactome:R-HSA-549129 Reactome:R-HSA-561072 Reactome:R-HSA-549322" "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." diff --git a/src/ontology/reports/edges.tsv b/src/ontology/reports/edges.tsv index 5d7e762..d8dd297 100644 --- a/src/ontology/reports/edges.tsv +++ b/src/ontology/reports/edges.tsv @@ -1,12820 +1,12824 @@ ?x ?p ?y - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + - - _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid38439 - - - - - - - - - - - - - - - - - - - - - + + + + + + + +_:B57bd6b9aX2D9909X2D49b0X2Daed0X2Dc0391c742955genid61220 + + + + + + + + + + + + + + + + + + + + + + + + + +_:B57bd6b9aX2D9909X2D49b0X2Daed0X2Dc0391c742955genid60905 + + + + + + + + + + + + + + + + + + + + + + + + + +_:B57bd6b9aX2D9909X2D49b0X2Daed0X2Dc0391c742955genid61390 + + + + + + + + + + + + + + + + + + + + + + + + + _:B57bd6b9aX2D9909X2D49b0X2Daed0X2Dc0391c742955genid15312 + + + + + + + + + + + - 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_:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6825 - - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6443 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid343 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6686 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6704 + - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid3641 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid1955 @@ -25543,6 +25533,7 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2826 @@ -25551,26 +25542,28 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 - - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid2744 + + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid1955 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid5146 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid1972 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2567 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid846 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2587 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid1595 @@ -25582,13 +25575,15 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid6833 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid3109 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid4284 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid6597 @@ -25596,7 +25591,6 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid4274 @@ -25608,6 +25602,7 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid870 @@ -25618,6 +25613,7 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid4312 @@ -25630,6 +25626,7 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid3039 @@ -25643,6 +25640,7 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid7054 @@ -25657,7 +25655,6 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid1061 @@ -25665,24 +25662,27 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + - - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid2609 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid4274 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2987 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid1622 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid3028 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid7092 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid4284 @@ -25695,7 +25695,6 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid3039 @@ -25703,36 +25702,34 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid1988 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid6443 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2759 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid1978 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid4312 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6817 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid509 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid4320 @@ -25744,12 +25741,11 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6793 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid4238 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6491 @@ -25759,59 +25755,59 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid3005 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2609 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid2789 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6515 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid5146 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid6825 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid6691 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6691 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid4303 - + - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid6833 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2867 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid3669 @@ -25825,6 +25821,7 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid672 @@ -25836,6 +25833,7 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid3045 @@ -25844,11 +25842,9 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid1895 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid2835 @@ -25856,27 +25852,28 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid7030 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid2867 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2789 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid6817 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid3012 - + @@ -25885,9 +25882,11 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid6491 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid1988 @@ -25896,16 +25895,20 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid894 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid6699 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid1014 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid3036 @@ -25921,35 +25924,36 @@ _:Bf007c20cX2Ddd1eX2D4491X2D8ef8X2D2dadc51040e2genid60891 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid3028 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid3109 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid1895 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid1963 + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid1963 - + + _:Bb5e57633X2Db0efX2D43d9X2Da7dfX2Db17dfeadbc83genid2744 - _:B930e3bd7X2D68cbX2D4c1fX2Da3a2X2D6b6fcb283c0agenid2826 diff --git a/src/ontology/reports/synonyms.tsv b/src/ontology/reports/synonyms.tsv index 4bca3b9..94445bf 100644 --- a/src/ontology/reports/synonyms.tsv +++ b/src/ontology/reports/synonyms.tsv @@ -97,8 +97,8 @@ "regulation of gonad development" "negative regulation of smooth muscle cell differentiation" "leukocyte activation involved in immune response" - "phosphorus oxoacid derivative" "scleral cell" + "phosphorus oxoacid derivative" "cilium-dependent cell motility" "acetylcholine transmembrane transporter activity" "exopolysaccharide" @@ -117,8 +117,8 @@ "elemental molecular entity" "regulation of cell projection assembly" "nuclear complex of neuraxis" - "keratocyte" "proximal-distal subdivision of colon" + "keratocyte" "cranial ganglion morphogenesis" "regulation of gastro-intestinal system smooth muscle contraction" "pericardial fluid" @@ -217,8 +217,8 @@ "organism substance" "nuclear envelope organization" "mandibular process mesenchyme from head mesenchyme" - "acetate ester transmembrane transporter activity" "submucosa of common hepatic duct" + "acetate ester transmembrane transporter activity" "pronephric nephron tubule epithelial cell" "negative regulation of gastric mucosal blood circulation" "chalcogen oxoacid" @@ -287,20 +287,20 @@ "biogenic amine secreting cell" "Palaeognathae" "ventral horn of spinal cord" - "negative regulation of endothelial cell proliferation" "skin of body" + "negative regulation of endothelial cell proliferation" "subcylindrical" "respiratory primordium" - "urinary bladder" "mesenchymal stem cell of adipose tissue" + "urinary bladder" "blastula stage" "olfactory region" "post-Golgi vesicle-mediated transport" "insect embryonic/larval head sense organ" "cellular homeostasis" "trophectodermal cell" - "presynapse assembly" "myeloid lineage restricted progenitor cell" + "presynapse assembly" "regionalization" "monosaccharide biosynthetic process" "positive regulation of ossification" @@ -327,10 +327,10 @@ "regulation of vacuolar transport" "tendon development" "negative regulation of cardiac muscle contraction" - "kidney interstitium" "regulation of pigment cell differentiation" - "cavitated compound organ" + "kidney interstitium" "iris epithelium" + "cavitated compound organ" "regulation of intracellular lipid transport" "metanephric nephron tubule formation" "regulation of hematopoietic progenitor cell differentiation" @@ -341,9 +341,9 @@ "vasculature of integument" "right ovary" "neural cell adhesion molecule 1 (mouse)" - "gastrointestinal system smooth muscle" "negative regulation of microtubule nucleation" "multicellular organismal-level homeostasis" + "gastrointestinal system smooth muscle" "positive regulation of skeletal muscle cell differentiation" "vulval vein" "diatomic oxygen" @@ -405,15 +405,15 @@ "right horn of sinus venosus" "internal female genitalia" "negative regulation of macromolecule biosynthetic process" - "regulation of mesonephros development" "acinar" + "regulation of mesonephros development" "liver trabecula formation" "pancreatic A cell differentiation" "monosaccharide transmembrane transporter activity" "positive regulation of chorionic trophoblast cell proliferation" "glycogen catabolic process" - "respiratory system capillary" "bulbus cordis" + "respiratory system capillary" "hepatobiliary system" "cranial muscle" "trophoblast cell" @@ -440,8 +440,8 @@ "bicarbonate transmembrane transporter activity" "negative regulation of nervous system development" "positive regulation of smooth muscle cell differentiation" - "sigmoid colon" "cytokine production involved in immune response" + "sigmoid colon" "regional part of nervous system" "regulation of excretion" "negative regulation of developmental pigmentation" @@ -486,8 +486,8 @@ "respiratory system muscle" "regulation of transferase activity" "endocardium of right ventricle" - "anal sac gland secretion" "skeletal myofibril assembly" + "anal sac gland secretion" "organelle lumen" "negative regulation of T cell proliferation" "cell proliferation involved in pronephros development" @@ -637,13 +637,13 @@ "pelvic complex" "tube morphogenesis" "nerve development" - "molecular entity" "nucleate erythrocyte maturation" - "hepatic mesenchymal stem cell" "neuronal dense core vesicle organization" + "molecular entity" + "hepatic mesenchymal stem cell" "serosa of infundibulum of uterine tube" - "regulation of small molecule metabolic process" "transferrin receptor protein 1 (human)" + "regulation of small molecule metabolic process" "renal capsule development" "efferent neuron" "skeleton of pelvic complex" @@ -659,8 +659,8 @@ "actin cytoskeleton organization" "brainstem development" "fibroblast proliferation involved in heart morphogenesis" - "pancreas left lobe" "positive regulation of skeletal muscle fiber development" + "pancreas left lobe" "positive regulation of ion transmembrane transporter activity" "metanephric tubule morphogenesis" "glial cell differentiation" @@ -693,8 +693,8 @@ "artery of lip" "developmental process" "sensory perception of pain" - "notochordal fluid" "positive regulation of cell-cell adhesion" + "notochordal fluid" "regulation of synaptic transmission, cholinergic" "epidermal cell" "negative regulation of mitotic nuclear division" @@ -721,8 +721,8 @@ "blood vessel endothelium" "regulation of fibroblast proliferation" "cilium disassembly" - "female gamete" "musculature of body" + "female gamete" "positive regulation of growth" "primitive nephron" "postsynaptic cytoskeleton" @@ -742,8 +742,8 @@ "bile acid and bile salt transport" "Neopterygii" "seminal fluid" - "regulation of protein localization to plasma membrane" "pigment epithelium of eye" + "regulation of protein localization to plasma membrane" "endodermal cell" "oral lamina propria" "RNA localization" @@ -795,9 +795,9 @@ "negative regulation of hematopoietic progenitor cell differentiation" "active transmembrane transporter activity" "2-D shape" - "ureter smooth muscle" - "hydrogensulfate" "skeletal muscle tissue of pharynx" + "hydrogensulfate" + "ureter smooth muscle" "glandular cuboidal epithelium" "muscle layer of anal canal" "kidney pelvis smooth muscle" @@ -808,8 +808,8 @@ "catechol-containing compound biosynthetic process" "primitive mesonephric nephron" "male reproductive gland" - "membrane bone" "regulation of glycogen catabolic process" + "membrane bone" "organic hydroxy compound transport" "yellow bone marrow" "T-cell surface glycoprotein CD3 epsilon chain (human)" @@ -854,10 +854,10 @@ "hexose metabolic process" "arteriole" "ciliary muscle cell" - "regulation of epithelial cell migration" "parietal peritoneum" - "conjugated protein" "organic anion transport" + "regulation of epithelial cell migration" + "conjugated protein" "nucleus of superior olivary complex" "cytoplasmic region" "6th arch mesenchyme from head mesenchyme" @@ -888,8 +888,8 @@ "mammalian vulva" "endocardium of left ventricle" "endocardial cell differentiation" - "glandular columnar epithelium" "primary circulatory organ" + "glandular columnar epithelium" "progenitor cell" "regulation of cell proliferation involved in embryonic placenta development" "cell-cell signaling involved in pronephros development" @@ -930,8 +930,8 @@ "skin of pelvis" "organogenesis stage" "epithelial sac" - "organ part" "elemental sodium" + "organ part" "negative regulation of intracellular signal transduction" "norepinephrine biosynthetic process" "internal genitalia morphogenesis" @@ -1022,8 +1022,8 @@ "organic hydroxy compound" "negative regulation of response to external stimulus" "lung primordium" - "interventricular septum membranous part" "regulation of morphogenesis of a branching structure" + "interventricular septum membranous part" "execution phase of apoptosis" "central nervous system vasculogenesis" "immature" @@ -1041,8 +1041,8 @@ "phosphorus molecular entity" "lower urinary tract cell" "phosphorylation" - "1st arch mandibular component" "head paraxial mesoderm" + "1st arch mandibular component" "polysaccharide catabolic process" "sulfate transmembrane transporter activity" "negative regulation of skeletal muscle fiber development" @@ -1077,8 +1077,8 @@ "muscle organ morphogenesis" "organelle" "nephric duct" - "positive regulation of cardiac muscle fiber development" "negative regulation of leukocyte cell-cell adhesion" + "positive regulation of cardiac muscle fiber development" "dendritic cell proliferation" "AV node cell to bundle of His cell signaling" "post-anal tail morphogenesis" @@ -1116,15 +1116,15 @@ "tetrapyrrole" "microtubule" "metanephros cortex" - "excreta" "anterior/posterior pattern specification involved in pronephros development" "haploid cell" + "excreta" "negative regulation of cellular biosynthetic process" "cadherin-5" "macromolecule localization" "pancreas right lobe" - "vasculature of musculoskeletal system" "tendon sheath" + "vasculature of musculoskeletal system" "regulation of cell division" "organic molecular entity" "musculature of pelvic complex" @@ -1139,11 +1139,11 @@ "kidney collecting duct epithelial cell" "smooth muscle layer in fatty layer of subcutaneous tissue" "rectal lumen" + "splanchnic layer of lateral plate mesoderm" "Batrachia" "regulation of mononuclear cell proliferation" "negative regulation of erythrocyte apoptotic process" "sodium ion transport" - "splanchnic layer of lateral plate mesoderm" "negative regulation of protein localization to plasma membrane" "regulation of collagen metabolic process" "metanephric mesenchyme development" @@ -1152,8 +1152,8 @@ "regulation of exosomal secretion" "Ascomycota" "broad ligament of uterus" - "endometrial stroma" "membrane organization" + "endometrial stroma" "negative regulation of catabolic process" "neural tube mantle layer" "tryptaminium" @@ -1448,10 +1448,10 @@ "nuclear migration along microfilament" "pulmonary artery endothelium" "embryonic development via the syncytial blastoderm" - "presumptive ectoderm" "tunica intima of artery" "negative regulation of cardiac ventricle formation" "multicellular organism development" + "presumptive ectoderm" "regulation of nervous system process" "trunk paraxial mesoderm" "interventricular septum muscular part" @@ -1564,8 +1564,8 @@ "negative regulation of synapse assembly" "positive regulation of trophectodermal cell proliferation" "bilirubin transport" - "retinal cell programmed cell death" "regulation of respiratory system process" + "retinal cell programmed cell death" "positive regulation of T cell differentiation" "nucleobase-containing small molecule metabolic process" "nonmetal atom" @@ -1624,8 +1624,8 @@ "negative regulation of kinase activity" "positive regulation of acetate catabolic process" "actin filament" - "midbrain tegmentum" "bleb assembly" + "midbrain tegmentum" "regulation of phosphate transmembrane transport" "thoracic segment blood vessel" "ejaculatory duct" @@ -1712,8 +1712,8 @@ "negative regulation of production of molecular mediator of immune response" "glucan catabolic process" "space surrounding organism" - "data item"@en "fibrous connective tissue" + "data item"@en "gland of anal canal" "regulation of myeloid leukocyte mediated immunity" "mesonephric duct lumen" @@ -1778,8 +1778,8 @@ "hepatic sinusoid" "response to organic cyclic compound" "myocardium" - "pneumatic cavity of bone" "Drosophila melanogaster" + "pneumatic cavity of bone" "spinal cord segment" "ectoderm development" "angiogenesis" @@ -1801,15 +1801,15 @@ "vascular plexus" "regulation of fat cell differentiation" "trabecula carnea" - "Saccharomyces cerevisiae" "positive regulation of neuron projection development" + "Saccharomyces cerevisiae" "mesentery of rectum" "sulfate transmembrane transport" "vascular associated smooth muscle cell migration" - "spleen smooth muscle" - "chemical entity" "retinal cone cell differentiation" + "chemical entity" "negative regulation of cellular amino acid metabolic process" + "spleen smooth muscle" "brachiocephalic artery" "negative regulation of immune system process" "solvent" @@ -1825,9 +1825,9 @@ "phenols" "Dictyostelia" "positive regulation of multicellular organismal process" + "pseudostratified columnar epithelium" "nephron tubule development" "blood lymphocyte" - "pseudostratified columnar epithelium" "surface of epithelium" "chondrocyte" "positive regulation of catalytic activity" @@ -1875,14 +1875,14 @@ "photoreceptor cell differentiation" "subdivision of digestive tract" "superelliptic" + "norepinephrine metabolic process" "descending aorta development" "pancreatic A cell development" - "norepinephrine metabolic process" "behavior process" - "mesonephric nephron epithelium development" "myocardial endocrine cell" "heterocycle metabolic process" "stem cell differentiation" + "mesonephric nephron epithelium development" "response to abiotic stimulus" "positive regulation of cardiac chamber formation" "indole alkaloid biosynthetic process" @@ -1892,8 +1892,8 @@ "negative regulation of nervous system process" "negative regulation of cell proliferation involved in kidney development" "thoracic vein" - "male germ cell" "carbohydrate transport" + "male germ cell" "cytoplasm" "cervical spinal cord gray matter" "negative regulation of myotube differentiation" @@ -2026,8 +2026,8 @@ "aldohexose" "ammonium ion metabolic process" "regulation of microtubule nucleation" - "regulation of blood vessel branching" "submucosal esophageal gland" + "regulation of blood vessel branching" "regulation of metanephros development" "spermatogenesis" "positive regulation of synapse assembly" @@ -2069,8 +2069,8 @@ "sulfur compound biosynthetic process" "hepatoblast"@en "tunica media" - "negative regulation of heart contraction" "ciliated epithelium" + "negative regulation of heart contraction" "cardiac ventricle development" "dermis blood vessel endothelial cell" "migrating mesenchyme population" @@ -2199,8 +2199,8 @@ "negative regulation of protein-containing complex assembly" "positive regulation of protein localization to cell-cell junction" "algal metabolite" - "regulation of ureter smooth muscle cell differentiation" "positive regulation of T cell activation" + "regulation