diff --git a/integration-tests/hibernate-orm-panache/src/main/java/io/quarkus/it/panache/defaultpu/TestEndpoint.java b/integration-tests/hibernate-orm-panache/src/main/java/io/quarkus/it/panache/defaultpu/TestEndpoint.java
index 07b56adcd78985..624d86daa926e5 100644
--- a/integration-tests/hibernate-orm-panache/src/main/java/io/quarkus/it/panache/defaultpu/TestEndpoint.java
+++ b/integration-tests/hibernate-orm-panache/src/main/java/io/quarkus/it/panache/defaultpu/TestEndpoint.java
@@ -1860,4 +1860,27 @@ public String testBug31117() {
         Assertions.assertEquals(1, Person.delete("\r\n  \n\ndelete\nfrom\n Person2\nwhere\nname = ?1", "foo"));
         return "OK";
     }
+
+    @GET
+    @Path("42416")
+    @Transactional
+    public String testBug42416() {
+        Person.deleteAll();
+        Person p = new Person();
+        p.name = "stef";
+        p.persist();
+
+        Person p2 = new Person();
+        p2.name = "stef";
+        p2.persist();
+
+        try {
+            Person found = Person.find("where name = ?1", "stef").singleResult();
+        } catch (jakarta.persistence.NonUniqueResultException e) {
+            return "OK";
+        } catch (org.hibernate.NonUniqueResultException e) {
+            e.printStackTrace();
+            return "KO";
+        }
+    }
 }