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AminoAcid to Genome Coordinates #151

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chhorstmann opened this issue Mar 13, 2024 · 1 comment
Open

AminoAcid to Genome Coordinates #151

chhorstmann opened this issue Mar 13, 2024 · 1 comment

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@chhorstmann
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I would like to retrieve the genomic coordinates of specific amino acids in a list of proteins using the proteintoGenome or transcripttoGenome function.
Using information from UniProt I could get the position of the amino acid in the protein sequence. I used the canonical Ensembl Peptide ID and the proteinToGenome function to map this to the genome. Unfortunately, I am also selecting other amino acids than the desired ones. Maybe someone had a similar experience or wanted to do something similar and could help me with this problem.

@jorainer
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what do you mean with "selecting other amino acids than the desired ones"? you can specifically select the amino acid (range) in the protein and then map this to genomic coordinates. Since all mapping performed in/by ensembldb based on position information provided by Ensembl I would suggest you choose the specific Ensembl protein you're interested and choose the amino acid sequence within that protein.

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