of ureter smooth muscle cell differentiation" "neural crest cell development" "regulation of phosphorylation" "splenic artery" @@ -2208,8 +2208,8 @@ "systemic vein" "positive regulation of translational initiation in response to stress" "regulation of polysaccharide metabolic process" - "uterine gland development" "orifice of skull" + "uterine gland development" "syncytium formation by plasma membrane fusion" "monoatomic cation" "peritoneal cavity mesothelium" @@ -2225,8 +2225,8 @@ "regulation of deoxyribonuclease activity" "negative regulation of multicellular organismal process" "protein-DNA complex transport" - "intestinal epithelial cell development" "hindgut contraction" + "intestinal epithelial cell development" "right ventricular trabecular myocardium" "larval" "negative regulation of catalytic activity" @@ -2236,16 +2236,16 @@ "cell adhesion involved in heart morphogenesis" "mesenchymal stem cell migration" "negative regulation of motor neuron apoptotic process" + "dorsal pancreas" "blastula" "blastocyst formation" - "dorsal pancreas" "mesonephric duct development" "atrioventricular node cell differentiation" "negative regulation of carbohydrate metabolic process" - "nucleate erythrocyte development" "nervous system development" - "oral gland" + "nucleate erythrocyte development" "elemental molecule" + "oral gland" "regulation of chromosome condensation" "dermis connective tissue" "endothelial tube morphogenesis" @@ -2257,8 +2257,8 @@ "epithelial cord" "positive regulation of nervous system process" "matrix-based tissue" - "negative regulation of fat cell differentiation" "neural tube basal plate" + "negative regulation of fat cell differentiation" "conus arteriosus formation" "response to ammonium ion" "Mullerian duct" @@ -2291,9 +2291,9 @@ "vascular element of right lung" "bile acid secretion" "upper back muscle" - "myelencephalon sulcus limitans" "urethral gland" "indole alkaloid" + "myelencephalon sulcus limitans" "cortical collecting duct development" "positive regulation of vascular endothelial cell proliferation" "adventitia" @@ -2316,8 +2316,8 @@ "mesothelial cell of visceral peritoneum" "submucosa of pharynx" "negative regulation of acetylcholine secretion, neurotransmission" - "renal artery" "bone of reproductive organ" + "renal artery" "phosphate ion transport" "positive regulation of transport" "binucleate cell" @@ -2383,9 +2383,9 @@ "regulation of apoptotic process involved in development" "polychromatophilic erythroblast" "positive regulation of exocytosis" - "dense regular connective tissue" "polymeric" "pharmacological role" + "dense regular connective tissue" "actin filament bundle" "notochordal canal" "regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction" @@ -2395,8 +2395,8 @@ "regulation of respiratory gaseous exchange by nervous system process" "fungal cell" "cranial skeletal system development" - "noradrenergic neuron differentiation involved in brainstem development" "tetrapod frontal bone" + "noradrenergic neuron differentiation involved in brainstem development" "mixed ectoderm/mesoderm/endoderm-derived structure" "Golgi disassembly" "positive regulation of leukocyte proliferation" @@ -2412,8 +2412,8 @@ "negative regulation of plasma membrane bounded cell projection assembly" "proteinogenic amino-acid residue" "establishment or maintenance of microtubule cytoskeleton polarity" - "respiratory system submucosa" "cardiac atrium fibroblast" + "respiratory system submucosa" "central nervous system development" "skin of trunk" "embryonic heart tube formation" @@ -2456,8 +2456,8 @@ "negative regulation of epithelial cell differentiation" "negative regulation of mucus secretion" "intestine smooth muscle" - "developing mesenchymal condensation" "respiratory system venous blood vessel" + "developing mesenchymal condensation" "parietal peritoneum development" "bladder microvascular endothelial cell" "heart rudiment formation" @@ -2497,8 +2497,8 @@ "ciliary transition zone" "head development" "positive regulation of metanephros development" - "maxillary nerve" "liver stroma" + "maxillary nerve" "spermatid development" "neuroendocrine cell" "ganglion of central nervous system" @@ -2514,8 +2514,8 @@ "somatic stem cell population maintenance" "organic cyclic compound metabolic process" "epidermal cell differentiation" - "iliac vein" "interleukin-7 receptor subunit alpha (human)" + "iliac vein" "multicellular organism growth" "hematopoietic or lymphoid organ development" "5beta-cholanic acids" @@ -2528,11 +2528,11 @@ "metanephric nephron tubule epithelial cell differentiation" "subdivision of organism along main body axis" "spermatogonium" - "regulation of development, heterochronic" "sphenoid endochondral element" + "muscular coat" + "regulation of development, heterochronic" "visceral serous pericardium" "reproductive behavior" - "muscular coat" "food additive" "negative regulation of hindgut contraction" "Nematoda" @@ -2596,8 +2596,8 @@ "mandibular neural crest" "wall of eyeball" "head or neck skin" - "detection of stimulus involved in sensory perception" "cornea development in camera-type eye" + "detection of stimulus involved in sensory perception" "allantois" "immature eye" "head mesenchyme from mesoderm" @@ -2636,18 +2636,18 @@ "protein catabolic process at postsynapse" "anterograde trans-synaptic signaling" "trunk connective tissue" - "negative regulation of protein localization to nucleolus" - "polysaccharide" "jaw epithelium" + "polysaccharide" + "negative regulation of protein localization to nucleolus" "protein transporter activity" "regulation of photoreceptor cell differentiation" "organ component layer" "epithelial sheet" + "pancreas primordium" "regulation of postsynapse organization" "pancreatic D cell development" "detection of electrical stimulus involved in sensory perception of pain" "endo-epithelial cell" - "pancreas primordium" "blood vessel development" "vein endothelial cell of respiratory system" "pneumatized bone" @@ -2737,9 +2737,9 @@ "ascending aorta" "positive regulation of cell motility" "pleuroperitoneal membrane" + "amino acid transmembrane transporter activity" "pnictogen" "trigeminal nerve development" - "amino acid transmembrane transporter activity" "pronephric nephron tubule" "regulation of mesenchymal cell proliferation" "primitive streak formation" @@ -2781,10 +2781,10 @@ "catalytic activity, acting on a protein" "mesothelium of diaphragm" "basement membrane of epithelium" + "body external integument structure" "male reproductive system" "male reproductive system"@en "cortical collecting duct" - "body external integument structure" "1st arch maxillary component" "negative regulation of transport" "splanchnocranium" @@ -2808,8 +2808,8 @@ "negative regulation of protein-containing complex disassembly" "renal tubular secretion" "positive regulation of glial cell migration" - "exocrine pancreas epithelium" "left lung morphogenesis" + "exocrine pancreas epithelium" "positive regulation of epithelial cell differentiation" "vein of upper lip" "mucosa of left ureter" @@ -2858,18 +2858,18 @@ "glial cell" "renal capsule formation" "negative regulation of nematode larval development" - "vasculature of liver" "regulation of mitotic nuclear envelope disassembly" "head morphogenesis" "regulation of microtubule polymerization or depolymerization" + "vasculature of liver" "positive regulation of multicellular organism growth" "negative regulation of cytokine production" "mesenchymal cell differentiation involved in lung development" "sensory perception of sound" - "layer of sclera" "endocardial endothelium development" - "post-embryonic organism" + "layer of sclera" "muscle layer of oviduct" + "post-embryonic organism" "negative regulation of fat cell proliferation" "yolk sac" "primary subdivision of skull" @@ -3012,8 +3012,8 @@ "spinal cord mantle layer" "myoblast migration" "negative regulation of leukocyte migration" - "body part movement" "circulatory organ" + "body part movement" "future cardiac atrium" "positive regulation of protein localization to nucleolus" "canonical ribonucleotide residue" @@ -3125,8 +3125,8 @@ "anterior vena cava" "synaptic signaling" "regulation of extracellular matrix organization" - "post-juvenile adult stage" "small intestine" + "post-juvenile adult stage" "metanephric ureteric bud" "cardiac pacemaker cell development" "response to endogenous stimulus" @@ -3236,8 +3236,8 @@ "stomach glandular region" "sulfated glycosaminoglycan" "somatic sensory system development" - "chromosome segregation" "caudal vertebra endochondral element" + "chromosome segregation" "stromal cell of pancreas" "neural tube formation" "androgen secreting cell" @@ -3359,9 +3359,9 @@ "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" "respiratory primordium epithelium" "negative regulation of neurotransmitter transport" + "heart development" "amide catabolic process" "endothelial cell of pericentral hepatic sinusoid"@en - "heart development" "chromosome" "detection of light stimulus involved in visual perception" "morphogenesis of an epithelial sheet" @@ -3378,8 +3378,8 @@ "root" "negative regulation of protein catabolic process in the vacuole" "cell cortex" - "proliferating neuroepithelium" "phosphorus oxoacids and derivatives" + "proliferating neuroepithelium" "negative regulation of striated muscle contraction" "ocular refractive media" "positive regulation of cardiac ventricle development" @@ -3463,8 +3463,8 @@ "extraembryonic structure" "intracellular protein transmembrane transport" "left hepatic artery" - "chemical substance" "liver" + "chemical substance" "regulation of protein-containing complex assembly" "back nerve" "negative regulation of type B pancreatic cell apoptotic process" @@ -3474,8 +3474,8 @@ "atomic nucleus" "positive regulation of catecholamine metabolic process" "thoracic cavity" - "pelvic girdle bone/zone" "positive regulation of animal organ morphogenesis" + "pelvic girdle bone/zone" "negative regulation of cell proliferation involved in heart morphogenesis" "positive regulation of vascular associated smooth muscle cell migration" "regulation of adaptive immune response" @@ -3531,8 +3531,8 @@ "lung connective tissue" "ureter ureteric bud" "hematopoietic oligopotent progenitor cell, lineage-negative" - "atrial cardiac muscle tissue morphogenesis" "mesonephros morphogenesis" + "atrial cardiac muscle tissue morphogenesis" "respiratory epithelial cell" "negative regulation of DNA catabolic process" "transmembrane transporter activity" @@ -3551,8 +3551,8 @@ "central vein of liver" "Golgi localization" "myocyte of sinoatrial node" - "detection of electrical stimulus" "renal cortex vein" + "detection of electrical stimulus" "prechondroblast" "indole-containing compound catabolic process" "mononuclear cell" @@ -3594,8 +3594,8 @@ "system" "camera-type eye morphogenesis" "vertebra cartilage element" - "vacuolar transmembrane transport" "mesonephric collecting duct" + "vacuolar transmembrane transport" "positive regulation of insulin secretion" "seminal vesicle epithelium development" "regulation of cardiac muscle cell differentiation" @@ -3712,8 +3712,8 @@ "frontonasal process epithelium" "anatomical junction" "positive regulation of leukocyte activation" - "esophagus secretion" "pharyngeal arch cartilage" + "esophagus secretion" "positive regulation of gonad development" "gravid organism" "ingression involved in gastrulation with mouth forming second" @@ -3726,8 +3726,8 @@ "positive regulation of microtubule polymerization or depolymerization" "epithelial layer of duct" "respiratory system mucus" - "clitoral smooth muscle" "Protostomia" + "clitoral smooth muscle" "negative regulation of AV node cell action potential" "insect larval head" "positive regulation of lymphocyte apoptotic process" @@ -3736,8 +3736,8 @@ "negative regulation of epidermis development" "lens placode formation" "regulation of translational elongation" - "neurogenic placode" "myeloid leukocyte activation" + "neurogenic placode" "organic amino compound" "regulation of mesoderm development" "dicarboxylic acids and O-substituted derivatives" @@ -3841,8 +3841,8 @@ "positive regulation of protein catabolic process in the vacuole" "electrically responsive cell" "organic acid metabolic process" - "diaphragm development" "enveloping layer of ectoderm" + "diaphragm development" "larva" "lumen of blood vessel" "female urethral meatus" @@ -3872,8 +3872,8 @@ "bone collagen fibril" "protein localization to cilium" "skin of lip" - "heart vasculature" "trophectodermal cell differentiation" + "heart vasculature" "efferent duct epithelium" "nucleon" "serous acinus" @@ -3887,12 +3887,12 @@ "Eurypterygia" "peritoneal sac" "bladder organ" - "positive regulation of cytokine production involved in immune response" "negative regulation of neuronal action potential" + "positive regulation of cytokine production involved in immune response" "distensible" "urethral opening" - "tunica adventitia of blood vessel" "epithelium of rectum" + "tunica adventitia of blood vessel" "regulation of stem cell differentiation" "abdominal ganglion" "optic vesicle formation" @@ -3906,9 +3906,9 @@ "regulation of tetrapyrrole catabolic process" "regulation of type B pancreatic cell proliferation" "acetate transmembrane transporter activity" + "Escherichia coli metabolite" "positive regulation of sodium ion transport" "glycosaminoglycan" - "Escherichia coli metabolite" "visceral pleura" "intestinal enteroendocrine cell" "regulation of basement membrane organization" @@ -3956,8 +3956,8 @@ "nuclear chromosome segregation" "microcirculatory vessel" "cartilaginous condensation" - "pectoral girdle skeleton" "nephric ridge" + "pectoral girdle skeleton" "positive regulation of cell proliferation involved in heart morphogenesis" "wall of uterine tube" "chromosome condensation" @@ -3973,8 +3973,8 @@ "gland" "cell proliferation in midbrain" "azanide" - "endocardial cushion development" "fibrinogen complex" + "endocardial cushion development" "enteric smooth muscle cell" "positive regulation of macromolecule metabolic process" "chromosome organization involved in meiotic cell cycle" @@ -4014,16 +4014,16 @@ "N-acylglucosamine" "neural crest cell differentiation" "chalcogen" - "noradrenergic cell groups" "positive regulation of extracellular matrix organization" + "noradrenergic cell groups" "Eremoneura" - "metanephric smooth muscle tissue" "glial cell projection" + "metanephric smooth muscle tissue" "organic univalent group" "atrioventricular node cell development" "left hepatic vein" - "carbohydrate sulfate" "positive regulation of intracellular protein transport" + "carbohydrate sulfate" "regulation of cardiac muscle cell myoblast differentiation" "embryonic structure" "inorganic anion transport" @@ -4033,8 +4033,8 @@ "enucleate erythrocyte" "negative regulation of glycogen biosynthetic process" "cardiac muscle hypertrophy" - "intraciliary transport" "quality of a solid" + "intraciliary transport" "entire surface of organism" "vasculature of iris" "nephrogenic zone cell" @@ -4120,8 +4120,8 @@ "negative regulation of apoptotic process involved in outflow tract morphogenesis" "carboxamide" "regulation of dendritic cell apoptotic process" - "fungal metabolite" "vacuole" + "fungal metabolite" "pectoral girdle region" "negative regulation of vascular associated smooth muscle cell proliferation" "ciliated epithelial cell of esophagus" @@ -4131,17 +4131,17 @@ "neuron projection membrane" "blood" "cranial neural crest" - "adventitia of epididymis" "regulation of endothelial cell activation" + "adventitia of epididymis" "glycoprotein" "negative regulation of mesoderm development" "acidophilic cytoplasm" "kidney mesenchyme" "esophageal sphincter" "negative regulation of amide metabolic process" + "duodenum lamina propria" "positive regulation of transferase activity" "non-striated muscle cell" - "duodenum lamina propria" "muscle cell cellular homeostasis" "venule of colon" "gravid uterus" @@ -4174,8 +4174,8 @@ "Myomorpha" "multipotent" "regulation of blood vessel endothelial cell migration" - "nonsynovial joint" "cellular anatomical entity morphogenesis" + "nonsynovial joint" "negative regulation of apoptotic process involved in metanephric nephron tubule development" "regulation of locomotion involved in locomotory behavior" "protein localization to chromosome" @@ -4196,8 +4196,8 @@ "detection of stimulus involved in sensory perception of pain" "glial cell development" "medial-nasal process ectoderm" - "reticular formation" "negative regulation of hematopoietic stem cell proliferation" + "reticular formation" "blood vessel maturation" "sperm plasma membrane" "hydrides" @@ -4216,9 +4216,9 @@ "mononuclear cell of umbilical cord" "pancreas secretion" "negative regulation of cardiac myofibril assembly" - "male genital duct" "regulation of nucleobase-containing compound transport" "cranial nerve nucleus" + "male genital duct" "serotonin catabolic process" "negative regulation of amino acid biosynthetic process" "dense core granule maturation" @@ -4297,8 +4297,8 @@ "future upper lip" "airway submucosal gland" "replacement element" - "CNS interneuron" "embryonic cloaca" + "CNS interneuron" "positive regulation of stem cell population maintenance" "response to organonitrogen compound" "locomotion" @@ -4335,8 +4335,8 @@ "establishment of vesicle localization" "muscle of vertebral column" "pleural cavity" - "response to glucose" "hermaphroditic organism" + "response to glucose" "bilaminar disc" "negative regulation of spermatid nuclear differentiation" "Pancrustacea" @@ -4373,8 +4373,8 @@ "atrial cardiac muscle tissue development" "fibroblast growth factor 8 (mouse)" "regulation of amine metabolic process" - "endocardium development" "mesentery of foregut-midgut junction" + "endocardium development" "Chromadorea" "arch of aorta" "male pronucleus" @@ -4386,11 +4386,11 @@ "dense core granule localization" "Struthio camelus" "tunica adventitia of artery" - "molecule" "nucleoside residue" "protein localization to nuclear envelope" - "mitotic nuclear membrane organization" + "molecule" "pelvic girdle skeleton" + "mitotic nuclear membrane organization" "regulation of cardiocyte differentiation" "apoptotic nuclear changes" "excretion" @@ -4447,8 +4447,8 @@ "positive regulation of pigment cell differentiation" "aorta endothelium" "response to external stimulus" - "pronephros development" "regulation of lymphocyte proliferation" + "pronephros development" "positive regulation of nephron tubule epithelial cell differentiation" "steroid" "bile acid biosynthetic process" @@ -4466,17 +4466,17 @@ "organic sodium salt" "quality of a gas" "supramolecular fiber" - "positive regulation of syncytium formation by plasma membrane fusion" "somatic muscle, invertebrate" "somatic muscle"@en + "positive regulation of syncytium formation by plasma membrane fusion" "kidney smooth muscle tissue development" "exosomal secretion" "organic hydroxy compound transmembrane transporter activity" "regulation of acetylcholine metabolic process" "negative regulation of lipid biosynthetic process" "musculature of pelvic girdle" - "crustacean metabolite" "respiratory system artery" + "crustacean metabolite" "intermediate mesoderm development" "megakaryocyte development" "positive regulation of meiotic cell cycle" @@ -4501,9 +4501,9 @@ "EC 3.5.1.4 (amidase) inhibitor" "os clitoris" "mesenchymal to epithelial transition" - "chorioretinal region" "anatomical structure quality" "mucosa of cystic duct" + "chorioretinal region" "cell differentiation involved in metanephros development" "lipid export from cell" "oogenesis" @@ -4513,10 +4513,10 @@ "positive regulation of cardiac muscle tissue development" "polyploid" "nucleophilic reagent" - "epithelial cell of uterus" "metanephric nephron epithelium development" - "neurotoxin" + "epithelial cell of uterus" "positive regulation of endothelial cell differentiation" + "neurotoxin" "skin muscle" "retina morphogenesis in camera-type eye" "presomitic mesoderm" @@ -4579,8 +4579,8 @@ "thoracic vertebral foramen" "negative regulation of cardiac muscle cell proliferation" "chorionic mesenchyme" - "negative regulation of transferase activity" "entire pharyngeal arch endoderm" + "negative regulation of transferase activity" "positive regulation of cardiac muscle cell myoblast differentiation" "acid secretion" "smooth muscle cell apoptotic process" @@ -4661,11 +4661,11 @@ "negative