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ukbtools 0.11.3.9000

Bug fix:

dplyr update broke ukb_icd_diagnosis. Fixed in dev version.

ukbtools 0.11.3

Corrected functionality:

Updated earlier typo/change that made ukb_df incorrectly convert all column types to character (caused by replacing stringr::str_interp to stringr::str_c when passing internal column type vector to data.table::fread, without updating argument)

Bug fix:

Cleared bug in ukb_icd_freq_by for disease frequency against a quantitative trait.

Made ukb_df column name from description regex find/replace more general to capture all variations of "uses data coding"

Updated functionality:

ukb_icd_keyword internal regex search ignore.case defaults to TRUE, with and option to set added to arguments.

ukbtools 0.11.1

Test data:

Added example UKB data ukbXXXX.tab, ukbXXXX.r, ukbXXXX.html to test the 'read' and 'summarise' functionality ukb_df, ukb_df_field, and ukb_context. See the section "An example fileset" in the vignette for details.

Updated functionality:

ukb_icd_freq_by with freq.plot = TRUE plots a barplot for categorical reference variables, and plots diagnosis frequencies at the midpoint of each group for quantitative reference variables.

Webpage:

The ukbtools webpage has been rebuilt with pkgdown and includes the vignette under the Articles tab.

ukbtools 0.11.0

Updated functionality:

  • ukb_df: Replaced readr::read_tsv with data.table::fread for faster read. Also includes an n_threads argument passed to data.table::fread, which may make read faster. Column names now include field code to ensure names are unique (UK Biobank sometimes use the same description for more than one variable)

Defunct functionality:

  • Added defunct message to ukb_gen_meta, ukb_gen_pcs, ukb_gen_excl, ukb_gen_rel, ukb_gen_het, ukb_gen_excl_to_na, and ukb_gen_write_plink_excl. ukb_defunct explains why these have become defunct and where to get UK Biobank genetic (meta)data.

New functionality:

  • Since the UKB changed the way they serve up genetic metadata, the following work with files described in UKB Resource 531: ukb_gen_sqc_names supplies column names for the separately downloaded sample QC file; ukb_gen_rel_count does the same as before (a count of levels of relatedness or a plot) but with separately downloaded relatedness data; ukb_gen_related_with_data returns subset of relatedness data in which both IDs have data on a phenotype of interest; ukb_gen_samples_to_remove returns a list of individuals to exclude in order to remove relatedness (one possible solution to a maximal subset problem).

ukbtools 0.10.1

Bug fix:

  • ukb_icd_freq_by: corrected order by levels of reference.var in the optional plot. (order in the default dataframe returned was correct.)

  • ukb_df: corrected tab file path update in r source file. Specifically, made regular expression more specific (1 case reported of regular expression matching word elsewhere in the source file.). Also, replaced utils::read.delim with readr::read_tsv for faster read, with progress bar.

ukbtools 0.10.0

New functionality:

  • ukb_icd_freq_by returns frequency for one or more ICD diagnoses by levels of a reference variable and includes an optional plot

  • ukb_df_full_join (a thin wrapper around dplyr::full_join) recursively called on a list of UKB datasets

  • ukb_df_duplicated_names to identify duplicated names within a dataset. The variable prefix (constructed from its description), index, and array should make the column name unique. However, typos in UKB documentation that give two variables the do not increment index/array have been observed. You will want to identify these and update them appropriately. We expect the occurrence of such duplicates will be rare.

Updated functionality:

  • ukb_icd_diagnosis now takes one or more individual ids and returns a dataframe with a potential message noting ids with no diagnoses

  • ukb_icd_keyword accepts a character vector of one or more "keywords" and returns all ICD descriptions including any of the keywords

ukbtools 0.9.0

  • beta release to CRAN. Feature complete but may contain unknown bugs.