| layout | id | title | type | fail_mode | status | contact | implementations | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
rule |
GORULE:0000046 |
The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms. |
report |
soft |
implemented |
|
Annotations representing self-binding mean that the gene product annotated interacts with itself. Therefore, the entity in the 'with/from' column (colomn 8) should be the same as the gene product (column 2).
Self-binding terms include GO:0042803 protein homodimerization activity, GO:0051260 protein homooligomerization, GO:0051289 protein homotetramerization, GO:0070207 protein homotrimerization, GO:0043621 protein self-association, and GO:0032840 intramolecular proline-rich ligand binding (and their 'is_a' descendants).