regulation of cardiac muscle hypertrophy" "regulation of kidney development" "presumptive pronephric mesoderm" - "caudal vertebra pre-cartilage condensation" "paired limb/fin bud mesenchyme" + "caudal vertebra pre-cartilage condensation" "micronutrient" - "cellular response to stimulus" "mesenteric vein" + "cellular response to stimulus" "lobe of liver" "simple cuboidal epithelium" "lobule" @@ -4712,10 +4712,10 @@ "mouth movement" "mesenchyme of ovary" "Acanthomorphata" - "developing anatomical structure" "trachea morphogenesis" "placental labyrinth vasculature" "midbrain-hindbrain boundary maturation" + "developing anatomical structure" "vascular associated smooth muscle cell differentiation" "spermatic cord" "common myeloid progenitor" @@ -4740,8 +4740,8 @@ "pronephric nephron tubule development" "positive regulation of amino acid biosynthetic process" "macronutrient" - "dilatator pupillae" "negative regulation of amine catabolic process" + "dilatator pupillae" "negative regulation of embryonic camera-type eye development" "regulation of locomotion" "mesonephric tubule development" @@ -4784,9 +4784,9 @@ "regulation of lipid catabolic process" "sex differentiation" "meiosis II cell cycle process" - "adult skeletal muscle myoblast" - "thoracic skeleton" "subserosa of uterine tube" + "thoracic skeleton" + "adult skeletal muscle myoblast" "nutrient" "metabolite" "regulation of establishment of T cell polarity" @@ -4796,9 +4796,9 @@ "cell communication involved in cardiac conduction" "positive regulation of protein localization to presynapse" "endothelium development" - "muscle layer of cloaca" "negative regulation of hepatocyte apoptotic process" "smooth muscle adaptation" + "muscle layer of cloaca" "T cell secretory granule organization" "negative regulation of lymphocyte apoptotic process" "ribosome assembly" @@ -4826,8 +4826,8 @@ "cellular component organization or biogenesis" "chorionic villus" "negative regulation of cardiocyte differentiation" - "lens epithelial cell" "peptide secretion" + "lens epithelial cell" "digestive system duct" "body fluid secretion" "nuclear protein-containing complex" @@ -4843,11 +4843,11 @@ "positive regulation of tetrapyrrole catabolic process" "meso-epithelium" "endometrium epithelium" - "parenchyma of pancreas" + "left cardiac atrium" "bile acid transmembrane transporter activity" "gliogenesis" + "parenchyma of pancreas" "positive regulation of protein metabolic process" - "left cardiac atrium" "pigment granule organization" "pulmonary capillary" "regulation of establishment of protein localization to chromosome" @@ -4869,12 +4869,12 @@ "mesothelium of serous pericardium" "pharyngeal arch artery morphogenesis" "cellularity" - "rhombencephalon neural crest" "female germ line stem cell" + "rhombencephalon neural crest" "kidney nerve cell" "regulation of gastric acid secretion" - "neural crest derived neuroblast" "submucosal gland acinus" + "neural crest derived neuroblast" "mitotic cell cycle process" "positive regulation of lymphocyte proliferation" "negative regulation of amine metabolic process" @@ -5023,8 +5023,8 @@ "acylcholine" "simple columnar epithelium" "pharyngeal gland" - "negative regulation of T cell homeostatic proliferation" "vacuolar lumen" + "negative regulation of T cell homeostatic proliferation" "ammonium transmembrane transport" "anatomical lobe" "atrioventricular node development" @@ -5035,8 +5035,8 @@ "orbit of skull" "metanephric mesenchyme" "cardiac chamber" - "sensory perception" "primordial germ cell" + "sensory perception" "adventitia of ductus deferens" "arcuate ligament" "polychromatophilic cytoplasm" @@ -5083,8 +5083,8 @@ "microtubule bundle" "regulation of cell proliferation involved in compound eye morphogenesis" "epithelium of pancreatic duct" - "lumen of anal canal" "myoblast division" + "lumen of anal canal" "positive regulation of defense response to bacterium" "cloacal gland development" "response to oxygen-containing compound" @@ -5194,8 +5194,8 @@ "polyanionic macromolecule" "negative regulation of lung ciliated cell differentiation" "regulation of lymphocyte mediated immunity" - "electrically signaling cell" "endoderm of foregut" + "electrically signaling cell" "negative regulation of protein metabolic process" "liver dendritic cell" "skeletal element" @@ -5210,8 +5210,8 @@ "serous pericardium" "regulation of peptide secretion" "Embryophyta" - "musculature" "lumen of hindgut" + "musculature" "digestive system development" "midbrain nucleus" "T-cell surface glycoprotein CD4 (human)" @@ -5253,8 +5253,8 @@ "oxygen atom" "Chondrostei" "ciliated cell" - "insulin metabolic process" "establishment of localization in cell" + "insulin metabolic process" "regulation of placenta blood vessel development" "cell-cell signaling involved in lung development" "anti-inflammatory drug" @@ -5290,8 +5290,8 @@ "regulation of polysaccharide biosynthetic process" "midbrain basal plate" "systemic artery" - "intrahepatic cholangiocyte" "CD34 molecule" + "intrahepatic cholangiocyte" "neuroinflammatory response" "modulation of chemical synaptic transmission" "cell differentiation involved in kidney development" @@ -5305,8 +5305,8 @@ "carbohydrate catabolic process" "regulation of erythrocyte differentiation" "spinal cord neural crest" - "epididymis epithelium" "pancreatic juice" + "epididymis epithelium" "defense response to insect" "lower lip" "respiratory airway" @@ -5334,8 +5334,8 @@ "endocrine process" "medial nasal prominence" "Drosophila " - "liver primordium" "elastic fiber" + "liver primordium" "mononuclear cell migration" "positive regulation of monoatomic ion transmembrane transport" "morula" @@ -5432,8 +5432,8 @@ "cell growth" "somatostatin secreting cell" "medullary ray" - "urinary bladder smooth muscle contraction" "detection of light stimulus" + "urinary bladder smooth muscle contraction" "negative regulation of translational initiation" "regulation of protein secretion" "1st arch maxillary mesenchyme from neural crest" @@ -5455,8 +5455,8 @@ "Canalipalpata" "establishment or maintenance of cytoskeleton polarity involved in gastrulation" "multinucleated phagocyte" - "muscle of pelvis" "positive regulation of cell projection organization" + "muscle of pelvis" "negative regulation of cell proliferation involved in compound eye morphogenesis" "hepatic sinusoid of left of lobe of liver" "material entity in digestive tract" @@ -5493,8 +5493,8 @@ "positive regulation of synapse pruning" "negative regulation of endothelial cell migration" "cuboidal epithelium" - "negative regulation of cell differentiation involved in embryonic placenta development" "musculature of thorax" + "negative regulation of cell differentiation involved in embryonic placenta development" "positive regulation of dermatome development" "esophageal hiatus" "hemopoiesis" @@ -5514,8 +5514,8 @@ "transmission of nerve impulse" "regulation of Golgi organization" "negative regulation of T cell mediated immunity" - "sulfuric acid" "peptide hormone" + "sulfuric acid" "negative regulation of blood circulation" "positive regulation of lipid catabolic process" "skeletal muscle hypertrophy" @@ -5527,8 +5527,8 @@ "organ or tissue specific immune response" "endothelial tube formation" "agrochemical" - "positive regulation of muscle organ development" "axo-dendritic protein transport" + "positive regulation of muscle organ development" "positive regulation of establishment of T cell polarity" "amine transmembrane transporter activity" "regulation of chondrocyte differentiation" @@ -5564,10 +5564,10 @@ "neural retina development" "cytokine production involved in inflammatory response" "neurecto-epithelial cell" + "axial vasculature" "mesentery of stomach" "Sertoli cell" "negative regulation of secondary metabolite biosynthetic process" - "axial vasculature" "catalytic activity" "aromatic compound catabolic process" "type B pancreatic cell" @@ -5604,8 +5604,8 @@ "viscosity" "Eumycetozoan cell" "organelle disassembly" - "oogonial cell" "axial skeleton plus cranial skeleton" + "oogonial cell" "amino acid biosynthetic process" "submucosa of colon" "negative regulation of gastric acid secretion" @@ -5624,8 +5624,8 @@ "artery wall" "gastric gland" "regulation of protein localization to cilium" - "epithelial cell proliferation involved in lung morphogenesis" "mesenchymal cell" + "epithelial cell proliferation involved in lung morphogenesis" "positive regulation of myeloid progenitor cell differentiation" "Tetradontoidea" "embryonic tissue" @@ -5636,8 +5636,8 @@ "retinal cell" "insulin catabolic process" "muscle layer of large intestine" - "regulation of somitogenesis" "mesenchymal-epithelial cell signaling involved in lung development" + "regulation of somitogenesis" "muscle layer of duodenum" "regulation of neurotransmitter secretion" "retina vasculature development in camera-type eye" @@ -5650,14 +5650,14 @@ "post-transcriptional regulation of gene expression" "lower respiratory tract epithelium" "negative regulation of lymphocyte mediated immunity" - "cilium organization" "endoderm of midgut" + "cilium organization" "regulation of vesicle fusion" - "cranial bone" "compound eye photoreceptor cell differentiation" + "cranial bone" "regulation of mitotic sister chromatid segregation" - "negative regulation of neuroblast proliferation" "skeletal musculature" + "negative regulation of neuroblast proliferation" "left testis" "positive regulation of nitrogen compound metabolic process" "skin development" @@ -5677,8 +5677,8 @@ "inorganic ion transmembrane transport" "negative regulation of synaptic transmission" "extracellular organelle" - "T-cell surface glycoprotein CD8 alpha chain (mouse)" "type D cell of stomach" + "T-cell surface glycoprotein CD8 alpha chain (mouse)" "apoptotic process involved in blood vessel morphogenesis" "cytoskeleton" "positive regulation of epidermal cell differentiation" @@ -5773,13 +5773,13 @@ "biladienes" "metanephric tubule development" "cervical region" - "embryonic morphogenesis" "translation at synapse" + "embryonic morphogenesis" "positive regulation of cytoskeleton organization" "negative regulation of cell cycle process" "positive regulation of oocyte maturation" - "spleen trabecular vein" "T-cell surface glycoprotein CD8 alpha chain" + "spleen trabecular vein" "positive regulation of norepinephrine uptake" "endochondral bone growth" "cylindrical" @@ -5794,8 +5794,8 @@ "regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" "sulfur oxoanion" "regulation of neuroinflammatory response" - "thoracic aorta smooth muscle tissue" "visceral fat" + "thoracic aorta smooth muscle tissue" "glans" "mucosa of left uterine tube" "regulation of embryonic pattern specification" @@ -5866,8 +5866,8 @@ "muscular coat of ureter" "regulation of gene expression" "lamina propria of ureter" - "positive regulation of mitotic sister chromatid segregation" "binucleate" + "positive regulation of mitotic sister chromatid segregation" "myofibril" "negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis" "transport" @@ -5885,10 +5885,10 @@ "smooth muscle cell of the umbilical artery" "integumental system" "spinal cord development" - "mitotic nuclear membrane disassembly" "placental villous stroma" - "female reproductive organ" + "mitotic nuclear membrane disassembly" "glucose catabolic process" + "female reproductive organ" "positive regulation of artery morphogenesis" "muscle structure" "nucleic acid" @@ -5906,8 +5906,8 @@ "myotube cell development" "regulation of skeletal muscle cell proliferation" "acid" - "epithelial cell morphogenesis involved in gastrulation" "flagellated sperm cell" + "epithelial cell morphogenesis involved in gastrulation" "epithelial cell apoptotic process" "bone cell" "tryptamines" @@ -5958,9 +5958,9 @@ "Polychaeta" "neural crest formation" "positive regulation of translational initiation" - "nephron tubule basement membrane" - "appendage musculature" "monoatomic ion" + "appendage musculature" + "nephron tubule basement membrane" "positive regulation of T cell mediated immunity" "extraembryonic epithelium" "articular system" @@ -6003,8 +6003,8 @@ "parietal serous pericardium" "embryo development" "fibrous pericardium" - "establishment of T cell polarity" "positive regulation of peptide secretion" + "establishment of T cell polarity" "amino acid catabolic process" "motor neuron migration" "eye photoreceptor cell" @@ -6041,8 +6041,8 @@ "positive regulation of blood circulation" "neuron" "yolk sac cavity" - "response to monosaccharide" "endothelial cell of vascular tree" + "response to monosaccharide" "common atrial chamber" "right atrium endocardium" "fertilizer" @@ -6095,10 +6095,10 @@ "extracellular negative regulation of signal transduction" "phenol-containing compound biosynthetic process" "integrin alpha with A domain" + "hindbrain marginal layer" "morphogenesis of an epithelium" "positive regulation of synaptic transmission" "intracellular membrane-bounded organelle" - "hindbrain marginal layer" "T-cell surface glycoprotein CD8 alpha chain (human)" "protein transport along microtubule" "synovial joint of pectoral girdle" @@ -6114,8 +6114,8 @@ "organic acid catabolic process" "negative regulation of lipid transport" "ventricular cardiac muscle tissue morphogenesis" - "egg cell" "gonad mesenchyme" + "egg cell" "submucosa of duodenum" "response to monoamine" "digestive system" @@ -6140,9 +6140,9 @@ "vasculogenesis involved in coronary vascular morphogenesis" "phagocyte (sensu Vertebrata)" "epicardium morphogenesis" - "organelle transport along microtubule" "stemma" "stemma"@en + "organelle transport along microtubule" "mononuclear phagocyte" "transepithelial transport" "epithelial cell" @@ -6192,8 +6192,8 @@ "hematopoietic progenitor cell differentiation" "nerve of cervical vertebra" "abdominopelvic cavity" - "serotonin" "hepaticobiliary system process" + "serotonin" "hematopoietic system" "optic choroid" "pre-muscle condensation" @@ -6275,9 +6275,9 @@ "Danio" "meiotic sister chromatid segregation" "male reproductive organ" + "positive regulation of chondrocyte development" "small molecule catabolic process" "ribonucleic acid" - "positive regulation of chondrocyte development" "epicardial fat" "positive regulation of signaling" "plasma membrane bounded cell projection morphogenesis" @@ -6296,8 +6296,8 @@ "nephrogenic mesenchyme" "lamina propria of trachea" "mesonephric renal vesicle formation" - "metanephric renal vesicle morphogenesis" "Gnetales" + "metanephric renal vesicle morphogenesis" "acetate ester" "Purkinje myocyte development" "urogenital sinus lumen" @@ -6320,8 +6320,8 @@ "outflow tract pericardium" "pulmonary venule" "euploid" - "columnar/cuboidal epithelial cell" "nucleobase-containing compound biosynthetic process" + "columnar/cuboidal epithelial cell" "future coelemic cavity lumen" "outflow tract pulmonary component" "system process" @@ -6370,8 +6370,8 @@ "carbon group molecular entity" "skin mucous gland" "regulation of skeletal muscle hypertrophy" - "acetate catabolic process" "organochalcogen compound" + "acetate catabolic process" "positive regulation of collagen biosynthetic process" "reproductive gland secretion" "neck cartilage" @@ -6473,8 +6473,8 @@ "skeletal muscle fiber differentiation" "placenta blood vessel development" "regulation of bile acid secretion" - "trans-synaptic signaling via exosome" "protein localization to nucleus" + "trans-synaptic signaling via exosome" "islet of Langerhans" "regulation of vascular associated smooth muscle cell apoptotic process" "extracellular matrix" @@ -6528,14 +6528,14 @@ "oocyte morphogenesis" "liver blood vessel" "vesical artery" - "heart elastic tissue" "apoptotic process involved in metanephric nephron tubule development" + "heart elastic tissue" "carbamoyl group" "mucosa of female urethra" "negative regulation of striated muscle tissue development" + "vesical vein" "nephron epithelium morphogenesis" "cardiac neural crest cell development involved in outflow tract morphogenesis" - "vesical vein" "pyloric sphincter" "visceral abdominal adipose tissue" "negative regulation of cartilage development" @@ -6548,8 +6548,8 @@ "urethra smooth muscle layer" "Sertoli cell differentiation" "myeloid cell development" - "dendritic cell dendrite" "male genitalia development" + "dendritic cell dendrite" "head sensillum" "primary amide" "substantia propria of cornea" @@ -6618,8 +6618,8 @@ "serous gland" "future dermis" "lens of camera-type eye" - "iliac vein endothelium" "hexose" + "iliac vein endothelium" "urethra cell" "palate bone" "response to external biotic stimulus" @@ -6681,9 +6681,9 @@ "coelom" "diploid" "neck nerve" - "closure" "nucleobase-containing compound catabolic process" "inorganic cation transmembrane transporter activity" + "closure" "intraembryonic coelom" "positive regulation of myoblast differentiation" "positive regulation of steroid biosynthetic process" @@ -6695,8 +6695,8 @@ "Dicondylia" "renal vein" "neural plate pattern specification" - "sexually immature organism" "positive regulation of defense response" + "sexually immature organism" "cardiac right ventricle morphogenesis" "regulation of action potential" "septum" @@ -6717,15 +6717,15 @@ "lymphocyte migration" "T-cell acute lymphocytic leukemia protein 1" "negative regulation of skeletal muscle cell proliferation" - "trophoblast cell migration" "caudal region" + "trophoblast cell migration" "pronephric nephron tubule morphogenesis" "regulation of glycogen metabolic process" "female reproductive gland" "positive regulation of collagen catabolic process" "positive regulation of cholangiocyte apoptotic process" - "establishment of protein localization to extracellular region" "positive regulation of vascular associated smooth muscle cell apoptotic process" + "establishment of protein localization to extracellular region" "organic anion" "negative regulation of skeletal muscle hypertrophy" "regulation of acetate catabolic process" @@ -6773,9 +6773,9 @@ "amine biosynthetic process" "regulation of nuclease activity" "neural tube development" - "zygomaticotemporal nerve" "disposition"@en "cadherin-5 (mouse)" + "zygomaticotemporal nerve" "regulation of protein localization to ciliary membrane" "regulation of muscle cell apoptotic process" "signal release from synapse" @@ -6817,8 +6817,8 @@ "axial skeletal system" "artery development" "dorsal trunk" - "positive regulation of cardioblast differentiation" "mesonephric nephron epithelium" + "positive regulation of cardioblast differentiation" "smooth muscle cell neural crest derived" "serosa of rectum" "positive regulation of dendritic cell dendrite assembly" @@ -6826,17 +6826,17 @@ "epithelium of lens" "gallbladder smooth muscle" "Lophotrochozoa" - "negative regulation of hematopoietic stem cell migration" "animal organ maturation" + "negative regulation of hematopoietic stem cell migration" "midgut duodenum mesentery" "professional antigen presenting cell" "capillary of anorectum" "positive regulation of steroid metabolic process" - "abdominal cavity" "cell proliferation involved in embryonic placenta development" "regulation of response to acetate" "specialized cardiac myocyte" "alkaloid metabolic process" + "abdominal cavity" "microtubule bundle formation" "uterine epithelium development" "positive regulation of bile acid secretion" @@ -6858,13 +6858,13 @@ "right lung development" "vasculature of respiratory integument" "polycyclic heteroarene" - "duct epithelial cell" "mitotic sister chromatid segregation" + "duct epithelial cell" "positive regulation of cilium movement" "zygotic determination of anterior/posterior axis, embryo" "flattened" - "morphogenesis of a branching epithelium" "caudal part of nephrogenic cord" + "morphogenesis of a branching epithelium" "regulation of neuroblast proliferation" "cardiac muscle of left atrium" "response to hypoxia" @@ -6930,8 +6930,8 @@ "endothelial cell of arteriole" "regulation of gliogenesis" "wall of small intestine" - "negative regulation of muscle contraction" "liver subserosa" + "negative regulation of muscle contraction" "regulation of Golgi inheritance" "intracellular organelle lumen" "respiratory system skeletal muscle" @@ -6940,8 +6940,8 @@ "migratory cardiac neural crest cell" "gallbladder serosa" "morphogenesis of an epithelial bud" - "myotome development" "neural fold" + "myotome development" "intracellular protein transport" "hindbrain nucleus" "T-cell acute lymphocytic leukemia protein 1 (human)" @@ -6949,8 +6949,8 @@ "compound organ component" "blood vessel morphogenesis" "left renal cortex interstitium" - "pulmonary vein" "skeletal muscle tissue of trunk" + "pulmonary vein" "negative regulation of execution phase of apoptosis" "nephron" "cell proliferation involved in endocardial cushion morphogenesis" @@ -6974,8 +6974,8 @@ "somatic layer of lateral plate mesoderm" "serotonin secretion, neurotransmission" "future diaphragm" - "epithelial-mesenchymal cell signaling involved in lung development" "negative regulation of hepatocyte differentiation" + "epithelial-mesenchymal cell signaling involved in lung development" "transverse cervical artery" "regulation of pronephric nephron tubule development" "respiratory system elastic tissue" @@ -7021,8 +7021,8 @@ "spinal artery" "stromal cell of bone marrow" "embryonic cloacal epithelium" - "smooth muscle cell of sphincter of pupil" "liver right lobe parenchyma" + "smooth muscle cell of sphincter of pupil" "positive regulation of fibroblast apoptotic process" "regulation of secretory granule organization" "negative regulation of cell proliferation involved in mesonephros development" @@ -7042,8 +7042,8 @@ "striated muscle cell differentiation" "eukaryotic metabolite" "transport along microtubule" - "jaw muscle" "kidney mesenchyme development" + "jaw muscle" "negative regulation of somatic muscle development" "acrosome assembly" "interlobar vein" @@ -7076,11 +7076,11 @@ "neuroendocrine cell differentiation" "cortex" "sulfates" + "cardiac muscle tissue of atrium" "epithelial-mesenchymal cell signaling" "nuclear envelope" "apoptotic signaling pathway" "amino-acid residue" - "cardiac muscle tissue of atrium" "Spiralia" "extracellular exosome assembly" "regulation of steroid metabolic process" @@ -7163,8 +7163,8 @@ "regulation of acinar cell proliferation" "negative regulation of glycogen metabolic process" "alpha-amino acid catabolic process" - "compound eye" "inorganic molecular entity transmembrane transporter activity" + "compound eye" "regulation of organ growth" "regulation of cell differentiation involved in embryonic placenta development" "positive regulation of microtubule depolymerization" @@ -7179,8 +7179,8 @@ "regional part of spinal cord" "pectoral girdle bone" "integrin alpha" - "future glans clitoris" "vesicle-mediated transport" + "future glans clitoris" "Saccharomycotina" "undifferentiated genital tubercle" "kidney arterial blood vessel" @@ -7204,12 +7204,12 @@ "N-acyl-hexosamine" "T-cell surface glycoprotein CD5 (human)" "trunk ganglion" - "protein localization to actin filament bundle" + "postcranial axial skeletal system" "secretion by cell" - "heterobicyclic compound" + "protein localization to actin filament bundle" "epithelial cell of esophagus" + "heterobicyclic compound" "male sex differentiation" - "postcranial axial skeletal system" "dendritic cell differentiation" "respiratory system epithelium" "venous blood vessel development" @@ -7420,8 +7420,8 @@ "negative regulation of T cell cytokine production" "lateral mesoderm morphogenesis" "paraxial mesoderm morphogenesis" - "splenocyte" "heart ventricle wall" + "splenocyte" "adipocyte" "negative regulation of amino acid transport" "regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis" @@ -7448,8 +7448,8 @@ "carboxylic ester" "presumptive paraxial mesoderm" "maxillary process mesenchyme from neural crest" - "regulation of intracellular transport" "elliptic" + "regulation of intracellular transport" "cell proliferation involved in heart morphogenesis" "amino sugar biosynthetic process" "dense core granule" @@ -7479,8 +7479,8 @@ "muscle fibroblast" "negative regulation of colon smooth muscle contraction" "transitional myocyte of sinoatrial node" - "epithelium of biliary system" "optic cup morphogenesis involved in camera-type eye development" + "epithelium of biliary system" "female urethra development" "erythroid progenitor cell, mammalian" "midbrain-hindbrain boundary morphogenesis" @@ -7622,8 +7622,8 @@ "Aves" "epididymis" "Dipnotetrapodomorpha" - "negative regulation of syncytium formation by plasma membrane fusion" "myeloid leukocyte migration" + "negative regulation of syncytium formation by plasma membrane fusion" "cleavage stage" "neural keel" "male meiosis II" @@ -7639,8 +7639,8 @@ "Amoebozoa" "vertebral element" "negative regulation of biosynthetic process" - "positive regulation of phagocytosis" "respiratory system venous endothelium" + "positive regulation of phagocytosis" "brain vascular cell" "epithelial cell of skin gland" "positive regulation of formation of translation initiation ternary complex" @@ -7663,9 +7663,9 @@ "regulation of epithelial tube formation" "regulation of vacuole organization" "digestive tract development" + "thoracic vertebra pre-cartilage condensation" "exocytic vesicle membrane" "cardiac chamber formation" - "thoracic vertebra pre-cartilage condensation" "colon smooth muscle contraction" "ribonucleoprotein complex biogenesis" "Acipenserini" @@ -7673,8 +7673,8 @@ "submucosa of pylorus" "seminal vesicle fluid" "alpha-amino acid biosynthetic process" - "atypical epithelium" "future myelencephalon" + "atypical epithelium" "neck bone" "protein catabolic process" "wall of blood vessel" @@ -7706,9 +7706,9 @@ "lower region" "ventro-lateral region" "lower side" - "ventral side" "ventral margin" "dorsal margin" + "ventral side" "proximal-distal axis" "proximal side" "ventro-medial region" @@ -7780,8 +7780,8 @@ "upper side" "distal surface" "external side"@en - "medial margin" "medial side" + "medial margin" "anatomical plane" "distal region" "distal side" @@ -7794,8 +7794,6 @@ "two-dimensional spatial region"@en "centrally registered identifier registry"@en "identifier creating process"@en - "decreased size" - "increased size" "sequence_feature" "protein_coding" "organism" @@ -7804,6 +7802,8 @@ "Drosophila melanogaster protein" "object" "resilin (fruit fly)" + "decreased size" + "increased size" "abdominal sternite VII"@en "tentorio-premental muscle"@en "fronto-oral muscle"@en @@ -7818,17 +7818,17 @@ "subcostal vein of the insect wing"@en "insect leg muscle"@en "stipes"@en + "deflexed"@en "abdominal sternite I"@en + "axillary sclerite"@en "abdominal sternite VI"@en "flagellomere 2"@en - "axillary sclerite"@en - "postoccipitopremental muscle"@en "gena"@en + "postoccipitopremental muscle"@en "cranio-hypopharyngeal muscle"@en + "mesofurca"@en "cranio-labial muscle"@en - "deflexed"@en "basal mesocoxal conjunctiva"@en - "mesofurca"@en "anterior tentorial pit"@en "protarsomere II-protarsomere III conjunctiva"@en "dorsal longitudinal abdominal muscle"@en @@ -7850,8 +7850,8 @@ "basisternum"@en "placoid sensillum"@en "lateral clypeal tooth 2"@en - "abdominal tergite VIII-abdominal tergite IX conjunctiva"@en "protarsus"@en + "abdominal tergite VIII-abdominal tergite IX conjunctiva"@en "ovipositor"@en "tarsomere"@en "pleuron"@en @@ -7898,13 +7898,13 @@ "frontoclypeal sulcus"@en "profurca-occipital muscle"@en "carina of vertex"@en + "mesonoto-mesotrochantinal muscle"@en "protrochantin"@en "mesofemoral muscle"@en - "mesonoto-mesotrochantinal muscle"@en "lateral scapo-pedicellar muscle"@en "salivarium"@en - "setose cuticle"@en "noto-pleural conjunctiva"@en + "setose cuticle"@en "insect wing"@en "medial clypeal tooth"@en "maxillary palpomere I"@en @@ -7925,8 +7925,8 @@ "first maxillar palpopalpal muscle"@en "propleuron" "mesotarsomere V"@en - "insect mentum"@en "arolium"@en + "insect mentum"@en "maxillary palpomere"@en "apodeme"@en "intertarsomeral conjunctiva"@en @@ -7951,16 +7951,16 @@ "cardo-stipital conjunctiva"@en "mesonotum"@en "abdominal sternite V"@en + "insect external male genitalia"@en "insect abdomen"@en "cranio-mandibular muscle"@en "premento-palpal muscle"@en - "insect external male genitalia"@en "mesotarsomere IV-mesotarsomere V conjunctiva"@en - "metafurco-abdominal sternite muscle"@en "sensillum placodeum"@en "abdominal sternite VIII-abdominal sternite IX conjunctiva"@en "spermathecal gland"@en "femur"@en + "metafurco-abdominal sternite muscle"@en "gonocoxa IX"@en "posterior mesothoracic foramen"@en "mesonoto-mesopleural conjuntiva"@en @@ -7973,17 +7973,17 @@ "presternum"@en "insect ligament"@en "metasternum"@en - "palpifer"@en "abdomen with 7 sternites"@en + "palpifer"@en "gonapophysis"@en "stipito-lacinial conjunctiva"@en "mere"@en "insect abdominal segment VI"@en "mesocoxal-mesotrochanteral conjunctiva"@en + "mesonoto-metanotal muscle"@en "dorsal second axillary sclerite"@en "flagellomere 5-flagellomere 6 conjunctiva"@en "aedeagus"@en - "mesonoto-metanotal muscle"@en "trochantero-femoral conjunctiva"@en "dorsal tentorial arm"@en "ring shaped" @@ -8029,10 +8029,10 @@ "head margin at genoclypeal sulcus"@en "cranio-lacinial muscle"@en "right ventral conjunctiva of paramere"@en - "abdominal tergite III-abdominal tergite IV conjunctiva"@en "internal cranio-mandibular muscle"@en "cuticular fossa"@en "profemoral muscle"@en + "abdominal tergite III-abdominal tergite IV conjunctiva"@en "fronto-pedicellar muscle"@en "cuticular ridge"@en "third maxillar palpopalpal muscle"@en @@ -8168,15 +8168,15 @@ "anapleural sulcus"@en "postoccipital ridge"@en "frontal suture"@en - "fore wing"@en "gonocoxite"@en + "fore wing"@en "protarsomere II"@en "cercomere"@en "subgenal sulcus"@en "tarsus"@en "prophragma-tentorial muscle"@en - "distal carina of tergite VIII"@en "galea"@en + "distal carina of tergite VIII"@en "frontoclypeal ridge"@en "cranio-cardinal muscle"@en "left ventral conjunctiva of paramere"@en @@ -8189,27 +8189,27 @@ "insect abdominal segment II"@en "distance" "protarsomere I"@en - "metatarso-metapretarsal conjunctiva"@en "maxillary palpus with 4 palpomeres"@en + "metatarso-metapretarsal conjunctiva"@en "abdominal sternite"@en "cuticular sulcus"@en "profurco-mesofurcal muscle"@en "procoxa"@en "epistoepipharyngeal muscle"@en + "insect abdominal insect spiracle"@en "anteroexternal cranio-mandibular muscle"@en "basal wing conjunctiva" "premento-glossal muscle"@en - "insect abdominal insect spiracle"@en - "pronoto-mesopectal conjunctiva"@en "maxillary palpomere IV"@en + "pronoto-mesopectal conjunctiva"@en "tentorio-antennal muscle"@en - "phragma"@en "dorsal protibial cuticular tooth 4"@en + "phragma"@en "mesotarsomere III"@en - "pretarsal seta"@en "insect thoracic segment"@en "mesosterno-mesocoxal conjunctiva"@en "mental-premental conjunctiva"@en + "pretarsal seta"@en "stipito-galeal muscle"@en "sensillum trichodeum"@en "metapectus"@en @@ -8229,15 +8229,15 @@ "stridulatory file"@en "ventral second axillary sclerite"@en "pterothorax"@en - "insect ocellus"@en "insect appendage segment"@en + "insect ocellus"@en "mandibular molar lobe"@en "cuticular carina"@en "abdominal sternite IV-abdominal sternite V conjunctiva"@en "paraglossa"@en "abdominal sternite III"@en - "prepectus"@en "pronoto-mesonotal muscle"@en + "prepectus"@en "microreticulate"@en "decreased thickness" "insect abdominal segment X"@en @@ -8275,11 +8275,11 @@ "insect leg"@en "pretarsal muscle"@en "insect spiracle"@en - "palpifero-palpal conjunctiva"@en "protibial cuticular tooth"@en - "insect abdominal segment III"@en - "paraphyses"@en + "palpifero-palpal conjunctiva"@en "antenna with 9 antennomeres"@en + "paraphyses"@en + "insect abdominal segment III"@en "dorsal cervico-occipital muscle"@en "metatibio-metatarsal conjunctiva"@en "postoccipital sulcus"@en @@ -8306,14 +8306,14 @@ "postclypeus"@en "epistoma"@en "socket membrane"@en - "hypostomal bridge"@en "first axillary sclerite"@en + "hypostomal bridge"@en "insect cranio-maxillar muscle"@en "ventral conjunctiva of paramere"@en "jugal field of the insect wing"@en "torma"@en - "conical" "elastic cuticle"@en + "conical" "abdominal tergite III"@en "metatarsomere V"@en "cuticular fovea"@en @@ -8334,10 +8334,10 @@ "metanotum"@en "inferomedial tentorio-mandibular muscle"@en "genal margin"@en - "propleuro-prosternal conjunctiva"@en "posteroexternal cranio-mandibular muscle"@en - "metatarsomere IV"@en + "propleuro-prosternal conjunctiva"@en "premento-paraglossal muscle"@en + "metatarsomere IV"@en "metatibial muscle"@en "insect thoracic spiracle"@en "prescutum"@en @@ -8354,8 +8354,8 @@ "empodium"@en "metatarsomere IV-metatarsomere V conjunctiva"@en "cuticular scale"@en - "tracheal gill"@en "glossa"@en + "tracheal gill"@en "antennifer"@en "antennal foramen"@en "metatarsomere II"@en @@ -8368,14 +8368,14 @@ "interfurcal muscle"@en "abdominal sternite III-abdominal sternite IV conjunctiva"@en "metacoxa"@en - "prementum"@en "tergo-tergal muscle"@en + "prementum"@en "metanoto-metapleural conjunctiva"@en "profemur"@en "prothorax"@en "mesonoto-metanotal conjunctiva"@en - "clypeolabrum"@en "anterior metathoracic foramen"@en + "clypeolabrum"@en "ring sclerite"@en "scapus"@en "insect prothoracic segment"@en @@ -8384,8 +8384,8 @@ "abdominal sternite I-abdominal sternite II conjunctiva"@en "tentorio-paraglossal muscle"@en "cuticular suture"@en - "anal field of the insect wing"@en "metanoto-metatrochantinal muscle"@en + "anal field of the insect wing"@en "epipharynx"@en "protarsomere IV-protarsomere V conjunctiva"@en "coxal muscle"@en @@ -8411,8 +8411,6 @@ "basal metacoxal conjunctiva"@en "posterior tentorial pit"@en "oral foraminal conjunctiva"@en - "back"@en - "back" "stipito-galeal conjunctiva"@en "cuticular exocrine gland duct"@en "tibial cuticular tooth"@en @@ -8423,6 +8421,8 @@ "submentum"@en "unicellular ectodermal gland"@en "insect abdominal segment IX"@en + "back"@en + "back" "prophragma-cervical muscle"@en "propleuro-procoxal conjunctiva"@en "antennomere"@en @@ -8442,13 +8442,13 @@ "protarso-propretarsal conjunctiva"@en "abdominal tergite IX-abdominal tergite X conjunctiva"@en "spermatheca"@en + "abdomen with 8 sternites"@en "down"@en "down" - "abdomen with 8 sternites"@en - "protibio-protarsal conjunctiva"@en "labial palpomere I"@en - "occipital ridge"@en + "protibio-protarsal conjunctiva"@en "pronoto-occipital muscle"@en + "occipital ridge"@en "anterior mesothoracic foramen"@en "discrimen"@en "solid cuticular protrusion"@en @@ -8493,8 +8493,8 @@ "pretarsal claw"@en "metatrochantin"@en "cuticular spur"@en - "medial field of the insect wing"@en "ligula"@en + "medial field of the insect wing"@en "metatarsomere I"@en "conjunctival keel"@en "anterior tentorio-stipital muscle"@en @@ -8516,9 +8516,9 @@ "genital chamber"@en "poststernite"@en "pronoto-propleural conjunctiva"@en + "metaphragma"@en "coxa"@en "basal coxal conjunctiva"@en - "metaphragma"@en "flagellomere 2-flagellomere 3 conjunctiva"@en "furco-coxal muscle"@en "hypopharyngeomandibular muscle"@en @@ -8595,8 +8595,8 @@ "negative regulation of chromatin modification" "downregulation of chromatin assembly or disassembly" "syncitiotrophoblast" - "syntrophoblast" "syncitiotrophoblastus" + "syntrophoblast" "inhibition of neuropeptide-mediated retrograde trans-synaptic signaling" "negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling" "respiratory tract" @@ -8784,8 +8784,8 @@ "death" "sinew development" "kidney interstitium group" - "cavitated compound organs" "iris pigmented epithelium" + "cavitated compound organs" "alkali metal salts" "ectodermal gut development" "vasculature of skin" @@ -8839,13 +8839,13 @@ "bilirubin dianion" "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate" "bilirubin IXalpha" + "cytokine secretion during immune response" + "cytokine production during immune response" + "cytokine secretion involved in immune response" "sigmoid flexure" "pelvic colon" "colon sigmoideum" "sigmoid colon" - "cytokine secretion during immune response" - "cytokine production during immune response" - "cytokine secretion involved in immune response" "anorganische Verbindungen" "inorganic compounds" "inorganic molecular entities" @@ -9025,13 +9025,13 @@ "male genital secretion" "male genital fluid" "seminal fluid" + "eye pigment epithelium" "regulation of protein localisation in plasma membrane" "regulation of protein targeting to plasma membrane" "regulation of establishment of protein localization in plasma membrane" "regulation of protein-plasma membrane targeting" "regulation of establishment of protein localisation in plasma membrane" "regulation of establishment of protein localization to plasma membrane" - "eye pigment epithelium" "AER" "crista ectodermalis apicalis" "articulatio atlantooccipitalis" @@ -9233,10 +9233,10 @@ "regulation of collagen fibrillogenesis" "susceptibility to insect" "phosphorus molecular entities" - "ventral mandibular arch" - "ventral visceral arch 1" "somitomeric mesoderm" "somitomere" + "ventral mandibular arch" + "ventral visceral arch 1" "sulfate permease activity" "nephrogenesis" "cardiomyocyte generation" @@ -9280,8 +9280,8 @@ "paramesonephric duct of female" "fallopian tubes" "female paramesonephric duct" - "sodium channel auxiliary protein activity" "splanchnic mesoderm" + "sodium channel auxiliary protein activity" "negative regulation of establishment of protein localisation in plasma membrane" "negative regulation of establishment of protein localization to plasma membrane" "down-regulation of protein targeting to plasma membrane" @@ -9470,11 +9470,11 @@ "carbono" "carbon" "carbone" - "cilium cytoplasm" "ciliary cytoplasm" "microtubule-based flagellar cytoplasm" "cilial cytoplasm" "microtubule-based flagellum cytoplasm" + "cilium cytoplasm" "pleuroperitoneal channel" "a protein" "Protein" @@ -10064,17 +10064,17 @@ "DNase regulator" "deoxyribonuclease regulator" "intralobular ductule" - "blastosphere" "pancreatis dorsalis" + "blastosphere" "AV node cell differentiation" "pan-neural process" + "homoatomic molecules" + "homoatomic molecule" "oral region gland" "gland of oral opening" "oral cavity gland" "mouth gland" "gland of oral region" - "homoatomic molecules" - "homoatomic molecule" "regulation of presynapse organization and biogenesis" "chorda nephrogenica" "cell adhesion receptor regulator activity" @@ -10105,15 +10105,15 @@ "submucous layer of pharynx" "submucous coat of pharynx" "pharyngobasilar fascia" + "os penis/os clitoris" "renal arteries" "arteria renalis" - "os penis/os clitoris" "phosphate transport" "extraembryonic placenta" "maternal decidual layer" "maternal part of placenta" - "uterine decidua" "maternal placenta" + "uterine decidua" "placenta maternal decidual layer" "endometrium" "extraembryonic part of placenta" @@ -10245,15 +10245,11 @@ "NH(2-)" "heart Purkinje fiber" "hypodermal cell differentiation" - "pelvic vein" "IL7R" + "pelvic vein" "body growth" "body segment" "main body segment" - "developmental timing" - "pericardium visceral mesothelium" - "epicardium" - "single-organism reproductive behavior" "tunica muscularis" "muscularis externa" "muscular coat" @@ -10261,6 +10257,10 @@ "muscularis propria" "tunica externa" "transverse muscular fibers" + "developmental timing" + "pericardium visceral mesothelium" + "epicardium" + "single-organism reproductive behavior" "food additives" "Nemata" "nematodes" @@ -10331,13 +10331,13 @@ "Glykan" "protein transport chaperone" "protein carrier activity" + "primordial pancreas" + "pancreatic endoderm" + "pancreatic anlage" "regulation of postsynapse organization and biogenesis" "sensory transduction of electrical stimulus during perception of pain" "sensory detection of electrical stimulus during perception of pain" "detection of electrical stimulus during sensory perception of pain" - "primordial pancreas" - "pancreatic endoderm" - "pancreatic anlage" "hollow bone" "cell proliferation" "hexose transport" @@ -10388,6 +10388,8 @@ "pars ascendens aortae" "aorta ascendens" "positive regulation of cell movement" + "hydroxy/aromatic amino acid permease activity" + "general amino acid permease activity" "group V elements" "nitrogenoideos" "pnictogene" @@ -10395,8 +10397,6 @@ "pnictogenes" "nitrogenoides" "CN V development" - "hydroxy/aromatic amino acid permease activity" - "general amino acid permease activity" "ciliated neck segment" "Netzhaut" "retinas" @@ -10860,9 +10860,9 @@ "upper body connective tissue" "extraembryonic structures" "extraembryonic tissue" - "Chemische Substanz" "iecur" "jecur" + "Chemische Substanz" "regulation of protein complex assembly" "basement lamina" "basal lamina" @@ -11133,28 +11133,28 @@ "glans clitoris" "Eurypterygii" "peritoneal component" - "up-regulation of cytokine production during immune response" - "positive regulation of cytokine production during immune response" - "upregulation of cytokine production during immune response" - "up regulation of cytokine production during immune response" "downregulation of generation of action potential" "inhibition of generation of action potential" "down regulation of generation of action potential" "negative regulation of generation of action potential" "down-regulation of generation of action potential" + "up-regulation of cytokine production during immune response" + "positive regulation of cytokine production during immune response" + "upregulation of cytokine production during immune response" + "up regulation of cytokine production during immune response" "tunica externa vasorum" "external coat" "tunica adventitia vasorum" "pulmonary arterial subtree" "arteria pulmonalis" "truncus pulmonalis" + "E.coli metabolites" + "E.coli metabolite" + "Escherichia coli metabolites" "glycosaminoglycans" "glicosaminoglicano" "glycosaminoglycane" "Glykosaminoglykan" - "E.coli metabolites" - "E.coli metabolite" - "Escherichia coli metabolites" "lung mesothelium" "lung pleura" "pulmonary pleura" @@ -11189,10 +11189,10 @@ "stroma ovarii" "nephrogenic tissue" "microcirculatory vessels" + "nephric cord" "scapular girdle" "cingulum pectorale" "pectoral girdle" - "nephric cord" "cyclic compounds" "glandula" "Druese" @@ -11322,8 +11322,8 @@ "vena testicularis sinistra" "primary carboxamide" "carboxamides" - "fungal metabolites" "vacuolar carboxypeptidase Y" + "fungal metabolites" "pectoral region" "pectoral girdle" "whole blood" @@ -11483,11 +11483,11 @@ "antibacterial peptide activity" "dense core granule clustering" "Struthio camelus domesticus" + "nucleoside residues" "neutral molecular compounds" "Molekuel" "molecules" "molecula" - "nucleoside residues" "pelvic girdle" "metal elements" "metals" @@ -11710,12 +11710,12 @@ "pronormoblast" "primary amino compounds" "Acanthomorpha" - "developmental structure" - "developmental tissue" - "developing structure" "placental vasculature" "MHB maturation" "isthmus maturation" + "developmental structure" + "developmental tissue" + "developing structure" "spermatic chord" "funiculus spermaticus" "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" @@ -11767,8 +11767,8 @@ "cholinergic agent" "cholinomimetic" "cholinergic drugs" - "smooth muscle of cloaca" "smooth muscle plasticity" + "smooth muscle of cloaca" "T-lymphocyte secretory granule maturation" "T cell secretory granule organization and biogenesis" "primitive ectoderm" @@ -12178,6 +12178,8 @@ "atrioventricular canal cushion" "gonads" "regulation of Golgi organization and biogenesis" + "peptide hormones" + "polypeptide hormone" "H2SO4" "Acide sulfurique" "[SO2(OH)2]" @@ -12186,8 +12188,6 @@ "Schwefelsaeureloesungen" "Acidum sulfuricum" "sulphuric acid" - "peptide hormones" - "polypeptide hormone" "inhibition of hemolymph circulation" "negative regulation of hemolymph circulation" "downregulation of hemolymph circulation" @@ -12228,8 +12228,8 @@ "Wasserstoff" "hydrogen" "hidrogeno" - "1H" "H" + "1H" "Agnatha" "T cell differentiation during immune response" "T-cell differentiation during immune response" @@ -12379,10 +12379,10 @@ "vitelline membrane" "zona striata" "positive regulation of cytoskeleton organization and biogenesis" - "trabecular vein" "MAL" "Lyt-2" "Lyt2" + "trabecular vein" "renal or urinary system" "renal/urinary system" "blocked" @@ -12448,10 +12448,10 @@ "body surface" "external covering of organism" "integumentum commune" + "CVS" "mitotic nuclear envelope degradation" "mitotic nuclear envelope catabolism" "mitotic nuclear envelope disassembly" - "CVS" "muscle element" "muscle" "acides nucleiques" @@ -12838,8 +12838,8 @@ "heart endocardial tissue" "fermions" "carbon group molecular entities" - "homoacetate catabolic process" "organochalcogen compounds" + "homoacetate catabolic process" "reproductive system secretion" "genital secretion" "reproductive system fluid" @@ -13049,9 +13049,9 @@ "essential metabolites" "regulation of signaling (initiator) caspase activity of metanephric collecting duct development" "nuclease regulator activity" + "Cdh5" "zygomaticotemporal" "zygomaticotemporal branch" - "Cdh5" "vertebral region" "dorsal spine" "spinal column" @@ -13178,9 +13178,9 @@ "branchial arch 4 mesenchyme from head mesenchyme" "sulfuric acid derivative" "sulphates" + "atrial myocardium" "amino acid residue" "amino-acid residues" - "atrial myocardium" "islets of Langerhans part of pancreas" "endocrine part of pancreas" "sperm activation" @@ -13201,12 +13201,12 @@ "human xenobiotic metabolites" "foramen vertebrale" "subatomic particles" + "Komplexauge" "zusammengesetztes Auge" "adult compound eye" "insect eye" "faceted eye" "Facettenauge" - "Komplexauge" "anatomical cluster" "organic cations" "Osteichthyes" @@ -13223,8 +13223,8 @@ "eye" "globe" "plasma membrane organization and biogenesis" - "zygote" "fertilized egg stage" + "zygote" "one-cell stage" "zygotum" "N-acyl-hexosamines" @@ -13513,6 +13513,9 @@ "coronal section" "cross-section" "cross-section" + "located sequence feature" + "CG15920" + "resilin" "tiny" "reduced" "small" @@ -13521,9 +13524,6 @@ "expanded" "big" "great" - "located sequence feature" - "CG15920" - "resilin" "slender" "thin" "thick" @@ -13817,11 +13817,11 @@ "primary cilium" "regulation of cardiac muscle cell apoptosis" "inhibition of cell differentiation" - "stimulation of cardiac muscle fiber development" - "activation of cardiac muscle fiber development" "inhibition of leukocyte adhesion" "inhibition of leukocyte cell-cell adhesion" "inhibition of leukocyte cell adhesion" + "stimulation of cardiac muscle fiber development" + "activation of cardiac muscle fiber development" "activation of fibril organization" "activation of fibril organisation" "hyaluronic acid secreting cell" @@ -13878,8 +13878,8 @@ "stimulation of dendritic cell cytokine production" "activation of exosomal protein secretion" "up regulation of exosomal protein secretion" - "activation of exosomal secretion" "activation of secretion of exosome" + "activation of exosomal secretion" "activation of exosomal secretory pathway" "positive regulation of exosomal protein secretion" "upregulation of exosomal protein secretion" @@ -14153,8 +14153,8 @@ "apoptosis" "activation of apoptosis" "type I programmed cell death" - "apoptotic program" "apoptosis signaling" + "apoptotic program" "positive regulation of neurite growth" "positive regulation of neurite biosynthesis" "positive regulation of neurite formation" @@ -14348,8 +14348,8 @@ "buccal gland" "stimulation of neurological process" "activation of neurological process" - "inhibition of fat cell differentiation" "spinal cord basal plate" + "inhibition of fat cell differentiation" "early paramesonephric duct" "stimulation of amino acid metabolic process" "activation of amino acid metabolic process" @@ -14384,9 +14384,9 @@ "down-regulation of epitheliocyte apoptosis" "inhibition of epitheliocyte apoptotic process" "downregulation of epitheliocyte apoptosis" + "negative regulation of epithelial cell apoptosis" "downregulation of epithelial cell apoptosis" "inhibition of epithelial cell apoptosis" - "negative regulation of epithelial cell apoptosis" "inhibition of epithelial cell apoptotic process" "septum inferius development" "inhibition of endodermal cell differentiation" @@ -14697,11 +14697,11 @@ "activation of neuroblast proliferation" "stimulation of neuroblast proliferation" "male human body" + "inhibition of DNA fragmentation involved in apoptotic nuclear change" "inhibition of DNA catabolic process during apoptosis" "inhibition of DNA catabolism during apoptosis" "inhibition of endonucleolytic DNA catabolic process involved in apoptosis" "inhibition of apoptotic DNA fragmentation" - "inhibition of DNA fragmentation involved in apoptotic nuclear change" "inhibition of cell proliferation" "inhibition of cardiac muscle fiber development" "stimulation of leukocyte migration" @@ -14861,11 +14861,11 @@ "lymphocyte apoptosis" "positive regulation of type B pancreatic cell apoptosis" "bladder" + "inhibition of neuronal action potential" "activation of cytokine production during immune response" "positive regulation of cytokine secretion involved in immune response" "positive regulation of cytokine biosynthetic process involved in immune response" "stimulation of cytokine production during immune response" - "inhibition of neuronal action potential" "regulation of cyclin catabolic process" "regulation of cyclin degradation" "regulation of cyclin catabolism" @@ -15151,10 +15151,10 @@ "activation of motor neuron migration" "other moved mouth parts" "mouth part movement" - "inhibition of mitotic nuclear envelope disassembly" "inhibition of mitotic nuclear envelope degradation" "inhibition of mitotic nuclear envelope catabolism" "inhibition of mitotic nuclear envelope breakdown" + "inhibition of mitotic nuclear envelope disassembly" "activation of cardiac myofibril morphogenesis" "activation of cardiac myofibril development" "activation of cardiac myofibril assembly" @@ -15435,9 +15435,9 @@ "inhibition of blood circulation" "activation of lipid catabolic process" "stimulation of lipid catabolic process" + "axonal protein transport" "stimulation of muscle development" "activation of muscle development" - "axonal protein transport" "activation of establishment of T-cell polarity" "activation of T cell polarization" "activation of T lymphocyte polarization" @@ -16068,8 +16068,8 @@ "nape" "salpinx" "salpinges" - "sodium/potassium transport" "visceral mesoderm" + "sodium/potassium transport" "plasma" "portion of plasma" "primitive nephron" @@ -16096,13 +16096,13 @@ "urinary system development" "carotid artery" "renal tubule" - "MTg" - "tegmentum" "blebbing" "membrane blebbing" + "MTg" + "tegmentum" "ureteric bud mesenchymal cell proliferation" - "female meiotic division" "female meiosis" + "female meiotic division" "nitrogen compound biosynthesis" "nitrogen compound synthesis" "nitrogen compound formation" @@ -16203,8 +16203,8 @@ "segment of midbrain" "mesomere" "midbrain segment" - "girdle" "girdle region" + "girdle" "heparin-binding growth factor 8 (human)" "HBGF-8 (human)" "regulation of retinal cell programmed cell death" @@ -16555,9 +16555,9 @@ "endothelium of capillary of apparatus respiratorius" "respiratory system endothelium of capillary vessel" "capillary endothelium of apparatus respiratorius" + "respiratory system capillary vessel endothelium" "blood capillary endothelium of respiratory system" "apparatus respiratorius blood capillary endothelium" - "respiratory system capillary vessel endothelium" "apparatus respiratorius endothelium of capillary" "respiratory system blood capillary endothelium" "apparatus respiratorius capillary vessel endothelium" @@ -16912,13 +16912,13 @@ "anterior gray column of spinal cord" "ventral gray matter of spinal cord" "ventral horn spinal cord" + "entire skin" + "skin organ" "downregulation of endothelial cell proliferation" "down-regulation of endothelial cell proliferation" "down regulation of endothelial cell proliferation" - "entire skin" - "skin organ" - "vesica urinaria" "mesenchymal stem cell of adipose" + "vesica urinaria" "post-Golgi transport" "larval head sense organ" "trophectoderm cell" @@ -16964,7 +16964,6 @@ "stroma of kidney" "interstitial tissue of kidney" "renal interstitial tissue" - "cavitated organ" "iris epithelial tissue" "pigmented epithelium of iris" "epithelial tissue of iris" @@ -16972,6 +16971,7 @@ "iris epithelium" "epithelium of iris" "epithelium pigmentosum (iris)" + "cavitated organ" "regulation of haemopoietic progenitor cell differentiation" "regulation of hemopoietic progenitor cell differentiation" "regulation of haematopoietic progenitor cell differentiation" @@ -16982,10 +16982,10 @@ "CD56 (mouse)" "NCAM-1 (mouse)" "N-CAM-1 (mouse)" - "smooth muscle tissue of gastrointestinal system" "down regulation of microtubule nucleation" "downregulation of microtubule nucleation" "down-regulation of microtubule nucleation" + "smooth muscle tissue of gastrointestinal system" "down regulation of epithelial tube formation" "down-regulation of epithelial tube formation" "downregulation of epithelial tube formation" @@ -17109,6 +17109,7 @@ "glycogen catabolism" "glycogen degradation" "glycogenolysis" + "primitive right ventricle endocardium" "respiratory system blood capillary" "apparatus respiratorius blood capillary" "apparatus respiratorius capillary vessel" @@ -17120,7 +17121,6 @@ "capillary of apparatus respiratorius" "blood capillary of apparatus respiratorius" "apparatus respiratorius capillary" - "primitive right ventricle endocardium" "liver and biliary system" "hepaticobiliary system" "cephalic muscle" @@ -17512,18 +17512,18 @@ "pelvic girdle plus posterior limb or fin" "pelvic girdle plus pelvic limb or fin" "pelvic appendage/girdle complex" - "molecular entity" "nucleate RBC maturation" "nucleate red blood cell maturation" + "molecular entity" "serosa of infundibulum of fallopian tube" "serosa of infundibulum of oviduct" - "regulation of small molecule metabolism" "TfR1 (human)" "CD71 (human)" "hTFRC" "T9 (human)" "Trfr (human)" "TfR (human)" + "regulation of small molecule metabolism" "output neuron" "neural tube lateral wall sulcus limitans" "regulation of enzyme activity" @@ -17587,11 +17587,11 @@ "neural tube ependymal layer" "neural tube ventricular zone" "presumptive rhombencephalon" - "notochord fluid" - "portion of notochordal fluid" "upregulation of cell-cell adhesion" "up regulation of cell-cell adhesion" "up-regulation of cell-cell adhesion" + "notochord fluid" + "portion of notochordal fluid" "cell of epidermis" "negative regulation of mitosis" "down regulation of mitosis" @@ -17720,8 +17720,8 @@ "visceral peritoneum of uterus" "serous membrane of uterus" "perimetrium" - "serous coat of uterus" "tunica serosa uteri" + "serous coat of uterus" "tunica serosa (perimetrium)" "chief pancreatic duct" "duct of Wirsung" @@ -17765,17 +17765,17 @@ "carrier activity" "permease activity" "active carrier activity" - "ureteral smooth muscle" - "ureteral smooth muscle layer" + "pharynx skeletal muscle" + "pharynx skeletal muscle tissue" + "skeletal muscle tissue of pharynx" "hydroxidotrioxidosulfate(1-)" "hydrogensulfate" "hydrogen(tetraoxidosulfate)(1-)" "hydrogentetraoxosulfate(VI)" "hydrogensulfate(1-)" "hydrogentetraoxosulfate(1-)" - "pharynx skeletal muscle" - "pharynx skeletal muscle tissue" - "skeletal muscle tissue of pharynx" + "ureteral smooth muscle" + "ureteral smooth muscle layer" "muscular layer of anal canal" "anal muscularis propria" "muscularis externa of anal canal" @@ -17905,8 +17905,8 @@ "ductus choledochus (biliaris) mucosa of organ" "ductus choledochus (biliaris) mucosa" "ductus choledochus (biliaris) organ mucosa" - "organ mucosa of common bile duct" "common bile duct mucosa" + "organ mucosa of common bile duct" "mucosa of organ of ductus choledochus (biliaris)" "mucosa of ductus choledochus (biliaris)" "steroid metabolism" @@ -18268,8 +18268,8 @@ "down-regulation of response to external stimulus" "down regulation of response to external stimulus" "pars membranacea (septi interventricularis)" - "pars membranacea septi interventricularis" "membranous part of interventricular septum" + "pars membranacea septi interventricularis" "membranous part interventricular septum" "membranous interventricular septum" "cardiac ventricular membranous septum" @@ -18300,12 +18300,12 @@ "downregulation of physiological defense response to insect" "down regulation of physiological defense response to insect" "downregulation of defense response to insect" - "ventral pharyngeal arch 1" "cranial paraxial mesoderm" "cranial paraxial mesenchyme" "cephalic paraxial mesoderm" "head paraxial mesenchyme" "cephalic paraxial mesenchyme" + "ventral pharyngeal arch 1" "polysaccharide catabolism" "polysaccharide degradation" "polysaccharide breakdown" @@ -18319,10 +18319,10 @@ "cardiac precursor cell differentiation" "cardioblast cell differentiation" "venule of small intestine" - "vertebra of thorax" "thorax vertebra" "vertebra thoracica" "dorsal vertebra" + "vertebra of thorax" "mesonephros pattern specification" "mucous membrane of gall bladder" "gall bladder mucous membrane" @@ -18359,11 +18359,6 @@ "arteria ductus deferentis" "vas deferens artery" "artery of ductus deferens" - "up-regulation of cardiac muscle fiber development" - "positive regulation of cardiac muscle fibre development" - "positive regulation of heart muscle fiber development" - "up regulation of cardiac muscle fiber development" - "upregulation of cardiac muscle fiber development" "down regulation of leukocyte adhesion" "downregulation of leukocyte cell-cell adhesion" "downregulation of leukocyte adhesion" @@ -18375,6 +18370,11 @@ "down-regulation of leukocyte adhesion" "negative regulation of leukocyte cell adhesion" "down-regulation of leukocyte cell-cell adhesion" + "up-regulation of cardiac muscle fiber development" + "positive regulation of cardiac muscle fibre development" + "positive regulation of heart muscle fiber development" + "up regulation of cardiac muscle fiber development" + "upregulation of cardiac muscle fiber development" "AV node cell to bundle of His cell signalling" "atrioventricular node to bundle of His cell signaling" "endothelium of endocardium" @@ -18420,10 +18420,10 @@ "tetrapyrroles" "microtubulus" "microtubuli" + "anterior/posterior pattern specification involved in pronephric kidney development" "portion of excreted substance" "excreted substance" "waste substance" - "anterior/posterior pattern specification involved in pronephric kidney development" "negative regulation of cellular anabolism" "downregulation of cellular biosynthetic process" "down regulation of cellular biosynthetic process" @@ -18450,6 +18450,7 @@ "stratum musculosum panniculi adiposi telae subcutaneae" "muscle layer in fatty layer of subcutaneous tissue" "lumen of rectum" + "inner layer of lateral plate mesoderm" "down regulation of RBC apoptotic process" "down regulation of red blood cell apoptotic process" "down-regulation of red blood cell apoptotic process" @@ -18462,7 +18463,6 @@ "down-regulation of erythrocyte apoptotic process" "negative regulation of red blood cell apoptotic process" "sodium transport" - "inner layer of lateral plate mesoderm" "down-regulation of protein localization in plasma membrane" "down-regulation of protein localisation in plasma membrane" "down regulation of protein localisation in plasma membrane" @@ -18485,11 +18485,11 @@ "ascomycetes" "sac fungi" "broad uterine ligament" - "endometrium stroma" - "stroma of endometrium" "cellular membrane organization" "membrane organisation" "cellular membrane organisation" + "endometrium stroma" + "stroma of endometrium" "downregulation of catabolic process" "negative regulation of catabolism" "negative regulation of breakdown" @@ -18811,8 +18811,8 @@ "levarterenol catabolism" "levarterenol catabolic process" "norepinephrine breakdown" - "norepinephrine catabolism" "noradrenaline catabolism" + "norepinephrine catabolism" "noradrenaline catabolic process" "bilirubin" "3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" @@ -19110,7 +19110,6 @@ "arteriole of villus of small intestine" "arteriole of small intestine" "regulation of sarcomere organisation" - "anal region skeletal muscle tissue" "anal triangle skeletal muscle tissue" "anal part of perineum skeletal muscle tissue" "skeletal muscle tissue of anal region" @@ -19121,13 +19120,14 @@ "skeletal muscle tissue of anal triangle" "skeletal muscle of anal region" "anal triangle skeletal muscle" + "anal region skeletal muscle tissue" "lower jaw skeleton" "reagent" + "regulation of progression through mitotic cell cycle" "mitotic cell cycle regulation" "modulation of mitotic cell cycle progression" "regulation of mitotic cell cycle progression" "mitotic cell cycle modulation" - "regulation of progression through mitotic cell cycle" "up regulation of protein localization to plasma membrane" "up regulation of protein localization in plasma membrane" "up-regulation of protein localisation in plasma membrane" @@ -19395,11 +19395,11 @@ "up-regulation of acetate catabolic process" "upregulation of acetate catabolic process" "microfilament" - "tegmentum of midbrain" - "tegmentum mesencephali" "plasma membrane bleb assembly" "plasma membrane blebbing" "cell blebbing" + "tegmentum of midbrain" + "tegmentum mesencephali" "regulation of phosphate membrane transport" "thorax blood vessel" "blood vessel of thorax" @@ -19675,8 +19675,8 @@ "response to organic cyclic substance" "muscle of heart" "heart myocardium" - "air space of bone" "fruit fly" + "air space of bone" "segment of spinal cord" "axial part of spinal cord" "axial regional part of spinal cord" @@ -19698,6 +19698,11 @@ "baker's yeast" "rectum mesentery" "vascular smooth muscle cell migration" + "chemical entity" + "downregulation of amino acid metabolic process" + "down-regulation of amino acid metabolic process" + "negative regulation of amino acid metabolism" + "down regulation of amino acid metabolic process" "smooth muscle tissue of spleen" "smooth muscle of spleen" "spleen involuntary muscle" @@ -19705,11 +19710,6 @@ "spleen non-striated muscle" "involuntary muscle of spleen" "non-striated muscle of spleen" - "chemical entity" - "downregulation of amino acid metabolic process" - "down-regulation of amino acid metabolic process" - "negative regulation of amino acid metabolism" - "down regulation of amino acid metabolic process" "brachiocephalic trunk" "truncus brachiocephalicus" "innominate artery" @@ -19788,8 +19788,8 @@ "bladder mucous membrane" "tunica mucosa vesicae urinariae" "mucosa of bladder" - "urinary bladder mucous membrane" "mucous membrane of urinary bladder" + "urinary bladder mucous membrane" "urinary bladder mucosa" "tunica mucosa vesicae" "bladder mucosa" @@ -19818,12 +19818,12 @@ "roof of oral cavity" "roof of buccal cavity" "Lamé curve" - "pancreatic alpha cell development" "noradrenaline metabolic process" "levarterenol metabolic process" "norepinephrine metabolism" "levarterenol metabolism" "noradrenaline metabolism" + "pancreatic alpha cell development" "behaviour" "behavior" "heterocycle metabolism" @@ -20041,10 +20041,10 @@ "up-regulation of neuron maturation" "aldohexose" "ammonium ion metabolism" - "regulation of branching involved in blood vessel morphogenesis" "glandulae oesophageae" "mucous gland of submucosa of esophagus" "esophageal gland" + "regulation of branching involved in blood vessel morphogenesis" "generation of spermatozoa" "positive regulation of synapse biogenesis" "positive regulation of synaptogenesis" @@ -20303,12 +20303,12 @@ "up-regulation of translation initiation in response to stress" "up regulation of translation initiation in response to stress" "upregulation of translation initiation in response to stress" + "skull orifice" + "cranial orifice" "uterine glands set development" "endometrial gland development" "uterine glands development" "endometrium gland development" - "skull orifice" - "cranial orifice" "peritoneum mesothelium" "mesothelium of peritoneum" "mesothelium of peritoneal component" @@ -20360,13 +20360,13 @@ "upregulation of neurological process" "up regulation of neurological process" "positive regulation of neurological system process" + "basal plate" + "basal plate of neural tube" "down-regulation of fat cell differentiation" "negative regulation of adipocyte cell differentiation" "downregulation of fat cell differentiation" "negative regulation of adipocyte differentiation" "down regulation of fat cell differentiation" - "basal plate" - "basal plate of neural tube" "response to ammonia" "ductus paramesonephricus" "Müllerian duct" @@ -20702,14 +20702,14 @@ "bowel non-striated muscle" "non-striated muscle of bowel" "bowel involuntary muscle" - "intestine non-striated muscle" "smooth muscle of bowel" + "intestine non-striated muscle" "involuntary muscle of intestine" - "mesenchyme condensation" "apparatus respiratorius vein" "vein of apparatus respiratorius" "respiratory system vein" "vein of respiratory system" + "mesenchyme condensation" "peritoneal cavity lining development" "heart cone formation" "uterine endothelial cell" @@ -20742,6 +20742,8 @@ "cellular amide metabolic process" "cilial transition zone" "cilium transition zone" + "hepatic stroma" + "stroma of liver" "nervus maxillaris (Vb; V2)" "maxillary division [V2]" "second division of trigeminal nerve" @@ -20755,8 +20757,6 @@ "maxillary division of trigeminal nerve (Vb; V2)" "nervus maxillaris [v2]" "second division of fifth cranial nerve" - "hepatic stroma" - "stroma of liver" "spermiogenesis" "spermatid cell development" "central nervous system ganglion" @@ -20789,9 +20789,12 @@ "endochondral replacement element" "axial subdivision of organism" "spermatogonial cell" + "sphenoid element" + "tunica muscularis" + "muscular layer" + "muscularis layer" "temporal regulation of development" "heterochronic regulation of development" - "sphenoid element" "visceral lamina of serous pericardium" "visceral layer of serous pericardium" "serous visceral pericardium" @@ -20799,9 +20802,6 @@ "lamina visceralis pericardii serosi" "reproductive behaviour" "reproductive behavior in a multicellular organism" - "tunica muscularis" - "muscular layer" - "muscularis layer" "nematodes" "roundworm" "nematode" @@ -20927,11 +20927,11 @@ "down regulation of biological process" "negative regulation of physiological process" "down-regulation of biological process" + "pelvic/pectoral appendage" "girdle-associated appendage" "pectoral or pelvic appendage" "limb or fin" "limb/fin" - "pelvic/pectoral appendage" "cardiac muscle progenitor cell" "cardiomyocyte progenitor cell" "visceral wall of serous membrane" @@ -20941,8 +20941,8 @@ "cellular degradation" "cellular catabolism" "cellular breakdown" - "torso portion of connective tissue" "trunk portion of connective tissue" + "torso portion of connective tissue" "torso textus connectivus" "portion of connective tissue of torso" "textus connectivus of torso" @@ -20952,6 +20952,8 @@ "textus connectivus of trunk" "trunk textus connectivus" "torso connective tissue" + "polysaccharides" + "Polysaccharide" "down-regulation of protein localization in nucleolus" "down regulation of protein localisation in nucleolus" "down-regulation of protein localisation in nucleolus" @@ -20967,16 +20969,14 @@ "negative regulation of protein localisation to nucleolus" "downregulation of protein localization to nucleolus" "down regulation of protein localisation to nucleolus" - "polysaccharides" - "Polysaccharide" "regulation of photoreceptor differentiation" + "pancreatic primordium" "regulation of postsynapse structure" "regulation of postsynapse organisation" "pancreatic delta cell development" "perception of pain, sensory transduction of electrical stimulus" "perception of pain, detection of electrical stimulus" "perception of pain, sensory detection of electrical stimulus" - "pancreatic primordium" "pneumatic bone" "os pneumaticum" "pharynx epithelial tissue" @@ -21006,8 +21006,8 @@ "up regulation of protein localization in membrane" "upregulation of protein localization to membrane" "up-regulation of protein localisation in membrane" - "up-regulation of oogenesis" "up regulation of ovum development" + "up-regulation of oogenesis" "up-regulation of ovum development" "positive regulation of ovum development" "upregulation of ovum development" @@ -21103,10 +21103,10 @@ "positive regulation of cell locomotion" "pleuroperitoneal fold" "pleuroperitoneal membranes" + "amino acid permease activity" "pnictogens" "cranial nerve V development" "cranial nerve 5 development" - "amino acid permease activity" "pronephric tubule" "inner layer of eyeball" "retina of camera-type eye" @@ -21203,8 +21203,8 @@ "nucleus positioning" "nuclear positioning" "tela submucosa vesicae urinariae" - "submucosa of bladder" "urinary bladder submucosa" + "submucosa of bladder" "tela submucosa vesicae" "tela submucosa (vesica urinaria)" "bladder submucosa" @@ -21305,10 +21305,10 @@ "upregulation of syngamy" "upregulation of fertilization" "neuroglial cell" - "hepatic vasculature" "regulation of mitotic nuclear envelope breakdown" "regulation of mitotic nuclear envelope catabolism" "regulation of mitotic nuclear envelope degradation" + "hepatic vasculature" "positive regulation of body size" "positive regulation of body growth" "negative regulation of cytokine synthesis" @@ -21323,7 +21323,6 @@ "down-regulation of cytokine biosynthetic process" "perception of sound" "hearing" - "postnatal organism" "muscle layer of fallopian tube" "muscle layer of oviduct" "tunica muscularis tubae uterinae" @@ -21333,6 +21332,7 @@ "muscle layer of uterine tube" "uterine tubal muscularis" "tunica muscularis (Tuba uterina)" + "postnatal organism" "negative regulation of adipose cell proliferation" "down-regulation of fat cell proliferation" "negative regulation of adipocyte proliferation" @@ -21582,9 +21582,9 @@ "downregulation of leukocyte migration" "down regulation of leukocyte migration" "down-regulation of leukocyte migration" - "stationary movement" "heart or heart like organ" "cardiac pump" + "stationary movement" "presumptive atrium heart tube" "primordial cardiac atrium" "primordial atrium" @@ -21612,8 +21612,8 @@ "down regulation of photoreceptor differentiation" "right ventricle lumen" "right ventricular cavity" - "pancreatic buds" "pancreatic bud" + "pancreatic buds" "ventricular trabecular myocardium" "trabecular cardiac ventricle muscle" "myocardium of region of ventricle" @@ -21670,13 +21670,13 @@ "gray matter layer of neuraxis" "CNS grey matter layer" "parietal wall of serous membrane" - "adult aorta tunica intima" "tunica intima of dorsal aorta" "tunica intima of adult aorta" "dorsal aorta tunica intima" "tunica intima of aorta" "tunica intima of trunk of aortic tree" "trunk of aortic tree tunica intima" + "adult aorta tunica intima" "regulation of pancreatic beta cell apoptosis" "regulation of pancreatic B cell apoptosis" "female germ-line stem cell renewal" @@ -21879,8 +21879,8 @@ "hydrogentrioxocarbonate(1-)" "hydrogencarbonate(1-)" "hydrogen(trioxidocarbonate)(1-)" - "humor aquosus" "aqueous humour" + "humor aquosus" "aqueous humor" "upregulation of cell maturation" "up-regulation of cell maturation" @@ -21944,9 +21944,9 @@ "extracellular matrix organisation involved in endocardium development" "cavitas cranii" "somatosensory system development" - "chromosome division" "tail vertebra element" "caudal vertebra element" + "chromosome division" "neural tube morphogenesis" "neurulation" "regulation of pancreatic beta cell development" @@ -22420,10 +22420,10 @@ "base" "connective tissue of lung" "pulmonary interstitium" + "Wolffian body morphogenesis" "atrial myocardium morphogenesis" "cardiac atrium muscle morphogenesis" "atrial heart muscle morphogenesis" - "Wolffian body morphogenesis" "airway epithelial cell" "down regulation of DNA degradation" "down-regulation of DNA breakdown" @@ -22472,8 +22472,8 @@ "Golgi apparatus localization" "establishment and maintenance of Golgi localization" "SA nodal myocyte" - "sinuatrial node myocyte" "sinoatrial node myocyte" + "sinuatrial node myocyte" "SA node cardiac muscle cell" "sinoatrial node cell" "indole derivative catabolism" @@ -22738,14 +22738,14 @@ "positive regulation of leucocyte activation" "upregulation of leukocyte activation" "positive regulation of immune cell activation" + "splanchnocranium cartilage" + "pharyngeal arch cartilages" "oesophagus secretion" "gullet secretion" "esophageal secretion" "secretion of oesophagus" "secretion of gullet" "secretion of esophagus" - "splanchnocranium cartilage" - "pharyngeal arch cartilages" "upregulation of gonadogenesis" "positive regulation of gonadogenesis" "up-regulation of gonadogenesis" @@ -22828,8 +22828,8 @@ "down-regulation of epidermis development" "downregulation of epidermis development" "down regulation of epidermis development" - "neurogenic placodes" "myeloid leucocyte activation" + "neurogenic placodes" "downregulation of RNA metabolic process" "down-regulation of RNA metabolic process" "down regulation of RNA metabolic process" @@ -23005,12 +23005,12 @@ "connective tissue of abdominal segment of trunk" "textus connectivus of abdominal segment of trunk" "abdominal segment of trunk textus connectivus" + "ocular primordium" "occular primordium" "optic primordium" "optic placode of camera-type eye" "eye placode" "optic placode" - "ocular primordium" "iris muscle" "iris muscle organ" "muscle organ of iris" @@ -23040,8 +23040,8 @@ "lip zone of skin" "lip skin" "zone of skin of lip" - "cardiac vasculature" "trophectoderm cell differentiation" + "cardiac vasculature" "epithelium of efferent ductule of testis" "nucleon" "acinus of serous gland" @@ -23053,13 +23053,13 @@ "downregulation of neuronal action potential" "down regulation of neuronal action potential" "urethral orifice" - "tunica adventitia" - "tunica adventitia of vessel" - "adventitia externa" "rectal epithelium" "rectum epithelial tissue" "rectum epithelium" "epithelial tissue of rectum" + "tunica adventitia" + "tunica adventitia of vessel" + "adventitia externa" "regulation of protein catabolism" "regulation of cellular protein degradation" "regulation of cellular protein breakdown" @@ -23300,10 +23300,10 @@ "negative regulation of glycogen synthesis" "negative regulation of glycogen biosynthesis" "down regulation of glycogen biosynthetic process" + "solidity" "intraflagellar transport" "intraflagellar transport involved in microtubule-based flagellum organisation" "intraflagellar transport involved in cilium organization" - "solidity" "surface of body" "vascular network of iris" "iris vascular network" @@ -23405,6 +23405,7 @@ "carboxamides" "girdle - pectoral" "cingulum membri superioris" + "downregulation of vascular smooth muscle cell proliferation" "downregulation of VSMC proliferation" "down-regulation of vascular smooth muscle cell proliferation" "negative regulation of VSMC proliferation" @@ -23412,7 +23413,6 @@ "down regulation of VSMC proliferation" "down regulation of vascular smooth muscle cell proliferation" "down-regulation of VSMC proliferation" - "downregulation of vascular smooth muscle cell proliferation" "up regulation of AV node cell action potential" "up-regulation of AV node cardiac muscle cell action potential" "up regulation of AV node cardiac muscle cell action potential" @@ -23437,13 +23437,13 @@ "mesenchyme of kidney" "negative regulation of cellular amide metabolic process" "negative regulation of amide metabolism" + "duodenal lamina propria" + "lamina propria of duodenum" + "lamina propria mucosae of duodenum" "transferase activator" "up regulation of transferase activity" "upregulation of transferase activity" "up-regulation of transferase activity" - "duodenal lamina propria" - "lamina propria of duodenum" - "lamina propria mucosae of duodenum" "gastric body" "stomach body" "corpus gastricum (ventriculare)" @@ -23475,9 +23475,9 @@ "carbamate" "cloacal development" "mice and others" - "solid joint" "cellular structure morphogenesis" "cellular component morphogenesis" + "solid joint" "downregulation of programmed cell death by apoptosis of metanephric nephron tubule development" "downregulation of apoptotic process of metanephric nephron tubule development" "inhibition of apoptotic process of metanephric nephron tubule development" @@ -23523,10 +23523,6 @@ "regulation of defence response to bacterium" "regulation of defence response to bacteria" "regulation of defense response to bacteria" - "brainstem reticular formation" - "reticular formation (classical)" - "reticular formation of the brainstem" - "brain stem reticular formation" "negative regulation of hemopoietic stem cell proliferation" "downregulation of hematopoietic stem cell proliferation" "down regulation of hematopoietic stem cell proliferation" @@ -23534,6 +23530,10 @@ "down-regulation of hematopoietic stem cell proliferation" "downregulation of hemopoietic stem cell proliferation" "down regulation of hemopoietic stem cell proliferation" + "brainstem reticular formation" + "reticular formation (classical)" + "reticular formation of the brainstem" + "brain stem reticular formation" "innominate vein" "brachiocephalic venous tree" "up regulation of response to stimulus" @@ -23552,10 +23552,10 @@ "down-regulation of cardiac myofibril morphogenesis" "down-regulation of cardiac myofibril assembly" "downregulation of cardiac myofibril development" - "sperm ducts" - "sperm duct" "cranial neural nucleus" "nucleus of cranial nerve" + "sperm ducts" + "sperm duct" "serotonin breakdown" "serotonin catabolism" "serotonin degradation" @@ -23858,12 +23858,12 @@ "African ostrich" "tunica externa (adventitia)(arteriae)" "arterial adventitia" - "molecule" "protein localization in nuclear envelope" - "nuclear membrane organization involved in mitotic nuclear division" + "molecule" "skeleton of pelvic girdle" "skeletal parts of pelvic girdle" "pelvic girdle skeleton" + "nuclear membrane organization involved in mitotic nuclear division" "regulation of cardiac cell differentiation" "regulation of heart cell differentiation" "cloacal villi" @@ -24015,10 +24015,6 @@ "os clitoridis" "epithelial cell differentiation from mesenchymal cell" "mesenchymal-epithelial transition" - "retinachoroidal region" - "chorioretina" - "choroid and retina" - "retinachoroid" "mucosa of organ of cystic duct" "cystic duct mucous membrane" "cystic duct organ mucosa" @@ -24027,6 +24023,10 @@ "cystic ductal mucosa" "cystic duct mucosa" "organ mucosa of cystic duct" + "retinachoroidal region" + "chorioretina" + "choroid and retina" + "retinachoroid" "ovum development" "regulation of pigmentation during development" "red blood cell apoptotic process" @@ -24446,8 +24446,8 @@ "pelvis of left ureter" "windpipe mucosa" "mucous membrane of trachea" - "mucous membrane of windpipe" "tracheal mucous membrane" + "mucous membrane of windpipe" "mucosa of organ of trachea" "tunica mucosa tracheae" "mucosa of organ of windpipe" @@ -24489,6 +24489,10 @@ "positive regulation of amino acid formation" "positive regulation of cellular amino acid biosynthetic process" "positive regulation of amino acid biosynthesis" + "negative regulation of amine breakdown" + "negative regulation of amine degradation" + "negative regulation of amine catabolism" + "negative regulation of cellular amine catabolic process" "dilator muscle of pupil" "musculus dilatator pupillae" "dilator pupillae" @@ -24497,10 +24501,6 @@ "dilator of pupil" "dilator pupillae muscle" "pupillary dilator muscle" - "negative regulation of amine breakdown" - "negative regulation of amine degradation" - "negative regulation of amine catabolism" - "negative regulation of cellular amine catabolic process" "downregulation of embryonic eye development" "down regulation of embryonic eye development" "down regulation of embryonic camera-type eye development" @@ -24562,11 +24562,11 @@ "regulation of lipid catabolism" "regulation of lipid breakdown" "second meiotic division" + "subserosa of fallopian tube" + "subserosa of oviduct" "thoracic skeleton" "skeleton of thorax" "thoracic part of axial skeleton" - "subserosa of fallopian tube" - "subserosa of oviduct" "metabolite" "regulation of T lymphocyte polarization" "regulation of T-cell polarization" @@ -24594,10 +24594,10 @@ "up-regulation of protein localisation to presynapse" "up-regulation of recruitment of presynaptic proteins" "positive regulation of recruitment of presynaptic proteins" - "muscularis externa of cloaca" "down regulation of hepatocyte apoptotic process" "downregulation of hepatocyte apoptotic process" "down-regulation of hepatocyte apoptotic process" + "muscularis externa of cloaca" "T cell secretory granule organisation" "T-lymphocyte secretory granule organization" "T lymphocyte secretory granule organization" @@ -24699,9 +24699,15 @@ "epithelium of endometrium" "endometrium epithelial tissue" "epithelial tissue of endometrium" + "left atrium" + "left cardiac atrium" + "atrium sinistrum" + "cardiac left atrium" + "heart left atrium" + "left atrium of heart" + "glial cell generation" "pancreas parenchyma" "pancreatic parenchyma" - "glial cell generation" "positive regulation of cellular protein metabolic process" "up regulation of protein metabolic process" "up-regulation of protein metabolic process" @@ -24711,12 +24717,6 @@ "up-regulation of cellular protein metabolic process" "up regulation of cellular protein metabolic process" "positive regulation of cellular protein metabolism" - "left atrium" - "left cardiac atrium" - "atrium sinistrum" - "cardiac left atrium" - "heart left atrium" - "left atrium of heart" "pigment granule organisation" "capillary of lung" "regulation of establishment of protein localisation to chromosome" @@ -24760,8 +24760,8 @@ "regulation of serotonin formation" "regulation of serotonin biosynthesis" "glial cell programmed cell death by apoptosis" - "glia apoptosis" "programmed cell death of glia by apoptosis" + "glia apoptosis" "programmed cell death, glia" "apoptosis of glia" "apoptosis of glial cells" @@ -24898,8 +24898,8 @@ "dermal element" "vena splenica" "rodent" - "upregulation of immune effector process" "up regulation of immune effector process" + "upregulation of immune effector process" "up-regulation of immune effector process" "heart muscle development" "vertebrae" @@ -25019,8 +25019,8 @@ "down-regulation of synapse disassembly" "down regulation of synapse disassembly" "detoxification of nitrogenous compound" - "fibrous capsule of kidney" "renal capsule" + "fibrous capsule of kidney" "capsula fibrosa renis" "capsule of kidney" "occipital region of head" @@ -25231,13 +25231,13 @@ "land plants" "higher plants" "plants" + "hindgut lumen" "set of muscles" "set of skeletal muscles" "muscles set" "muscle group" "musculature" "musculi" - "hindgut lumen" "T-cell surface antigen T4/Leu-3 (human)" "hCD4" "glaucocystophytes" @@ -25280,8 +25280,8 @@ "cardiac vasculature morphogenesis" "heart blood vessel morphogenesis" "oxygen" - "insulin metabolism" "establishment of localisation in cell" + "insulin metabolism" "cell-cell signalling involved in lung development" "heart/pericardium" "CARBOXY GROUP" @@ -25331,9 +25331,9 @@ "basal plate midbrain" "basal plate midbrain region" "systemic arterial subtree" - "small bile duct cholangiocyte" "hematopoietic progenitor cell antigen CD34" "CD34" + "small bile duct cholangiocyte" "nerve tissue inflammatory response" "nervous tissue inflammatory response" "neural tissue inflammatory response" @@ -25391,10 +25391,10 @@ "fruit flies" "Drosophila" "fruit fly" - "embryological hepatic plate" - "primordium of the liver" "elastin fiber" "elastic fibre" + "embryological hepatic plate" + "primordium of the liver" "up regulation of transmembrane ion transport" "positive regulation of transmembrane ion transport" "positive regulation of ion membrane transport" @@ -25615,14 +25615,14 @@ "ossification involved in skeletal development" "endomembrane organization" "endomembrane system organisation" - "pelvis muscle" - "pelvis muscle organ" - "muscle organ of pelvis" - "pelvic muscle" "up-regulation of cell projection organization" "up regulation of cell projection organization" "upregulation of cell projection organization" "positive regulation of cell projection organisation" + "pelvis muscle" + "pelvis muscle organ" + "muscle organ of pelvis" + "pelvic muscle" "left lobe hepatic sinusoids" "digestive tract contents" "post-mitotic fusion of Golgi membranes" @@ -25892,9 +25892,9 @@ "pectoral cavity portion of connective tissue" "chest cavity connective tissue" "connective tissue of pectoral cavity" + "pectoral cavity connective tissue" "cavity of thorax textus connectivus" "chest cavity portion of connective tissue" - "pectoral cavity connective tissue" "portion of connective tissue of pectoral cavity" "textus connectivus of cavity of thorax" "textus connectivus of cavity of chest" @@ -25977,8 +25977,8 @@ "downregulation of lymphocyte mediated immunity" "down regulation of lymphocyte mediated immunity" "down-regulation of lymphocyte mediated immunity" - "microtubule-based flagellum organization" "midgut endoderm" + "microtubule-based flagellum organization" "cranium bone" "downregulation of neuroblast proliferation" "down regulation of neuroblast proliferation" @@ -26013,12 +26013,12 @@ "downregulation of synaptic transmission" "down-regulation of synaptic transmission" "down regulation of synaptic transmission" - "T-cell surface glycoprotein Lyt-2 (mouse)" - "CD8a (mouse)" - "mCD8A" "stomach D-cell" "stomach delta cell" "delta cell of stomach" + "T-cell surface glycoprotein Lyt-2 (mouse)" + "CD8a (mouse)" + "mCD8A" "programmed cell death by apoptosis involved in patterning of blood vessels" "apoptotic cell death involved in patterning of blood vessels" "apoptotic programmed cell death involved in patterning of blood vessels" @@ -26320,6 +26320,7 @@ "ciliated cell of the endometrium" "kidney interstitial cell differentiation" "lamina propria mucosa of small intestine" + "small bowel lamina propria mucosa" "small bowel lamina propria" "lamina propria of small bowel" "small intestine lamina propria" @@ -26330,28 +26331,27 @@ "lamina propria mucosae of small bowel" "lamina propria of mucosa of small intestine" "lamina propria mucosae of small intestine" - "small bowel lamina propria mucosa" "down-regulation of protein secretion" "downregulation of protein secretion" "down regulation of protein secretion" "sperm movement" "integumentary system" - "mitotic nuclear envelope breakdown" "chorionic villous stroma" + "mitotic nuclear envelope breakdown" + "glucose breakdown" + "glucose degradation" + "glucose catabolism" "reproductive organ of female organism" "reproductive structure of female organism" "sex organ of female organism" "female organism reproductive organ" "female organism sex organ" "female organism reproductive structure" - "female reproductive system organ" "female reproductive gland/organ" + "female reproductive system organ" "female organism reproductive system organ" "reproductive system organ of female organism" "female sex organ" - "glucose breakdown" - "glucose degradation" - "glucose catabolism" "upregulation of artery morphogenesis" "positive regulation of arteriogenesis" "up regulation of artery morphogenesis" @@ -26401,8 +26401,8 @@ "lamina limitans anterior corneae" "anterior limiting lamina" "Bowman's membrane" - "lamina limitans anterior (cornea)" "Bowman's anterior elastic lamina" + "lamina limitans anterior (cornea)" "anterior elastic lamina" "Bowman's layer" "respiratory system air" @@ -26571,15 +26571,15 @@ "embryogenesis" "embryonal development" "fibrous portion of pericardium" + "up-regulation of peptide secretion" + "upregulation of peptide secretion" + "up regulation of peptide secretion" "establishment of T lymphocyte polarity" "T lymphocyte polarization" "establishment of T-lymphocyte polarity" "T cell polarization" "T-cell polarization" "establishment of T-cell polarity" - "up-regulation of peptide secretion" - "upregulation of peptide secretion" - "up regulation of peptide secretion" "amino acid catabolism" "amino acid breakdown" "cellular amino acid catabolic process" @@ -26628,8 +26628,8 @@ "nerve cell" "yolk sac lumen" "cavity of yolk sac" - "response to monosaccharide stimulus" "vascular endothelial cell" + "response to monosaccharide stimulus" "endocardium of right atrium" "right atrial endocardium" "retinal layer formation" @@ -26709,12 +26709,12 @@ "phenol-containing compound synthesis" "phenol-containing compound anabolism" "integrin alpha with I domain" + "marginal zone of hindbrain" "epithelium morphogenesis" "up regulation of synaptic transmission" "upregulation of synaptic transmission" "up-regulation of synaptic transmission" "intracellular membrane-enclosed organelle" - "marginal zone of hindbrain" "T-lymphocyte differentiation antigen T8/Leu-2 (human)" "CD8a (human)" "hCD8A" @@ -26754,11 +26754,11 @@ "down-regulation of lipid transport" "cardiac ventricle muscle morphogenesis" "ventricular heart muscle morphogenesis" - "ovum" - "mature oocyte" "gonada mesenchyme" "mesenchyme of gonad" "mesenchyme of gonada" + "ovum" + "mature oocyte" "doudenal submucosa" "duodenal submucosa" "duodenum submucosa" @@ -26799,8 +26799,8 @@ "visceral serous pericardium proper morphogenesis" "heart epicardium morphogenesis" "visceral serous pericardium of heart morphogenesis" - "microtubule-based organelle localization" "pit eye" + "microtubule-based organelle localization" "epitheliocyte" "lobe of left lung" "lobe of the left lung" @@ -26862,10 +26862,10 @@ "cervical nerve tree" "cervical spinal nerve" "cavitas abdominis et pelvis" + "hepatobiliary system process" "Serotonin" "SEROTONIN" "3-(2-aminoethyl)-1H-indol-5-ol" - "hepatobiliary system process" "organa haemopoietica" "haemopoietic system" "haematological system" @@ -27005,12 +27005,12 @@ "male organism sex organ" "male sex organ" "reproductive organ of male organism" - "small molecule catabolism" - "ribonucleic acids" - "ribonucleic acid" "upregulation of chondrocyte development" "up regulation of chondrocyte development" "up-regulation of chondrocyte development" + "small molecule catabolism" + "ribonucleic acids" + "ribonucleic acid" "epicardial adipose tissue" "pericardial adipose tissue" "positive regulation of signalling process" @@ -27130,10 +27130,10 @@ "skin of body mucous gland" "skin mucus gland" "mucous gland of skin of body" + "organochalcogen compound" "acetate degradation" "acetate catabolism" "acetate breakdown" - "organochalcogen compound" "positive regulation of collagen formation" "positive regulation of collagen biosynthesis" "positive regulation of collagen synthesis" @@ -27296,8 +27296,8 @@ "up regulation of haemopoietic stem cell differentiation" "upregulation of hemopoietic stem cell differentiation" "up regulation of hematopoietic stem cell differentiation" - "positive regulation of hemopoietic stem cell differentiation" "up-regulation of hematopoietic stem cell differentiation" + "positive regulation of hemopoietic stem cell differentiation" "positive regulation of haemopoietic stem cell differentiation" "up-regulation of hemopoietic stem cell differentiation" "positive regulation of haematopoietic stem cell differentiation" @@ -27307,11 +27307,11 @@ "upregulation of haemopoietic stem cell differentiation" "upregulation of haematopoietic stem cell differentiation" "up-regulation of haematopoietic stem cell differentiation" - "trans-synaptic signalling via exosome" - "exosome mediated transynaptic signalling" "protein localization in nucleus" "protein localisation to nucleus" "protein localization in cell nucleus" + "trans-synaptic signalling via exosome" + "exosome mediated transynaptic signalling" "pancreatic islet" "pancreatic insula" "regulation of VSMC apoptotic process" @@ -27364,16 +27364,16 @@ "oocyte morphogenesis during differentiation" "vesical arteries" "arteria vesicali" + "programmed cell death by apoptosis of metanephric nephron tubule development" + "apoptotic process of metanephric nephron tubule development" + "apoptotic programmed cell death of metanephric nephron tubule development" + "apoptotic cell death of metanephric nephron tubule development" "cardiac elastic tissue" "heart elastic connective tissue" "textus connectivus elasticus of heart" "elastic tissue of heart" "heart textus connectivus elasticus" "elastic connective tissue of heart" - "programmed cell death by apoptosis of metanephric nephron tubule development" - "apoptotic process of metanephric nephron tubule development" - "apoptotic programmed cell death of metanephric nephron tubule development" - "apoptotic cell death of metanephric nephron tubule development" "carbamoyl" "female urethra mucosa" "mucous membrane of female urethra" @@ -27462,8 +27462,8 @@ "serous membrane of wall of intestine" "intestinal wall serous membrane" "wall of bowel serous membrane" - "serosa of wall of bowel" "bowel wall serosa" + "serosa of wall of bowel" "serosa of anatomical wall of bowel" "serosa of intestine wall" "serosa of bowel anatomical wall" @@ -27675,11 +27675,11 @@ "vein of kidney" "renal venous tree" "kidney vein" - "juveniles" - "juvenile organism" "up-regulation of defense response" "upregulation of defense response" "up regulation of defense response" + "juveniles" + "juvenile organism" "septa" "pharyngeal arch 4 mesenchyme from neural crest" "neural crest derived arch 4 mesenchyme" @@ -27722,8 +27722,6 @@ "up-regulation of epithelial cell of bile duct apoptotic process" "up regulation of cholangiocyte apoptotic process" "up-regulation of cholangiocyte apoptotic process" - "establishment of protein localization in extracellular region" - "establishment of protein localisation in extracellular region" "up-regulation of VSMC apoptotic process" "up regulation of vascular associated smooth muscle cell apoptotic process" "upregulation of vascular smooth muscle cell apoptotic process" @@ -27735,6 +27733,8 @@ "up regulation of vascular smooth muscle cell apoptotic process" "upregulation of vascular associated smooth muscle cell apoptotic process" "positive regulation of vascular smooth muscle cell apoptotic process" + "establishment of protein localization in extracellular region" + "establishment of protein localisation in extracellular region" "downregulation of skeletal muscle hypertrophy" "down-regulation of skeletal muscle hypertrophy" "down regulation of skeletal muscle hypertrophy" @@ -27802,8 +27802,8 @@ "epithelial tissue of vas deferens" "deferent duct epithelium" "epithelial tissue of vas deferen" - "vas deferen epithelium" "epithelium of vas deferen" + "vas deferen epithelium" "epithelium of sperm duct" "epithelium of deferent duct" "epithelial tissue of ductus deferens" @@ -27865,13 +27865,13 @@ "amine biosynthesis" "amine synthesis" "amine anabolism" - "ramus zygomaticotemporalis nervus zygomatici" - "ramus zygomaticotemporalis (Nervus zygomaticus)" - "zygomaticotemporal branch of zygomatic nerve" "mCDH5" "VE-cadherin (mouse)" "vascular endothelial cadherin (mouse)" "CD144 (mouse)" + "ramus zygomaticotemporalis nervus zygomatici" + "ramus zygomaticotemporalis (Nervus zygomaticus)" + "zygomaticotemporal branch of zygomatic nerve" "regulation of protein localization in ciliary membrane" "regulation of protein localisation in ciliary membrane" "regulation of protein localisation to ciliary membrane" @@ -27922,11 +27922,11 @@ "up-regulation of cardioblast differentiation" "upregulation of cardioblast differentiation" "up regulation of cardioblast differentiation" - "visceral peritoneum of rectum" "serous membrane of rectum" "rectum serous membrane" "rectal serosa" "rectum serosa" + "visceral peritoneum of rectum" "Donor" "lens epithelial tissue" "lens epithelium" @@ -27957,10 +27957,10 @@ "positive regulation of steroid metabolism" "up-regulation of steroid metabolic process" "upregulation of steroid metabolic process" + "alkaloid metabolism" "cavity of compartment of abdomen" "cavity of abdominal compartment" "space of abdominal compartment" - "alkaloid metabolism" "microtubule bundling" "uterus epithelial development" "acetate formation" @@ -28077,14 +28077,14 @@ "small intestine anatomical wall" "anatomical wall of small bowel" "small intestine wall" - "down regulation of muscle contraction" - "downregulation of muscle contraction" - "down-regulation of muscle contraction" "tela subserosa (hepar)" "subserosal tissue of liver" "hepatic subserosa" "subserous layer of liver" "tela subserosa hepatis" + "down regulation of muscle contraction" + "downregulation of muscle contraction" + "down-regulation of muscle contraction" "respiratory system skeletal muscle tissue" "skeletal muscle tissue of apparatus respiratorius" "skeletal muscle of respiratory system" @@ -28111,7 +28111,6 @@ "class A basic helix-loop-helix protein 17 (human)" "Stem cell protein (human)" "cortical interstitial tissue of left kidney" - "pulmonary venous tree organ part" "torso skeletal muscle tissue" "trunk skeletal muscle" "skeletal muscle tissue of torso" @@ -28119,6 +28118,7 @@ "skeletal muscle tissue of trunk" "torso skeletal muscle" "trunk skeletal muscle tissue" + "pulmonary venous tree organ part" "down regulation of execution phase of apoptosis" "down-regulation of execution phase of apoptosis" "downregulation of execution phase of apoptosis" @@ -28146,16 +28146,16 @@ "glucosamines catabolism" "glucosamines catabolic process" "glucosamine-containing compound breakdown" - "glucosamine-containing compound catabolism" "glucosamines breakdown" + "glucosamine-containing compound catabolism" "hilar cell of ovary" "dense core vesicle membrane" "outer layer of lateral plate mesoderm" - "epithelial-mesenchymal cell signalling involved in lung development" "negative regulation of liver cell differentiation" "downregulation of hepatocyte differentiation" "down regulation of hepatocyte differentiation" "down-regulation of hepatocyte differentiation" + "epithelial-mesenchymal cell signalling involved in lung development" "elastic tissue of apparatus respiratorius" "textus connectivus elasticus of respiratory system" "elastic tissue of respiratory system" @@ -28204,8 +28204,8 @@ "aromatic compound metabolism" "spinal arteries" "bone marrow stromal cell" - "smooth muscle fiber of sphincter of pupil" "parenchyma of right lobe of liver" + "smooth muscle fiber of sphincter of pupil" "regulation of secretory granule organisation" "up-regulation of cell growth" "upregulation of cell growth" @@ -28280,14 +28280,14 @@ "cortex of organ" "cortex" "sulfates" + "cardiac atrium muscle" + "atrial heart muscle" + "atrial cardiac muscle tissue" "epithelial-mesenchymal cell signalling" "apoptotic signalling pathway" "induction of apoptosis by extracellular signals" "amino-acid residue" "amino acid residue" - "cardiac atrium muscle" - "atrial heart muscle" - "atrial cardiac muscle tissue" "extracellular vesicular exosome assembly" "regulation of steroid metabolism" "down regulation of progression through cell cycle" @@ -28339,8 +28339,8 @@ "multicellular animals" "regulation of amide breakdown" "regulation of amide degradation" - "regulation of amide catabolism" "regulation of cellular amide catabolic process" + "regulation of amide catabolism" "regulation of amino acid membrane transport" "euphyllophytes" "pancreatic islet progenitor cell" @@ -28430,9 +28430,9 @@ "presumptive central nervous system" "future CNS" "bone of pectoral girdle" - "glans of female genital tubercle" "vesicle transport" "vesicular transport" + "glans of female genital tubercle" "true yeasts" "undifferentiated genital tubercle" "lungs pair" @@ -28471,12 +28471,12 @@ "hCD5" "body ganglion" "trunk ganglia" + "post-cranial axial skeletal system" + "cellular secretion" "protein localization in actin filament bundle" "protein localisation in actin filament bundle" "protein localisation to actin filament bundle" - "cellular secretion" "heterobicyclic compounds" - "post-cranial axial skeletal system" "apparatus respiratorius epithelium" "respiratory system epithelial tissue" "epithelium of respiratory system" @@ -28558,8 +28558,8 @@ "apparatus respiratorius arterial endothelium" "artery endothelium of apparatus respiratorius" "endothelium of artery of apparatus respiratorius" - "artery endothelium of respiratory system" "apparatus respiratorius endothelium of artery" + "artery endothelium of respiratory system" "apparatus respiratorius artery endothelium" "endothelium of artery of respiratory system" "arterial endothelium of respiratory system" @@ -28973,8 +28973,8 @@ "downregulation of colon smooth muscle contraction" "down regulation of colon smooth muscle contraction" "transitinal myocyte of sinuatrial node" - "biliary system epithelium" "optic cup morphogenesis involved in camera-style eye development" + "biliary system epithelium" "isthmus morphogenesis" "MHB morphogenesis" "regulation of heart chamber formation" @@ -29176,9 +29176,6 @@ "down regulation of biosynthetic process" "down-regulation of biosynthetic process" "negative regulation of synthesis" - "up regulation of phagocytosis" - "upregulation of phagocytosis" - "up-regulation of phagocytosis" "endothelium of vein of apparatus respiratorius" "vein endothelium of apparatus respiratorius" "venous endothelium of apparatus respiratorius" @@ -29190,6 +29187,9 @@ "vein endothelium of respiratory system" "apparatus respiratorius endothelium of vein" "respiratory system endothelium of vein" + "up regulation of phagocytosis" + "upregulation of phagocytosis" + "up-regulation of phagocytosis" "epithelial cell of gland of skin" "upregulation of translation initiation ternary complex assembly" "up regulation of formation of translation initiation ternary complex" @@ -29238,8 +29238,8 @@ "positive regulation of protein polymer catabolic process" "up regulation of protein polymer catabolism" "up-regulation of protein polymer catabolism" - "up-regulation of protein polymer breakdown" "activation of protein polymer breakdown" + "up-regulation of protein polymer breakdown" "upregulation of protein depolymerization" "upregulation of protein polymer degradation" "up-regulation of protein polymer catabolic process" @@ -29415,8 +29415,8 @@ "fly-resilin" "fruit fly protein" "antennomere 12"@en - "antennomere 4"@en "pteralia"@en + "antennomere 4"@en "fan-like" "antennomere 3" "cervical membrane" diff --git a/src/ontology/reports/xrefs.tsv b/src/ontology/reports/xrefs.tsv index cc2ad05..c3afd6b 100644 --- a/src/ontology/reports/xrefs.tsv +++ b/src/ontology/reports/xrefs.tsv @@ -148,8 +148,8 @@ "MA:0000577" "Wikipedia:Syncytiotrophoblast" "FMA:83040" - "SCTID:256965005" "NCIT:C33918" + "SCTID:256965005" "BTO:0001335" "EHDAA:129" "UMLS:C1135936" @@ -473,8 +473,8 @@ "NCIT:C13236" "HAO:0000004" "XAO:0004001" - "AEO:0000004" "TAO:0001487" + "AEO:0000004" "BILA:0000004" "FBbt:00007019" "ZFA:0001487" @@ -709,6 +709,9 @@ "SCTID:362210003" "NCIT:C33459" "EMAPA:28518" + "MA:0002826" + "EMAPA:35447" + "FMA:58517" "VHOG:0001730" "FMA:55671" "AAO:0010016" @@ -721,9 +724,6 @@ "EHDAA2:0003072" "CARO:0000072" "ZFA:0001490" - "MA:0002826" - "EMAPA:35447" - "FMA:58517" "MESH:D039901" "FMA:84790" "FMA:225275" @@ -810,8 +810,6 @@ "FMA:45654" "BTO:0003099" "MetaCyc:GLYCOCAT-PWY" - "MA:0001807" - "EMAPA:37574" "FMA:70300" "Wikipedia:Bulbus_cordis" "SCTID:361525002" @@ -821,6 +819,8 @@ "UMLS:C1284055" "EHDAA:768" "NCIT:C34114" + "MA:0001807" + "EMAPA:37574" "EV:0100088" "VHOG:0000294" "NCIT:C43612" @@ -1032,8 +1032,8 @@ "BTO:0000556" "FMA:69069" "UMLS:C0920502" - "XAO:0003011" "FBbt:00000110" + "XAO:0003011" "MESH:D005855" "EMAPA:36033" "AAO:0000480" @@ -1131,8 +1131,8 @@ "BILA:0000139" "MA:0003174" "EMAPA:35952" - "EHDAA2:0004044" "NCIT:C34321" + "EHDAA2:0004044" "FMA:321917" "Wikipedia:Gonadal_ridge" "EFO:0001414" @@ -1303,8 +1303,8 @@ "EMAPA:16073" "TAO:0001120" "XAO:0000042" - "AAO:0011074" "UMLS:C1518271" + "AAO:0011074" "FBbt:00001057" "MAT:0000176" "MIAA:0000176" @@ -1326,6 +1326,7 @@ "SCTID:362225003" "UMLS:C0458421" "BTO:0001462" + "OGES:000004" "FBdv:00005317" "BilaDO:0000008" "XAO:1000005" @@ -1336,7 +1337,6 @@ "OGES:000019" "MmusDv:0000013" "ZFS:0000047" - "OGES:000004" "Wikipedia:Skull_roof" "XAO:0003169" "ZFA:0000863" @@ -1353,6 +1353,7 @@ "MA:0003193" "EMAPA:35362" "EMAPA:17152" + "Wikipedia:Semen" "UMLS:C2756969" "EMAPA:31488" "MESH:D012661" @@ -1364,7 +1365,6 @@ "NCIT:C13713" "BTO:0001230" "FMA:62966" - "Wikipedia:Semen" "Wikipedia:Immune_system" "ZFA:0000569" "FMA:295640" @@ -1489,13 +1489,13 @@ "CALOHA:TS-1266" "FMA:83624" "BTO:0002064" + "UMLS:C0227824" "EMAPA:37792" "MA:0001729" "NCIT:C33298" "FMA:17744" "Wikipedia:Perimetrium" "SCTID:253705006" - "UMLS:C0227824" "EMAPA:17510" "UMLS:C0030288" "RETIRED_EHDAA2:0002177" @@ -1533,9 +1533,9 @@ "Wikipedia:Luteinization" "UniProtKB:P19437" "Wikipedia:Phagocytosis" - "EMAPA:28811" - "Gmelin:2121" "EMAPA:18963" + "Gmelin:2121" + "EMAPA:28811" "FMA:66809" "FMA:15708" "SCTID:362171000" @@ -1719,8 +1719,8 @@ "Wikipedia:Golgi_apparatus" "Wikipedia:Biliary_system" "SCTID:361354009" - "GAID:279" "NCIT:C12678" + "GAID:279" "FMA:79646" "MESH:D001659" "MA:0001273" @@ -1792,12 +1792,12 @@ "EMAPA:17338" "FMA:9559" "VHOG:0001233" - "NCIT:C13182" - "UMLS:C0225337" - "FMA:64800" "http://www.sciencemag.org/content/313/5795/1922/F1.large.jpg" "TADS:0000147" "SPD:0000130" + "NCIT:C13182" + "UMLS:C0225337" + "FMA:64800" "VHOG:0001216" "UMLS:C1179027" "AAO:0011110" @@ -1865,8 +1865,8 @@ "FMA:86188" "EMAPA:35932" "MA:0000066" - "EMAPA:37234" "SCTID:362666008" + "EMAPA:37234" "MA:0000028" "FMA:24217" "FMA:15696" @@ -2083,13 +2083,13 @@ "FMA:18336" "KUPO:0001115" "Wikipedia:Phosphorylation" + "EMAPA:16171" + "EHDAA2:0000736" + "EHDAA:364" "EHDAA2:0000031" "EHDAA:583" "EMAPA:16382" "VHOG:0000510" - "EMAPA:16171" - "EHDAA2:0000736" - "EHDAA:364" "Reactome:R-HSA-8875871" "Reactome:R-HSA-3560789" "Reactome:R-HSA-427555" @@ -2132,8 +2132,8 @@ "FMA:18930" "MA:0001940" "Wikipedia:Artery_to_the_ductus_deferens" - "EMAPA:37513" "SCTID:279659005" + "EMAPA:37513" "Wikipedia:Organelle" "NIF_Subcellular:sao1539965131" "Wikipedia:Wolffian_duct" @@ -2196,7 +2196,6 @@ "AEO:0000184" "EMAPA:37712" "MA:0000723" - "FMA:239607" "NCIT:C96299" "Wikipedia:Tendon_sheath" "FMA:45087" @@ -2204,6 +2203,7 @@ "BTO:0000051" "SCTID:361885006" "FMA:76715" + "FMA:239607" "EMAPA:37864" "FMA:71297" "GC_ID:1" @@ -2229,12 +2229,12 @@ "EHDAA2:0004587" "FMA:14598" "SCTID:259740004" - "GC_ID:1" "Wikipedia:Lateral_plate_mesoderm#Division_into_layers" "XAO:0000276" "BILA:0000044" "FMA:295568" "AAO:0011102" + "GC_ID:1" "FMA:69065" "GC_ID:1" "PMID:17572334" @@ -2274,8 +2274,8 @@ "MA:0001614" "FMA:63133" "AAO:0000612" - "EHDAA:5063" "SCTID:243931006" + "EHDAA:5063" "EMAPA:17396" "MA:0003155" "NCIT:C69315" @@ -2814,16 +2814,16 @@ "SCTID:361413002" "KEGG:C00017" "BTO:0000137" - "EFO:0003466" - "AAO:0000470" - "TAO:0001376" - "ZFA:0001376" - "XAO:0004132" "FMA:14272" "EMAPA:36293" "EV:0100028" "SCTID:40022005" "galen:IntimaOfArtery" + "EFO:0003466" + "AAO:0000470" + "TAO:0001376" + "ZFA:0001376" + "XAO:0004132" "EHDAA2:0002094" "MA:0002940" "EMAPA:18247" @@ -2839,6 +2839,7 @@ "FBbt:00007242" "EMAPA:37393" "MA:0001530" + "ZFA:0001273" "MA:0001906" "XAO:0003084" "FMA:54398" @@ -2849,7 +2850,6 @@ "EHDAA:8005" "EHDAA2:0004606" "VHOG:0000428" - "ZFA:0001273" "FBbt:00100152" "FMA:68647" "GC_ID:1" @@ -3040,8 +3040,8 @@ "CALOHA:TS-0116" "EFO:0010709" "NCIT:C49274" - "CALOHA:TS-1262" "FMA:15627" + "CALOHA:TS-1262" "EMAPA:27782" "TAO:0001287" "UMLS:C0022674" @@ -3140,6 +3140,7 @@ "CALOHA:TS-1275" "KUPO:0001099" "FMA:62104" + "EHDAA:350" "EHDAA2:0001968" "EHDAA:7860" "EHDAA:4790" @@ -3152,7 +3153,6 @@ "EHDAA:4784" "UMLS:C1515087" "EMAPA:16096" - "EHDAA:350" "MA:0001815" "EMAPA:37570" "Wikipedia:Atrioventricular_node" @@ -3365,7 +3365,6 @@ "galen:HepaticArtery" "UMLS:C0019145" "Wikipedia:Urination" - "ZFA:0000014" "Wikipedia:Dorsal_aorta" "EHDAA:402" "XAO:0000051" @@ -3375,6 +3374,7 @@ "BTO:0004673" "SCTID:338637006" "AAO:0011029" + "ZFA:0000014" "galen:StriatedMuscle" "UMLS:C1331262" "EHDAA2:0003140" @@ -3462,8 +3462,8 @@ "BSA:0000089" "GAID:173" "MAT:0000453" - "FMA:24028" "GC_ID:1" + "FMA:24028" "BIRNLEX:2665" "FMA:62420" "SCTID:278748001" @@ -3734,8 +3734,8 @@ "Reactome:R-HSA-5246514" "Reactome:R-HSA-5205661" "Reactome:R-HSA-5250884" - "Reactome:R-HSA-5250972" "Reactome:R-HSA-5210943" + "Reactome:R-HSA-5250972" "Reactome:R-HSA-5210947" "Reactome:R-HSA-5229111" "Reactome:R-HSA-3149434" @@ -3960,8 +3960,8 @@ "BIRNLEX:2548" "MA:0001161" "BTO:0001123" - "UMLS:C1516496" "FMA:76621" + "UMLS:C1516496" "NCIT:C34121" "AAO:0010153" "XAO:0003059" @@ -3977,8 +3977,8 @@ "EMAPA:37283" "UMLS:C0598782" "NCIT:C61460" - "XAO:0000218" "MESH:D005121" + "XAO:0000218" "Wikipedia:Appendage" "EV:0100155" "HAO:0000144" @@ -4180,13 +4180,13 @@ "EMAPA:37598" "Wikipedia:Sulfur_metabolism" "SCTID:205214009" + "EHDAA2:0001371" "MESH:D036703" "OGEM:000006" "BILA:0000059" "GAID:1294" "Wikipedia:Blastula" "BTO:0000128" - "EHDAA2:0001371" "VHOG:0000652" "EHDAA:2181" "EHDAA2:0001327" @@ -4253,13 +4253,13 @@ "EMAPA:37261" "MA:0000508" "SCTID:305071003" - "EHDAA2:0001945" "EMAPA:37784" "MA:0001688" "FMA:19683" "SCTID:279477005" "KEGG:C06073" "Wikipedia:Indole_alkaloid" + "EHDAA2:0001945" "BTO:0002010" "MESH:D063194" "Wikipedia:Adventitia" @@ -4618,12 +4618,12 @@ "MA:0001539" "NCIT:C49243" "EMAPA:35443" - "EHDAA:8979" - "EHDAA2_RETIRED:0003148" - "AEO:0000148" "MA:0001809" "EMAPA:37584" "MA:0001810" + "EHDAA:8979" + "EHDAA2_RETIRED:0003148" + "AEO:0000148" "FMA:62939" "FMA:40877" "EFO:0010711" @@ -4666,6 +4666,7 @@ "GC_ID:1" "PMID:23020233" "EMAPA:37415" + "FMA:17553" "EMAPA:17799" "EHDAA2:0002087" "SCTID:280211001" @@ -4677,7 +4678,6 @@ "MESH:D008442" "BTO:0001378" "MA:0001103" - "FMA:17553" "Wikipedia:Spermiogenesis" "FMA:83810" "BTO:0002691" @@ -4698,6 +4698,7 @@ "FMA:9492" "GAID:560" "Wikipedia:Purkinje_fiber" + "UniProtKB:P16871" "UMLS:C0020888" "NCIT:C12734" "EMAPA:37151" @@ -4705,7 +4706,6 @@ "EHDAA2:0000811" "MESH:D007084" "MA:0002142" - "UniProtKB:P16871" "VSAO:0000139" "XAO:0004017" "ZFA:0005620" @@ -4716,6 +4716,10 @@ "EMAPA:31482" "FBbt:00004934" "CALOHA:TS-2193" + "SCTID:86915006" + "UMLS:C0225358" + "Wikipedia:Muscular_layer" + "BTO:0004838" "EMAPA:19032" "Wikipedia:Visceral_pericardium" "EMAPA:16589" @@ -4723,10 +4727,6 @@ "FMA:84882" "SCTID:243955001" "MA:0000484" - "SCTID:86915006" - "UMLS:C0225358" - "Wikipedia:Muscular_layer" - "BTO:0004838" "Wikipedia:Food_additive" "GC_ID:1" "EMAPA:37475" @@ -4871,8 +4871,8 @@ "TAO:0000998" "FMA:293859" "XAO:0000053" - "EFO:0003603" "ZFA:0000998" + "EFO:0003603" "EHDAA:655" "EMAPA:16099" "GC_ID:1" @@ -4899,15 +4899,14 @@ "FMA:81494" "MA:0000513" "EMAPA:37252" - "KEGG:C00420" "MA:0003220" "EMAPA:32904" + "KEGG:C00420" "Reactome:R-HSA-9662818" "Reactome:R-HSA-9662747" "FMA:82485" - "FMA:69075" - "ZFA:0000254" "FMA:79792" + "ZFA:0000254" "EHDAA2:0001382" "EFO:0003434" "EHDAA:2163" @@ -4915,6 +4914,7 @@ "TAO:0000254" "EMAPA:17066" "XAO:0001101" + "FMA:69075" "galen:PneumaticBone" "SCTID:333008005" "FMA:7478" @@ -5319,10 +5319,10 @@ "EMAPA:35501" "Wikipedia:Hearing_(sense)" "Wikipedia:Sclera#Histology" - "MA:0002405" "EMAPA:29046" "SCTID:259488000" "FMA:18318" + "MA:0002405" "EHDAA2:0002212" "Wikipedia:Yolk_sac" "NCIT:C14128" @@ -5700,8 +5700,8 @@ "FMA:24728" "NIF_Subcellular:sao1337158144" "Wikipedia:Karyogamy" - "MA:0002962" "EMAPA:18766" + "MA:0002962" "GC_ID:1" "EV:0100071" "Wikipedia:Intestine" @@ -5749,8 +5749,8 @@ "ZFA:0000041" "EFO:0001981" "EHDAA2:0001128" - "VHOG:0000152" "XAO:0000050" + "VHOG:0000152" "MIAA:0000174" "EHDAA:160" "CALOHA:TS-0623" @@ -5823,15 +5823,6 @@ "EHDAA2:0001962" "UMLS:C0042459" "galen:SuperiorVenaCava" - "OGES:000027" - "XAO:1000093" - "BILS:0000113" - "ZFS:0000044" - "OGES:000026" - "EV:0300064" - "MmusDv:0000110" - "EV:0300070" - "MIAA:0000403" "EV:0100072" "EFO:0000841" "VHOG:0000055" @@ -5853,6 +5844,15 @@ "CALOHA:TS-0942" "FMA:7200" "XAO:0000130" + "OGES:000027" + "XAO:1000093" + "BILS:0000113" + "ZFS:0000044" + "OGES:000026" + "EV:0300064" + "MmusDv:0000110" + "EV:0300070" + "MIAA:0000403" "FMA:84646" "UniProtKB:P06729" "GC_ID:1" @@ -6257,8 +6257,8 @@ "GC_ID:1" "PIRSF:PIRSF002021" "UMLS:C0004600" - "galen:Back" "GAID:30" + "galen:Back" "NCIT:C13062" "MESH:D001415" "EFO:0001405" @@ -6363,8 +6363,8 @@ "Wikipedia:Ketone" "GC_ID:1" "EHDAA2:0004070" - "EFO:0010706" "Wikipedia:Heart_development" + "EFO:0010706" "Wikipedia:Chromosome" "FMA:75383" "SCTID:245445008" @@ -6586,7 +6586,6 @@ "FBbt:00005426" "EFO:0001649" "Wikipedia:Anlage_(biology)" - "Wikipedia:Tendon" "EHDAA2:0003091" "GAID:276" "UMLS:C0039508" @@ -6605,6 +6604,7 @@ "galen:Tendon" "VHOG:0001286" "VSAO:0000073" + "Wikipedia:Tendon" "Wikipedia:Extracellular" "FMA:84639" "BTO:0002441" @@ -7030,14 +7030,14 @@ "EMAPA:32918" "FMA:5898" "SCTID:91833003" - "MA:0002514" - "UMLS:C0227179" - "NCIT:C52555" - "FMA:79662" "TAO:0001460" "EFO:0003689" "BTO:0006051" "ZFA:0001460" + "MA:0002514" + "UMLS:C0227179" + "NCIT:C52555" + "FMA:79662" "BTO:0004733" "IDOMAL:0000443" "Wikipedia:Endocytosis" @@ -7046,8 +7046,8 @@ "EMAPA:36573" "UMLS:C1512086" "NCIT:C25787" - "BTO:0005000" "GC_ID:1" + "BTO:0005000" "FBbt:00001730" "TAO:0001309" "Wikipedia:Neurogenic_placodes" @@ -7224,9 +7224,9 @@ "TAO:0001238" "EMAPA:16841" "SCTID:245398005" - "UMLS:C0010672" "MA:0000355" "EHDAA2:0000333" + "UMLS:C0010672" "TAO:0005166" "NCIT:C32421" "EHDAA:3045" @@ -7370,18 +7370,18 @@ "BTO:0000123" "EMAPA:35965" "MA:0002867" - "EMAPA:36299" - "NCIT:C33818" - "UMLS:C0225342" - "SCTID:61066005" - "Wikipedia:Tunica_externa_(vessels)" - "BTO:0002010" "FMA:17510" "VHOG:0001037" "MA:0003219" "EHDAA2:0001594" "EMAPA:17898" "CALOHA:TS-2066" + "EMAPA:36299" + "UMLS:C0225342" + "NCIT:C33818" + "SCTID:61066005" + "Wikipedia:Tunica_externa_(vessels)" + "BTO:0002010" "SCTID:280508003" "SCTID:181380003" "XAO:0004162" @@ -7444,8 +7444,8 @@ "WBls:0000003" "SCTID:296280003" "FBdv:00005289" - "EV:0300001" "FMA:72652" + "EV:0300001" "BilaDO:0000002" "XAO:1000012" "MmusDv:0000002" @@ -7505,6 +7505,10 @@ "VSAO:0000092" "AEO:0000147" "EMAPA:32731" + "VHOG:0001240" + "EMAPA:16368" + "EHDAA2:0001242" + "EHDAA:1015" "TAO:0000407" "VSAO:0000156" "EHDAA2:0001420" @@ -7520,10 +7524,6 @@ "ZFA:0000407" "Wikipedia:Pectoral_girdle" "NCIT:C33547" - "VHOG:0001240" - "EMAPA:16368" - "EHDAA2:0001242" - "EHDAA:1015" "FMA:18303" "AAO:0000986" "Wikipedia:Cyclic_compound" @@ -7960,14 +7960,14 @@ "NCIT:C13270" "MA:0002516" "UMLS:C0030296" - "TAO:0001268" - "FMA:55678" - "ZFA:0001268" "FMA:54501" "SCTID:280160003" "NLX:28532" "EMAPA:37066" "Wikipedia:Cranial_nerve_nucleus" + "TAO:0001268" + "FMA:55678" + "ZFA:0001268" "BILA:0000066" "FMA:9639" "EMAPA:32738" @@ -7996,11 +7996,11 @@ "WBbt:0005113" "FBbt:00005125" "FMA:72025" - "EMAPA:35323" "MA:0001573" + "EMAPA:35323" "UMLS:C0014259" - "SCTID:368827009" "NCIT:C12707" + "SCTID:368827009" "ZFA:0001687" "FMA:63882" "MA:0001242" @@ -8470,8 +8470,8 @@ "Wikipedia:Amidase" "MA:0000387" "EMAPA:30823" - "SCTID:110701000" "FMA:14690" + "SCTID:110701000" "Wikipedia:Oogenesis" "FMA:256161" "Wikipedia:Neurotoxin" @@ -8687,8 +8687,8 @@ "UMLS:C0025473" "RETIRED_EHDAA2:0001125" "MA:0002177" - "EMAPA:17348" "MESH:D008642" + "EMAPA:17348" "Wikipedia:Mesenteric_vein" "SCTID:304045008" "EMAPA:18306" @@ -8910,8 +8910,8 @@ "EHDAA:5919" "UMLS:C0231057" "Wikipedia:Definitive_urogenital_sinus" - "NCIT:C34322" "EMAPA:17379" + "NCIT:C34322" "VHOG:0000626" "EMAPA:16086" "EHDAA2:0002215" @@ -8957,17 +8957,6 @@ "MA:0002731" "SCTID:253526009" "EMAPA:35307" - "EMAPA:32925" - "SCTID:371401008" - "FMA:63120" - "MA:0000724" - "VHOG:0001430" - "Reactome:R-HSA-194130" - "Reactome:R-HSA-194083" - "Reactome:R-HSA-5661198" - "Reactome:R-HSA-5661184" - "Reactome:R-HSA-9733964" - "Reactome:R-HSA-194079" "NCIT:C12869" "FMA:7097" "galen:LeftAtrium" @@ -8981,6 +8970,17 @@ "VHOG:0000369" "EMAPA:17315" "BTO:0001702" + "Reactome:R-HSA-194130" + "Reactome:R-HSA-194083" + "Reactome:R-HSA-5661198" + "Reactome:R-HSA-5661184" + "Reactome:R-HSA-9733964" + "Reactome:R-HSA-194079" + "EMAPA:32925" + "SCTID:371401008" + "FMA:63120" + "MA:0000724" + "VHOG:0001430" "FMA:14121" "NCIT:C13053" "MA:0000717" @@ -9005,13 +9005,13 @@ "EMAPA:16133" "FMA:18149" "BTO:0003157" + "FBbt:00004873" "EMAPA:35747" "VHOG:0001210" "TAO:0007063" "ZFA:0007063" "EHDAA:362" "EHDAA2:0001628" - "FBbt:00004873" "KUPO:0001015" "SCTID:272631008" "MA:0000522" @@ -9121,8 +9121,8 @@ "FMA:58102" "SCTID:361318005" "Wikipedia:Fibrous_tunic_of_eyeball" - "VHOG:0001750" "Wikipedia:Upper_lip" + "VHOG:0001750" "ZFA:0005226" "TAO:0001970" "MA:0000919" @@ -9138,8 +9138,8 @@ "NCIT:C34210" "SCTID:361410004" "TGMA:0001036" - "Wikipedia:Midgut" "EHDAA:983" + "Wikipedia:Midgut" "XAO:0000103" "MA:0001564" "BILA:0000086" @@ -9277,8 +9277,8 @@ "TAO:0001410" "BTO:0004687" "ZFA:0001410" - "galen:Orbit" "FMA:53074" + "galen:Orbit" "Wikipedia:Orbit_(anatomy)" "MESH:D009915" "NCIT:C12347" @@ -9291,13 +9291,13 @@ "SCTID:361529008" "VHOG:0000540" "Wikipedia:Metanephric_blastema" - "EHDAA:4041" "EHDAA2:0004062" + "EHDAA:4041" "EMAPA:17375" "SCTID:276456008" "FMA:7095" - "Wikipedia:Perception" "FMA:70567" + "Wikipedia:Perception" "SCTID:299803005" "FMA:19238" "EMAPA:29767" @@ -9556,6 +9556,8 @@ "MA:0002739" "FMA:9582" "GC_ID:1" + "FMA:54367" + "EMAPA:18396" "MA:0000165" "NCIT:C13056" "EFO:0001949" @@ -9570,8 +9572,6 @@ "WBbt:0005737" "Wikipedia:Muscular_system" "UMLS:C0026845" - "FMA:54367" - "EMAPA:18396" "ZFA:0001665" "SCTID:279285003" "TAO:0002209" @@ -9686,6 +9686,7 @@ "FMA:268736" "GC_ID:1" "Wikipedia:Intracellular" + "UMLS:C1518263" "EMAPA:17171" "EHDAA:4763" "EHDAA2:0001253" @@ -9700,21 +9701,20 @@ "EMAPA:18590" "BTO:0000929" "ZFA:0000046" - "UMLS:C1518263" "VHOG:0001006" "EMAPA:16881" "EHDAA:696" "EMAPA:16163" - "MA:0002825" - "BTO:0005768" - "FMA:19153" - "CALOHA:TS-2063" - "EMAPA:30445" "MESH:D010189" "BTO:0000504" "GAID:1166" "FMA:62973" "CALOHA:TS-2235" + "MA:0002825" + "BTO:0005768" + "FMA:19153" + "CALOHA:TS-2063" + "EMAPA:30445" "SCTID:245777007" "TAO:0002060" "EHDAA2:0001020" @@ -10238,6 +10238,7 @@ "AAO:0010383" "FMA:70557" "BTO:0004301" + "ZFA:0001073" "SCTID:261623000" "VHOG:0000358" "EMAPA:17024" @@ -10248,7 +10249,6 @@ "FMA:72298" "CALOHA:TS-0922" "VHOG:0001348" - "ZFA:0001073" "Wikipedia:Enzyme" "EV:0200009" "ncithesaurus:Beta_Cell" @@ -10340,7 +10340,6 @@ "CARO:0001000" "FMA:83115" "FBbt:00007060" - "FMA:83673" "EMAPA:18043" "SCTID:361725000" "UMLS:C0222645" @@ -10351,6 +10350,7 @@ "XAO:0004011" "VSAO:0000056" "MA:0000308" + "FMA:83673" "Wikipedia:Amino_acid_synthesis" "SCTID:61647009" "MA:0003200" @@ -10448,8 +10448,8 @@ "MA:0002531" "BTO:0004577" "GC_ID:1" - "UniProtKB:P01731" "FMA:83410" + "UniProtKB:P01731" "Wikipedia:Cytoskeleton" "Wikipedia:Cognition" "EFO:0003656" @@ -10938,13 +10938,13 @@ "EHDAA:8124" "UMLS:C0029939" "GC_ID:1" + "TAO:0000207" + "ZFA:0000207" "SCTID:245251000" "NCIT:C49273" "EMAPA:37490" "UMLS:C1709901" "MA:0001680" - "TAO:0000207" - "ZFA:0000207" "FMA:23878" "VSAO:0000181" "EMAPA:35150" @@ -11212,8 +11212,8 @@ "Beilstein:2937999" "Reaxys:2937999" "LINCS:LSM-37072" - "Wikipedia:Embryonic_ventricle" "SCTID:361524003" + "Wikipedia:Embryonic_ventricle" "NCIT:C34160" "EMAPA:16350" "ZFA:0001719" @@ -11243,16 +11243,16 @@ "ZFA:0000434" "NCIT:C12788" "FBbt:00005157" + "EMAPA:17385" + "EMAPA:16858" + "EHDAA:5012" + "VHOG:0001090" "BTO:0003801" "FBbt:00057012" "CALOHA:TS-2191" "FMA:67343" "BTO:0000369" "MESH:D010063" - "EMAPA:17385" - "EMAPA:16858" - "EHDAA:5012" - "VHOG:0001090" "EMAPA:27027" "EMAPA:27097" "MA:0003213" @@ -11372,8 +11372,8 @@ "ZFA:0001675" "NCIT:C41168" "FMA:79770" - "MA:0003081" "SCTID:180960003" + "MA:0003081" "MESH:D066193" "FMA:71166" "neuronames:1654" @@ -11539,8 +11539,8 @@ "Wikipedia:Pylorus" "galen:Pylorus" "EHDAA2:0001580" - "FMA:14581" "GAID:333" + "FMA:14581" "EFO:0003421" "ZFA:0000053" "TAO:0000053" @@ -11696,8 +11696,8 @@ "UMLS:C0231056" "EMAPA:16832" "SCTID:308826008" - "EHDAA:214" "FMA:295525" + "EHDAA:214" "FMA:63368" "CALOHA:TS-2086" "AAO:0011090" @@ -11796,8 +11796,8 @@ "Wikipedia:Thorax" "EMAPA:35148" "VHOG:0001215" - "NCIT:C49194" "BTO:0004757" + "NCIT:C49194" "AAO:0011013" "UMLS:C1179025" "XAO:0000357" @@ -12504,10 +12504,10 @@ "FMA:75621" "DHBA:10649" "FMA:83913" + "UniProtKB:P55284" "FMA:52972" "Wikipedia:Zygomaticotemporal_nerve" "SCTID:280243001" - "UniProtKB:P55284" "galen:SpinalColumn" "NCIT:C33588" "EHDA:10119" @@ -12571,6 +12571,7 @@ "UMLS:C1708179" "GC_ID:1" "EHDAA2:0001193" + "FMA:67968" "NCIT:C12664" "MESH:D034841" "GAID:17" @@ -12582,14 +12583,12 @@ "MA:0003057" "galen:AbdominalCavity" "EMAPA:36505" - "FMA:67968" "Wikipedia:Lamina_of_the_vertebral_arch" "MESH:D008214" "VHOG:0001535" "CALOHA:TS-0583" "FMA:62863" "BTO:0000775" - "TAO:0000113" "FMA:76622" "EHDAA2:0000732" "EMAPA_RETIRED:16269" @@ -12598,6 +12597,7 @@ "EMAPA:16098" "EFO:0003492" "VHOG:0000332" + "TAO:0000113" "Reactome:R-HSA-9794270" "Reactome:R-HSA-2161500" "Reactome:R-HSA-9794523" @@ -12712,6 +12712,7 @@ "BILA:0000019" "EHDAA2:0003019" "AAO:0010017" + "SCTID:244848007" "SCTID:430160002" "GAID:543" "EHDAA2:0001579" @@ -12729,7 +12730,6 @@ "Wikipedia:Pulmonary_vein" "AAO:0010521" "XAO:0000394" - "SCTID:244848007" "NCIT:C13048" "MA:0000375" "CALOHA:TS-1312" @@ -12838,11 +12838,11 @@ "TAO:0000682" "EHDAA:4355" "EHDAA2:0004585" - "FMA:70611" "EHDAA2:0001010" "VHOG:0000840" "EMAPA:18317" "FMA:71657" + "FMA:70611" "EFO:0000966" "ZFA:0001115" "MA:0000004" @@ -12857,8 +12857,8 @@ "MIAA:0000296" "Wikipedia:Torso" "XAO:0003025" - "FMA:7181" "EMAPA:31857" + "FMA:7181" "TAO:0001115" "MAT:0000296" "UMLS:C0460005" @@ -12921,8 +12921,8 @@ "Wikipedia:Cortex_(anatomy)" "EFO:0000383" "EHDAA:9344" - "Wikipedia:Nuclear_envelope" "FMA:7283" + "Wikipedia:Nuclear_envelope" "GC_ID:1" "MA:0001582" "EV:0100129" @@ -13108,9 +13108,9 @@ "MIAA:0000344" "EFO:0000901" "TAO:0001573" + "FMA:302077" "Wikipedia:Secretion" "FMA:63071" - "FMA:302077" "VHOG:0000981" "EMAPA:32826" "CALOHA:TS-0023" @@ -13589,8 +13589,8 @@ "EHDAA2:0001384" "WBbt:0005178" "Wikipedia:Ovotestis" - "BTO:0000981" "MIAA:0000165" + "BTO:0000981" "EFO:0000971" "MAT:0000165" "TAO:0000094" @@ -13906,8 +13906,8 @@ "MESH:D002970" "BILS:0000107" "XAO:1000004" - "PdumDv:0000200" "OGES:000015" + "PdumDv:0000200" "MmusDv:0000004" "EFO:0001290" "FBdv:00000054" @@ -13967,9 +13967,9 @@ "VHOG:0001234" "EMAPA:17339" "FMA:83453" + "MA:0001830" "BTO:0001660" "EMAPA:35734" - "MA:0001830" "SCTID:244231007" "FMA:3789" "EMAPA:17856" @@ -14001,6 +14001,7 @@ "UMLS:C0227987" "UMLS:C0036614" "NCIT:C52552" + "EHDAA2:0000640" "BILA:0000071" "ZFA:0001493" "AEO:0000071" @@ -14011,7 +14012,6 @@ "XAO:0004004" "TAO:0001493" "AAO:0010057" - "EHDAA2:0000640" "EMAPA:37246" "MA:0000584" "Wikipedia:Protein_catabolism"